92921.m00274

Species: T.vaginalis
Alias: TvagK0420, 92921.m00274
External Links:
Annotation:

Classification

Group: AGC
Family: PDK1

Sequence

Name Sequence Type Origin Length Description Download
92921.m00274.AA Protein None 428 None Fasta, JSON
92921.m00274.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of 92921.m00274.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 92921.m00274.AA AGC 35-297 28 6.8e-135 350.93 In-house 1-395 (395) Show / Hide
Range on Protein: 35-297
Range on HMM: 1-395/395
Sequence Identity: 28% (114 aa)

FNIGKVIGRGAFGEVLKVQDI------ETGKYYAMKVLSKSR-ISREK--KINYVILE------------RDAMNALN----------HPNIIR-LYLTF
|.. ||||.|.||.|  |..        ||||||||||.|.. | . |  .. ... |            |. .  .|          ||.|.. |. .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDNSN--LYYVVELAD---------NG-DLQHVLN---QYVSLDIPIAKQILGQ-------ILLALAHMHQ-RRIIHRD-IKPENILLDHNNSVKITDFG
||...  || | |..           | .| . |    .. ..| . |. .. .       |.||| ..|. . ||||| .||||||||..  .|.||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

TAKM--------------------------------------YKRDEPFY----------SQHGSLVG--SPDYVSPETLNETPISAATDLWS--FGCLV
 .|.                                       .|.  ..           .  ...|  .|.|..|| |     . | | ||  .||| 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNN-MSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLM

YQFFTGYAPFHTSS----------NYETFQKIE------SGKYTIP----------DFVPADAKDLITKLLKLNPEERIGYNDFD---KGYETIKSHPFF
|.. ||| ||.  .           .|.||||.      . | ..|          ...  .|||||.|||. .||.|.|... |   ||.| ||.||.|
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF





Kinase 92921.m00274.AA PDK1 35-297 38 8.99999999999e-119 365.61 In-house 1-307 (307) Show / Hide
Range on Protein: 35-297
Range on HMM: 1-307/307
Sequence Identity: 38% (118 aa)

FNIGKVIGRGAFGEVLKVQDIET----GKYYAMKVLSKSRISREKKINYVILERDAMNALN-----HPNIIRLYLTFQDNSNLYYVVELADNGDLQHVLN
| .||.||.|....| .. ..||    .| || |...|. | ||||. ||. |...|. ||     ||.|..|| ||||...||.| |.. |||| | ..
FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKICEKRYIIREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQDEQCLYFVLEYCPNGDLLHYMK

Q--YVSLDIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDHNNSVKITDFGTA---KMYKR-----------------------DEPFYSQHGSLV
   . |.|.  ..    .|..|| |.| . |||||.|||||||| .. ..|||||||   |                           .|. ..  .| |
KQPFGSFDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQQHNKGMDKPEEDKQTRCKSFV

GSPDYVSPETLNETPISAATDLWSFGCLVYQFFTGYAPFHTS-----SNYETFQKIESGKYTIPDF--VPADAKDLITKLLKLNPEERIGYNDFDKGYET
|   ||||| |.. ... ..|.|..||..||...|  ||  .     . | |||||    |..||   .| .||||. |||...| .|..  |   ||..
GTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIMKCQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTSCDECGGYQQ

IKSHPFF
|| ||||
IKAHPFF

Kinase 92921.m00274.AA S_TKc 35-297 32 7.3e-100 338.98 SMART 1-231 (231) Show / Hide
Range on Protein: 35-297
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

FNIGKVIGRGAFGEVLKVQDIETGKYYAMKVLSKSRISREKKINYVILERDAMNALNHPNIIRLYLTFQDNSNLYYVVELADN--GDLQHVLNQYVS---
. |...||.||||.| |.....||...|.|...          . .. |.. .   .||||..|| .||| ..|| | |..|.  ||| ... .. .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LDIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDHNNSVKITDFGTAKMYKRDEPFYSQHGSLVGSPDYVSPETLNETPISA-ATDLWSFGCL
   ..   |. .. ||..||...|...|||||.||||||||.   .||.||| |. .           ...|.|.|..|| |   . .  . | ||.||.
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

VYQFFTGYAPFHTSSNYETFQKIESGKYTIPDFVPADAKDLITKLLKLNPEERIGYNDFDKGYETIKSHPFF
.| ...|| ||.    ...|.||           . .|||.| |.|. .||.|..  .  .. . ||.||.|
LYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 92921.m00274.AA Pkinase 35-297 28 4e-89 307.2 Pfam 1-293 (293) Show / Hide
Range on Protein: 35-297
Range on HMM: 1-293/293
Sequence Identity: 28% (88 aa)

FNIGKVIGRGAFGEVLKVQDIETGKYYAMKVLSKSRISREKKINYVI-LERDAMNALNHPNIIRLYLTFQDNSNLYYVVELADNG----DLQHVLN--QY
. ||..||.|.||.| | ... ||| .|.|...|.... .|... .   |   |. ||||||.||| .|.|....| | |....|    || ...   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

VSL--DIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDHNNSV----KITDFGTAKMYKRDEPFYSQHGSLVGSPDYVSPETLN-ETPISAATDLW
 ..  .   .| .. ||| .|...|...|||||.||||||.|.|. .    ||.||| || ..  .  .|   ...|.|.|..|| ..  .... . | |
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SFGCLVYQFFTGYAPFHTS------SNYETFQKIESGKYTIPDFVP---------------------ADAKDLITKLLKLNPEERIGYNDFDKGYETIKS
|.||..|....|. ||  .      . .. ...| ....  . . .                      ..||.|...|...|..|..        | |. 
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-------AEQILQ

HPFF
||.|
HPWF

Kinase 92921.m00274.AA CAMK 40-297 21 1.6e-83 268.86 In-house 1-425 (425) Show / Hide
Range on Protein: 40-297
Range on HMM: 1-425/425
Sequence Identity: 21% (92 aa)

VIGRGAFGEVLKVQDIETG------------KYYAMKVLSKSRIS-------------------------REKKINYVILERDAMNA-------LNHPNI
..|||.||.| ......|.            . .|.|...|....                         |.|.   |  | . |.        |.||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRLYLTFQD-------------------NSNLYYVV---ELADNG----DLQHVLNQY---------------VSLDIPIAKQILGQILLALAHMHQRRI
|.|| ...|                   ....| |    |....|    ||   . .                  ..   |...  ||. |....|.. |
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENILLDHN-----------------NSVKITDFGTAKMYKRD------------EPFYSQ----------HGSLVGSPDYVS-PETLN-----
.|||.||||||||.|                 | .||.||| |......            | . ..              .|.| |.. || ||     
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

---------ETPISAATDLWSFGCLVYQFFTGYAPFHTS-------------SNYETFQKIESGKYT-IPDFVPA-----------------------DA
         ..... ..| || |.. |   .|| ||  .             . ||.|.|| .|||. .|....                        ..
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

KDLITKLLKLNPEERIGYNDFDKGYETIKSHPFF
|||| |.|. .||.|.   .       ...||..
KDLIRKMLQVDPEKRMTIEQ-------CLNHPWM

Kinase 92921.m00274.AA Ciliate-E2 35-297 26 4e-83 282.45 In-house 1-365 (365) Show / Hide
Range on Protein: 35-297
Range on HMM: 1-365/365
Sequence Identity: 26% (101 aa)

FNIGKVIGRGAFG-----EVLKVQDIE------------------TGKYYAMKVLSKSRISREKKINYVI----------LERDAMNALNHPNIIRLYLT
... |.||.|.||     .| |||  .                  ..|.||||...|. |   |......           |.  .  |||||||..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DNSNLYYVVELADNGDLQHVLN------------QYVSLDIPIAKQILGQILL---------------ALAHMHQRR-IIHRDIKPENILLDHNNS
||  |..|.|.| |... |||.. ..            .  ....  .|.|  |||                || ..|..  ||||||||||||.     
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

VKITDFGTAKMYKRDEP---------FYSQHGS--------------------LVGSPDYVSPETLNETP---------ISAATDLWSFGCLVYQFFTGY
.||.|||..| |. |.           | . ..                    ..|.| |..|| ||  .          . . |.||.|.. |.. .|.
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

APFHTSSNYETFQKIESGKYTIPDF------------------VPADAKDLITK----LLKLNPEERIGYNDFDKGYETIKSHPFF
 ||        .|.|. .|. .| .                  .. ..|||| |    .|. .||.||.      |.| |. ||.|
PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT------GWEQILNHPWF

Kinase 92921.m00274.AA RSK 38-297 33 2e-78 266.84 In-house 1-278 (278) Show / Hide
Range on Protein: 38-297
Range on HMM: 1-278/278
Sequence Identity: 33% (94 aa)

GKVIGRGAFGEVLKVQDI---ETGKYYAMKVLSKSRISREKK-INYVILERDAMNALN-HPNIIRLYLTFQDNSNLYYVVELADNGDLQHVLNQYVS---
 || |.|..|.|  .. .    ||..||||||.|. | . .| . ..  ||. . . . ||.|..|. .||... || . |.   |.|   | . ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LDIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDH---NNSVKITDFGTAKMYKRD--EPFYSQHGSLVGSPDYVSPETLN----ETPISAATDLW
..   |.... .| ||. |.||. |||||.||||||.|.   . ..|.|||| .|  . |  .. ..     ... .|. || |.    .   ..| |.|
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT----FCYTIEYMAPEMLKRANQQGGHDKACDWW

SFGCLVYQFFTGYAPFHT---SSNYETFQKIESGK--YTIP--DFVPADAKDLITKLLKLNPEERIGYNDFDKGYETIKSHPFF
|.|.| |  .||. ||.    ..  |....|..||   |.|  ... ..|||||.|.|. .|. |.|..   .. | ||.||.|
SLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCG--PQDAEEIKQHPWF

Kinase 92921.m00274.AA Ciliate-E2-Unclassified 35-297 27 7.4e-75 255.01 In-house 1-352 (352) Show / Hide
Range on Protein: 35-297
Range on HMM: 1-352/352
Sequence Identity: 27% (98 aa)

FNIGKVIGRGAFGEVLKVQDIETGKYYAMKVLSKSRISREKKINYV---ILERDAMNALN-------------------HPNIIRLYLTFQDNSNLYYVV
..|.|.||.|.||.| |.|......||||| ..|..|   |.|...   ..| ..|| ..                   ||.|.... .|||  |.| | 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

ELADNGDLQHVLNQY-----------------VSLDIPIAK-----QILGQILLALAHMHQR-RIIHRDIKPENILLDHNN---SVKITDFGTAKMYKRD
|....|||.  ....                   ..   ||     ... |||..| ..|.   ||||||||||||.| |.    .||.||| .| |. .
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

EPFYSQHG-------------SLVGSPDYV----SPETLNETPIS----AATDLWSFGCLVYQFFTGYAPF-HTSSNY---------------ETFQKIE
. ..   .             . .|.| |     .|| | .   .     . | ||.|.. |.. .|| ||  ....                . .|.| 
NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

SGKYT--------IPDFVPADAKDLIT----KLLKLNPEERIGYNDFDKGYETIKSHPFF
 ...         ||. ..  |||.|.    |.|| ||..||       ..| |. ||.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI-------TFEQILNHPWF

Kinase 92921.m00274.AA CAMKL 35-297 27 1.5e-73 234.02 In-house 1-297 (297) Show / Hide
Range on Protein: 35-297
Range on HMM: 1-297/297
Sequence Identity: 27% (86 aa)

FNIGKVIGRGAFGEVLKVQD-IETGKYYAMKVLSKSRIS-REKKINY-----------VILERDAMNALN---HPNIIRLYLTFQDNSN------LYYVV
..|||..|.|.||.|   .. . ||. .|.|.. |..|. .... .            .  |   |  ||   |||||.|| .... ..      .| | 
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

ELADNGD--LQHVL--NQYVS--LDIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDHNNS--VKITDFGTAKMYKR-----DEPFYSQHGSLVGS
|....|.  |.. .  . ..   .. . |...  ||. |....|...|.||||||||||||.|..  .||.||| . ||..     .. .  .     ||
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTF----CGS

PDYVSPETLNE--T-PISAATDLWSFGCLVYQFFTGYAPFHTSS---------NYETFQKIESGKYTIPDFVPADAKDLITKLLKLNPEERIGYNDFDKG
| | .|| ..   .  .  ..| || | . |   .|| ||   .         ...  ...  ....|. .|. |..||| |.|. |||.|.        
PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRP-------T

YETIKSHPFF
 . |..||..
IHQIMNHPWM

Kinase 92921.m00274.AA AktR 35-297 38 1e-71 244.58 In-house 1-268 (268) Show / Hide
Range on Protein: 35-297
Range on HMM: 1-268/268
Sequence Identity: 38% (106 aa)

FNIGKVIGRGAFGEVLKVQDI-ETGKYYAMKVLSKSRISREKKINYVILERDAMN-ALNHPNIIRLYLTFQDNSNLYYVVELADNGDLQHVLNQYVSLDI
| . |..|.||||.|  ||.  ...|.||||...|. | ..... ..|.||. |    ||| |..|. .||....|... |   .|.| ..|..   .. 
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

PIAKQILGQILLALAHMHQR-RIIHRDIKPENILLDHNNSVKITDFGTAK---MYKRDEPFYSQHGSLVGSPDYVSPETLNE-TPISAATDLWSFGCLVY
  |. .  |||||| . ||.  || ||.|||||||| .  ||||||| .|   |  .||. |    |..|.| |..||....  .   . |.|.||...|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAY----SFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIY

QFFTGYAPFHTSSNYETFQKIESGK-YTIPDFVPA--DAKDLIT-KLLKLNPEERIGYNDFDKGYETIKSHPFF
   ||. ||  ... . |||| .     .|. ..    .||||. |||. ||..|.||  ...| | |||||.|
EMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGY--YCNGWEEIKSHPWF

Kinase 92921.m00274.AA PKA 35-297 36 1.4e-66 227.46 In-house 1-263 (263) Show / Hide
Range on Protein: 35-297
Range on HMM: 1-263/263
Sequence Identity: 36% (99 aa)

FNIGKVIGRGAFGEVLKVQDIETGKYYAMKVLSKSRISREKKINYVILERDAMNALNHPNIIR-LYLTFQDNSNLYYVVELADNGDLQHVLNQYVSLDIP
|.| ...|.| || |  ... ..|.|||||.|.|..| |.| .  |. |.  .....||.|.. .| ||||...||.| |..  |.... |    ... |
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

IAKQILG-QILLALAHMHQRRIIHRDIKPENILLDHNNSVKITDFGTAKMYKRDEPFYSQHGSLVGSPDYVSPETLNET-PISAATDLWSFGCLVYQFFT
.|| .   || |||  .|.  ||.|| ||||||.| |  .|||||| ||  .  . .     .| | |.|  || .. . .   . | |..|.|.| . .
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTW-----TLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLA

GYAPFHTS--SNYETFQKIESGKYTIPDFVPADA---KDLITKLLKLNPEERIGYNDFDKGYETIKSHPFF
|| ||  .  .  ....|| .||.  | ..  ||   |||| |||  ....|.|  ..  | . || |..|
GYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKN--GVNDIKNHKWF

Kinase 92921.m00274.AA Aur 35-178 39 1e-52 137.12 In-house 1-147 (257) Show / Hide
Range on Protein: 35-178
Range on HMM: 1-147/257
Sequence Identity: 39% (58 aa)

FNIGKVIGRGAFGEVLKVQDIETGKYYAMKVLSKSRISREKKINYVILERDAMNALNHPNIIRLYLTFQDNSNLYYVVELADNGDLQHVLNQY--VSLDI
| |||  |.|.||.|  ... .|.. .|.||..|. |  .. . ..  |   .. ||||||...|  |.|. . | . | | .|.| ..| .    ..| 
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

PIAKQILGQILLALAHMHQRRIIHRDIKPENILLD-HNNSVKITDFG
..|  .  || .|| ..| . |||||||||||||| .|. .|| |||
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFG

Kinase 92921.m00274.AA Aur 201-297 28 2.8e-30 76.66 In-house 166-257 (257) Show / Hide
Range on Protein: 201-297
Range on HMM: 166-257/257
Sequence Identity: 28% (28 aa)

DYVSPETLNETPISAATDLWSFGCLVYQFFTGYAPFHT-SSNYETFQKIE-SGKYTIPDFVPADAKDLITKLLKLNPEERIGYNDFDKGYETIKSHPFF
||..||  .. .     |.|..| | | . .|..||   ..  ||...|   .....|.... .||||| |.|. .|..|.  ..       |..||..
DYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPPFESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQ-------IMNHPWI

Kinase 92921.m00274.AA Pkinase_Tyr 35-251 29 3.7e-19 65.5 Pfam 1-232 (270) Show / Hide
Range on Protein: 35-251
Range on HMM: 1-232/270
Sequence Identity: 29% (72 aa)

FNIGKVIGRGAFGEVLKVQDIETGKYY----------AMKVLSKSRISREKK--INYVILERDAMNAL-NHPNIIRLYLTFQ-DNSN--LYYVVELADNG
  .||..|.|||||| |      |...          | |.| |   . ..   .   . |   |  | .||||.|||     .     .| |.|.. .|
ITFGKKLGEGAFGEVYK------GTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG

DLQHVLNQY----VSLDIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDHNNSVKITDFGTAKMYKRDEPFY-SQHGSLVGSPDYVSPETLNETPI
|| . | .      .|...   |.  ||  .... .....||||.   |.|...|| |||.||| |.    ..  |  ..|.        .|| .|.   
DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKF

SAATDLWSFGCLVYQFFT-GYAP-FHTSSNYETFQKI-ESG
. ..| |||| | .  || |  | .   ||.| ...| |.|
TTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG

Kinase 92921.m00274.AA TyrKc 35-291 24 3.6e-16 38.8 SMART 1-280 (280) Show / Hide
Range on Protein: 35-291
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

FNIGKVIGRGAFGEVLKVQDIETGKYY---AMKVLSKSRISREKKINYVILERDAMNAL--NHPNIIRLYLTFQDN-------SNLYYVVELADNGDLQH
   ||..|.|||||| |      |...   | |.| ..       .   . |   |  |  .||||.|||    .          |. |.|....|||..
ITLGKKLGEGAFGEVYK------GTWKIQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

VLNQYVS-LDIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDHNNSVKITDFGTAKMYKRD------EPFYSQ----HGSLVGSPDYVSPETLNET
 |  .   |  .   ..  ||    .. |....||||.   |.|...|. |||.||| ..  . |      .  |..    .|  .      .||..|. 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

PISAATDLWSFGCLVYQFFT-GYAPFHT-----SSNYETFQKIESGKYTIPDFV---------PADAKDLITKLLKLNPEERIGYNDFDKGYETI
  . ..| |||| . .  || |  |         ||.| ......|..  .            |..  .....  . .||.|   ..    .| .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF

PH 92921.m00274.AA PH 342-428 27 4.1e-05 24.23 SMART 1-82 (82) Show / Hide
Range on Protein: 342-428
Range on HMM: 1-82/82
Sequence Identity: 27% (25 aa)

VIKEGMVVFES---KQRMLVLLEPPKLLICNIDLTQIKKNIPLSNIASVSIQGNELVLVNGLTNAKYEITCDSD-DIQLWLSAIKESISSK
||||| .   |   |.| .|| .   |...  .    |. ||||.. .|.        .   ..  |.. |.|. . | |..||.. |.. 
VIKEGWLYKKSKRWKKRWFVLFN-DCLYYYKDK--KPKGSIPLSDC-TVRE-P--CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN