Gene 88808.m00139 (T.vaginalis)

88808.m00139

Species: T.vaginalis
Alias: 88808.m00139, TvagK0398
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
88808.m00139.AA Protein None 469 None Fasta, JSON
88808.m00139.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of 88808.m00139.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 88808.m00139.AA PH 12-107 23 7.2e-13 49.99 SMART 1-82 (82) Show / Hide 
Range on Protein: 12-107
Range on HMM: 1-82/82
Sequence Identity: 23% (23 aa)

LSYAGWLKKKSRLHGFWHQRFVSLEGDQLTIYKDDTRQVVEERLKLYPDTKAEITQTKKFSIFNIGETKANMLFLADSIEDATRWVTAIHAVSLPS
. . |||.|||     |..|.. | .|.|..|||.      ... |    . .      | |.. ..    ..| ..| |....|..||.... ..
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P--CFEIHH-DR---TYYFQCESEEEMQEWMQAIQKAIHNN
PH 88808.m00139.AA PH 12-105 24 1.9e-08 33.15 Pfam 1-92 (92) Show / Hide 
Range on Protein: 12-105
Range on HMM: 1-92/92
Sequence Identity: 24% (24 aa)

LSYAGWLKKKSRLHGFWHQRFVSLEGDQLTIYKDDTRQVVEERLKLYPDTKAEITQTKK------FSIFNIGETKANMLFLADSIEDATRWVTAIHAVSL
. . |||.||.   . |..|.. | ...| .||||.    ..  . .|  ....| ...      | | . ..     .| |.| |....|..||.... 
VIKEGWLHKKG-KRKSWKKRWFVLFNNCLYYYKDDK----YRPKGSIPLSDCQVTKVPDNKRPHCFQIRT-DR--RTYYFQAESEEEMNDWMQAIQSACR
Kinase 88808.m00139.AA AGC 115-366 29 6.6e-144 374.77 In-house 1-395 (395) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-395/395
Sequence Identity: 29% (117 aa)

FNIISLIGKGFYGKVRLCQKK------DTGDLYAIKSVHKSI-LIKTG--RTCAVIAE------------RNLMMKAK----------FPFLVS-LHFTF
|... .|||| .|||.|..||      |||..||.| . |.   ...       ...|            || ..|..           ||.|. ||..|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTRSK--FYFGLEYVP---------GG-DLKFHKS---QVGKIPIFDAKLYAAQ-------IGLAITYLHG-IGIVYRD-LKPENVLLDGQGYIKLVDFG
|. ..   || .||.|         || .| .|.    . |. .   |. |||.       | ||. |||   ||..|| |||||.||| .|.|||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKDIN---------------------------------------------------QVKTTRTFCG--TPEYISPELILKKNYGYAVDEWA--LGVLMY
|.| ..                                                   . ..| ||||  ||||..|| .    ||.|.| |.  ||.|||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EIIFGDPPFVDEN----------ENKLYDKIV------LEEPKYP----------ADADPNLVDIIKKLLVKDPAKRPK----------FIDLKSHPFF
| ..| ||| ..|          ......||        ...|.|             .|...|.|||||.|||.||.           . ..|.||.|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 88808.m00139.AA Akt 115-366 40 6.5e-109 349.31 In-house 1-264 (264) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-264/264
Sequence Identity: 40% (107 aa)

FNIISLIGKGFYGKVRLCQKKDTGDLY-AIKSVHKSILIKTGRTCAVIAERNLMMKAKFPFLVSLHFTFQTRSKFYFGLEYVPGGDLKFHKSQVGKIPIF
|... ..||| .||| |..||||...| |.|.  |. .|. .    ...|||.  . ..||.|.||. |||  | || ..|..||.| .| .. ....  
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

DAKLYAAQIGLAITYLHGIGIVYRD-LKPENVLLDGQGYIKLVDFGLSK-D-INQVKTTRTFCGTPEYISPELILKKNYGYAVDEWA-LGVLMYEIIFGD
 |. |.|.| ||| .||  .|.||| |||||.|.| .|.|.| ||||.| . | .  .| ||||||||..|| .... .. ||| |. ||..||| ..| 
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGR

PPFVDENENKLYDKIVLEEPKYP--ADADPNLVDIIKKLLVKDPAKRP-KFID----LKSHPFF
||| ...  ....||  .. |.|     .|.  |.|..|| ||| ||.  ...    .|.||.|
PPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 88808.m00139.AA SGK 115-366 39 3.9e-105 325.67 In-house 1-283 (283) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-283/283
Sequence Identity: 39% (112 aa)

FNIISLIGKGFYGKVRLCQKKDT------------------GDLYAIKSVHKSILI-------KTGRTCAVIAER-NLMMKAKFPFLVSLHFTFQTRSKF
| ....|||| .||| . ..||.                  ...||.|   |   |       |      . ||| ... . | ||.|.||. |||  | 
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YFGLEYVPGGDLKFHKSQVGKIPIFDAKLYAAQIGLAITYLHGIGIVYRDLKPENVLLDGQGYIKLVDFGLSK-DINQVKTTRTFCGTPEYISPELILKK
|| ..|| ||.. .|    .. |   |. |||.| .|. ||| . |.||||||||.||| ||...| ||||.| .| . .|| ||||||||  || ..|.
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

NYGYAVDEWALGVLMYEIIFGDPPFVDENENKLYDKIVLEEPKYPADADPNLVDIIKKLLVKDPAKR--PK--FIDLKSHPFF
 .. .|| | || ..|| ..| ||| . | . .||.|  .. . |    .   |.|. || ||| ||   |  |.. |.||||
PHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPPQMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 88808.m00139.AA AktR 115-366 42 1.3e-102 347.15 In-house 1-268 (268) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-268/268
Sequence Identity: 42% (113 aa)

FNIISLIGKGFYGKVRLCQKK-DTGDLYAIKSVHKSILIKTGRTCAVIAERNLMM-KAKFPFLVSLHFTFQTRSKFYFGLEYVPGGDLKFHKSQVGKIPI
| .. ..||| .||| |.||| |....||.|...|. .|.  .  ..| ||| |  ....||.| ||..|||..| .| .||.|||.| .| .. .|.  
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

FDAKLYAAQIGLAITYLHGI-GIVYRDLKPENVLLDGQGYIKLVDFGLSK---DINQVKTTRTFCGTPEYISPELILK-KNYGYAVDEWALGVLMYEIIF
 .|. |.||| ||. |||    |.|||||||| |||  |..|..||||||   ..    ....|||||||..|| |.| | ....|| ||.|.. ||...
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GDPPFVDENENKLYDKIVLEE---PKYPADADPNLVDIIK-KLLVKDPAKRPK-----FIDLKSHPFF
| ||| ..| | ...||  ..   ..||..  ... |.|. ||| |.| ||..     . ..||||.|
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 88808.m00139.AA PKC 115-366 42 3.6e-94 305.65 In-house 1-262 (262) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-262/262
Sequence Identity: 42% (112 aa)

FNIISLIGKGFYGKVRLCQKKDTGDLYAIKSVHKSILIKTGRTCAVIAERN-LMMKAKFPFLVSLHFTFQTRSKFYFGLEYVPGGDLKFHKSQVGKIPIF
|| .  .||| .||| |  .|.|  .|||| . | . |..     . .|.  |   .| |||..|| .||| .. .| .||| |||| ||  |... .  
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

DAKLYAAQIGLAITYLHGIGIVYRDLKPENVLLDGQGYIKLVDFGLSKD-INQVKTTRTFCGTPEYISPELILKKNYGYAVDEWALGVLMYEIIFGDPPF
 |. ||| | .|  .||  ||.||||| .|||||  | ||..|||..|. ... .||.||||||.||.|| .  . || .|| ||.||||||   | .||
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQEYGKSVDWWAFGVLMYEMMAGQSPF

VDENENKLYDKIVLEEPKYPADADPNLVDIIKKLLVKDPAKR------PK--FIDLKSHPFF
  |.|  | . |  ..| || .     |.|.|... |.|.||      ..  . | ..||||
HGEDEDELFQSIMHDNPHYPRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 88808.m00139.AA S_TKc 115-366 34 1.4e-91 311.49 SMART 1-231 (231) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-231/231
Sequence Identity: 34% (92 aa)

FNIISLIGKGFYGKVRLCQKKDTGDLYAIKSVHKSILIKTGRTCAVIAERNLMMKAKFPFLVSLHFTFQTRSKFYFGLEYVPG--GDLKFHKSQVGK---
. |. .|||| .|||..|..|.|| ..||| ..          . .. |.....| . |..| |. .||. ...|. .||..|  |||. .  . |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---IPIFDAKLYAAQIGLAITYLHGIGIVYRDLKPENVLLDGQGYIKLVDFGLSKDINQVKTTRTFCGTPEYISPELILKKNYGY-AVDEWALGVLMYEI
   .|  .|. |..|| .|. |.|  ||..|||||||.|||    ||. ||||.. .      .||||||.|..||..    ||. ..| |..|...|| 
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

IFGDPPFVDENENKLYDKIVLEEPKYPADADPNLVDIIKKLLVKDPAKRPKFIDLKS-------HPFF
. | |||   .......||.          .| . |.|.|.|.|||.|||   ..         ||.|
LCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 88808.m00139.AA PKA 115-366 41 1.8e-87 296.92 In-house 1-263 (263) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-263/263
Sequence Identity: 41% (110 aa)

FNIISLIGKGFYGKVRLCQKKDTGDLYAIKSVHKSILIKTGRTCAVIAERNLMMKAKFPFLV-SLHFTFQTRSKFYFGLEYVPGGDLKFHKSQVGKIPIF
|.|| ..|.| .|.|.||..|..|. ||.|   |.  ...  .  |. |.| ..  |.||.| .. .|||.... |. .||||||..  .   .|. .  
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

DAKLYAA-QIGLAITYLHGIGIVYRDLKPENVLLDGQGYIKLVDFGLSKDINQVKTTRTFCGTPEYISPELILKK-NYGYAVDEWALGVLMYEIIFGDPP
.||.||| || ||. |||   |.|||||||| |.| .|.||. ||| .| .     | | ||||||. || |. |  .| .|| ||||.| ||  .| ||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPP

FVDE--NENKLYDKIVLEEPKYPADADPNL---VDIIKKLLVKDPAKRP---KF--IDLKSHPFF
| |.  . ...|.||.  . |.|   |...    | |||||..|. ||    |.   | | |..|
FYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 88808.m00139.AA MAST 115-366 31 4.3e-84 270.95 In-house 1-334 (334) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-334/334
Sequence Identity: 31% (105 aa)

FNIISLIGKGFYGKVRLCQKKDTGDLYAIKSVHKSILIKTGRTCAVIAERNLMMKAKFPFLVSLHFTFQTRSKFYFGLEYVPGGDLKFHKSQVGKIPIFD
|..| .|.|| |||| |  .|.|.|..|.| . || .|.   .  |..|||    .. || |..  .|||... .. .||. |||.... . .|  .   
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

AKLYAAQIGLAITYLHGIGIVYRDLKPENVLLDGQGYIKLVDFGLSKD---------------------------INQVKTTRTF---------------
||.| |.. |.. |||  ||| |||||.|.|.|  | |||.||||||                             || .....                
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

------------------------CGTPEYISPELILKKN-YGYAVDEWALGVLMYEIIFGDPPFVDENENKLYDKIVLEE---PKYPAD--------AD
                        ||||.||.||.||..  .| .|| |..|. |||.. | |||.|.. ......|. ..    ..| .          
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

PNLVDIIKKLLVKDPAKRPKFI----DLKSHPFF
|   |.|.|||  || ||. .     . |.||||
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase 88808.m00139.AA RSK 118-366 36 5.5e-80 272.05 In-house 1-278 (278) Show / Hide 
Range on Protein: 118-366
Range on HMM: 1-278/278
Sequence Identity: 36% (101 aa)

ISLIGKGFYGKVRLCQKK---DTGDLYAIKSVHKSILIKTGR-TCAVIAERNLMMKAK-FPFLVSLHFTFQTRSKFYFGLEYVPGGDLKFHKSQVGK---
... |.| |||| ||.|.   ||| .|| | ..|. .... . |  . .||| ..  .  ||.|.|| .||| .|.|  .||..||.|  | .. .    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

IPIFDAKLYAAQIGLAITYLHGIGIVYRDLKPENVLLDG---QGYIKLVDFGLSKD-INQ-VKTTRTFCGTPEYISPELIL---KKN-YGYAVDEWALGV
.   .|. |.|.| ||. .||  ||..|||||||.|.|    .| |||.|||..|   ..  . | |||.| ||. ||..    ... .. |.| | |||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LMYEIIFGDPPFVD---ENENKLYDKIVLEE--PKYP--ADADPNLVDIIKKLLVKDPAKRPK-----FIDLKSHPFF
||||  .| |||     .| ... ..|   .  .. |  .   ..  |.|.|.| .||.||..       ..|.||.|
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 88808.m00139.AA Alpha 115-366 45 5.6e-80 272.02 In-house 1-259 (259) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-259/259
Sequence Identity: 45% (118 aa)

FNIISLIGKGFYGKVRLCQKKDTGDLYAIKSVHKSILIKTGRT-CAVIAERNLMMKAKFPFLVSLHFTFQTRSKFYFGLEYVPGGDLKFHKSQVGKIPIF
|| .. .||| .||| |  .| |  |||||   | . | .    |  .  | | .  | ||||..| .|||    || .||| |||| .|  ||||    
FNFLMVLGKGSFGKVMLAERKGTDELYAIKILKKDVIIQDDDVECTMVEKRVLALPGKPPFLVQMHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGKFKEP

DAKLYAAQIGLAITYLHGIGIVYRDLKPENVLLDGQGYIKLVDFGLSK-DINQVKTTRTFCGTPEYISPELILKKNYGYAVDEWALGVLMYEIIFGDPPF
 |  ||| |  .  .||  ||.|||||  ||.||. | ||..|||..| .... .|||||||||.|| || |.   || .|| || |||.||.. | |||
HAVFYAAEIAIGLFFLHEKGIIYRDLKLDNVMLDAEGHIKIADFGMCKENMWEDQTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMMAGQPPF

VDENENKLYDKIVLEEPKYPADADPNLVDIIKKLLVKDPAKR-----PKFIDLKSHPFF
  | |. |.  |   .. ||       |||.| .|.| |.||         | . ||||
DGEDEDELFQAIMEHNVSYPKSMSKEAVDICKGFLTKHPNKRLGCGPDGEQDIREHPFF
Kinase 88808.m00139.AA Eta 115-366 42 2.1e-79 270.1 In-house 1-261 (261) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-261/261
Sequence Identity: 42% (110 aa)

FNIISLIGKGFYGKVRLCQKKDTGDLYAIKSVHKSILIKTGR-TCAVIAERNLMMKAKFPFLVSLHFTFQTRSKFYFGLEYVPGGDLKFHKSQVGKIPIF
|| |  .||| .||| | ..|.|...|||| . | ..|.     | .   | | . .| ||| .|| .|||. . .| .||| |||| |.  .  |    
FNFIKVLGKGSFGKVMLAERKGTDEVYAIKVLKKDVIIQDDDVECTMTEKRILSLARKHPFLTQLHCCFQTKDRLFFVMEYVNGGDLMFQIQRARKFDEP

DAKLYAAQIGLAITYLHGIGIVYRDLKPENVLLDGQGYIKLVDFGLSKD-INQVKTTRTFCGTPEYISPELILKKNYGYAVDEWALGVLMYEIIFGDPPF
 |. ||| . .|. .||  |..||||| .|.||| .|  || |||. |. |.. .|| ||||||.|| ||..   .|| .|| ||.||||||.. | |||
RARFYAAEVTCALMFLHQHGVIYRDLKLDNILLDHEGHCKLADFGMCKEGIMNGMTTTTFCGTPDYIAPEILQEMEYGPSVDWWAMGVLMYEMMCGQPPF

VDENENKLYDKIVLEEPKYPADADPNLVDIIKKLLVKDPAKRPKFI-------DLKSHPFF
  .||  |.. |. ..  ||     . | |.|  . | | ||   .       ....||||
EADNEDDLFESILHDDVLYPVWLHKEAVSILKAFMTKNPHKRLGCMTAQGGEHAIRQHPFF
Kinase 88808.m00139.AA Pkinase 115-366 30 6e-72 250.13 Pfam 1-293 (293) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

FNIISLIGKGFYGKVRLCQKKDTGDLYAIKSVHKSILIKTGRTCAVIA--ERNLMMKAKFPFLVSLHFTFQTRSKFYFGLEYVPGG----DLKFHKS--Q
. |.. ||.| .|.|..|..|.||...|.| . |.  .| .   . .   |  .| . . |. | |. .|..... |. .||..||    ||. . |  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

VGKI--PIFDAKLYAAQIGLAITYLHGIGIVYRDLKPENVLLDGQGYI----KLVDFGLSK---DINQVKTTRTFCGTPEYISPELIL-KKNYGYAVDEW
 |..  .  ..| |. ||  .. |.|  ||..|||||||.|.| .|.|    |. ||||.|     |..  . ||||||.|..||.|.  . ||..|| |
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

ALGVLMYEIIFGDPPFVDE------NENKLYDKIVLEEPKYPADAD---------------------PNLVDIIKKLLVKDPAKRPKFIDLKSHPFF
..|...|| ..| ||| ..      ........|   ..... . .                     ... |.||..| |||.||| . ... ||.|
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 88808.m00139.AA TyrKc 115-366 22 1.5e-15 28.71 SMART 1-280 (280) Show / Hide 
Range on Protein: 115-366
Range on HMM: 1-280/280
Sequence Identity: 22% (65 aa)

FNIISLIGKGFYGKVRLCQKKDTGDLYAIKSVHKSILIKTGRTCAVIAERNLMMKA--KFPFLVSLHFTFQTR-------SKFYFGLEYVPGGDLK----
   .  .| |..|.|.... |      |.|.....         . . | ..|.|   . | .| |.    .           .  .||.|.||||    
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

FHKSQVGKIPIFDAKLYAAQIGLAITYLHGIGIVYRDLKPENVLLDGQGYIKLVDFGLSKDINQV-------KTTRTFC--GTPE-----YISPELILKK
 |. .   ..  |   .. ||     |||  ... |||   |.|.. .. .|  |||||.||          .. |.    |.         .|| | ..
KHRPK---LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

NYGYAVDEWALGVLMYEII-FGDPPFVD------ENENKLYDKIVLEEPKYPAD--------ADPNLVDIIKKLLVKDPAKRPKFIDLKSHPFF
 .  . | |. ||.|.||  .|..|  .      .|.  . .    . .. |..        . . . .|.|.    ||..|| | ..  | .|
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 88808.m00139.AA S_TK_X 367-427 26 2.2e-11 45.08 SMART 1-79 (79) Show / Hide 
Range on Protein: 367-427
Range on HMM: 1-79/79
Sequence Identity: 26% (21 aa)

ADIDFKKVYN--KEYKPSYVPKLT----TRLSLENFDPYITNENPNDSYVSPAIGEIGN------------ISGFNFVD
..||..|.||  ||..| ..||..        ..||||  |.| | .. ..|.. .. .              ||..| 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 88808.m00139.AA Pkinase_Tyr 115-306 23 2.4e-05 18.73 Pfam 1-208 (270) Show / Hide 
Range on Protein: 115-306
Range on HMM: 1-208/270
Sequence Identity: 23% (50 aa)

FNIISLIGKGFYGKVRLCQKK----DTGDLYAIKSVHKSILIKTGR---TCAVIAERNLMMKA-KFPFLVSLHFTFQ-TRSK--FYFGLEYVPGGDLK-F
  ..  .|.| .|.|...  |    .|.   |.|.. |     . .     . ..| ..|..  . | .|.|.      .     |  .||.|.|||. .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KE--GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDY

HKSQ---VGKIPIFDAKLYAAQIGLAITYLHGIGIVYRDLKPENVLLDGQGYIKLVDFGLSKDI----NQ-VKTTRTFCGTPEYISPELILKKNYGYAVD
 ...    ..... |   ...||  .  ||. .... |||   |.|.. .. .|  ||||..||    .  .|.. .        .|| |  . .  . |
LRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGK-LPIKWMAPECINYGKFTTKSD

EWALGVLMYEII
 |. ||||.||.
VWSFGVLMWEIF