Gene 90756.m00165 (T.vaginalis)

90756.m00165

Species: T.vaginalis
Alias: 90756.m00165, TvagK0410
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
90756.m00165.AA Protein None 650 None Fasta, JSON
90756.m00165.kin_dom Protein Kinase Domain None 274 None Fasta, JSON

Protein domain

Protein domains of 90756.m00165.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 90756.m00165.AA AGC 298-571 27 6.9e-117 303.29 In-house 1-395 (395) Show / Hide 
Range on Protein: 298-571
Range on HMM: 1-395/395
Sequence Identity: 27% (109 aa)

FKIIAPISRGAYGSVFLCQRI------QTGDVFALKVIPADD---LSMKNDVLDT--E------------REVMCRAL----------HPSTIS-LFWSF
|... .|..|..| |.|...       .||...|.||.  ..   . .||.|  |  |            |... ..           ||  .. |. ||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

RASST--VFFVMSFAR---------GG-DLYALLE---SVGSLDEEVAAFYVAE-------LVLAIEYIHS-LNVVHCD-LKPDNILINDSGHLQLTDFG
   .   ..||| ..          || .|.  |      |..|||.| || ||       .|||.||.|| ....| | |||.|||... ||. |||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSKFGLEQ----------------------------RELGRSLMFRFAPSSATKSDTNDHK-----RRVIG--TPHYISPESLLRSDYSPKVDWWA--LG
|.| |                               . .... . | . .| . .||.  |         |  ||.|..|| |    |.. .|||.  ||
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNK-CNPNNWQRNN-MSQE-DDTTR-KKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLG

VIAYELVVGEPPFGGNS----------EAEIFSHIVAG------KYEWP--------DDVEVSDEYKKFVHDLLNLNPEKRPD----------AEELKKY
.. ||...| ||| |..          ..|.|  |  |      | ..|        .|...|.| | ..  ||. .||||.           |||.|. 
CLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNH

KIF
. |
PWF
Kinase 90756.m00165.AA MAST 298-571 32 1.5e-95 308.47 In-house 1-334 (334) Show / Hide 
Range on Protein: 298-571
Range on HMM: 1-334/334
Sequence Identity: 32% (109 aa)

FKIIAPISRGAYGSVFLCQRIQTGDVFALKVIPADDLSMK--NDVLDTEREVMCRALHPSTISLFWSFRASSTVFFVMSFARGGDLYALLESVGSLDEEV
|..| |||.|||| |.|   . |.| ||.|||  .|.  |   | . .|| .   .  | . ..| ||   . ...|| .  |||.  ||...|..||. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

AAFYVAELVLAIEYIHSLNVVHCDLKPDNILINDSGHLQLTDFGLSKFGLEQRELGRSLM--------FRFAPSSATKSDTND-----------------
| .|.||.||..||.||   ||.||||||.||  .||  ||||||||.|. ..   .           . . | .  . |.                   
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

-------------------HKRRVIGTPHYISPESLLRSD-YSPKVDWWALGVIAYELVVGEPPFGGNSEAEIFSHIVAGK---YEWPDD------VEVS
                    . ...||| ||.|| .|. . ... ||||..|.| ||. || ||| . .  |||..|.  .    |||..       . |
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

DEYKKFVHDLLNLNPEKRPDAE----ELKKYKIF
 | .  .  ||...|.||. |     | |. . |
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase 90756.m00165.AA MAST 298-571 32 7.7e-94 287.04 In-house 1-337 (337) Show / Hide 
Range on Protein: 298-571
Range on HMM: 1-337/337
Sequence Identity: 32% (109 aa)

FKIIAPISRGAYGSVFLCQRIQTGDVFALKVIPADDLSMK--NDVLDTEREVMCRALHPSTISLFWSFRA--SSTVFFVMSFARGGDLYALLESVG-SLD
|..| .||.|||| |.| . . |.| ||.|||  .|.  |   | .  || .   .  |.. ..| ||       ...|| .  |||   ||...| ...
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EEVAAFYVAELVLAIEYIHSLNVVHCDLKPDNILINDSGHLQLTDFGLSKFGLEQRELGRSLMFRFAPS---------SATKSDTNDH------------
|. | .|.||.||..||.||   ||.||||||.||   ||. ||||||||.|. .. . .     |..          . .. ...              
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDK-TTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNK

-------------------------KRRVIGTPHYISPESLLRSD-YSPKVDWWALGVIAYELVVGEPPFGGNSEAE-IFSHIVA--GKYEWPDD-----
                         . ...||| ||.|| .|.   |.. ||||..|.| ||. ||.||| | .  | ||..|.    . |||..     
NQIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPND

-VEVSDEYKKFVHDLLNLNPEKRPDAE---ELKKYKIF
  ..|.| .  .  ||..|| ||  |    | |. . |
DDCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF
Kinase 90756.m00165.AA S_TKc 298-571 27 5e-84 286.37 SMART 1-231 (231) Show / Hide 
Range on Protein: 298-571
Range on HMM: 1-231/231
Sequence Identity: 27% (81 aa)

FKIIAPISRGAYGSVFLCQRIQTGDVFALKVIPADDLSMKNDVLDTEREVMCRALHPSTISLFWSFRASSTVFFVMSFARG--GDLYALLESVGS-----
..|. .| .||.|.|..|. . || ..|.|.|.        . .  |.... .  ||  . |. .|.  . ...|| .. |  |||. .... |.     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

-LDEEVAAFYVAELVLAIEYIHSLNVVHCDLKPDNILINDSGHLQLTDFGLSKFGLEQRELGRSLMFRFAPSSATKSDTNDHKRRVIGTPHYISPESLLR
 ..| .|.||......|.||.||....|.||||.|||...  |. ..||||...                             . ..|||.|..|| |  
PFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------------------TTFCGTPWYMAPEVL--

SDYSP-KVDWWALGVIAYELVVGEPPFGGNSEAEIFSHIVAGKYEWPDDVEVSDEYKKFVHDLLNLNPEKRPDAEELKK-------YKIF
  |.. |.|||..|.| ||...|.|||    ....| .|.            |.| | |.  .|. .||||| | |. .          |
-GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 90756.m00165.AA NDR 298-559 27 7.7e-76 233.22 In-house 1-333 (350) Show / Hide 
Range on Protein: 298-559
Range on HMM: 1-333/350
Sequence Identity: 27% (92 aa)

FKIIAPISRGAYGSVFLCQRIQTGDVFALKVIPADDLSMKNDV--LDTEREVMCRAL--HPSTISLFWSFRASSTVFFVMSFARGGDLYA---LLESVGS
|.|| .|..||.| |.|..   ||...|.|..   . ..|| |  . .||..|  |   .|   .|. ||  ..  ..|| .  |||.     ||   . 
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LDEEVAAFYVAELVLAIEYIHSLNVVHCDLKPDNILINDSGHLQLTDFGLSKFGLE---------------------QR---------ELGRSLMFRFAP
..|..| || ||.|.|||..|... .| |.||||.||.  ||. ||||||.. |..                     ..         |. ..  .... 
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

SSATKSDT--------------NDHKRR------------VIGTPHYISPESLLR-SDYSPKVDWWALGVIAYELVVGEPPFGGNSEAEIFSHIVAGKYE
|. ... .              .....|            ..||| |. || ...   |.. .||| ||.| ||..|| ||| . .  |..  |   |  
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

W-------PDDVEVSDEYKKFVHDLLNLNPEKR
|       | ....|.| .     |.. .|..|
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHR
Kinase 90756.m00165.AA Pkinase 298-571 26 1.1e-71 249.2 Pfam 1-293 (293) Show / Hide 
Range on Protein: 298-571
Range on HMM: 1-293/293
Sequence Identity: 26% (84 aa)

FKIIAPISRGAYGSVFLCQRIQTGDVFALKVIPADDLSMKNDVLDT---EREVMCRALHPSTISLFWSFRASSTVFFVMSFARGG----DLYALLE--SV
..|. .| .|..|.|..|... ||...|.|.|. .. ... |. ..   | ..| |  ||  . |. .|. .. . .|| ...||    ||.....  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GSL--DEEVAAFYVAELVLAIEYIHSLNVVHCDLKPDNILINDSGHL----QLTDFGLSKFGLEQRELGRSLMFRFAPSSATKSDTNDHKRRVIGTPHYI
|..  .|... ||. ... ..||.|| ...|.||||.||||.. ||.     ..||||.|.                         |     . |||.|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--------------------Y-NNS-MTTFCGTPWYM

SPESLL-RSDYSPKVDWWALGVIAYELVVGEPPFGGN------SEAEIFSHIVAGKYEWPDDVEVS-------------------DEYKKFVHDLLNLNP
.|| .. ...|.||||.|..|.| ||.. |.||| |       .. ...  |  ...... . . |                   .| |.|. ..|...|
APEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDP

EKRPDAEELKKYKIF
.||| ||.... . |
KKRPTAEQILQHPWF
Kinase 90756.m00165.AA RSK 301-571 30 1.8e-68 233.77 In-house 1-278 (278) Show / Hide 
Range on Protein: 301-571
Range on HMM: 1-278/278
Sequence Identity: 30% (92 aa)

IAPISRGAYGSVFLCQRI---QTGDVFALKVIPADDLSMKNDVLD-----TEREVMCRAL-HPSTISLFWSFRASSTVFFVMSFARGGDLYALLESVGS-
.    .|.||.||||...   .|| ..| ||.    .  ..   |     |||... |   ||  ..|. .|.  . .. .| . |||.|.  |.  .. 
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQ--KDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHF

--LDEEVAAFYVAELVLAIEYIHSLNVVHCDLKPDNILIND---SGHLQLTDFGLSKFG-LEQRELGRSLMFRFAPSSATKSDTNDHKRRVIGTPHYISP
  ..|. |.|| ||.|||.|..|.. ..| ||||.||| .|   .||. |||||..| . ... ..  .                      ..| .|. |
GCFSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT---------------------FCYTIEYMAP

ESLL----RSDYSPKVDWWALGVIAYELVVGEPPFGG---NSEAEIFSHIVAGK--YEWPDDVEVSDEYKKFVHDLLNLNPEKRPD-----AEELKKYKI
| |     .. ..  .||| |||. ||. .| ||| |   |. .||.  |  ||   . | . ..|.| | ..  .|  .|.||.      |||.|. . 
EMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPW

F
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F
Kinase 90756.m00165.AA CAMK 303-567 20 1.9e-65 209.59 In-house 1-421 (425) Show / Hide 
Range on Protein: 303-567
Range on HMM: 1-421/425
Sequence Identity: 20% (88 aa)

PISRGAYGSVFLCQRIQTG------------DVFALKVIPADDLS-------------------------MKNDVLDTEREVMCRAL---------HPST
 . ||..| |.||....|.              .| |.|. . |.                           .|    .||. .  .         ||  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISLFWSFR------------ASST--------VFFVM---SFARGG----DLYALLESVGS---------------LDEEVAAFYVAELVLAIEYIHSLN
|.|.  .               |.        ...||    .. ||    ||.  . . |.               ..|. |..|.  .. |..|.||.|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VVHCDLKPDNILINDS-----------------GHLQLTDFGLSKFGLEQR-------ELGRSLMFRFAPSSATKSDTNDHKRRVIGTPHYIS-PESLLR
.||.||||.|||..|.                 . . ..|||....  .           |.. | . .    | .....  . . |||.|.. || |..
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQ---WTTPTEGQKMKTFCGTPEYMAAPEVLNG

--------------SDYSPKVDWWALGVIAYELVVGEPPFGGN-------------SEAEIFSHIVAGKYEWPD--------------DVEVSDE-----
                |.||.| |..||| | ...|.||| |              .. |.|  | .|||..|.              . ..|||     
KGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFV

---YKKFVHDLLNLNPEKRPDAEELKK
    | ..  .|. .||||. .|. ..
SQECKDLIRKMLQVDPEKRMTIEQCLN
Kinase 90756.m00165.AA Ciliate-E2 298-571 21 1.7e-61 209.9 In-house 1-365 (365) Show / Hide 
Range on Protein: 298-571
Range on HMM: 1-365/365
Sequence Identity: 21% (83 aa)

FKIIAPISRGAYGSVFLCQRIQTGD-----------------------VFALKVIPADDLSMKNDVLD------------TEREVMCRALHPSTISLFWS
.|.|  | .|..|||..|......                         .|.|..  ... ... ...             |.... .  ||  | ....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FR--ASSTVFFVMSFARGGDLYALLESV-----------GSLDEEVAA---------------FYVAELVLAIEYIHSLN-VVHCDLKPDNILINDSGHL
|     .....|| .. ||||. ....            ....|. ..               ||.|...||.||.|| | ..| |.||.|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

QLTDFGLSKFGLEQRELGR------SLMFRFAPSSATKSDTNDHKRRV----------IGTPHYISPESLLRSD---------YSPKVDWWALGVIAYEL
 ..||||||.  .... ..       .|| .   | | ..                  .|||.| .|| | . .         |. |.|.|.|||| ||.
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMD-----QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEM

VVGEPPFGGNSEAEIFSHIVAGKYEWP----------------DDVEVSDEYKKFVHD----LLNLNPEKRPD-AEELKKYKIF
. |.|||        .  |  .|.. |                .  ..|.| | .       .|. .||||.. .|.... ..|
LFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 90756.m00165.AA AktR 298-571 30 1.9e-60 207.14 In-house 1-268 (268) Show / Hide 
Range on Protein: 298-571
Range on HMM: 1-268/268
Sequence Identity: 30% (88 aa)

FKIIAPISRGAYGSVFLCQRI-QTGDVFALKVIPADDLSMKN--DVLDTEREVMC-RALHPSTISLFWSFRASSTVFFVMSFARGGDLYALLESVGSLDE
|...... .||.| |.|.|.  ......|.|.|   ..  .|  ... ||| .|   . ||  . |. .|   .  ||.|.. .||.|.  | . . ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

EVAAFYVAELVLAIEYIHSL-NVVHCDLKPDNILINDSGHLQLTDFGLSKFGLEQRELGRSLMFRFAPSSATKSDTNDHKRRVIGTPHYISPESLLR-SD
|.| || |. .||.|| |.  |..  ||||.|||.   ||. .|||||||                      . . ... . . |||.|..|| ...   
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-------------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKG

YSPKVDWWALGVIAYELVVGEPPFGGNSEAEIFSHIVAGK-YEWPDDVEVSDEYKKFVH-DLLNLNPEKRP-----DAEELKKYKIF
.   |||||.|.  ||.|.| |||  ..  ..|  |      . |. ...|...|...   ||. ||.||.     ..||.|. . |
HNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 90756.m00165.AA MASTL 298-571 31 5.9e-60 203.99 In-house 1-283 (283) Show / Hide 
Range on Protein: 298-571
Range on HMM: 1-283/283
Sequence Identity: 31% (95 aa)

FKIIAPISRGAYGSVFLC-QRIQTGDVFALKVIPADDLSMKNDV--LDTEREVMCRALHPSTISLFWSFRASSTVFFVMSFARGGDLYALLESVGSLDEE
| |. ||||||.| |.|  .  . .  .|.||.   |.  || .    .||. .     .  ..|..|    | |. || .  |||.  ||   |  |||
FVIVKPISRGAFGKVYLGYKNQKGKKLYAVKVMKKADMINKNMTHQVQAERDALALSKSQFCVHLYYSLQSASYVYLVMEYMIGGDVKSLLHMYGYFDEE

VAAFYVAELVLAIEYIHSLNVVHCDLKPDNILINDSGHLQLTDFGLSKFGLEQRELG-RSLMFRFAPSSATKSDTNDHKRRVIGTPHYISPESLLRSDYS
.| .|..|.|.|..|.|   ..| |.||||.||  .||. ||||||||  . .| .. |  |                  ...||| |  || ...    
MAIKYISEMVMALDYLHRHGIIHRDIKPDNMLISNEGHIKLTDFGLSKVTM-NRDINARVSM-----------------MDILGTPDYLKPEQDYQQTHG

PKVDWWA-LGVIAYELVVGEPPFGGNSEAEIFSHIVAGKYEWPDDVEVSD----------------------EYKKFVHDLLNLNPEKRPDAEELKKYKI
. ||||| |||  ||   | |||   |    |  |     |||  .|  .                      . .  .  || ..|. || | . .  . 
QVVDWWASLGVCFYEFMKGIPPFCDESPCKVFQNILSRDLEWPMGDEQKSTTPYSSKLLKSCFETVASNPEVPVMCLIENLLQMRPRDRPSATDVQQHTF

F
 
I
Kinase 90756.m00165.AA PKA 298-442 33 1.3e-37 131.29 In-house 1-149 (263) Show / Hide 
Range on Protein: 298-442
Range on HMM: 1-149/263
Sequence Identity: 33% (50 aa)

FKIIAPISRGAYGSVFLCQRIQTGDVFALKVIPADDLSMKNDV--LDTEREVMCRALHPSTI-SLFWSFRASSTVFFVMSFARGGDLYALLESVGSLDEE
|.||. . .| .| | ||.  ..|. .|.|..  ..    . |    .|. ..    ||  . .. |.|  ..  ..|| .. ||..   |  .|.... 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

VAAFYVA-ELVLAIEYIHSLNVVHCDLKPDNILINDSGHLQLTDFGLSK
.| ||.| . |||.||.||.| .. |||| ||||.. ||...|||| .|
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAK
Kinase 90756.m00165.AA PKA 477-559 33 3.2e-18 66.88 In-house 160-246 (263) Show / Hide 
Range on Protein: 477-559
Range on HMM: 160-246/263
Sequence Identity: 33% (29 aa)

GTPHYISPESLLRS-DYSPKVDWWALGVIAYELVVGEPPFGGN--SEAEIFSHIVAGKYEWPDDVEVSD-EYKKFVHDLLNLNPEKR
||| |. || ....  .   |||||||.. ||...| |||  .  . ..|.  |..||...|  . .     | ..  ||. ...||
GTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPFYDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKR
Kinase 90756.m00165.AA TyrKc 298-571 19 2.3e-13 -6.45 SMART 1-280 (280) Show / Hide 
Range on Protein: 298-571
Range on HMM: 1-280/280
Sequence Identity: 19% (60 aa)

FKIIAPISRGAYGSVFLCQRIQTGDVFALKVIPADDLSMKNDVLDTEREVMCRA--LHPSTISLFWSFRAS-------STVFFVMSFARGGDLYALLESV
 . .  . .||.| |.... .      | |.. .|        .  | ..||.    ||  . |.   . .         .. || .. .|||   | . 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

GS-LDEEVAAFYVAELVLAIEYIHSLNVVHCDLKPDNILINDSGHLQLTDFGLSKFGLEQRELGRSLMFRFAPSSATKSDTNDHKR--RVI--GTPHYIS
.  |  .    .        ||.|| |..| ||   |.|... ..   .|||||... .  . |              .|. ..|              .
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG------------ESKDYYRKKEHKGGKTMLPIRWMA

PESLLRSDYSPKVDWWALGVIAYELV-VGEPPFGG-----NSEAEIFSHIVAGKYEWPDDV-------EVSDEYKKFVHDLLNLNPEKRPDAEELKKYKI
||..  . ...| | |. ||  .|.   |..|  |      | .|.. .. .|..  . .        . .||  .   .  . .||.||  .|.  ...
PECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HEC

F
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