Gene 97466.m00043 (T.vaginalis)

97466.m00043

Species: T.vaginalis
Alias: 97466.m00043, TvagK0614
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CRK7-like

Sequence

Name Sequence Type Origin Length Description Download
97466.m00043.AA Protein None 347 None Fasta, JSON
97466.m00043.kin_dom Protein Kinase Domain None 295 None Fasta, JSON

Protein domain

Protein domains of 97466.m00043.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 97466.m00043.AA CMGC 15-309 21 8.6e-91 298.51 In-house 1-513 (513) Show / Hide 
Range on Protein: 15-309
Range on HMM: 1-513/513
Sequence Identity: 21% (110 aa)

FRIIENIGVGAYGSVFKAFD--------------LETNEVVALKILK-AYDQKES---------LPLSFYRELGVLQNFK-----------------HEN
. ||. || |.|| |.|..|               ||||.||.|..| .   .|          .| . .||.  |....                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVSYGGVFRYPH-----------------EICITLEYCETDLQKQLSCQP---------LLQPNQ------------VKHLM------RQLLSGLA--EL
||.   .|....                 ....  ||...|| . .  ..          | . .            .|..|      .|.| ||.   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HQAG--YAHRDLKSSNILIKGGRTL--------------------KITDFGLSRQLNSK-----------------------QLTSKVTSLAYRAPELIL
|...    ||||| .||||    .|                    || ||||.|....                        ..|. | .. |||||..|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

GSKDYT---------TAIDIWSAGIIFYELCTGEK---------FP----------SACSDLSQLDKIFRVTGTPS------------PSSEDEKSPEIQ
|.|.||         |.||.||.| ||.|. || .         ||          .  |.. ||.|||.| |||.            .. |.|    |.
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

SDGDILCHLPN--------WRLASMLHI-----YPRTLEQLLKDKLPP-----------------------------------ELADAFDIITSMLSLNP
 .. ..   ..        |     ..|     .|.   . .|.. |.                                   .  .|.| .  || ..|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDP

SNRPSAVELLRNPFF
..|..| . |. |.|
DKRITAEQALQHPYF
Kinase 97466.m00043.AA S_TKc 15-309 25 6.5e-87 295.97 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-309
Range on HMM: 1-231/231
Sequence Identity: 25% (81 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQKESLPLSFYRELGVLQNFKHENIVSYGGVFRYPHEICITLEYCET---DLQKQLSCQPL----
..|.. || ||.|.|.|. . .|...||.||.|          ...||. .|.. .|.||| . .||.  ..... .|||..   || . .  ..     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LQPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQLNSKQLTSKVTSLAYRAPELILGSKDYTT-AIDIWSAGIIFYELC
  . . .....|.|....|. .|. |  ||||| .|||.    ..||.||||.|||     |. . .. |.|||..     |.. ..|.|| |.|.||..
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

TGEK-FPSACSDLSQLDKIFRVTGTPSPSSEDEKSPEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKDKLPPELADAFDIITSMLSLNPSNRPSAVEL
.|.  ||       |....|.. |                                                     .| |.|  .|  .|..||.| |.
CGYPPFP-------QMQMMFKKIG---------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EA

LR-------NPFF
|.        |.|
LQDEWDIKCHPWF
Kinase 97466.m00043.AA CDK 15-309 30 1e-80 257.91 In-house 1-284 (284) Show / Hide 
Range on Protein: 15-309
Range on HMM: 1-284/284
Sequence Identity: 30% (102 aa)

FRIIENIGVGAYGSVFKAFDLETN-----EVVALKILKAYDQ-----KESLPLSFYRELGVLQNFKHENIVSYGGVFRYP-----------HEICITLEY
. ..| || |.|| |.|| |..|.     ..|||| ..   .     || .| .  ||   |..  |.|||.   |.              . . .  ||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

CETDLQKQLSCQPLLQPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRT-----LKITDFGLSRQLNS--------KQLTSKVTSLAYRAPEL
...|| | ..         .|..|.|||.||. .|. .  ||||| .||||    .     |||.||||.|  ..        . .|..|  | ||||||
MDHDLKKYMD---------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPEL

ILGSKDYT--TAIDIWSAGIIFYELCT---GEKFPSACSDLSQLDKIFRVTGTPSPSS--EDEKSPEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKD
 ||||.|.  |.||.||.| ||.|. |   .. .    |.. ||.||||. |||....  . .| |.                                 
LLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------------

KLPPELADAFDIITSMLSLNPSNRPSAVELLRNPFF
          | . .|| ..|..| || . |  |.|
----------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase 97466.m00043.AA Pkinase 15-309 26 9.7e-75 259.41 Pfam 1-293 (293) Show / Hide 
Range on Protein: 15-309
Range on HMM: 1-293/293
Sequence Identity: 26% (85 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQKESLPLSFYR--ELGVLQNFKHENIVSYGGVFRYPHEICITLEYCET-----DLQKQLS--CQ
..|.. || |..|.|.|. .  |...||.||.|  ..|.. . .  |  |. ......|.||| . ..|... .|.. .||||      ||   .|   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

PLL--QPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIK-GGRT---LKITDFGLSR---QLNSKQLTSKVTSLAYRAPELILGSKDYTTAIDIWSA
  .  .....|. |.|.|.||. .|. |  |||||..||||.  | .   .||.||||..     |.  .|. . .. |.|||.|.|...|....|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GIIFYELCTGEKFPSAC----SDLSQLDKIFRVTGTPSPSSEDEK-----SPEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKDKLPPELADAFDIIT
|.|.||...|.   . .    . ..|. .|.|. |.| .......     .. ..                          . .. . .    .. |.|.
GCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H---------------------F-HWTF-HNWSEECKDFIK

SMLSLNPSNRPSAVELLRNPFF
..| ..|. ||.| ..|  |.|
WCLCKDPKKRPTAEQILQHPWF
Kinase 97466.m00043.AA CDC2 15-309 34 1.3e-73 225.51 In-house 1-301 (301) Show / Hide 
Range on Protein: 15-309
Range on HMM: 1-301/301
Sequence Identity: 34% (107 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQKES--LPLSFYRELGVLQNFK-HENIVSYGGVFRYPHEICITLEYCETDLQKQLS-CQPL---
.  || || | || |.|. |..||..||||  .   . |    | .  ||.  |.. | |.|||.   |.   . . .  ||.. || | .   .|    
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LQPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSR--QLNSKQLT--SKVTSLAYRAPELILGSKDYTTAIDIWSAGIIFYEL
..|. || .| |.|.|.. .|| .  ||||| .||||    ..|| ||||.|  . .....|    |  | |||||. ||.|.|.|..|.|| | ||.|.
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---CTGEKFPSACSDLSQLDKIFRVTGTPSPSSEDEKSPEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKDKLPPELA-DAFDIITSMLSLNPSNRPS
   .| . . .. |   || ||||. |||.    ... |.. .  |     |.|.   . .| |. ...    ..  .|  ...|.. .|| ..|..| |
FMDVTKKPLFHGDSEIDQLFKIFRILGTPN----EQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKK---KNQ-SCLDPEGIDLLMQMLQYDPQKRIS

AVELLRNPFF
| | |..|.|
AKEALQHPYF
Kinase 97466.m00043.AA CDK5 15-309 34 4.1e-61 191.66 In-house 1-287 (287) Show / Hide 
Range on Protein: 15-309
Range on HMM: 1-287/287
Sequence Identity: 34% (104 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQKESLPLSFYRELGVLQNFKHENIVSYGGVFRYPHEICITLEYCETDLQKQL-SCQPLLQPNQV
.  .| || | || |.|| . || |.||||  .  .  |  | .  ||  .|.  ||.|||    |      . .  |.|  || | . ||.  .... .
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNGEMDMHII

KHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQ--LNSKQLTSKVTSLAYRAPELILGSKDYTTAIDIWSAGIIFYELC-TGEKFP
| .| ||| |||  |.    |||||  | ||    .||  |||| |      .  .. |  | ||.|   .||| |.| ||.||.| || |.  .|    
KSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPLF

SACSDLSQLDKIFRVTGTPSPSSEDEKSPEIQSDGDILCHLPNWR-LASMLHIYPRTLEQLLKDKLPPELADAFDIITSMLSLNPSNRPSAVELLRNPFF
   ..  || .||...|||.     .| | |        .||... ..  . .||  ..| ..   |   .   |.   || .||  | || . |. |.|
PGNDVEDQLKRIFKIMGTPC----EDKWPSI-------TKLPDYKPNHQQYPMYP--AHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 97466.m00043.AA Ciliate-E2 15-309 17 3e-57 195.06 In-house 1-365 (365) Show / Hide 
Range on Protein: 15-309
Range on HMM: 1-365/365
Sequence Identity: 17% (74 aa)

FRIIENIGVGAYGSVFKAFDLETNE-----------------------VVALKILKAYDQKESLP-LSFYRELG----------VLQNFKHENIVSYGGV
. .|. || |..|||.|. . ....                        .|.||.| .. .. .  .. .||.           .|.. .| ||. .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FR--YPHEICITLEYCET-DLQK-----QLSCQPLLQ------PNQVKHLMRQLLS---------------GLAELHQAG-YAHRDLKSSNILIKGGRTL
|     . | . .|||.  ||..     .....  ..       ...|..|.|.|.               .| .||. .   |||.| .|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KITDFGLSRQLNSK---------------------------------QLTSKVTSLAYRAPELILG--------SKDYTTAIDIWSAGIIFYELCTGEK-
||.|||||.... .                                 .  . . .. | ||| . |        .|.|....||||.|.|.||...|.  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FPSACSDLSQLDKIFRVTGTPSPSSEDEKSPEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKDKLPPELA---------------------DAFDIIT
|                                                         ..| .. |.    .                     .. |.| 
F---------------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIK

S----MLSLNPSNRPS-AVELLRNPFF
     ||  .|..|.. . ..| .|.|
KFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 97466.m00043.AA MAPK 15-231 32 1.2e-53 183.84 In-house 1-256 (328) Show / Hide 
Range on Protein: 15-231
Range on HMM: 1-256/328
Sequence Identity: 32% (83 aa)

FRIIENIGVGAYGSVFKAFDLE------TNEVVALKILKAYDQKESLPLSFYRELGVLQNF-KHENIVSYGGVFRY------PH-----EICITLEYCET
..|...|| |||| |..|.| .      ... ||.| .    |.. .    |||.  |. | .||||..   .|.       ..     .|.|  |..||
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLQKQLSCQPLLQPNQVKHLMRQLLSG--LAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQLNSK----------------QLTSKVTSLAYRAP
||.. . .|. |    .. .| |.| |  |  .| |.  ||||| ||||.    .||| ||||.|.. ..                ..|  |.   ||||
DLHQIIKSQQPLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRAP

ELILG--SKDYTTAIDIWSAGIIFYELCT-GEKFPSACSDLSQLDKIFRVTGTPSP
|..|.  ...||.|.|.||.| || |. | .  .    . . |. .|. |.||||.
EIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSE
Kinase 97466.m00043.AA CDK-DD1 15-229 36 1.2e-52 160.59 In-house 1-219 (379) Show / Hide 
Range on Protein: 15-229
Range on HMM: 1-219/379
Sequence Identity: 36% (80 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQKESLPLSFYRELGVLQNFKH-ENIVSYGGVFRYP--HEICITLEYCETDLQKQLSCQP-LLQP
. ||. .| | |||||||    | . ||||. |   | . .|     |   |.  .|  |||     |      .  . .|| | || | .| .   .  
YQIISKCGQGIYGSVFKAIHKITHCMVALKNFKDWNQEDGEP---KVECKYLMQLRHCKNIVHLIDHFYNFKNSKYVMVFEYFEHDLWKFMSNHQCYMSL

NQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQLNS---KQLTSKVTSLAYRAPELILGSKDYTTAIDIWSAGIIFYELCTGE
 ..|  ..||| |. |.| .|  ||| | .| ||     |||||||..        | . ..| || ||.||| .||  |   ||.|| | |  |. |. 
PCIKCFFHQLLEGINECHNQGIMHRDIKPANLLINNRGDLKITDFGFTTYYTKRSEKHFSHQVVSLWYRPPELLMGSCQYGPEIDMWSVGCILMEMITNF

KFPSACSDLSQLDKIFRVTGTP
 .    ..  ||. |.   |.|
YMFAGSNEQQQLELICKLCGCP
Kinase 97466.m00043.AA STE 15-207 24 2.2e-49 170.35 In-house 1-265 (359) Show / Hide 
Range on Protein: 15-207
Range on HMM: 1-265/359
Sequence Identity: 24% (68 aa)

FRIIENIGVGAYGSVFKAFDL------ETNEV---------VALKILK-----AYDQK-----------ESLPLSFYRELGVLQNFK--HENIVSYGGVF
...|| || ||.|.|.|| .       .|.||         .| |...     ..| .           ..   .. .|. ......  |.||| | | .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKD-ENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

RYP-------HEICITLEYCE-TDLQKQLS-CQPLLQP-------------NQVKHLMRQLLSG-LAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLS
 .        .|..| .||..   | . .  .   ..|             .|...  ||.| | |. ||. .. |||.|..|||.      |..|||..
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVC

RQLNS-------------------KQLTSKVTSLAYRAPELILG-----SKDYTTAIDIWSAGIIFYELCTGE
 ||..                   |  |   |   . ||| |..     .|.|.|  |||| |.   |..||.
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP--WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase 97466.m00043.AA CRK7 110-233 31 8.2e-39 131.35 In-house 111-276 (343) Show / Hide 
Range on Protein: 110-233
Range on HMM: 111-276/343
Sequence Identity: 31% (52 aa)

PNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQLNS----KQLTSKVTSLAYRAPELILGSKDY------------------
..|.|..|.||| |.. .|. .  |||.| ||||.     .||.|||| | .||    ...| .|  | ||.||| || . |                  
HQQCKCFMKQLLEGMDYCHKKNFLHRDIKCSNILMNNQGEVKIADFGLARLYNSEEKRRPYTNRVITLWYRPPELLLGEERYTEQHILKELIRNIKSIQL

--------------------TTAIDIWSAGIIFYELCTGEKFPSACSDLSQLDKIFRVTGTPSPSS
                    ...||.|| | |. || |..    .   . ||.||... |.| | .
SLLISIYLKLTVQSSIFKKSGPEIDMWSCGCILGELFTKKPIFQGNNEMAQLEKIYKICGSPNPNN
Kinase 97466.m00043.AA PITSLRE 109-309 37 2.3e-38 133.76 In-house 104-295 (295) Show / Hide 
Range on Protein: 109-309
Range on HMM: 104-295/295
Sequence Identity: 37% (78 aa)

QPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSR--QLNSKQLTSKVTSLAYRAPELILGSKDYTTAIDIWSAGIIFYELCTG
.| ..| || |||.| . .|     ||||| ||.|.     ||| |||| |  . . | .|. |  | |||||| ||.| |.|..|.|| | || |. |.
KPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPELLLGCKKYSTPVDMWSVGCIFAEFITM

EKFPSACSDLSQLDKIFRVTGTPSPSSEDEKS-PEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKDKLP--PELAD-AFDIITSMLSLNPSNRPSAVE
.      |.. |...||   |||.     ||. | ...       ||.|..   .  ||   .  |. . |    . | .||    || .|| || .| .
KPLFQGKSEIDQINCIFKEMGTPT-----EKIWPGWTE-------LPHWKMMNNFPHYP---YNNLRKRFPAENHISDTGFDLLNQMLTYNPKNRITASD

LLRNPFF
 |  |.|
ALKHPWF
Kinase 97466.m00043.AA Pkinase_Tyr 15-210 27 1.4e-23 80.49 Pfam 1-214 (270) Show / Hide 
Range on Protein: 15-210
Range on HMM: 1-214/270
Sequence Identity: 27% (60 aa)

FRIIENIGVGAYGSVFKAFDL----ETNEVVALKILKAYDQKES-LPLSFYRELGVLQNF-KHENIVSYGGVFR--YPH-EICITLEYCET-DLQKQLSC
 .... .| ||.|.|.|.       .|.  || |.|| .  .|  .  .| ||. .. .. .|.|||.. ||      . .|.| .||..  || . |  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

----QPLLQPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQL----NS-KQLTSKVTSLAYRAPELILGSKDYTTAIDIWS
    .. | . .  .  .|  .|.. |.. .. ||||   |.|.. ... ||.||||.| .    .  .. ..        ||| |  .| .||. |.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGK-FTTKSDVWS

AGIIFYELCTGEKFP
 |.  .|..|  . |
FGVLMWEIFTYGEQP
Kinase 97466.m00043.AA TyrKc 15-309 21 7.2e-17 50.07 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-309
Range on HMM: 1-280/280
Sequence Identity: 21% (73 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQKESLPLSFYRELGVLQNF--KHENIVSYGGVFRYP-------HEICITLEYCET-DLQKQL-S
 . .. .| ||.| |.|.      . || | ||..         |.||. .. ..  .|.|||   || . .       . ..| .||..  ||.. | .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

CQPLLQPNQVKHLMRQLLSGLAELHQAGYAHRDLKSSNILIKGGRTLKITDFGLSRQLNSK-------QLTSK----VTS--LAYR--APELILGSKDYT
..| |.. .  . . |  .| . ||. .. ||||   |.|.. ..| ||.|||||| . ..       .  .|     .   | .|  ||| |  .| .|
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGK-FT

TAIDIWSAGIIFYELCTGEKFPS--------ACSDLSQLDKIFRVTGTPSP----SSEDEKSPEIQSDGDILCHLPNWRLASMLHIYPRTLEQLLKDKLP
|. |.|| |.  .|..|  . |           ... .. |  .    |      |                                           .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------------------------FV

PELADAFDIITSMLSLNPSNRPSAVELLRNPFF
   .. ..|...    .|..||.  |.    .|
CCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 97466.m00043.AA CRK7 15-75 39 8.7e-15 47.23 In-house 1-64 (343) Show / Hide 
Range on Protein: 15-75
Range on HMM: 1-64/343
Sequence Identity: 39% (25 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAYDQ---KESLPLSFYRELGVLQNFKHENIV
...|. || | || | || ...|.| |||| ..  .    ||  |    ||  .|. ..|.|||
YEMIMQIGEGTYGQVYKAKNKHTGEMVALKKVRMDNEKIKKEGFPITAIREIKILRQLNHQNIV
Kinase 97466.m00043.AA PITSLRE 15-76 40 5.5e-14 47.47 In-house 1-65 (295) Show / Hide 
Range on Protein: 15-76
Range on HMM: 1-65/295
Sequence Identity: 40% (26 aa)

FRIIENIGVGAYGSVFKAFDLETNEVVALKILKAY--DQKESLPLSFYRELG-VLQNFKHENIVS
| ..  |. |.|| |..| | .|.|.|||| ||      ||  |.   ||   .|   .|.|||.
FQCLNRIHEGTYGVVYRAKDKRTDEIVALKRLKMERQKEKEGFPITSLREINMILMALQHPNIVN
Kinase 97466.m00043.AA CDK-DD1 279-309 38 3.3e-07 17.64 In-house 349-379 (379) Show / Hide 
Range on Protein: 279-309
Range on HMM: 349-379/379
Sequence Identity: 38% (12 aa)

LADAFDIITSMLSLNPSNRPSAVELLRNPFF
| .  |.|  || |.| .| .. | |  |.|
LPSFLDLIERMLTLCPKKRINTKEALQHPWF
Kinase 97466.m00043.AA STE 281-309 35 6e-06 17.05 In-house 329-359 (359) Show / Hide 
Range on Protein: 281-309
Range on HMM: 329-359/359
Sequence Identity: 35% (11 aa)

DAFDIITSMLSLNPSNRPSAVELLR--NPFF
.  | |   |  .|..||.| .||.   ||.
EFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 97466.m00043.AA MAPK 281-309 34 2.3e-05 14.26 In-house 300-328 (328) Show / Hide 
Range on Protein: 281-309
Range on HMM: 300-328/328
Sequence Identity: 34% (10 aa)

DAFDIITSMLSLNPSNRPSAVELLRNPFF
.| | .  || ..|. | .. | |. |.|
QAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 97466.m00043.AA CRK7 280-309 33 7.8e-05 12.37 In-house 314-343 (343) Show / Hide 
Range on Protein: 280-309
Range on HMM: 314-343/343
Sequence Identity: 33% (10 aa)

ADAFDIITSMLSLNPSNRPSAVELLRNPFF
....|    || |.|. | .| | |. ..|
KECLDLLDKMLCLDPKKRFTAEECLQHDWF