Gene 82699.m00122 (T.vaginalis)
82699.m00122
Species: T.vaginalis
Alias: 82699.m00122, TvagK0160
External Links:
Annotation:
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
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82699.m00122.AA | Protein | None | 308 | None | Fasta, JSON |
82699.m00122.kin_dom | Protein Kinase Domain | None | 219 | None | Fasta, JSON |
Protein domains of 82699.m00122.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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S_TKc | 82699.m00122.AA | S_TKc | 14-258 | 26 | 3.9e-61 | 210.35 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 14-258 Range on HMM: 1-231/231 Sequence Identity: 26% (70 aa) YSYTNIISQTSNCEIMKVYSTKYQTFFAMKKILKKNYNNKELEILKSVHHSSIIYLYDFLEFDDYIYMVYEYCPK---SVNDIIASKEH------LSHSQ | ..| . . . .|.. .| . .|.|.| . .|..|||. || |. |||. . |..||| |||. .. |.| .. . .. . YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-H LQHLIFQILTSLKVLHDYSISHGDFKPANILLDANGRVKLSNFDLSTILNEKCPISNNYRGTLLFMAPEIFNKSGYDPIKADIWALGVTLFALVTKEYPF .... ||. |. .|. | | | ||.||||| ..|.. | |...| . . ||. .||||.. ||.. |.|.|..|..|. ... . || ARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPF YAEDQMSLMQLVSKGVFAKYRILDDNLRKLISKCLELNPQSRPTIDDLLN-------SPYF . ... ..... .. .. .|.|||. .|. |||. ..|. |.| P--QMQMMFKKIG----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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Kinase | 82699.m00122.AA | CAMK | 19-258 | 16 | 1.4e-57 | 183.76 | In-house | 1-425 (425) | Show / Hide |
Range on Protein: 19-258 Range on HMM: 1-425/425 Sequence Identity: 16% (72 aa) IISQTSNCEIMKVYSTKYQ------------TFFAMKKILKKNYNN---------------------------------KELEILKS-------VHHSSI .. . | .. ... .. . . .|.| | || . .|.||.|. ..| | TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI IYLYDFLEF-------------------DDYIYMVY---EYCPK-----SVNDIIASKEH---------------LSHSQLQHLIFQILTSLKVLHDYSI | ||.. | |...||| |||. . | | .... .. .. .... ||. .. .|. | IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI SHGDFKPANILLDAN-----------------GRVKLSNFDLSTILNEKC-----------------------PISNNYRGTLLFMA-PEIFNK------ | | || ||||| | . .|.. | ........ . . . ||. .|| ||..|. VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM -------SGYDPIKADIWALGVTLFALVTKEYPFYAE-------------DQMSLMQLVSKGVF--AKYRILD----------------------DNLRK |.. |.|.|..|| |..... ..|||.. .. |.. . || . . . . . . QNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKD LISKCLELNPQSRPTIDDLLNSPYF ||.|.|. .|. |.||.. || | . LIRKMLQVDPEKRMTIEQCLNHPWM |
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Kinase | 82699.m00122.AA | Pkinase | 40-258 | 26 | 4.9e-54 | 190.63 | Pfam | 27-293 (293) | Show / Hide |
Range on Protein: 40-258 Range on HMM: 27-293/293 Sequence Identity: 26% (70 aa) FAMKKILKKNYNN---------KELEILKSVHHSSIIYLYDFLEFDDYIYMVYEYCPK-----SVNDIIA--SKEHL--SHSQLQHLIFQILTSLKVLHD .|.|.| |.. . |..|.|...| |. |||. | .|.|||| |||.. . |.| .. . | .... . ||| |. .|. VAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHS YSISHGDFKPANILLDANGRV----KLSNFDLSTIL-NEKCPISNNYRGTLLFMAPEIFNKSGYDPIKADIWALGVTLFALVTKEYPFYAE------DQM .| | | ||.|||.| || . |.. | |. . . . . . . ||. .||||. ... |.. |.|.|..|..|. ..... ||. . ||| MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQM SLMQLVSKGVFAKYRILD---------------------DNLRKLISKCLELNPQSRPTIDDLLNSPYF ..... .. . . . ......|..||...|..|||....|..|.| QMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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Kinase | 82699.m00122.AA | CAMKL | 41-258 | 27 | 1.8e-52 | 165.72 | In-house | 29-297 (297) | Show / Hide |
Range on Protein: 41-258 Range on HMM: 29-297/297 Sequence Identity: 27% (75 aa) AMKKILKKNYNN--------------------KELEILKSVH---HSSIIYLYDFLEFDDY------IYMVYEYCPKS---VNDIIASKEH----LSHSQ |.| | || .| .| .|.|... | || ||. .| ... ||.| |||. | | ...| .. .. AIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVMEYCSGGEMDLFDYIVKHGHRRGRMPEHE LQHLIFQILTSLKVLHDYSISHGDFKPANILLDANG--RVKLSNFDLSTILNE----KCPISNNYRGTLLFMAPEIFNK--SGYDPIKADIWALGVTLFA ... ||. .. .|. | | | || ||||| || .|.. | .|.. . . . |.. .||||||.. || |.|||..||.|.| ARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYA LVTKEYPFYAED---------QMSLMQLVSKGVFAKYRILDDNLRKLISKCLELNPQSRPTIDDLLNSPYF .|. ..|| ... . ... . . . .. .. .| ||.| |. || ||||....| | . MVCGYLPFDDDTYNKQGKDNIYLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM |
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Kinase | 82699.m00122.AA | Ciliate-E2-Unclassified | 14-258 | 20 | 4.1e-45 | 154.43 | In-house | 1-352 (352) | Show / Hide |
Range on Protein: 14-258 Range on HMM: 1-352/352 Sequence Identity: 20% (74 aa) YSYTNIISQTSNCEIMKVYSTKYQTFF-------AMKKILKKNYNN--------KELE----------------ILKSVHHSSIIYLYDFLEFDDYIYMV | .| | ..... |.. | . .. .... .|...| ||.. ||.. | |..... . ...||.| YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV YEYCP-KSVNDIIASKEH-----------------LSHSQLQ-----HLIFQILTSLKVLHDYS-ISHGDFKPANILLDANG---RVKLSNFDLSTILNE .|||. .. ..| .... .. | . ... ||| |. || | | | || |||.| || ..|.. | .| ... MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ K------------CPISNNY---RGTLLFM----APEIFNKSGYDP---IKADIWALGVTLFALVTKEYPFYAEDQMS----------------LMQLVS ...... ||. .| |||.. . .|| .|.|||.||| |..... .||||.... . | | NNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIK KGVFAKYR--------ILDDNLRKLIS----KCLELNPQSRPTIDDLLNSPYF .. . . ..... .|. |.|. || .|.|....|| |.| QKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF |
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Kinase | 82699.m00122.AA | STE | 37-258 | 23 | 7.4e-45 | 155.34 | In-house | 39-359 (359) | Show / Hide |
Range on Protein: 37-258 Range on HMM: 39-359/359 Sequence Identity: 23% (76 aa) QTFFAMKKILKKNYNN----------------------KELEILKSVH--HSSIIYLYDFLEFD-------DYIYMVYEYCP-KSVNDIIASK------- ....|.|.. ..| || ||..|.| . | |. |. . . |..... ||.. |. ||| .| GEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYFKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPL -------EHLSHSQLQHLIFQILTS-LKVLHDYSISHGDFKPANILLDANGRVKLSNFDLSTILNEKCP----------------ISNNYRGTLLFMAPE ... ||. . ..||| |. ||. | | | ||||||| |||..| ....|..... .| || .|||| NHNRQHQHRFPESQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPE IFNK------SGYDPIKADIWALGVTLFALVTKEYPFYAEDQMSLMQLVSKGV-------------FAKYRILD----------------------DNLR . .. .||| .|.||| || |. ..| ..|. . |. | . .. . .. | .... VIQQNGQGRDKGYD-TKCDIWSLGCTIIEMATGKPPWHDMHPMRAMFMIPFNYHMQQQFEQLCIVNGPPPPLPDHLSQNEMISYGGSGTTYPHKWSPEFK KLISKCLELNPQSRPTIDDLLN--SPYF |.|||. .|. ||| ..||. | . DFINKCLQKDPNKRPTASQLLKSEHPFI |
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Kinase | 82699.m00122.AA | Ciliate-E2 | 14-258 | 19 | 5.4e-44 | 148.91 | In-house | 1-365 (365) | Show / Hide |
Range on Protein: 14-258 Range on HMM: 1-365/365 Sequence Identity: 19% (75 aa) YSYTNIISQTSNCEIMKV--YSTKYQT---------------------FFAMKKILKK--NYNNKELEILK----------------SVHHSSIIYLYDF | ..| | . . |. .....| ..||| . |. .. ..|. |.. .. | || .|.. YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC LE--FDDYIYMVYEYCPK-SVNDIIASKEHLS-----------HSQLQHLIFQILT---------------SLKVLHDYS-ISHGDFKPANILLDANGRV . |..||.| ||| . |.| .. . . . . .... ||| |. || | | | || |||. . FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I KLSNFDLSTILNE------------KCPISNN--------------------YRGTLLFMAPEIFNKSGYDP--------IKADIWALGVTLFALVTKEY |.. | ||..... ... .| . ||. .|||||.|. .|| |.|||.|||.|. ...... KIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP PFYAEDQMSLMQLVSKGVFA------------------KYRILDDNLRKLISK----CLELNPQSRPT-IDDLLNSPYF || .| .. . .. .... ||.| .|. .|. |.| ....|| |.| PF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF |
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Kinase | 82699.m00122.AA | ULK | 43-258 | 22 | 2.3e-42 | 145.68 | In-house | 39-329 (329) | Show / Hide |
Range on Protein: 43-258 Range on HMM: 39-329/329 Sequence Identity: 22% (66 aa) KKILKKNYN----------NKELEILKSVH--------HSSIIYLYDFLEFD--DYIYMVYEYCPK-SVNDIIASKEH----------LSHSQLQHLIFQ .|. .||.. ..| .|.| . | |. |||..| . ..||...|||. ..| . . || .. .. . | QKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQ ILTSLKVLHDYSISHGDFKPANILLDAN------------GRVKLSNFDLSTILNEK---CPISNNYR------GTLLFMAPEIFN----KSGYDPIKAD || .| ||. | | | ||.|||.. . |..|.. | .. ... . . || |.|||.|.. . |. |.| ILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCD IWALGVTLFALVTKEYPFYAEDQMSLM-----QLVSKG------------VFAKY---RILDDNLRKLISKCLELNPQSRPTIDDLLNSPYF || ||. .. ... ..|||| ... .|. .. | |. .. .... ||...|. .. | ....|.| | | IWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF |
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Kinase | 82699.m00122.AA | ULK | 42-258 | 22 | 5.4e-41 | 142.5 | In-house | 38-324 (324) | Show / Hide |
Range on Protein: 42-258 Range on HMM: 38-324/324 Sequence Identity: 22% (65 aa) MKKILKKNYN----------NKELEILKSVH------HSSIIYLYDFLEFD--DYIYMVYEYCPK-SVNDIIASKEH---------LSHSQLQHLIFQIL .||. ||... ..| .|.| . | |. |||..| . ..||...|||. ..| . . || .. .. . ||. KKKMNKKKNEQEGQYMWQLLKNEIQIMKKLKELKHPNH-HIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETEEKKRLSEQEAIQFFKQIC TSLKVLHDYSISHGDFKPANILLDAN------------GRVKLSNFDLSTILN---EKCPISNNYR------GTLLFMAPEIFN----KSGYDPIKADIW .| ||. | | | ||.|||. . |..|.. | .. ... . . . || |.|||.|.. . |. .|.||| NGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIW ALGVTLFALVTKEYPFYAEDQMSLM----QLVSKG------------VFAKYR---ILDDNLRKLISKCLELNPQSRPTIDDLLNSPYF ||. .. ... .|||.. ... .|. .| | |.. .. .... ||...|. .. | ......| | | SLGCIFYEMLYGKYPFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF |
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Kinase | 82699.m00122.AA | CAMK-Unique | 14-258 | 18 | 9.4e-40 | 128.77 | In-house | 1-363 (363) | Show / Hide |
Range on Protein: 14-258 Range on HMM: 1-363/363 Sequence Identity: 18% (66 aa) YSYTNIISQTSNCEIMKVYSTKYQTFFAMKKILK------KNYN-------------------NKELEILKSVHHSSIIYLYDF----LEFDD------- | .|| . . ... .. . . .|.|.. | |.. .|..|.|.| | || |||. . .. YKMHRIIGHGNFGHVYECMDRETGKKWACKMVKKQTHGNKKQKQQRNFDLRYKITEKRRDMKLKREHQIWKMVDHPNIIKLYDWNNPIFCDRKYPLCDLI --------YIYMVYEYCPKS-VNDIIAS--------------------KEHLSH--SQLQHLIFQILTSLKVLHDYSISHGDFKPANILLDANGR----- |.|.| |||.. ..|.|.. . |.| .. . .....| .. .|. .| |.| |. ||.. .. IKTPRALPYMYIVMEYCQGGDLFDWIQKWDEFYFNFIIKFDFNILKRCQGHFSERCWDTCFIMQCLLSAVAYMHSQDIVHRDLKLENIMVCYSFKDNNHH -----------VKLSNFDLSTILN--EKCPISNNYRGTLLFMAP--------------EIFNKSGYDPIKA----DIWALGVTLFALVTKEYPFYAEDQM .||..|.|.. .| ..|.. .. ||...||| |. | ..|| . |||.|||... . . . ||..|. RDFPYDWSNWHIKLCDFGLCCHYNHNKMCHMMQTMCGTPCYMAPEIVFCKNYQEMTRDEVINMQCYD-QQCSPASDIWSLGVIMYYMLCGCPPFDCECED --------SLMQLVSKGVF-----AKYRI---LDDNLRKLISKCLELNPQSRPTIDDLLNSPYF .. . .|| . .... ... .. .|... | .| .. || .... RDYENHDKEIFECICKGDYCNFDWKMWHGPDYISQEAKDFVKCCMTVDPDHRWSAKELLEHQWI |
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Kinase | 82699.m00122.AA | MARK | 14-258 | 28 | 1.8e-39 | 126.83 | In-house | 1-262 (262) | Show / Hide |
Range on Protein: 14-258 Range on HMM: 1-262/262 Sequence Identity: 28% (76 aa) YSYTNIISQTSNCEIMKVYSTKYQTFFAMKKILKKNYNN--------KELEILKSVHHSSIIYLYDFLE--FDDY-IYMVYEYCP-KSVNDIIASK--EH | | . | .. .. ...... .| | . |.. | |.||.|...| || |.. | ||.. ||.. ... | | .. . YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR LSHSQLQHLIFQILTSLKVLHDYSISHGDFKPANILLDANG--RVKLSNFDLSTILNEKCPISNNYRGTLLFMAPEIFNKSGYDPIKADIWALGVTLFAL |... .. ||. .. .|. .| | | || |||.|.|| .|.. | .|.. .. . | ||. .||||||.| || |.|||.||| |... LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK-LNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLGVVLYFM VTKEYPFYAED--QMSLMQLVSKGVFAKYRILDDNLRKLISKCLELNPQSRPTIDDLLNSPYF |. .|| . . . |.. . .|.. . . . .|.||.. | .|| ||||..... | . VCGYFPFDGDTQDYKELYKKILRGKYDIPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM |
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Kinase | 82699.m00122.AA | CMGC | 14-213 | 15 | 1.3e-30 | 97.05 | In-house | 1-366 (513) | Show / Hide |
Range on Protein: 14-213 Range on HMM: 1-366/513 Sequence Identity: 15% (59 aa) YSYTNIISQTSNCEIMKVYS--------------TKYQTFFAMKKIL-KKNYNN----------------KELEILKSV-----------------HHSS | . | . . . | . .... . |.||| .. | . |..||| . || YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN IIYLYDFLEFDD-----------------YIYMVYEYCPKSVNDIIASKE---------HLSHSQ------------LQHLI------FQILTSLK--VL |. |||.. ... ..|.| ||.... ..| .. .||. . .... .|||..|| . IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC HDYS--ISHGDFKPANILLDAN--------------------GRVKLSNFDLSTILNEK---------------------CPISNNYRGTLLFMAPEIFN | | | | ||.|||.. | ||.|. | |...... .| |. |||| HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL KSG----------YDPIKADIWALGVTLFALVTK-------EYPFYA---------------EDQMSLM .. |.. . |.|..| .. ..|. .|. ||. .. GWKHYTNHNYSMHYTT-PIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKI |
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Kinase | 82699.m00122.AA | CMGC | 220-258 | 24 | 3.6e-11 | 32.01 | In-house | 459-513 (513) | Show / Hide |
Range on Protein: 220-258 Range on HMM: 459-513/513 Sequence Identity: 24% (14 aa) VFAKYRI------------------LDDNLRKLISKCLELNPQSRPTIDDLLNSPYF || .. | .|. .. |..|.|...|. |.|... |. ||| VF-NW-IYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQYDPDKRITAEQALQHPYF |
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Kinase | 82699.m00122.AA | TyrKc | 14-258 | 18 | 6.9e-10 | -62.76 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 14-258 Range on HMM: 1-280/280 Sequence Identity: 18% (54 aa) YSYTNIISQTSNCEIMK-VYSTKYQTFFAMKKILKKNYNN---KELEILKSV--HHSSIIYLYDFLEFD-------DYIYMVYEYCPK-SVNDIIASKEH . .. .|..| ... . | |.. . .|..|.... || |. || . . ...| ||.|. . .| . .... ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP -LSHSQLQHLIFQILTSLKVLHDYSISHGDFKPANILLDANGRVKLSNFDLSTILNEK-------CPISN----NYR--GTLLFMAPEIFNKSGYDPIKA |....| . .|| ||. . | | |.|...|..|| | | || . .. .. . . . |||| .|.. . .| KLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT-TKS DIWALGVTLFALVTKEYPFYAE------DQMSLMQLVSKG-VFAKYRI--------LDDNLRKLISKCLELNPQSRPTIDDLLNSPYF |.|. ||... . | . | . . ....| .| . | . .....| . .| .||| .. .| DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF |