Gene 81529.m00394 (T.vaginalis)

81529.m00394

Species: T.vaginalis
Alias: TvagK0364, 81529.m00394
External Links:
Annotation:

Classification

Group: AGC
Family: NDR
Subfamily: NDR-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
81529.m00394.AA Protein None 482 None Fasta, JSON
81529.m00394.kin_dom Protein Kinase Domain None 287 None Fasta, JSON

Protein domain

Protein domains of 81529.m00394.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 81529.m00394.AA AGC 112-398 28 2.8e-154 402.2 In-house 1-395 (395) Show / Hide 
Range on Protein: 112-398
Range on HMM: 1-395/395
Sequence Identity: 28% (118 aa)

FEKIQIIGRGAFGEVWLVRDK------VDQHIYAMKVLKKKE---LIKKNQILNTIVE------------KDFLVQND----------NPWSVQ-LYFSF
|| . .||.|.||.|.|||.|        ...|||||||||.   ..|||.. .|..|            .. |.. .          .|. |. |..||
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QDPKN--LYLVMEFLP---------GG-DLMNLLV---RRSVLTETETRFLIAE-------AVLAIHCVHM-QGFIHRD-IKPDNLLLTKEGHVRLTDFG
||...  ||.|||..|         || .|.  |    .. ...| ..|| .||        |||..  |  .|.|||| .||.|.||...||..|||||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSTKINRYSDPIVSLIDKITDAFNDFSGNTVDMPYHQKYN----------------------------------KLVCSAVG--TTDYIAPEVLMKKSYG
|....... .. .  ..  .            | .|  .|                                  ..  . .|  | .|.|||.|    ||
LCKEGMNDGEKGQQ-SQ-SN------------MKFHW-HNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YG

PSVDYWS--VGAIMFEMLFGYAPFLSQNPQ----------LTASKIIH----FEQSLIFPPT--------PYVSTEAISLMRGLLT-DADHRLT------
...|.||  .|..|.|||.|| || ..|||           .  ||..    ... . ||.         ...| || .|...||. | ..||.      
KACDWWSFGLGCLMYEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDF

----FEEIKQHPFF
    .||||.||.|
GDKGAEEIKNHPWF
Kinase 81529.m00394.AA NDR 112-398 40 7.50000000001e-145 450.07 In-house 1-350 (350) Show / Hide 
Range on Protein: 112-398
Range on HMM: 1-350/350
Sequence Identity: 40% (143 aa)

FEKIQIIGRGAFGEVWLVRDKVDQHIYAMKVLKKKELIKKNQILNTIVEKDFLVQND--NPWSVQLYFSFQDPKNLYLVMEFLPGGDLMN---LLVRRSV
||.| |||.|||||||||| |  .||||||...|.| ..|||. .   |.| ... |  ||| | ||.||||...||||||..||||.|    ||..  .
FEIIKIIGKGAFGEVWLVRKKDTGHIYAMKIMRKSEMMWKNQVAHVRAERDIMAEADNKNPWVVKLYYSFQDKQYLYLVMEYHPGGDMMTYCYLLMKMDI

LTETETRFLIAEAVLAIHCVHMQGFIHRDIKPDNLLLTKEGHVRLTDFGLSTK--------------------------INRYSDPIVSLIDKITDAFND
.|| ..|| ||| |.||. ||  |.|||||||||.|. | ||. ||||||.|                           ...|.  .  .    . ....
FTEDWARFYIAEMVCAIESVHKMGYIHRDIKPDNFLIDKDGHIKLTDFGLCTGGMIRRHWKQNKQKKPMTTYSTFHWTHNSWYYQNMKEHRPQDFMDNWN

FSGNTVDMPYH-------------------QKYN-KLVCSAVGTTDYIAPEVLMKKS-YGPSVDYWSVGAIMFEMLFGYAPFLSQNPQLTASKIIHFEQS
 ....   . |                   .... .|  |.||| ||.||||...|  |....|.||.|.||.|||.||.||.| .|| |  ||....| 
SNPMNQKCKCHTQMKDQMKCNVKVLNNRSWKQNRRCLAYSTVGTPDYMAPEVFQQKTGYNQTCDWWSLGCIMYEMLVGYPPFCSDTPQETCMKIMNWKQT

L-----IFPPTPYVSTEAISLMRGLLT-DADHRLT-----FEEIKQHPFF
.      |||   .| ||  | | |.. |.||||      ..|||.||||
WDWPMTHFPPEANLSPEAWDLIRRLCCPDPDHRLGSHGKGVDEIKSHPFF
Kinase 81529.m00394.AA MAST 112-398 33 2.2e-97 298.05 In-house 1-337 (337) Show / Hide 
Range on Protein: 112-398
Range on HMM: 1-337/337
Sequence Identity: 33% (112 aa)

FEKIQIIGRGAFGEVWLVRDKVDQHIYAMKVLKKKELIKKNQILNTIVEKDFLVQNDNPWSVQLYFSFQD--PKNLYLVMEFLPGGDLMNLLVRRS-VLT
|| | .|..||.| |.||. |    ..||||...  .|.|||. . .||.. |.. .||. | .. |||    | |..|||.. |||   ||      . 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

ETETRFLIAEAVLAIHCVHMQGFIHRDIKPDNLLLTKEGHVRLTDFGLSTK-INRYSDPIVSL----------------IDKITDAFN-----------D
| .... ||| ||..   | .| .|||.||||.|... ||. ||||||| . ..  .  ...                 |.| .  |            .
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDKTTNHYEGYFNTNIFGKNHFNEYHIQKNYQQFQQDFGINGNTNKN

FSGNTVDMPYHQKYNKL-------VCSAVGTTDYIAPEVLMKKS-YGPSVDYWSVGAIMFEMLFGYAPFLSQNPQL-TASKIIHFEQSLIFPPT------
..      |. |. |..       . . .|| |||||||. ... ||..||.||.| ||.| | |. ||   .|.  . ..||. .  . .|..      
QIQQQQEQPQCQQQNEMRPHNIHQNKQCCGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDD

PYVSTEAISLMRGLLT-DADHRLTFE---EIKQHPFF
  .| ||. |.. ||. .   || .    ||||||||
DCMSPEAQDLIKKLLQPNPKKRLGANGADEIKQHPFF
Kinase 81529.m00394.AA MAST 112-398 31 1e-94 305.73 In-house 1-334 (334) Show / Hide 
Range on Protein: 112-398
Range on HMM: 1-334/334
Sequence Identity: 31% (108 aa)

FEKIQIIGRGAFGEVWLVRDKVDQHIYAMKVLKKKELIKKNQILNTIVEKDFLVQNDNPWSVQLYFSFQDPKNLYLVMEFLPGGDLMNLLVRRSVLTETE
|| | .|..||.| |.||. |    ..||||.|| ..|.||.. . .||.. | . .||. | .. |||  ..|..|||.. |||.  ||     . |  
FEFIKPISKGAYGKVYLVKHKKTNDRFAMKVIKKSDMINKNMVDQVQVERNILAMYQNPFVVKMFYSFQTKNYLCMVMEYMEGGDCASLLHMYGYFDEWM

TRFLIAEAVLAIHCVHMQGFIHRDIKPDNLLLTKEGHVRLTDFGLSTK-INRYSDPIVSL-----IDKITDAFNDFSGNTVDMPYHQKYNKL--------
... ||| ||..   | .| .|||.||||.|....||. ||||||| . ... .  ....     |         | . | .|.. |. ..         
AKMYIAETVLCLEYLHSHGIVHRDLKPDNMLIDSNGHIKLTDFGLSKVGFMDDLNMMYEGYTPPNI---------FNNSTDPMNKNQQDYSQFPGDFGIN

-----------------------------VCSAVGTTDYIAPEVLMKKS-YGPSVDYWSVGAIMFEMLFGYAPFLSQNPQLTASKIIHFE-QSLIFPPT-
                             . . .|| |||||||. ... .|..||.||.| ||.| | |. ||   .|... ..|.. .     .|.. 
GNTNKNQIQQQQEQPQCQQQNMRPHNIHQNKQCCGTPDYIAPEVILGQGTHGKPVDWWSMGIIMYEFLVGCPPFNDDTPEEIFQNILNRNCNEIEWPEGG

-----PYVSTEAISLMRGLLTD-ADHRLTFE----EIKQHPFF
      . | ||. |.. ||.     ||..     |.||||||
DINDDEAMSPEAQDLIEKLLQPDPRKRLGANNGADEVKQHPFF
Kinase 81529.m00394.AA S_TKc 112-398 29 5e-94 319.6 SMART 1-231 (231) Show / Hide 
Range on Protein: 112-398
Range on HMM: 1-231/231
Sequence Identity: 29% (91 aa)

FEKIQIIGRGAFGEVWLVRDKVDQHIYAMKVLKKKELIKKNQILNTIVEKDFLVQNDNPWSVQLYFSFQDPKNLYLVMEFLPG--GDLMNLLVRRSV---
.|....||.||||.|...|.| ...|.|.|..|           ... | . | . . |. |.|| .||| ..||.|||...|  |||. ....|     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---LTETETRFLIAEAVLAIHCVHMQGFIHRDIKPDNLLLTKEGHVRLTDFGLSTKINRYSDPIVSLIDKITDAFNDFSGNTVDMPYHQKYNKLVCSAVG
   ..| ..||.... ..|.   | .|.||||.||.|.||..  |. ..||||....                                       . .|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL--------------------------------------TTFCG

TTDYIAPEVLMKKSYGP-SVDYWSVGAIMFEMLFGYAPFLSQNPQLTASKIIHFEQSLIFPPTPYVSTEAISLMRGLLT-DADHRLTFEEIKQ-------
| .|.|||||   .||. ..| ||.| |..||| || ||   ..|..  ||               | ||....|..|. | ..|.|  |. |       
TPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG--------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKC

HPFF
||.|
HPWF
Kinase 81529.m00394.AA DMPK 112-262 47 3.3e-91 225.45 In-house 1-152 (270) Show / Hide 
Range on Protein: 112-262
Range on HMM: 1-152/270
Sequence Identity: 47% (72 aa)

FEKIQIIGRGAFGEVWLVRDKVDQHIYAMKVLKKKELIKKNQILNTIVEKDFLVQNDNPWSVQLYFSFQDPKNLYLVMEFLPGGDLMNLLVRRS-VLTET
|| . .||||.|||| .|| |  . .||||...|.|..|. .      |.| .|  . .| .||.. |||...||.|||. ||||| .|. |   .. | 
FEILKVIGRGHFGEVQVVRHKQTNDVYAMKMMNKWEMLKRAETACFWEERDIMVHGNSRWITQLHYAFQDENYLYMVMEYMPGGDLLTLMSRYEDRIPED

ETRFLIAEAVLAIHCVHMQGFIHRDIKPDNLLLTKEGHVRLTDFGLSTKINR
 .|| .|| ||||| .|. |..|||||||| || . ||..| |||   |.||
MARFYLAEMVLAIHSIHQMGYVHRDIKPDNMLLDRHGHIKLADFGSCMKMNR
Kinase 81529.m00394.AA RSK 115-398 32 7.8e-84 284.82 In-house 1-278 (278) Show / Hide 
Range on Protein: 115-398
Range on HMM: 1-278/278
Sequence Identity: 32% (100 aa)

IQIIGRGAFGEVWLVRDK---VDQHIYAMKVLKKKELIKKNQ-ILNTIVEKDFLVQND-NPWSVQLYFSFQDPKNLYLVMEFLPGGDLMNLLVRRSV---
..  |.|..|.| |.| .     ..|||||||||.......  .  |  | . |      |  |.|. .||... |||.||...||.|   | ..     
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LTETETRFLIAEAVLAIHCVHMQGFIHRDIKPDNLLLTK---EGHVRLTDFGLSTKINRYSDPIVSLIDKITDAFNDFSGNTVDMPYHQKYNKLVCSAVG
..|.| .| .|| |||. . | ||.||||.||.| |..    |||..|||||.. .                               . ..|..  . ..
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF------------------------------RCDHNQWTMTFCY

TTDYIAPEVLM---KKS-YGPSVDYWSVGAIMFEMLFGYAPFLS---QNPQLTASKIIHFEQSLIFPPTPYVSTEAISLMRGLLT-DADHRLT-----FE
| .|.|||.|.   ... .. ..|.|| |..|.|||.|. || .   .|.. .  .| . . || .|  .|.|.|| .| |..|. |   ||.      |
TIEYMAPEMLKRANQQGGHDKACDWWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAE

EIKQHPFF
||||||.|
EIKQHPWF
Kinase 81529.m00394.AA AktR 112-398 33 1.3e-80 274.17 In-house 1-268 (268) Show / Hide 
Range on Protein: 112-398
Range on HMM: 1-268/268
Sequence Identity: 33% (99 aa)

FEKIQIIGRGAFGEVWLVRDK-VDQHIYAMKVLKKKELIKKNQILNTIVEKDFLV-QNDNPWSVQLYFSFQDPKNLYLVMEFLPGGDLMNLLVRRSVLTE
|. ....|.||||.| ||..|  .| .||||..|||..|..||.  || |.. .  ....|  |.|...||. ..|...||. |||.| . | ..  ..|
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

TETRFLIAEAVLAIHCVHMQ-GFIHRDIKPDNLLLTKEGHVRLTDFGLSTKINRYSDPIVSLIDKITDAFNDFSGNTVDMPYHQKYNKLVCSAVGTTDYI
 ..|| .|. .||.   | .   | ||.||.|.|| ..|||..||||||                              .     |. .  | .||  |.
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSK-----------------------------LQFMMHYDEKAYSFCGTPEYM

APEVLMK-KSYGPSVDYWSVGAIMFEMLFGYAPFLSQNPQLTASKIIHFEQSLIFPPTPYVSTEAISLMRG--LLTDADHRLT-----FEEIKQHPFF
|||...| | .. |||.|..|.  .||..|. || ..| .    ||.  .  . ||...|.| .. .|  .  |  .  .||.     .|||| ||.|
APEMITKKKGHNKSVDWWAFGIFIYEMVTGCPPFYHKNQNQMFQKIKIKQ-QNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 81529.m00394.AA Akt 112-257 43 2e-66 211.33 In-house 1-148 (264) Show / Hide 
Range on Protein: 112-257
Range on HMM: 1-148/264
Sequence Identity: 43% (65 aa)

FEKIQIIGRGAFGEVWLVRDKVDQHIY-AMKVLKKKELIKKNQILNTIVEKDFLVQNDNPWSVQLYFSFQDPKNLYLVMEFLPGGDLMNLLVRRSVLTET
|. . ..|.|.|| | ||..| .| .| |||||||. .|.|||. .|. |.  |.  ..|  |.|..|||....||.||.. .||.| ..| |. . .| 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

ETRFLIAEAVLAIHCVHMQGFIHRD-IKPDNLLLTKEGHVRLTDFGLS
..|| .|| .||| . | .. | ||  || |.|. |.||..||||||.
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLC
Kinase 81529.m00394.AA CRIK 112-262 44 1.9e-56 178.3 In-house 1-152 (272) Show / Hide 
Range on Protein: 112-262
Range on HMM: 1-152/272
Sequence Identity: 44% (68 aa)

FEKIQIIGRGAFGEVWLVRDKVDQHIYAMKVLKKKELIKKNQILNTIVEKDFLVQNDNPWSVQLYFSFQDPKNLYLVMEFLPGGDLMNLLVRRS-VLTET
||   .||.| ||.| .|| |.   ||||||..||..  . |.     |.| .     ||  || . |||  ||||.||. |||||  |. |   .. | 
FEVKDLIGCGHFGQVQVVREKQTNDIYAMKVMHKKVVLAQEQVSFFEEERDIMSRRNSPWLPQLQYAFQDNDNLYLMMEYHPGGDLLSLMNRHDDQFDEN

ETRFLIAEAVLAIHCVHMQGFIHRDIKPDNLLLTKEGHVRLTDFGLSTKINR
  ||  || ..|.| .|  |..||||||.| |.   ||. | |||   |.||
MARFYLAELIVAVHSLHEMGYVHRDIKPENILIDRTGHIKLADFGSAAKMNR
Kinase 81529.m00394.AA ROCK 112-262 49 4.8e-56 189.3 In-house 1-150 (263) Show / Hide 
Range on Protein: 112-262
Range on HMM: 1-150/263
Sequence Identity: 49% (74 aa)

FEKIQIIGRGAFGEVWLVRDKVDQHIYAMKVLKKKELIKKNQILNTIVEKDFLVQNDNPWSVQLYFSFQDPKNLYLVMEFLPGGDLMNLLVRRSVLTETE
|. |..||||||||| |||.|  ...||||.| | |.||.        |.| .     .| |||.. |||.. ||.||...|||||.||.    |  |  
FHMIKVIGRGAFGEVQLVRHKSSKKVYAMKMLSKFEMIKRSDSAFFWEERDIMAHANSEWIVQLHYAFQDDRYLYMVMDYMPGGDLVNLMSNYDV-PEKW

TRFLIAEAVLAIHCVHMQGFIHRDIKPDNLLLTKEGHVRLTDFGLSTKINR
.||  .| |||.  .|  ||||||.||||.|| |.||..| |||   |.|.
ARFYTMEVVLALDAIHSMGFIHRDVKPDNMLLDKYGHLKLADFGTCMKMNK
Kinase 81529.m00394.AA DMPK 300-398 45 4.6e-52 126.45 In-house 160-270 (270) Show / Hide 
Range on Protein: 300-398
Range on HMM: 160-270/270
Sequence Identity: 45% (50 aa)

SAVGTTDYIAPEVL--MKKS----YGPSVDYWSVGAIMFEMLFGYAPFLSQNPQLTASKIIHF-EQSLIFPPTPY--VSTEAISLMRGLLTDADHRLT--
.|||| |||.||||  |       |||..|.|||| .|.|||.|  ||   .   | .|| .. . .| ||. |   ||.|| .| . ||.|...||   
VAVGTPDYISPEVLQAMEDDGKGRYGPECDWWSVGVCMYEMLYGETPFYADSLVETYGKIMNHCKNHLSFPDDPKWDVSEEAKDLICQLLCDREERLGRN

-FEEIKQHPFF
 .|..|.||||
GYEDFKCHPFF
Kinase 81529.m00394.AA Pkinase 173-398 26 2.4e-51 181.67 Pfam 63-293 (293) Show / Hide 
Range on Protein: 173-398
Range on HMM: 63-293/293
Sequence Identity: 26% (70 aa)

VQLYFSFQDPKNLYLVMEFLPGG----DLMNLLV--RRSVL--TETETRFLIAEAVLAIHCVHMQGFIHRDIKPDNLLLTKEGHV----RLTDFGLSTKI
|.|| .|.|....|.|||...||    ||. ..   |. ..  .| | .| . . . ..   | .|.||||.||.|.|. ..||.    ...||||. ..
VRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQF

NRYSDPIVSLIDKITDAFNDFSGNTVDMPYHQKYNKLVCSAVGTTDYIAPEVLM-KKSYGPSVDYWSVGAIMFEMLFGYAPFLSQ------NPQLTASKI
.                                 |    . .|| .|.||||..  . |||.|| ||.| |..|||.|. || ..      ...    .|
D------------------------------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRI

IHFEQSLIFPPTPYVS-----------------TEAISLMRGLLT-DADHRLTFEEIKQHPFF
 . . .  .| .  .|                  |........|. |   |.|.|.|.|||.|
MGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 81529.m00394.AA CRIK 302-398 39 1.6e-30 94.26 In-house 162-272 (272) Show / Hide 
Range on Protein: 302-398
Range on HMM: 162-272/272
Sequence Identity: 39% (44 aa)

VGTTDYIAPEVL--------MKKSYGPSVDYWSVGAIMFEMLFGYAPFLSQNPQLTASKIIH------FEQSLIFPPTPYVSTEAISLMRGLLTDADHRL
||| ||.|||||         | .|| . |.||.| | .||  |  ||   |   | |.|.       |   | ||  | || .. .|.. ||..   ||
VGTPDYMAPEVLQTMNGYKLSKGMYGVDCDWWSMGIIAYEMMCGKTPFHEDNMHRTYSNIMNHCEESHFQRFLSFPDDPKVSPNYRDLIQSLLCNQSKRL

TFEEIKQHPFF
 .| .. ||||
KYEQLCCHPFF
Kinase 81529.m00394.AA ROCK 301-398 43 1.4e-28 94.21 In-house 159-263 (263) Show / Hide 
Range on Protein: 301-398
Range on HMM: 159-263/263
Sequence Identity: 43% (46 aa)

AVGTTDYIAPEVL----MKKSYGPSVDYWSVGAIMFEMLFGYAPFLSQNPQLTASKIIHFEQSLIFPPTPYVSTEAISLMRGLLTDADHRL---TFEEIK
|||| |||.||||        ||  .|.||||  ..|||.|  ||  .    | |||.   .|| ||. . .|..|  |..  |||...||     ..||
AVGTPDYISPEVLKSQGQDGEYGRECDWWSVGVFIYEMLVGDTPFYADSLVGTYSKIMDHKNSLKFPDDVEISKQAKDLICKFLTDREQRLGRNGVDDIK

QHPFF
||.||
QHKFF
Kinase 81529.m00394.AA Akt 303-398 36 1e-24 75.85 In-house 164-264 (264) Show / Hide 
Range on Protein: 303-398
Range on HMM: 164-264/264
Sequence Identity: 36% (38 aa)

GTTDYIAPEVLMKKSYGPSVDYWS-VGAIMFEMLFGYAPFLSQNPQLTASKIIHFEQSLIFPPTPYVSTEAISLMRGLLT-DADHRL-----TFEEIKQH
||  |.|||.| .. .. .|| |. .|..|.||..|  || .|. .    ||  ..| . ||.....| |. .| .|||. | ..||     . .|||.|
GTPEYLAPEILNGNGHTKAVDWWGSLGCVMYEMMCGRPPFYNQDHHQMFKKI--KNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRH

PFF
|.|
PWF
Kinase 81529.m00394.AA TyrKc 112-398 20 2.9e-11 -40.55 SMART 1-280 (280) Show / Hide 
Range on Protein: 112-398
Range on HMM: 1-280/280
Sequence Identity: 20% (66 aa)

FEKIQIIGRGAFGEVWLVRDKVDQHIYAMKVLKKKELIKKNQILNTIVEKDFLVQN--DNPWSVQLYFSFQDP-------KNLYLVMEFLPGGDLMNLLV
 ......|.||||||.. . |      | |.||.        .   . |   . .   ..|  |.||    ..       . |..|||. |.||| . | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RRSV-LTETETRFLIAEAVLAIHCVHMQGFIHRDIKPDNLLLTKEGHVRLTDFGLSTKINRY---SDPIVSLIDKITDAFNDFSGNTVDMPYHQKYNKL-
..   |.  .       .       | ...||||.   | |......|. .||||| .|  .                               ..| .  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQG-------------------------ESKDYYRKK

---VCSAVGTTDYIAPEVLMKKSYGPSVDYWSVGAIMFEML-FGYAPFLS-----QNPQLTASKIIHFEQSLIFPPTPY------VSTEAISLMRGLLTD
    . ..      |||..... . .  | || |  |.|.. .|  |         ..|    .. . .  .  || .|       ..|  ..|.     
EHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYR-MPQPPNDYPMSFVCCPDEMYQIMKQCWHE

-ADHRLTFEEIKQHPFF
 .. | ||.||  | .|
DPEDRPTFSEI--HECF
Kinase 81529.m00394.AA Pkinase 112-154 27 1.2e-10 38.74 Pfam 1-43 (293) Show / Hide 
Range on Protein: 112-154
Range on HMM: 1-43/293
Sequence Identity: 27% (12 aa)

FEKIQIIGRGAFGEVWLVRDKVDQHIYAMKVLKKKELIKKNQI
......||.|.||.|.. ..| ...|.|.|..||..  .. ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQ
Kinase 81529.m00394.AA S_TK_X 399-463 20 4.8e-05 19.87 SMART 1-79 (79) Show / Hide 
Range on Protein: 399-463
Range on HMM: 1-79/79
Sequence Identity: 20% (19 aa)

LGLDWDNLN----KSESPCIPEIS----GDLDTSHFD-NFEPLPEEQDSNTSSESEKEFEDLANI------------------AFMGFQYNK
 |.|||.|     . | | .|.|.    .. ||| ||  |.  .               .. ..                    | || |. 
RGIDWDKLYNQQKEIEPPFKPKIKEVYASPTDTSNFDPEFTEETPM-------------LTPDDPPLSNSMWQNEMETEIPPDPFRGFTYVF
Kinase 81529.m00394.AA Pkinase_Tyr 229-265 40 0.00139 12.76 Pfam 130-164 (270) Show / Hide 
Range on Protein: 229-265
Range on HMM: 130-164/270
Sequence Identity: 40% (15 aa)

QGFIHRDIKPDNLLLTKEGHVRLTDFGLSTKINRYSD
...||||.   | |.|....|. .||||.  |  |.|
KNCIHRDLAARNCLVTENNVVKICDFGLARDI--YND
Kinase 81529.m00394.AA Pkinase_Tyr 112-128 41 0.001775 12.4 Pfam 1-17 (270) Show / Hide 
Range on Protein: 112-128
Range on HMM: 1-17/270
Sequence Identity: 41% (7 aa)

FEKIQIIGRGAFGEVWL
 .... .|.||||||..
ITFGKKLGEGAFGEVYK
Kinase 81529.m00394.AA Pkinase_Tyr 184-204 42 0.525555 4.03 Pfam 81-101 (270) Show / Hide 
Range on Protein: 184-204
Range on HMM: 81-101/270
Sequence Identity: 42% (9 aa)

NLYLVMEFLPGGDLMNLLVRR
..|.|||. |.||| . | ..
QIYIVMEYMPHGDLLDYLRKH