Gene 83399.m00070 (T.vaginalis)

83399.m00070

Species: T.vaginalis
Alias: 83399.m00070, TvagK0728
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: CDC15

Sequence

Name Sequence Type Origin Length Description Download
83399.m00070.AA Protein None 1308 None Fasta, JSON
83399.m00070.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 83399.m00070.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 83399.m00070.AA Dicty2 40-290 48 4.3e-110 372.05 In-house 1-264 (264) Show / Hide 
Range on Protein: 40-290
Range on HMM: 1-264/264
Sequence Identity: 48% (127 aa)

FQLG-PKLGRGAFGCVYQGLNKDTGDYVAIKTIS----LTRFP-DALDSVQQEIDLMAPLEHPNVVKYITSHQTKDFLYIVMEFAEGGSLQNVQKKFENF
.|.|  |.|.|||| ||.||.. ||| |||| |.    .|  . . . |. |||.|   | |.| |||| . .|.. |||..|. |.|||  . |||  |
YQIGDEKIGKGAFGTVYKGLHIETGDFVAIKQINIMKKKTKISEEQHQSIMQEIHLLKKLNHHNIVKYIEHIETENHLYIILEYIENGSLSKIIKKFGCF

NEHLASKYLYEVLLGLKYLHEQSIIHRDIKAANILLTK-GH---CKLSDFGISVKLT-DNKNPDALSQCSPFWAAPEVISMEP--ITEKCDIWSLGITAI
 | | . |.| || || |||.| .||||||||||| || |     ||.|||   ..  .  ....     |.| ||||| |    .. .||||||| | |
PESLCCIYIYQVLKGLVYLHRQGVIHRDIKAANILITKEGKSGVIKLADFGVATHIDYSDDDSRYTVVGTPYWMAPEVIQMSGNHCCTACDIWSLGCTII

ELFAGQPPYFELNAVRAMFQIVQNPEPPLPKDISANFKDFLTSCLTKNVTFRKNTEQLLKHPFI
||. | |||. ||   ||| .||.. ||||.|||. .||||  |  |  . |    |||.|| |
ELLTGNPPYWDLNPMHAMFRMVQDDHPPLPNDISPECKDFLMQCFCKDPNQRMTAKQLLHHPWI
Kinase 83399.m00070.AA STE 40-290 29 1.9e-105 356.61 In-house 1-359 (359) Show / Hide 
Range on Protein: 40-290
Range on HMM: 1-359/359
Sequence Identity: 29% (108 aa)

FQLGPKLGRGAFGCVYQGLNKD---------------TGDYVAIKTIS----------------LTRFPDALDSVQQEIDLMAPLE--HPNVVKYITSHQ
...  |.|.|||| ||...|..               ||...||| ..                 ..... ......||..|  .   |||.|||. .. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

TK-------DFLYIVMEFAEGGSLQ----NVQKKFENFN----------EHLASKYLYEVLLG-LKYLHEQSIIHRDIKAANILLTKGHCKLSDFGISVK
 .       | |.|.||. .||||     .. ......|          |.. .......| | |.|||.. |||||||.|||||    .||.|||.. .
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL----VKLCDFGVCGQ

LTDN-----------------KNPDALSQCSPFWAAPEVISM------EPITEKCDIWSLGITAIELFAGQPPYFELNAVRAMFQIVQN-----------
|||.                 .. . .  .   | |||||.        . ..||||||||.|.||.  |.||.....  ||||.| .|           
LTDSMANIQSNNIIDCIETMQQKRNTFVGTP--WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----PEPPLPKDIS-------------------ANFKDFLTSCLTKNVTFRKNTEQLLK--HPFI
    | |||| ..|                    .||||.  ||.|.   | ...||||  ||||
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 83399.m00070.AA STE20 40-290 42 2.4e-99 336.33 In-house 1-288 (288) Show / Hide 
Range on Protein: 40-290
Range on HMM: 1-288/288
Sequence Identity: 42% (121 aa)

FQLGPKLGRGAFGCVYQGLNKDTGDY----VAIKTISLTRFP---DALDSVQQEIDLMAPLEHPNVVKYITSHQTK----DFLYIVMEFAEGGSLQNVQK
..|  |.|.|..| || . .|.||.|    |||| ..|       | ....|.||. |. . |||.|||..|.. .    | |.||||. .||||. . |
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---KFEN------FNEHLASKYLYEVLLGLKYLHEQSIIHRDIKAANILLTKG-HCKLSDFGISVKLTD----NKN-PDALSQCSPFWAAPEVISM----
   | ..      .||   .  ..||| ||.|||.. ||||||||.|||||.   .||.||| . .||.     .. .      .|.| |||||.     
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEGP

-EPITEKCDIWSLGITAIELFAGQPPYFELNAVRAMFQIV--QNPEPPLPK----DISANFKDFLTSCLTKNVTFRKNTEQLLKHPFI
  . ..|||||||||||||.  |.||||.....||||.|   ||| |.| .      | .|.||. .||.|.. .|  ..||||||||
DKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 83399.m00070.AA YSK 40-290 40 1.1e-91 276.27 In-house 1-257 (257) Show / Hide 
Range on Protein: 40-290
Range on HMM: 1-257/257
Sequence Identity: 40% (105 aa)

FQLGPKLGRGAFGCVYQGLNKDTGDYVAIKTISLTRFPDALDSVQQEIDLMAPLEHPNVVKYITSHQTKDFLYIVMEFAEGGSLQNVQKK--FENFNEHL
|    . ||| || || | .. |.  ||||.| |    |  . .||||   . .. |.. ||. |      | |.||.  |||.    |.     | |  
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIEDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQFDEKY

ASKYLYEVLLGLKYLHEQSIIHRDIKAANILLTK-GHCKLSDFGISVKLTDNKNPDALSQCSPFWAAPEVISM--EPITEKCDIWSLGITAIELFAGQPP
 .  | |.|.||.|||..  |||||||||.||.. |  || |||.. ..||.         .|.| |||||        .| |||||||||.|.  |.||
IAIILREILKGLDYLHSERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTFVGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMAKGEPP

YFELNAVRAMFQIVQNPEPPLPK-DISANFKDFLTSCLTKNVTFRKNTEQLLKHPFI
| .. . |.|| |. |. | | . . | .||.|   || |.  .|   ..|||| ||
YCDYHPMRVMFLIPKNNPPKLEGRSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase 83399.m00070.AA S_TKc 40-290 32 3.1e-91 310.32 SMART 1-231 (231) Show / Hide 
Range on Protein: 40-290
Range on HMM: 1-231/231
Sequence Identity: 32% (87 aa)

FQLGPKLGRGAFGCVYQGLNKDTGDYVAIKTISLTRFPDALDSVQQEIDLMAPLEHPNVVKYITSHQTKDFLYIVMEFAEG--GSLQNVQKKFEN-----
.... |.|.||||.||.. .|.|| .|||| |.        .....||...    |||.||.. . |. |.||.|||...|  |.|  . ||        
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-FNEHLASKYLYEVLLGLKYLHEQSIIHRDIKAANILLTKGHCKLSDFGISVKLTDNKNPDALSQCSPFWAAPEVISMEPITE-KCDIWSLGITAIELFA
 |.|  | .|.|.....|.|.|.. |||||.| .||||.. | |..|||.. .|            .|.. ||||.   . .  |||.||.|.. .|...
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GQPPYFELNAVRAMFQIVQNPEPPLPKDISANFKDFLTSCLTKNVTFRKNTEQLLK-------HPFI
|.||.     . .||...           |  .|||.  ||.|. . |    ..|.       ||..
GYPPFP---QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 83399.m00070.AA STE11 40-290 35 7.5e-86 291.52 In-house 1-303 (303) Show / Hide 
Range on Protein: 40-290
Range on HMM: 1-303/303
Sequence Identity: 35% (108 aa)

FQLGPKLGRGAFGCVYQGLNKDTGDYVAIKTISLTRFP-------DALDS------VQQEIDLMAPLEHPNVVKYITSHQ---TKDFLYIVMEFAEGGSL
.|.| ..|.|||| ||...|.|||  .|.| | . .         . ..|       |.|| ||  | |.| |.|. . .    .|...| ||. .||||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSL

QNVQK-KFEN--FNEHLASKYLYEVLLGLKYLHEQSIIHRDIKAANILLTK-GH-CKLSDFGISVKLTDNKNPDAL----------SQCSPF--------
  . . |.    |.|.. .||   .| ||.|||.. |||||||.||||| . |. |||.|||....|  . .  .            . .|.        
SSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPM

WAAPEVISMEP---ITEKCDIWSLGITAIELFAGQPPYFELNA--VRAMFQIV-Q-NPEPPLPKDIS------ANFKDFLTSCLTKNVTFRKNTEQLLKH
| |||||. |.    . |.|||||| | || . |.||. ....    ||| |. . .| ||.| ..|      .. .|||  |....   | .  |||.|
WMAPEVIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQH

PFI
|||
PFI
Kinase 83399.m00070.AA Pkinase 40-290 32 2.5e-83 287.91 Pfam 1-293 (293) Show / Hide 
Range on Protein: 40-290
Range on HMM: 1-293/293
Sequence Identity: 32% (96 aa)

FQLGPKLGRGAFGCVYQGLNKDTGDYVAIKTISLTRFPDALDSVQQ---EIDLMAPLEHPNVVKYITSHQTKDFLYIVMEFAEGG----SLQ-----NVQ
...| |.|.|.|||||.. .|.||. ||.|.|.. .  .  |       || .|. | |||.|... . ..|| .|.|||..|||    .|        .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

KKFENFNEHLASKYLYEVLLGLKYLHEQSIIHRDIKAANILLT-KGHC----KLSDFGISVKLTDNKNPDALSQC-SPFWAAPEVIS-MEPITEKCDIWS
..|  | |. . .|.|..| ||.|.|...|||||.| .|||.  .||.    |..|||.. ..   .|. . . | .|...|||||   .... |.|.||
GCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

LGITAIELFAGQPPYFEL----NAVRAMFQIVQNPEPPLPKDIS-----------------------ANFKDFLTSCLTKNVTFRKNTEQLLKHPFI
.|.. .|.. |.||. .     | .. |. |... .|||. |..                        ..|||...||.|. . | . ||.|.||..
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 83399.m00070.AA STE11-Unclassified 40-290 32 5e-78 265.53 In-house 1-308 (308) Show / Hide 
Range on Protein: 40-290
Range on HMM: 1-308/308
Sequence Identity: 32% (100 aa)

FQLGPKLGRGAFGCVYQGLNKDTGDYVAIKTISL-------TRFPDA-LDSVQQEIDLMAPLEHPNVVKYITSH--QTKDFLYIVMEFAEGGSLQNVQKK
.| |  .|.|.|| ||...|..||  .|.|.|           . .  ..| |.|. ..  |.|.| |.|.     . .|...|.||  .|||.    .|
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKNIVQYYGCEIHKHEDCINIFMEYMPGGSIWSMLNK

FENFNEHLASKYLYEVLLGLKYLHEQSIIHRDIKAANILL-TKGHCKLSDFGISV---------------------KLT----DNKNPDALSQCSPF---
.  |.| ...||  ..| ||.|||...|||||||.||||. ..| |||.|||..                      |..    ...| ... | .|.   
YGCFDEMVIKKYTKQILEGLAYLHSHGIIHRDIKGANILIDFDGICKLTDFGCAKQIEFDRTRTVRMNKIQNFDHYKICQHINSQQNHCKSMQGTPYQPF

WAAPEVIS---MEPITEKCDIWSLGITAIELFAGQPPYFELNA---VRAMFQIV-QNPEPPLPKDIS-----------ANFKDFLTSCLTKNVTFRKNTE
| |||||.    .  . | |||||| | || ..|..|.  ...   . |.. ||  |  |..| . |           .  ||||  |.. .   | .. 
WMAPEVIKNSTQTGHCRKSDIWSLGCTVIEMATGKHPWSNCQNDNFMWAIMKIVMSNQIPQIPEHLSPVCDFISCWISQECKDFLRKCFQIDPKKRPTAN

QLLKHPFI
|||.||||
QLLQHPFI
Kinase 83399.m00070.AA MST 40-290 43 6.3e-76 240.8 In-house 1-254 (254) Show / Hide 
Range on Protein: 40-290
Range on HMM: 1-254/254
Sequence Identity: 43% (111 aa)

FQLGPKLGRGAFGCVYQGLNKDTGDYVAIKTISLTRFPDALDSVQQEIDLMAPLEHPNVVKYITSHQ--TKDFLYIVMEFAEGGSLQNVQKKFE-NFNEH
| .  |||.|..| ||. ..| || .|||| ..       |..   ||  |     ...|||  |        . ||||. ..||.  . |     .|| 
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPV---NEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNEQ

LASKYLYEVLLGLKYLHEQSIIHRDIKAANILL-TKGHCKLSDFGISVKLTD-NKNPDALSQCSPFWAAPEVISMEPITEKCDIWSLGITAIELFAGQPP
  .  || .|.||.|||  ..|||||||.|||| ..|.|||.||| |  ||| .   . .   .|.| |||||     . | |||||||||||.  | ||
QIACILYDTLQGLQYLHDNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTV-IGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGMPP

YFELNAVRAMFQIVQNPEPPL--PKDISANFKDFLTSCLTKNVTFRKNTEQLLKHPFI
|... ..|||| | |.| | .  |   | .| ||. .||.||   |.  ||||.||||
YSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 83399.m00070.AA PAKA 40-290 38 3.1e-70 239.66 In-house 1-260 (260) Show / Hide 
Range on Protein: 40-290
Range on HMM: 1-260/260
Sequence Identity: 38% (100 aa)

FQLGPKLGRGAFGCVYQGLNKDTGDY--VAIKTISLTRFPDALDSVQQEIDLMAPLEHPNVVKYITSHQTKDFLYIVMEFAEGGSLQNVQKKFEN-----
..   |.| || | || . |. |..   ||||.. .   ..  . .  || .|    |.|.|.|| |.  .| |..|||. |||.|  | ....|     
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKN-QPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCNY

FNEHLASKYLYEVLLGLKYLHEQSIIHRDIKAANILL-TKGHCKLSDFGISVKLTDNKNPDALSQCSPFWAAPEVISMEPITEKCDIWSLGITAIELFAG
..|  ..  . |.| ||...|....||||||  |||| . |  |. |||  . ||. .   .     | | |||||.     || ||||||| |||.  |
MDEGQIAYVCRECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMIEG

QPPYFELNAVRAMFQIVQN--PEPPLPKDISANFKDFLTSCLTKNVTFRKNTEQLLKHPFI
.||| . . .|||. | .|  |.   |   | .|.|||  || ..|  |  ...||.|||.
EPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 83399.m00070.AA CAMK 45-290 18 7.3e-69 220.78 In-house 1-425 (425) Show / Hide 
Range on Protein: 45-290
Range on HMM: 1-425/425
Sequence Identity: 18% (79 aa)

KLGRGAFGCVYQGLNKDTG------------DYVAIKTISLTRFPD---------------------------ALDSVQQEIDLMAP-------LEHPNV
.||||.|| |. . .| |.              |||| |. .. .|                            ...|..||..|         | |||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKYIT---------------SHQT-----KDFLYIVM---EFAEGG----SLQNVQKKFEN---------------FNEHLASKYLYEVLLGLKYLHEQS
.| .                . ..     ....|.||   |...||     | .  .. ..               |.|. |..|   .. ...|.|.. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

IIHRDIKAANILLTK------------------GHCKLSDFGISVKLTDNKNPDAL-----------------------SQCSPFWAA-PEVISM-----
|.|||.|  ||||..                  .  |..||| . |.....|   .                       .  .|  .| |||..      
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------EPITEKCDIWSLGITAIELFAGQPPYFE------------LNAVRAMFQIVQNPEPP-LPKD---------------ISAN--------FK
         .....|||.||.|.    .  | ||. .             .  . .|. ... .    |.                || .         |
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

DFLTSCLTKNVTFRKNTEQLLKHPFI
|.. ..|... . | . || |.||..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 83399.m00070.AA ULK 40-290 26 3e-67 229.72 In-house 1-329 (329) Show / Hide 
Range on Protein: 40-290
Range on HMM: 1-329/329
Sequence Identity: 26% (88 aa)

FQLGPKLGRGAFGCVYQGLNKDT----GDYVAIKTIS---LTRFPDA------LDSVQQEIDLMAPLE--------HPNVVKYITSHQTKDF--LYIVME
..|  .|| |.|| ||.| ||.|    . .||.| |.   . ....       ......||..|  |         |||.||..   .|...  .||.||
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

FAEGGSLQNVQKKFEN----------FNEHLASKYLYEVLLGLKYLHEQSIIHRDIKAANILLTKG-------------HCKLSDFGISVKLTDN-KNPD
. .|| |..  ||  .          ..|  | ....  | |.|.||.. ||||||| .|||...|             ..|..||| . ..... .. .
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

ALSQCS--------PFWAAPEVIS----MEPIT-EKCDIWSLGITAIELFAGQPPYFE-LNAVR-----AMFQI-------VQNPEPPLPKD-----ISA
 .  |.        |   ||....     .| .  ||||||||.   |.  |.||...  |          ...       ...  .  |||     || 
MMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISP

NFKDFLTSCLTKNVTFRKNTEQLLKHPFI
..||..  .|... . | . |.|..||..
ECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase 83399.m00070.AA Pkinase_Tyr 40-247 27 1.1e-33 114.66 Pfam 1-228 (270) Show / Hide 
Range on Protein: 40-247
Range on HMM: 1-228/270
Sequence Identity: 27% (64 aa)

FQLGPKLGRGAFGCVYQGLNK----DTGDYVAIKTISLTRFPDA---LDSVQQEIDLMAPL-EHPNVVKYITSHQ-TKDF--LYIVMEFAEGGSLQN-VQ
 ..| |||.|||| ||.|  |    .|.  ||.|..      .    ...  .|. .|  |  |||.|...      ..   .|||||....|.| .  .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KK---FENFNEHLASKYLYEVLLGLKYLHEQSIIHRDIKAANILLT-KGHCKLSDFGISVKL--TDNK-NPDALSQCSPFWAAPEVISMEPITEKCDIWS
|.    .... .   .. ...  |. ||... .||||. | |.|.| ....| .||| .  .  .|.       . .  .| |||.|.    |.| |.||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

LGITAIELFA-GQPP-YFELNAVRAMFQI
 |..  |.|  |. | | ..   . . .|
FGVLMWEIFTYGEQPTYPGMSNEEVYEYI
Kinase 83399.m00070.AA TyrKc 40-290 25 5.2e-28 100.29 SMART 1-280 (280) Show / Hide 
Range on Protein: 40-290
Range on HMM: 1-280/280
Sequence Identity: 25% (74 aa)

FQLGPKLGRGAFGCVYQGLNKDTGDYVAIKTISLTRFPDALDSVQQEIDLMAPL--EHPNVVKYITSHQTK-------DFLYIVMEFAEGGSLQNVQKKF
 .|| |||.|||| ||.|  |     ||.|..        .    .|. .|  |  .|||.|. .    ..       . |.||||....|.|..  .| 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

EN-FNEHLASKYLYEVLLGLKYLHEQSIIHRDIKAANILLTKGH-CKLSDFGISVKLTDN----KNPDALSQ----CSP-----FWAAPEVISMEPI-TE
.. ..     .. . .  |  |||.. .||||. | |.|....| .| |||| | ...|      . |  ..    ..       | |||.| .. . |.
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFTT

KCDIWSLGITAIELFA-GQPPYFE-----LNAVRAMFQIVQNPEPPLPKD--------ISANFKDFLTSCLTKNVTFRKNTEQLLKHPFI
| |.|| |..  |.|  ||.|| .     ... ... .. |   .| |..         ..   .  ..|   .   | . ...  | ..
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF