Gene 96581.m00100 (T.vaginalis)

96581.m00100

Species: T.vaginalis
Alias: TvagK0439, 96581.m00100
External Links:
Annotation:

Classification

Group: AGC
Family: MAST
Subfamily: MAST

Sequence

Name Sequence Type Origin Length Description Download
96581.m00100.AA Protein None 768 None Fasta, JSON
96581.m00100.kin_dom Protein Kinase Domain None 271 None Fasta, JSON

Protein domain

Protein domains of 96581.m00100.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96581.m00100.AA AGC 318-588 29 2.8e-138 359.9 In-house 1-395 (395) Show / Hide 
Range on Protein: 318-588
Range on HMM: 1-395/395
Sequence Identity: 29% (117 aa)

FELIERISSGAYARVYLAKKK------LTGDIFAIKVLPKSG-LVQKN--QLKRILLE------------KDILLQFN----------NPYVTN-FYYSI
||..  |. |.. .|||..||       ||...|.||| |.   |.|.  ...... |            ..|| . |          .|....  .|| 
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

IGTRN--LYLVMEY---------IGGG-DLFSLLE---KFGCFDEGSARIYTYQ-------IVRALQYLYQ-NGIIHRD-LKPDNILVTSEGYLKLADFG
   ..  ||.||||         .||| .||. |    | |.|||  ||.|. .       || ||.|| . .|||||| |||.||| ...|..||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSHLGMKNRERPNDTID-------------------------------------FRVKENVIQSHSLVG--TPDYISPEIILGQPHSFTTDYWS--LGVI
|.  ||...| .   ..                                         ..  . ....|  ||.|..|||.    .... |.||  ||..
LCKEGMNDGEKGQQ-SQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTR-KKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCL

VYEMLTGAMPFHTES----------EQHTFKNIVKGI---YAPLTD-------------VSPDAADFVKRLLYSDPRKRLGCH-------GPDEILNHPW
 ||||||  ||. ..          .  .|..| .|.     ...              .||.| |..|.||  ||.|||||.       | .|| ||||
MYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPW

L
 
F
Kinase 96581.m00100.AA MAST 318-588 35 1.2e-113 348.7 In-house 1-337 (337) Show / Hide 
Range on Protein: 318-588
Range on HMM: 1-337/337
Sequence Identity: 35% (118 aa)

FELIERISSGAYARVYLAKKKLTGDIFAIKVLPKSGLVQKNQLKRILLEKDILLQFNNPYVTNFYYSIIG--TRNLYLVMEYIGGGDLFSLLEKFG-CFD
|| |. || ||| .|||.|.| |.|.||.||. ....  |||.. .  |..|| .  ||.| ...||     .. |..||||  ||| .|||. .| |..
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EGSARIYTYQIVRALQYLYQNGIIHRDLKPDNILVTSEGYLKLADFGLSHLGMKN---RERPN------------DTIDFRVKENVIQ------------
|  |..|. ..| .| ||   ||.||||||||.| .| | .||.|||||  | ..   .. .             . ...  . .  |            
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN

------------------------SHSLVGTPDYISPEIILGQP-HSFTTDYWSLGVIVYEMLTGAMPFHTESEQH-TFKNIVK---GIYAPLT------
                          . .||||||.||.||||. .. . |.||.|.|.|| |.|  ||  .. .  .| ||..    |. | .      
QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD

-DVSPDAADFVKRLLYSDPRKRLGCHGPDEILNHPWL
  .||.| | .|.||  .|.||||  | ||| .||  
DCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF
Kinase 96581.m00100.AA MAST 318-588 36 1.1e-109 354.8 In-house 1-334 (334) Show / Hide 
Range on Protein: 318-588
Range on HMM: 1-334/334
Sequence Identity: 36% (122 aa)

FELIERISSGAYARVYLAKKKLTGDIFAIKVLPKSGLVQKNQLKRILLEKDILLQFNNPYVTNFYYSIIGTRNLYLVMEYIGGGDLFSLLEKFGCFDEGS
|| |. || ||| .|||.|.| |.|.||.||. ||..  ||...    |..|| .  ||.| ...||   ...|..||||  |||..|||. .|.|||  
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

ARIYTYQIVRALQYLYQNGIIHRDLKPDNILVTSEGYLKLADFGLSHLGMKN-----RER------------PNDTIDFRVKE-----------------
|..|. ..| .|.|| . ||.||||||||.| .|.|  ||.|||||  |...      |             | ....   ..                 
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNIFNNSTDPMNKNQQDYSQFPGDFGINGNTNKNQIQ

----------------NVIQSHSLVGTPDYISPEIILGQP-HSFTTDYWSLGVIVYEMLTGAMPFHTESEQHTFKNIVKGI-----YAPL------TDVS
                |. |  ...||||||.||.||||. |. . |.||.|.|.|| |.| .||  .. . .| ||..       . .          |
QQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGGDINDDEAMS

PDAADFVKRLLYSDPRKRLGCH-GPDEILNHPWL
|.| | ...||  |||||||   | ||. .|| .
PEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase 96581.m00100.AA S_TKc 318-588 33 6.3e-100 339.2 SMART 1-231 (231) Show / Hide 
Range on Protein: 318-588
Range on HMM: 1-231/231
Sequence Identity: 33% (96 aa)

FELIERISSGAYARVYLAKKKLTGDIFAIKVLPKSGLVQKNQLKRILLEKDILLQFNNPYVTNFYYSIIGTRNLYLVMEYIGG--GDLFSLLEKFGC---
.|... | .||...||....| || |.|||...          ..|. | .|| . . |.. ..|...    .||.||||..|  ||||....| |.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDEGSARIYTYQIVRALQYLYQNGIIHRDLKPDNILVTSEGYLKLADFGLSHLGMKNRERPNDTIDFRVKENVIQSHSLVGTPDYISPEIILGQPHS
   |.|  || |.|||..||.|. ..|||||||||.|||...   .|..||||. .                       ....|||.|..||..   ...
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------------------TTFCGTPWYMAPEVL---GYG

F-TTDYWSLGVIVYEMLTGAMPFHTESEQHTFKNIVKGIYAPLTDVSPDAADFVKRLLYSDPRKRLGCHGPDE----ILNHPWL
.   | ||.|.|.||||.|  ||.   .| .||.|.          ||.| ||....|  ||.||...    .    | .|||.
KCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 96581.m00100.AA AktR 318-588 33 1.8e-87 296.94 In-house 1-268 (268) Show / Hide 
Range on Protein: 318-588
Range on HMM: 1-268/268
Sequence Identity: 33% (95 aa)

FELIERISSGAYARVYLAKKK-LTGDIFAIKVLPKSGLVQKNQLKRILLEKDILL-QFNNPYVTNFYYSIIGTRNLYLVMEYIGGGDLFSLLEKFGCFDE
|.... . .||...|||..||  .....|.|.. |. ....|| .....|..|.  . |.|   ...|..   ..|...|||. ||.||. | | . |.|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

GSARIYTYQIVRALQYLYQN-GIIHRDLKPDNILVTSEGYLKLADFGLSHLGMKNRERPNDTIDFRVKENVIQS----HSLVGTPDYISPEIILG-QPHS
  ||.|  ||. ||.|| |.  || |||||.|||  ..|..|..|||||                   ....      .|..||| |..||.|.  ..| 
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-----------------LQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHN

FTTDYWSLGVIVYEMLTGAMPFHTESEQHTFKNIVKGI--YAPL-TDVSPDAADFVK-RLLYSDPRKRLG--CHGPDEILNHPWL
.. |.|..|. .|||.||  ||  .. .  |..| .    . |  ...|. . |... .||  .|.||||  | |..|| .||| 
KSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 96581.m00100.AA Ciliate-E2 318-588 25 2.2e-85 289.96 In-house 1-365 (365) Show / Hide 
Range on Protein: 318-588
Range on HMM: 1-365/365
Sequence Identity: 25% (97 aa)

FELIERISSGAYARVYLAKKKLTGD-----------------------IFAIKVLPKSGLVQKNQLKRIL----------LEKDILLQFNNPYVTNFYYS
...|. | .|... ||..|.....                        |.|.|.. |... |..| ..|.           || || | |.|.. ..|..
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

II--GTRNLYLVMEYIGGGDLFSLLEKF-----------GCFDEGSARIYTYQIVR---------------ALQYLYQNG-IIHRDLKPDNILVTSEGYL
 .   . |.||||||. |||||......           ..|.|  .. ...||..               ||.|| ... |||||.||.|||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KLADFGLS-HLGMKNRER-----PNDTIDFRVKENVIQS-----------HSLVGTPDYISPEIILGQP---------HSFTTDYWSLGVIVYEMLTGAM
|..|||||  .  .| .|      .  .. ...... ..           ....||| | .|||. |..         ...  |.|||||| ||||.|  
KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP

PFHTESEQHTFKNIVKGIYA------------------PLTDVSPDAADFVKR----LLYSDPRKRLGCHGPDEILNHPWL
||        ...| .. .                      ..|... |. |.    .|  || ||..  |...||||||.
PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 96581.m00100.AA Pkinase 318-588 29 3.3e-84 290.88 Pfam 1-293 (293) Show / Hide 
Range on Protein: 318-588
Range on HMM: 1-293/293
Sequence Identity: 29% (92 aa)

FELIERISSGAYARVYLAKKKLTGDIFAIKVLPKSGLVQKNQLKRILL--EKDILLQFNNPYVTNFYYSIIGTRNLYLVMEYIGGG----DLFSLLE--K
......| ||....||....| ||.|.|.|...|.    ...... ..  |  |.. .| |..  .|..    ...|.|||| .||    |||....  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

FGCF--DEGSARIYTYQIVRALQYLYQNGIIHRDLKPDNILVTSEGYL----KLADFGLSHLGMKNRERPNDTIDFRVKENVIQSHSLVGTPDYISPEII
 |||  .|  .. | |||.|.|.|....|||||||||.|||. ..|..    |..||||. .                  |.   ....|||.|..||.|
HGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-------------Y-NNS--MTTFCGTPWYMAPEVI

L-GQPHSFTTDYWSLGVIVYEMLTGAMPFHTE------SEQHTFKNIVKGIYAPLTDVS---------------------PDAADFVKRLLYSDPRKRLG
. ||...   | ||.|.|.||||.|  ||  .      .... ...| ....    . .                     ... ||.|..|  || ||..
RGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT

CHGPDEILNHPWL
   ...||.|||.
---AEQILQHPWF
Kinase 96581.m00100.AA CAMK 323-588 20 3.6e-83 267.71 In-house 1-425 (425) Show / Hide 
Range on Protein: 323-588
Range on HMM: 1-425/425
Sequence Identity: 20% (92 aa)

RISSGAYARVYLAKKKLTG------------DIFAIKVLPKSGLVQKN-------------------------QLKRILLEKDILLQ-------FNNPYV
 . .|... |.|.. |.|.              .|||...|. |  |.                          .|... | .|. .        . | .
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

TNFYYSIIG-------------------TRNLYLVM---EYIGGG----DLFSLLEKFGC---------------FDEGSARIYTYQIVRALQYLYQNGI
 ..|  .                     ....|.||   ||. ||    |||. . . ||               |.|  || |  ||. |..|. ...|
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDLKPDNILVTSEG----------------Y-LKLADFGLS--HLG---------MKNRERPNDTIDFRVKENVIQ---------SHSLVGTPDYIS-
.||||||.|||... .                . .|..|||..    .         .|..|   ..          |          .  .||| |.. 
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN----------QWTTPTEGQKMKTFCGTPEYMAA

PEIILG--------------QPHSFTTDYWSLGVIVYEMLTGAMPFHTE-------------SEQHTFKNIVKGIYA-PLTD------------------
||...|              ..... .| ||.||| | ||.| .||  .             ... .|..| || |  |                     
PEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISD

-----VSPDAADFVKRLLYSDPRKRLGCHGPDEILNHPWL
     ||... |.....|  || ||. ..   ..|||||.
EFHHFVSQECKDLIRKMLQVDPEKRMTIE---QCLNHPWM
Kinase 96581.m00100.AA RSK 321-588 34 2.1e-77 263.46 In-house 1-278 (278) Show / Hide 
Range on Protein: 321-588
Range on HMM: 1-278/278
Sequence Identity: 34% (100 aa)

IERISSGAYARVYLAKKK---LTGDIFAIKVLPKSGLVQKNQ-LKRILLEKDILLQFN-NPYVTNFYYSIIGTRNLYLVMEYIGGGDLFSLLEKFGC---
..    |.|  |.| .|.    || |.| ||| |. .||..  ... . | .||.  .  | . . .|.      |||.|||. ||.||  |.| ..   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDEGSARIYTYQIVRALQYLYQNGIIHRDLKPDNILVTS---EGYLKLADFGLSHLGMKNRERPNDTIDFRVKENVIQSHSLVGTPDYISPEIIL---GQ
|.|  |..| ..|| |...| | |||||||||.||| ..   || .|| |||.. ..              . ..  . .. ..| .|. ||..    .|
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF--------------RCDHNQWTMTFCYTIEYMAPEMLKRANQQ

P-HSFTTDYWSLGVIVYEMLTGAMPFHT---ESEQHTFKNIVKGI--YAPL--TDVSPDAADFVKRLLYSDPRKRLGC--HGPDEILNHPWL
  |.   |.|||||. ||||||. ||.    .. . ..|.| ||           .|..| |.....|  || |||||   . .||..|||.
GGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 96581.m00100.AA Ciliate-E2-Unclassified 318-588 27 2.6e-77 263.15 In-house 1-352 (352) Show / Hide 
Range on Protein: 318-588
Range on HMM: 1-352/352
Sequence Identity: 27% (97 aa)

FELIERISSGAYARVYLAKKKLTGDIFAIKVLPKSGLVQKNQLKR---------ILLEKD-------------ILLQFNNPYVTNFYYSIIGTRNLYLVM
...|. | .|... ||....| .. ..|.| . |.  . ..| ..         .. .|              |||....|.. ...|    . |.|.||
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYIGGGDLFSLLEKF-----------------GCFDEGSAR-----IYTYQIVRALQYLYQNG-IIHRDLKPDNILVTSEG---YLKLADFGLS-HLGMK
||. ||||.  ..|.                  .|.|  |.      |..||. .|.|| ... |||||.||.|||....|   |.|..|||.| ...  
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

NRERPNDTIDFRVKENVIQSHSL---VGTPDYI----SPEIILGQPHS----FTTDYWSLGVIVYEMLTGAMPF-HTESEQH---------------TFK
| .. ..     .| ...... .   .||| |.    .||.. || ..    .  |.|||||| ||||.|  ||  . .|||                ..
NNCD-TNQQ---QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQ

NIVKGIYAPLT--------DVSPDAADFVK----RLLYSDPRKRLGCHGPDEILNHPWL
|| ....            ..|| |.||..    ..|  .| ||.   ....||||||.
NIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRI---TFEQILNHPWF
Kinase 96581.m00100.AA NDR 318-470 43 9.3e-63 192.13 In-house 1-158 (350) Show / Hide 
Range on Protein: 318-470
Range on HMM: 1-158/350
Sequence Identity: 43% (69 aa)

FELIERISSGAYARVYLAKKKLTGDIFAIKVLPKSGLVQKNQLKRILLEKDILLQFN--NPYVTNFYYSIIGTRNLYLVMEYIGGGDLFS---LLEKFGC
|| |. |..||. .|.|..|| ||.|.|.|.. ||  ..|||.. .. |.||. . .  ||.|.  ||| .   .|||||||. |||. .   || |...
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

FDEGSARIYTYQIVRALQYLYQNGIIHRDLKPDNILVTSEGYLKLADFGLSHLGMKNR
|.|  || |   .| |. .. ..|.||||.||||.|. . | .|| ||||.  ||  |
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRR
Kinase 96581.m00100.AA Akt 318-472 37 3e-58 184.75 In-house 1-158 (264) Show / Hide 
Range on Protein: 318-472
Range on HMM: 1-158/264
Sequence Identity: 37% (60 aa)

FELIERISSGAYARVYLAKKKLTGDIF-AIKVLPKSGLVQKNQLKRILLEKDILLQFNNPYVTNFYYSIIGTRNLYLVMEYIGGGDLFSLLEKFGCFDEG
|.... . .|....|.|.||| |.... |.||| |. ..||||.. .. |. ||   |.|...| .||     .||.||.|..||.||..| . . |.| 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

SARIYTYQIVRALQYLYQNGIIHRD-LKPDNILVTSEGYLKLADFGLSHLG-MKNRER
 || |  .|. |...| ...|| || ||| |||. ..|...|.||||.  . .|. ..
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDK
Kinase 96581.m00100.AA NDR 489-588 40 1.1e-36 110.18 In-house 239-350 (350) Show / Hide 
Range on Protein: 489-588
Range on HMM: 239-350/350
Sequence Identity: 40% (45 aa)

HSLVGTPDYISPEIILG-QPHSFTTDYWSLGVIVYEMLTGAMPFHTESEQHTFKNIVKG---------IYAPLTDVSPDAADFVKRLLYSDPRKRLGCHG
.|.||||||. ||.... . ...| |.||||.| ||||.|  ||. .. | |...| .           . |   .||.|.|  .||.  || .||| ||
YSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQTWDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHG

--PDEILNHPWL
   ||| .||. 
KGVDEIKSHPFF
Kinase 96581.m00100.AA Akt 482-588 36 2.8e-35 110.19 In-house 149-264 (264) Show / Hide 
Range on Protein: 482-588
Range on HMM: 149-264/264
Sequence Identity: 36% (42 aa)

KENVIQS----HSLVGTPDYISPEIILGQPHSFTTDYWS-LGVIVYEMLTGAMPFHTESEQHTFKNIVKGIYAPL--TDVSPDAADFVKRLLYSDPRKRL
|||.|.      .. ||| |..|||..|. |. ..| |. ||.. |||..|. ||...  .  ||.|  . .       .||.. |....||  || |||
KENIIKDHDKTKTFCGTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRL

G--CHGPDEILNHPWL
|    . .|| .|||.
GGGPNDAQEIKRHPWF
Kinase 96581.m00100.AA Pkinase_Tyr 318-463 27 4.6e-18 61.81 Pfam 1-158 (270) Show / Hide 
Range on Protein: 318-463
Range on HMM: 1-158/270
Sequence Identity: 27% (44 aa)

FELIERISSGAYARVYLAKKK----LTGDIFAIKVLPKSGLVQKN-QLKRILLEKDILLQF-NNPYVTNFYYSII-GTRN--LYLVMEYIGGGDLFSLLE
 .... . .||. .||... |     |.   |.|.| | |  ...  ..  . |  |. |. ..| . ..|  ..   .   .|.||||  .||| . | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

K----FGCFDEGSARIYTYQIVRALQYLYQNGIIHRDLKPDNILVTSEGYLKLADFGLS
|     . ..      . .|| ....|| ....|||||   |.|||...  | .||||.
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 96581.m00100.AA TyrKc 318-583 20 4.9e-15 20.48 SMART 1-280 (280) Show / Hide 
Range on Protein: 318-583
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

FELIERISSGAYARVYLAKKKLTGDIFAIKVLPKSGLVQKNQLKRILLEKDILLQF--NNPYVTNFYYSIIGT-------RNLYLVMEYIGGGDLFSLLE
 .|.. . .||. .||... |      |.|.| ..       .. .. |  |. ..  ..| . ..|  ..           |..||||  .||| . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

KFGC-FDEGSARIYTYQIVRALQYLYQNGIIHRDLKPDNILVTSEGYLKLADFGLSHLGMKN-RERPNDTIDFRVKENVIQSHSLVGTPD-----YISPE
| .  .       . .|| .  .|| ....|||||   |.||....  | .|||||  .    ..         . . .. . .  |. .       .||
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG--------ESKDYYRKKEHKGGKTMLPIRWMAPE

IILGQPHSFTTDYWSLGVIVYEMLTGAMPFHTE------SEQHTFKNIVKGIYAPLTDV---------SPDAADFVKRLLYSDPRKRLGCHGPDEIL
 |     .. .| || ||  .|..|  .. . .      | |. .... .| . |  .          ...  .  |.    || .|       |..
CINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase 96581.m00100.AA Pkinase_Tyr 515-531 42 6.241465 0.39 Pfam 198-216 (270) Show / Hide 
Range on Protein: 515-531
Range on HMM: 198-216/270
Sequence Identity: 42% (8 aa)

WSLGVIVYEMLT-GAMP-F
|| ||  .|..| |..| .
WSFGVLMWEIFTYGEQPTY