Gene 100413.m00010 (T.vaginalis)

100413.m00010

Species: T.vaginalis
Alias: 100413.m00010, TvagK0357
External Links:
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
100413.m00010.AA Protein None 448 None Fasta, JSON
100413.m00010.kin_dom Protein Kinase Domain None 281 None Fasta, JSON

Protein domain

Protein domains of 100413.m00010.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 100413.m00010.AA AGC 96-376 28 3.5e-133 346.39 In-house 1-395 (395) Show / Hide 
Range on Protein: 96-376
Range on HMM: 1-395/395
Sequence Identity: 28% (117 aa)

FERIKLIGRGGFGEVWLVKDN------EDRNFYALKVLRKAD-IIMSE--QIQNVRTE------------RDILAHSD----------NPWFTY-LNCSF
|| .|.||.|.||.|.||...          .||.|||.|.. |.. .  ..... ||            |.||.. .          .|. .  | .||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDEER--LYLVLEYVC---------GG-DLMNALI---KKGVFDNDTAKFFIAE-------MTLAVHSVHE-LHFLHRD-LKPDNVLITESGHIKLTDFG
||...  ||.|.||..         || .|.  |    |.|.|| ..|.|..||       ..||... |. ... ||| |||.|.|..| |||||||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSK------------------NYQENDTRFQKLNDEIIELISGRPLDRPFHDR---------------GTEIG--TCSYTAPEILIGKPPTTLSDFWS--
|.|                  ..  | .  | .. .  .  . . . .  ...                |  |  |  | |||||     .   | ||  
LCKEGMNDGEKGQQSQSNMKFHW-HNKKY-Q-KS-NMDT-NK-CNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFG

LGVILYEMLYGFVPFMGQTSR----------ETALRII------AWKRCLVYP---QIEG-HPVSPLAVDLLQHLLC-DPEDRYG----------FEQII
||...||||.|  || |..            |.  .|.       ||  .  |   |...   .|| |.||...||| |||.| |          .|.| 
LGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIK

VHPFF
 ||.|
NHPWF
Kinase 100413.m00010.AA NDR 96-376 34 5.5e-124 384.49 In-house 1-350 (350) Show / Hide 
Range on Protein: 96-376
Range on HMM: 1-350/350
Sequence Identity: 34% (122 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSD--NPWFTYLNCSFQDEERLYLVLEYVCGGDLMN---ALIKKGV
|| ||.||.|.|||||||. .. ...||.|..||..... .|. .||.||||.| .|  |||.. | .||||.  |||| ||..|||.|     |.|...
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FDNDTAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFGLSKN----------------------YQENDTRFQKLNDEIIELISGRPLD
|. | |.| ||||..|..|||.. . |||.|||| ||   ||||||||||...                       ......... ..|. .  . .. .
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

RPFHDRGT--------------------------------EIGTCSYTAPEILIG-KPPTTLSDFWSLGVILYEMLYGFVPFMGQTSRETALRIIAWKRC
. . ....                                 .||  |.|||.. . .  . . |.||||.|.|||| |. || . | .||  .|. || .
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

LVYP--QIE-GHPVSPLAVDLLQHLLC-DPEDRYG-----FEQIIVHPFF
.  |  ...   ..|| |.||.. |.| ||. | |     ...|  ||||
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase 100413.m00010.AA DMPK 96-239 44 1.2e-84 208.82 In-house 1-145 (270) Show / Hide 
Range on Protein: 96-239
Range on HMM: 1-145/270
Sequence Identity: 44% (64 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSDNPWFTYLNCSFQDEERLYLVLEYVCGGDLMNALIKKG-VFDND
|| .|.|||| |||| .|.  . .  || |.. |.. .  ..   .. ||||..|.. .| | | . ||||. ||.| || .|||| . . . . ... |
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

TAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFG
 |.| .|||.||.||.|.... ||| ||||.|.  .||||| |||
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFG
Kinase 100413.m00010.AA S_TKc 96-376 28 3e-84 287.1 SMART 1-231 (231) Show / Hide 
Range on Protein: 96-376
Range on HMM: 1-231/231
Sequence Identity: 28% (84 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSDNPWFTYLNCSFQDEERLYLVLEYVCG--GDLMNALIKKGV---
.| ...||.|.||.|........   .|.|...          ...| |..|| . . |.   |  .||| ..||.|.||. |  |||.  . |.|    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDNDTAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFGLSKNYQENDTRFQKLNDEIIELISGRPLDRPFHDRGTEIGTCSYTAPE
   |.  .|.|..... .|.   |.....||||||.|.|..|  |||..||||.. .                               | .||  | |||
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------TTFCGTPWYMAPE

ILIGKPPTT-LSDFWSLGVILYEMLYGFVPFMGQTSRETALRIIAWKRCLVYPQIEGHPVSPLAVDLLQHLLC-DPEDRYGFEQIIV-------HPFF
.|   . ..  .| ||.|.||||||.|  ||      .. ...|                || | |.....|. |||.|..  ..         ||.|
VL---GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG---------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 100413.m00010.AA RSK 99-376 34 6.7e-71 241.85 In-house 1-278 (278) Show / Hide 
Range on Protein: 99-376
Range on HMM: 1-278/278
Sequence Identity: 34% (104 aa)

IKLIGRGGFGEVWLVKDN---EDRNFYALKVLRKADIIMSEQ-IQNVRTERDILAHSD-NPWFTYLNCSFQDEERLYLVLEYVCGGDLMNALIKKGV---
.|. |.||.|.| |..       .  || |||.|| |. ..  .  ..|||.||...   |    |. .||.|. |||..||. ||.|   | |..    
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDNDTAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITE---SGHIKLTDFGLSKN-YQENDTRFQKLNDEIIELISGRPLDRPFHDRGTEIGTCSYTAP
|. |.|.| .|| .|||   |.... ||||||.|.| ..   .|||||||||..|    ..  . ..                        ..|  | ||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMT-----------------------FCYTIEYMAP

EILI---GKP-PTTLSDFWSLGVILYEMLYGFVPFMG---QTSRETALRIIAWKRCLVYP--QIEGHPVSPLAVDLLQHLLC-DPEDRYG-----FEQII
|.|    ..   .   | |||||..|||| |..|| |   ... |.  ||   |  |  |  |     .|. | ||....|. ||..|.|      |.| 
EMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQY----LSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIK

VHPFF
 ||.|
QHPWF
Kinase 100413.m00010.AA Ciliate-E2 96-376 24 4.3e-67 229.2 In-house 1-365 (365) Show / Hide 
Range on Protein: 96-376
Range on HMM: 1-365/365
Sequence Identity: 24% (93 aa)

FERIKLIGRGGFGEVWLVKDNEDRN-----------------------FYALKVLRKADIIMSEQIQNVR----------TERDILAHSDNPWFTYLNCS
.. ||.||.|.|| |...|. ....                       .||.|...| .|.. .|....            |. || . ..|    .  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--DEERLYLVLEYVCGGDLMNALIKK-----------GVFDNDTAKFFIAEMTL---------------AVHSVHELH-FLHRDLKPDNVLITESGHI
||  |.. .|||.||. ||||.  ....           . |.   .|..... .                |... |. .  .|||.||.|.|.     |
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLTDFGLSKNYQENDTRFQKLNDEIIELISGR-PLDRPFHDRGTEI-----------GTCSYTAPEILIGKP---------PTTLSDFWSLGVILYEMLY
|..||||||.|...  . .. . .  ...  .   .| . . .  .           ||  | ||||| ||.          .. .|.|||||||||||.
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMD--QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLF

GFVPFMGQTSRETALRIIAWKRCLVYPQIE---------------GHPVSPLAVDLLQH-----LLCDPEDRYG-FEQIIVHPFF
|  ||           ..  | | .  . .                . .|. . ||..      | .||| |.. .|||. ||.|
GKPPF-----------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase 100413.m00010.AA MAST 96-242 46 3.6e-64 205.62 In-house 1-147 (334) Show / Hide 
Range on Protein: 96-242
Range on HMM: 1-147/334
Sequence Identity: 46% (68 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSDNPWFTYLNCSFQDEERLYLVLEYVCGGDLMNALIKKGVFDNDT
|| ||.|..|..| |.||| .. . ..|.||..|.| |   ....|..||.||| ..||.   . .||| .. |..|.||. |||.   |   | || ..
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

AKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFGLSK
||. |||. |..   |.    ||||||||.||. .||||||||||||
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase 100413.m00010.AA MAST 96-242 43 2.6e-63 191.99 In-house 1-150 (337) Show / Hide 
Range on Protein: 96-242
Range on HMM: 1-150/337
Sequence Identity: 43% (65 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSDNPWFTYLNCSFQD--EERLYLVLEYVCGGDLMNALIKKG-VFD
|| ||.|..|..| |.|||  . . ..|.||... |.|   |...|. ||.||.  .||.   . .|||   .. |..|.||. |||    |   |  ..
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

NDTAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFGLSK
 . ||. |||  |..   |.    ||||||||.||.  ||||||||||||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSK
Kinase 100413.m00010.AA Pkinase 96-376 26 3.9e-63 220.86 Pfam 1-293 (293) Show / Hide 
Range on Protein: 96-376
Range on HMM: 1-293/293
Sequence Identity: 26% (84 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVR-TERDILAHSDNPWFTYLNCSFQDEERLYLVLEYVCGG----DLMNALI--KK
..... ||.|.||.|.. ..  ..  .|.|...| .. ........| .|  |... . |    | ..|.|. ..|.|.||. ||    ||.  .   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

GVF--DNDTAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHI----KLTDFGLSKNYQENDTRFQKLNDEIIELISGRPLDRPFHDRGTEIGTCS
|.|  . ...||.. ..  ..   |.  ..||||||.|.|| . |||    |..||||.| ..                        . .   |  ||  
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD----------------------Y-NNS-MTTFCGTPW

YTAPEILI-GKPPTTLSDFWSLGVILYEMLYGFVPFMGQ---TSRETALRIIAWKRC--LVYPQIEGHPVS-----------------PLAVDLLQHLLC
| |||..  |.. .. .| ||.|.|||||| |  || |.    .  . . .|. ...  | ..  . ...|                 . . |..  .||
YMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLC

-DPEDRYGFEQIIVHPFF
 ||..|...|||  ||.|
KDPKKRPTAEQILQHPWF
Kinase 100413.m00010.AA AktR 96-248 37 3.5e-54 186.33 In-house 1-158 (268) Show / Hide 
Range on Protein: 96-248
Range on HMM: 1-158/268
Sequence Identity: 37% (60 aa)

FERIKLIGRGGFGEVWLVKDN-EDRNFYALKVLRKADIIMSEQIQNVRTERDILA-HSDNPWFTYLNCSFQDEERLYLVLEYVCGGDLMNALIKKGVFDN
|...|..|.|.||.| ||... ..  .||.|...| .||  .|.. ..|||.|.. ....| .  |  .||..| |....||..||.| . | ||. |..
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

DTAKFFIAEMTLAVHSVHEL-HFLHRDLKPDNVLITESGHIKLTDFGLSK--NYQEND
..|.|..|.. ||.   |.  .   |||||.| |. | ||.|.|||||||  .  ..|
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYD
Kinase 100413.m00010.AA CRIK 96-239 44 7.5e-54 169.88 In-house 1-145 (272) Show / Hide 
Range on Protein: 96-239
Range on HMM: 1-145/272
Sequence Identity: 44% (64 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSDNPWFTYLNCSFQDEERLYLVLEYVCGGDLMNALIKKG-VFDND
||   |||.| ||.| .|        || ||..|. .  .||.  .  ||||.. .  || . |   |||.. |||. ||  ||||   .   . .|| .
FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN

TAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFG
 |.|. || ..||||.||  . ||| ||.|.||   ||||| |||
MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFG
Kinase 100413.m00010.AA GEK 96-239 48 9.8e-53 175.16 In-house 1-145 (269) Show / Hide 
Range on Protein: 96-239
Range on HMM: 1-145/269
Sequence Identity: 48% (71 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHSDNPWFTYLNCSFQDEERLYLVLEYVCGGDLMNALIK-KGVFDND
|| .|.|||| ||||  ||  .  . ||.|.| | ...    .   | |||.| . |. | | |   ||||. ||||..| .||||.  | | .    .|
FEILKVIGRGAFGEVAVVKMKNTDQVYAMKILNKWEMLKRAETACFREERDVLVNGDRRWITNLHYAFQDENYLYLVMDYYVGGDLLTLLSKFEDRLPED

TAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFG
 |.|.|||| .|..|||.||. |||.||||||. . |||.| |||
MARFYIAEMVMAIDSVHQLHYVHRDIKPDNVLLDMNGHIRLADFG
Kinase 100413.m00010.AA DMPK 299-376 43 1e-33 80.03 In-house 189-270 (270) Show / Hide 
Range on Protein: 299-376
Range on HMM: 189-270/270
Sequence Identity: 43% (36 aa)

DFWSLGVILYEMLYGFVPFMGQTSRETALRIIAW-KRCLVYPQIEGHPVSPLAVDLLQHLLCDPEDRYG---FEQIIVHPFF
|.||.||..||||||  ||   .. ||   |    |..|  |. . . ||. | ||.. ||||.|.| |   .|..  ||||
DWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRNGYEDFKCHPFF
Kinase 100413.m00010.AA CRIK 299-376 38 1.8e-24 74.63 In-house 191-272 (272) Show / Hide 
Range on Protein: 299-376
Range on HMM: 191-272/272
Sequence Identity: 38% (32 aa)

DFWSLGVILYEMLYGFVPFMGQTSRETALRIIA------WKRCLVYPQIEGHPVSPLAVDLLQHLLCDPEDRYGFEQIIVHPFF
|.||.|.| ||| .|  ||   .. .|   |.        .| | .|     .||| . ||.| |||..  | ..||.  ||||
DWWSMGIIAYEMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFP--DDPKVSPNYRDLIQSLLCNQSKRLKYEQLCCHPFF
Kinase 100413.m00010.AA MAST 278-376 36 4.3e-21 60.61 In-house 229-337 (337) Show / Hide 
Range on Protein: 278-376
Range on HMM: 229-337/337
Sequence Identity: 36% (40 aa)

IGTCSYTAPEILIGKP-PTTLSDFWSLGVILYEMLYGFVPFMGQTSRE-TALRIIAWKRCLVYPQI----EGHPVSPLAVDLLQHLL-CDPEDRYGFE--
.||  | |||.. |..      | ||.|.|.|| | | .|| | |  | .   ||  .| . .| .    .. ..|| | || . ||  .| .| |.   
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA

-QIIVHPFF
 .|  ||||
DEIKQHPFF
Kinase 100413.m00010.AA GEK 299-376 41 4.5e-19 60.28 In-house 188-269 (269) Show / Hide 
Range on Protein: 299-376
Range on HMM: 188-269/269
Sequence Identity: 41% (34 aa)

DFWSLGVILYEMLYGFVPFMGQTSRETALRIIAWKRCLVYPQIEG-HPVSPLAVDLLQHLLCDPEDRY---GFEQIIVHPFF
|.|||||..||||||  ||  .   ||  .|. .| .. .|. |  . ||  | ||...|.| .| |    | .    ||||
DWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHKDHFQFPSQETDWDVSEEAKDLIRQLICSQEHRLGRNGIQDFKKHPFF
Kinase 100413.m00010.AA MAST 278-376 33 6e-19 57.41 In-house 225-334 (334) Show / Hide 
Range on Protein: 278-376
Range on HMM: 225-334/334
Sequence Identity: 33% (37 aa)

IGTCSYTAPEILIGKP-PTTLSDFWSLGVILYEMLYGFVPFMGQTSRETALRIIAWKRC-LVYPQI----EGHPVSPLAVDLLQHLL-CDPEDRYGFE--
.||  | |||.. |..     .| ||.|.|.|| | | .|| . |  |.   |.  ..    .|      ..   || | || . || .||..| |.   
CGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMSPEAQDLIEKLLQPDPRKRLGANNG

--QIIVHPFF
  ..  ||||
ADEVKQHPFF
Kinase 100413.m00010.AA AktR 279-376 31 1.5e-13 48.78 In-house 166-268 (268) Show / Hide 
Range on Protein: 279-376
Range on HMM: 166-268/268
Sequence Identity: 31% (33 aa)

GTCSYTAPEILIG-KPPTTLSDFWSLGVILYEMLYGFVPFMGQTSRETALRIIAWKRCLVYPQIEGHPVSPLAVDLLQ-HLLC-DPEDRYG-----FEQI
||  | |||..   |. .  .|.|..|. .|||..|  ||  . .... .  |  |.  .....   ..|. . ||.|  ||| .|. | |     .|.|
GTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHK-NQNQMFQKIKIKQ-QNKFPYP-SYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEI

IVHPFF
  ||.|
KSHPWF
Kinase 100413.m00010.AA TyrKc 96-376 23 1.3e-12 -18.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 96-376
Range on HMM: 1-280/280
Sequence Identity: 23% (71 aa)

FERIKLIGRGGFGEVWLVKDNEDRNFYALKVLRKADIIMSEQIQNVRTERDILAHS--DNPW-FTYLNCSFQDE------ERLYLVLEYVCGGDLMNALI
 . .| .|.| ||||.. . .      | |.|..        ..  . |  |. .   ..|     . .  |..      | |..|.||...||| . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KKGV-FDNDTAKFFIAEMTLAVHSVHELHFLHRDLKPDNVLITESGHIKLTDFGLSKNYQENDTRFQKLNDEIIELISGRPLD--RPFHDRGTEIGTCSY
|..  . ...   |           |. .. ||||   |.|..| ...| .|||||..  . |..    ... .   ...  .   |             
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--ESKDYYRKKEHKGGKTMLPIR----------W

TAPEILIGKPPTTLSDFWSLGVILYEML-YGFVPFMG-----QTSRETALRIIAWKRCLVYPQIEGHPVSPL----AVDLLQHLLC-----DPEDRYGFE
.||| .  .  || || || || ..|.. ||  |  |      . .|   .. . .|    | ..     |.    . | .  .       |||||  |.
MAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY-----PMSFVCCPDEMYQIMKQCWHEDPEDRPTFS

QIIVHPFF
.|  | .|
EI--HECF
Kinase 100413.m00010.AA Pkinase_C 394-432 38 3e-06 25.15 Pfam 1-41 (46) Show / Hide 
Range on Protein: 394-432
Range on HMM: 1-41/46
Sequence Identity: 38% (16 aa)

VIKSPTDTSHFDEIEPSEQPLAAS---IPLANISQFAFLGFT
 .|||||||.||. . .| |   .     . .. | .| |||
QVKSPTDTSNFDPEFTDEPPMDTPPDWR-MSSGDQEPFRGFT
Kinase 100413.m00010.AA Pkinase_Tyr 211-249 35 5e-06 20.98 Pfam 128-166 (270) Show / Hide 
Range on Protein: 211-249
Range on HMM: 128-166/270
Sequence Identity: 35% (14 aa)

HELHFLHRDLKPDNVLITESGHIKLTDFGLSKNYQENDT
.. .. ||||   |.|.||....| .||||..  .. |.
ESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDY
Kinase 100413.m00010.AA S_TK_X 377-435 31 2.6e-05 22.34 SMART 1-79 (79) Show / Hide 
Range on Protein: 377-435
Range on HMM: 1-79/79
Sequence Identity: 31% (25 aa)

QGFDFDNPFS----NSPPMVPVIK----SPTDTSHFDEIEPSEQPLAASI--PLANISQFA----------FLGFTIKP
 |.|.|. ..      || .| ||    |||||| ||. ...|.| .  .  || |...            |.||| . 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPMLTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 100413.m00010.AA Pkinase_Tyr 96-112 41 0.158838 5.79 Pfam 1-17 (270) Show / Hide 
Range on Protein: 96-112
Range on HMM: 1-17/270
Sequence Identity: 41% (7 aa)

FERIKLIGRGGFGEVWL
 . .| .|.| ||||..
ITFGKKLGEGAFGEVYK
Kinase 100413.m00010.AA Pkinase_Tyr 165-181 42 0.235618 5.21 Pfam 76-94 (270) Show / Hide 
Range on Protein: 165-181
Range on HMM: 76-94/270
Sequence Identity: 42% (8 aa)

DEER--LYLVLEYVCGGDL
..|   .|.|.||...|||
QGEPNQIYIVMEYMPHGDL
Kinase 100413.m00010.AA Pkinase_Tyr 295-329 37 1.023224 3.05 Pfam 192-228 (270) Show / Hide 
Range on Protein: 295-329
Range on HMM: 192-228/270
Sequence Identity: 37% (14 aa)

TTLSDFWSLGVILYEMLY-GFVP-FMGQTSRETALRI
|| || || || ..|..  |  | . | .  |   .|
TTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYI
Kinase 100413.m00010.AA Pkinase_C 376-385 50 23.726804 1.1 Pfam 37-46 (46) Show / Hide 
Range on Protein: 376-385
Range on HMM: 37-46/46
Sequence Identity: 50% (5 aa)

FQGFDFDNPF
|.|| . ||.
FRGFTYVNPD