89154.m00319

Species: T.vaginalis
Alias: 89154.m00319, TvagK0719
External Links:
Annotation:

Classification

Group: CMGC
Family: CK2

Sequence

Name Sequence Type Origin Length Description Download
89154.m00319.AA Protein None 342 None Fasta, JSON
89154.m00319.kin_dom Protein Kinase Domain None 286 None Fasta, JSON

Protein domain

Protein domains of 89154.m00319.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89154.m00319.AA CK2 46-331 38 3.1e-106 318.22 In-house 1-288 (288) Show / Hide
Range on Protein: 46-331
Range on HMM: 1-288/288
Sequence Identity: 38% (113 aa)

FQVISPVGTGKYSTVFLGR-MDGKKKC--AIKTLKNVPHFKIQKEICLLTKIKDIPNTVQLYGVVVDPLTDTFSIITDYLKSESPRTLFPKLTLENIRIL
..||. .| |||| || |. .. ..||   || || |   ||. ||  |.... .|| ..||..|.||   . ... .| .    |.|...||  .||  
YEVIRKIGRGKYSEVFEGINIKNNEKCKIVIKILKPVKKKKIKREIKILENLNGGPNIIKLYDIVKDPYSKVPALVFEYVNNTDFRQLYQTLTDYDIRYY

MWQLLTCLNESHKRGIMHRDVKPGNILFGQNRKSMKLIDWGLGDFYLAKEAYSPRVSTLRYKAPELLLNYQYYDYGIDVWGAGCVLAEMLV-RFPFFEGR
| .||  |  .|. ||||||||| ||.   ... ..|||||| .||  .. |  || .  ||.||||..|||||| .|.|  ||..| |.. . |||.| 
MFELLKALDYCHSMGIMHRDVKPHNIMIDHEKRKLRLIDWGLAEFYHPGQDYNVRVASRYYKGPELLVDYQYYDYSLDMWSLGCMFASMIFKKEPFFHGH

DIDEMVGDVSSVCGTNAITAYVNKYGLQLTPEMQKNLSNTQTPQFNKLTQNPSFNQAKNDHDALDLLQKLLTVDHEERITAAEALEHKFF
|  .   ..  | ||. . .|..|||..|.|.... . . .  ..... ..   . |..  .|.|.| |.|  ||.||||| ||.||..|
DNYDQLVKIVKVLGTEDLYKYLDKYGIHLDPQFHDIMQQHKKKPWERFIHQENKHLAHP--EAIDFLDKMLRYDHQERITAKEAMEHPYF

Kinase 89154.m00319.AA CMGC 46-331 16 1.3e-74 244.36 In-house 1-513 (513) Show / Hide
Range on Protein: 46-331
Range on HMM: 1-513/513
Sequence Identity: 16% (84 aa)

FQVISPVGTGKYSTVFLGRM---------------DGKKKCAIKTLKNVPHFKIQ---------------KEICLLTKIK----------------DIPN
...|...| | |..|. .|                ......||| .||.. ...|                || .| ...                . .|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

TVQLYGVVVDPLTD---------------TFSIITDYLKS------ESPRTL------------------------FPKLTLENIRILMWQLLTCLN--E
 |.|| ..... .|                . ....|.        .. ...                          .... .||  |.|.|..|.   
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

SHKRG--IMHRDVKPGNILFGQNRKSM-------------------KLIDWGLGDFYLAK----------------------EAYSPRVSTLRYKAPELL
 |...  |.||| || |||. .| ..                    |..|.||  .|                         ..|...|.|. |.|||.|
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

LNYQYYD---------YGIDVWGAGCVLAEMLVR--------FPFFE-----------GRDIDEMVGDVSSVCG------------------TNAITAYV
|....|.         ..||.|..||..|||. .         |.|            |..  ..      |.|                  .. .  ..
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMI

NKYGLQLTPE----------MQKN----------LSNTQTPQFNKLTQNPSF----------------NQAKND------------HDALDLLQKLLTVD
.... ...|.          . .           . . . . ...|  . ..                ...|..            ..|.|||.|.|. |
KLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYD

HEERITAAEALEHKFF
...||||..||.| .|
PDKRITAEQALQHPYF

Kinase 89154.m00319.AA S_TKc 46-331 24 9.2e-61 209.09 SMART 1-231 (231) Show / Hide
Range on Protein: 46-331
Range on HMM: 1-231/231
Sequence Identity: 24% (74 aa)

FQVISPVGTGKYSTVFLGRMDG-KKKCAIKTLKNVPHFKIQKEICLLTKIKDIPNTVQLYGVVVDPLTDTFSIITDYLKS--ESPRTLFPK---------
.... ..| | ...|...|  . ....||| .|     .|..|| .| |  . || |.||.| .|   | . ....|.     . ...  |         
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK--HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LTLENIRILMWQLLTCLNESHKRGIMHRDVKPGNILFGQNRKSMKLIDWGLGDFYLAKEAYSPRVSTLRYKAPELLLNYQYYDY-GIDVWGAGCVLAEML
..   .| .|.|..  |.  |..||.|||.|| |||. .     |..| ||  ..      .  . |. | |||.|     |..  .|.|  ||.|.|||
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE---HIKICDFGLARQL------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYEML

VRFPFFEGRDIDEMVGDVSSVCGTNAITAYVNKYGLQLTPEMQKNLSNTQTPQFNKLTQNPSFNQAKNDHDALDLLQKLLTVDHEERITAAEALE-----
.. | |.  ....|   .                                                  ...|.|...|.|..| |.|.|| |||.     
CGYPPFP--QMQMMFKKIG-------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDI

--HKFF
  | .|
KCHPWF

Kinase 89154.m00319.AA Ciliate-E2 46-331 17 1.2e-43 147.68 In-house 1-365 (365) Show / Hide
Range on Protein: 46-331
Range on HMM: 1-365/365
Sequence Identity: 17% (75 aa)

FQVISPVGTGKYSTVFLG--RMDGK----------------------KKCAIKTLKNVPHFKIQKEICLLTKIK---------------DIPNTVQLYGV
. .|   |.| ...|...  . ..|                      |. |.|..|.   . | .|| .. .|.               . || ...| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

VVDPLTDTFSIITDYLKSESPRT------LFP--------KLTLENIRILMWQLLT---------------CLNESHKRG-IMHRDVKPGNILFGQNRKS
  .  .... ....|..  . .       ..         ..|.. |. .|.|.|                .|.. |... |.||| || ||||      
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF------

MKLIDWGLGDFYL-----------AKEAYSPR----------------------VSTLRYKAPELLLNYQY--------YDYGIDVWGAGCVLAEMLVR-
 |.||.||  .|            .|.    .                      . |. |.||| | . .|        ||| .|.| .|..| |||   
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

FPFFEGRDIDEMVGDVSSVCGTNAITAYVNKYGLQLTPEMQKNLSNTQTPQFNKLTQ-NPSFNQA-----------------KNDHDALDLLQK----LL
.||                                                ...  | . .|...                 | . .. ||..|    .|
PPF------------------------------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRML

TVDHEERIT-AAEALEHKFF
 .| |.||| . ..|.|..|
QKDPEKRITGWEQILNHPWF

Kinase 89154.m00319.AA CAMK 51-331 15 4.7e-39 122.99 In-house 1-425 (425) Show / Hide
Range on Protein: 51-331
Range on HMM: 1-425/425
Sequence Identity: 15% (71 aa)

PVGTGKYSTVFLGRM-DGK------------KKCAIKTLK-------------------------------NVPHFKIQKEICLLTKIK------DIPNT
  |.| ...|.|..    .            .|.||| ..                                .   ....||... |..      | || 
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLYGVVVDPL---------TDT---------FSIIT---DYLKSESP----------RTLF------------PKLTLENIRILMWQLLTCLNESHKRG
..|| |  ||          | .         . ...   .|                .. .             ..| .  | ...|..  ..  |...
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IMHRDVKPGNILFGQNR----------------KSMKLIDWGLGDFYLAKE------------------------AYSPRVSTLRYKA-PELLLN-----
|.||| || |||. .|                    |.||.|.  ..  .|                         .. .. |. | | ||.|.      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

--------YQYYDYGIDVWGAGCVLAEMLVRFPFFEGRDIDEMVG--DVSSVCGTNAITAYVNKYGLQLTPEMQKNLSNTQTPQFNKLTQNPSFNQAKND
         .||.. .|.| .|..|  ||. .| |.| . .| ..                                 | .    . .. . .|   . .
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEW---------------------------IGMNDYELFEKIMKGKYDFPPPYFS

H-----------------------DALDLLQKLLTVDHEERITAAEALEHKFF
.                       .. ||..|.|.|| |.|.|....|.|...
PISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 89154.m00319.AA Pkinase 46-247 26 6e-37 131.73 Pfam 1-227 (293) Show / Hide
Range on Protein: 46-247
Range on HMM: 1-227/293
Sequence Identity: 26% (63 aa)

FQVISPVGTGKYSTVFLGRMDGKKK-CAIKTLKNVPHFKIQK--------EICLLTKIKDIPNTVQLYGVVVDPLTDTFSIITDYLKS-----ESPRTLF
.......| | ...|....  |  |  |.|..| . | | .|        ||... .. . || |.||... |   |   ....|.       .  . . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRL-NHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYIS

----PKL--TLENIRILMWQLLTCLNESHKRGIMHRDVKPGNILFGQNRKSM----KLIDWGLGDF--YLAKEAYSPRVSTLRYKAPELLLNYQYYDYGI
     ..  . . ..  |.|.|  |.  |..||.|||.|| |||.  |.       |..|.||  .  |  .. .. .. |..| |||... .|||.. .
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILID-NNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVWGAGCVLAEMLVRFPFFEGR------DIDEMV
|.|..||.|.||| . | | |.      | ..|.
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMI

Kinase 89154.m00319.AA CDK 46-256 27 5e-36 112.63 In-house 1-243 (284) Show / Hide
Range on Protein: 46-256
Range on HMM: 1-243/284
Sequence Identity: 27% (70 aa)

FQVISPVGTGKYSTVFLGRMDG------KKKCAIKTLKNVP--------HFKI--QKEICLLTKIKDIPNTVQLYGVVVDPLTD---------TFSIITD
.. .  .| | | .|. .|         .. .|.| ..            | |    ||.|| ..   || |.|. |...  .|         ..... .
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

YLKS------ESPRTLFPKLTLENIRILMWQLLTCLNESHKRGIMHRDVKPGNILFGQNRK----SMKLIDWGLGDFYLA-------KEAYSPRVSTLRY
|.        .             |. .|||||  |.  |...||||| || |||   | .    . |. | ||   .           .|...| || |
YMDHDLKKYMD-------------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWY

KAPELLLNYQYYD--YGIDVWGAGCVLAEMLV---RFPFFEGRDIDEMVGDVSSVCGT
 ||||||  . |.   .||.|..||..|||.    | |.| |.   .    .. .|||
RAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGT

Kinase 89154.m00319.AA Ciliate-E2-Unclassified 46-331 17 1.2e-33 114.1 In-house 1-352 (352) Show / Hide
Range on Protein: 46-331
Range on HMM: 1-352/352
Sequence Identity: 17% (66 aa)

FQVISPVGTGKYSTVFLG-RMDGKKKCAIKTLKNVPHFK----------IQKEICLLTKI---------------KDIPNTVQLYGVVVDPLTDTFSIIT
. .|   |.| ...|..  . . |.. |.|..| . ..|          ..... .  |                ...|. . .. . ..  .... |..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

DYLKSESPRT---LFPK-----------------LTLENIR-----ILMWQLLTCLNESHKRG-IMHRDVKPGNILFGQNRK--SMKLIDWGLGDFYLA-
.|..  . .     ..|                 .| ....      ...|.| .|.  |. . | ||| || |||| .| |    |.||.|.  .|   
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

---------------KEAYSPRVSTLRYK----APELLLNYQYYD---YGIDVWGAGCVLAEMLVRFPFFEGRDIDE-----------MVGDVSSVCGTN
               .. .. .. |..|.    |||.| . .|..   | .|.|. |..| |||   . |.... ..                       
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNA-----------

AITAYVNKYGLQLTPEMQKNLSNTQTPQFNKLTQNPSFNQ----AKNDHDALDLLQ----KLLTVDHEERITAAEALEHKFF
                     .. .  ...| .|.|.|..     . .  | |...    |.| .. ..|||. ..|.| .|
-------------------YRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 89154.m00319.AA CDC2 46-240 28 1.1e-32 97.43 In-house 1-211 (301) Show / Hide
Range on Protein: 46-240
Range on HMM: 1-211/301
Sequence Identity: 28% (62 aa)

FQVISPVGTGKYSTVFLGR-MDGKKKCAIKTLKNVPHFKI-------QKEICLLTKIKDIPNTVQLYGVVVDPLTDTFSIITDYLKSESPRTLF----P-
.| |  .| | |  |. .. |. .. .|.|  .      .        .||..| ..|| || |.|  |..        ....||    .. .     . 
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ---NKLYMVFEYLDMDLKKYMDMSIPKN

-KLTLENIRILMWQLLTCLNESHKRGIMHRDVKPGNILFGQNRKSMKLIDWGLG-DFYLAKEAYSPR--VSTLRYKAPELLLNYQYYDYGIDVWGAGCVL
 ........ .|.|.|  ..  | |.||||| || |||   . .  |. | ||. .|   . .| .   | || | |||.||  ..|. ..|.|  ||..
KHMPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGN-IKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIF

AEM---LVRFPFFEG
|||     . |.| |
AEMFMDVTKKPLFHG

Kinase 89154.m00319.AA Ciliate-E2a 46-245 28 2.4e-24 68.57 In-house 1-223 (275) Show / Hide
Range on Protein: 46-245
Range on HMM: 1-223/275
Sequence Identity: 28% (66 aa)

FQVISPVGTGKYSTVFLG--RMDGKK---KCAIKTLKNVPH---FKIQKEICLLTKIKDIPNTVQLYGVVVDPLTDTFSIITDYLKSESPRTLF------
. .|   |.|..  |.|   . .||.   |  ||   .. .   .....|| .. .. | ||  .||.|  |   ... ....|...   ..|.      
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIK-KMYQQKKGKEYFMNEINIMRQL-DHPNIIKLYEVYED--ENNYYLVMEYCEG---GELYDKIKQC

PKLTLE--NIRILMWQLL-TCLNESHKRGIMHRDVKPGNILFG---QNR---KSMKLIDWGLGDFY--LAKEAYSPRVSTLRYKAPELLLNYQY-----Y
 ... |  .|. .|.|||   |.  |.|.||||| || ||||    .|    .  |.||.||..|.    |.   ... |  | |||.| | .      |
KRFFEEIQEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLATFIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQY

DYGIDVWGAGCVLAEMLVRFPFFEGRDIDE
|.  |.| .|...  .|.  | |.|.. .|
DTKCDMWSCGVIFYILLCGKPPFKGKTYNE

Kinase 89154.m00319.AA RCK 139-240 35 7.6e-21 62.62 In-house 107-216 (298) Show / Hide
Range on Protein: 139-240
Range on HMM: 107-216/298
Sequence Identity: 35% (40 aa)

IRILMWQLLTCLNESHKRGIMHRDVKPGNILFGQ-----NRKSMKLIDWGLGDFYLAKEAYSPR-----VSTLRYKAPELLLNYQYYDYGIDVWGAGCVL
|.  | |.|  |.  || |..|||.|| ||.        . ..  .|   ..|| |..| .|       |||  | |||.||  .||.. .|.|. ||. 
IKNIMYQILQGLAHMHKHGFFHRDLKPENIMCTGSQQYFEDQDQDHI--KIADFGLCREIRSKPPYTDYVSTRWYRAPECLLRCTYYNSPMDIWAVGCIM

AEMLVRFPFFEG
.|  . .| | |
YELYMLRPLFPG

Kinase 89154.m00319.AA CDK9 133-240 39 7.5e-20 64.95 In-house 115-228 (340) Show / Hide
Range on Protein: 133-240
Range on HMM: 115-228/340
Sequence Identity: 39% (45 aa)

KLTLENIRILMWQLLTCLNESHKRGIMHRDVKPGNILFGQNRKSMKLIDWGLG-DFYLAKEAYSPR------VSTLRYKAPELLLNYQYYDYGIDVWGAG
|..|  |. .| .|.  |.  |.  |.||| |  |.|  ..   .|| | ||   | ..|    .|      | || |  |||||    |   ||.||||
KFSLGHIKKMMQHLMNGLYYIHRNKILHRDMKAANVLITKDG-ILKLADFGLARAFSQPKNDAPNRPLYTNRVVTLWYRPPELLLGDRNYGPPIDMWGAG

CVLAEMLVRFPFFEG
|..|||  | |   |
CIMAEMWTRSPIMQG

Kinase 89154.m00319.AA Ciliate-E2a 303-331 44 9.3e-16 42.89 In-house 247-275 (275) Show / Hide
Range on Protein: 303-331
Range on HMM: 247-275/275
Sequence Identity: 44% (13 aa)

DALDLLQKLLTVDHEERITAAEALEHKFF
.. ||..|.| .|...||||..||.|..|
ECKDLMKKMLEKDPKKRITAQQALNHPWF

Kinase 89154.m00319.AA CDK 289-331 34 3.6e-13 38.32 In-house 252-284 (284) Show / Hide
Range on Protein: 289-331
Range on HMM: 252-284/284
Sequence Identity: 34% (15 aa)

LTQNPSFNQAKNDHDALDLLQKLLTVDHEERITAAEALEHKFF
.|. | .          |||.|.|. | . ||.| .||.|..|
VTKLPDY----------DLLNKMLCYDPKKRISAEQALQHPYF

Kinase 89154.m00319.AA RCK 303-331 44 1.8e-12 35.62 In-house 270-298 (298) Show / Hide
Range on Protein: 303-331
Range on HMM: 270-298/298
Sequence Identity: 44% (13 aa)

DALDLLQKLLTVDHEERITAAEALEHKFF
|...|..|.|. | ..||||..||.|..|
DCIELMEKMLQWDPQKRITAQQALQHPYF

Kinase 89154.m00319.AA CDC2 284-331 27 2.6e-12 33.59 In-house 244-301 (301) Show / Hide
Range on Protein: 284-331
Range on HMM: 244-301/301
Sequence Identity: 27% (16 aa)

PQFNKLTQNPSFNQAKN----------DHDALDLLQKLLTVDHEERITAAEALEHKFF
. | .....   .. .|          |....|||...|  | . ||.| |||.|..|
NTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHPYF

Kinase 89154.m00319.AA CDK9 301-331 41 9.6e-12 36.53 In-house 310-340 (340) Show / Hide
Range on Protein: 301-331
Range on HMM: 310-340/340
Sequence Identity: 41% (13 aa)

DHDALDLLQKLLTVDHEERITAAEALEHKFF
| .|..|. |||..| . |....|||.| .|
DQQACHLIDKLLNIDPKKRMDSDEALDHDWF

Kinase 89154.m00319.AA TyrKc 46-331 18 4.7e-09 -76.19 SMART 1-280 (280) Show / Hide
Range on Protein: 46-331
Range on HMM: 1-280/280
Sequence Identity: 18% (62 aa)

FQVISPVGTGKYSTVFLGRMDGKKKCAIKTLKNVPHFKIQKEICLLTKI-KDIPNTVQLYGVVVDPLT-----DTFSIIT---------DYLKSESPRTL
 . .   | | . .|..|...   ..|.|.||.  .  . .|. ...|. .. || |.||||....       .   |..         |||..  |.  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--

FPKLTLENIRILMWQLLTCLNESHKRGIMHRDVKPGNILFGQNRKSMKLIDWGLGDFYLAK-------EAYS------PR-VSTLRYKAPELLLNYQYYD
   |...     .||     .  |.... |||    |.| | |.  .|  | ||  .   .       . |.       . .  .|  ||| . ||  . 
---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH-TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

YGIDVWGAGCVLAEMLVR-FPFFEG-----RDIDEMVGDVSSV----CGTN----AITAYVNKYGLQLTPEMQKNLSNTQTPQFNKLTQNPSFNQAKNDH
   |||  | .. |.. .  .  .|      . .|.. .| .     .  |    .                                    |     | 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------------------F-VCCPDE

DALDLLQKLLTVDHEERITAAEALEHKFF
    . ..    | |.| | .|   |..|
MYQ-IMKQCWHEDPEDRPTFSEI--HECF

Kinase 89154.m00319.AA Pkinase 303-331 31 1.2e-08 31.68 Pfam 265-293 (293) Show / Hide
Range on Protein: 303-331
Range on HMM: 265-293/293
Sequence Identity: 31% (9 aa)

DALDLLQKLLTVDHEERITAAEALEHKFF
...|.. ..|..| ..|.||...|.|..|
ECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 89154.m00319.AA Pkinase_Tyr 46-111 21 6e-06 20.86 Pfam 1-82 (270) Show / Hide
Range on Protein: 46-111
Range on HMM: 1-82/270
Sequence Identity: 21% (18 aa)

FQVISPVGTGKYSTVFLGRMD-----GKKKCAIKTLKNVPHFK------IQKEICLLTKIKDIPNTVQLYGVVV---DP--L
 . .   | | . .|..|...     .| ..|.|.||.  . .        .|. ..... . || |.||||..   .|  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQI

Kinase 89154.m00319.AA RCK 46-78 29 0.000303 9.05 In-house 1-34 (298) Show / Hide
Range on Protein: 46-78
Range on HMM: 1-34/298
Sequence Identity: 29% (10 aa)

FQVISPVGTGKYSTVFLG-RMDGKKKCAIKTLKN
 |.|. .| | |..|... . . ... |||..|.
YQIIKQLGDGTYGCVMKAQNKETGEIVAIKKMKQ