96726.m00118

Species: T.vaginalis
Alias: TvagK0129, 96726.m00118
External Links:
Annotation:

Classification

Group: Other
Family: Aur

Sequence

Name Sequence Type Origin Length Description Download
96726.m00118.AA Protein None 292 None Fasta, JSON
96726.m00118.kin_dom Protein Kinase Domain None 251 None Fasta, JSON

Protein domain

Protein domains of 96726.m00118.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase 96726.m00118.AA Aur 34-284 59 8.99999999999e-224 597.79 In-house 1-257 (257) Show / Hide
Range on Protein: 34-284
Range on HMM: 1-257/257
Sequence Identity: 59% (152 aa)

FEIGRPLGTGKFGRVYLAREKRTKFIVALKVLDKAEIKKSEVEHQIKREIEIQAHLKHPNVLRLYGYFYDKTRVYLILEYASGGELFRSLREK--HHFDN
||||.||| ||||.|||||.| |.||.||||..| .|||...|||..|||.|| ||.|||.|..||||.|..|.|||||||.||||.. |. .  . || 
FEIGKPLGKGKFGNVYLARHKKTHFIFALKVMFKEQIKKYCMEHQLRREIKIQSHLNHPNILKMYGYFHDDQRIYLILEYAPGGELYKELQKQPNKRFDE

TTAAKYIYQMCNAIIYLHSKHVIHRDIKPENILIG-SNGDLKIADFGWSVHAPFS-RRTTLCGTLDYLPPEMISGEEHDASVDIWSLGVLLYEFLVGAPP
 .||||.||.|||..|.|||..|||||||||||.. .||..||.|||||||.|.. ||.|.||||||.||||..|..|| .||||.||||.||...|.||
QRAAKYMYQICNALDYCHSKNIIHRDIKPENILLDQCNGNIKICDFGWSVHCPNNNRRMTFCGTLDYMPPEMVEGQMHDHKVDIWCLGVLCYELCHGCPP

FEC-ADQETTCERIK-EAKFDFPDSIDEDARDLISSFLQRDPSKRITLESAIEHPWI
||   .. .| .||| . ...||..| ..|.||||  ||.||..|.||. . .||||
FESNENHDETYDRIKNKVDIQFPSHISKEAKDLISKILQHDPKQRMTLDQIMNHPWI

Kinase 96726.m00118.AA AGC 34-284 24 3.2e-126 328.0 In-house 1-395 (395) Show / Hide
Range on Protein: 34-284
Range on HMM: 1-395/395
Sequence Identity: 24% (97 aa)

FEIGRPLGTGKFGRVYLAREK------RTKFIVALKVLDKAE-IKKSE--VEHQIKRE------------IEIQAHLK----------HPNVLR-LYGYF
||. ...|.| ||.|||.|.|       |. . |.|||.|.. |.. .   ......|             .| ....          ||.. . |.  |
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

YDKTR--VYLILEYAS---------GG-ELFRSLR---EKHHFDNTTAAKYIYQ-------MCNAIIYLHS-KHVIHRD-IKPENILIGSNGDLKIADFG
 ||..  .|...||..         || ||| .|.    . .||  .|  |. .       .. |. |||| ...|||| .||||||. ..| .|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

WSVHAPFS----------------------------------------------------RRTTLCG--TLDYLPPEMISGEEHDASVDIWS--LGVLLY
 .   . .                                                    | .|.||  | .|..||..    .. ..|.||  ||.|.|
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

EFLVGAPPFECA----------DQETTCERIK------EAKFDFP----------DSIDEDARDLISSFLQRDPSKRIT----------LESAIEHPWI
|.|.| |||             ... . ..|.      . |  ||          ......|.|||. .|..||.||..           |   .||| 
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF

Kinase 96726.m00118.AA S_TKc 34-284 35 1.4e-108 367.96 SMART 1-231 (231) Show / Hide
Range on Protein: 34-284
Range on HMM: 1-231/231
Sequence Identity: 35% (95 aa)

FEIGRPLGTGKFGRVYLAREKRTKFIVALKVLDKAEIKKSEVEHQIKREIEIQAHLKHPNVLRLYGYFYDKTRVYLILEYASG--GELFRSLREKHH---
.||.|..| | ||.||..|.|.|. |||.|...           .|.|||.|  . .|||. .||..|.| ...|...||..|  |.||. .... .   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FDNTTAAKYIYQMCNAIIYLHSKHVIHRDIKPENILIGSNGDLKIADFGWSVHAPFSRRTTLCGTLDYLPPEMISGEEHDA-SVDIWSLGVLLYEFL
   |.  .|..|.||.|.|. |.||...||||.||||||. .   .||.||| . .      ||.|||..|..||..    ..  ..|.||.|..|||.|
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

VGAPPFECADQETTCERIKEAKFDFPDSIDEDARDLISSFLQRDPSKRITLESAIE-------HPWI
.| |||.  ..... ..|.          ...|.|.|.  ||.||.||.|   | .       |||.
CGYPPFP--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase 96726.m00118.AA CAMK 39-284 23 2.7e-103 333.73 In-house 1-425 (425) Show / Hide
Range on Protein: 39-284
Range on HMM: 1-425/425
Sequence Identity: 23% (101 aa)

PLGTGKFGRVYLAREKRTK------------FIVALKVLDKAEIKKSE-------------------------VEHQIKREIEIQAH-------LKHPNV
 ||.| || |.|...|.|.              || |..||  .|...                          .....|||||  .       |.|||.
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

LRLYGYFYD-------------------KTRVYLIL---EYASGGEL----FRSLREKHH---------------FDNTTAAKYIYQMCNAIIYLHSKHV
..|| .. |                   ....|...   ||.|||||    |  ..|. .               |.   |..|. |.| |. |.||...
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHRDIKPENILIGSN-----------------GDLKIADFGWSVHAPFSR-------------------------RTTLCGTLDYLP-PEMISG------
.|||.||||||. .|                 ...||.||| . . . .                           .| |||. | . ||...|      
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM

--------EEHDASVDIWSLGVLLYEFLVGAPPFECA-------------DQETTCERIKEAKFDFPDS------------------------IDEDARD
        . .. ..|.||.||.||  |.| |||.               ... ..|.|...|.|||..                        ......|
QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD

LISSFLQRDPSKRITLESAIEHPWI
||.. ||.||.||.|.| . .|||.
LIRKMLQVDPEKRMTIEQCLNHPWM

Kinase 96726.m00118.AA CAMKL 34-284 33 8.2e-100 319.21 In-house 1-297 (297) Show / Hide
Range on Protein: 34-284
Range on HMM: 1-297/297
Sequence Identity: 33% (101 aa)

FEIGRPLGTGKFGRVYLARE-KRTKFIVALKVLDKAEIKKSEVEHQ------------IKREIEIQAHLK---HPNVLRLYGYFYDKTR------VYLIL
..||. ||.| || | ||.  . |.  || |..||  |.. .. ..            |.|||.|. .|.   |||. .||  .....       .||..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYASGGE--LFRSLREKHH----FDNTTAAKYIYQMCNAIIYLHSKHVIHRDIKPENILIGSNGD--LKIADFGWS-----V-HAPFSRRTTLCGTLDYL
||.||||  ||  .... |    ..   | .|  |.. |. |.||....||||||||||. .||.  .||.||| |     .   |    .| ||.. | 
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYM

PPEMISG--EEHD-ASVDIWSLGVLLYEFLVGAPPFECA--------DQETTCERIKEAKFDFP--DSIDEDARDLISSFLQRDPSKRITLESAIEHPWI
.||...|  ...|   |||||.||.||  ..|. ||...        .. .  ..|..  . .|   ... |.||||.. ||..|.||.|..   .||| 
APEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM





Kinase 96726.m00118.AA Pkinase 34-284 35 1e-98 339.02 Pfam 1-293 (293) Show / Hide
Range on Protein: 34-284
Range on HMM: 1-293/293
Sequence Identity: 35% (104 aa)

FEIGRPLGTGKFGRVYLAREKRTKFIVALKVLDKAEIKKSEVEHQIK-REIEIQAHLKHPNVLRLYGYFYDKTRVYLILEYASGG----ELFRSLR--EK
..|||..| | ||.||....| |  |||.|...| ..|... .. .. .||.| ..|.|||..|||..|.||...|...||. ||    .||. ..  ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

HHF--DNTTAAKYIYQMCNAIIYLHSKHVIHRDIKPENILIGSNGDL----KIADFGWSV---HAPFSRRTTLCGTLDYLPPEMIS-GEEHDASVDIWSL
  |  .  .. .|.||.. .. |.||. .||||.||||||| .||..    ||.||| .    . . |  ||.|||..|..|| |  |.... .||.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVLLYEFLVGAPPFECA------DQETTCERIKEAKFDFPDSID---------------------EDARDLISSFLQRDPSKRITLESAIEHPWI
|..|||.| | |||  .      ||    .||......|. . .                     |...|.|.. |..||.||.| | . .|||.
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF

Kinase 96726.m00118.AA MARK 34-284 36 3.9e-93 304.76 In-house 1-262 (262) Show / Hide
Range on Protein: 34-284
Range on HMM: 1-262/262
Sequence Identity: 36% (96 aa)

FEIGRPLGTGKFGRVYLAREKRTKFIVALKVLDKAEIKKSEVEHQIKREIEIQAHLKHPNVLRLYGYFY--DKTR-VYLILEYASGGELFRSLREK--HH
..... .|.| .. |.||. |.|.  ||.|...|  . . .    ..|||||  .|.|||. .|. ..   .... .|||.||||||||.  ....  ..
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

FDNTTAAKYIYQMCNAIIYLHSKHVIHRDIKPENILIGSNG--DLKIADFGWSVHAPFSR-RTTLCGTLDYLPPEMISGEEHD-ASVDIWSLGVLLYEFL
     | ..  |.. |. |.|||...||||||||||| .||  . ||.|||.|.. |  .  .| |||. | .||...... |   ||||||||.||  .
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFMV

VGAPPFE--CADQETTCERIKEAKFDFPDSIDEDARDLISSFLQRDPSKRITLESAIEHPWI
.|  ||.  ..|...  ..|   |.|.|. .  ..|.||...|. .|..|.|.|   .|||.
CGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM

Kinase 96726.m00118.AA RSK 37-284 34 2.9e-89 302.86 In-house 1-278 (278) Show / Hide
Range on Protein: 37-284
Range on HMM: 1-278/278
Sequence Identity: 34% (96 aa)

GRPLGTGKFGRVYLAREK---RTKFIVALKVLDKAEIKKSEV-EHQIKREIEIQAHLK-HPNVLRLYGYFYDKTRVYLILEYASGGELFRSLREKHH---
 . ||.| .| |.| |..    |. | | |||.||.|.....     ..|..| .. . ||.. .|.  | ... .|||.|| .|||||. |... |   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FDNTTAAKYIYQMCNAIIYLHSKHVIHRDIKPENILIGS---NGDLKIADFGWSVHAPFS---RRTTLCGTLDYLPPEMIS----GEEHDASVDIWSLGV
|. ..|. |...   |. .||....||||.||||||  .   .| .|. ||| .  .. .   .  | |.|..|..|||.     .. ||...|.|||||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

LLYEFLVGAPPFEC---ADQETTCERIKEAK--FDFP--DSIDEDARDLISSFLQRDPSKRIT-----LESAIEHPWI
|.|| |.|.|||     .... . .||...|  ...|  ... ..|.|||.  |.|||.||..     .|   .|||.
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF

Kinase 96726.m00118.AA Ciliate-E2 34-284 27 5.5e-88 298.62 In-house 1-365 (365) Show / Hide
Range on Protein: 34-284
Range on HMM: 1-365/365
Sequence Identity: 27% (103 aa)

FEIGRPLGTGKFGRVYLAREKRTK-----------------------FIVALKVLDKAEIKKSEVEHQIKREIE----------IQAHLKHPNVLRLYGY
... . .|.| || ||... ....                       .|.|.|.. | .|.  . | .| |||.          |. .|.|||....| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FY--DKTRVYLILEYASGGELFR-----SLREKHH------FDNTTAAKYIYQMCN---------------AIIYLHSKH-VIHRDIKPENILIGSNGDL
|.  |.. .||..||..||.||      .. ..|.      |.   ......| ..               |. |||||. .|||||||||||.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KIADFGWSVHAPFSRR---------------------------------TTLCGTLDYLPPEMISGEE---------HDASVDIWSLGVLLYEFLVGAPP
||.||| |  .  ..                                   |.|||. |..||...|..         .| ..|||||||.|||.| | ||
KIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKPP

FECADQETTCERIKEAKFDFP------------------DSIDEDARDLISS----FLQRDPSKRIT-LESAIEHPWI
|         . ||. |.|||                  ....... |||.      ||.||.||||  | ...|||.
F--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF

Kinase 96726.m00118.AA PLK 34-284 34 6.6e-85 276.43 In-house 1-258 (258) Show / Hide
Range on Protein: 34-284
Range on HMM: 1-258/258
Sequence Identity: 34% (90 aa)

FEIGRPLGTGKFGRVYLAREKRTKFIVALKVLDKAEIKKSEVEHQIKREIEIQAHLKHPNVLRLYGYFYDKTRVYLILEYASGGELFRSLREK-HHFDNT
.|.|..|| | | ..| ...  || ..| || .|. ..|.     .|.||||.  |.|||..... .| |.  ||. |||.....|.. .. . ...  .
YERGHFLGKGGFAKCYEMTDIHTKQVYAIKVVPKSLMQKPHQREKMKQEIEIHRQLHHPNIVKFHHFFEDHENVYIVLEYCHNRSLMHYHKRRAKRLTEP

TAAKYIYQMCNAIIYLHSKHVIHRDIKPENILIGSNGDLKIADFGWSVHAPF--SRRTTLCGTLDYLPPEMISGEE--HDASVDIWSLGVLLYEFLVGAP
 .  |.|| .... |||.. .||||.|. |... .|  .||.||| ..   .   |. |.|||  |  ||   | .  |.  ||.||||. .| .|.| |
EVRYYMYQIVQGLKYLHQHRIIHRDLKLGNLFLNDNMHVKIGDFGLATRLEYDGERKKTMCGTPNYIAPEVLDGNKQGHSYEVDCWSLGCIMYTLLIGKP

PFECADQETTCERIKEAKFDFPDS--IDEDARDLISSFLQRDPSKRITLESAIEHPWI
||| .| ..| .|||.... ||..  |   |.||| . |...|..|.|..  ..||. 
PFETKDVKETYKRIKHNHYSFPEHCPISDEAKDLIQKMLNWNPDERPTIDQILQHPFF

Kinase 96726.m00118.AA PKA 34-284 41 1.1e-82 281.02 In-house 1-263 (263) Show / Hide
Range on Protein: 34-284
Range on HMM: 1-263/263
Sequence Identity: 41% (109 aa)

FEIGRPLGTGKFGRVYLAREKRTKFIVALKVLDKAEIKKSEVEHQIKREIEIQAHLKHPNVLR-LYGYFYDKTRVYLILEYASGGELFRSLREKHHFDNT
||| . |||| ||||.|.|.| .. ..|.|.|.|.||..   .. .. |. |   .|||.. . .|. | | .  |...||..|||.|  || . .|.| 
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

TAAKYIY-QMCNAIIYLHSKHVIHRDIKPENILIGSNGDLKIADFGWSVHAPFSRRTTLCGTLDYLPPEMISGE-EHDASVDIWSLGVLLYEFLVGAPPF
.|  |.  | . |. ||||.. |.|| ||||||| .|| .||.||| .      |  ||||| .||.||.|...  |  ||| |.||.| ||.|.| |||
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD-RTWTLCGTPEYLAPEIIQSKNGHGKSVDWWALGILIYEMLAGYPPF

ECA--DQETTCERIKEAKFDFPDSIDEDA---RDLISSFLQRDPSKRI-TLES----AIEHPWI
.    |.  . |.| ..| .|| ..| ||   .|||.. ||.|..||. ....      .|.| 
YDHNRDPMQIYEKICNGKIKFPRHFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF

Kinase 96726.m00118.AA Ciliate-E2-Unclassified 34-284 27 7.2e-80 271.66 In-house 1-352 (352) Show / Hide
Range on Protein: 34-284
Range on HMM: 1-352/352
Sequence Identity: 27% (96 aa)

FEIGRPLGTGKFGRVYLAREKRTKFIVALKVLDKAEIKK-----SEVEHQIKREIEIQAH------------------LKHPNVLRLYGYFYDKTRVYLI
..|.. .|.| || ||....| .|.. |.| . |. |.|     ..    .  ..|.. .                  ..||...... .| ||  .|..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LEYASGG-----------------ELFRSLREKHHFDNTTAA-----KYIYQMCNAIIYLHSKH-VIHRDIKPENILIGSNG---DLKIADFGWSVHA--
.||. ||                 .||........|.   |.     .|..| .... |||.|. .|||||||||||. .||    .||.||| | .   
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

---------------PFSRRTTLCGTLDYL----PPEMISGEEHDAS----VDIWSLGVLLYEFLVGAPPFECADQET----------------TCERIK
               .. . .| |||. |.    .||.. |...| |    .|||||||.|||.| | .||.. ..|                   . ||
NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK

EAKFDFP--------DSIDEDARDLIS----SFLQRDPSKRITLESAIEHPWI
. ...||        . ... | |.|.    . |. .|.||||.| ...|||.
QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF

Kinase 96726.m00118.AA Pkinase_Tyr 34-177 33 4.2e-30 102.58 Pfam 1-156 (270) Show / Hide
Range on Protein: 34-177
Range on HMM: 1-156/270
Sequence Identity: 33% (52 aa)

FEIGRPLGTGKFGRVYLAREK----RTKFIVALKVLDKAEIKKSE-VEHQIKREIEIQAHL-KHPNVLRLYGYFY-DKTR--VYLILEYASGGELFRSLR
 ..|. || | ||.||... |     ||  || |.| |    ...       ||..|  .| .|||..||||  . ..    .|...||. .| |   ||
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

E----KHHFDNTTAAKYIYQMCNAIIYLHSKHVIHRDIKPENILIGSNGDLKIADFG
.    |....  .  .. .| ...  ||.||. ||||.   |.|...|.  ||.|||
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG

Kinase 96726.m00118.AA TyrKc 34-279 23 1.4e-21 78.9 SMART 1-280 (280) Show / Hide
Range on Protein: 34-279
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

FEIGRPLGTGKFGRVYLAREKRTKFIVALKVLDKAEIKKSEVEHQIKREIEIQAHL--KHPNVLRLYGYFYDK-------TRVYLILEYASGGELFRSLR
 . |. || | ||.||... |     || |.| .        .  . ||..|  .|  .|||..||||.  ..         .....||...| |   ||
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

EKHH-FDNTTAAKYIYQMCNAIIYLHSKHVIHRDIKPENILIGSNGDLKIADFGWSVHAPFS-------RRTTL----CGT----LDYLPPEMISGEEHD
.... . . .  .. .| ..   |||||..||||.   |.|.|.|.  ||.||| |                .     .|     .  ..|| |   .  
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

ASVDIWSLGVLLYEFL-VGAPPFEC-----ADQETTCERIKEA-KFDFPDS--------IDEDARDLISSFLQRDPSKR---ITLESAI
   |.|| ||...| .  |..| .       . .   |..|.    . |..          ..  .....  ..||..|    .. . .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase 96726.m00118.AA Pkinase_Tyr 212-222 63 1.925541 2.12 Pfam 196-206 (270) Show / Hide
Range on Protein: 212-222
Range on HMM: 196-206/270
Sequence Identity: 63% (7 aa)

DIWSLGVLLYE
|.|| |||..|
DVWSFGVLMWE