80612.m00071

Species: T.vaginalis
Alias: 80612.m00071, TvagK0360
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
80612.m00071.AA Protein None 228 None Fasta, JSON
80612.m00071.kin_dom Protein Kinase Domain None 82 None Fasta, JSON

Protein domain

Protein domains of 80612.m00071.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 80612.m00071.AA AGC 116-192 30 2.7e-32 79.49 In-house 1-110 (395) Show / Hide
Range on Protein: 116-192
Range on HMM: 1-110/395
Sequence Identity: 30% (34 aa)

FRIISVLGRGFYGKVMLVEKL------DTGKLYALKTVQKKK-LVECG--QVDTIISE------------RNLLFSIPP---------HPFIVS-AEFAF
|... |.|.| .|||.||.|       ||||.||.| ..||.  |.    .|. ...|            || |  .           |||||.   ..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTKSK--FYI
|.|..   |.
QDKDHTYLYF

Kinase 80612.m00071.AA Akt 116-192 43 6.1e-27 83.08 In-house 1-77 (264) Show / Hide
Range on Protein: 116-192
Range on HMM: 1-77/264
Sequence Identity: 43% (34 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLY-ALKTVQKKKLVECGQVDTIISERNLLFSIPPHPFIVSAEFAFQTKSKFYI
|... |||.| .|||.||.| ||.|.| |.|  .|..... .||  .. |||.|  .  |||||.  ..|||. | |.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCN-HPFIVNLHYSFQTQDKLYF

Kinase 80612.m00071.AA AktR 116-192 43 1.3e-26 94.76 In-house 1-78 (268) Show / Hide
Range on Protein: 116-192
Range on HMM: 1-78/268
Sequence Identity: 43% (34 aa)

FRIISVLGRGFYGKVMLVEKL-DTGKLYALKTVQKKKLVECGQVDTIISERNLLFSIPPHPFIVSAEFAFQTKSKFYI
|... .||.| .|||.||.|. |..|.||.| . |||..|  | . .| ||| . ..  |||||  ...||||.| ..
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFF

Kinase 80612.m00071.AA SGK 116-191 30 7.2e-25 73.34 In-house 1-101 (283) Show / Hide
Range on Protein: 116-191
Range on HMM: 1-101/283
Sequence Identity: 30% (31 aa)

FRIISVLGRGFYGKVMLVEKLDT------------------GKLYALKTVQKKKLV-------ECGQVDTIISERNLLFSIPPHPFIVSAEFAFQTKSKF
|....|.| | .|||..|.. |.                  .|.||.|  ||.  .          ..  | .||| . .   |||||.  .||||| | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

Y
|
Y

Kinase 80612.m00071.AA RSK-Unclassified 116-196 34 1.2e-21 64.28 In-house 1-80 (283) Show / Hide
Range on Protein: 116-196
Range on HMM: 1-80/283
Sequence Identity: 34% (28 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVQKKKLVECGQVDTIISERNLLFSIPPHPFIVSAEFAFQTKSKFYIGLIY
|  .  .|.|  ||| ||.| || ..||.|  .|.|..    .  .. |.| . ..  |||||   ..|||. . |  . |
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIM-ATTNHPFIVTLYHSFQTQDYLYLCMEY

Kinase 80612.m00071.AA PKN 116-188 37 1.6e-17 56.47 In-house 1-75 (260) Show / Hide
Range on Protein: 116-188
Range on HMM: 1-75/260
Sequence Identity: 37% (28 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVQKKKLVECGQVDTIISERNLL--FSIPPHPFIVSAEFAFQTKS
||.|.||||| .|||.|..   ||..||.| ..|. .|    |. ...|. ..   .   |||.|.    |||..
FRCIAVLGRGHFGKVLLSQYKHTGEYYAIKALKKQDIVARDEVESLMCEKRIFEVVNRMRHPFLVNLFACFQTEE

Kinase 80612.m00071.AA MAST 116-192 33 1.1e-16 50.05 In-house 1-76 (334) Show / Hide
Range on Protein: 116-192
Range on HMM: 1-76/334
Sequence Identity: 33% (26 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVQKKKLVECGQVDTIISERNLLFSIPPHPFIVSAEFAFQTKSKFYI
| .| ....| |||| ||.. .|....|.|.. |  .    .||. ..||| | ..   ||.|..  .||||.. ..
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNIL-AMYQNPFVVKMFYSFQTKNYLCM

Kinase 80612.m00071.AA Eta 116-197 34 1.9e-15 49.15 In-house 1-82 (261) Show / Hide
Range on Protein: 116-197
Range on HMM: 1-82/261
Sequence Identity: 34% (28 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVQKKKLVECGQVDTIISERNLLFSIPPHPFIVSAEFAFQTKSKFYIGLIYI
|  | |||.| .||||| |. .|. .||.| ..|  ..    |.  . |. .|     |||. .   .|||| . .  . |.
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYV

Kinase 80612.m00071.AA RSK 119-192 43 3.9e-15 52.07 In-house 1-78 (278) Show / Hide
Range on Protein: 119-192
Range on HMM: 1-78/278
Sequence Identity: 43% (34 aa)

ISVLGRGFYGKVMLVEKL---DTGKLYALKTVQKKKLVECGQ-VDTIISERNLLFSIPPHPFIVSAEFAFQTKSKFYI
..|||.| |||| |. |    |||..|| | ..|.|.|     . .   ||| |  .  |||||.   ||||..|.|.
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYL

Kinase 80612.m00071.AA PKA 116-191 38 3.6e-14 53.41 In-house 1-76 (263) Show / Hide
Range on Protein: 116-191
Range on HMM: 1-76/263
Sequence Identity: 38% (30 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVQKKKLVECGQVDTIISERNLLFSIPPHPFIV-SAEFAFQTKSKFY
| || .||.| .|.|||. . ..|. ||.|.  | . |   ||. ...|.| | .|  ||||| . .. ||. .. |
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNI-KHPFIVKKMYWTFQDDRYLY

Kinase 80612.m00071.AA Pkinase 116-192 25 3.3e-10 37.16 Pfam 1-77 (293) Show / Hide
Range on Protein: 116-192
Range on HMM: 1-77/293
Sequence Identity: 25% (20 aa)

FRIISVLGRGFYGKVMLVEKLDTGKLYALKTVQKKKLVECGQVDTIIS--ERNLLFSIPPHPFIVSAEFAFQTKSKFYI
..|....|.| .|.| .  . .|||..|.|.. |.   ....  | .   |  .. ..  ||.||    .|..|.. |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFEDKDHIYM