Gene 81312.m00088 (T.vaginalis)

81312.m00088

Species: T.vaginalis
Alias: 81312.m00088, TvagK0363
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
81312.m00088.AA Protein None 716 None Fasta, JSON
81312.m00088.kin_dom Protein Kinase Domain None 263 None Fasta, JSON

Protein domain

Protein domains of 81312.m00088.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81312.m00088.AA AGC 324-586 29 1.5e-133 347.39 In-house 1-395 (395) Show / Hide 
Range on Protein: 324-586
Range on HMM: 1-395/395
Sequence Identity: 29% (117 aa)

FKFVKRISNGAFARVFLATK---------DKLKSPVAIKVIPRRN---VRGKGSTNRLLTE------------KNIMLHFN----------SPYTIR-FF
|.|.| |. |.| .|.|. |         .|.    |.||.  .     . |    . .||            .||. . |          .|. ..  .
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKY---YAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILH

YSTIGKHN--LYMVMEYLP---------GG-DLFSLLE---KFGCFPEDVARNYTAQ-------IVAALEYLRQ-NNVIHRD-LKPDNILLDSAGHLKLV
||   | .  ||.||||.|         || .||. |    | |.|.|..|| |.|.       || ||||| . ...|||| |||.|||||. ||.||.
YSFQDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLT

DFGLSYFGVVG-----------RQTDTHES-------------------------------------TALG--TPDYIAPEIITLENHSYQADYWS--LG
||||.  |. .           . .  |..                                     |  |  ||.|.||||.    .....|.||  ||
DFGLCKEGMNDGEKGQQSQSNMKFHW-HNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLG

AMLYEFITGVAPFHDNTPQ----------EIFSNVL------CGSINFK------ELEEMNASKDCIDFIQKLLVSDPKKRLGAES-------IDEIKHH
...||..||  ||....||          |.| ...         . |       . |. . |... |.|.|||. ||.||||.         ..||| |
CLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNH

PWF
|||
PWF
Kinase 81312.m00088.AA S_TKc 324-586 34 9.4e-97 328.66 SMART 1-231 (231) Show / Hide 
Range on Protein: 324-586
Range on HMM: 1-231/231
Sequence Identity: 34% (95 aa)

FKFVKRISNGAFARVFLATKDKLKSPVAIKVIPRRNVRGKGSTNRLLTEKNIMLHFNSPYTIRFFYSTIGKHNLYMVMEYLPG--GDLFSLLEKFGC---
..... |  |||..|..... | .  ||||.|.          .... | .|. . . |. ......    ..|||||||..|  ||||....| |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FPEDVARNYTAQIVAALEYLRQNNVIHRDLKPDNILLDSAGHLKLVDFGLSYFGVVGRQTDTHESTALGTPDYIAPEIITLENHSY-QADYWSLGAM
   ||| .|| |..||. ||||. ....|||||||.|||||.  |.|. ||||. .           .|  |||.|.|||..    ...  .| ||.| .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LYEFITGVAPFHDNTPQEIFSNVLCGSINFKELEEMNASKDCIDFIQKLLVSDPKKRLGAESIDE----IKHHPWF
|||...|  ||.  ..|..| ...              |....|||.|.|. ||.||..|  . .    || ||||
LYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 81312.m00088.AA SGK 324-586 34 8.1e-85 261.8 In-house 1-283 (283) Show / Hide 
Range on Protein: 324-586
Range on HMM: 1-283/283
Sequence Identity: 34% (101 aa)

FKFVKRISNGAFARVFLATKDKL------------------KSPVAIKVIPRRNVR-------GKGSTNRLLTEK-NIMLHFNSPYTIRFFYSTIGKHNL
|.| | |  | | .|... . .                   .   |.||. .  ..        | . .  ..|. .|.  ...|  .   |.   |  |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

YMVMEYLPGGDLFSLLEKFGCFPEDVARNYTAQIVAALEYLRQNNVIHRDLKPDNILLDSAGHLKLVDFGLSYFGVVGRQTDTHESTALGTPDYIAPEII
|.||.|. ||..|. | . ..||||.|| |.|.|| |||||   ..|.|||||.|||||. ||..| ||||.  |.   .| .  .|  ||| | |||..
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGI---KTNDTTFTFCGTPEYLAPEVL

TLENHSYQADYWSLGAMLYEFITGVAPFHDNTPQEIFSNVLCGSINFKELEEMNASKDCIDFIQKLLVSDPKKRLGAE-SIDEIKHHPWF
  . |.   | |.||. |||...|  || ..  |. . | . . ....     . | |. | || ||  |||||||.     ||| ||.|
RKQPHDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPP----QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 81312.m00088.AA Ciliate-E2 324-586 24 2.3e-80 273.27 In-house 1-365 (365) Show / Hide 
Range on Protein: 324-586
Range on HMM: 1-365/365
Sequence Identity: 24% (92 aa)

FKFVKRISNGAFARVFLATKDKLK-----------------------SPVAIKVIPRRNVRGKGSTNRLL----------TEKNIMLHFNSPYTIRFFYS
.||.| | .|.|. |......| .                       . .|.|..  .... . . ....           ||||. . |.|. |.....
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

TI--GKHNLYMVMEYLPGGDLFSLLEKF-----------GCFPEDVARNYTAQIVA---------------ALEYLRQNN-VIHRDLKPDNILLDSAGHL
 .   ..|.|.||||. |||||......           ..| |  ......||.                ||||| ..| .||||.||.|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLVDFGLSYF-----------GVVGRQTDTHE------------------STALGTPDYIAPEIITLEN---------HSYQADYWSLGAMLYEFITGVA
|..||||| .              .  .. .                    | .||| | ||||.  ..         ..|..|.|||| .|||...|  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFHDNTPQEIFSNVLCGSINFKELE--------------EMNASKDCIDFIQK----LLVSDPKKRLGAESIDEIKHHPWF
||        . . . . |.| . |                . |..|.|.|.|    .|. ||.||..  ....|. ||||
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 81312.m00088.AA Ciliate-E2-Unclassified 324-586 27 4.1e-79 269.13 In-house 1-352 (352) Show / Hide 
Range on Protein: 324-586
Range on HMM: 1-352/352
Sequence Identity: 27% (97 aa)

FKFVKRISNGAFARVFLATKDKLKSPVAIKVIPRRNVRGKGSTNRL---------LTEKN-------------IMLHFNSPYTIRFFYSTIGKHNLYMVM
.|..| | .|.|. |... ..| |   |.| .   ... . . ..          . .|.             |.|....|. ...||    | |.|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYLPGGDLFSLLEKF-----------------GCFPEDVAR-----NYTAQIVAALEYLRQNN-VIHRDLKPDNILLDSAG---HLKLVDFGLSYFGVVG
||..||||.  ..|.                  .|.|  |.     .|.|||. .|||| ..| .||||.||.|||.|. |   ..|. |||.|..    
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

RQTDTHE-------------STALGTPDYI----APEIITLENHS----YQADYWSLGAMLYEFITGVAPFHDNTPQE----------------IFSNVL
.. | ..             .|  ||| |.    |||..  .|..    |..|.||||  |||...|  || ||.  .                ...| .
NNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

CGSINFKELEE----MNASKDCIDFIQ----KLLVSDPKKRLGAESIDEIKHHPWF
 . |.|.. ..    .. |. ..|||.    |.|. .|.||.   ....|. ||||
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI---TFEQILNHPWF
Kinase 81312.m00088.AA Pkinase 324-586 30 3e-78 271.06 Pfam 1-293 (293) Show / Hide 
Range on Protein: 324-586
Range on HMM: 1-293/293
Sequence Identity: 30% (91 aa)

FKFVKRISNGAFARVFLATKDKLKSPVAIKVIPRRNVRGKGSTNRLL-TEKNIMLHFNSPYTIRFFYSTIGKHNLYMVMEYLPGG----DLFSLLE--KF
......|  |.|..|..... .    ||.|.|..|. . .   .... .|  ||...|.|. .|....   | ..||||||..||    |||....  . 
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GCF--PEDVARNYTAQIVAALEYLRQNNVIHRDLKPDNILLDSAGHL----KLVDFGLSYFGVVGRQTDTHESTALGTPDYIAPEIIT-LENHSYQADYW
|||  .|.....|  ||. .|||. ....|||||||.|||.|. ||.    |. ||||. .       ..  .|  |||.|.|||.|   . ... .| |
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMW

SLGAMLYEFITGVAPFHDN------TPQEIFSNVLCGSINFKELEEMNAS-----------------KDCIDFIQKLLVSDPKKRLGAESIDEIKHHPWF
|.| .|||...|  || .       ...... ..... . | . .. . |                 ..|.||| ..|  |||||..   ...|..||||
SCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT---AEQILQHPWF
Kinase 81312.m00088.AA AktR 324-586 39 2.4e-77 263.26 In-house 1-268 (268) Show / Hide 
Range on Protein: 324-586
Range on HMM: 1-268/268
Sequence Identity: 39% (108 aa)

FKFVKRISNGAFARVFLATKD-KLKSPVAIKVIPRRNVRGKGSTNRLLTEKNIML-HFNSPYTIRFFYSTIGKHNLYMVMEYLPGGDLFSLLEKFGCFPE
|.. | . .|||..|.|..|  . .  .|.|.|   . . .    ...||.|||  . | |  ....|.   | .|. .||| |||.||. | | . | |
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DVARNYTAQIVAALEYLRQN-NVIHRDLKPDNILLDSAGHLKLVDFGLSY-FGVVGRQTDTHESTALGTPDYIAPEIITL-ENHSYQADYWSLGAMLYEF
..|| | |||. ||||| |. |.| |||||.|||||. ||.|..|||||   ..  .  | .. . .||| |.|||.||  . | ...|.|..|. .|| 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFM--MHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEM

ITGVAPFHDNTPQEIFSNVLCGSINFKE---LEE-MNASKDCIDFIQ-KLLVSDPKKRLG--AESIDEIKHHPWF
.||  || ..  ...| .     |..|.    .. .. |. | |.|| |||  .|.||||  .....||| ||||
VTGCPPFYHKNQNQMFQK-----IKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 81312.m00088.AA CAMK 329-586 20 1e-76 246.57 In-house 1-425 (425) Show / Hide 
Range on Protein: 329-586
Range on HMM: 1-425/425
Sequence Identity: 20% (90 aa)

RISNGAFARVFLATKDKLK------------SPVAIKVIPRRNVRGKG-------------------------STNRLLTEKNIMLH-------FNSPYT
 .  |.|. |.|..  . .              ||||.|... ...|                          .  ... | .|| .        . |  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IRFFY--ST-----------IGKH-------NLYMVM---EYLPGG----DLFSLLEKFGC---------------FPEDVARNYTAQIVAALEYLRQNN
|...    .             ..       ..||||   || .||    |||. . . ||               |.|. || |  ||. |..|. ..|
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

VIHRDLKPDNILLDSA-----------------GHLKLVDFGLS--YFG---------VVGRQTDTHE-----------STALGTPDYIA-PEIIT----
..||||||.|||||.                  . .|..|||..  ...         . |..   |.           .|  ||| |.| ||..     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGH

----------LENHSYQADYWSLGAMLYEFITGVAPFHDN-------------TPQEIFSNVLCGSINFKELE---------------------EMNASK
           . .....| ||.| .||   .|  || .              ...|.| ... |  .| . .                     . . |.
CNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHH-FVSQ

DCIDFIQKLLVSDPKKRLGAESIDEIKHHPWF
.|.|.|.|.|. ||.||.   .|.... |||.
ECKDLIRKMLQVDPEKRM---TIEQCLNHPWM
Kinase 81312.m00088.AA RSK 351-586 36 2.2e-71 243.46 In-house 28-278 (278) Show / Hide 
Range on Protein: 351-586
Range on HMM: 28-278/278
Sequence Identity: 36% (92 aa)

AIKVIPRRNVRGKGS-TNRLLTEKNIMLHFN-SPYTIRFFYSTIGKHNLYMVMEYLPGGDLFSLLEKFGC---FPEDVARNYTAQIVAALEYLRQNNVIH
| ||. .. .. .   | . .|| ||... . .|  .. .|.   .  ||..|||..||.||  |.| ..   | || |. | |.|| |.|.| |  .||
AMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGCFSEDEACFYMAEIVLAVEHLHQQGIIH

RDLKPDNILLDS---AGHLKLVDFGLSYFGVVGRQTDTHESTALGTPDYIAPEIIT----LENHSYQADYWSLGAMLYEFITGVAPFHD---NTPQEIFS
|||||.|||.|.    ||.||.|||..  ..      |.  |  .| .|.|||...     . |. ..|.||||. .||  ||  ||.    |...||. 
RDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTM--TFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMK

NVLCGSINFKELEEMNASKDCIDFIQKLLVSDPKKRLG--AESIDEIKHHPWF
... | ....  .  . |... |.|.|.|  ||.||||   . ..||| ||||
RIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 81312.m00088.AA MAST 324-483 42 1.1e-63 193.22 In-house 1-163 (337) Show / Hide 
Range on Protein: 324-483
Range on HMM: 1-163/337
Sequence Identity: 42% (70 aa)

FKFVKRISNGAFARVFLATKDKLKSPVAIKVIPRRNVRGKGSTNRLLTEKNIMLHFNSPYTIRFFYSTIG--KHNLYMVMEYLPGGDLFSLLEKFG-CFP
|.|.| ||.||. .|.|. . | .  .|.|||  ..   |   . .  |.||      |..  .|||     |  |.|||||. ||| .|||. .| |.|
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EDVARNYTAQIVAALEYLRQNNVIHRDLKPDNILLDSAGHLKLVDFGLSYFGVVGRQTDTHES
|. |..|.|..| .||||     .||||||||.|.|| ||.||.||||| .| ....| . |.
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEG
Kinase 81312.m00088.AA MAST 324-484 42 3.1e-62 199.28 In-house 1-161 (334) Show / Hide 
Range on Protein: 324-484
Range on HMM: 1-161/334
Sequence Identity: 42% (68 aa)

FKFVKRISNGAFARVFLATKDKLKSPVAIKVIPRRNVRGKGSTNRLLTEKNIMLHFNSPYTIRFFYSTIGKHNLYMVMEYLPGGDLFSLLEKFGCFPEDV
|.|.| ||.||. .|.|. . | .  .|.|||  ..   |  .. . .|.||     .|..  .|||   | .|.|||||. |||..|||. .|.|.|. 
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARNYTAQIVAALEYLRQNNVIHRDLKPDNILLDSAGHLKLVDFGLSYFGVVGRQTDTHEST
|..|.|..| .|||| .   .||||||||.|.|| || ||.||||| .| . ... . |..
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGY
Kinase 81312.m00088.AA NDR 324-469 39 1.2e-50 154.12 In-house 1-151 (350) Show / Hide 
Range on Protein: 324-469
Range on HMM: 1-151/350
Sequence Identity: 39% (60 aa)

FKFVKRISNGAFARVFLATKDKLKSPVAIKVIPRRNVRGKGSTNRLLTEKNIMLHFN--SPYTIRFFYSTIGKHNLYMVMEYLPGGDLFS---LLEKFGC
|...| |. ||| .|.|. | . .  .|.|..    .  |  .. ...|. ||   .  .|.  . .|| . | .|| ||||.||||. .   || |...
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FPEDVARNYTAQIVAALEYLRQNNVIHRDLKPDNILLDSAGHLKLVDFGLS
|.||.|| | | .| |.|.. ... ||||.||||.|.|. ||.|| ||||.
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLC
Kinase 81312.m00088.AA MAST 486-586 44 4e-47 141.61 In-house 229-337 (337) Show / Hide 
Range on Protein: 486-586
Range on HMM: 229-337/337
Sequence Identity: 44% (49 aa)

LGTPDYIAPEIITLEN-HSYQADYWSLGAMLYEFITGVAPFHDNTPQE-IFSNVLC--GSINFKELEEMN----ASKDCIDFIQKLLVSDPKKRLGAESI
.|||||||||.|. .  ..  .|.||.| ..|||..|. || . ||.| ||.|..     |.. | .  |     |.. .| |.|||  .|||||||   
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA

DEIKHHPWF
|||| || |
DEIKQHPFF
Kinase 81312.m00088.AA NDR 487-586 37 8.3e-45 135.73 In-house 243-350 (350) Show / Hide 
Range on Protein: 487-586
Range on HMM: 243-350/350
Sequence Identity: 37% (40 aa)

GTPDYIAPEIITL-ENHSYQADYWSLGAMLYEFITGVAPFHDNTPQEIFSNVLCGSINF-----KELEEMNASKDCIDFIQKLLVSDPKKRLGAES--ID
|||||.|||...   ... . |.||||...||...|..||.. ||||.. ...   . .        .|.| |... | |..|.  ||..|||.    .|
GTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVD

EIKHHPWF
||| ||.|
EIKSHPFF
Kinase 81312.m00088.AA MAST 486-586 46 6.3e-43 136.0 In-house 225-334 (334) Show / Hide 
Range on Protein: 486-586
Range on HMM: 225-334/334
Sequence Identity: 46% (51 aa)

LGTPDYIAPEIITLEN-HSYQADYWSLGAMLYEFITGVAPFHDNTPQEIFSNVLCGS---INFKELEEMN----ASKDCIDFIQKLLVSDPKKRLGAE-S
.|||||||||.|. .  |.   |.||.| ..|||..|. || | ||.|||.|.|  .   | . | .  |     |.. .| |.|||  ||.|||||   
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

IDEIKHHPWF
 ||.| || |
ADEVKQHPFF
Kinase 81312.m00088.AA Pkinase_Tyr 324-469 28 9e-16 54.04 Pfam 1-158 (270) Show / Hide 
Range on Protein: 324-469
Range on HMM: 1-158/270
Sequence Identity: 28% (47 aa)

FKFVKRISNGAFARVFLATKD----KLKSPVAIKVIPRRNVRGKGSTNR------LLTEKNIMLHF-NSPYTIRFFYSTI-GKHN--LYMVMEYLPGGDL
 .| | .  ||| .|...| .    . | |||.|...       |.. .      .. | .|| .. . |  .|.    .  .    .|.|||| |.|||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE------GAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDL

FSLLEK----FGCFPEDVARNYTAQIVAALEYLRQNNVIHRDLKPDNILLDSAGHLKLVDFGLS
 . | |     . ..     .. .|| ...||| ..| |||||   |.|... .. |  ||||.
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 81312.m00088.AA TyrKc 324-586 23 1e-15 31.55 SMART 1-280 (280) Show / Hide 
Range on Protein: 324-586
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

FKFVKRISNGAFARVFLATKDKLKSPVAIKVIPRRNVRGKGSTNRLLTEKNIMLHF--NSPYTIRFFYSTIGK-------HNLYMVMEYLPGGDLFSLLE
 .. | . .||| .|...| .    .||.|..             .. | .|| ..  . |  .|..   . .       . |..|||| |.||| . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KFGC-FPEDVARNYTAQIVAALEYLRQNNVIHRDLKPDNILLDSAGHLKLVDFGLSYFGVVG-------RQTDTHE---STALGTPDYIAPEIITLENHS
| .  .. .   ..  || .  ||| ..|.|||||   |.|... .. |  ||||| ..  .          .. |   . ..      ||| |     .
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

YQADYWSLGAMLYEFIT-GVAPFHD-----NTPQEIFSNVLCGSINFKELE--EM---NASKDCIDFIQKLLVSDPKKRLGAESIDEIKHHPWF
 . | || | ...|  | |  |  .      ..||.. .|  |    .  .  .|    ....  . ...    ||..|   . |     |  |
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HECF
Kinase 81312.m00088.AA S_TK_X 587-650 25 4e-06 27.56 SMART 1-79 (79) Show / Hide 
Range on Protein: 587-650
Range on HMM: 1-79/79
Sequence Identity: 25% (20 aa)

NGIDWDNLD----KMEPPFIPDVK----DIFDTSNFEVKHILNMTDDSDIIE----DIRLGTDMLEI----AEGNFDSQF
 |||||.|     ..||||.|..|    . .|||||. .   .  ..... .     .     |..       ..|.  |
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNE-METEIPPDPFRGFTYVF
Kinase 81312.m00088.AA APH 443-472 23 0.000993 13.6 Pfam 172-205 (248) Show / Hide 
Range on Protein: 443-472
Range on HMM: 172-205/248
Sequence Identity: 23% (8 aa)

VIHRDLKPDNILLD--SAGHLK--LVDFGLSYFG
..|.|..|.|...|  . |     ..|.. . .|
WCHGDFHPGNVMWDPRPDGGRVTGVIDWDDACWG