Gene 92921.m00274 (T.vaginalis)
92921.m00274
Species: T.vaginalis
Alias: TvagK0420, 92921.m00274
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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92921.m00274.AA | Protein | None | 428 | None | Fasta, JSON |
92921.m00274.kin_dom | Protein Kinase Domain | None | 263 | None | Fasta, JSON |
Protein domains of 92921.m00274.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Kinase | 92921.m00274.AA | AGC | 35-297 | 28 | 6.8e-135 | 350.93 | In-house | 1-395 (395) | Show / Hide |
Range on Protein: 35-297 Range on HMM: 1-395/395 Sequence Identity: 28% (114 aa) FNIGKVIGRGAFGEVLKVQDI------ETGKYYAMKVLSKSR-ISREK--KINYVILE------------RDAMNALN----------HPNIIR-LYLTF |.. ||||.|.||.| |.. ||||||||||.|.. | . | .. ... | |. . .| ||.|.. |. .| FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF QDNSN--LYYVVELAD---------NG-DLQHVLN---QYVSLDIPIAKQILGQ-------ILLALAHMHQ-RRIIHRD-IKPENILLDHNNSVKITDFG ||... || | |.. | .| . | .. ..| . |. .. . |.||| ..|. . ||||| .||||||||.. .|.|||| QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG TAKM--------------------------------------YKRDEPFY----------SQHGSLVG--SPDYVSPETLNETPISAATDLWS--FGCLV .|. .|. .. . ...| .|.|..|| | . | | || .||| LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNN-MSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLM YQFFTGYAPFHTSS----------NYETFQKIE------SGKYTIP----------DFVPADAKDLITKLLKLNPEERIGYNDFD---KGYETIKSHPFF |.. ||| ||. . .|.||||. . | ..| ... .|||||.|||. .||.|.|... | ||.| ||.||.| YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF |
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Kinase | 92921.m00274.AA | PDK1 | 35-297 | 38 | 8.99999999999e-119 | 365.61 | In-house | 1-307 (307) | Show / Hide |
Range on Protein: 35-297 Range on HMM: 1-307/307 Sequence Identity: 38% (118 aa) FNIGKVIGRGAFGEVLKVQDIET----GKYYAMKVLSKSRISREKKINYVILERDAMNALN-----HPNIIRLYLTFQDNSNLYYVVELADNGDLQHVLN | .||.||.|....| .. ..|| .| || |...|. | ||||. ||. |...|. || ||.|..|| ||||...||.| |.. |||| | .. FIFGKNIGEGSYSTVYLAREKETKNDENKMYAIKICEKRYIIREKKVKYVHREKEIMCHLNNECNGHPGIVKLYFTFQDEQCLYFVLEYCPNGDLLHYMK Q--YVSLDIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDHNNSVKITDFGTA---KMYKR-----------------------DEPFYSQHGSLV . |.|. .. .|..|| |.| . |||||.|||||||| .. ..||||||| | .|. .. .| | KQPFGSFDMDCCRFYAAEIIDALEHLHSNGIIHRDLKPENILLDKDMHIMITDFGTAGFDKILPEYQSQQQNQFQQQFQQHNKGMDKPEEDKQTRCKSFV GSPDYVSPETLNETPISAATDLWSFGCLVYQFFTGYAPFHTS-----SNYETFQKIESGKYTIPDF--VPADAKDLITKLLKLNPEERIGYNDFDKGYET | ||||| |.. ... ..|.|..||..||...| || . . | ||||| |..|| .| .||||. |||...| .|.. | ||.. GTAEYVSPELLTDKECTPSCDIWALGCIIYQMVAGQPPFRGMNDATNNEYHTFQKIMKCQYDFPDNFRFPPCAKDLVKKLLVRDPNDRLTSCDECGGYQQ IKSHPFF || |||| IKAHPFF |
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Kinase | 92921.m00274.AA | S_TKc | 35-297 | 32 | 7.3e-100 | 338.98 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 35-297 Range on HMM: 1-231/231 Sequence Identity: 32% (89 aa) FNIGKVIGRGAFGEVLKVQDIETGKYYAMKVLSKSRISREKKINYVILERDAMNALNHPNIIRLYLTFQDNSNLYYVVELADN--GDLQHVLNQYVS--- . |...||.||||.| |.....||...|.|... . .. |.. . .||||..|| .||| ..|| | |..|. ||| ... .. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL ---LDIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDHNNSVKITDFGTAKMYKRDEPFYSQHGSLVGSPDYVSPETLNETPISA-ATDLWSFGCL .. |. .. ||..||...|...|||||.||||||||. .||.||| |. . ...|.|.|..|| | . . . | ||.||. RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI VYQFFTGYAPFHTSSNYETFQKIESGKYTIPDFVPADAKDLITKLLKLNPEERIGYNDFDKGYETIKSHPFF .| ...|| ||. ...|.|| . .|||.| |.|. .||.|.. . .. . ||.||.| LYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 92921.m00274.AA | Pkinase | 35-297 | 28 | 4e-89 | 307.2 | Pfam | 1-293 (293) | Show / Hide |
Range on Protein: 35-297 Range on HMM: 1-293/293 Sequence Identity: 28% (88 aa) FNIGKVIGRGAFGEVLKVQDIETGKYYAMKVLSKSRISREKKINYVI-LERDAMNALNHPNIIRLYLTFQDNSNLYYVVELADNG----DLQHVLN--QY . ||..||.|.||.| | ... ||| .|.|...|.... .|... . | |. ||||||.||| .|.|....| | |....| || ... .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH VSL--DIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDHNNSV----KITDFGTAKMYKRDEPFYSQHGSLVGSPDYVSPETLN-ETPISAATDLW .. . .| .. ||| .|...|...|||||.||||||.|.|. . ||.||| || .. . .| ...|.|.|..|| .. .... . | | GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW SFGCLVYQFFTGYAPFHTS------SNYETFQKIESGKYTIPDFVP---------------------ADAKDLITKLLKLNPEERIGYNDFDKGYETIKS |.||..|....|. || . . .. ...| .... . . . ..||.|...|...|..|.. | |. SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT-------AEQILQ HPFF ||.| HPWF |
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Kinase | 92921.m00274.AA | CAMK | 40-297 | 21 | 1.6e-83 | 268.86 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 40-297 Range on HMM: 1-425/425 Sequence Identity: 21% (92 aa) VIGRGAFGEVLKVQDIETG------------KYYAMKVLSKSRIS-------------------------REKKINYVILERDAMNA-------LNHPNI ..|||.||.| ......|. . .|.|...|.... |.|. | | . |. |.|||| TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI IRLYLTFQD-------------------NSNLYYVV---ELADNG----DLQHVLNQY---------------VSLDIPIAKQILGQILLALAHMHQRRI |.|| ...| ....| | |....| || . . .. |... ||. |....|.. | IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI IHRDIKPENILLDHN-----------------NSVKITDFGTAKMYKRD------------EPFYSQ----------HGSLVGSPDYVS-PETLN----- .|||.||||||||.| | .||.||| |...... | . .. .|.| |.. || || VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC ---------ETPISAATDLWSFGCLVYQFFTGYAPFHTS-------------SNYETFQKIESGKYT-IPDFVPA-----------------------DA ..... ..| || |.. | .|| || . . ||.|.|| .|||. .|.... .. NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC KDLITKLLKLNPEERIGYNDFDKGYETIKSHPFF |||| |.|. .||.|. . ...||.. KDLIRKMLQVDPEKRMTIEQ-------CLNHPWM |
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Kinase | 92921.m00274.AA | Ciliate-E2 | 35-297 | 26 | 4e-83 | 282.45 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 35-297 Range on HMM: 1-365/365 Sequence Identity: 26% (101 aa) FNIGKVIGRGAFG-----EVLKVQDIE------------------TGKYYAMKVLSKSRISREKKINYVI----------LERDAMNALNHPNIIRLYLT ... |.||.|.|| .| ||| . ..|.||||...|. | |...... |. . |||||||..| . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC FQ--DNSNLYYVVELADNGDLQHVLN------------QYVSLDIPIAKQILGQILL---------------ALAHMHQRR-IIHRDIKPENILLDHNNS || |..|.|.| |... |||.. .. . .... .|.| ||| || ..|.. ||||||||||||. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKD-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----- VKITDFGTAKMYKRDEP---------FYSQHGS--------------------LVGSPDYVSPETLNETP---------ISAATDLWSFGCLVYQFFTGY .||.|||..| |. |. | . .. ..|.| |..|| || . . . |.||.|.. |.. .|. IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK APFHTSSNYETFQKIESGKYTIPDF------------------VPADAKDLITK----LLKLNPEERIGYNDFDKGYETIKSHPFF || .|.|. .|. .| . .. ..|||| | .|. .||.||. |.| |. ||.| PPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT------GWEQILNHPWF |
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Kinase | 92921.m00274.AA | RSK | 38-297 | 33 | 2e-78 | 266.84 | In-house | 1-278 (278) | Show / Hide |
Range on Protein: 38-297 Range on HMM: 1-278/278 Sequence Identity: 33% (94 aa) GKVIGRGAFGEVLKVQDI---ETGKYYAMKVLSKSRISREKK-INYVILERDAMNALN-HPNIIRLYLTFQDNSNLYYVVELADNGDLQHVLNQYVS--- || |.|..|.| .. . ||..||||||.|. | . .| . .. ||. . . . ||.|..|. .||... || . |. |.| | . .. LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC LDIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDH---NNSVKITDFGTAKMYKRD--EPFYSQHGSLVGSPDYVSPETLN----ETPISAATDLW .. |.... .| ||. |.||. |||||.||||||.|. . ..|.|||| .| . | .. .. ... .|. || |. . ..| |.| FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT----FCYTIEYMAPEMLKRANQQGGHDKACDWW SFGCLVYQFFTGYAPFHT---SSNYETFQKIESGK--YTIP--DFVPADAKDLITKLLKLNPEERIGYNDFDKGYETIKSHPFF |.|.| | .||. ||. .. |....|..|| |.| ... ..|||||.|.|. .|. |.|.. .. | ||.||.| SLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCG--PQDAEEIKQHPWF |
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Kinase | 92921.m00274.AA | Ciliate-E2-Unclassified | 35-297 | 27 | 7.4e-75 | 255.01 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 35-297 Range on HMM: 1-352/352 Sequence Identity: 27% (98 aa) FNIGKVIGRGAFGEVLKVQDIETGKYYAMKVLSKSRISREKKINYV---ILERDAMNALN-------------------HPNIIRLYLTFQDNSNLYYVV ..|.|.||.|.||.| |.|......||||| ..|..| |.|... ..| ..|| .. ||.|.... .||| |.| | YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM ELADNGDLQHVLNQY-----------------VSLDIPIAK-----QILGQILLALAHMHQR-RIIHRDIKPENILLDHNN---SVKITDFGTAKMYKRD |....|||. .... .. || ... |||..| ..|. ||||||||||||.| |. .||.||| .| |. . EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN EPFYSQHG-------------SLVGSPDYV----SPETLNETPIS----AATDLWSFGCLVYQFFTGYAPF-HTSSNY---------------ETFQKIE . .. . . .|.| | .|| | . . . | ||.|.. |.. .|| || .... . .|.| NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK SGKYT--------IPDFVPADAKDLIT----KLLKLNPEERIGYNDFDKGYETIKSHPFF ... ||. .. |||.|. |.|| ||..|| ..| |. ||.| QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI-------TFEQILNHPWF |
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Kinase | 92921.m00274.AA | CAMKL | 35-297 | 27 | 1.5e-73 | 234.02 | In-house | 1-297 (297) | Show / Hide |
Range on Protein: 35-297 Range on HMM: 1-297/297 Sequence Identity: 27% (86 aa) FNIGKVIGRGAFGEVLKVQD-IETGKYYAMKVLSKSRIS-REKKINY-----------VILERDAMNALN---HPNIIRLYLTFQDNSN------LYYVV ..|||..|.|.||.| .. . ||. .|.|.. |..|. .... . . | | || |||||.|| .... .. .| | YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM ELADNGD--LQHVL--NQYVS--LDIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDHNNS--VKITDFGTAKMYKR-----DEPFYSQHGSLVGS |....|. |.. . . .. .. . |... ||. |....|...|.||||||||||||.|.. .||.||| . ||.. .. . . || EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTF----CGS PDYVSPETLNE--T-PISAATDLWSFGCLVYQFFTGYAPFHTSS---------NYETFQKIESGKYTIPDFVPADAKDLITKLLKLNPEERIGYNDFDKG | | .|| .. . . ..| || | . | .|| || . ... ... ....|. .|. |..||| |.|. |||.|. PPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRP-------T YETIKSHPFF . |..||.. IHQIMNHPWM |
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Kinase | 92921.m00274.AA | AktR | 35-297 | 38 | 1e-71 | 244.58 | In-house | 1-268 (268) | Show / Hide |
Range on Protein: 35-297 Range on HMM: 1-268/268 Sequence Identity: 38% (106 aa) FNIGKVIGRGAFGEVLKVQDI-ETGKYYAMKVLSKSRISREKKINYVILERDAMN-ALNHPNIIRLYLTFQDNSNLYYVVELADNGDLQHVLNQYVSLDI | . |..|.||||.| ||. ...|.||||...|. | ..... ..|.||. | ||| |..|. .||....|... | .|.| ..|.. .. FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE PIAKQILGQILLALAHMHQR-RIIHRDIKPENILLDHNNSVKITDFGTAK---MYKRDEPFYSQHGSLVGSPDYVSPETLNE-TPISAATDLWSFGCLVY |. . |||||| . ||. || ||.|||||||| . ||||||| .| | .||. | |..|.| |..||.... . . |.|.||...| EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAY----SFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIY QFFTGYAPFHTSSNYETFQKIESGK-YTIPDFVPA--DAKDLIT-KLLKLNPEERIGYNDFDKGYETIKSHPFF ||. || ... . |||| . .|. .. .||||. |||. ||..|.|| ...| | |||||.| EMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGY--YCNGWEEIKSHPWF |
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Kinase | 92921.m00274.AA | PKA | 35-297 | 36 | 1.4e-66 | 227.46 | In-house | 1-263 (263) | Show / Hide |
Range on Protein: 35-297 Range on HMM: 1-263/263 Sequence Identity: 36% (99 aa) FNIGKVIGRGAFGEVLKVQDIETGKYYAMKVLSKSRISREKKINYVILERDAMNALNHPNIIR-LYLTFQDNSNLYYVVELADNGDLQHVLNQYVSLDIP |.| ...|.| || | ... ..|.|||||.|.|..| |.| . |. |. .....||.|.. .| ||||...||.| |.. |.... | ... | FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP IAKQILG-QILLALAHMHQRRIIHRDIKPENILLDHNNSVKITDFGTAKMYKRDEPFYSQHGSLVGSPDYVSPETLNET-PISAATDLWSFGCLVYQFFT .|| . || ||| .|. ||.|| ||||||.| | .|||||| || . . . .| | |.| || .. . . . | |..|.|.| . . HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTW-----TLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLA GYAPFHTS--SNYETFQKIESGKYTIPDFVPADA---KDLITKLLKLNPEERIGYNDFDKGYETIKSHPFF || || . . ....|| .||. | .. || |||| ||| ....|.| .. | . || |..| GYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKN--GVNDIKNHKWF |
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Kinase | 92921.m00274.AA | Aur | 35-178 | 39 | 1e-52 | 137.12 | In-house | 1-147 (257) | Show / Hide |
Range on Protein: 35-178 Range on HMM: 1-147/257 Sequence Identity: 39% (58 aa) FNIGKVIGRGAFGEVLKVQDIETGKYYAMKVLSKSRISREKKINYVILERDAMNALNHPNIIRLYLTFQDNSNLYYVVELADNGDLQHVLNQY--VSLDI | ||| |.|.||.| ... .|.. .|.||..|. | .. . .. | .. ||||||...| |.|. . | . | | .|.| ..| . ..| FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE PIAKQILGQILLALAHMHQRRIIHRDIKPENILLD-HNNSVKITDFG ..| . || .|| ..| . |||||||||||||| .|. .|| ||| QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFG |
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Kinase | 92921.m00274.AA | Aur | 201-297 | 28 | 2.8e-30 | 76.66 | In-house | 166-257 (257) | Show / Hide |
Range on Protein: 201-297 Range on HMM: 166-257/257 Sequence Identity: 28% (28 aa) DYVSPETLNETPISAATDLWSFGCLVYQFFTGYAPFHT-SSNYETFQKIE-SGKYTIPDFVPADAKDLITKLLKLNPEERIGYNDFDKGYETIKSHPFF ||..|| .. . |.|..| | | . .|..|| .. ||...| .....|.... .||||| |.|. .|..|. .. |..||.. DYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPPFESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQ-------IMNHPWI |
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Kinase | 92921.m00274.AA | Pkinase_Tyr | 35-251 | 29 | 3.7e-19 | 65.5 | Pfam | 1-232 (270) | Show / Hide |
Range on Protein: 35-251 Range on HMM: 1-232/270 Sequence Identity: 29% (72 aa) FNIGKVIGRGAFGEVLKVQDIETGKYY----------AMKVLSKSRISREKK--INYVILERDAMNAL-NHPNIIRLYLTFQ-DNSN--LYYVVELADNG .||..|.|||||| | |... | |.| | . .. . . | | | .||||.||| . .| |.|.. .| ITFGKKLGEGAFGEVYK------GTWKGDPDNTKIPVAVKML-KE-GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHG DLQHVLNQY----VSLDIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDHNNSVKITDFGTAKMYKRDEPFY-SQHGSLVGSPDYVSPETLNETPI || . | . .|... |. || .... .....||||. |.|...|| |||.||| |. .. | ..|. .|| .|. DLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKF SAATDLWSFGCLVYQFFT-GYAP-FHTSSNYETFQKI-ESG . ..| |||| | . || | | . ||.| ...| |.| TTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG |
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Kinase | 92921.m00274.AA | TyrKc | 35-291 | 24 | 3.6e-16 | 38.8 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 35-291 Range on HMM: 1-280/280 Sequence Identity: 24% (72 aa) FNIGKVIGRGAFGEVLKVQDIETGKYY---AMKVLSKSRISREKKINYVILERDAMNAL--NHPNIIRLYLTFQDN-------SNLYYVVELADNGDLQH ||..|.|||||| | |... | |.| .. . . | | | .||||.||| . |. |.|....|||.. ITLGKKLGEGAFGEVYK------GTWKIQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD VLNQYVS-LDIPIAKQILGQILLALAHMHQRRIIHRDIKPENILLDHNNSVKITDFGTAKMYKRD------EPFYSQ----HGSLVGSPDYVSPETLNET | . | . .. || .. |....||||. |.|...|. |||.||| .. . | . |.. .| . .||..|. YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG PISAATDLWSFGCLVYQFFT-GYAPFHT-----SSNYETFQKIESGKYTIPDFV---------PADAKDLITKLLKLNPEERIGYNDFDKGYETI . ..| |||| . . || | | ||.| ......|.. . |.. ..... . .||.| .. .| . KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI---HECF |
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PH | 92921.m00274.AA | PH | 342-428 | 27 | 4.1e-05 | 24.23 | SMART | 1-82 (82) | Show / Hide |
Range on Protein: 342-428 Range on HMM: 1-82/82 Sequence Identity: 27% (25 aa) VIKEGMVVFES---KQRMLVLLEPPKLLICNIDLTQIKKNIPLSNIASVSIQGNELVLVNGLTNAKYEITCDSD-DIQLWLSAIKESISSK ||||| . | |.| .|| . |... . |. ||||.. .|. . .. |.. |.|. . | |..||.. |.. VIKEGWLYKKSKRWKKRWFVLFN-DCLYYYKDK--KPKGSIPLSDC-TVRE-P--CFEIHH-DR-TYYFQCESEEEMQEWMQAIQKAIHNN |