Gene 95311.m00044 (T.vaginalis)

95311.m00044

Species: T.vaginalis
Alias: 95311.m00044, TvagK0434
External Links:
Annotation:

Classification

Group: AGC
Family: Akt

Sequence

Name Sequence Type Origin Length Description Download
95311.m00044.AA Protein None 429 None Fasta, JSON
95311.m00044.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of 95311.m00044.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PH 95311.m00044.AA PH 8-104 19 1.3e-07 32.49 SMART 1-82 (82) Show / Hide 
Range on Protein: 8-104
Range on HMM: 1-82/82
Sequence Identity: 19% (19 aa)

FAIEGVLMQKTNVFRSDRKLYGIVTEKVFSTFTDEKYQRLYKEISLDDIKSVSLLNGCRPGFTITLEDSDEELSYFCQSKHQAQKWVCALELKPFSN
. .|| |..|.  . . .| . ........ . |.   .. ..|.|.|. .|.       .|.|.  |   ..  .| |. ..|.|. |..    .|
VIKEGWLYKKS--K-RWKKRWFVLFNDCLYYYKDK---KPKGSIPLSDC-TVRE-P----CFEIHH-DR--TYYFQCESEEEMQEWMQAIQKAIHNN
Kinase 95311.m00044.AA AGC 111-365 28 3.4e-138 359.68 In-house 1-395 (395) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-395/395
Sequence Identity: 28% (113 aa)

FEFIKEIGKGGSATVYVARNR------ITNELVAIKCIDKAN-ISSDK--RKEHIQSE------------RNTLMRAR----------HPFIIR-LYNAF
|||.| ||||.  .|| .| .       |... |.|...|.  |  .|    ||...|            || |....          ||||.. |. .|
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

QTNTH--LFFVLEFAH---------GG-DLQFQLERN----CFSEYQKKLYLAE-------IALAVKSLHS-IGIIYRD-LKPENILLDAKGHIKLADFG
|...|  |.||.|..          || .| ..|       .|.| . . |.||       |.||. .|||  |||.|| |||||||||..|||||.|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

TAREVRPDC---------------------------------------------------SCTSFCG--TAEFLAPEVIQGKENQSFAIDWWS--FGVVA
 . |.. |.                                                    ...|||  |.|..|||..      ..| ||||  .|.. 
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL-----YGKACDWWSFGLGCLM

YMFFVGSCPFTSPL----------RTRLFESIV------HKPLRFPP---------KSVDPVTQDFISKLLEKNPAKRLGSPGYD--------IFKHPFW
| . .|  ||..            .  .|..|       .....||.         ....|  .|.|.|||.|.|.||||. | |        | .||. 
YEMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase 95311.m00044.AA S_TKc 111-365 35 1.1e-92 315.18 SMART 1-231 (231) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-231/231
Sequence Identity: 35% (95 aa)

FEFIKEIGKGGSATVYVARNRITNELVAIKCIDKANISSDKRKEHIQSERNTLMRARHPFIIRLYNAFQTNTHLFFVLEFAHG--GDLQFQLERNC----
.|....||||. ..|| .|.. |...||||.|.          |||..|.. |.. .||.|..|| .||. .||..|.|.. |  |||   ....     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGL

---FSEYQKKLYLAEIALAVKSLHSIGIIYRDLKPENILLDAKGHIKLADFGTAREVRPDCSCTSFCGTAEFLAPEVIQGKENQSFAIDWWSFGVVAYMF
   |.| . . |...|..|.. .|| |||.|||||||||||   |||..||| ||..      |.|||| ...||||.       ...||||.|.. | .
RFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEM

FVGSCPFTSPLRTRLFESIVHKPLRFPPKSVDPVTQDFISKLLEKNPAKRLGSPGYDI-----FKHPFW
..|  ||      ..|. |.           .|   |||.|.|.|.|.||..            .||. 
LCGYPPFP--QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase 95311.m00044.AA SGK 111-365 36 2.3e-91 282.37 In-house 1-283 (283) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-283/283
Sequence Identity: 36% (104 aa)

FEFIKEIGKGGSATVYVARNRIT------------------NELVAIKCIDKANIS-------SDKRKEHIQSER-NTLMRARHPFIIRLYNAFQTNTHL
|.|.| ||||.   || ..   .                    . |.| . |. |          |   ||..|| . |   .||||. |  |||| . |
FDFLKVIGKGSFGKVYQVKHKDDETCQRVWLIFQSLLSQSEDKFYAMKVLQKQHIINEYRQDLKKKEQKHIMAERNVILKNMKHPFIVNLHYAFQTKWKL

FFVLEFAHGGDLQFQLER-NCFSEYQKKLYLAEIALAVKSLHSIGIIYRDLKPENILLDAKGHIKLADFGTAR-EVRPDCSCTSFCGTAEFLAPEVIQGK
.||.... ||.. . | | ..|.| . . | |||..|   |||. ||||||||||||||..||..| ||| .  .. .    ..|||| | |||||....
YFVMDYVNGGEMFYHLQREKHFPEDRARFYAAEIVCALEYLHSQDIIYRDLKPENILLDHQGHCCLTDFGLCKEGIKTNDTTFTFCGTPEYLAPEVLRKQ

ENQSFAIDWWSFGVVAYMFFVGSCPFTSPLRTRLFESIVHKPLRFPPKSVDPVTQDFISKLLEKNPAKRLGSP--GYDIFKHPFW
.  . . |||. | | | . .|  || |  .  ... | ..||..|| .. .   | |  ||.|.| ||||.   . .| .||| 
P-HDRTVDWWCLGCVLYEMMYGLPPFYSRNKQQMYDNIINQPLQIPP-QMSNDAWDLIQGLLQKDPKKRLGTKRDFMEIKNHPFF
Kinase 95311.m00044.AA Akt 111-365 40 1.7e-85 273.28 In-house 1-264 (264) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-264/264
Sequence Identity: 40% (108 aa)

FEFIKEIGKGGSATVYVARNRITNELV-AIKCIDKANISSDKRKEHIQSERNTLMRARHPFIIRLYNAFQTNTHLFFVLEFAHGGDLQFQLER-NCFSEY
|.|.| .|||  . |. ..   |...  |.| . |  |   . .||.. ||| | . .||||. |. .|||...|.||.... ||.| . | | . ||| 
FDFLKVLGKGSFGKVFLVKKKDTQKWYYAMKVLKKDYIIQKNQVEHTKTERNILQHCNHPFIVNLHYSFQTQDKLYFVMDYCNGGELFYHLQRKRRFSED

QKKLYLAEIALAVKSLHSIGIIYRD-LKPENILLDAKGHIKLADFGTAR-E-VRPDCSCTSFCGTAEFLAPEVIQGKENQSFAIDWWS-FGVVAYMFFVG
. . | ||| ||   ||| .||||| |||||||.|..|||.|.||| .. . .  .  ...||||.| ||||...|   .. | |||. .|.| | .  |
RARFYCAEIILAIEHLHSKNIIYRDYLKPENILMDKDGHICLTDFGLCKENIIKDHDKTKTFCGTPEYLAPEILNG-NGHTKAVDWWGSLGCVMYEMMCG

SCPFTSPLRTRLFESIVHKPLRFPPK-SVDPVTQDFISKLLEKNPAKRLG-SPG--YDIFKHPFW
  || .  . ..|. |  .|..||.|  ..|  .|.||.||.|.| ||||  |.   .|  ||. 
RPPFYNQDHHQMFKKIKNQPVKFPDKDWISPECKDLISGLLNKDPKKRLGGGPNDAQEIKRHPWF
Kinase 95311.m00044.AA RSK 114-365 37 2.3e-83 283.27 In-house 1-278 (278) Show / Hide 
Range on Protein: 114-365
Range on HMM: 1-278/278
Sequence Identity: 37% (103 aa)

IKEIGKGGSATVYVARNRI---TNELVAIKCIDKANISSDKR-KEHIQSERNTLMRAR-HPFIIRLYNAFQTNTHLFFVLEFAHGGDLQFQLE--RN--C
.|. |.||   |.. |  .   |. . | | ..|| |   ..  .|   ||| |.| . ||||..|. ||||...|. ..|. .||.|   |.  .   |
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

FSEYQKKLYLAEIALAVKSLHSIGIIYRDLKPENILLDA---KGHIKLADFGTAREVRPD--CSCTSFCGTAEFLAPEVIQ---GKENQSFAIDWWSFGV
|||   . |.|||.|||. ||. |||.|||||||||.|     ||||| ||| ... |.|      .||.|.|..|||..    ...  . | ||||.||
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQFRCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDKACDWWSLGV

VAYMFFVGSCPFTS---PLRTRLFESIVHKP--LRFP-PKSVDPVTQDFISKLLEKNPAKRLGSP---GYDIFKHPFW
. |. ..|  ||..     |  ... | ..   |..| .... .  .|.|.|.|...|.||||.      .| .||..
LMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase 95311.m00044.AA Pkinase 111-365 31 3.2e-81 280.92 Pfam 1-293 (293) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-293/293
Sequence Identity: 31% (95 aa)

FEFIKEIGKGGSATVYVARNRITNELVAIKCIDKANISSDKRKEHIQ-SERNTLMRARHPFIIRLYNAFQTNTHLFFVLEFAHGG----DLQFQLE---R
..... ||.|....|| .... |...||.|.|.| ...|.|...|.  ||   . | .||.|.||| .|....|. .|.|.. ||    ||   ..   .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

NCF--SEYQKKLYLAEIALAVKSLHSIGIIYRDLKPENILLDAKGHI----KLADFGTARE--VRPDCSCTSFCGTAEFLAPEVIQGKENQSFAIDWWSF
.||  || . | |. .|. ... .|| |||.|||||||||.| .|||    |..||| |.     ..  .|.|||| ...|||||.| .  . ..|.||.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVVAYMFFVGSCPFTSP------LRTRLFESIVHKPLRFPPKSVD--------------------PVTQDFISKLLEKNPAKRLGSPGYDIFKHPFW
|.. | .. |  || .           ... | ..||.|.    .                    .  .|||...|.|.|.||..    .|..||..
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPT--AEQILQHPWF
Kinase 95311.m00044.AA PKC 111-365 39 1.9e-80 260.41 In-house 1-262 (262) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-262/262
Sequence Identity: 39% (104 aa)

FEFIKEIGKGGSATVYVARNRITNELVAIKCIDKANISSDKRKEHIQSERNTLMRA-RHPFIIRLYNAFQTNTHLFFVLEFAHGGDLQFQLERN-CFSEY
|.|.| .|||  . |  |. . |.|. |||.. | .|  |   |  . |.  |  | .|||   |.  |||. .||||.|.  |||| |.  .   |.|.
FNFLKVLGKGSFGKVMLAERKGTDEYYAIKVLKKDVIIQDDDVECTMTEKRVLALAWKHPFLTHLHCCFQTMDRLFFVMEYVNGGDLMFHIQQQRRFKEE

QKKLYLAEIALAVKSLHSIGIIYRDLKPENILLDAKGHIKLADFGTARE-VRPDCSCTSFCGTAEFLAPEVIQGKENQSFAIDWWSFGVVAYMFFVGSCP
. . | |||..| . ||. |||||||| .|.|||. ||||.|||| . | ....   ..|||| ...|||..|..|  ....|||.|||  | . .|  |
HARFYAAEIICALQFLHEKGIIYRDLKLDNVLLDHEGHIKIADFGMCKENMWNGDTTSTFCGTPDYIAPEILQYQE-YGKSVDWWAFGVLMYEMMAGQSP

FTSPLRTRLFESIVHKPLRFPPKSVDPVTQDFISKLLEKNPAKRLGSPGY------DIFKHPFW
|     . ||.|| |.  .. |..      . ......|||.||||.  .      || .||| 
FHGEDEDELFQSIMHDNPHY-PRWLSKEAVSICKGFMTKNPEKRLGCHPQQEEGEQDIREHPFF
Kinase 95311.m00044.AA Ciliate-E2 111-365 22 1.4e-79 270.67 In-house 1-365 (365) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

FEFIKEIGKGGSATVYVARNRITNE-----------------------LVAIKCIDKANISSDKRKEHIQ----------SERNTLMRARHPFIIRLYNA
..||| ||.|. ..|| .... ...                       ..|.|.. | .| . |...||            |.| | .  ||.||..| .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FQ--TNTHLFFVLEFAHGGDLQF--------------QLERNCFSEYQKKLYLAEIAL---------------AVKSLHSIG-IIYRDLKPENILLDAKG
||  .......|.|.. ||||.               . . ..|.|.. | . ..|.                |...||| . ||.||.||||||.    
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF----

HIKLADFGTAREVRPD--------------------------------CSCTSFCGTAEFLAPEVIQGKEN--------QSFAIDWWSFGVVAYMFFVGS
 ||..|||..... .|                                    ..|||....|||...||..         ....|.||.||. |..  | 
-IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

CPFTSPLRTRLFESIVHK-PLRFP-----------------PKSVDPVTQDFISK----LLEKNPAKRLGSPG-YDIFKHPFW
 ||         . . .. ...||                 .|.... ..|.|.|    .|.|.| ||..  |  .|..||. 
PPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRIT--GWEQILNHPWF
Kinase 95311.m00044.AA AktR 111-365 38 2.7e-79 269.73 In-house 1-268 (268) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-268/268
Sequence Identity: 38% (104 aa)

FEFIKEIGKGGSATVYVARNR-ITNELVAIKCIDKANISSDKRKEHIQSERNTLM-RARHPFIIRLYNAFQTNTHLFFVLEFAHGGDLQFQLE-RNCFSE
|...| .|||. ..|| .. .  .....|.| |.| .|   ....|.. ||| .   ..||||..|. .|||...|||..|.  ||.| . |  .. |||
FHVYKCLGKGAFGKVYLVQKKRDNQKQYAMKMIKKKKIIERNQMHHTITERNIMEMCCNHPFIVKLHYCFQTKEKLFFIMEYCPGGELFQHLKKKKKFSE

YQKKLYLAEIALAVKSLHSI-GIIYRDLKPENILLDAKGHIKLADFGTAR--EVR-PDCSCTSFCGTAEFLAPEVIQGKENQSFAIDWWSFGVVAYMFFV
 | . | |.| ||.  ||.   ||||||||||||||  ||.|..||| ..   ..  |   .||||| | .|||.|. |.   ...|||.||.. |   .
EQARFYFAQILLALEYLHQHMNIIYRDLKPENILLDEDGHVKITDFGLSKLQFMMHYDEKAYSFCGTPEYMAPEMITKKKGHNKSVDWWAFGIFIYEMVT

GSCPFTSPLRTRLFESIVHKP-LRFPP-KSVDPVTQDFIS-KLLEKNPAKRLGSP---GYDIFKHPFW
|  ||..  ....|..|  |. ..||. . . .  .|.|  ||| ||| ||||.      .| .||. 
GCPPFYHKNQNQMFQKIKIKQQNKFPYPSYFSSQCKDLIQRKLLCKNPNKRLGYYCNGWEEIKSHPWF
Kinase 95311.m00044.AA PKA 111-365 36 7.7e-75 254.94 In-house 1-263 (263) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-263/263
Sequence Identity: 36% (98 aa)

FEFIKEIGKGGSATVYVARNRITNELVAIKCIDKANISSDKRKEHIQSERNTLMRARHPFIIR-LYNAFQTNTHLFFVLEFAHGGDLQFQLERN-CFSEY
||.|. .|.|  ..|. .|.... . .|.|...|. |   | .||. .|.| |.  .||||.. .|  ||....|..|.|.. ||...  | .. .||..
FEIIQTLGTGSFGRVMLCRHKHSGNYYAMKMLKKQEIVRLKQVEHVHNEKNILQNIKHPFIVKKMYWTFQDDRYLYMVMEYVPGGEMFSYLRKSGRFSNP

QKKLYLA-EIALAVKSLHSIGIIYRDLKPENILLDAKGHIKLADFGTAREVRPDCSCTSFCGTAEFLAPEVIQGK--ENQSFAIDWWSFGVVAYMFFVGS
. |.| | .| ||   |||  ||||||||||||.| .||||..||| | .|.      . ||| | ||||.||.|   .   ..|||..|.. | . .| 
HAKFYAASQIVLALEYLHSQNIIYRDLKPENILIDKNGHIKITDFGFAKKVDD--RTWTLCGTPEYLAPEIIQSKNGHGK--SVDWWALGILIYEMLAGY

CPFTSP--LRTRLFESIVHKPLRFPPKSVDPVT---QDFISKLLEKNPAKRLGSPGY---DIFKHPFW
 ||.        ..| |.   ..||. ..|.      |.|.|||.... ||.|.      || .|.. 
PPFYDHNRDPMQIYEKICNGKIKFPR-HFDSDANYFKDLIKKLLQVDLTKRYGNMKNGVNDIKNHKWF
Kinase 95311.m00044.AA Ciliate-E2-Unclassified 111-365 25 7.9e-75 254.91 In-house 1-352 (352) Show / Hide 
Range on Protein: 111-365
Range on HMM: 1-352/352
Sequence Identity: 25% (92 aa)

FEFIKEIGKGGSATVYVARNRITNELVAIKCIDKANISSDKRKEH---------IQSERN-------------TLMRARHPFIIRLYNAFQTNTHLFFVL
...|| ||.|| ..|| .... .... |.| . |..| ..| ...         .  ...              |    ||||.... .||.  ....|.
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EFAHGGDLQFQLE------------------RNCFSEYQKK-----LYLAEIALAVKSLHSIG-IIYRDLKPENILLDAKG---HIKLADFGTAREVR--
|.. ||||.. ..                  |..|.|.| |      |.|.| .. ..||. . ||.||.||||||.| .|   .||..||| ...    
EYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQN

--------------PDCSCTSFCGTAEFL----APEVIQGKENQS---FAIDWWSFGVVAYMFFVGSCPFTSPLRTR----------------LFESIVH
              ... ...|||| ...    ||||.||...     ...|.||.||..| .  | .|| .. ..                 |.. |  
NNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQ

KPLRFPP-------KSVDPVTQDFIS----KLLEKNPAKRLGSPGYDIFKHPFW
|.. ||.       | ..|  .|||.    |.|.||| ||.. .  .|..||. 
KNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFE--QILNHPWF
Kinase 95311.m00044.AA MAST 111-253 40 4.1e-57 172.71 In-house 1-147 (337) Show / Hide 
Range on Protein: 111-253
Range on HMM: 1-147/337
Sequence Identity: 40% (59 aa)

FEFIKEIGKGGSATVYVARNRITNELVAIKCIDKANISSDKRKEHIQSERNTLMRARHPFIIRLYNAFQT--NTHLFFVLEFAHGGDLQFQLER-N-CFS
||||| |.||.   || .....||...|.| |.. ..   .  .....|||.|  .  ||.  .. .|||   ..|..|.|. .|||  . |.  . |. 
FEFIKCISKGAYGAVYLVKHKKTNDRFAMKVINCQDTIDKNQVDQVFVERNILTMYQNPFVVKMFYSFQTPCKKYLCMVMEYMEGGDCASLLRMYGNCMP

EYQKKLYLAEIALAVKSLHSIGIIYRDLKPENILLDAKGHIKLADFG
|   |.|.||. |..  ||| ||. |||||.|.|.|..|||||.|||
EWMAKMYIAETVLCLEYLHSYGIVHRDLKPDNMLIDSNGHIKLTDFG
Kinase 95311.m00044.AA MAST 268-365 36 1.6e-27 80.57 In-house 229-337 (337) Show / Hide 
Range on Protein: 268-365
Range on HMM: 229-337/337
Sequence Identity: 36% (40 aa)

CGTAEFLAPEVIQGKENQSFAIDWWSFGVVAYMFFVGSCPFTSPLRTR-LFESIVH--KPLRFPPK-------SVDPVTQDFISKLLEKNPAKRLGSP-G
||| . .||||| |.  .. ..|||| |.. | | ||. ||    .   .|..|..  . . .|..        . |. || |.|||..|| ||||.   
CGTPDYIAPEVILGQGTYGKPVDWWSMGIIMYEFLVGCPPFNGDTPEEMIFQNIINHDREIEWPEEGDPNDDDCMSPEAQDLIKKLLQPNPKKRLGANGA

YDIFKHPFW
..| .||| 
DEIKQHPFF
Kinase 95311.m00044.AA TyrKc 111-360 20 1.2e-13 -2.24 SMART 1-280 (280) Show / Hide 
Range on Protein: 111-360
Range on HMM: 1-280/280
Sequence Identity: 20% (59 aa)

FEFIKEIGKGGSATVYVARNRITNELVAIKCIDKANISSDKRKEHIQSERNTLMRA--RHPFIIRLYNAFQTN-------THLFFVLEFAHGGDLQFQLE
 ...|..| |   .|| .. .   . ||.|.. .        .| . .| . ...   .|| |.||| .  .          |. |.|.. .|||.  | 
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLR

RNC--FSEYQKKLYLAEIALAVKSLHSIGIIYRDLKPENILLDAKGHIKLADFGTAREVRPD----CSCTSFCG----TAEF------LAPEVIQGKENQ
..   ..  ..  .   ||     ||| ..| |||   |.|.......| .||| .|..  |     |           . .      .|||.|  ... 
KHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGK

-SFAIDWWSFGVVAY-MFFVGSCPFTS-----PLRTRLFESIVHKPLRFPPKS--------VDPVTQDFISKLLEKNPAKR-----LGSPGYDIF
 ... | |||||. . .|  |  |           ....| . .   . .|..          .   . ...  . .|..|     .    ...|
FTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI----HECF
Kinase 95311.m00044.AA Pkinase_Tyr 111-261 25 2.7e-09 32.13 Pfam 1-164 (270) Show / Hide 
Range on Protein: 111-261
Range on HMM: 1-164/270
Sequence Identity: 25% (42 aa)

FEFIKEIGKGGSATVYVARNR----ITNELVAIKCIDKANISSDK--RKEHIQSERNTLMRA-RHPFIIRLYNAFQ-TNTH--LFFVLEFAHGGDLQFQL
 .|.|..|.|   .|| .. .     |.  ||.|.. | . ...   |.. .. | ....   .|| |.||| .      .  .. |.|.. .|||   |
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

ERN-----CFSEYQKKLYLAEIALAVKSLHSIGIIYRDLKPENILLDAKGHIKLADFGTAREVRPD
 ..      ..  ..  . ..|| .   |.|...| |||   |.|.. ....| .||| || . .|
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYND