Gene LmjF31.1830 (L.major)

LmjF31.1830

Species: L.major
Alias: LmjF31.1830, LmajK209
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF31.1830.AA Protein None 1369 None Fasta, JSON
LmjF31.1830.kin_dom Protein Kinase Domain None 296 None Fasta, JSON

Protein domain

Protein domains of LmjF31.1830.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
HAMP LmjF31.1830.AA HAMP 429-503 20 1.9e-05 23.17 Pfam 1-78 (78) Show / Hide 
Range on Protein: 429-503
Range on HMM: 1-78/78
Sequence Identity: 20% (16 aa)

NGITVAAVLIFTLIFWRLIHRTISQPLNGVRTSMLASVEHG--DRQLYYPRDS---KLVRFTEVDALIQAHNKTMQQLRD
 .......|...||.. .. |.|..||. ....| .   .|  |...  .. .     ..  |...|..| |  ...||.
LIWVMLIALLIALILAWWLARRITRPLRRLTQAMQRIA-DGDLDVRIE-YGRDRIRPVPGPDEIGQLARAFNQMRDRLRE
S_TKc LmjF31.1830.AA S_TKc 1056-1351 15 5.5e-11 -15.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 1056-1351
Range on HMM: 1-231/231
Sequence Identity: 15% (50 aa)

RRVLALGSAGALCSVNYLIYREV--HPVVAKVIRNAPPGPMSDALRSATPVCAPSSRQAAAVRRLIEKHQQLSHPNLLSFLGFSESLEGGVMPLWEFSPG
 ..| .   ||  .| |. .     . |  |.|.                           .|| |. ...  |||.  .... ..  . .    |. .|
YEILRKIGKGAFGKV-YKCRHKKTGRIVAIKIIK-------------------------EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDG

--GTLRELIFRYPN------VKPVTINRFGLQILTALSYLHERGVAHGSVRLDNVLVSADGKCRLT--GHSGDNEAARELFYMHQTCFISP------LMA
  |.|...| ...         . .. ..  ||. || |.|..|. |  .  .|.|..      ..  | .              |.  .|      .. 
DLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL-

TGALPTP-QCDMFCIGLGALEALTKQPAWKWATGNDGQPLGTAAELSELMKAGGTTFSSALTQGRVVVNVDPLRGASVVGKYSNRAVESLIRCLSLDPAE
     ..  ||.  .|    | |. .| .               .. ...|  |                            |  | . . .||  ||..
---GYGKCKCDWWSCGCILYEMLCGYPPFP--------------QMQMMFKKIG----------------------------SPEAKDFIRKCLQKDPEK

RPTAMQVRE-----ASKEML
|||| .. .     .. . .
RPTA-EALQDEWDIKCHPWF
Kinase LmjF31.1830.AA TKL 1125-1211 19 2e-10 33.79 In-house 82-196 (364) Show / Hide 
Range on Protein: 1125-1211
Range on HMM: 82-196/364
Sequence Identity: 19% (24 aa)

LSHPNLLSFLGFSESLEGG------------VMPLWEFSPGGT-LRELIFRYPNVKPVTINRFGLQILTALSYLHE--------RGVAHGSVRLDNVLVS
|.|||...|.|.. . ..|             .   |. |||. |  |.       .  . |. |.|  ...|||         ....|     .|.|| 
LRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVD

ADGK--------------CRLT
 ...              | ..
ENWTNVSNYMYNPNADWCCKIC
Kinase LmjF31.1830.AA ASK 1119-1202 37 2.5e-09 27.0 In-house 42-127 (254) Show / Hide 
Range on Protein: 1119-1202
Range on HMM: 42-127/254
Sequence Identity: 37% (33 aa)

IEKHQQLSHPNLLSFLGFSESLEGGVMPLWEFSPGGTLRELI-FRYPNVK--PVTINRFGLQILTALSYLHERGVAHGSVRLDNVLV
|. |.|| | |.  .|| . | .| .    |  ||| | .|.  ..  .|    |.| .. |||  |.||||. . |  .. |||||
IALHKQLRHRNIVQYLG-CCSENGYFKIFMEQVPGGSLSALLRSKWGPMKDNENTMNFYTKQILEGLKYLHENQIVHRDIKGDNVLV
Kinase LmjF31.1830.AA TK-Unique 1127-1212 21 3.6e-09 27.91 In-house 63-176 (294) Show / Hide 
Range on Protein: 1127-1212
Range on HMM: 63-176/294
Sequence Identity: 21% (24 aa)

HPNLLSFLGFSESLEGGVMPLWEFSPGGTLRE-LIFRYPN-------------------------VKPVTINRFGLQILTALSYLHE--RGVAHGSVRLD
|||....|| . . .. .| ..|. |.|.|.  | ...|.                         ..| .  .|. ||  ...||..  ... |. .   
HPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRPAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCAR

NVLVSADGKCRLTG
|||.. |..| ...
NVLLTEDKVCKICD
Kinase LmjF31.1830.AA UTK 1123-1212 21 7.3e-09 26.46 In-house 64-168 (296) Show / Hide 
Range on Protein: 1123-1212
Range on HMM: 64-168/296
Sequence Identity: 21% (23 aa)

QQLS-HPNLLSFLGFSESLEGGVMPLWEFSPGGTLRELIFRYPN--------VKPVTINRFGLQILTALSYLHERGVAHGSVRLDNVLVSADG-------
.|.. |||.| ..|   . |.. | ..|. ..| || .  | .         ..  .   . ..|  ...|||..|. |. .   |.|| ...       
KQFHWHPNVLRLVGVC-TQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMM

KCRLTG
.|.. .
VCKIAD
Kinase LmjF31.1830.AA TBCK 1170-1212 25 3.7e-08 25.23 In-house 81-127 (346) Show / Hide 
Range on Protein: 1170-1212
Range on HMM: 81-127/346
Sequence Identity: 25% (12 aa)

TINRFGLQILTALSYLHERGVAHGSVRLDNVLVSADG----KCRLTG
.|...  ||| .|||.| ..  |... ..| . . .|    .  |..
QILCIYYQILCGLSYMHKHHIVHRFLHPHNIYLDDNGNQKLHVKLAN
Kinase LmjF31.1830.AA Pkinase 1122-1192 23 3.9e-08 29.85 Pfam 54-131 (293) Show / Hide 
Range on Protein: 1122-1192
Range on HMM: 54-131/293
Sequence Identity: 23% (19 aa)

HQQLSHPNLLSFLGFSESLEGGVMP-LWEFSPGG----TLRELIF--RYPNV--KPVTINRFGLQILTALSYLHERGVAH
.. |.||| . .... |.  .. .    |. .||     | ..|   |. ..   . .. .. .||| .| |.|..|. |
MKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDYISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIH
Kinase LmjF31.1830.AA Iota 1178-1211 47 1.2e-07 21.11 In-house 109-142 (271) Show / Hide 
Range on Protein: 1178-1211
Range on HMM: 109-142/271
Sequence Identity: 47% (16 aa)

ILTALSYLHERGVAHGSVRLDNVLVSADGKCRLT
|  || .|||||.    ..|||||. ..|  .||
ICLALNFLHERGIIYRDLKLDNVLLDHEGHIKLT
Kinase LmjF31.1830.AA TK 1121-1211 10 1.3e-07 20.74 In-house 96-293 (486) Show / Hide 
Range on Protein: 1121-1211
Range on HMM: 96-293/486
Sequence Identity: 10% (21 aa)

KHQQLSHPNLLSFLG-FSESLE----------GGVMPLWEFSPGGT----LRELIFRYPN----------------------------------------
.|. . |||.....|  ... .          . .| . |. |.|     ||.   . ..                                        
CHSLGHHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCP

------------------------------------VKPVTINRFGLQILTALSYLHER------GVAHGSVRLDNVLVSADGK-----------CRLT
                                    . . .   . .||  ...|||..      .. |. .   |.||. ...           |...
EEQDYDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIA
Kinase LmjF31.1830.AA STE11 1119-1192 27 1.8e-07 23.42 In-house 61-139 (303) Show / Hide 
Range on Protein: 1119-1192
Range on HMM: 61-139/303
Sequence Identity: 27% (22 aa)

IEKHQQLSHPNLLSFLGFSES--LEGGVMPLWEFSPGGTLRELIF-RY-P-NVKPVTINRFGLQILTALSYLHERGVAH
|. ...|.|.|.  ..|.. .   ...|    |. |||.|....  .. | .    .| ..  ||| .|.|||. |. |
IKLMKHLNHKNIVRYYGCCLHDNQNDHVNIFMEYCPGGSLSSMLRHKWGPMKFDEMVIRKYTKQILEGLQYLHSHGIIH
Kinase LmjF31.1830.AA Ciliate-E8 1176-1214 34 2.1e-07 19.19 In-house 96-138 (138) Show / Hide 
Range on Protein: 1176-1214
Range on HMM: 96-138/138
Sequence Identity: 34% (15 aa)

LQILTALSYLHERGVAHGSVRLDNVLVSA--DGKCRLT--GHS
.||. |..|||   ..|    |.|.||    | | ..   | |
QQIMDAFCYLHNNNIIHCDFKLNNILVQRNDDTKIKIIDFGFS
Kinase LmjF31.1830.AA Ciliate-C3 1177-1213 32 2.1e-07 22.9 In-house 104-140 (140) Show / Hide 
Range on Protein: 1177-1213
Range on HMM: 104-140/140
Sequence Identity: 32% (12 aa)

QILTALSYLHERGVAHGSVRLDNVLVSADGKCRLTGH
||| |. ||||  . || ... |.|. . .. ..   
QILQAIDYLHEHNIVHGDIKFSNILINSKDEIKIIDF
TyrKc LmjF31.1830.AA TyrKc 1059-1351 12 4.3e-05 -140.34 SMART 1-280 (280) Show / Hide 
Range on Protein: 1059-1351
Range on HMM: 1-280/280
Sequence Identity: 12% (43 aa)

LALGS---AGALCSVNYLIYREVHPVVAKVIRNAPPGPMSDALRSATPVCAPSSRQAAAVRRLIEKHQQL--SHPNLLSFLGFSESLE------GGVMPL
. ||     || . |   ...   .|  |....                        .. .| ..   .|  .|||.. ..|   . .      . .| .
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---------------------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIV

WEFSPGGTLRELIFRYPN-VKPVTINRFGLQILTALSYLHERGVAHGSVRLDNVLVSADGKC--------RLTGHS----------------GDN-----
 |. |.| |.. . .. . ... .   | .||    .|||.... |      |.||.... .        |  ..                 | .     
MEYMPHGDLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI

-----EAARELFYMHQT------CFISPLMATGALPTPQ-----CDMFCI--GLGALEALTKQPA----WKWATGNDGQPLGTAAELSELMKAGGTTFSS
     |. ..  . ...        .  ..  |. | |      .. . .   . . . . . |                                    
RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS------------------------------

ALTQGRVVVNVDPLRGASVVGKYSNRAVESLIRCLSLDPAERPTAMQVREASKEML
                 . |.  .        .|   ||..|||  ..    .| .
-----------------F-VCCPDEMYQ-IMKQCWHEDPEDRPTFSEI----HECF
Kinase LmjF31.1830.AA TK 1328-1347 40 0.008967 4.27 In-house 467-486 (486) Show / Hide 
Range on Protein: 1328-1347
Range on HMM: 467-486/486
Sequence Identity: 40% (8 aa)

RCLSLDPAERPTAMQVREAS
.| ..||..|||  |..|. 
QCWHYDPEDRPTFSQLHEQL
Kinase LmjF31.1830.AA STE11 1328-1342 53 0.040213 3.82 In-house 282-296 (303) Show / Hide 
Range on Protein: 1328-1342
Range on HMM: 282-296/303
Sequence Identity: 53% (8 aa)

RCLSLDPAERPTAMQ
.|.  || .||||.|
HCFEHDPKKRPTANQ
Kinase LmjF31.1830.AA UTK 1328-1347 35 0.078112 2.06 In-house 277-296 (296) Show / Hide 
Range on Protein: 1328-1347
Range on HMM: 277-296/296
Sequence Identity: 35% (7 aa)

RCLSLDPAERPTAMQVREAS
||   ||.|||.. ..... 
RCWHYDPQERPDFEDLVQQM
Kinase LmjF31.1830.AA Pkinase 1326-1346 42 0.146474 6.6 Pfam 270-290 (293) Show / Hide 
Range on Protein: 1326-1346
Range on HMM: 270-290/293
Sequence Identity: 42% (9 aa)

LIRCLSLDPAERPTAMQVREA
. .|| .||..||||.|. . 
IKWCLCKDPKKRPTAEQILQH