Gene 95240.m00211 (T.vaginalis)

95240.m00211

Species: T.vaginalis
Alias: TvagK0433, 95240.m00211
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
95240.m00211.AA Protein None 445 None Fasta, JSON
95240.m00211.kin_dom Protein Kinase Domain None 258 None Fasta, JSON

Protein domain

Protein domains of 95240.m00211.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 95240.m00211.AA PH 8-104 34 8.4e-22 79.68 SMART 1-82 (82) Show / Hide 
Range on Protein: 8-104
Range on HMM: 1-82/82
Sequence Identity: 34% (33 aa)

VVKTGWLTKQGGFIKSWRKRWFVLLGRTLYYYTEPGKKESGRIFVDQATAVEKAPEVSRQPAFKIVVPRQRTYYIVGDKQEEVDEWISTLQIAMKGA
|.| |||.|..    .|.|||||| ...|||| ..  | .|.|... .| .| .       .|.|.   . |||.  . .|| .||.. .| |.. .
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK--KPKGSIPLSDCTVRE-P-------CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN
PH 95240.m00211.AA PH 8-102 38 1.4e-20 76.83 Pfam 1-92 (92) Show / Hide 
Range on Protein: 8-102
Range on HMM: 1-92/92
Sequence Identity: 38% (37 aa)

VVKTGWLTKQGGFIKSWRKRWFVLLGRTLYYYTEPGKKESGRIFVDQATAVEKAPEVSRQPAFKIVVPRQRTYYIVGDKQEEVDEWISTLQIAMK
|.| |||.|.| ..|||.|||||| ...|||| .....  | | .. .  |.|.|.  |.  |.|.   .||||.  . .|| ..|.. .| |..
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDKYRPKGSIPLSDC-QVTKVPDNKRPHCFQIRT-DRRTYYFQAESEEEMNDWMQAIQSACR
Kinase 95240.m00211.AA AGC 117-374 33 3.2e-185 484.09 In-house 1-395 (395) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-395/395
Sequence Identity: 33% (135 aa)

FQILSVLGRGTYGKVQLVKYK------KTGQIFAMKSMSKRL-LEEFD--QIEQILTE------------KNVLLKST----------FPFLVS-AHFTF
|..| |.|.|..||| ||. |       ||...||| ..|.    . .  ..|...||            .|.| |             ||.|.  |..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QNEDK--IFMVIDYVP---------GG-ELFSRLK---EEQKFSENRARLYAAE-------IALGLGHLHS-LGFVYRD-LKPENILVDENGHLKITDFG
|..|.  ...| .|.|         || |||..|.    |..|.|.||| ||||       |.|.| .||| .|...|| ||||||| ||.||.|.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LAKGKMGTN--------------------------------------------------TTTSTFCG--TPEYIAPEILQQFPYTKAVDWWS--FGILLF
|.|  |. .                                                   .|.||||  ||||.|||||    |.||.||||  .|.|..
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EMLTGLPPFYDENMT----------KMYRSII------NDPISYP----------PYLSPNACSLLSKLLERDPNLRLGGGDRD-----FEEIKEHPFF
|||||.||||..|            .|. .|.      |... .|          ...||.| .|..|||..||. ||| |..|     .||||.||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 95240.m00211.AA Akt 117-374 48 1.6e-151 487.72 In-house 1-264 (264) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-264/264
Sequence Identity: 48% (129 aa)

FQILSVLGRGTYGKVQLVKYKKTGQIF-AMKSMSKRLLEEFDQIEQILTEKNVLLKSTFPFLVSAHFTFQNEDKIFMVIDYVPGGELFSRLKEEQKFSEN
|..| |||.|..||| ||| |.|.... |||. .|. ... .|.|...||.|.| .  .||.|. |. ||..||...| ||..|||||. |. ...|||.
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

RARLYAAEIALGLGHLHSLGFVYRD-LKPENILVDENGHLKITDFGLAKGK-MGTNTTTSTFCGTPEYIAPEILQQFPYTKAVDWWS-FGILLFEMLTGL
||| |.||| |...|||| . .||| |||||||.|..||...|||||.|   .  . .| ||||||||.|||||..  .|||||||. .|....||..|.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFYDENMTKMYRSIINDPISYP--PYLSPNACSLLSKLLERDPNLRLGGGDRDFEEIKEHPFF
||||...  .|.  | | |. .|  ...||.. .|.|.||..||..|||||  | .|||.||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 95240.m00211.AA SGK 117-374 46 3.4e-143 445.3 In-house 1-283 (283) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-283/283
Sequence Identity: 46% (131 aa)

FQILSVLGRGTYGKVQLVKYKKT------------------GQIFAMKSMSKRLLE-------EFDQIEQILTEKNVLLKS-TFPFLVSAHFTFQNEDKI
|..|.|.| | .||| .|| |..                  ....|||  .|              .   |..|.||.||    ||.|. |. ||...| 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FMVIDYVPGGELFSRLKEEQKFSENRARLYAAEIALGLGHLHSLGFVYRDLKPENILVDENGHLKITDFGLAKGKMGTNTTTSTFCGTPEYIAPEILQQF
..| ||| |||.|. |. |..|.| ||| |||||.. |..|||.  .|||||||||| |  ||...|||||.| .. ||.||.|||||||| |||.|.  
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

PYTKAVDWWSFGILLFEMLTGLPPFYDENMTKMYRSIINDPISYPPYLSPNACSLLSKLLERDPNLRLGGGDRDFEEIKEHPFF
|. ..||||. |..|.||..||||||. |   ||  ||| |.  ||. |. |..|.  ||..||  || |  |||.|||.||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRL-GTKRDFMEIKNHPFF
Kinase 95240.m00211.AA AktR 117-374 45 8.9e-132 444.08 In-house 1-268 (268) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-268/268
Sequence Identity: 45% (121 aa)

FQILSVLGRGTYGKVQLVKYK-KTGQIFAMKSMSKRLLEEFDQIEQILTEKNVLL-KSTFPFLVSAHFTFQNEDKIFMVIDYVPGGELFSRLKEEQKFSE
|... .||.|..||| ||. | ......|||. .|  ..|  |.....||.|..  .. .||.|  |..||...|.| ...|.||||||. || ..||||
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

NRARLYAAEIALGLGHLHSL-GFVYRDLKPENILVDENGHLKITDFGLAK--GKMGTNTTTSTFCGTPEYIAPEILQQ-FPYTKAVDWWSFGILLFEMLT
..|| |.|.| |.| .||.    .|||||||||| ||.||.|||||||.|  ..|  . .. .|||||||.|||.... ....|.||||.|||...||.|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GLPPFYDENMTKMYRSIINDP---ISYPPYLSPNACSLLS-KLLERDPNLRLGGGDRDFEEIKEHPFF
|.||||..| . |. .|.. .   . ||.|.|... .|.  ||| ..|| ||| .. ..||||.||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 95240.m00211.AA PKA 117-374 44 3.2e-121 409.04 In-house 1-263 (263) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-263/263
Sequence Identity: 44% (119 aa)

FQILSVLGRGTYGKVQLVKYKKTGQIFAMKSMSKRLLEEFDQIEQILTEKNVLLKSTFPFLV-SAHFTFQNEDKIFMVIDYVPGGELFSRLKEEQKFSEN
|.|. .||.|..|.|.|.. |..|...||| ..|.      |.| ...|||.|.  ..||.| .  .|||......|| .||||||.||.|  ...||. 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

RARLYAA-EIALGLGHLHSLGFVYRDLKPENILVDENGHLKITDFGLAKGKMGTNTTTSTFCGTPEYIAPEILQQF-PYTKAVDWWSFGILLFEMLTGLP
 |..||| .| | |  |||.  .|||||||||| |.|||.|||||| || |. .   |.| ||||||.||||.|   .. |.||||..||| .|||.| |
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAK-KVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYP

PFYDE--NMTKMYRSIINDPISYPPYLSPNA---CSLLSKLLERDPNLRLGGGDRDFEEIKEHPFF
||||.  .  ..|. |.|  | .|......|    .|..|||..|.. |.|  . . . ||.|..|
PFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 95240.m00211.AA PKC 117-374 45 3.1e-118 384.88 In-house 1-262 (262) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-262/262
Sequence Identity: 45% (118 aa)

FQILSVLGRGTYGKVQLVKYKKTGQIFAMKSMSKRLLEEFDQIEQILTEKNVL-LKSTFPFLVSAHFTFQNEDKIFMVIDYVPGGELFSRLKEEQKFSEN
|. | |||.| .||| |.. |.| ...|.| . | .  . | .|  .||| || | .  |||.. | .|| .|..| |. || || |     . ..|.| 
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

RARLYAAEIALGLGHLHSLGFVYRDLKPENILVDENGHLKITDFGLAKGKMGTNTTTSTFCGTPEYIAPEILQQFPYTKAVDWWSFGILLFEMLTGLPPF
.|| |||||...|  ||. | .||||| .|.|.|. || ||.|||..|  |   .|||||||||.||||||||  .|.|.||||.||.|..||. | .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

YDENMTKMYRSIINDPISYPPYLSPNACSLLSKLLERDPNLRLGGGDRD---FEEIKEHPFF
  |. . . .|| .| ..|| .||  | |.........|. ||| . ..   ...|.|||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 95240.m00211.AA RSK 120-374 44 1.2e-112 380.49 In-house 1-278 (278) Show / Hide 
Range on Protein: 120-374
Range on HMM: 1-278/278
Sequence Identity: 44% (123 aa)

LSVLGRGTYGKVQLVKYK---KTGQIFAMKSMSKRLLEEFDQ-IEQILTEKNVLLKST-FPFLVSAHFTFQNEDKIFMVIDYVPGGELFSRLKEEQK---
|.|||.| |||| |.. .   .||||.|||  .|. .   .  ..  .|| |.|. ..  ||.|. | .|| |.|.... .|..||||| .|..|.    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSENRARLYAAEIALGLGHLHSLGFVYRDLKPENILVDE---NGHLKITDFGLAKG-KMGTNTTTSTFCGTPEYIAPEILQ---QFP-YTKAVDWWSFGI
|||..|. |.|||.| . |||..|...||||||||| |.   .||.|.||||..|  .   |  | |||.| ||.|||.|    |   ..||.||||.|.
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LLFEMLTGLPPFYD---ENMTKMYRSIINDP--ISYP--PYLSPNACSLLSKLLERDPNLRLGGGDRDFEEIKEHPFF
|..||||| |||.    .|  .  . | .     . |  .|||..| .|..|.|.|||. |||.| .| ||||.||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 95240.m00211.AA S_TKc 117-374 38 1.3e-106 361.46 SMART 1-231 (231) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-231/231
Sequence Identity: 38% (103 aa)

FQILSVLGRGTYGKVQLVKYKKTGQIFAMKSMSKRLLEEFDQIEQILTEKNVLLKSTFPFLVSAHFTFQNEDKIFMVIDYVPG--GELFSRLKEEQK---
..|| ..|.|..||| ... ||||.|.|.| ..          |.|. | ..| |   |..|  . .||. |...|| .|..|  |.||...|. ..   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSENRARLYAAEIALGLGHLHSLGFVYRDLKPENILVDENGHLKITDFGLAKGKMGTNTTTSTFCGTPEYIAPEILQQFPYTK-AVDWWSFGILLFE
   |.| .|| |...|...| ..||.|...|||||||||.||  |.||.|||||.         .||||||.|.|||.|   .|.| ..||||.|..|.|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

MLTGLPPFYDENMTKMYRSIINDPISYPPYLSPNACSLLSKLLERDPNLRLGGGDRDF--EEIKEHPFF
||.| |||.  .| .|.. |           || |.....|.|..||. |..  .     ..|| ||.|
MLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95240.m00211.AA RSK-Unclassified 117-374 36 6.6e-103 324.12 In-house 1-283 (283) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-283/283
Sequence Identity: 36% (104 aa)

FQILSVLGRGTYGKVQLVKYKKTGQIFAMKSMSKRLLEEFDQIEQILTEKNVLLKSTFPFLVSAHFTFQNEDKIFMVIDYVPGGELFSRLK--EEQKFSE
|     .|.|  ||| ||. |.| ||.||| ..|  .     |  ..||.|..  .  || |   . || .|. .....| .||..|  |    | .|.|
FIKHRLIGQGDFGKVYLVRKKDTQQIYAMKVLHKHKMIRHNKIKYVMTEQNIMATTNHPFIVTLYHSFQTQDYLYLCMEYCMGGDFFRHLQTRKEKCFCE

NRARLYAAEIALGLGHLHSLGFVYRDLKPENILVDENGHLKITDFGLAKGK---------------------MGTNTTTSTFCGTPEYIAPEILQQFPYT
...| ||.|. . | .|| ..|.||||||.||. .  || . |||.| .                       .   . |  |||| ||.|||...    |
DDVRFYASEVTAALEYLHKRDFIYRDLKPDNIVLHQEGHVMLTDFDLSIQAKDSKKPVMKGSAQSTYVDTKICDHGFRTNSFCGTEEYLAPEMIRRCGHT

KAVDWWSFGILLFEMLTGLPPFYDENMTKMYRSIINDPISYP--PYLSPNACSLLSKLLERDPNLRLGGGDRDFEEIKEHPFF
||||||  ||...||| |.||.| .|   ..  |   ... |   |.| |. .|. |||.| |  ||| .  | ..|| ||||
KAVDWWTLGIVMYEMLFGCPPYYGNNKNETFYNIEKNHVKFPHDSYISNNCRDLIKKLLQRNPAKRLGCKMGDADDIKRHPFF
Kinase 95240.m00211.AA RSK 117-374 39 2e-98 333.32 In-house 1-271 (271) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-271/271
Sequence Identity: 39% (107 aa)

FQILSVLGRGTYGKVQLVKYK---KTGQIFAMKSMSKRLLEEFDQIEQILTEKNVLLKSTFPFLVSAHFTFQNEDKIFMVIDYVPGGELFSRLKEEQKFS
. .....|.|...|| ..| .    |.| .|||   |  .   |.  .  .| ..|  .  || |  |  || | |..|. |   ||.|| ||  .  ||
YELHECIGQGSFSKVYVCKKCQHKDTNQHYAMKIIKKATRDVKDR-VCWEEERIILRYGHHPFIVKLHYVFQDEGKVYMIMDFMRGGDLFDRLLKQKMFS

ENRARLYAAEIALGLGHLHSLGFVYRDLKPENILVDEN----GHLKITDFGLAKGKMGTNTTTSTFCGTPEYIAPEILQQFPYTKAVDWWSFGILLFEML
|. .. |.||||| . .|||.| |.|||||||||.|.     ||.||.|||.||   . |  . |||.| .|.|||.| .  ...|.||||||.|..|||
EREVKFYMAEIALAMEYLHSQGIVHRDLKPENILYDDESGNPGHIKICDFGFAKQLRDENGMLMTFCYTANYMAPEVLKRQGHDQACDWWSFGVLMYEML

TGLPPFYDENMTKMYRSIINDPISY-------PPYLSPNACSLLSKLLERDPNLRLGGGDRDFEEIKEHPFF
|| .||.  .   .   | . .          . ..|. | .||...|.|||. ||| |  . |.||.||.|
TGCTPFQNKPRDTPMNIIQRIKLGMFSMTHGNWDFISDEAKDLLRMMLHRDPHNRLGAGPNGVEQIKQHPWF
Kinase 95240.m00211.AA Pkinase 117-374 31 2.8e-95 327.64 Pfam 1-293 (293) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-293/293
Sequence Identity: 31% (94 aa)

FQILSVLGRGTYGKVQLVKYKKTGQIFAMKSMSKRLLEEFDQIEQIL-TEKNVLLKSTFPFLVSAHFTFQNEDKIFMVIDYVPGG----ELFSRLK--EE
..|....|.|..|.| . . |.||.|.|.| ..||  ..  ... .. .|  ....   |. |  . .|...|.| || .|..||    .||....  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

QKF--SENRARLYAAEIALGLGHLHSLGFVYRDLKPENILVDENGHL----KITDFGLAKGK-MGTNTTTSTFCGTPEYIAPEILQ-QFPYTKAVDWWSF
 .|  ||. .. |. .|. || ..|| |...|||||||||.|.|||.    ||.|||||| .    |. ..||||||.|.|||... . .|...||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILLFEMLTGLPPFYDE------NMTKMYRSIINDPISYPPYLS---------------------PNACSLLSKLLERDPNLRLGGGDRDFEEIKEHPFF
|..|.|||.| |||...      .. .|.. |   |.... . .                     ..........|..||. |..     .|.|..||.|
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-----AEQILQHPWF
Kinase 95240.m00211.AA p70 158-374 41 9.6e-90 304.45 In-house 71-299 (299) Show / Hide 
Range on Protein: 158-374
Range on HMM: 71-299/299
Sequence Identity: 41% (95 aa)

QIEQILTEKNVLLKSTFPFLVSAHFTFQNEDKIFMVIDYVPGGELFSRLKEEQKFSENRARLYAAEIALGLGHLHSLGFVYRDLKPENILVDENGHLKIT
..|. . | |.|     ||..  |. || . | . . .| .|||||  |...  . |. |. |..|| . |.|||..| .||||||||.. .. ||.. |
RLERTFAERNILEEVKHPFICDLHYAFQTNGKLYLILEYLHGGELFMHLERHGIWMEDTACFYLSEIICALEHLHQHGIIYRDLKPENCMLNQQGHVVLT

DFGLAKGKMGTNTT----------TSTFCGTPEYIAPEILQQFPYTKAVDWWSFGILLFEMLTGLPPFYDENMTKMYRSIINDP--ISYPPYLSPNACSL
|||| | ..   .           | |||||.|| |||||    . .|||||| |.|.. |||| |||  ||  |   .|.     .. ||||.. .  |
DFGLCKESIHDGAVDEEDPENVNATHTFCGTIEYMAPEILMRCGHNHAVDWWSLGCLMYDMLTGGPPFTGENRKKTIDKILKGKQGLKLPPYLTHEMRDL

LSKLLERDPNLRLGGGDRDFEEIKEHPFF
. ||| |.| .|.|.|  | ..|.|||||
IKKLLKRHPTQRWGAGPEDAADIQEHPFF
Kinase 95240.m00211.AA TyrKc 117-374 21 5.6e-16 35.61 SMART 1-280 (280) Show / Hide 
Range on Protein: 117-374
Range on HMM: 1-280/280
Sequence Identity: 21% (63 aa)

FQILSVLGRGTYGKVQLVKYKKTGQIFAMKSMSKRLLEEFDQIEQILTEKNVLLKS--TFPFLVSAH-FTFQNE------DKIFMVIDYVPGGELFSRLK
 . . .||.| .|.| . ..|   .  | |.. .        .| .. | ... |     | .|  .    | .      . ...|  |.|.| | ..|.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

EEQK-FSENRARLYAAEIALGLGHLHSLGFVYRDLKPENILVDENGHLKITDFGLAKGKMGT-------NTTTSTF--CGTP----EYIAPEILQQFPYT
. .. ..      ..  || |  .||| ... |||   |.||.||.. ||.||||..             . ...   .|         ||| ..   .|
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

KAVDWWSFGILLFEMLT-GLPPFYD-----ENMTKMYRSIINDPISYPPYL---------SPNACSLLSKLLERDPNLRLGGGDRDFEEIKEHPFF
 . | ||||....|..| | .| ..      . . ... . .     .|           ..   .. ..  ..||. |       |.||  | .|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRP-----TFSEI--HECF
Kinase 95240.m00211.AA Pkinase_Tyr 187-327 27 5.6e-16 54.75 Pfam 77-228 (270) Show / Hide 
Range on Protein: 187-327
Range on HMM: 77-228/270
Sequence Identity: 27% (44 aa)

EDK--IFMVIDYVPGGELFSRLKE----EQKFSENRARLYAAEIALGLGHLHSLGFVYRDLKPENILVDENGHLKITDFGLAKGKMGTNTT-TSTF----
..   |..|  |.|.| | . |..    .|...  .   ....|| |. .|.| ... |||   |.||.||.. ||.|||||.  . . .  ...     
GEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKL

----CGTPEYIAPEILQQFPYTKAVDWWSFGILLFEMLT-GLPP-FYDENMTKMYRSI
    .      ||| ..   .| . | ||||.|..|..| |  | ...   . .|. |
PIKWM------APECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI
Kinase 95240.m00211.AA p70 117-151 47 1.3e-10 34.81 In-house 1-38 (299) Show / Hide 
Range on Protein: 117-151
Range on HMM: 1-38/299
Sequence Identity: 47% (18 aa)

FQILSVLGRGTYGKVQLVKYKK---TGQIFAMKSMSKR
|. | |||.| |||| .|.  .   ||.|.||| . |.
FELLKVLGKGGYGKVFQVRKVTGEDTGKIYAMKVLRKA
Kinase 95240.m00211.AA S_TK_X 375-438 27 4.3e-10 40.79 SMART 1-79 (79) Show / Hide 
Range on Protein: 375-438
Range on HMM: 1-79/79
Sequence Identity: 27% (22 aa)

ASLDWDDVIA--RKTTPEWIPPLT----SVSDVSHFDQQFTTESIAASIETGPSLSNETQKV----------FVGFTCVD
...|||.. .  ....| ..|...    |  |.| ||. || |..     . | |||  .            | ||| | 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 95240.m00211.AA Pkinase_C 394-440 31 8.6e-08 30.73 Pfam 1-46 (46) Show / Hide 
Range on Protein: 394-440
Range on HMM: 1-46/46
Sequence Identity: 31% (15 aa)

PLTSVSDVSHFDQQFTTESIAASIETGPSLSNETQKVFVGFTCVDES
 ..|  |.|.|| .|| |.   .  ... .|.. |  |.||| | ..
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFTYVNPD
Kinase 95240.m00211.AA Pkinase_Tyr 117-131 33 0.969059 3.13 Pfam 1-15 (270) Show / Hide 
Range on Protein: 117-131
Range on HMM: 1-15/270
Sequence Identity: 33% (5 aa)

FQILSVLGRGTYGKV
 ... .||.| .|.|
ITFGKKLGEGAFGEV