Gene LmjF36.4550 (L.major)
LmjF36.4550
Species: L.major
Alias: LmjF36.4550, LmajK163
External Links:
Annotation:
Secondary Group: PKL,
Third Group: PKL,
Secondary Family: Alpha,
Third Family: Alpha,
Secondary Subfamily: Alpha-Kineto1,
Third Subfamily: Alpha-Kineto1
Sequence
Name | Sequence Type | Origin | Length | Description | Download |
---|---|---|---|---|---|
LmjF36.4550.AA | Protein | None | 1141 | None | Fasta, JSON |
LmjF36.4550.kin_dom | Protein Kinase Domain | None | 237 | None | Fasta, JSON |
LmjF36.4550.kin_dom2 | Protein Kinase Domain | None | 240 | None | Fasta, JSON |
LmjF36.4550.kin_dom3 | Protein Kinase Domain | None | 205 | None | Fasta, JSON |
Protein domains of LmjF36.4550.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
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Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
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Alpha_kinase | LmjF36.4550.AA | Alpha_kinase | 164-382 | 22 | 7.9e-51 | 177.16 | Pfam | 1-225 (225) | Show / Hide |
Range on Protein: 164-382 Range on HMM: 1-225/225 Sequence Identity: 22% (55 aa) IHQDKYFATFAVELL--DLVKPATPMLAKVYRH----NID---LVSETDYYSLGQAQALCEEFARDYTRTAARSHYVKFHLPLLTNRVVVRLDMDSVLDP ..| .... | .. . . .. ... ||.|.. |.. .|.| .| . ...|..|....... ... ... .... . .|..|. .. .|. FAQGAMRWCFRMFDTWDPNWRNNQNCVAKWYKKIKNYNQKQSIYVEEDYYFQDCKMQMICQQWMEKFNQKLQEHNNPPPPIEFYDCCIVYELEDHNKPDC AIRTARKGFFSYRTQDTRQVMFLMEPNTVACEALGI-SFASREVDEGKCYSRGDAMWSRDIYRDIADGFSHFTYVRSRMCMVAHGFMRSN--G---YLLD .. ||||||| |.......|||. . . | . |..| |.|. .| . ... ||||||.||. .|. . . . || | YQ-----GFFSYRT-DWGGKYWYMEPY------IEGCEFVKYNNNYGWVY---DNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNKCYYLTD PLFHTTDSER---F--TMGDAGRSAMEDWVE-GHRCGDTC | ||.|... | .||. | ..| ... |.| ..| PQIHTKDGNYEMDFDEGMGNLGQEGIEKFFQNQHKCNHIC |
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Alpha_kinase | LmjF36.4550.AA | Alpha_kinase | 145-382 | 19 | 4.6e-09 | 18.95 | SMART | 1-255 (255) | Show / Hide |
Range on Protein: 145-382 Range on HMM: 1-255/255 Sequence Identity: 19% (52 aa) TRRWLAHHITVRV---LHHNRGIHQDKYFATFAVELLDLVKPATPMLAKVYRHNIDLVS-ETDYYS--------LGQAQALCEEFARDYTRTAARSHYVK . |.. ...|.. .. .| . | . . | ... .. . . ||...... . | .|. ...| .|...|... . |. .. . DNKWTCQETCVKIKEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHETLHLCLRDVEMQMMCKHWANEFNQEAQ-HNPCP FHLPLLTNRVVVRLDMDSVLDPAIRTARKGFFSYRTQDTRQVM----FLMEPNTVACEALG---ISFASREVDEGKCYSRGDAMWSRDIYRD----IADG . . |.... . . . . ....|||||.|.. || |.||| .. . . .. .. | .. | | .. KKIDFIPCYVFHFPRR-IPA--EYDRNIPYWFSYRTTDQMMVMCCCIFHMEPF------MEGEFVKYNNNNGWVNDCMRWTT-T-SQ-R-RTEMFEYCQA FSHFTYVRSRMCMVAH---GFMRSNGY--LL-DPLFHTTD--SERFTMGDAGRSAMEDWVEGHRCGDTC |||.||..|. .|. | ..||. .. || ||.| . | || | ..| ... |.| . | FSHWTYEWSNHQMLVCDIQGVIHKNGDLYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC |
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Kinase | LmjF36.4550.AA | Alpha | 343-382 | 23 | 0.03033 | 2.02 | In-house | 170-215 (215) | Show / Hide |
Range on Protein: 343-382 Range on HMM: 170-215/215 Sequence Identity: 23% (11 aa) NGYLLDPLFHT----TDSERFTMGDAGRSAMEDWVEGH--RCGDTC ...| || |. ...| |. | ..| . | | . | EWKLTDPQIHCPAKLDQGMKFGDGNCGYEGMFRFFYTHHVQCNHYC |
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Kinase | LmjF36.4550.AA | VWL | 343-387 | 30 | 0.130384 | 0.68 | In-house | 161-206 (206) | Show / Hide |
Range on Protein: 343-387 Range on HMM: 161-206/206 Sequence Identity: 30% (14 aa) NGYLLDPLFHTTDS-ERFTMGDAGRSAMEDWVEGHRCGDTCRALGI .| | || |. | ..| |..| . | | | . |. | DGMLTDPQIHCLDQSHKFGQGNLGYEGMLRFFMTHQCNKYCQKLQL |
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Alpha_kinase | LmjF36.4550.AA | Alpha_kinase | 646-713 | 32 | 2.3e-10 | 37.0 | Pfam | 147-225 (225) | Show / Hide |
Range on Protein: 646-713 Range on HMM: 147-225/225 Sequence Identity: 32% (26 aa) LRHVVDAFSHFTLHKSGNHLLVCHFKCQG--G---LLMHPNINTSSGCG---F--ETLNDGQAGIDAWAR-AHTCNDVC . ... |||||| |.|. ..||. | . .| | |.| |.. | . | || ||. . | ||..| WNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNKCYYLTDPQIHTKDGNYEMDFDEGMGNLGQEGIEKFFQNQHKCNHIC |
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Alpha_kinase | LmjF36.4550.AA | Alpha_kinase | 486-713 | 21 | 1.3e-07 | 0.76 | SMART | 1-255 (255) | Show / Hide |
Range on Protein: 486-713 Range on HMM: 1-255/255 Sequence Identity: 21% (56 aa) RAKWMEVPMRLTVSASAVPDTVDGTYAFFAIEEEREG----GRPVPMRARFLLRPEARDA---DYYH--------FGDAYCVCVTLGQAFREYRASNVCA . || . .... . | . . .. .| .. . |. ... |. .|.| . ....| ....| ...|.| DNKWTCQETCVKI-KEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHETLHLCLRDVEMQMMCKHWANEFNQEAQHNPCP RELDFYAAYAVRVPQANIPDCIKAAVHDSDFFTRTTADSGDVM----FVAEP----EFQSFSPRCSPNADGVTEDAAGFDDLALRH----VVDAFSHFTL || .| .. | . || .. .|. .| |...|| |. || ||. .. ... | . |. .. ||||.|. KKIDFIPCYVFHFPRR-IP--AEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTT-T-SQ-R-RTEMFEYCQAFSHWTY HKSGNHLLVCHFKCQGG--------LLMHPNINTSS--GCGFETLNDGQAGIDAWARAHTCNDVC ..|. .||| || .. | | | . | || | ||.||. .. | ||..| EWSNHQMLVCDI--QGVIHKNGDLYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC |
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Kinase | LmjF36.4550.AA | Alpha | 652-713 | 30 | 0.000109 | 9.1 | In-house | 146-215 (215) | Show / Hide |
Range on Protein: 652-713 Range on HMM: 146-215/215 Sequence Identity: 30% (21 aa) AFSHFTLHKSGNHLLVCHFK-CQG-GLLMHPNINT----SSGCGFETLNDGQAGIDAWARAH--TCNDVC ||||.| .|. |.|. | ..| | | . . | | . | | .|.. ... | .||. | AFSHWTWQYSNGQLMVVDLQWGVGEWKLTDPQIHCPAKLDQGMKFGDGNCGYEGMFRFFYTHHVQCNHYC |
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Kinase | LmjF36.4550.AA | Alpha-Unclassified | 652-713 | 24 | 0.000467 | 8.94 | In-house | 144-215 (215) | Show / Hide |
Range on Protein: 652-713 Range on HMM: 144-215/215 Sequence Identity: 24% (18 aa) AFSHFTLHKSGNHLLVCHFKCQG--G-------LLMHPNINTSSGCGFE--TLNDGQAGIDAWARAH--TCNDVC ...|.| ... ..|| || . . | | | .. . | | ..|| |. | || | TYQHWTYQWTNHCDIVCDL--QGWVDENDKKTWKMTDPQIHTIR-QRYQGFKTNCGMRFIDYWFNNHHVQCNHYC |
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Kinase | LmjF36.4550.AA | VWL | 705-718 | 35 | 0.029616 | 2.63 | In-house | 193-206 (206) | Show / Hide |
Range on Protein: 705-718 Range on HMM: 193-206/206 Sequence Identity: 35% (5 aa) RAHTCNDVCKLLGM . |.||. |. | MTHQCNKYCQKLQL |
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Alpha_kinase | LmjF36.4550.AA | Alpha_kinase | 867-1101 | 30 | 9.2e-96 | 325.37 | SMART | 1-255 (255) | Show / Hide |
Range on Protein: 867-1101 Range on HMM: 1-255/255 Sequence Identity: 30% (79 aa) DFTWTPKRIFVRIVNPERGIGQGGMRVCFEVADVDPDT---CKESVMVAKMYRRTIKHVV-EKDYFM--------SVTVQKLSSLFAKDFNK--ERREGR | || ... |.| ..... ..|.||.|... |.. .. | ....|||.... .|... |..||. .| .| .. ..|..||. . .... DNKWTCQETCVKI-KEPKPFAKGAMRWCYWGCDWSEHMHCFCHGWECVAKYFKKEYKRTWDEERYFHETLHLCLRDVEMQMMCKHWANEFNQEAQ-HNPC PLLLNVLDSAVIALNRADLSAELLAKRTGFFSYRTEDTERVV----FCVEERLLGRFTKYNGNMGEAY-PTNECRLSPPAARERTMVFEAVEALSHYSLE | ....|. ..|. ..|| .....|||||.|...|. |..|... | |.||| |.|... ... .. . .. | ||..||...| ||...| PKKIDFIPCYVFHFPRR-IPAEYDRNIPYWFSYRTTDQMMVMCCCIFHMEPFMEGEFVKYNNNNGWVNDCMRWTT-T-SQ-R-RTEMFEYCQAFSHWTYE RSEGGLLVCDMQGV----RN--DLTDLEVHSYD--GQGLDMGNFGARGIEKFALRHRCTSVC .|.. .||||.||| . .|| .|..| |.|..|||.|..|||||. .|.| ..| WSNHQMLVCDIQGVIHKNGDLYYYTDPQIHTEDQNGYGFGMGNLGQEGIEKFFQTHQCNQIC |
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Alpha_kinase | LmjF36.4550.AA | Alpha_kinase | 886-1101 | 30 | 7e-69 | 239.66 | Pfam | 1-225 (225) | Show / Hide |
Range on Protein: 886-1101 Range on HMM: 1-225/225 Sequence Identity: 30% (73 aa) IGQGGMRVCFEVADV-DPDTCKESVMVAKMYRR----TIK---HVVEKDYFMSVTVQKLSSLFAKDFNKERR--EGRPLLLNVLDSA-VIALNRADLSAE ..||.||.||.. |. ||.... ...|||.|. ..| |.|..|| . .| .. ....||.. . . | ....|.. |. |.. .. FAQGAMRWCFRMFDTWDPNWRNNQNCVAKWYKKIKNYNQKQSIYVEEDYYFQDCKMQMICQQWMEKFNQKLQEHNNPPPPIEFYDCCIVYELEDHNKPDC LLAKRTGFFSYRTEDTERVVFCVEERLLG-RFTKYNGNMGEAYPTNECRLSPPAARERTMVFEAVEALSHYSLERSEGGLLVCDMQGVR--N---DLTDL .. ||||||| |.. .....| . | .|.|||.| |..| . . .. ......|.||.. .||.| ..|||.||| | ||| YQ----GFFSYRT-DWGGKYWYMEPYIEGCEFVKYNNNYGWVY---------DNMDRNDPWNQYMQAFSHFTYHRSNGQMMVCDIQGVGYNNKCYYLTDP EVHSYDGQG---LDMG--NFGARGIEKFAL-RHRCTSVC .|. ||.. .| | |.| .||||| .|.|. .| QIHTKDGNYEMDFDEGMGNLGQEGIEKFFQNQHKCNHIC |
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Kinase | LmjF36.4550.AA | Alpha | 1040-1101 | 33 | 2.9e-21 | 57.14 | In-house | 146-215 (215) | Show / Hide |
Range on Protein: 1040-1101 Range on HMM: 146-215/215 Sequence Identity: 33% (24 aa) ALSHYSLERSEGGLLVCDMQ-GVR-NDLTDLEVHS-----YDGQGLDMGNFGARGIEKFALRH--RCTSVC |.||.. ..|.| |.|.|.| || .||| .|. . ...| ||.| .|. .|. | |.. | AFSHWTWQYSNGQLMVVDLQWGVGEWKLTDPQIHCPAKLDQGMKFGD-GNCGYEGMFRFFYTHHVQCNHYC |
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Kinase | LmjF36.4550.AA | VWL | 1040-1106 | 33 | 7.1e-13 | 34.8 | In-house | 138-206 (206) | Show / Hide |
Range on Protein: 1040-1106 Range on HMM: 138-206/206 Sequence Identity: 33% (23 aa) ALSHYSLERSEGGLLVCDMQGVR-NDLTDLEVHSYDG-QGLDMGNFGARGIEKFALRHRCTSVCKSLNL |.|| . |.| ... |.||. ||| .| | . || | |. .| . | |. |..|.| AFSHFTWQYSQGYCMIVDLQGNEDGMLTDPQIHCLDQSHKFGQGNLGYEGMLRFFMTHQCNKYCQKLQL |
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Kinase | LmjF36.4550.AA | Alpha-Unclassified | 1042-1101 | 25 | 2.6e-12 | 36.3 | In-house | 146-215 (215) | Show / Hide |
Range on Protein: 1042-1101 Range on HMM: 146-215/215 Sequence Identity: 25% (18 aa) SHYSLERSEGGLLVCDMQG-VR------NDLTDLEVHSYDGQGLD--MGNFGARGIEKFALRH--RCTSVC .|.. . . . ..|||.|| | .|| .|. . |. .|.| |.| ... | | | QHWTYQWTNHCDIVCDLQGWVDENDKKTWKMTDPQIHTIR-QRYQGFKTNCGMRFIDYWFNNHHVQCNHYC |
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Kinase | LmjF36.4550.AA | ChaK | 995-1101 | 37 | 4.5e-09 | 32.12 | In-house | 120-219 (219) | Show / Hide |
Range on Protein: 995-1101 Range on HMM: 120-219/219 Sequence Identity: 37% (42 aa) FCVEERLLGRFTKYNGNMG-EAYPTNECRLSPPAARERTMVFEAVEALSHYSLERSEGGLLVCDMQGVRNDLTDLEV-HSYDGQGLDM----GNFGARGI | .|. . | | ||| | | | ||| | |. | ||. | | ||| |.||| ||| | . | || | | | FTIEKCMTGEFRKYNNNNGDEIIPTN--------TLEEIML-----AFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEEKQSCDMVFGPANLGEDAI EKFALRHRCTSVC | .| | | | RNFRAKHHCNSCC |