Gene 89239.m00004 (T.vaginalis)
89239.m00004
Species: T.vaginalis
Alias: TvagK0935, 89239.m00004
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| 89239.m00004.AA | Protein | None | 171 | None | Fasta, JSON |
| 89239.m00004.kin_dom | Protein Kinase Domain | None | 124 | None | Fasta, JSON |
Protein domains of 89239.m00004.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| Kinase | 89239.m00004.AA | CAMKL | 1-64 | 42 | 5.5e-27 | 83.04 | In-house | 149-223 (297) | Show / Hide |
Range on Protein: 1-64 Range on HMM: 149-223/297 Sequence Identity: 42% (32 aa) AHRDLKPANILFDDDF--NIKICDFGLACI---H----EPISQKYCGNLRYAAPEIKHK--KPYDPYKADVWSFG .|||.|| |||.|.. ||||.|||.. . . . || . |.|||| . |||| .|.|.|| | VHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCG |
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| Kinase | 89239.m00004.AA | CAMK | 1-64 | 28 | 1.1e-26 | 82.35 | In-house | 201-321 (425) | Show / Hide |
Range on Protein: 1-64
Range on HMM: 201-321/425
Sequence Identity: 28% (34 aa)
AHRDLKPANILFDDD-----------------FNIKICDFGLACIHEP--------------------------ISQKYCGNLRYAA-PEIKHK------
.|||||| |||.||. .||||.|||.|.. .| . .|| . |.| ||. .
VHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNM
-------KPYDPYKADVWSFG
|||...|.|.|| |
QNATDEEKPYYGPKCDMWSCG
|
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| Kinase | 89239.m00004.AA | MARK | 1-64 | 53 | 1.6e-23 | 73.88 | In-house | 126-193 (262) | Show / Hide |
Range on Protein: 1-64 Range on HMM: 126-193/262 Sequence Identity: 53% (37 aa) AHRDLKPANILFDDDF--NIKICDFGLACIHEPISQKY---CGNLRYAAPEIKHKKPYDPYKADVWSFG .|||.|| ||| |.. ||||.|||.. |. | || || . |.|||| ||||| .|.|.|| | VHRDIKPENILIDENGNHNIKIIDFGFS-ICIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLG |
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| Kinase | 89239.m00004.AA | ULK | 2-120 | 25 | 3.9e-23 | 77.67 | In-house | 153-323 (329) | Show / Hide |
Range on Protein: 2-120 Range on HMM: 153-323/329 Sequence Identity: 25% (43 aa) HRDLKPANILFDDDFN------------IKICDFGLACI-HEP-------ISQK----YCGNLRYAAPEIKH----KKPYDPYKADVWSFGLIVAFMAMG |||.||.||| .... .||.|||.| .. ... .|| | ||.| . .|||. ||.|.||.| | | | HRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYG PDAFAQW-TEYL-----EY-------------GSCIFPKE-----IPQNLVNIIRHCIFLNPEQRWSMAEI | | ... . ||| | ... ..|| .. ....| | |. KPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGNDPQISPECKDLIRRMLQYDEKDRISWEEL |
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| Kinase | 89239.m00004.AA | ULK | 2-120 | 26 | 4.6e-22 | 75.13 | In-house | 149-318 (324) | Show / Hide |
Range on Protein: 2-120 Range on HMM: 149-318/324 Sequence Identity: 26% (45 aa) HRDLKPANILFDDDFN------------IKICDFGLACIHEP--ISQKYC----------GNLRYAAPEIKH----KKPYDPYKADVWSFGLIVAFMAMG |||.||.||| ... .||.|||.| . . .| | | | ||.| . .|||. ||.|.||.| | | | HRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYG PDAFAQW-TEYL----------------EYGSCI-FP---KEIP--QNLVNIIRHCIFLNPEQRWSMAEI | | ... .. | || |... ... ..|| .. ....| | || KYPFFSWFNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEI |
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| Kinase | 89239.m00004.AA | Pkinase | 2-68 | 42 | 8.5e-22 | 78.15 | Pfam | 131-203 (293) | Show / Hide |
Range on Protein: 2-68 Range on HMM: 131-203/293 Sequence Identity: 42% (32 aa) HRDLKPANILFDDDFNI----KICDFGLAC---IHEPISQKYCGNLRYAAPEIKHK-KPYDPYKADVWSFGLIVA ||||||.|||.|.. .| ||||||||. .. . . .|| ..|.|||. .. .|...|.|.||.|.|.. HRDLKPENILIDNNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEV-IRGGQYYGPKVDMWSCGCILY |
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| Kinase | 89239.m00004.AA | Ciliate-E2-Unclassified | 2-73 | 33 | 3.3e-21 | 70.32 | In-house | 167-266 (352) | Show / Hide |
Range on Protein: 2-73 Range on HMM: 167-266/352 Sequence Identity: 33% (33 aa) HRDLKPANILFDDD---FNIKICDFGLA------------------CIHEPISQKYCGNLRYA----APEIKHKKPYDP---YKADVWSFGLIVAFMAMG |||.|| |||||.. ..|||.|||.. . . ... ||...| |||. .. || ||.|.||.| | .| .| HRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFG |
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| Kinase | 89239.m00004.AA | TKL | 1-124 | 19 | 2.5e-20 | 69.93 | In-house | 162-364 (364) | Show / Hide |
Range on Protein: 1-124
Range on HMM: 162-364/364
Sequence Identity: 19% (39 aa)
AHRDLKPANILFDDDFN--------------IKICDFGLACIHEPISQKY----------------------CGNLRYAAPEIKHKKPYDP---------
.|||||..||| |.... .|||||||. ... ... ||..|. |||. ......
IHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFC
------YKADVWSFGLIVAFMAMGPDAFA-QWTEYLE---------YGSC------IFP------------KEIPQNLVNIIRHCIFLNPEQRWSMAEIV
|.||.|||.. .. . .. .. . . .. | | . .|. . ... .| .||.| |. ||.
KGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEIL
RYL
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KRL
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| Kinase | 89239.m00004.AA | PLK-Unclassified | 2-67 | 46 | 1.2e-16 | 58.37 | In-house | 129-198 (264) | Show / Hide |
Range on Protein: 2-67 Range on HMM: 129-198/264 Sequence Identity: 46% (33 aa) HRDLKPANILFDDDFNIKICDFGLACIHEP-ISQKY--CGNLRYAAPEIKHKKP--YDPYKADVWSFGLIV |||||..||...|. ..|||||||| | . |. || | |||| .|. .. |. |.|||| |. HRDLKLGNIFLNDNMEVKICDFGLATKLENDGEKKKTICGTPNYIAPEILDGKHQGHS-YEVDCWSFGCIL |
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| Kinase | 89239.m00004.AA | MLK | 2-66 | 35 | 1.9e-16 | 53.7 | In-house | 150-225 (291) | Show / Hide |
Range on Protein: 2-66 Range on HMM: 150-225/291 Sequence Identity: 35% (27 aa) HRDLKPANILFDD------DFNIKICDFGLAC-IHEPISQ---KYCGNLRYAAPEIKHKKPYDPY--KADVWSFGLI |||||. ||| |. . . ||||||... .|. . . .|.... |||. ... ..| |.||||.|.. HRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVV |
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| Kinase | 89239.m00004.AA | TKL-Unique | 1-67 | 36 | 3e-14 | 46.81 | In-house | 134-218 (290) | Show / Hide |
Range on Protein: 1-67 Range on HMM: 134-218/290 Sequence Identity: 36% (31 aa) AHRDLKPANILFDDD-----FNIKICDFGLACIHE-----PIS-------QKYCGNLRYAAPEIKHK--KPYDPYKADVWSFGLIV .|||||. |.| | . .|||||||||. . ... | ||..|..|||. . |. |.||.||| .. IHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYS-EKSDVYSFGIVL |
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| Kinase | 89239.m00004.AA | S_TKc | 1-124 | 18 | 2e-06 | -81.76 | SMART | 18-231 (231) | Show / Hide |
Range on Protein: 1-124 Range on HMM: 18-231/231 Sequence Identity: 18% (42 aa) A--------------------------------------------------------------------------------------------------H . | CRHKKTGRIVAIKIIKEHIRREIQILKKHHPNIVKLYDVFQDDHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPEHARFYMYQICCALEYCHSHGIIH RDLKPANILFDDDFNIKICDFGLACIHEPISQKYCGNLRYAAPEIKHKKPYDPYKADVWSFGLIVAFMAMGPDAFAQWTEYLEYGSCIFPKEIPQNLVNI |||||.|||.|. .|||||||||.. .|| . | |||. .|.. |.|.||.| |.. |. | | .... . . .. . .. RDLKPENILLDE--HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----SPEAKDF IRHCIFLNPEQRWSMAEIVR---------YL ||.| .||.|.. |. . .. IRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
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| Kinase | 89239.m00004.AA | TKL-Unique | 92-124 | 33 | 1.2e-05 | 16.12 | In-house | 258-290 (290) | Show / Hide |
Range on Protein: 92-124 Range on HMM: 258-290/290 Sequence Identity: 33% (11 aa) PKEIPQNLVNIIRHCIFLNPEQRWSMAEIVRYL | ..|... ..|. | . .|.|| | ||. .| PNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL |
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| Kinase | 89239.m00004.AA | MLK | 92-124 | 27 | 4.4e-05 | 13.72 | In-house | 259-291 (291) | Show / Hide |
Range on Protein: 92-124 Range on HMM: 259-291/291 Sequence Identity: 27% (9 aa) PKEIPQNLVNIIRHCIFLNPEQRWSMAEIVRYL |...| . . . | .|..| |...|| .| PSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL |
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| Kinase | 89239.m00004.AA | PLK-Unclassified | 92-126 | 28 | 0.000787 | 10.59 | In-house | 230-264 (264) | Show / Hide |
Range on Protein: 92-126 Range on HMM: 230-264/264 Sequence Identity: 28% (10 aa) PKEIPQNLVNIIRHCIFLNPEQRWSMAEIVRYLHS |. |. |....|.| . .||.|| .. .| . PCHISDNAKDLIQHILNWNPDQRPTIDQIMMHPFY |
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| Kinase | 89239.m00004.AA | Pkinase_Tyr | 2-26 | 56 | 0.007976 | 10.19 | Pfam | 134-158 (270) | Show / Hide |
Range on Protein: 2-26 Range on HMM: 134-158/270 Sequence Identity: 56% (14 aa) HRDLKPANILFDDDFNIKICDFGLA |||| |.| .... .|||||||| HRDLAARNCLVTENNVVKICDFGLA |
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| Kinase | 89239.m00004.AA | Pkinase_Tyr | 96-124 | 27 | 0.198789 | 5.46 | Pfam | 242-270 (270) | Show / Hide |
Range on Protein: 96-124 Range on HMM: 242-270/270 Sequence Identity: 27% (8 aa) PQNLVNIIRHCIFLNPEQRWSMAEIVRYL |. . .....| .||.| ...||.. | PDEIYDLMKQCWHYDPEDRPTFSEIHEQL |
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| Kinase | 89239.m00004.AA | Pkinase | 91-124 | 16 | 2.114878 | 2.5 | Pfam | 259-293 (293) | Show / Hide |
Range on Protein: 91-124 Range on HMM: 259-293/293 Sequence Identity: 16% (6 aa) FPKEIPQNLVNIIRHCIFLNPEQRWSMAEIVRY--L | ....... .|. |. ..|..|.. ..|. . F-HNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF |
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