Gene 84285.m00236 (T.vaginalis)

84285.m00236

Species: T.vaginalis
Alias: 84285.m00236, TvagK0378
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
84285.m00236.AA Protein None 430 None Fasta, JSON
84285.m00236.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 84285.m00236.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 84285.m00236.AA AGC 115-365 30 5.1e-148 385.66 In-house 1-395 (395) Show / Hide 
Range on Protein: 115-365
Range on HMM: 1-395/395
Sequence Identity: 30% (120 aa)

FRIISVIGRGYYGKVMLVQKK------DSGELFAIKYIRKSR--------LNDDNGSS--------VIAERNILMKVR----------HPFIVN-LCFAF
|... |||.| .|||.||.||      |.|...|.| ..|..          . . .         | .|||||.|..          |||||. | ..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTETK--VYLGLEYAA---------GG-ELFYHM--D-QVGTIPIDDARLYIAE-------IGLALQHLHS-IGIVYRD-LKPENILFDEKGHIKLTDFG
|....  .|. .||.          || |||.|.  . . |. . . || |.||       | |||..|||  ||..|| |||||||.||.|||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKSLDTSE---------------------------------------------------STTTFCG--TCEYLAPEIVTQQPYSYKVDEWA--LGVLAF
|.| . ...                                                    |.||||  | ||.||||.    |.. .| |.  ||.| .
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMIFGQTPFADEN----------KVYLFDKIV------SEDPEFPFL----------CDFKVTNFILRLLTKDPEKRPS----------FAEVQDDPFF
||..|..|| ..|          .  .|.||       .....|||            .    ..| .||.||||||.           . |... |.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 84285.m00236.AA Akt 115-365 43 3.1e-114 366.59 In-house 1-264 (264) Show / Hide 
Range on Protein: 115-365
Range on HMM: 1-264/264
Sequence Identity: 43% (115 aa)

FRIISVIGRGYYGKVMLVQKKDSGELF-AIKYIRKSRLNDDNG-SSVIAERNILMKVRHPFIVNLCFAFQTETKVYLGLEYAAGGELFYHMDQVGTIPID
|... |.|.| .|||.||.|||..... |.| ..|... . |    ...||||| ...||||||| ..|||..| |. ..|. |||||||. . .... |
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

DARLYIAEIGLALQHLHSIGIVYRD-LKPENILFDEKGHIKLTDFGLSKSL-DTS-ESTTTFCGTCEYLAPEIVTQQPYSYKVDEWA-LGVLAFEMIFGQ
 || |.||| ||..|||| .|.||| ||||||| |..|||.||||||.|    .  . |.||||| |||||||  .. .. .|| |. ||.. .||..|.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

TPFADENKVYLFDKIVSEDPEFP--FLCDFKVTNFILRLLTKDPEKRP-----SFAEVQDDPFF
 || ....  .|.|| ... .||     . .  ..| .||.|||.||.        |....|.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 84285.m00236.AA SGK 115-365 40 2.1e-109 339.08 In-house 1-283 (283) Show / Hide 
Range on Protein: 115-365
Range on HMM: 1-283/283
Sequence Identity: 40% (116 aa)

FRIISVIGRGYYGKVMLVQKKDS------------------GELFAIKYIRK-SRL-------NDDNGSSVIAER-NILMKVRHPFIVNLCFAFQTETKV
|....||| | .|||..|..||                   . ..|.| ..| ...       .      . ||| .|| ...||||||| .||||..| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YLGLEYAAGGELFYHMDQVGTIPIDDARLYIAEIGLALQHLHSIGIVYRDLKPENILFDEKGHIKLTDFGLSK-SLDTSESTTTFCGTCEYLAPEIVTQQ
|. ..|. |||.|||.   .  | | || | ||| .|| .|||. |.|||||||||| | .||..||||||.|    |.. |.||||| ||||||.   |
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYSYKVDEWALGVLAFEMIFGQTPFADENKVYLFDKIVSEDPEFPFLCDFKVTNFILRLLTKDPEKR----PSFAEVQDDPFF
|..  || | || . .||..|  || . ||  ..|.| ...  .|     .    |  ||.|||.||      |.|... |||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 84285.m00236.AA AktR 115-365 41 1.9e-108 366.59 In-house 1-268 (268) Show / Hide 
Range on Protein: 115-365
Range on HMM: 1-268/268
Sequence Identity: 41% (111 aa)

FRIISVIGRGYYGKVMLVQKK-DSGELFAIKYIRKSRLNDDN-GSSVIAERNILM-KVRHPFIVNLCFAFQTETKVYLGLEYAAGGELFYHMDQVGTIPI
|... ..|.| .|||.||||| |.....|.| |.|. . . |  . .| ||||.  ...|||||.| ..|||..| .. .|| .|||||.|  . ...  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DDARLYIAEIGLALQHLHSI-GIVYRDLKPENILFDEKGHIKLTDFGLSK---SLDTSESTTTFCGTCEYLAPEIVTQ-QPYSYKVDEWALGVLAFEMIF
..|| |.|.| |||..||.   |.|||||||||| || ||.|.|||||||     . .| ...|||| ||.|||..|. ... . || ||.|.. .||..
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GQTPFADENKVYLFDKIVSED-PEFPFLCDF--KVTNFIL-RLLTKDPEKRPS-----FAEVQDDPFF
|..|| ..|. ..|.|| ...  .||.  .|  .  ..|  .|| |.|.||.      . |. . |.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 84285.m00236.AA S_TKc 115-365 36 7.3e-99 335.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 115-365
Range on HMM: 1-231/231
Sequence Identity: 36% (98 aa)

FRIISVIGRGYYGKVMLVQKKDSGELFAIKYIRKSRLNDDNGSSVIAERNILMKVRHPFIVNLCFAFQTETKVYLGLEYAAG--GELFYHMDQVGT----
..|. .||.| .|||.....|..|...||| |.          ... |..||.| .||.||.|  .||. ...|. .||. |  |.|| .... |.    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--IPIDDARLYIAEIGLALQHLHSIGIVYRDLKPENILFDEKGHIKLTDFGLSKSLDTSESTTTFCGTCEYLAPEIVTQQPYSY-KVDEWALGVLAFEMI
  .|  .|| |...| .||...|| ||..|||||||||.||  |||..||||.. |      |||||| .|.|||..   .|.. |.| |..|.. .||.
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

FGQTPFADENKVYLFDKIVSEDPEFPFLCDFKVTNFILRLLTKDPEKRPSFAEVQD-------DPFF
 |..||   .   .|.||.          .  . .|| ..|.|||||||.  |.         .|.|
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 84285.m00236.AA RSK 118-365 39 9.2e-99 334.42 In-house 1-278 (278) Show / Hide 
Range on Protein: 118-365
Range on HMM: 1-278/278
Sequence Identity: 39% (109 aa)

ISVIGRGYYGKVMLVQKK---DSGELFAIKYIRKSRLNDDN--GSSVIAERNILMKVR-HPFIVNLCFAFQTETKVYLGLEYAAGGELFYHMDQVGT---
..| |.| |||| |..|.   |.| ..| | ..|. .   .     . .|||||. .. |||||.|  |||||.|.|| .||  |||||.|  . ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

IPIDDARLYIAEIGLALQHLHSIGIVYRDLKPENILFDE---KGHIKLTDFGLSKSLDTS--ESTTTFCGTCEYLAPEIVT---QQP-YSYKVDEWALGV
.  |.|. |.||| ||..|||. ||..|||||||||.|.    |||||||||..| .. .  . | |||.| ||.|||...   ||  ..  .| | |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LAFEMIFGQTPFAD---ENKVYLFDKIVSED--PEFP--FLCDFKVTNFILRLLTKDPEKRPS-----FAEVQDDPFF
| .|| .|..||.    .|.  ....| . .  ...|          ..| ..|..||.||..      .|....|.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 84285.m00236.AA Ciliate-E2b 115-365 32 4.7e-90 273.81 In-house 1-272 (272) Show / Hide 
Range on Protein: 115-365
Range on HMM: 1-272/272
Sequence Identity: 32% (89 aa)

FRIISVIGRGYYGKVMLVQK-KDSGELFAIKYIRKSRLNDDN-GSSVIAERNILMKVRHPFIVNLCFAFQTETKVYLGLEYAAGGELFYHMDQVG--TIP
. .|   |.| .| | ||.. |.. ...|.| | |...   |   . . | |.| |. ||||...  .|... ..|. .|.  |.|||  . ..|   . 
MIYIKKLGFGQFGSVYLVWNTKNTKQYYAMKCISKNQIIQQNMEKHMLQEKNVLEKCNHPFIMKFIRSFKDDQHMYFMMEFCNGMELFDVIREIGRLLLS

IDDARLYIAEIGLALQHLHSIGIVYRDLKPENILFDEKGHIKLTDFGLSKSLDTSES----TTTFCGTCEYLAPEIVT-----QQPYSYKVDEWALGVLA
  |.. |||.| |.|. ||. .|.|||.|||||. |.||..|| |.|..| ......    |.| .|| .|.||||..     ...|.|||| |..|.  
TYDSQFYIASICLCLEYLHNQNIIYRDIKPENIMVDHKGYMKLIDMGTAKHMYKKNEQMTRTFTIIGTPHYMAPEIIQSLQPGGKGYTYKVDIWSVGICL

FEMIFGQTPFAD--ENKVYLFDKIVSE--DPEFPFLCDFKVT--NFILRLLTKDPEKRP--SFAEVQDDPFF
.|...|. |.|   ..   .  .|...  . .||  |  |.   ...|..| | || |.  |..     |.|
YEFMCGYVPWAEDVQDPYEIYQEIIKKYDEIQFPSYCKDKMADKKLMLQCLQKMPEVRLGGSYSWLKSHPWF
Kinase 84285.m00236.AA PKA 115-365 39 1.4e-89 303.92 In-house 1-263 (263) Show / Hide 
Range on Protein: 115-365
Range on HMM: 1-263/263
Sequence Identity: 39% (104 aa)

FRIISVIGRGYYGKVMLVQKKDSGELFAIKYIRKSRLNDDNGSS-VIAERNILMKVRHPFIVN-LCFAFQTETKVYLGLEYAAGGELFYHMDQVGTIPID
| || ..|.| .|.|||...|.||. .|.| ..|..  . .    |. |.|||. ..|||||. . . ||.... |. .||..|||.|...  .|  . .
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

DARLYIA-EIGLALQHLHSIGIVYRDLKPENILFDEKGHIKLTDFGLSKSLDTSESTTTFCGTCEYLAPEIVTQQ-PYSYKVDEWALGVLAFEMIFGQTP
.|..|.| .| |||. |||  |.|||||||||| |..||||.|||| .| .|.   | | ||| |||||||..   ..   || ||||.| .|| .| .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FADE--NKVYLFDKIVSEDPEFPFLCDFKV---TNFILRLLTKDPEKRP---SF--AEVQDDPFF
| |.  ..  ...||.. . .||   | ..     .| .||..|..||    ..    . . ..|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 84285.m00236.AA CAMK 120-365 22 4.9e-89 286.98 In-house 1-425 (425) Show / Hide 
Range on Protein: 120-365
Range on HMM: 1-425/425
Sequence Identity: 22% (95 aa)

VIGRGYYGKVMLVQKKDSG------------ELFAIKYIRKSRLNDD--------------------------NGSSVIAERNILMK-------VRHPFI
..||| .||| |.. | ..            . .||| | |..| |.                          .  .|  | .|..|       ..|| |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNLCFAFQ------------TETK--------VYLGL---EYAAGGEL----FYHMDQV---------------GTIPIDDARLYIAEIGLALQHLHSIG
..|  ...            | .|        .|. .   ||. ||||    | .  .                | .. ..|| |.  |  |....|| .
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IVYRDLKPENILFDEK-----------------GHIKLTDFGLSKSLDTSE------------------------STTTFCGTCEYLA-PEIVTQ-----
|| |||||||||.|..                 . ||..|||... .| .|                          .||||| || | ||.. .     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------QPYSYKVDEWALGVLAFEMIFGQTPFADE-------------NKVYLFDKIVSEDPEFP--FLCDFK----------------------VT
         ..|..|.| |..||. . |  |  || ..             |   || || . . .||  .. .                        . 
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NFILRLLTKDPEKRPSFAEVQDDPFF
..| ..|..|||||.. ... ..|..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 84285.m00236.AA p70 115-365 37 1.2e-88 300.79 In-house 1-299 (299) Show / Hide 
Range on Protein: 115-365
Range on HMM: 1-299/299
Sequence Identity: 37% (113 aa)

FRIISVIGRGYYGKVMLVQKKD---SGELFAIKYIRKSRL--NDDNGSSVI-------------------------AERNILMKVRHPFIVNLCFAFQTE
|  . |.|.| ||||..| |     .| ..| | .||     |     .                           ||||||  | ||||. | .||||.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKAKIVRNQKDTAHTREDEDKNDGNNNDNDDGLSKRLERTFAERNILEEVKHPFICDLHYAFQTN

TKVYLGLEYAAGGELFYHMDQVGTIPIDDARLYIAEIGLALQHLHSIGIVYRDLKPENILFDEKGHIKLTDFGLSK-SLDTSES----------TTTFCG
 | || |||  |||||.|    |. . | |. | .|| .||.|||. ||.||||||||.. ...||..||||||.| |.  ..           | ||||
GKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLTDFGLCKESIHDGAVDEEDPENVNATHTFCG

TCEYLAPEIVTQQPYSYKVDEWALGVLAFEMIFGQTPFADENKVYLFDKIVSED--PEFPFLCDFKVTNFILRLLTKDPEKRPS-----FAEVQDDPFF
| || ||||..   ..  || |.||.| . |  |. ||  ||.    |||      .. |.         | .|| ..| .|        |..| .|||
TIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDLIKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 84285.m00236.AA PKC 115-365 40 6.9e-87 281.66 In-house 1-262 (262) Show / Hide 
Range on Protein: 115-365
Range on HMM: 1-262/262
Sequence Identity: 40% (105 aa)

FRIISVIGRGYYGKVMLVQKKDSGELFAIKYIRKSR-LNDDNGSSVIAERNIL-MKVRHPFIVNLCFAFQTETKVYLGLEYAAGGELFYHMDQVGTIPID
|. . |.|.| .|||||. .|.. |..||| ..|   . ||   .. .|. .|    .||| ..|   |||. . .  .||  || | .|. |..  .  
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

DARLYIAEIGLALQHLHSIGIVYRDLKPENILFDEKGHIKLTDFGLSKSLDTSESTT-TFCGTCEYLAPEIVTQQPYSYKVDEWALGVLAFEMIFGQTPF
 || | ||| .||| ||. ||.||||| .|.| |. ||||..|||..|   . ..|| ||||| .|.||||.  |.|.  || ||.||| .||  || ||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

ADENKVYLFDKIVSEDPEFPFLCDFKVTNFILRLLTKDPEKR----PS----FAEVQDDPFF
  |.  .||. |  ..| .|     . .. .  ..||.||||    |.    . .... |||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 84285.m00236.AA Pkinase 115-365 30 4.7e-86 296.98 Pfam 1-293 (293) Show / Hide 
Range on Protein: 115-365
Range on HMM: 1-293/293
Sequence Identity: 30% (89 aa)

FRIISVIGRGYYGKVMLVQKKDSGELFAIKYIRKSRLNDDNGSSVIA--ERNILMKVRHPFIVNLCFAFQTETKVYLGLEYAAGG----ELFYHMD--QV
..|...||.| .|.| . ..|..|...|.| |.|.. ...   . .   |  |. ...||.|| |  .|......|. .||. ||    .|| ..   . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GTI--PIDDARLYIAEIGLALQHLHSIGIVYRDLKPENILFDEKGHI----KLTDFGLSKS--LDTSESTTTFCGTCEYLAPEIVT-QQPYSYKVDEWAL
|..  . .... |. .|  .|...|| ||..|||||||||.|..|||    |..||||.|   .  .. .|||||| .|.|||..  .|.|..||| |..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLAFEMIFGQTPFADE------NKVYLFDKIVSEDPEFPFLCD---------------------FKVTNFILRLLTKDPEKRPSFAEVQDDPFF
|.. .||..|..|| ..      .. .....| . ...|..  .                          || ..|.|||.|||.....  .|.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 84285.m00236.AA TyrKc 115-363 19 2.5e-16 41.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 115-363
Range on HMM: 1-280/280
Sequence Identity: 19% (57 aa)

FRIISVIGRGYYGKVMLVQKKDSGELFAIKYIRKSRLNDDNGSSVIAERNILMKV--RHPFIVNLCFAFQTE-------TKVYLGLEYAAGGELFYHM-D
 . . ..|.| .|.|.. . |   .  |.| ....          . | .|..|.  .|| ||.|  .  ..         ... .||...| |  .  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

QVGTIPIDDARLYIAEIGLALQHLHSIGIVYRDLKPENILFDEKGHIKLTDFGLSKSLDTS------ESTTTFCG--TCE------YLAPEIVTQQPYSY
  .... .|   .   |    ..||| ... |||   |.| .|....| .|||||. ..        ... .  .   .        .|||      .. 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KVDEWALGVLAFEMI-FGQTPFAD-----ENKVYLFDKIVSE-DPEFPFL--------CDFKVTNFILRLLTKDPEKRPSFAEVQDDP
| | |. ||. .|.  .||.|  .      .   .. .. .   .. |          |  .. . ...    |||.||.|.|. .. 
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 84285.m00236.AA S_TK_X 366-426 32 1.5e-12 48.9 SMART 1-79 (79) Show / Hide 
Range on Protein: 366-426
Range on HMM: 1-79/79
Sequence Identity: 32% (26 aa)

AGLDWDKVYK--REYTPRFIPKVK----DPLHPTNFDPEFTNEIPTDSLCAPGLGDIGN------------IPGFSFME
.|.||||.|.  .|..| |.||.|    .|    |||||||.| |... . |.| .. .             .||... 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 84285.m00236.AA Pkinase_C 385-428 36 0.000149 19.36 Pfam 1-46 (46) Show / Hide 
Range on Protein: 385-428
Range on HMM: 1-46/46
Sequence Identity: 36% (17 aa)

KVKDPLHPTNFDPEFTNEIPTDSL---CAPGLGDIGNIPGFSFMESK
.||.|.   |||||||.| |.|.    .    ||  .  ||..  ..
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase 84285.m00236.AA Pkinase_Tyr 115-270 20 0.000237 15.36 Pfam 1-171 (270) Show / Hide 
Range on Protein: 115-270
Range on HMM: 1-171/270
Sequence Identity: 20% (35 aa)

FRIISVIGRGYYGKVMLVQKK----DSGELFAIKYIRKSRLNDDN--GSSVIAERNILMKV-RHPFIVNLCFAFQ-TETK--VYLGLEYAAGGELFYHMD
 ... ..|.| .|.|..   |    . .   |.| . |    ...    . ..| .|...  .|| ||.|  .    .    .|. .||...| |  .  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

Q----VGTIPIDDARLYIAEIGLALQHLHSIGIVYRDLKPENILFDEKGHIKLTDFGLSKSL-DTSES-TTT
.     . ... |   . ..|  ....|.|.... |||   |.| .|....| .||||.. . ....  ...
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKR
Kinase 84285.m00236.AA Pkinase_Tyr 348-362 46 3.05713 1.44 Pfam 255-269 (270) Show / Hide 
Range on Protein: 348-362
Range on HMM: 255-269/270
Sequence Identity: 46% (7 aa)

KDPEKRPSFAEVQDD
.|||.||.|.|.. .
YDPEDRPTFSEIHEQ