Gene 89842.m00100 (T.vaginalis)

89842.m00100

Species: T.vaginalis
Alias: TvagK0735, 89842.m00100
External Links:
Annotation:

Classification

Group: STE
Family: STE20
Subfamily: MST

Sequence

Name Sequence Type Origin Length Description Download
89842.m00100.AA Protein None 339 None Fasta, JSON
89842.m00100.kin_dom Protein Kinase Domain None 257 None Fasta, JSON

Protein domain

Protein domains of 89842.m00100.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 89842.m00100.AA STE20 33-289 35 1.3e-90 307.39 In-house 1-288 (288) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-288/288
Sequence Identity: 35% (102 aa)

FEIVEEIGKGGFGSVYKVRHRQSGLC----LAGKTINPDVL---TGSASESIVREIELIKKITTAYTIQFYGNIIYNDEP----MLLMEYCDRGSLRDIL
.|..|.||.|..|.|||..|...| .     | | .| .          |.|. ||   |.    . ...||  ...|..     ..||||. |||.||.
YELLEKIGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNEQ-DEWEDIQKEISIMKQCKHPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTDIM

D---FRGE-----TLTEQQAAFVIADLLTAVHILHTKYKILHRDIKAGNILLNSSGQIKVTDFGLSTEFSN-----GKFNTFTPMGTPYWMAPEVING--
.    .|      ...|.| |..  ..| . . || . .| ||||||.||||...|..| .|||..  ...      .|   |  |||||||||||..  
KHCMKCGKNHKGHPMNEEQIAYICREVLQGLDYLHSN-HIIHRDIKADNILLTEDGEVKLADFGVCAQLTKHGRDTMQFKRNTFVGTPYWMAPEVIQCME

---KPYSFPADVWSIAATAIELIEGGPPYYELEPTKAMLKIA--RSGFPGFRN--PKAMSKEFKDFISHTMSRDPNNRCTIPQLLEHPWI
   |.| . .|.||   ||||..|| |||... |..||..|.  . ..| ...  |.  |.||.||...   .||..| |  |||.||.|
GPDKGYDYKCDIWSLGITAIEMAEGEPPYFDMHPMRAMFMIPKNQNPPPTLKDDKPHKWSPEFHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase 89842.m00100.AA S_TKc 33-289 32 3.4e-84 286.94 SMART 1-231 (231) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-231/231
Sequence Identity: 32% (89 aa)

FEIVEEIGKGGFGSVYKVRHRQSGLCLAGKTINPDVLTGSASESIVREIELIKKITTAYTIQFYGNIIYNDEPMLLMEYCDR--GSLRDILDFRGE----
.||...||||.||.|||.||. .|   | | |.         |.| |||.. ||    . ...|. .   |.  . |||||   |.|.|... ||     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

-TLTEQQAAFVIADLLTAVHILHTKYKILHRDIKAGNILLNSSGQIKVTDFGLSTEFSNGKFNTFTPMGTPYWMAPEVINGKPYSF-PADVWSIAATAIE
  ..| .|.|... .. |.  .| . .|.|||.|  ||||..  .||..||||....        |  |||..|||||.   .|.. ..|.||.  . .|
FPFPE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LIEGGPPYYELEPTKAMLKIARSGFPGFRNPKAMSKEFKDFISHTMSRDPNNRCTIPQLLE-------HPWI
.. | ||..     ..|.|. .            |.|.||||.. . .||..| |. ..|.       |||.
MLCGYPPFP---QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 89842.m00100.AA STE 33-289 27 4.1e-82 279.09 In-house 1-359 (359) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-359/359
Sequence Identity: 27% (101 aa)

FEIVEEIGKGGFGSVYKVRHRQ---------------SGLCLAGKTINPDVLT---------------GSASESIVREIELIKKIT--TAYTIQFYGNII
.|..|.||||.||.||| ...                .|   | | .| .  .                .  ..| .||.. ||      . ...||  .
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

YN-------DEPMLLMEYCDRGSLRDILD---FRGETLT----------EQQAAFVIADLLTA-VHILHTKYKILHRDIKAGNILLNSSGQIKVTDFGLS
..       ||  . |||.| |||.||..    .|..|.          |.| |... ..| .  . || .  | |||||..||||     .| .|||..
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH-IIHRDIKPANILL-----VKLCDFGVC

TEFSN----------------GKFNTFTPMGTPYWMAPEVING------KPYSFPADVWSIAATAIELIEGGPPYYELEPTKAMLKIARS----------
. ...                .. .. |  ||| |||||||..      |.|.. .|.||.  |.||...| ||. .. |..||. |...          
GQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQL

-----GFPGFRN-----------------PKAMSKEFKDFISHTMSRDPNNRCTIPQLLE--HPWI
     . | . .                 |. .|.||||||..   .|||.| |  |||.  ||.|
CIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase 89842.m00100.AA MST 33-289 42 1.9e-76 242.5 In-house 1-254 (254) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-254/254
Sequence Identity: 42% (110 aa)

FEIVEEIGKGGFGSVYKVRHRQSGLCLAGKTINPDVLTGSASESIVREIELIKKITTAYTIQFYGNII--YNDEPMLLMEYCDRGSLRDILDFRGETLTE
|.||| .| | .|||||  |.|.|  .| |     | . .  ..|  ||   .     |  ..||. .  .| .  . ||||. ||. ||   .. ||.|
FDIVEKLGQGSYGSVYKAIHKQTGKIVAIKM----VPVNEDLQEIIKEISIMQQCKSKYIVKYYGSYFDAKNNHCWIVMEYCGMGSVCDIMKITQRTLNE

QQAAFVIADLLTAVHILHTKYKILHRDIKAGNILLNSSGQIKVTDFGLSTEFSN--GKFNTFTPMGTPYWMAPEVINGKPYSFPADVWSIAATAIELIEG
|| | .  | |     || . |. ||||||||||||  |  |  ||| | . ..  .| ||.  .|||||||||||.   |   || ||   ||||. ||
QQIACILYDTLQGLQYLH-DNKKIHRDIKAGNILLNHEGECKLADFGVSGQLTDTMAKRNTV--IGTPYWMAPEVIQEIKYDCKADIWSLGITAIEMAEG

GPPYYELEPTKAMLKIARSGFPGFRNPKAMSKEFKDFISHTMSRDPNNRCTIPQLLEHPWI
 ||| .. |. || .|  .  |.|..|   | || ||...   ..|. | |  |||.|| |
MPPYSDIHPMRAMFMIPQKPPPTFKDPEQWSQEFNDFVCKCLQKNPEQRWTAEQLLQHPFI
Kinase 89842.m00100.AA PAKL 33-289 38 9.9e-74 251.26 In-house 1-256 (256) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-256/256
Sequence Identity: 38% (101 aa)

FEIVEEIGKGGFGSVYKVRHRQSGLCLAGKTINPDVLTGS-ASESIVREIELIKKITTAYTIQFYGNIIYN-DEPMLLMEYCDRGSLRDILDFRGETLTE
||. |  | |..|||||. |. ..  || | |    .. |  ...|  ||.. ||    . .  .| |    ..   ||.||  || .|..   . ||.|
FEFQEKLGQGSYGSVYKAIHKDTNFPLAIKVIE---IKESNEIKDIEKEIQILKKCKCPNIVSYFGSIQQKLNHYWILMDYCSLGSINDMMESCCKTLNE

QQAAFVIADLLTAVHILHTKYKILHRDIKAGNILLNSSGQIKVTDFGLSTEFSNGKFN--TFTPMGTPYWMAPEVINGKPYSFPADVWSIAATAIELIEG
 | ....   |   | || |  | |||||| |||||  .|.|. ||| |    .. .        |||||||||.|| ..|   .|.||   ||||. .|
KQISVILQQTLKGLHYLHSK-NIIHRDIKAANILLNEDCQVKIADFGVSQQL-QDEYDGQANQMIGTPYWMAPEIINKQNYNNKCDIWSLGITAIEMADG

GPPYYELEPTKAMLKIARSGFPGFRNPKAMSKEFKDFISHTMSRDPNNRCTIPQLLEHPWI
 || |.. |..||. | .   | | |||  |..| ||.      ||. |    .|| || |
FPPHYDMPPMRAMYMIPNWPPPTFSNPKHWSPCFNDFLAQCCVKDPEKRWSPIDLLCHPFI
Kinase 89842.m00100.AA PAKA 33-289 34 6.3e-68 231.97 In-house 1-260 (260) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-260/260
Sequence Identity: 34% (90 aa)

FEIVEEIGKGGFGSVYKVRHRQSGLC--LAGKTINPDVLTGSASESIVREIELIKKITTAYTIQFYGNIIYNDEPMLLMEYCDRGSLRDILDFRGE----
.. .|.||.|. |.||..  .. .     | |..|  . . .  | |. || . |.      ....   ...||  . ||| . |.| |...   .    
YKFMEKIGQGASGEVYVATNIKTNQEENVAIKQMN--MKNQPKKELIINEILVMKECKHKNIVNYIDSYLVDDELWVVMEYMEGGCLTDVITQCCNIQCN

TLTEQQAAFVIADLLTAVHILHTKYKILHRDIKAGNILLNSSGQIKVTDFGLSTEFSNGKFNTFTPMGTPYWMAPEVINGKPYSFPADVWSIAATAIELI
...|.|.|.|.   | . . .| | .. |||||  ||||.. |..|.||||  .. .  ..   |  |||||||||||..| |.   |.||.   |||.|
YMDEGQIAYVCRECLQGLEFIHSK-HRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQEQQKRNTMVGTPYWMAPEVIRRKQYDEKVDIWSLGIMAIEMI

EGGPPYYELEPTKAMLKIARSGFPGFRNPKAMSKEFKDFISHTMSRDPNNRCTIPQLLEHPWI
|| ||| .  | .||  ||  | | ...|  .|.||.|| .     |. .| .  .||.|| .
EGEPPYLNEPPLRAMYLIATNGKPDIKDPDKWSQEFCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase 89842.m00100.AA Pkinase 33-289 28 3.2e-67 234.42 Pfam 1-293 (293) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-293/293
Sequence Identity: 28% (84 aa)

FEIVEEIGKGGFGSVYKVRHRQSGLCLAGKTINPDVLTGSASESIVR--EIELIKKITTAYTIQFYGNIIYNDEPMLLMEYCDRG----SLRDILD-FRG
..|.. ||.|.||.||| .|. .|   | |.|. .    .  .. .|  ||.. |..   . ...|.   ..|.. . ||||. |    .| |..   |.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

ETL--TEQQAAFVIADLLTAVHILHTKYKILHRDIKAGNILLNSSGQI----KVTDFGLST---EFSNGKFNTFTPMGTPYWMAPEVIN-GKPYSFPADV
 ..  .|... |..  .| ..  .|   .|.|||.|  |||... |.|    |..||||.    . .|. ..||.  |||..||||||. |..|. ..|.
GCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFC--GTPWYMAPEVIRGGQYYGPKVDM

WSIAATAIELIEGGPPYYEL------EPTKAMLKIARSGFPGFRNPK------------------AMSKEFKDFISHTMSRDPNNRCTIPQLLEHPWI
||.  . .|.. | ||...       .. . . .| .  ..  .  .                  ..|.|.||||.    .||. |.|..|.|.|||.
WSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase 89842.m00100.AA SLK 33-289 35 1.2e-66 223.79 In-house 1-259 (259) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-259/259
Sequence Identity: 35% (93 aa)

FEIVEEIGKGGFGSVYKVRHRQSGLCLAGKTINPDVLTGSASESIVREIELIKKITTAYTIQFYGNIIYNDEPMLLMEYCDRGSLRDILDFRGETLTEQQ
.||. |.| | || ||| .|.. ..  | | |  ..  .   |  . ||... ..   . .. |.   |... ....|.|| | .  |.   ...|||.|
WEIIGELGDGAFGKVYKAQHKEQKVFAAAKMI--EIKDEEELEDYMVEIDILSECKHPNIVKLYEAYYYDNKLWMMIEFCDGGAVDNIMVELEHPLTEDQ

AAFVIADLLTAVHILHTKYKILHRDIKAGNILLNSSGQIKVTDFGLSTEFSNGKFNTFTPMGTPYWMAPEVI-----NGKPYSFPADVWSIAATAIELIE
 ..|   .. |.. || . |..|||.||||||.   |.... ||| |    .      | .||||||||||.       .|| . ||.||.  | ||. .
IQYVCKHMCEALNWLHSN-KVIHRDLKAGNILMTMDGDVRLADFGVSAKNKHTMQKRDTFIGTPYWMAPEVVMCETFKDQPYDYKADIWSLGITLIEMAQ

GGPPYYELEPTKAMLKIARSGFPGFRNPKAMSKEFKDFISHTMSRDPNNRCTIPQLLEHPWI
. ||. |..| . .|||..|  |   .|   |||||||. ... .||.|| |  ||..|.|.
MEPPHHEMNPMRVLLKIQKSEPPTLEQPSHWSKEFKDFLKKCLVKDPQNRWTTAQLMQHQWV
Kinase 89842.m00100.AA CAMK 38-289 20 5.3e-61 195.01 In-house 1-425 (425) Show / Hide 
Range on Protein: 38-289
Range on HMM: 1-425/425
Sequence Identity: 20% (89 aa)

EIGKGGFGSVYKVRHRQSG------------LCLAGKTINPDVLT--------------------------GSASESIVREIELIKK-------ITTAYT
..|.|.|| |....|....               | | |. . |.                          ..  ... ||||. ||       .     
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

IQFYG-----------NIIY---------NDEPMLLM---EYCDRG----SLRDILDFRGE--------------TLTEQQAAFVIADLLTAVHILHTKY
|..|            |. |         ...  . |   |||. |     | | .  .|                .||..|....  .. ||| .| . 
IKLYEVYEDPHYFKNTND-YETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHN

KILHRDIKAGNILLNSS-----------------GQIKVTDFGLSTEFSNGKFN-----------------------TFTPMGTPYWMA-PEVING----
 | |||.|  ||||...                 ..||..|||....|  |. |                         |. |||. || |||.||    
-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHC

----------KPYSFPADVWSIAATAIELIEGGPPYYEL-------------EPTKAMLKIARSGF--PGFRNPK-------------------AMSKEF
          ..|....|.||.      .  | ||.|.              .. . . || .  .  | .  ..                     |.| 
NMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQEC

KDFISHTMSRDPNNRCTIPQLLEHPWI
||.|.. . .||..| || | |.|||.
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase 89842.m00100.AA YSK 33-289 35 6.5e-61 181.99 In-house 1-257 (257) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-257/257
Sequence Identity: 35% (93 aa)

FEIVEEIGKGGFGSVYKVRHRQSGLCLAGKTINPDVLTGSASESIVREIELIKKITTAYTIQFYGNIIYNDEPMLLMEYCDRGSLRDILDFR--GETLTE
| . | ||.| || |||   .. .   | |.|. .       | | .||         |  ..||           ||||  ||..| .  .  |. . |
FTKQECIGRGSFGEVYKGIDNRTQRVVAIKIIDLEHAEDEI-EDIQQEIQFLSQCDSPYITKYYGSYLKDTKLWIIMEYCGGGSCLDLMKPKYVGQ-FDE

QQAAFVIADLLTAVHILHTKYKILHRDIKAGNILLNSSGQIKVTDFGLSTEFS--NGKFNTFTPMGTPYWMAPEVING--KPYSFPADVWSIAATAIELI
.. |...  .| .   ||   || |||||| |.||. .|..|. ||| .        | |||   |||||||||||      | | ||.||.  ||.|. 
KYIAIILREILKGLDYLHSERKI-HRDIKAANVLLSEHGDVKLCDFGVAGQITDTQIKRNTF--VGTPYWMAPEVICQEVSYYDFKADIWSLGITAYEMA

EGGPPYYELEPTKAMLKIARSGFPGFRNPKAMSKEFKDFISHTMSRDPNNRCTIPQLLEHPWI
 | |||....| ..|  |  .  |     .  || ||.|.      ||..| .  .|| |  |
KGEPPYCDYHPMRVMFLIPKNNPPKLEG-RSYSKMFKEFVECCLNKDPEQRPSAKELLKHKFI
Kinase 89842.m00100.AA KHS 33-289 35 2e-58 195.08 In-house 1-258 (258) Show / Hide 
Range on Protein: 33-289
Range on HMM: 1-258/258
Sequence Identity: 35% (92 aa)

FEIVEEIGKGGFGSVYKVRHRQSGLCLAGKTINPDVLTGSASESIVREIELIKKITTAYTIQFYGNIIYNDEPMLLMEYCDRGSLRDILDFRGETLTEQQ
.|..  .| | .| ||| |. ||.   | | |   .  |   ..| .|| ..|.   .  . ..|  . .|   . ||||  ||| ||    |. |.| |
YELLQRVGSGTYGDVYKARDIQSDELAAVKVIK--MEPGDDFAVIQQEIMMMKDCRHPNIVAYFGSYLRRDKLWICMEYCGGGSLQDIYHVTGP-LSELQ

AAFVIADLLTAVHILHTKYKILHRDIKAGNILLNSSGQIKVTDFGLSTEFSNGKFNTFTPMGTPYWMAPEVINGKP---YSFPADVWSIAATAIELIEGG
 |.|  . |...| ||.. |. |||||  ||||...|..|. |||.|.. .         .||||||||||   .    |    |.|..  ||||| |  
IAYVCRETLQGLHYLHSMGKM-HRDIKGANILLTDQGDVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAVGITAIELAELQ

PPYYELEPTKAMLKIARSGF--PGFRNPKAMSKEFKDFISHTMSRDPNNRCTIPQLLEHPWI
|| ..| | .|.. ...|.|  |  .. .  |. | .|.  .. ..|  | |  .||.||..
PPMFDLHPMRALFLMTKSNFQPPKLKDKHKWSQTFHHFVKMALTKNPKKRPTAEKLLQHPFV
Kinase 89842.m00100.AA Ste20-DD1 106-289 40 2.9e-53 180.84 In-house 82-268 (268) Show / Hide 
Range on Protein: 106-289
Range on HMM: 82-268/268
Sequence Identity: 40% (76 aa)

MLLMEYCDRGSLRDILDFRGETLTEQQAAFVIADLLTAVHILHTKYKILHRDIKAGNILLNSSGQIKVTDFGLSTEFSNGKFNTFTPMGTPYWMAPEVIN
|  ||||| ||. ||..  . .|.| | | ...        || . .|.||||||||.|.|  || |  ||| ||   |  |   |  | ||||.||.| 
MIVMEYCDGGSILDIMQMCSKRLIEEQIAAICYQIVKGLVYLHSN-RITHRDIKAGNVLVNKEGQPKLADFGVSTIAVNQGFKMNTVIGSPYWMSPEIIM

G----KPYSFPADVWSIAATAIELIEGGPPYYELEPTKAMLKIARSGFPGFRNPKAMSKEFKDFISHTMSRDPNNRCTIPQLLEHPWI
.    . |   ||.||   ||||. |  || ... | .    |     |  . |   | || |||.  ....|  |    ||| || |
PPKGSQGYDQKADIWSLGITAIEMAESKPPRFNVNPVRVIFVIPHQQPPTLKIPSNWSPEFNDFIKQCLNMNPDKRPSAQQLLNHPFI
Kinase 89842.m00100.AA TyrKc 33-292 20 8.8e-16 32.49 SMART 1-280 (280) Show / Hide 
Range on Protein: 33-292
Range on HMM: 1-280/280
Sequence Identity: 20% (61 aa)

FEIVEEIGKGGFGSVYKVRHRQSGLCLAGKTINPDVLTGSASESIVREIELIKKI--TTAYTIQFYGNIIYN-------DEPMLLMEYCDRGSLRDILDF
 .  ...| | || ||| . .   .  | |....|       | . ||... .|.       ...|| ..         . .|..|||.. |.|.| |  
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

RGETLTEQQAAFVIADLLTAVHILHTKYKILHRDIKAGNILLNSSGQIKVTDFGLSTEFSNG-KF----NTFTPM---GTP-----YWMAPEVINGKPYS
....|. ..      .       || | .. |||. | |.|... ...|..||||| .  .. .      . ...   |.       |||||.|| . ..
HRPKLCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

FPADVWSIAATAIELIE-GGPPYYE-----LEPTKAMLKIARSGFPGFRNPKA------MSKEFKDFISHTMSRDPNNRCTIPQLLEHPWIQQI
.  ||||   .  |.   |..||..     .... .. .. . . .             ...|  . ..    .||..|.|  ..     ....
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI-----HECF
Kinase 89842.m00100.AA Pkinase_Tyr 33-132 23 2.1e-08 29.09 Pfam 1-112 (270) Show / Hide 
Range on Protein: 33-132
Range on HMM: 1-112/270
Sequence Identity: 23% (26 aa)

FEIVEEIGKGGFGSVYKVRHR----QSGLCLAGKTINPDVLTGSA--SESIVREIELIKKI-TTAYTIQFYGNIIYNDEP---MLLMEYCDRGSLRDILD
 .. ...|.| ||.||| . .    . ..  | |.. ..  . ..  .|.  ||... |..      ...|| ..  .||   .. |||.  |.|.| | 
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

FR---GETLTEQQ
 .   .. || ..
KHREDKQPLTMKD
Kinase 89842.m00100.AA Pkinase_Tyr 198-286 27 9e-06 20.17 Pfam 180-269 (270) Show / Hide 
Range on Protein: 198-286
Range on HMM: 180-269/270
Sequence Identity: 27% (25 aa)

WMAPEVINGKPYSFPADVWSIAATAIELIE-GGPP-YYELEPTKAMLKIARSGFPGFRNPKAMSKEFKDFISHTMSRDPNNRCTIPQLLEH
|||||.|| . ..   ||||   .  |..  |. | |... ..  . .|...|    . |.  ..|  | . . .  ||..| |  ...|.
WMAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPC-PENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQ
Kinase 89842.m00100.AA Pkinase_Tyr 152-179 39 5e-05 17.64 Pfam 131-158 (270) Show / Hide 
Range on Protein: 152-179
Range on HMM: 131-158/270
Sequence Identity: 39% (11 aa)

KILHRDIKAGNILLNSSGQIKVTDFGLS
.. |||. | |.|.......|..||||.
NCIHRDLAARNCLVTENNVVKICDFGLA
Kinase 89842.m00100.AA Ste20-DD1 33-47 66 0.01271 4.57 In-house 1-15 (268) Show / Hide 
Range on Protein: 33-47
Range on HMM: 1-15/268
Sequence Identity: 66% (10 aa)

FEIVEEIGKGGFGSV
| ||| || | || |
FQIVEVIGQGSFGVV