Gene 83138.m00054 (T.vaginalis)

83138.m00054

Species: T.vaginalis
Alias: TvagK0374, 83138.m00054
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
83138.m00054.AA Protein None 436 None Fasta, JSON
83138.m00054.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 83138.m00054.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83138.m00054.AA AGC 116-367 29 5.4e-148 385.58 In-house 1-395 (395) Show / Hide 
Range on Protein: 116-367
Range on HMM: 1-395/395
Sequence Identity: 29% (119 aa)

FRIISVLGRGFYGKVMLVEKL------DTGKLYALKTVRKKK-LIEMG--QVDTIIAE------------RNLLFSIPP---------HPFIIS-AEFAF
|... |.|.| .|||.||.|       ||||.||.| ..||.  ...   .|. ...|            || |  .           ||||..   ..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTPSK--FYIGLEYAA---------GG-ELLHHLS---NLPVVPIEDTKLYMAE-------VVLALQHLHT-NHIVYRD-LKPENVLLDKSGHVKLTDFG
|....   |. .||.          || ||..||    .  . . | .. |.||       .||||..||  ..|..|| |||||.|||. ||.||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LCKEITEEG----------------------------------------------------AKTFCG--TAEYLAPEVVLRLGYGFKVDWWA--LGVLLY
||||.  .|                                                    ..||||  |.||.|||..    ||. .|||.  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EILFAGTPFYDDN----------QAVLFDNIV------NEEPNYP----------KFGHKAAIDLIKLLLQKEPENRPD----------FEQIKEHAFF
| |.  .|||.||          .. .|..|       |... .|          ..  . | |||| ||.|.||.|.           .|.||.| .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 83138.m00054.AA Akt 116-367 42 1.3e-120 387.35 In-house 1-264 (264) Show / Hide 
Range on Protein: 116-367
Range on HMM: 1-264/264
Sequence Identity: 42% (113 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLY-ALKTVRKKKLIEMGQVDTIIAERNLLFSIPPHPFIISAEFAFQTPSKFYIGLEYAAGGELLHHLSNLPVVPI
|... |||.| .|||.||.| ||.|.| |.|  .|...|...||  ...|||.|  .  ||||..  ..|||. | |. ..|. ||||  ||.  .. . 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN-HPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSE

EDTKLYMAEVVLALQHLHTNHIVYRD-LKPENVLLDKSGHVKLTDFGLCK-E-ITE-EGAKTFCGTAEYLAPEVVLRLGYGFKVDWWA-LGVLLYEILFA
. .. | ||..||..||| . |.||| |||||.|.|| ||..|||||||| . |.. . .||||||.||||||. .  |.. .||||. ||...|| .. 
DRARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCG

GTPFYDDNQAVLFDNIVNEEPNYP--KFGHKAAIDLIKLLLQKEPENRP-----DFEQIKEHAFF
  |||.... ..|..| |.. ..|  ..  ... |||. ||.| |..|.     | ..||.| .|
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 83138.m00054.AA AktR 116-367 42 1e-110 374.14 In-house 1-268 (268) Show / Hide 
Range on Protein: 116-367
Range on HMM: 1-268/268
Sequence Identity: 42% (113 aa)

FRIISVLGRGFYGKVMLVEKL-DTGKLYALKTVRKKKLIEMGQVDTIIAERNLLFSIPPHPFIISAEFAFQTPSKFYIGLEYAAGGELLHHLSNLPVVPI
|... .||.| .|||.||.|. |..|.||.| ..|||.||  | . .| ||| . ..  ||||.  ...||| .| .. .|| .||||..||..      
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EDTKLYMAEVVLALQHLHTN-HIVYRDLKPENVLLDKSGHVKLTDFGLCK-EIT---EEGAKTFCGTAEYLAPEVVLR-LGYGFKVDWWALGVLLYEILF
|... |.|...|||..|| . .|.|||||||| |||. ||||.||||| | ..    .| |..|||| ||.|||....  |... |||||.|...||...
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

AGTPFYDDNQAVLFDNIVNEE---PNYPKFGHKAAIDLIK-LLLQKEPENRP-----DFEQIKEHAFF
  .|||..||  .|..| ...   ..||.   ... |||.  ||.| |..|.     ..|.||.| .|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 83138.m00054.AA SGK 116-367 40 2.5e-110 341.99 In-house 1-283 (283) Show / Hide 
Range on Protein: 116-367
Range on HMM: 1-283/283
Sequence Identity: 40% (116 aa)

FRIISVLGRGFYGKVMLVEKLDT------------------GKLYALKTVRKKKLI-------EMGQVDTIIAERNLLFSIPPHPFIISAEFAFQTPSKF
|....|.| | .|||..|.. |.                  .|.||.|  .|.  |          ..  | |||| . .   ||||..  .||||. | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YIGLEYAAGGELLHHLSNLPVVPIEDTKLYMAEVVLALQHLHTNHIVYRDLKPENVLLDKSGHVKLTDFGLCK-EI-TEEGAKTFCGTAEYLAPEVVLRL
|  ..|. |||.  ||      |    . |.||.|.|| .||   |.||||||||.|||  ||..|||||||| .| |... .||||| ||||||| .  
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

GYGFKVDWWALGVLLYEILFAGTPFYDDNQAVLFDNIVNEEPNYPKFGHKAAIDLIKLLLQKEPENR----PDFEQIKEHAFF
...  |||| || .||| ..   |||. | . ..||| |.. . |..   .| |||..||||.|..|     ||..||.| ||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 83138.m00054.AA RSK 119-367 38 1.2e-96 327.43 In-house 1-278 (278) Show / Hide 
Range on Protein: 119-367
Range on HMM: 1-278/278
Sequence Identity: 38% (107 aa)

ISVLGRGFYGKVMLVEKL---DTGKLYALKTVRKKKLIEMGQ-VDTIIAERNLLFSIPPHPFIISAEFAFQTPSKFYIGLEYAAGGELLHHLSNLPV---
..|||.| |||| |. |    |||..|| | ..|.|..     . .  .||| |  .  ||||..   ||||..|.|. .||  ||||. ||..      
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

VPIEDTKLYMAEVVLALQHLHTNHIVYRDLKPENVLLDK---SGHVKLTDFGLCKE-ITE--EGAKTFCGTAEYLAPEVVL----RLGYGFKVDWWALGV
   .. . ||||.|||..|||. .|..|||||||.|.|    .||.||||||.||.   .  . ..|||.|.||.|||..     . |..  .||| |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LLYEILFAGTPFYD---DNQAVLFDNIVNEE--PNYP--KFGHKAAIDLIKLLLQKEPENRPD-----FEQIKEHAFF
|.|| |.  .||.    .|.......| . .  .. |  ..  ..| |||. .|...|..|.       |.||.|..|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 83138.m00054.AA S_TKc 116-367 31 4e-94 319.92 SMART 1-231 (231) Show / Hide 
Range on Protein: 116-367
Range on HMM: 1-231/231
Sequence Identity: 31% (85 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVRKKKLIEMGQVDTIIAERNLLFSIPPHPFIISAEFAFQTPSKFYIGLEYAAG--GELLHHLSNLPV--
..|. ..|.| .|||... . .||...|.| ..          ..|. |...| .   ||.|.    .||. ...|. .||. |  |.|.... . .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----VPIEDTKLYMAEVVLALQHLHTNHIVYRDLKPENVLLDKSGHVKLTDFGLCKEITEEGAKTFCGTAEYLAPEVVLRLGYGF-KVDWWALGVLLYEI
     |  ... ||.....||...| ..|..|||||||.|||.  |.|..||||....     .||||| .|.||||.   |||. |.|||..|..||| 
LRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

LFAGTPFYDDNQAVLFDNIVNEEPNYPKFGHKAAIDLIKLLLQKEPENRPDFEQIKE-------HAFF
|   .||.  .....|..|.           . |.|.|. .|||.||.||   .. .       | .|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 83138.m00054.AA RSK-Unclassified 116-367 35 2.8e-89 280.57 In-house 1-283 (283) Show / Hide 
Range on Protein: 116-367
Range on HMM: 1-283/283
Sequence Identity: 35% (101 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVRKKKLIEMGQVDTIIAERNLLFSIPPHPFIISAEFAFQTPSKFYIGLEYAAGGELLHHLS--NLPVVP
|  .  .|.|  ||| ||.| || ..||.|   |.|.|    .  .. |.| . ..  ||||.   ..|||  . |  .||  ||..  ||       . 
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIM-ATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFC

IEDTKLYMAEVVLALQHLHTNHIVYRDLKPENVLLDKSGHVKLTDFGLCKEI-----------------------TEEGAKTFCGTAEYLAPEVVLRLGY
 .| . |..||..|| .||   ..||||||.|..|...|||.||||.| ..                           ... |||| ||||||.. | | 
EDDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGH

GFKVDWWALGVLLYEILFAGTPFYDDNQAVLFDNIVNEEPNYP--KFGHKAAIDLIKLLLQKEPENRP-----DFEQIKEHAFF
.  |||| ||...||.||  .|.| .|.  .| ||  ..   |  ..  . . |||| |||. |  |      | . || | ||
TKAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 83138.m00054.AA PKC 116-367 39 5.8e-89 288.48 In-house 1-262 (262) Show / Hide 
Range on Protein: 116-367
Range on HMM: 1-262/262
Sequence Identity: 39% (103 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVRKKKLIEMGQVDTIIAERNLLFSIPPHPFIISAEFAFQTPSKFYIGLEYAAGGELLHHLSNLPVVPIE
|. . |||.| .|||||.|. .| ..|| | ..|   |.   |.   .|.  |     |||  .    |||... .  .||  || | .|  .    . |
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

DTKLYMAEVVLALQHLHTNHIVYRDLKPENVLLDKSGHVKLTDFGLCKE--ITEEGAKTFCGTAEYLAPEVVLRLGYGFKVDWWALGVLLYEILFAGTPF
 .. | ||...||| ||.. |.||||| .|||||. ||.|..|||.|||    .. ..||||| .|.|||..    ||. |||||.|||.|| .    ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YDDNQAVLFDNIVNEEPNYPKFGHKAAIDLIKLLLQKEPENR----PD----FEQIKEHAFF
  ..   ||..| ...| ||.  .| | ...| ...|.||.|    |.    .. |.||.||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 83138.m00054.AA p70 116-367 38 6.4e-85 288.42 In-house 1-299 (299) Show / Hide 
Range on Protein: 116-367
Range on HMM: 1-299/299
Sequence Identity: 38% (116 aa)

FRIISVLGRGFYGKVMLVEKLD---TGKLYALKTVRKKK-LIEMGQVDTII-------------------------AERNLLFSIPPHPFIISAEFAFQT
|  . |||.| ||||..| |     |||.|| |  || | ..     .                            |||| | ..  ||||.   .||||
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEV-KHPFICDLHYAFQT

PSKFYIGLEYAAGGELLHHLSNLPVVPIEDTKLYMAEVVLALQHLHTNHIVYRDLKPENVLLDKSGHVKLTDFGLCKEITEEGAK------------TFC
 .| |  |||  ||||  ||    . . . .. |..|...||.|||.  |.||||||||..|.. |||.|||||||||  ..||.            |||
NGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFC

GTAEYLAPEVVLRLGYGFKVDWWALGVLLYEILFAGTPFYDDNQAVLFDNIVNEE--PNYPKFGHKAAIDLIKLLLQKEPENRPD-----FEQIKEHAFF
|| || |||...| |..  ||||.||.|.|  |  | ||  .| ..  | |      .. |    . . |||| || ..|  |        ..|.||.||
GTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 83138.m00054.AA PKA 116-367 40 1.1e-84 287.59 In-house 1-263 (263) Show / Hide 
Range on Protein: 116-367
Range on HMM: 1-263/263
Sequence Identity: 40% (106 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVRKKKLIEMGQVDTIIAERNLLFSIPPHPFII-SAEFAFQTPSKFYIGLEYAAGGELLHHLSNLPVVPI
| || .||.| .|.|||. . ..|. ||.|. .| . . . ||. .. |.| | .|  ||||. . .. ||.... |  .||..|||. ..| .    . 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNI-KHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSN

EDTKLYMA-EVVLALQHLHTNHIVYRDLKPENVLLDKSGHVKLTDFGLCKEITEEGAKTFCGTAEYLAPEVVLRL-GYGFKVDWWALGVLLYEILFAGTP
 ..|.| | ..||||. ||. .|.|||||||| |.|| ||.|.||||  |....   .| ||| ||||||....  |.|  |||||||.| || |.  .|
PHAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FYDD--NQAVLFDNIVNEEPNYPKFGHKAA---IDLIKLLLQKEPENRP---DF--EQIKEHAFF
|||.  ... ... |.| . ..| . ...|    |||| |||. .. |    ..  ..||.| .|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 83138.m00054.AA Pkinase 116-367 28 5.4e-83 286.83 Pfam 1-293 (293) Show / Hide 
Range on Protein: 116-367
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVRKKKLIEMGQVDTIIA--ERNLLFSIPPHPFIISAEFAFQTPSKFYIGLEYAAGG----ELLHHLS--
..|....|.| .|.| .  . .|||..|.|...|.  .....  | .   |  .. ..  ||.|.    .|..... |. .||. ||    .| ...|  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

NLPVV--PIEDTKLYMAEVVLALQHLHTNHIVYRDLKPENVLLDKSGHV----KLTDFGLCK---EITEEGAKTFCGTAEYLAPEVVL-RLGYGFKVDWW
.  ..  . .. | || ... .|...| . |..|||||||.|.|. ||.    |..||||.|   .   . ..||||| .|.||||.. . .|| |||.|
RHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

ALGVLLYEILFAGTPFYDD------NQAVLFDNIVNEEPNYPKFGH---------------------KAAIDLIKLLLQKEPENRPDFEQIKEHAFF
..|..||| |.  .||...      .| .....|   .. .. .                       ....|.|| .|.| |. || .|||..| .|
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 83138.m00054.AA PKN 116-367 42 1.8e-79 270.33 In-house 1-260 (260) Show / Hide 
Range on Protein: 116-367
Range on HMM: 1-260/260
Sequence Identity: 42% (112 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVRKKKLIEMGQVDTIIAERNLL--FSIPPHPFIISAEFAFQTPSKFYIGLEYAAGGELLHHLSNLPVVP
||.|.||||| .|||.|..   ||..||.| ..|. ..    |. ...|. ..   .   |||...    ||| .  .  .|||.||.|. |. .  | .
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEEHVCFVMEYAMGGDLMMHIHE-DVFS

IEDTKLYMAEVVLALQHLHTNHIVYRDLKPENVLLDKSGHVKLTDFGLCKEITEEGAK--TFCGTAEYLAPEVVLRLGYGFKVDWWALGVLLYEILFAGT
   .  |.| ||| ||.|| ..|.||||| .|.|||. |.||. |||||||    | .  ||||| |.|||||.    |   |||| ||||.||.|   .
EPRACFYAACVVLGLQYLHEHKIIYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLIYEMLVGEC

PFYDDNQAVLFDNIVNEEPNYPKFGHKAAIDLIKLLLQKEPENR-----PDFEQIKEHAFF
||  |.   .|| |||..  ||.|    ||.... ||.| || |      | |.|| ..||
PFPGDDEEEVFDCIVNDDVRYPRFLSVEAIAIMRRLLRKNPERRLGAGERDAEDIKMQPFF
Kinase 83138.m00054.AA TyrKc 116-367 18 1.5e-16 44.88 SMART 1-280 (280) Show / Hide 
Range on Protein: 116-367
Range on HMM: 1-280/280
Sequence Identity: 18% (54 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVRKKKLIEMGQVDTIIAERNLLFSI-PPHPFIISAEFAFQTP-------SKFYIGLEYAAGGELLHHL-
 . . .||.|..|.|.. .        | |.... .      .  .. | ... .. . || |.    .  ..          .| .||...| |...| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

SNLPVVPIEDTKLYMAEVVLALQHLHTNHIVYRDLKPENVLLDKSGHVKLTDFGLCKEITEE-------GAKTF----CGT----AEYLAPEVVLRLGYG
.. | .. .|   ..  .    ..|| .... |||   |.|... ..|| .||||...|...         ..     .|        .|||.     . 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

FKVDWWALGVLLYEIL-FAGTPFYD-----DNQAVLFDNIVNEEPNYPKFG---------HKAAIDLIKLLLQKEPENRPDFEQIKEHAFF
.| | |. ||...||. . ..| ..      . . .. .. . .   .            ...  ...|   . .||.|| |..|  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 83138.m00054.AA Pkinase_Tyr 194-307 26 2.1e-09 32.46 Pfam 86-208 (270) Show / Hide 
Range on Protein: 194-307
Range on HMM: 86-208/270
Sequence Identity: 26% (32 aa)

LEYAAGGELLHHLSN----LPVVPIEDTKLYMAEVVLALQHLHTNHIVYRDLKPENVLLDKSGHVKLTDFGLCKEITEEGAK-TFCGTAE----YLAPEV
.||...| ||..| .     . ....|   . ...  ....|. .... |||   |.|......|| .||||.. |....   .  | .      .|||.
MEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPEC

VLRLGYGFKVDWWALGVLLYEIL
     .  | | |. |||..||.
INYGKFTTKSDVWSFGVLMWEIF
Kinase 83138.m00054.AA S_TK_X 368-427 25 0.000785 8.63 SMART 1-79 (79) Show / Hide 
Range on Protein: 368-427
Range on HMM: 1-79/79
Sequence Identity: 25% (20 aa)

KGIDWDKVLR--KEVQPKNFRQVD-----ELDPENFCSDFTNEPPLDSEALPASSAYRD------------IDGFSFGG
.||||||...  ||..|    ..      . | .||  .||.|.| .. . |..|.  .              ||..  
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 83138.m00054.AA Pkinase_Tyr 349-367 36 0.361596 4.58 Pfam 254-270 (270) Show / Hide 
Range on Protein: 349-367
Range on HMM: 254-270/270
Sequence Identity: 36% (7 aa)

QKEPENRPDFEQIKEHAFF
...||.|| |..|  | ..
HYDPEDRPTFSEI--HEQL
Kinase 83138.m00054.AA Pkinase_Tyr 116-132 29 0.547436 3.97 Pfam 1-17 (270) Show / Hide 
Range on Protein: 116-132
Range on HMM: 1-17/270
Sequence Identity: 29% (5 aa)

FRIISVLGRGFYGKVML
 ... .||.| .|.|..
ITFGKKLGEGAFGEVYK