Gene LmjF07.0690 (L.major)

LmjF07.0690

Species: L.major
Alias: LmjF07.0690, LmajK194
External Links:
Annotation:

Classification

Group: STE
Family: STE11
Subfamily: STE11-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF07.0690.AA Protein None 1688 None Fasta, JSON
LmjF07.0690.kin_dom Protein Kinase Domain None 682 None Fasta, JSON

Protein domain

Protein domains of LmjF07.0690.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF07.0690.AA CAMK 1005-1430 11 1.6e-30 94.99 In-house 267-602 (425) Show / Hide 
Range on Protein: 1005-1430
Range on HMM: 267-602/425
Sequence Identity: 11% (59 aa)

FLGGGACGKVYECLNTETG------------QVLAAKQI------------------VFDAKDRKLRTR-----LKQLELELEVLTLAA----RHHVRWI
 || |. |||..| ...|.            |  |.| |                  ... | .. ...     .|... |.|.. .      . . . |
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VGFFGAEK------------RGHS--------VLMYL---EYCQHG----SLLDYMVEGNS------TDAAVWNASSAPDDATPQPSTASAGRSAGCHFG
. .. .                          . | .   |||. |     |.|| ||  .                                       
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQ--------------------------------

AAGSPPVAAVEVWRRHTESVNEDASYLSTCSPLQGLREVRESHTEAAAALKTNSPKQQRQQAADDGSAAAGHVQRAGAEATEATGHASPQVRRHREESVE
                                                                                                    
----------------------------------------------------------------------------------------------------

DEEYPARRGGGCLSAAAASVSSAASSVALSSSALDMMPLSEALHPQMPSLSIEQAQCFTKQIVDGLCFLHQHNYAHLDVKTANVLVAAVD----------
                                          .  .   .. ..|. . .||.... ..|.|| .|.| |  |.|.   .          
----------------------------------------FDIV-ERGRFTEREARRYFRQICSAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDE

-------ECRLADLGCAMRIQPPPPGSPRQQQQGLAGMDKAVRGGANGDLDDVLSPPRYPVLVDRDAITELRGTALYMA-PEMIRFE------------S
          ..| | | ...|       . ..|   | .              .   ..   . .  ..  ||  ||| ||... .             
IFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGE-M-HN-------------Q---WTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEK

HAIGSPADVWSLGCVVMEMTTGCAPWRH
  .| ..|.||.|..   | .|. |...
PYYGPKCDMWSCGVILYIMLCGYPPFYG
Kinase LmjF07.0690.AA Pkinase 1281-1464 19 3.3e-25 90.2 Pfam 102-268 (293) Show / Hide 
Range on Protein: 1281-1464
Range on HMM: 102-268/293
Sequence Identity: 19% (41 aa)

SL--SIEQAQCFTKQIVDGLCFLHQHNYAHLDVKTANVLVAAVDEC----RLADLGCAMRIQPPPPGSPRQQQQGLAGMDKAVRGGANGDLDDVLSPPRY
..  | ...... .||. || ..|...  | |.| .|.|.   ...    ...| |.|  ..                                      
CFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD--------------------------------------

PVLVDRDAITELRGTALYMAPEMIRFESHAIGSPADVWSLGCVVMEMTTGCAPWRHI----AKDKLRVLYRIGSARDELPLPPLIR--------------
  .      | . ||  ||||| || ..  .|...|.||.||.. || .|  |...       |.. ...||.... . . | ...              
--Y-NNS-MTTFCGTPWYMAPEVIR-GGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWT

--AWAEEARE
  .| ||...
FHNWSEECKD
S_TKc LmjF07.0690.AA S_TKc 1000-1681 8 3.7e-23 84.19 SMART 1-231 (231) Show / Hide 
Range on Protein: 1000-1681
Range on HMM: 1-231/231
Sequence Identity: 8% (61 aa)

MAIGAFLGGGACGKVYECLNTETGQVLAAKQIVFDAKDRKLRTRLKQLELELEVLTLAARHHVRWIVGFFGAEKRGHSVLMYLEYCQHGSLLDYMVEGNS
  |.  .| || |||| | ...||.. | |.|                                                                    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------------------------------------------------------------

TDAAVWNASSAPDDATPQPSTASAGRSAGCHFGAAGSPPVAAVEVWRRHTESVNEDASYLSTCSPLQGLREVRESHTEAAAALKTNSPKQQRQQAADDGS
                                                                                                    
----------------------------------------------------------------------------------------------------

AAAGHVQRAGAEATEATGHASPQVRRHREESVEDEEYPARRGGGCLSAAAASVSSAASSVALSSSALDM--MPLSEALHPQMPS-----LSIEQAQCFTK
                        .  || ..  .     .         . ..   ... .    .|     | . .. . .      ..  .|.....
-----------------------EHIRREIQILKK-----HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMY

QIVDGLCFLHQHNYAHLDVKTANVLVAAVDECRLADLGCAMRIQPPPPGSPRQQQQGLAGMDKAVRGGANGDLDDVLSPPRYPVLVDRDAITELRGTALY
||...| ..|.|.  | |.| .|.|.    .  ..| | | ..                                                | . ||  |
QICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------------------------------------------------TTFCGTPWY

MAPEMIRFESHAIGS-PADVWSLGCVVMEMTTGCAPWRHIAKDKLRVLYRIGSARDELPLPPLIRAWAEEAREWLAQEGLPATADAEKQQDEVAACAMEA
||||..       |  ..|.||.||.. || .|. |..      . .....                                                 
MAPEVL-----GYGKCKCDWWSCGCILYEMLCGYPPFP-----QMQMMFKKIG-----------------------------------------------

GGAAQAPRNPSASKADREVSRVDRDSGVVGGDLDNTVSDALDEPCSQRRRVDHGTYGDDGRCVAESAVDRACQHDPPPSSVGDTSCSGCEVAATPRSSLV
                                                                                                    
----------------------------------------------------------------------------------------------------

LTAKMPASVRTPATSTRGGTSSSSFARAASATTAGLQLGGSNAADEVRLFREQRHVMRLYVALQDFVAACVRVRPEDRSSAAELLR-------HPFL
                                                              . ||.  | .. ||.| .| |.|.       ||..
-----------------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF07.0690.AA STE 1285-1428 21 6.5e-22 74.25 In-house 151-268 (359) Show / Hide 
Range on Protein: 1285-1428
Range on HMM: 151-268/359
Sequence Identity: 21% (36 aa)

EQAQCFTKQIVDG-LCFLHQHNYAHLDVKTANVLVAAVDECRLADLGCAMRIQP------------PPPGSPRQQQQGLAGMDKAVRGGANGDLDDVLSP
.|  ....||. | | .||.|.. | |.| ||.|.     . |.| |.. ....                                              
SQIAYICRQILKGLLYYLHSHHIIHRDIKPANILL-----VKLCDFGVCGQLTDSMANIQSNNIIDC---------------------------------

PRYPVLVDRDAIT----ELRGTALYMAPEMIRFESHA----IGSPADVWSLGCVVMEMTTGCAPW
      .  . .      . ||  .||||.|. ....     .  .|.|||||...|| ||. ||
------I--ETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPW
Kinase LmjF07.0690.AA Ciliate-E2 1082-1428 9 1.1e-20 67.73 In-house 113-296 (365) Show / Hide 
Range on Protein: 1082-1428
Range on HMM: 113-296/365
Sequence Identity: 9% (40 aa)

LEYCQHGSLLDYMV----------EGNSTDAAVWNASSAPDDATPQPSTASAGRSAGCHFGAAGSPPVAAVEVWRRHTESVNEDASYLSTCSPLQGLREV
.||||.|.|.||.           |                                                                           
MEYCQGGDLFDYIKNNKKKRNHEIE---------------------------------------------------------------------------

RESHTEAAAALKTNSPKQQRQQAADDGSAAAGHVQRAGAEATEATGHASPQVRRHREESVEDEEYPARRGGGCLSAAAASVSSAASSVALSSSALDMMPL
                                                                                                    
----------------------------------------------------------------------------------------------------

SEALHPQMPSLSIEQAQCFTKQIVD---------------GLCFLHQHN-YAHLDVKTANVLVAAVDECRLADLGCAMRI--------------------
      .  ........ ..|||..               .| .||. |   | | |  |.|.     . ..|.| . ..                    
----K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKN

----------QPPPPGSPRQQQQGLAGMDKAVRGGANGDLDDVLSPPRYPVLVDRDAITELRGTALYMAPEMIRFES-------HAIGSPADVWSLGCVV
          |                                         .  . .  . ||. |||||... ..       .  .  .|.||||.. 
DTSRTPGYMDQ----------------------------------------IIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVIL

MEMTTGCAPW
 || .|  |.
YEMLFGKPPF
Kinase LmjF07.0690.AA STE 1000-1094 17 5.4e-14 45.92 In-house 1-128 (359) Show / Hide 
Range on Protein: 1000-1094
Range on HMM: 1-128/359
Sequence Identity: 17% (23 aa)

MAIGAFLGGGACGKVYECLNTE---------------TGQVLAAKQIVFDAKD----------RKLRTRLKQLELELEVLTLAARHH-VRWIVGFFGAEK
  .  ..| ||.|.|| ..| .               ||.. | ||. .. ..           . .   .. ... |. ..   .|    || ..|.. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

RG-------HSVLMYLEYCQHGSLLDYM
..       ... ...||.  ||| | .
KEGHNHKNDDELWICMEYMDGGSLDDII
Kinase LmjF07.0690.AA STE11 1388-1452 39 1.8e-13 45.3 In-house 197-263 (303) Show / Hide 
Range on Protein: 1388-1452
Range on HMM: 197-263/303
Sequence Identity: 39% (27 aa)

GTALYMAPEMIRFES---HAIGSPADVWSLGCVVMEMTTGCAPWRHIAKDKLRVLYRIGSA-RDELPLP
||. .||||.|. |    .  | .||.|||||.| || ||  ||  .   .   ...||..     |.|
GTPMWMAPEVIKQEGRDGY--GRKADIWSLGCTVIEMATGKPPWHNYDHNHMAAMFKIGMGHKPHPPIP
Kinase LmjF07.0690.AA STE11-Unclassified 1385-1436 37 3.2e-13 43.25 In-house 191-246 (308) Show / Hide 
Range on Protein: 1385-1436
Range on HMM: 191-246/308
Sequence Identity: 37% (22 aa)

ELRGTAL---YMAPEMIR---FESHAIGSPADVWSLGCVVMEMTTGCAPWRHIAKDKL
...||     .||||.|.    ..|  .  .|.|||||.| || || .||  . .|..
SMQGTPYQPFWMAPEVIKNSTQTGH--CRKSDIWSLGCTVIEMATGKHPWSNCQNDNF
Kinase LmjF07.0690.AA STE11 1000-1090 26 2e-12 41.53 In-house 1-100 (303) Show / Hide 
Range on Protein: 1000-1090
Range on HMM: 1-100/303
Sequence Identity: 26% (27 aa)

MAIGAFLGGGACGKVYECLNTETGQVLAAKQIVFDAKD---RKLRTRLKQ----LELELEVLTLAARHHVRWIVGFFGAEKR---GHSVLMYLEYCQHGS
   |...| || |.|| |.|. ||...| ||| ..  .    ...  ...     ... |.  .   .| . || ..|.. .     .|  ..|||  ||
WQKGEIIGKGAFGTVYKCMNVDTGELMAVKQIEIQNNNQMKEDQEKEYQSHKMHKAIQEEIKLMKHLNHKN-IVRYYGCCLHDNQNDHVNIFMEYCPGGS

L
|
L
Kinase LmjF07.0690.AA MEKK15 1381-1465 37 2.3e-12 41.13 In-house 162-240 (264) Show / Hide 
Range on Protein: 1381-1465
Range on HMM: 162-240/264
Sequence Identity: 37% (32 aa)

DAITELRGTALYMAPEMIRFESHAIGSPADVWSLGCVVMEMTTGCAPWRHIAKDKLRVLYRIGSARDELPLPPLIRAWAEEAREW
| .  .|||  .||||.|    .  |  .|.||.|| | || |.  ||  .  |..  .. ||. ||  |.|.|   ..|.||..
DMLKSMRGTPYWMAPEVIMETGY--GRKSDIWSIGCTVFEMATRKPPWADM--DRMAAMFYIGAHRD--PMPQLPVKFSEDARMF
Kinase LmjF07.0690.AA STE11-Unclassified 1000-1090 29 2.6e-11 36.42 In-house 1-94 (308) Show / Hide 
Range on Protein: 1000-1090
Range on HMM: 1-94/308
Sequence Identity: 29% (29 aa)

MAIGAFLGGGACGKVYECLNTETGQVLAAKQIVF-DAK--DRKLRTR-LKQLELELEVL-TLAARHHVRWIVGFFGAE--KRGHSVLMYLEYCQHGSL
   |.|.|.|. |.|| |.|..||...| |||   | .  . ..    ..... |..|| .|   .    ||   |.|  | . ..  ..||.  ||.
WQKGEFIGKGSFGQVYKCMNCNTGEFMAVKQIEIHDYNSQQEDMQKEMIQSIQKEMKVLKQLNHKN----IVQYYGCEIHKHEDCINIFMEYMPGGSI
Kinase LmjF07.0690.AA MEKK4 1388-1428 51 2.4e-10 31.86 In-house 164-212 (271) Show / Hide 
Range on Protein: 1388-1428
Range on HMM: 164-212/271
Sequence Identity: 51% (25 aa)

GTALYMAPEMI-RFESH-------AIGSPADVWSLGCVVMEMTTGCAPW
||| ||||| . . |.          |  ||.||||||| || ||  ||
GTAAYMAPEVYTYTEKDETTGSYSGHGRAADIWSLGCVVVEMMTGKRPW
Kinase LmjF07.0690.AA MEKK2 1001-1092 34 3.9e-10 32.92 In-house 2-92 (262) Show / Hide 
Range on Protein: 1001-1092
Range on HMM: 2-92/262
Sequence Identity: 34% (32 aa)

AIGAFLGGGACGKVYECLNTETGQVLAAKQIVFDAKDRKLRTRLKQLELELEVLTLAARHHVRWIVGFFGAEKRGH--SVLMYLEYCQHGSLLD
  |  || || |.|| |   .||  ||.||. || ..   |   . || |...  |    | | || ..|  .      . ...||   ||. |
RRGKLLGQGAFGRVYVCYDVDTGRELAVKQVQFDPDNPETRKEVQALECEIQL--LKNLQHER-IVQYYGCLRDNQEKTLSIFMEYMPGGSVKD
Kinase LmjF07.0690.AA MEKK15 1001-1090 33 6.9e-10 32.07 In-house 2-88 (264) Show / Hide 
Range on Protein: 1001-1090
Range on HMM: 2-88/264
Sequence Identity: 33% (30 aa)

AIGAFLGGGACGKVYECLNTETGQVLAAKQIVFDAKDRKLRTRLKQLELELEVLTLAARHHVRWIVGFFGAEKRGHSVLMYLEYCQHGSL
  |  || || | || |  |.|||..| ||.  |  | |.... . . |  ||  | . .|.  ||.. |       | .....   ||.
KKGNILGKGAYGTVY-CGLTNTGQLIAVKQVELDEID-KEKAKQQYRKLQEEVDLLKTLKHKN-IVAYLGVCLEDNVVNIFMQFVPGGSI
Kinase LmjF07.0690.AA PAKA 1654-1681 50 9e-10 30.62 In-house 233-260 (260) Show / Hide 
Range on Protein: 1654-1681
Range on HMM: 233-260/260
Sequence Identity: 50% (14 aa)

LQDFVAACVRVRPEDRSSAAELLRHPFL
..||...|  | ...| || |||.||||
FCDFLDKCLCVDVDRRASAQELLHHPFL
Kinase LmjF07.0690.AA STE 1654-1681 36 1.5e-09 30.01 In-house 330-359 (359) Show / Hide 
Range on Protein: 1654-1681
Range on HMM: 330-359/359
Sequence Identity: 36% (11 aa)

LQDFVAACVRVRPEDRSSAAELLR--HPFL
..||.. | .  |..| .| .||.  |||.
FKDFINKCLQKDPNKRPTASQLLKSEHPFI
Kinase LmjF07.0690.AA STE20 1654-1681 46 2.3e-09 30.68 In-house 261-288 (288) Show / Hide 
Range on Protein: 1654-1681
Range on HMM: 261-288/288
Sequence Identity: 46% (13 aa)

LQDFVAACVRVRPEDRSSAAELLRHPFL
..|||. |  . ||.| .| .||.|||.
FHDFVDKCLQKDPEKRPTASQLLKHPFI
Kinase LmjF07.0690.AA TyrKc 1000-1466 12 6.2e-09 -78.2 SMART 1-280 (280) Show / Hide 
Range on Protein: 1000-1466
Range on HMM: 1-280/280
Sequence Identity: 12% (65 aa)

MAIGAFLGGGACGKVYECLNTETGQVLAAKQIVFDAKDRKLRTRLKQLELELEVLTLAAR--HHVRWIVGFFGAEKRG-------HSVLMYLEYCQHGSL
   |  || || |.||..  .   .  | | .  ||          . ..  |   .     ||   || ..|.   .       . ... .||. ||.|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----------REDFMREARIMCKLGGHHPN-IVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

LDYMVEGNSTDAAVWNASSAPDDATPQPSTASAGRSAGCHFGAAGSPPVAAVEVWRRHTESVNEDASYLSTCSPLQGLREVRESHTEAAAALKTNSPKQQ
.||  .   .                                                                                          
KDYLRKHRPK------------------------------------------------------------------------------------------

RQQAADDGSAAAGHVQRAGAEATEATGHASPQVRRHREESVEDEEYPARRGGGCLSAAAASVSSAASSVALSSSALDMMPLSEALHPQMPSLSIEQAQCF
                                                                                           |. ..   |
-------------------------------------------------------------------------------------------LCMKDLLSF

TKQIVDGLCFLHQHNYAHLDVKTANVLVAAVDECRLADLGCAMRIQPPPPGSPRQQQQG-LAGMDKAVRGGANGDLDDVLS--PPR--YPVLVDRDAITE
  || .|  .||..|. | |  . |.||..   .. .| | .           |    .  .|        ...|  .. .    .   |.         
CWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLS-----------RDIYDDDQQG--------ESKDYYRKKEHKGGKTMLPI---------

LRGTALYMAPEMIRFESHAIGSPA-DVWSLGCVVMEMTTGCA-PWRH-IA--KDKLRVLYRIGSA-RDELPLP------------------------PLI
       |||| |    . . ... |||| | .  |. | .. |.   |   ..  .|. .. .  | . |                          |  
-----RWMAPECI---NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPED

RAWAEEAREWL
|   .| .| .
RPTFSEIHECF
Kinase LmjF07.0690.AA MEKK2 1290-1336 38 1.3e-08 27.31 In-house 108-154 (262) Show / Hide 
Range on Protein: 1290-1336
Range on HMM: 108-154/262
Sequence Identity: 38% (18 aa)

FTKQIVDGLCFLHQHNYAHLDVKTANVLVAAVDECRLADLGCAMRIQ
.|.||..|. .||.|   | |.| ||.|  .    .|.| | . |.|
YTRQILEGMHYLHDHMIVHRDIKGANILRDSSGNVKLGDFGASKRLQ
Kinase LmjF07.0690.AA STE11 1290-1336 47 3.6e-08 25.95 In-house 121-168 (303) Show / Hide 
Range on Protein: 1290-1336
Range on HMM: 121-168/303
Sequence Identity: 47% (23 aa)

FTKQIVDGLCFLHQHNYAHLDVKTANVLVAAVDE-CRLADLGCAMRIQ
.||||  || .||.|.  | |.| ||.|. .    |.||| ||| |..
YTKQILEGLQYLHSHGIIHRDIKGANILLDSDGNVCKLADFGCAKRLA
Kinase LmjF07.0690.AA MEKK15 1290-1335 39 3.8e-08 25.67 In-house 106-151 (264) Show / Hide 
Range on Protein: 1290-1335
Range on HMM: 106-151/264
Sequence Identity: 39% (18 aa)

FTKQIVDGLCFLHQHNYAHLDVKTANVLVAAVDECRLADLGCAMRI
.||||..|  .||. .  | |.| .||.. .    .| | ||| |.
YTKQILQGVQYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRL
Kinase LmjF07.0690.AA STE11-Unclassified 1653-1681 37 4.3e-08 24.84 In-house 280-308 (308) Show / Hide 
Range on Protein: 1653-1681
Range on HMM: 280-308/308
Sequence Identity: 37% (11 aa)

ALQDFVAACVRVRPEDRSSAAELLRHPFL
...||  .| ...|..| .| .|| |||.
ECKDFLRKCFQIDPKKRPTANQLLQHPFI
Kinase LmjF07.0690.AA STE11 1653-1681 37 4.4e-08 25.61 In-house 275-303 (303) Show / Hide 
Range on Protein: 1653-1681
Range on HMM: 275-303/303
Sequence Identity: 37% (11 aa)

ALQDFVAACVRVRPEDRSSAAELLRHPFL
...||.  |    |..| .|..||.|||.
ECRDFLRHCFEHDPKKRPTANQLLQHPFI
Kinase LmjF07.0690.AA MEKK2 1388-1428 51 1.1e-07 24.0 In-house 168-206 (262) Show / Hide 
Range on Protein: 1388-1428
Range on HMM: 168-206/262
Sequence Identity: 51% (21 aa)

GTALYMAPEMIRFESHAIGSPADVWSLGCVVMEMTTGCAPW
||  .|.||.|  |    |  |||||.|| |.|| |   ||
GTPYWMSPEVINGE--GYGRKADVWSIGCTVVEMLTEKPPW
Kinase LmjF07.0690.AA STE20 1006-1092 22 5.7e-07 21.84 In-house 7-97 (288) Show / Hide 
Range on Protein: 1006-1092
Range on HMM: 7-97/288
Sequence Identity: 22% (22 aa)

LGGGACGKVYECLNTETGQV----LAAKQIVFDAKDRKLRTRLKQL-ELELEVLTLAARHHVRWIVGFFGAEKRG----HSVLMYLEYCQHGSLLD
.| |. |||| . ...||..     | |..  . .| .   . ... ... |.. ..  .    || ..|.  ..    ..  .  |||. |||.|
IGQGSYGKVYKAYHKPTGEYCNQRVAIKKMNLEKCDNE---Q-DEWEDIQKEISIMKQCK-HPNIVKYYGSYLKDDTCDDELWIVMEYCGGGSLTD
Kinase LmjF07.0690.AA STE20 1388-1427 37 6.3e-07 21.68 In-house 184-226 (288) Show / Hide 
Range on Protein: 1388-1427
Range on HMM: 184-226/288
Sequence Identity: 37% (16 aa)

GTALYMAPEMIRFES---HAIGSPADVWSLGCVVMEMTTGCAP
||  .||||.|. .    .  .. .|.||||   .|| .|  |
GTPYWMAPEVIQCMEGPDKGYDYKCDIWSLGITAIEMAEGEPP
Kinase LmjF07.0690.AA Pkinase 1000-1098 25 8.3e-07 25.15 Pfam 1-102 (293) Show / Hide 
Range on Protein: 1000-1098
Range on HMM: 1-102/293
Sequence Identity: 25% (27 aa)

MAIGAFLGGGACGKVYECLNTETGQVLAAKQIVFDAKDRKLRTRLKQLEL--ELEVLTLAARHHVRWIVGFFGAEKRGHSVLMYLEYCQHG----SLLDY
  ||  .| |. |.||.| .  ||.. | |.|    |...    .... .  |....    .|    || ....  .. .. | .|||..|    .| ||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIK---KRHEKSWKDQTHRRLSEIQIMKRL-NHPN--IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDY

MV---EGN
.    .|.
ISTWRHGC
Kinase LmjF07.0690.AA STE11-Unclassified 1287-1318 46 2e-06 18.65 In-house 109-140 (308) Show / Hide 
Range on Protein: 1287-1318
Range on HMM: 109-140/308
Sequence Identity: 46% (15 aa)

AQCFTKQIVDGLCFLHQHNYAHLDVKTANVLV
.. .||||  || .||.|.  | |.| ||.|.
IKKYTKQILEGLAYLHSHGIIHRDIKGANILI
Kinase LmjF07.0690.AA STE20 1291-1330 35 3e-06 19.02 In-house 123-162 (288) Show / Hide 
Range on Protein: 1291-1330
Range on HMM: 123-162/288
Sequence Identity: 35% (14 aa)

TKQIVDGLCFLHQHNYAHLDVKTANVLVAAVDECRLADLG
..... || .||.... | |.| .|.|.    |. ||| |
CREVLQGLDYLHSNHIIHRDIKADNILLTEDGEVKLADFG
Kinase LmjF07.0690.AA MEKK15 1655-1681 37 8e-06 17.22 In-house 238-264 (264) Show / Hide 
Range on Protein: 1655-1681
Range on HMM: 238-264/264
Sequence Identity: 37% (10 aa)

QDFVAACVRVRPEDRSSAAELLRHPFL
..|| .|.    ..|..| .||.|||.
RMFVRMCLTRDQHERPTASQLLKHPFI
Kinase LmjF07.0690.AA PAKA 1001-1039 31 9e-06 16.44 In-house 2-42 (260) Show / Hide 
Range on Protein: 1001-1039
Range on HMM: 2-42/260
Sequence Identity: 31% (13 aa)

AIGAFLGGGACGKVYECLNTETGQV--LAAKQIVFDAKDRK
.    .| || |.||.. |..|.|    | ||. ... ..|
KFMEKIGQGASGEVYVATNIKTNQEENVAIKQMNMKNQPKK
Kinase LmjF07.0690.AA MEKK4 1290-1336 36 1.3e-05 15.44 In-house 103-149 (271) Show / Hide 
Range on Protein: 1290-1336
Range on HMM: 103-149/271
Sequence Identity: 36% (17 aa)

FTKQIVDGLCFLHQHNYAHLDVKTANVLVAAVDECRLADLGCAMRIQ
.|||.  .   ||||   | |.|.||.         | | ||. ..|
YTKQLLRAVNYLHQHGIVHRDIKPANIFLDKCTVLKLGDFGCSVKLQ
Kinase LmjF07.0690.AA MEKK4 1001-1033 42 1.4e-05 15.24 In-house 2-34 (271) Show / Hide 
Range on Protein: 1001-1033
Range on HMM: 2-34/271
Sequence Identity: 42% (14 aa)

AIGAFLGGGACGKVYECLNTETGQVLAAKQIVF
. |   | |  |||| | |  |. |.|.| . |
QRGDHIGEGQFGKVYTCMNMDTHEVMAMKEMRF
Kinase LmjF07.0690.AA Pkinase 1653-1681 31 3.1e-05 19.59 Pfam 265-293 (293) Show / Hide 
Range on Protein: 1653-1681
Range on HMM: 265-293/293
Sequence Identity: 31% (9 aa)

ALQDFVAACVRVRPEDRSSAAELLRHPFL
...||.  | .. |..| .|...| ||..
ECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF07.0690.AA CAMK 1655-1681 29 5.1e-05 11.33 In-house 399-425 (425) Show / Hide 
Range on Protein: 1655-1681
Range on HMM: 399-425/425
Sequence Identity: 29% (8 aa)

QDFVAACVRVRPEDRSSAAELLRHPFL
.|..  . .| ||.| .... |.||..
KDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF07.0690.AA MEKK4 1656-1681 46 0.000115 12.11 In-house 246-271 (271) Show / Hide 
Range on Protein: 1656-1681
Range on HMM: 246-271/271
Sequence Identity: 46% (12 aa)

DFVAACVRVRPEDRSSAAELLRHPFL
||   |    | ||  |.||| |.|.
DFFDHCLEHDPKDRWTANELLDHTFC
Kinase LmjF07.0690.AA PAKA 1292-1337 23 0.00014 12.17 In-house 110-155 (260) Show / Hide 
Range on Protein: 1292-1337
Range on HMM: 110-155/260
Sequence Identity: 23% (11 aa)

KQIVDGLCFLHQHNYAHLDVKTANVLVAAVDECRLADLGCAMRIQP
...  || |.|... .| |.|  |.|. .  .  ..| | . ....
RECLQGLEFIHSKHRIHRDIKSDNILLGMDGSVKITDFGFCAQLTQ
Kinase LmjF07.0690.AA MEKK2 1656-1681 50 0.000246 11.62 In-house 237-262 (262) Show / Hide 
Range on Protein: 1656-1681
Range on HMM: 237-262/262
Sequence Identity: 50% (13 aa)

DFVAACVRVRPEDRSSAAELLRHPFL
||.  | .    || ||.||||| | 
DFLKRCFVEIKQDRPSAEELLRHHFV
Kinase LmjF07.0690.AA Pkinase_Tyr 1082-1330 8 0.000299 15.02 Pfam 86-156 (270) Show / Hide 
Range on Protein: 1082-1330
Range on HMM: 86-156/270
Sequence Identity: 8% (21 aa)

LEYCQHGSLLDYMVEGNSTDAAVWNASSAPDDATPQPSTASAGRSAGCHFGAAGSPPVAAVEVWRRHTESVNEDASYLSTCSPLQGLREVRESHTEAAAA
.||..||.||||  .                                                                                     
MEYMPHGDLLDYLRKHR-----------------------------------------------------------------------------------

LKTNSPKQQRQQAADDGSAAAGHVQRAGAEATEATGHASPQVRRHREESVEDEEYPARRGGGCLSAAAASVSSAASSVALSSSALDMMPLSEALHPQMPS
                                                                                               .. ..
-----------------------------------------------------------------------------------------------EDKQP

LSIEQAQCFTKQIVDGLCFLHQHNYAHLDVKTANVLVAAVDECRLADLG
|....  ..  || .|. .|...|. | |. . |.||.    .. .| |
LTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFG
Kinase LmjF07.0690.AA PAKA 1388-1424 43 0.002004 8.06 In-house 165-199 (260) Show / Hide 
Range on Protein: 1388-1424
Range on HMM: 165-199/260
Sequence Identity: 43% (16 aa)

GTALYMAPEMIRFESHAIGSPADVWSLGCVVMEMTTG
||  .|||| ||   .  .   |.||||  ..||  |
GTPYWMAPEVIR--RKQYDEKVDIWSLGIMAIEMIEG
Kinase LmjF07.0690.AA Ciliate-E2 1664-1681 31 0.002992 6.99 In-house 347-365 (365) Show / Hide 
Range on Protein: 1664-1681
Range on HMM: 347-365/365
Sequence Identity: 31% (6 aa)

VRPEDRSS-AAELLRHPFL
. || | . . ..| ||..
KDPEKRITGWEQILNHPWF