TVAG_035090

Species: T.vaginalis
Alias: TvagK1034, TVAG_035090
External Links:
Annotation:

Classification

Group: Atypical
Family: TAF1

Sequence

Name Sequence Type Origin Length Description Download
TVAG_035090.AA Protein None 1230 None Fasta, JSON

Protein domain

Protein domains of TVAG_035090.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
DUF3591 TVAG_035090.AA DUF3591 333-787 33 1.6e-216 730.37 Pfam 1-494 (494) Show / Hide
Range on Protein: 333-787
Range on HMM: 1-494/494
Sequence Identity: 33% (165 aa)

WNSISFHSEKYYTRLKVAKENRMHQ-----AVQHSDPALNLVLI----EPNLRDLENFHHPHVNTLPILGITYTVTW-----------KPDEIPDDDPDA
.| | |....||..|| ...|...|     ...||.|||.|...    ..| |....||.||... .   ...| .|           |.|.........
FNII-FSNDEYYDMLKENHQNKVRQTIGNLNIEHSMPALRLQWPYYKVKLNKREARSFHRPHFQFYI---RPGTQIWVRFSKLKHRKRKHDKREKERMGK

QISPFLK--DLDDLSGRR-GGIIVVEHTVEYPQFITNVGMASTLVTFWHKAHAND-NPRTFD--QHIQILDPDHASPF--IGEIPKNEPVQCLSCNMFNV
.||...|  . .||.... . .|..|.. |||....|.||.|.......|.|..| .....|  .....|.|...|||  .|.....|.|..|..||...
DISEVFKMRTTKDLTLGDNSPVILMEYCEEYPPVMSNFGMGSKIINYYRKKHMEDTHRPKLDDIGETHVLHPQDKSPFWNFGHVHPGEIVPTLYNNMYRA

PVAKHPVESTDFLLVRSLD----EPVFYLRNIDACYCAGLLEARTKVMRPGTKDAQKFNLNFIKAILINIFRGTKQYPGRHHIQVQNVIKEFFPDVNEPK
|..||..|.||||..|| .    .. .||||||...|.|.......|..| ........ |..|.|....|.|  |...||.|......|.||||.||..
PIFKHKPEPTDFLCIRSTTPGGHGQKYYLRNIDHMFCVGQTFPVMEVPGPHSRKVTNMSKNRLKMIVYRLFWG--QKSPRHRISIHDITKHFFPDQNEMQ

LRNILKDFADFYREQG---NGFWRIKEKINLDAEFQKID--ITPEDVCSYQSMLVGHYHLKKSGVNILIRSKRVYQQIQKLEGELTKKVAARIEIELMKT
.|..||.|....|..|   .|.|..||...|..||..|.  |||||.|.|.|| ||..||...|.|.....||.|||||....|.||||...|..|.|..
NRQRLKEFMKYQRDGGMDNQGWWKLKEGETLPDEFEEIRKMITPEDCCLYESMQVGQQHLEDAGYNNTDEFKRDYQQIQEDDDEETKKVQMKIDLEQMMA

PWARTENFVKAFEGQA-MQIQ------RTEDGQQIMRSKSRREHD-NSAGAPQPAPKKPLAGTKADLRALTLRELRDKLVSLGVPTGEIERLSRWNQVAL
||..|.||..|..|.| .|..      ....|....|.||..... ...  ||..|||..|||.|..|........... . |||. ||.|...|....|
PWNTTRNFINATQGKAMLQLHGEGDPTGCGEGFSFIRTKSMKGGFLKQGEGPQDKPKKAVAGTRAKERGGHSYNVAQQQRLYGVPEEEIRRIWYWQKRSL





Bromodomain TVAG_035090.AA Bromodomain 1117-1201 28 1.4e-30 102.16 Pfam 1-89 (89) Show / Hide
Range on Protein: 1117-1201
Range on HMM: 1-89/89
Sequence Identity: 28% (26 aa)

LREVVN--KLKGDGRWEIFYYPV--SKKEVPDYHKIIKTPMCLQDIERNVKNEVYT-TVDKFYQEMSQIRINCKTYNEDRNPDLYRYGEL
......  ... ....|.| .||  ...|.|||..|||.||.|. |....|| .|. ... |. .| ....||.|||. .....|.. ..
CDQIMDMKYIMEHPICEPFWHPVDPDRDEYPDYYDIIKHPMDLSTIQQKLKNNKYRNNIAEFWHDMELMWHNCMTYNG-PDSPIYKDARK

BROMO TVAG_035090.AA BROMO 1106-1215 29 2.2e-29 104.86 SMART 1-118 (118) Show / Hide
Range on Protein: 1106-1215
Range on HMM: 1-118/118
Sequence Identity: 29% (35 aa)

SKSPVTRFNELLREVVNKLKGDG--------RWEIFYYPVSKKE--VPDYHKIIKTPMCLQDIERNVKNEVYTTVDKFYQEMSQIRINCKTYNEDRNPDL
..   . ..|||.||..... .|          ..|. ||..||  .|||..|||.||.|..|.....|  |.... |.. . ..  ||.|||| .. . 
DPK-QKKCQELLKEVMCHKHDHGDPMNRGRPYAWPFMQPVDRKELNYPDYYDIIKNPMDLKTIKKKLENHQYQSMEEFVDDFMLMFNNCMTYNE-PDSEV

YRYGELFWETFLEYLRENRE
|....  ...|.| .|| ..
YKMAKKLQKFFEEKWREFPP