Gene 92605.m00032 (T.vaginalis)

92605.m00032

Species: T.vaginalis
Alias: TvagK0737, 92605.m00032
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: MST

Sequence

Name Sequence Type Origin Length Description Download
92605.m00032.AA Protein None 340 None Fasta, JSON
92605.m00032.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of 92605.m00032.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 92605.m00032.AA STE 33-289 27 3.9e-92 312.41 In-house 1-359 (359) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-359/359
Sequence Identity: 27% (102 aa)

FQIIREIGRGGFGAVYEMLHTQ---------------SGYRLAGKVVNEESMSS---------------SAKQSLLKEIDLLKKIN--SPYTVQYFGNII
...|..||.|.|| ||  ..                 .| . | |..| |. ..               . .|..||||...|| |  .|. |.|.|  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

FN-------KQQMILMEYCDRGSFRDMIDYRNLCLT-------------EKQAAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGIRLTDFGISR
 .        .  | |||.| ||..|.|. .  |.              |.| |......| |.| .. .|.. |||||.|||||     . |.|||.. 
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCG

DFSG----------------GTLNTMSSIGTPYWMAPEVINS------QPYSYPADIWSIGATTIELVEGAPPYCELEPTKAMMNIAAH-----------
 ..                 .  .. . .||| |||||||.       ..|.. .||||.| | ||...| ||.... |..||..|.             
QLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLC

----GFPGFRA-----------------PRAVTKEFKDFIAHTMSKDPKNRCTIPQLLK--HPWI
    . | .                   |. ...||||||..   |||..| |  ||||  ||.|
IVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 92605.m00032.AA STE20 33-289 34 7.5e-89 301.48 In-house 1-288 (288) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-288/288
Sequence Identity: 34% (101 aa)

FQIIREIGRGGFGAVYEMLHTQSGYR----LAGKVVNEESMSS--SAKQSLLKEIDLLKKINSPYTVQYFGNIIFNKQQ----MILMEYCDRGSFRDMID
......||.|..|.||   |...|       | |..| |. .     .....|||. .|. ..|. |.|.|  . ..       |.||||. || .|...
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQDEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIMK

---YRNL-----CLTEKQAAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGIRLTDFGISRDFSGG---TLN-T-MSSIGTPYWMAPEVINS---
    ..       ..|.| | . ..|| |   || .... ||||||.|||| .|| . |.||| . ...     | . .  . .|||||||||||.    
HCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLH-SNHIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCMEG

--QPYSYPADIWSIGATTIELVEGAPPYCELEPTKAMMNIA--AHGFPGFRA--PRAVTKEFKDFIAHTMSKDPKNRCTIPQLLKHPWI
  ..| | .|||| | |.||..|| |||... |..||. |.    ..| ..   |.  ..||.||...   |||..| |  ||||||.|
PDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 92605.m00032.AA S_TKc 33-289 28 4.6e-79 269.88 SMART 1-231 (231) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-231/231
Sequence Identity: 28% (77 aa)

FQIIREIGRGGFGAVYEMLHTQSGYRLAGKVVNEESMSSSAKQSLLKEIDLLKKINSPYTVQYFGNIIFNKQQMILMEYCDR--GSFRDMIDYRNL----
..|.|.||.|.|| ||   |. .| . | |...         .....||..||| . |. |.... .   .   . |||||   |. .|.|. |.     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

-CLTEKQAAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGIRLTDFGISRDFSGGTLNTMSSIGTPYWMAPEVINSQPYSY-PADIWSIGATTIE
  ..| .|. ... .....  .| . ...|||.| .|||| .   | ..|||..| .       .. .|||..|||||.   .|.. ..|.||.| . .|
FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LVEGAPPYCELEPTKAMMNIAAHGFPGFRAPRAVTKEFKDFIAHTMSKDPKNRCTIPQLLK-------HPWI
.. | ||..     ..|...              ..|.|||| . . |||..| |. ..|.       |||.
MLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 92605.m00032.AA MST 33-289 40 1.5e-77 246.02 In-house 1-254 (254) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-254/254
Sequence Identity: 40% (105 aa)

FQIIREIGRGGFGAVYEMLHTQSGYRLAGKVVNEESMSSSAK-QSLLKEIDLLKKINSPYTVQYFGNII--FNKQQMILMEYCDRGSFRDMIDYRNLCLT
| |.  .|.| .| ||  .| |.|  .| |.|. ..       |...|||  ..  .|.| |.|.|. .   |..  | ||||. ||  |..  ..  |.
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKMVPVNE-----DLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLN

EKQAAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGIRLTDFGISRDFSGGTLNTMSSIGTPYWMAPEVINSQPYSYPADIWSIGATTIELVEGA
| | | . .|.| |   ||  .|. ||||||.||||  .|   | ||| |   .  .    . ||||||||||||. . | . ||||| | | ||. || 
EQQIACILYDTLQGLQYLHDNKKI-HRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTVIGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEGM

PPYCELEPTKAMMNIAAHGFPGFRAPRAVTKEFKDFIAHTMSKDPKNRCTIPQLLKHPWI
||| .. |. ||  |     |.|. |     || ||...   |.|  | |  |||.|| |
PPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 92605.m00032.AA PAKL 33-289 39 4.3e-77 262.44 In-house 1-256 (256) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-256/256
Sequence Identity: 39% (103 aa)

FQIIREIGRGGFGAVYEMLHTQSGYRLAGKVVNEESMSSS-AKQSLLKEIDLLKKINSPYTVQYFGNIIFN-KQQMILMEYCDRGSFRDMIDYRNLCLTE
| .    | |..|.||  .|  ..  || ||    ..  |   ... |||..||| ..|. | ||| |     .  |||.||  ||..||.      |.|
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVI---EIKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNE

KQAAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGIRLTDFGISRDFSGGTLN--TMSSIGTPYWMAPEVINSQPYSYPADIWSIGATTIELVEG
|| ..... .| |   || |  . |||||||||||  |. . . |||.|     ...     . ||||||||||.|| |.| . .|||| | | ||. .|
KQISVILQQTLKGLHYLHSK-NIIHRDIKAANILLNEDCQVKIADFGVSQQLQ-DEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADG

APPYCELEPTKAMMNIAAHGFPGFRAPRAVTKEFKDFIAHTMSKDPKNRCTIPQLLKHPWI
 ||  .. |..||. |     | |  |.   ..| ||.|    |||  |    .|| || |
FPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase 92605.m00032.AA YSK 33-289 36 4.5e-69 207.0 In-house 1-257 (257) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-257/257
Sequence Identity: 36% (96 aa)

FQIIREIGRGGFGAVYEMLHTQSGYRLAGKVVNEESMSSSAKQSLLKEIDLLKKINSPYTVQYFGNIIFNKQQMILMEYCDRGSFRDMIDYRN---LCLT
| .   |||| || ||     . .   | |... |. .      . .||  |    |||  .|.|         | ||||  || .| .  .      . 
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEIED-IQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLM--KPKYVGQFD

EKQAAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGIRLTDFGISRDFS--GGTLNTMSSIGTPYWMAPEVINS--QPYSYPADIWSIGATTIEL
||. ||... .| |   || . ...||||||||.||  .| . | |||..         .||.  .|||||||||||      | . |||||.| |..|.
EKYIAIILREILKGLDYLH-SERKIHRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTF--VGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEM

VEGAPPYCELEPTKAMMNIAAHGFPGFRAPRAVTKEFKDFIAHTMSKDPKNRCTIPQLLKHPWI
  | ||||...| ..| .|     |     |  .| ||.|..    |||..| .  .||||  |
AKGEPPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase 92605.m00032.AA Pkinase 33-289 28 4.3e-66 230.67 Pfam 1-293 (293) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-293/293
Sequence Identity: 28% (85 aa)

FQIIREIGRGGFGAVYEMLHTQSGYRLAGKVVNEESMSSSAKQSLLK--EIDLLKKINSPYTVQYFGNIIFNKQQMILMEYCDRG----SFRDMID-YRN
..|.| ||.|.|| ||.  |  .| . | |... .. .|. .|....  || ..|..|.|. |....    ..   . ||||. |    .  |.|   |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

LCL--TEKQAAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGI----RLTDFGISRDF-SGGTLNTMSSIGTPYWMAPEVIN-SQPYSYPADIWS
 |.  .|...  ... .|.|.  .|  ....|||.| .|||. ..| |    ...|||... |       ...  |||..||||||. .|.|....|.||
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

IGATTIELVEGAPPYCEL----EPTKAMMNIAAHGFPGFRAPRAVT---------------------KEFKDFIAHTMSKDPKNRCTIPQLLKHPWI
.| . .|.. | ||...     .    |  |.  . | .. ..  .                     .|.||||     |||| |.|..|.|.|||.
CGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 92605.m00032.AA SLK 33-289 36 1.2e-64 216.93 In-house 1-259 (259) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-259/259
Sequence Identity: 36% (96 aa)

FQIIREIGRGGFGAVYEMLHTQSGYRLAGKVVNEESMSSSAKQSLLKEIDLLKKINSPYTVQYFGNIIFNKQQMILMEYCDRGSFRDMIDYRNLCLTEKQ
..|| |.| | || ||   | . .   | |..  |  .    .  . |||.| ... |. |. ..   .... ....|.|| |    ..   .  |||.|
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMI--EIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQ

AAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGIRLTDFGISRDFSGGTLNTMSSIGTPYWMAPEVI-----NSQPYSYPADIWSIGATTIELVE
 ..| | .. ..  || . ||.|||.|| |||.  ||..|| |||.|           . |||||||||||.       ||| | |||||.| | ||. .
IQYVCKHMCEALNWLHSN-KVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQ

GAPPYCELEPTKAMMNIAAHGFPGFRAPRAVTKEFKDFIAHTMSKDPKNRCTIPQLLKHPWI
. ||. |..| . .. |.    |    |   .||||||. ... |||.|| |  ||..|.|.
MEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase 92605.m00032.AA PAKA 33-289 33 3.6e-60 206.22 In-house 1-260 (260) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-260/260
Sequence Identity: 33% (88 aa)

FQIIREIGRGGFGAVYEMLHTQSGYR--LAGKVVNEESMSSSAKQ-SLLKEIDLLKKINSPYTVQYFGNIIFNKQQMILMEYCDRGSFRDMIDYRN---L
.. . .|| |. |.||.   .. . .   | |. |   |.   |   .. || ..|. . .  |.|    ... .  . ||| . |.  | |.  .   .
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMN---MKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQC

C-LTEKQAAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGIRLTDFGISRDFSGGTLNTMSSIGTPYWMAPEVINSQPYSYPADIWSIGATTIEL
  ..|.|.| |.. .|.|.  .| || . |||||  |||| .|| . .||||     .   .   .  |||||||||||. . |..  ||||.|  .||.
NYMDEGQIAYVCRECLQGLEFIHSKH-RIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEM

VEGAPPYCELEPTKAMMNIAAHGFPGFRAPRAVTKEFKDFIAHTMSKDPKNRCTIPQLLKHPWI
.|| ||| .  | .||  ||. | | .. |  ...||.|| .    .|...| .  .||.|| .
IEGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 92605.m00032.AA CAMK 38-289 18 1.1e-59 190.63 In-house 1-425 (425) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-425/425
Sequence Identity: 18% (78 aa)

EIGRGGFGAVYEMLHTQSG------------YRLAGKVVNEESMS--------------------------SSAKQSLLKEIDLLKK-------INSPYT
..|||.|| |..  |....             . | |... . ..                           . ......||...||       .. |  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQYFG-----------NIIF---------NKQQMILM---EYCDRG----SFRDMIDYRNLC--------------LTEKQAAIVIKDVLSGILILHTKH
.. .            |. .         .|.  . |   |||. |       |.|  .  .              .||..|. ... ..|..  .| ..
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

KVLHRDIKAANILLMSDG----------------G-IRLTDFGISRDFSGGTLNTMS-----------------------SIGTPYWMA-PEVINS----
 . |||.|  |||| ...                . | ..||| .. | .|  |.|                        . |||. || |||.|.    
-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

----------QPYSYPADIWSIGATTIELVEGAPPYC---------------ELEPTKAMMNIAAHGFPGFR--------------------APRAVTKE
          ..|....|.||.|  .  .. | ||.                ... .. .   .   || .                      .  |..|
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQE

FKDFIAHTMSKDPKNRCTIPQLLKHPWI
 ||.| . . .||..| || | |.|||.
CKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 92605.m00032.AA STE11 39-289 32 2e-59 203.72 In-house 7-303 (303) Show / Hide 
Range on Protein: 39-289
Range on HMM: 7-303/303
Sequence Identity: 32% (98 aa)

IGRGGFGAVYEMLHTQSGYRLAGKVVNEESMSS------SAKQS------LLKEIDLLKKINSPYTVQYFGNII---FNKQQMILMEYCDRGSFRDMID-
||.| || ||  . .  | ..| | . .. ...         ||      . .|| |.|..| .  |.|.|  .    |.   | ||||  || ..|.. 
IGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSLSSMLRH

-YRNLCLTEKQAAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGG-IRLTDFGISRDFSGGTLNTMS----------SIGTPY--------WMAPE
 .  . ..|.   . .|..|.|.  || .|.. |||||.|||||.|||. ..|.|||... ... ...| .            ||||        |||||
KWGPMKFDEMVIRKYTKQILEGLQYLH-SHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLAWICTCTHNMNMTQNHCKSMTGTPYNSMMGTPMWMAPE

VINSQP---YSYPADIWSIGATTIELVEGAPPYCELE--PTKAMMNIAAHGFPGFRAPRAVT------KEFKDFIAHTMSKDPKNRCTIPQLLKHPWI
||. ..   |. .|||||.|.| || . | ||. ...  .  ||. |...  |    |  ..       | .||. |.  .||| | |  |||.||.|
VIKQEGRDGYGRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIPEHMSPISWISEECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase 92605.m00032.AA KHS 33-289 35 2.9e-57 191.13 In-house 1-258 (258) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-258/258
Sequence Identity: 35% (93 aa)

FQIIREIGRGGFGAVYEMLHTQSGYRLAGKVVNEESMSSSAKQSLLKEIDLLKKINSPYTVQYFGNIIFNKQQMILMEYCDRGSFRDMIDYRNLCLTEKQ
....  .| | .| ||   ..||.   | ||.  |   .   ... .|| ..|.   |  | |||  . ...  | ||||  ||  |.       |.| |
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIKME--PGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTG-PLSELQ

AAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGIRLTDFGISRDFSGGTLNTMSSIGTPYWMAPEVINSQP---YSYPADIWSIGATTIELVEGA
 | | ...| |.  ||.. | .||||| ||||| ..| ..| |||.| . .       | |||||||||||   .    |    |||..| | ||| |  
IAYVCRETLQGLHYLHSMGK-MHRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQ

PPYCELEPTKAMMNIAAHGF--PGFRAPRAVTKEFKDFIAHTMSKDPKNRCTIPQLLKHPWI
||  .| | .|.. ..  .|  |  .  .  .. | .|.  .. |.|| | |  .||.||..
PPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase 92605.m00032.AA Pkinase_Tyr 33-241 23 2.5e-18 62.67 Pfam 1-225 (270) Show / Hide 
Range on Protein: 33-241
Range on HMM: 1-225/270
Sequence Identity: 23% (54 aa)

FQIIREIGRGGFGAVYEMLHT----QSGYRLAGKVVNEESMSSS-AKQSLLKEIDLLKKI-NSPYTVQYFGNII-FNKQ--QMILMEYCDRGSFRDMIDY
 ......|.| || ||.   .    . ..  | |...| .|..   ......|. ..|.. . |  |.. | ..   ..   .| |||.  |. .|    
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

R---NLCLTEKQAAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGIRLTDFGISRDF-SGGTL-NTMSSIGTPY-WMAPEVINSQPYSYPADIWS
.   .  || |.      .. .|   |. |.   |||. | |.|. ... .. .||| .||  . ..   . ..   |  |||||.||   ..   |.||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN-CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

IGATTIELVE-GAPP-YCELEPTKAM
 | .  |..  |. | | .. ..  .
FGVLMWEIFTYGEQPTYPGMSNEEVY
Kinase 92605.m00032.AA TyrKc 33-289 21 8.5e-16 32.69 SMART 1-280 (280) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-280/280
Sequence Identity: 21% (62 aa)

FQIIREIGRGGFGAVYEMLHTQSGYRLAGKVVNEESMSSSAKQSLLKEIDLLKKI--NSPYTVQYFGNIIFN-------KQQMILMEYCDRGSFRDMI-D
 . ....|.| || ||.   .   .  | |...|..     .. ...|. ...|.  . |  |. .| ..         .. ||.|||.. |. .| . .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

YRNLCLTEKQAAIVIKDVLSGILILHTKHKVLHRDIKAANILLMSDGGIRLTDFGISRDFSGG-------TLNTMSS-IGTP-----YWMAPEVINSQPY
.|.  |. |.      .. .|   || | .. |||. | |.|. ... .. .||| |||   .          ....  |.       |||||.||   .
HRPK-LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

SYPADIWSIGATTIELVE-GAPPYCE-----LEPTKAMMNIAAHGFPGFRAPRA------VTKEFKDFIAHTMSKDPKNRCTIPQLLKHPWI
.   |.|| | .  |.   |..|| .     .... .. .. . . .   .          ..|  . .      ||..|.|  ..  |  .
TTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF