Gene 94680.m00106 (T.vaginalis)

94680.m00106

Species: T.vaginalis
Alias: 94680.m00106, TvagK0247
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Tvag1

Sequence

Name Sequence Type Origin Length Description Download
94680.m00106.AA Protein None 322 None Fasta, JSON
94680.m00106.kin_dom Protein Kinase Domain None 244 None Fasta, JSON

Protein domain

Protein domains of 94680.m00106.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 94680.m00106.AA Ciliate-E2-Unclassified 14-257 19 9.7e-30 100.35 In-house 1-352 (352) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-352/352
Sequence Identity: 19% (69 aa)

FKYNSTIAEGCFGSLLLIYSPKTQLNYCLKRIH------ESRFNQTDLQYIEKIEDTPEIE-----------------------LYTYYKFQDY--VYIL
.| . .| .|.||.  . .  |... | .| ..          .. | ... ...   ...                       .. .| |||.  .|| 
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

QDYS------------------PNDIYFLLKKQAEFTDDQLM-----KYCHEILLTVKQYHDEN-MSQNDIRPTNFVFDKFG---RIRVSSMTINASSED
 .|                    ||..  .|.. .||. |       .|. .||.  ...| .|     || | | .||. |   .|...   |   ...
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

F----------------HSSPSHTGTMLFM----APEVFRKKSYDP---LKSDIWSIGVTFYCMATKNYPYYATNLNT----------------FLKILN
.                . . . .||  .|    ||||.... ||     |.|||| || .|.| . .||.|..| .                 .... .
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

TGIYPVFTVEN--------TELRNIII----KCLDFDPNNRPAVTEILSMPYF
 ... ..  ..         |  ..|     |.|. .||.|.   .||  |.|
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase 94680.m00106.AA CAMK 164-257 22 1.5e-23 72.17 In-house 281-425 (425) Show / Hide 
Range on Protein: 164-257
Range on HMM: 281-425/425
Sequence Identity: 22% (32 aa)

GTMLFMA-PEVFRK-------------KSYDPLKSDIWSIGVTFYCMATKNYPYYA--------------TNLNTFLKILNTGIY-PVFTVEN-------
||  .|| |||...             | |.. |.|.||.||  | | .  .|.|.              .  ..| ||..   . | . . .       
GTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGP

---------------TELRNIIIKCLDFDPNNRPAVTEILSMPYF
               .| .. | |.|  ||..|. ....|. | .
EWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 94680.m00106.AA S_TKc 14-257 22 2.1e-22 81.68 SMART 1-231 (231) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-231/231
Sequence Identity: 22% (59 aa)

FKYNSTIAEGCFGSLLLIYSPKTQLNYCLKRIHESRFNQTDLQYIEKIEDTPEI-ELYTYYKFQDYVYILQDYSPN---DIYFLLKKQAE------FTDD
..   .| .| ||.  . .  ||.  . .|.|.  .  .  .|  .|  . | |  || ..   |..|.  .| ..   | . ..||.        |.  
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-

QLMKYCHEILLTVKQYHDENMSQNDIRPTNFVFDKFGRIRVS----SMTINASSEDFHSSPSHTGTMLFMAPEVFRKKSYDPLKSDIWSIGVTFYCMATK
.  .|...|.. ..  |. .    |. | |  .|.  .| ..    .  .           .  ||  .|||||.   .|.. |.|.||.|...| |.. 
HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCG

NYPYYATNLNTFLKILNTGIYPVFTVENTELRNIIIKCLDFDPNNRPAVTEILS-------MPYF
  |..  .... .|..             |....| |||..||..|| . |.|        .|.|
YPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 94680.m00106.AA MARK 164-257 36 1.2e-21 67.64 In-house 167-262 (262) Show / Hide 
Range on Protein: 164-257
Range on HMM: 167-262/262
Sequence Identity: 36% (35 aa)

GTMLFMAPEVFRKKSYDPLKSDIWSIGVTFYCMATKNYPYYATN--LNTFLKILNTGIYPVFTVENTELRNIIIKCLDFDPNNRPAVTEILSMPYF
||  .||||.| || ||  | |||| ||  | | . ..|. ...  ...  |  ..| |....   .|.||.| . | ..|. || ..||.. | .
GTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase 94680.m00106.AA Pkinase 163-257 26 3.7e-21 75.91 Pfam 172-293 (293) Show / Hide 
Range on Protein: 163-257
Range on HMM: 172-293/293
Sequence Identity: 26% (32 aa)

TGTMLFMAPEVFRKKSYDPLKSDIWSIGVTFYCMATKNYPYYAT----NLNTFLKILNTGIYPVFTVEN-----------------------TELRNIII
.||  .||||| |. .|.. |.|.||.|...|.|.... |..      |..   .| ...  |.   .                         |.. .| 
CGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIK

KCLDFDPNNRPAVTEILSMPYF
.||..||. ||  ..||  |.|
WCLCKDPKKRPTAEQILQHPWF
Kinase 94680.m00106.AA Ciliate-E2 14-257 16 6.6e-21 68.49 In-house 1-365 (365) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-365/365
Sequence Identity: 16% (63 aa)

FKYNSTIAEGCFGSLLLI--YSPKTQLN---------------------YCLKRIHESRFNQTD--LQYIEKIEDTP-----------------EIELYT
.| .  | .|.|||  .   .. . | .                     | .|.....  .|.   .. . .|..                    |..| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINC-FYKKINEKNILEQLNHPNIIKMYE

YYK--FQDYVYILQDYSPN-DIYFLLK------------------KQAEFTDDQLMK--------YCHEILLTVKQYHDEN-MSQNDIRPTNFVFDKFGR
...   ....|.  .|    | . ..|                  |.. .   |. .        |. .|.| ..  | .|     || | | .|     
CFQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----

IRVSSMTINASSEDFHSSPSH--------------------------------TGTMLFMAPEVFRKKSYDP--------LKSDIWSIGVTFYCMATKNY
| .. . .     |..   .|                                 ||  .||||....|.||          |.||||.||..|.| ....
IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PYYATNLNTFLKILNTGIYPVFTVENT------------------ELRNIIIK----CLDFDPNNRPA-VTEILSMPYF
|.        ...   . .  .  |..                  |  ..| |    .|. ||..|.    .||  |.|
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 94680.m00106.AA CAMKL 164-257 30 7.2e-21 63.2 In-house 195-297 (297) Show / Hide 
Range on Protein: 164-257
Range on HMM: 195-297/297
Sequence Identity: 30% (32 aa)

GTMLFMAPEVFRK--KSYDPLKSDIWSIGVTFYCMATKNYPYYATNL--------NTFLKILNTGIYP-VFTVENTELRNIIIKCLDFDPNNRPAVTEIL
|.  .||||.| .  |.||  | ||||.||. | | . ..|  . ..        . ..||  .  || ..     ..|..| | |  .|. || . .|.
GSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIM

SMPYF
. | .
NHPWM
Kinase 94680.m00106.AA CAMKK-Unclassified 164-257 28 2.6e-19 59.28 In-house 267-392 (392) Show / Hide 
Range on Protein: 164-257
Range on HMM: 267-392/392
Sequence Identity: 28% (36 aa)

GTMLFMAPEVFRKK--SYDPLK-------------------------SDIWSIGVTFYCMATKNYPYYATNLN-TFL-KILNTG-IYPV--FTVENTELR
||  |||||.. |.   ||..                           |||| |||||||...  |....||.  |  .|..     |    .  . |. 
GTYCFMAPEFWSKENFKYDYNDYSFLPGTFNPLRKTYRIERICFYKKADIWSLGVTFYCMVYHSLPFWHKNLQELFHQMICQKEINFPPQYHPHCSHEFK

NIIIKCLDFDPNNRPAVTEILSMPYF
. | |..| .|  |  .. .|  |.|
DLIQKMCDKNPKKRITIDQMLVHPWF
Kinase 94680.m00106.AA CAMKK 164-257 24 1.7e-18 54.88 In-house 272-396 (396) Show / Hide 
Range on Protein: 164-257
Range on HMM: 272-396/396
Sequence Identity: 24% (31 aa)

GTMLFMAPEVFRK-KS--------------YDPLKSDIWSIGVTFYCMATKNYPYYATN-LNTFL---KILNTGI-YPVF-----------TVENTELRN
||  |||||...| ..              |.  . |||. |||.||. ... |....| . ..    ||.|  | .| .             ....| .
GTPAFMAPELCSKENQKENYNGYKYRFRFIYCGKAADIWALGVTLYCFVFGKCPFWHNNLMQLHHNYMKIKNDPIKFPENKEMLNNVSIYCPEISEDLKD

IIIKCLDFDPNNRPAVTEILSMPYF
.| ..|. .|  |  ...|.. | .
LIKRMLEKNPTKRITIPQIKVHPWV
Kinase 94680.m00106.AA NEK 161-257 33 3.8e-18 60.81 In-house 182-286 (286) Show / Hide 
Range on Protein: 161-257
Range on HMM: 182-286/286
Sequence Identity: 33% (36 aa)

S-HTGTMLFMAPEVFRKKSYDPLKSDIWSIGVTFYCMATK--NYPYYAT--NLNTFLKILNTG-IYPVFT-V--ENTELRNIIIKCLDFDPNNRPAVTEI
. ..||  .|.|||.. |.|.  ||||||.|.  | |.|   . | .|.  |..   .    |  ||         ..|.|.| ..|  || .|| ...|
TTQVGTPYYMSPEVCQNKPYNN-KSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQI

LSMPYF
|.||. 
LEMPFI
Kinase 94680.m00106.AA STE 161-257 25 4.6e-18 60.47 In-house 222-359 (359) Show / Hide 
Range on Protein: 161-257
Range on HMM: 222-359/359
Sequence Identity: 25% (36 aa)

SHTGTMLFMAPEVFRK------KSYDPLKSDIWSIGVTFYCMATKNYPYYA-TNL-NTFLKILNTGIY-----------PVFTVEN--------------
. .||  .||||| ..      | ||  |.||||.| |   ||| ..|.   ... . |... |....           |  . ..              
TFVGTP-WMAPEVIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSG

--------TELRNIIIKCLDFDPNNRPAVTEILS--MPYF
         |... | |||. |||.|| ... |.   | .
TTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 94680.m00106.AA NEK4 164-257 33 1.8e-17 59.47 In-house 164-257 (257) Show / Hide 
Range on Protein: 164-257
Range on HMM: 164-257/257
Sequence Identity: 33% (32 aa)

GTMLFMAPEVFRKKSYDPLKSDIWSIGVTFYCMATKNYPYYATNLNTFL-KILNTGIYPVFTVENTELRNIIIKCLDFDPNNRPAVTEILSMPYF
||  .| ||.|  . ||  ||||||.|   | |.|    . | ..|  . .|..    |.  .  ..| |.. . |.  |..|| . .|. ||| 
GTPYYMSPECFGNRPYD-YKSDIWSLGCCVYEMITLKHAFDAKDMNSLIYQIIQGQPPPMPPNYSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase 94680.m00106.AA TyrKc 14-257 17 3.8e-05 -139.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 14-257
Range on HMM: 1-280/280
Sequence Identity: 17% (50 aa)

FKYNSTIAEGCFGSLLL-IYSPKTQLNYCL---KRIHESRFNQTDL----QYIEKI--EDTPEIELYTYYKFQ-------DYVYILQDYSPNDI---YFL
 . . .. ||.||   . ...            | ..|.   . |.    .   |.  .    . || .   |       . ..|.  | |.      .|
ITLGKKLGEGAFGEVYKGTWK-------IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPH-GDLKDYL

LKKQAEFTDDQLMKYCHEILLTVKQYHDENMSQNDIRPTNFVFDKFGRIRVS--SMTINASSE-------DFHSS----PSHT-GTMLFMAPEVFRKKSY
 |.. ... ..| ..|. |       |. |    |.   |   .. .....|   .. .  ..       |  ..     ..|      ||||..... .
RKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

DPLKSDIWSIGVTFYCMATKNYPYYA------TNLNTFLKILNTGIYPVFTVE---------NTELRNIIIKCLDFDPNNRPAVTEILSMPYF
 . |||.|| ||. . . |   . |        .    .. . .| ..    .          .|. .|. .| ..||..||  .||    .|
TT-KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase 94680.m00106.AA Pkinase 67-117 16 8.03449 0.45 Pfam 63-122 (293) Show / Hide 
Range on Protein: 67-117
Range on HMM: 63-122/293
Sequence Identity: 16% (10 aa)

IELYTYYKFQDYVYILQDYSPN-----DIYFLLK--KQAEF--TDDQLMKYCHEILLTVK
..|| ..   |..|. ..| ..     | . ...  ..  |  ..... .|. .||  ..
VRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLE