Gene 81864.m00296 (T.vaginalis)

81864.m00296

Species: T.vaginalis
Alias: 81864.m00296, TvagK0579
External Links:
Annotation:

Classification

Group: CMGC
Family: CDK
Subfamily: CDK7

Sequence

Name Sequence Type Origin Length Description Download
81864.m00296.AA Protein None 300 None Fasta, JSON
81864.m00296.kin_dom Protein Kinase Domain None 282 None Fasta, JSON

Protein domain

Protein domains of 81864.m00296.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81864.m00296.AA CMGC 9-290 20 7.3e-89 292.06 In-house 1-513 (513) Show / Hide 
Range on Protein: 9-290
Range on HMM: 1-513/513
Sequence Identity: 20% (106 aa)

FNRKKKLGRGGFGIVYIAED--------------TVTKETLALKKIMVRSPKDGIEY----------HAIQEIRQLNELQ-----------------HPN
.   ||.|.| .|.|| . |              . |.|  |.|||. .  ..  .            |. ||. | .|.                 |.|
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

IVKFNGVFTHK-----------------FTLYLSTEYLPYELIHLFNKYPD-------HKLPINI------------VKCVM------KGVLQALS--YM
|||   .|.||                   ||| .||... | ..  ....       ..|.               .|. |      . .|..|   |.
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HNSK--IMHRDIKPDNVLFDKNGVP--------------------KLIDFGLSCDFPSDFGP---------------------MICQATTLNYRAPELLF
|  .  |.|||.|| |.|...|.                      |..||||.. . .  ..                     .  .  |. |||||.|.
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

SQ---------NNYGSEIDMWSTGAMFAELLLG--------KPIFD-----------APNDIHLLSQIAKTLGTI------------------EWSGCEK
.          ..|...||||| | .|||...|        ||.|              ..|. | .| |.|||.                  || .. |
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

IRAYMK---------------------------FSAPEGFSISTFDDKFKE-----------------------FGN----------DALSLLKSLLVLD
   | |                           |  . . ... .  ....                       | |          .|. ||| .|..|
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKF-NHQFKRKCCDPQAIDLLKKMLQYD

PSKRITADEALKHPFL
|.|||||..||.||..
PDKRITAEQALQHPYF
Kinase 81864.m00296.AA CDK7 9-290 36 3.4e-83 221.31 In-house 1-288 (288) Show / Hide 
Range on Protein: 9-290
Range on HMM: 1-288/288
Sequence Identity: 36% (106 aa)

FNRKKKLGRGGFGIVYIAEDTVTKETLALKKIM----VRSPKDGIEYHAIQEIRQLNELQHPNIVKFNGVFTHKFTLYLSTEYLPYELIHLFNKYPDHKL
..  |..| | |. || | |..| .  | |||         ||||.  || ||  | |.||.|..    .| ||  ..|  ....  | .      | ..
YEKIKHIGEGQFATVYKACDHQTGQIVAIKKIKKLGHRSEAKDGINRTAIREIKILQEMQHDNVIGLIDIFMHKSNIQLVFDFMDWDLEVVIK---DKSI

---PINIVKCVMKGVLQALSYMHNSKIMHRDIKPDNVLFDKNGVPKLIDFGLSCDFPSDFGPMICQATTLNYRAPELLFSQNNYGSEIDMWSTGAMFAEL
   | .| |  |. .|| | |.|   | |||.|| | |...||. |. ||||   ..|       |. |  ||||||||    ||. .|||| |  ||||
ILTPAHI-KAYMMMTLQGLEYCHRNWILHRDLKPNNLLMNENGQLKIADFGLARFYGSPNRIYTHQVVTRWYRAPELLFGARHYGTGVDMWSVGCIFAEL

LLGKPIFDAPNDIHLLSQIAKTLGT---IEWSGCEKIRAYMKFSAPEGFSISTFDDKFKEFGNDALSLLKSLLVLDPSKRITADEALKHPFL
.|  |..   .||  |. | .||||    || .  ..  |.||    |.|   ... |   ..|.| |.. .. ..|.||.|. ..||.|. 
MLRVPYLPGDSDIDQLTRIFQTLGTPTEEEWPNMCCMMDYIKFKDFPGYSRTPLRHIFTAASDDLLDLMCGMWTMNPCKRWTCTQCLKMPYF
Kinase 81864.m00296.AA S_TKc 9-290 26 1.1e-80 275.25 SMART 1-231 (231) Show / Hide 
Range on Protein: 9-290
Range on HMM: 1-231/231
Sequence Identity: 26% (80 aa)

FNRKKKLGRGGFGIVYIAEDTVTKETLALKKIMVRSPKDGIEYHAIQEIRQLNELQHPNIVKFNGVFTHKFTLYLSTEYLPY---ELIHLFNKYPDHK--
.   .|.|.|.|| || . .. |..  |.|.|           |...||. | . .||||||. .|| .   ||. .||..    .| ..  |.. |.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LPINIVKCVMKGVLQALSYMHNSKIMHRDIKPDNVLFDKNGVPKLIDFGLSCDFPSDFGPMICQATTLNYRAPELLFSQNNYGS-EIDMWSTGAMFAE
  .|   ....|. ...|| |.|. .|.|||.||.|.|.|.  . |..||||.. .         .  |..|.|||.|     ||  ..|.|| | ...|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGCILYE

LLLGKPIFDAPNDIHLLSQIAKTLGTIEWSGCEKIRAYMKFSAPEGFSISTFDDKFKEFGNDALSLLKSLLVLDPSKRITADEALK-------HPFL
.| |.| |.   ..... .. .                                       .|..... .|. ||.||.|| |||.       ||..
MLCGYPPFP---QMQMMFKKIG-------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81864.m00296.AA CDK 9-290 32 2.9e-79 253.23 In-house 1-284 (284) Show / Hide 
Range on Protein: 9-290
Range on HMM: 1-284/284
Sequence Identity: 32% (105 aa)

FNRKKKLGRGGFGIVYIAEDTVTK-----ETLALKKIMVRS-----PKDGIEYHAIQEIRQLNELQHPNIVKFNGVFTHK-----------FTLYLSTEY
. . .|.|.| .|.|| | |. |.     .  |||||.. .      |.|.   || ||  | || ||||||   |...|            .||.  ||
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL-HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFEY

LPYELIHLFNKYPDHKLPINIVKCVMKGVLQALSYMHNSKIMHRDIKPDNVLFDKNGV-----PKLIDFGLSCDFPS----DFGPM--IC-QATTLNYRA
... | ..             .|| |.  |..|.|.|  .|||||.|| | | ..||.      |. ||||.. | .    . .|.     .  || |||
MDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMS-EPNRTYTHEVVTLWYRA

PELLFSQNNYG--SEIDMWSTGAMFAELLL---GKPIFDAPNDIHLLSQIAKTLGTI---EWSGCEKIRAYMKFSAPEGFSISTFDDKFKEFGNDALSLL
||||. . .|.   .||||| |  |||...   .||.|   ..|. |  | ...||     | |..|   |                           ||
PELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICGTPTEDNWPGVTKLPDY--------------------------DLL

KSLLVLDPSKRITADEALKHPFL
 ..|..||.|||.|..||.||..
NKMLCYDPKKRISAEQALQHPYF
Kinase 81864.m00296.AA CDC2 9-290 34 1.3e-76 234.88 In-house 1-301 (301) Show / Hide 
Range on Protein: 9-290
Range on HMM: 1-301/301
Sequence Identity: 34% (105 aa)

FNRKKKLGRGGFGIVYIAEDTVTKETLALKKIMVRSPKDG--IEYHAIQEIRQLNELQ-HPNIVKFNGVFTHKFTLYLSTEYLPYELIHLFN-KYP-DHK
. . .|.| | .|.|| ..|. |..  ||||| . .  .|  .   || ||  | ||. ||||||   |.     ||. .||| . |  .   . | . .
YQKIEKIGEGTYGVVYKCKDMQTNQIVALKKIRLEQEDEGDGVPSTAIREISCLKELKDHPNIVKLHDVIHQ-NKLYMVFEYLDMDLKKYMDMSIPKNKH

LPINIVKCVMKGVLQALSYMHNSKIMHRDIKPDNVLFDKNGVPKLIDFGLSCDFPSDFGPMI--CQATTLNYRAPELLFSQNNYGSEIDMWSTGAMFAEL
.| ..||  |.  ||.... |  .|||||.||.| | ||.|. |. ||||. .|.    .        || |||||.|. .  |  ..|||| |  |||.
MPPQLVKSYMYQILQGVHFCHQRRIMHRDLKPQNILIDKKGNIKIADFGLARAFGIPIRTYTTEHEVVTLWYRAPEILLGCKRYSTPVDMWSIGCIFAEM

---LLGKPIFDAPNDIHLLSQIAKTLGT---IEWSGCEKIRAY-MKFSAPEGFSISTFDDK------FKEFGNDALSLLKSLLVLDPSKRITADEALKHP
      ||.| .   |  | .| ..|||    .| |...   | ..|   .   .|.   .      . .  .....||...|..||.|||.|.|||.||
FMDVTKKPLFHGDSEIDQLFKIFRILGTPNEQTWPGVTQLPDYKNTFPRWKPQDLSKICPNNQKKKNQSCLDPEGIDLLMQMLQYDPQKRISAKEALQHP

FL
..
YF
Kinase 81864.m00296.AA Pkinase 9-290 27 1.9e-73 255.14 Pfam 1-293 (293) Show / Hide 
Range on Protein: 9-290
Range on HMM: 1-293/293
Sequence Identity: 27% (83 aa)

FNRKKKLGRGGFGIVYIAEDTVTKETLALKKIMVRSPKDGIEYHAIQ--EIRQLNELQHPNIVKFNGVFTHKFTLYLSTEYLPYELIHLFNKY------P
. ...|.|.|.|| ||.. .  | .. |.|.| .|. |.. .....   ||. ...|.|||||.. ..|. |  .|. .||..  |  ..  .       
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLY-VMDLFDYISTWR

DHKL--PINIVKCVMKGVLQALSYMHNSKIMHRDIKPDNVLFDKNGVP----KLIDFGLSCDF-PSDFGPMICQATTLNYRAPELLFSQNNYGSEIDMWS
. ..  . . .|..|. .|..| |.|. .|.|||.||.|.|.|.||..    |..||||.. |     . |   . |..|.|||.. ... ||...||||
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWS

TGAMFAELLLGKPIFDAP------NDIHLLSQIAKTLGTIEWSGCEKIRAYMKFSAPEGFSISTFDDKFKEFGNDALSLLKSLLVLDPSKRITADEALKH
 | ...|.|.|.|.|.        ...... .| ..    .|.    |. .. |.  .      .  . ..   ......|..| .||.||.||...|.|
CGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--F-HWTF-HNWSEECKDFIKWCLCKDPKKRPTAEQILQH

PFL
|..
PWF
Kinase 81864.m00296.AA CDK5 9-290 31 2.6e-58 182.61 In-house 1-287 (287) Show / Hide 
Range on Protein: 9-290
Range on HMM: 1-287/287
Sequence Identity: 31% (91 aa)

FNRKKKLGRGGFGIVYIAEDTVTKETLALKKIMVRSPKDGIEYHAIQEIRQLNELQHPNIVKFNGVFTHKFTLYLSTEYLPYELIHLFNKYPDHKLPINI
...  |.| | .|.|| | .  |.|  |||..   |   |.   || ||  | ||.|.|||    |      | |  |..   |   ...  . ..  .|
YEKMEKIGEGTYGTVYKARNKETHEIVALKRVRLDSEDEGVPSTAIREICLLKELKHKNIVRLHDVIHSEKKLTLVFEFCDQDLKKYMDSCNG-EMDMHI

VKCVMKGVLQALSYMHNSKIMHRDIKPDNVLFDKNGVPKLIDFGLSCDFPSDFGPMICQATTLNYRAPELLFSQNNYGSEIDMWSTGAMFAELL-LGKPI
.|  |   |. |.. |. ...||| || | |  |||  || ||||   |            || ||.|  |.    |   ||||| |  |||.   |.| 
IKSFMYQLLKGLAFCHEHHVLHRDLKPQNLLINKNGELKLADFGLARAFGIPVRCYSHEVVTLWYRPPDVLMGSKHYSTSIDMWSCGCIFAEMANAGRPL

FDAPNDIHLLSQIAKTLGT---IEWSGCEKIRAYM-KFSAPEGFSIST-FDDKFKEFGNDALSLLKSLLVLDPSKRITADEALKHPFL
|   ..   | .| | .||    .| .  |   |  .  . . .   . .    ..     . ||. .|...| .||.|..||.||. 
FPGNDVEDQLKRIFKIMGTPCEDKWPSITKLPDYKPNHQQYPMYPAHQSWQQIVPKLDEKGMDLLQKMLQCNPNQRISAKAALHHPYF
Kinase 81864.m00296.AA Ciliate-E2 9-290 22 3.8e-57 194.72 In-house 1-365 (365) Show / Hide 
Range on Protein: 9-290
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

FNRKKKLGRGGFGIVYIAEDTVT--------------------KETLALKKIMVRSPK----DGIEYHAIQEIR----------QLNELQHPNIVKFNGV
..  ||.|.|.||.|| ...  .                    | .  .. . . ...       | | ..||.           | .|.||||.|.  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FT--HKFTLYLSTEYLPY-ELIH-------LFNKYPD--HKLPINIVKCVMKGVLQ---------------ALSYMHNSK-IMHRDIKPDNVLFDKNGVP
|    . ..|| .||. . .| .        .|. ..  ... .. .| .|| .||               || |.|. . |.||||||.|.||     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLIDFGLSC----------------DFPSDFGPMICQAT----------------TLNYRAPELLFSQNN--------YGSEIDMWSTGAMFAELLLGKP
|.||||||                  ..  .. .  . .                |..| ||| | ....        |. ..|.|| | .. |.| |||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

IFDAPNDIHLLSQIAKTLGTIEWSGCEKIRAYMKFSAPEGFSISTFDDK-FKEFGNDALSLLKS----LLVLDPSKRIT-ADEALKHPFL
 |          |. .  . |. .  |..    .    . ...     | .|.  ...  |.|     .|. ||.|||| ....|.||..
PF----------QQQIKQCKIDFPCPEWQKD-TQ-CI-Q-CKW-----KSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 81864.m00296.AA CAMK 14-290 18 2.7e-55 176.26 In-house 1-425 (425) Show / Hide 
Range on Protein: 14-290
Range on HMM: 1-425/425
Sequence Identity: 18% (82 aa)

KLGRGGFGIVYIAEDTVTK------------ETLALKKIMVR-SPK-------------------------DGIEYHAIQEIRQLNELQ-------HPNI
.||||.||.|. .... |.            .  | | |  .  ..                         .  .    .||. .. ||       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VKFNGVFTHKFT-------------------LYLST---EYLPY-EL----IHLFNKYPD-------------HKLPINIVKCVMKGVLQALSYMHNSKI
.|.  |.  ..                    .|. .   || .  ||         . ..             ....   .. ... ...|. |.|. .|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

MHRDIKPDNVLFDKN-----------------GVPKLIDFGLSCDFPSDFG-----------------------PMICQATTLNYRA-PELLFS------
.|||.||.|.|.|.|                 .  |.||||... |... .                       .|  .  |. | | ||.| .      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

-------QNNYGSEIDMWSTGAMFAELLLGKPIFDAPNDIHLLSQIAKTLGTIEW------SGCEKIRAYMKFSAPEGFSISTFDDKFKEFGN-------
       .  || ..|||| | .   .| |.| |....|   .. . .      |        .|||..      |. ||... . . .|. .       
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICE-D-E------WIGMNDYELFEKIMKGKYDFPPPYFSPISCN-YGPEWWDDISDEFH

-----DALSLLKSLLVLDPSKRITADEALKHPFL
     .. .|....|. ||.||.|....|.||..
HFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 81864.m00296.AA CDK10 9-290 32 1.1e-53 184.68 In-house 1-285 (285) Show / Hide 
Range on Protein: 9-290
Range on HMM: 1-285/285
Sequence Identity: 32% (93 aa)

FNRKKKLGRGGFGIVYIAEDTVTKETLALKKIMVRSPKDGIEYHAIQEIRQLNELQHPNIVKFNGVF--THKFTLYLSTEYLPYELIHLFNKYPDHKLPI
| .  ..| | .|||| | |. ..|  ||||. .   |||.   .. ||  | ...|.|||.   |    |   ..|  .|   .|  | .  | .    
FEKLNRVGEGTYGIVYRARDMRSDEIVALKKVRMDKEKDGLPISGLREIMLLIQCRHENIVELHEVVVGQHLDSIFLVMQYCEQDLASLLDNMP-QPFTE

NIVKCVMKGVLQALSYMHNSKIMHRDIKPDNVLFDKNGVPKLIDFGLSCDFPSDFGPMICQATTLNYRAPELLFSQNNYGSEIDMWSTGAMFAELLLGKP
  |||.|  .|..| |.|.  ..|||.|  |.|.  .|  |. ||||   .     ||  .  || |||||||.   .    ||||  | . .|||..||
TQVKCIMLQMLRGLKYLHDNFMIHRDLKVSNLLMTDKGCIKVADFGLARMYGVPVKPMTPKMVTLWYRAPELLLGCRTQTTAIDMWAVGCILGELLVHKP

IFDAPNDIHLLSQIAKTLGTIE---WSGCEKIRAYMKFSAPEGFSISTFDDKFKEFGNDALSLLKSLLVLDPSKRITADEALKHPFL
..    .|| .  | . ||| .   | |  .. .  .|.  .         ||.  ..  . ||. |.. .| || ||.|.|.  . 
LMPGNSEIHQIDMIIDLLGTPSENIWPGFSDLPMVQNFTL-KKQPYNNLKHKFHWLSQSGRRLLNFLFMYNPKKRATAEECLESSYF
Kinase 81864.m00296.AA Ciliate-E2-Unclassified 9-290 22 5.8e-52 178.53 In-house 1-352 (352) Show / Hide 
Range on Protein: 9-290
Range on HMM: 1-352/352
Sequence Identity: 22% (84 aa)

FNRKKKLGRGGFGIVYIAEDTVTKETLALKKIMVRSPKD-----GIEYHAIQEIRQLNELQ-------------------HPNIVKFNGVFTHKFTLYLS
..  |..|.||||.|| ...  .|.  |.| ...   ..       .   ..|. ..|...                   ||.|||.  .|. |...|. 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

TEYLPY-ELIHLFNKYPD---------------HKLPINIVK-----CVMKGVLQALSYMHNSK-IMHRDIKPDNVLFDKNG---VPKLIDFGLSC---D
.||... .|.   .|..                .... . .|       .. .||.|.|.| .. | ||||||.|.|||.||    .|.||||.|    .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

FPSDF----------GPMICQAT--TLNYR----APELLFSQNNYGS---EIDMWSTGAMFAELLLGKPIFDAPNDIH----------------LLSQI-
.. .            ..... .  |.||     |||.| .||...|   ..|.|| |  . |.| |.. |...|..                 |...| 
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

AK-TLGTIEWSGCEKIRAYMKFSAPEGFSISTFDDKFKEFGNDALS-LLKSLLVLDPSKRITADEALKHPFL
.| .    .. .                    ....  . . | .. ||...|. .|.||||....|.||..
QKNIQFPKFPWQQ-------------------IPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 81864.m00296.AA MAPK 9-226 26 2.8e-35 119.34 In-house 1-253 (328) Show / Hide 
Range on Protein: 9-226
Range on HMM: 1-253/328
Sequence Identity: 26% (69 aa)

FNRKKKLGRGGFGIVYIAEDTV------TKETLALKKIM--VRSPKDGIEYHAIQEIRQLNEL-QHPNIVKFNGVFTHK-----------FTLYLSTEYL
..  |..| | .|.|  | |.       .... |.|||.   ..| .    ... ||. |... .|.||.| . .|| .            ..|. .|. 
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCK--RTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELM

PYELIHLFNKYPDHKLPINIVKCVMKGVLQA--LSYMHNSKIMHRDIKPDNVLFDKNGVPKLIDFGLSCDFPSD-------FGPMICQA---------TT
   | .. .  .  .|    ..  |  .| .  | |.|   . |||.|| |.| ..|.  |. ||||.. . ..       . | .| .         .|
ETDLHQIIKSQQ--PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDP-HC-FQKMHMTEYVAT

LNYRAPELLFS--QNNYGSEIDMWSTGAMFAELLL-GKPIFDAPNDIHLLSQIAKTLGT
  |||||....   ..|   .|||| |  |||.|  .||.|   . |. . .| ..|||
RWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGT
Kinase 81864.m00296.AA MAPK 262-290 55 3.1e-15 48.93 In-house 300-328 (328) Show / Hide 
Range on Protein: 262-290
Range on HMM: 300-328/328
Sequence Identity: 55% (16 aa)

DALSLLKSLLVLDPSKRITADEALKHPFL
.|. ||. .||.||.||||..||| ||..
QAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase 81864.m00296.AA TyrKc 9-290 18 6e-12 -29.5 SMART 1-280 (280) Show / Hide 
Range on Protein: 9-290
Range on HMM: 1-280/280
Sequence Identity: 18% (60 aa)

FNRKKKLGRGGFGIVYIAEDTVTKETLALKKIMVRSPKDGIEYHAIQEIRQLNEL--QHPNIVKFNGVFTHK-------FTLYLSTEYLPYELIHLFNKY
   .||||.| ||.|| .. .   .. | |..   .     .   ..|.| . .|  .|||||.. || |..         |.. .|| |.   . . ..
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

PDHKLPINIVKCVMKGVLQALSYMHNSKIMHRDIKPDNVLFDKNGVPKLIDFGLSCDFPSD-----FGPMICQ----ATT--LNYR--APELLFSQNNYG
. .||.       .  . .  .| |  .. |||.   |.| ..|.. |  ||||| |  .|      . .. .     .   | .|  ||| .   . . 
HRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYGKFT

SEID----------MWSTGAMFAEL-----LLGKPIFDAPNDIHLLSQIAK----TLGTIEWSGCEKIRAYMKFSAPEGFSISTFDDKFKEFGNDALSLL
.. |          . . |..  .      .  . ..    . . . | .                                      | .   .  .. 
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------------FVCCPDEMYQIM

KSLLVLDPSKRITADEALKHPFL
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KQCWHEDPEDRPTFSEI--HECF
Kinase 81864.m00296.AA APH 128-155 31 0.000713 14.09 Pfam 172-203 (248) Show / Hide 
Range on Protein: 128-155
Range on HMM: 172-203/248
Sequence Identity: 31% (10 aa)

IMHRDIKPDNVLFD--KNGVPK--LIDFGLSC
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WCHGDFHPGNVMWDPRPDGGRVTGVIDWDDAC