Gene LmjF22.0950 (L.major)

LmjF22.0950

Species: L.major
Alias: LmajK114, LmjF22.0950
External Links:
Annotation:

Classification

Group: Other
Family: NEK
Subfamily: NEK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF22.0950.AA Protein None 358 None Fasta, JSON
LmjF22.0950.kin_dom Protein Kinase Domain None 269 None Fasta, JSON

Protein domain

Protein domains of LmjF22.0950.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF22.0950.AA NEK 44-312 31 3.1e-83 282.82 In-house 1-286 (286) Show / Hide 
Range on Protein: 44-312
Range on HMM: 1-286/286
Sequence Identity: 31% (95 aa)

YRVRRAIGRGAFSTVWLLINNKTGKT-----VVGKLSDASHSSSACKAFAE-AEVENMRCCSHPNIISLIETFEAGE-KSLYI-LEYAN-AGDLQAQVDT
|.. . ||.|.|..|..    ..||      .| |  . .. |.  |  |   ||   .   ||||.. .. |.  .  .|.|  ||..  |||. .. .
YEIIKKIGQGSFGKVYKVRRKSDGKHLVEKLYVWKKINMGNMSEKEKQNAQNNEVRILKQLKHPNIVKYYDSFIEEQNNCLCIVMEYCEGGGDLYQKIKS

RAQPPPGTSDGTSIPYR--------EDEVLVIFAQLGLAIRYLHDR-----RIMHRDLKTSNVLLTRSGL----IKLGDFGFSRQYQESVSGEVGKT-FC
             |  .        |.... .|.|. ||..|.|||     .|.|||.|..|. ||...     .|.|||| |.. . ..  .  .| . 
-------------IKKQKQKGKYFEEEQIWDWFIQMCLALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISKVLNHTT--DMAYTTQV

GTPYYLAPEMWQRQSYSYKADIWSLGVIMYELLAL--KKPFQAT--NLSELMEMVTRQGSFDPLPEDR-YSSDMISLVNQMLRVDPSERPSIKDILALPL
|||||..||..| ..|..|.||||||.. ||. .|  |.||.|.  |. .|.  ...   ..|.|. | ||.|. .|..|||..||..|||...||..|.
GTPYYMSPEVCQNKPYNNKSDIWSLGCVLYEMCTLKPKHPFEAWDMNMPSLYMKIMKGPQYPPIPSHRMYSQDLQNLISQMLQKDPEQRPSCNQILEMPF

F
 
I
Kinase LmjF22.0950.AA S_TKc 44-312 28 3.5e-80 273.62 SMART 1-231 (231) Show / Hide 
Range on Protein: 44-312
Range on HMM: 1-231/231
Sequence Identity: 28% (79 aa)

YRVRRAIGRGAFSTVWLLINNKTGKTVVGKLSDASHSSSACKAFAEAEVENMRCCSHPNIISLIETFEAGEKSLYILEYANA--GDLQAQVDTRAQPPPG
|.. | ||.|||..|.. ...|||. |  |  .           .. |.. ..   ||||. |...|.  ..   ..||..   |||    . |  ....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

TSDGTSIPYREDEVLVIFAQLGLAIRYLHDRRIMHRDLKTSNVLLTRSGLIKLGDFGFSRQYQESVSGEVGKTFCGTPYYLAPEMWQRQSYSY-KADIWS
       |. | ..  ...|. .|. |.|...|.||||| .|.||..   ||..|||..||.         .||||||.|.|||.    .|.. |.|.||
------FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWS

LGVIMYELLALKKPFQATNLSELMEMVTRQGSFDPLPEDRYSSDMISLVNQMLRVDPSERPSIKDILA-------LPLF
.|.|.||.|. . ||.  .. ......              |..........|..||..||.. ..|.        | |
CGCILYEMLCGYPPFP--QMQMMFKKIG-------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF22.0950.AA Pkinase 44-312 27 1.2e-78 272.35 Pfam 1-293 (293) Show / Hide 
Range on Protein: 44-312
Range on HMM: 1-293/293
Sequence Identity: 27% (85 aa)

YRVRRAIGRGAFSTVWLLINNKTGKTVVGKLSDASHSSSACKAFAEA--EVENMRCCSHPNIISLIETFEAGEKSLY-ILEYANAG----DLQ----AQV
|.. | ||.|.|..|.. .. .|||.|. |  . .| .| ..  .    |.. |. ..||||. |...||  ....| ..||.. |    ||     .  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIST--

DTRAQPPPGTSDGTSIPY--REDEVLVIFAQLGLAIRYLHDRRIMHRDLKTSNVLLTRSGLI----KLGDFGFSRQYQESVSGEVGKTFCGTPYYLAPEM
              . ..   |.|.  .. |.  .. |.|...|.||||| .|.|. . | |    |..|||...|..   ...  .||||||.|.||| 
------------WRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEV

WQ-RQSYSYKADIWSLGVIMYELLALKKPFQAT----NLSELMEMVTRQGSFDPLPEDRYS---------------------SDMISLVNQMLRVDPSER
 . .| |..|.|.||.|.|.||.|  . ||.      |  . |.|. | .. ..  .  ..                     ........ .|..||..|
IRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKR

PSIKDILALPLF
|....||  | |
PTAEQILQHPWF
Kinase LmjF22.0950.AA CAMK 49-312 21 5.7e-74 237.55 In-house 1-425 (425) Show / Hide 
Range on Protein: 49-312
Range on HMM: 1-425/425
Sequence Identity: 21% (92 aa)

AIGRGAFSTVWLLINNKTG------------KTVVGKL--------------------------SDASHSSSACKAFAEAEVENMRCCS-------HPNI
 .|||.|..| | |. .|.            . |  |                           ..... .   ... . |.| |. ..       ||||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

ISLIETFE------------AGEK-------SLYIL----EYANAG----DLQAQVDTR-------AQPPPGTSDGTS------IPYREDEVLVIFAQLG
|.|.|..|              .|        .|.     ||.  |    ||   .  .       .                   . |.|.  .| |. 
IKLYEVYEDPHYFKNTNDYET-SKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFD----------QFDIVERGRFTEREARRYFRQIC

LAIRYLHDRRIMHRDLKTSNVLLTRS-----------------GLIKLGDFGFSRQYQESVS---------------------GEVGKTFCGTPYYLA-P
 |..|.|.. |.|||||  |.||. .                 . ||. ||||....... .                     |.  |||||||.| | |
SAVHYCHSHNIVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAP

EMWQRQS--------------YSYKADIWSLGVIMYELLALKKPFQAT-------------NLSELMEMVTRQG-SFDPLP------------EDRYSSD
|. ....              |..|.|.||.|||.| .|  . ||..              |..||.|....   .|.| .             |. | .
EVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDE

--------MISLVNQMLRVDPSERPSIKDILALPLF
         ..|...||.|||..|..|...|. | .
FHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF22.0950.AA NEK1 44-312 35 1.5e-70 240.72 In-house 1-276 (276) Show / Hide 
Range on Protein: 44-312
Range on HMM: 1-276/276
Sequence Identity: 35% (101 aa)

YRVRRAIGRGAFSTVWLLINNKTGKTVVGKLSDASHSSSACKAFAEAEVENMRCCSHPNIISLIETFEAGEK-SLYIL-EYANAGDLQAQVDTRAQPPPG
| . ..|| |.|  .||      |.. | |    . ...  .  .  ||   .   ||||... | ||.. .  |||  ||...|||      .      
YHYIKQIGEGSFGKAWLVKHKEDGQHYVIKEINVMKMQEKEREESMNEVAILAKMKHPNIVKYKESFEENGCGILYIVMEYCDGGDLMQKINRQ------

TSDGTSIPYREDEVLVIFAQLGLAIRYLHDRRIMHRDLKTSNVLLT--RSG---------------LIKLGDFGFSRQYQESVSGEVGKTFCGTPYYLAP
.  | ...  ||. .  | |. ||  . |||.|.|||.|..|. ||  ..|               |.|||||| .|  ....  |  .|  |||||| |
KRKGKLFS--EDQIMHWFCQICLALNHIHDRKILHRDIKSQNIFLTISKNGMGSGSGSGSSNDSIPLVKLGDFGIARMLNHTM--EYACTCIGTPYYLSP

EMWQRQSYSYKADIWSLGVIMYELLALKKPFQATNLSELMEMVTRQGSFDPLPEDRYSSDMISLVNQMLRVDPSERPSIKDILALPLF
|..| . |  | ||||||.. |||..|| ||.| |.  |   .. ||.. |.|  .|| .  ||| ||....|. |||. .||  |  
EICQNKPYNNKSDIWSLGCVLYELCTLKHPFEANNWKNLVLKIC-QGTYPPIPP-HYSYELQSLVSQMFKRNPRHRPSVNQILERPFI
Kinase LmjF22.0950.AA NEK8 100-312 35 9.6e-68 192.44 In-house 59-278 (278) Show / Hide 
Range on Protein: 100-312
Range on HMM: 59-278/278
Sequence Identity: 35% (80 aa)

HPNIISLIETFEAGEKSLYI-LEYANAGDLQAQVDTRAQPPPG--TSDGT---------SIPYREDEVLVIFAQLGLAIRYLHDRRIMHRDLKTSNVLLT
|||||| .. |.  ...| | .|||. | |      .     .   .. .          | . | ..|  | |  .|....|.  | |||||| |...|
HPNIISYYDHFME-DNTLMIEMEYADGGTLYQMIQHQQ----NKLFEEERQLKQVNHCFNIYFNEQMILWYFFQMCSAVHHMHQHNILHRDLKTQNIFMT

RS-GLIKLGDFGFSRQYQESVSGEVGKTFCGTPYYLAPEMWQRQSYSYKADIWSLGVIMYELLALKKPFQATNLSELMEMVTRQG-SFDPLPEDRYSSDM
|. ...|.|||| |       .    ||  |||||. ||| . ..|  | |.|.|| . ||.. ||. | |.||..|    . |.  . |.. |.||..|
RHRMVVKIGDFGISKIMNTKYHMQTTKTVVGTPYYMSPEMCEGKPYNQKSDMWALGCVLYEMCCLKRAFEASNLPALVWKIM-QCRAYEPIS-DHYSNEM

ISLVNQMLRVDPSERPSIKDILALPLF
..|| . | .||  |||   |.| || 
RMLVHNCLQQDPEQRPSASQIMAMPLC
Kinase LmjF22.0950.AA CAMKL 44-312 28 9.8e-64 202.22 In-house 1-297 (297) Show / Hide 
Range on Protein: 44-312
Range on HMM: 1-297/297
Sequence Identity: 28% (89 aa)

YRVRRAIGRGAFSTVWLLIN-NKTGKTVVGKLSDASHSSSACKAFAEA-------------EVENMRCCS---HPNIISLIETFEAGEK------SLYIL
||. . .|.|.|..| | ..   ||. |  |  | .  .  ... .               |.. |.  .   |||||.| |..|  |.         ..
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EYANAGD------LQAQVDTRAQPPPGTSDGTSIPYREDEVLVIFAQLGLAIRYLHDRRIMHRDLKTSNVLLTRSG--LIKLGDFGFSRQYQE--SVSGE
||.  |.      .... . |             .  |.|   .| |.  |. |.|...| |||.|  |.||. .|   ||. ||||| .|..    .|.
EYCSGGEMDLFDYIVKHGHRR------------GRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPCIFGPGQ

VGKTFCGTPYYLAPEMWQR--QSYS-YKADIWSLGVIMYELLALKKPFQATNL-------SELMEMVTRQGSFDPLPEDRYSSDMISLVNQMLRVDPSER
  |||||.| | |||. |.  ..|  .|.||||.|||.| ..  . || . ..         ...  ...| . | .  . | | ..|  .|| |.|..|
KLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKR

PSIKDILALPLF
|.|..|.  | .
PTIHQIMNHPWM
Kinase LmjF22.0950.AA Ciliate-E2 44-312 22 1.3e-59 203.32 In-house 1-365 (365) Show / Hide 
Range on Protein: 44-312
Range on HMM: 1-365/365
Sequence Identity: 22% (87 aa)

YRVRRAIGRGAFSTVWLLINNKTGK------------------TVVGKLSDASHSSSACKAFAEAEVENMRCCS----------------HPNIISLIET
| . . ||.|.|..|..  . |..|                   | .|.      .   . . . |   ||.                  ||||| ..|.
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

FE--AGEKSLYILEYANAGDLQA-------------QVDTRAQPPPGTSDGTSIPYREDEVLVIFAQLGL---------------AIRYLHDRR-IMHRD
|.    ..  ...||.. |||.              .                 .. | |.. |..|.                 |..||| .  |.|||
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIE------------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRD

LKTSNVLLTRSGLIKLGDFGFSRQYQES------------------VSGEVG-----------KTFCGTPYYLAPEMWQRQS---------YSYKADIWS
.| .|.|.     ||. |||.|..|...                   |.  |           .|.||||.|.|||. ....         |.||.||||
IKPENILF-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWS

LGVIMYELLALKKPFQATNLSELMEMVTR-QGSFDPL--------------PEDRYSSDMISLVNQ----MLRVDPSERPS-IKDILALPLF
||||.||.|  | ||        ..     . .|..                 .  | ... | ..    || .||..|.. ...||  | |
LGVILYEMLFGKPPF--------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF22.0950.AA Ciliate-E2-Unclassified 44-312 23 7.4e-59 201.85 In-house 1-352 (352) Show / Hide 
Range on Protein: 44-312
Range on HMM: 1-352/352
Sequence Identity: 23% (86 aa)

YRVRRAIGRGAFSTVWLLINNKTGKTVVGKLSDASHSSSACKA-------FAEAEVENM----------------RCCSHPNIISLIETFEAGEKSLYIL
|.. . ||.|.|..|......|...  . |    ... . ..        . . |..|.                . . ||.|. ....|.  ..   ..
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIVM

EYANAGDLQA---------QVDTRAQPPPGTSDGT--------SIPYREDEVL-----VIFAQLGLAIRYLHDR-RIMHRDLKTSNVLLTRSG---LIKL
||.. |||.          |.            |         .    | ...      .|||. ... |||    | |||.| .|.|.. .|    ||.
EYCEGGDLWQYIKKRKKQKQK------------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKI

GDFGFSRQYQESVS-------------GEVGKTFCGTPYYL----APEMWQRQSYS----YKADIWSLGVIMYELLALKKPFQATNLSE-----------
 |||.|..||...               .  .||||||.|.    |||. |.| |.    ||.||||||||.||.|  . ||...|  .           
IDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINN

-----LMEMV-TRQGSFDPLPE----DRYSSDMISLVN----QMLRVDPSERPSIKDILALPLF
     | .    .. .|.. |.    .. |   . ..|    .|| ..|..|.....||  |.|
AYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase LmjF22.0950.AA NEK4 44-312 35 2.3e-58 200.21 In-house 1-257 (257) Show / Hide 
Range on Protein: 44-312
Range on HMM: 1-257/257
Sequence Identity: 35% (95 aa)

YRVRRAIGRGAFSTVWLLINNKTGKTVVGKLSDASHSSSACKAFAEAEVENMRCCSHPNIISLIETFEAGEK-SLYI-LEYANAGDLQAQVDTRAQPPPG
|   . .|.| .  |||  . . .|  | |  .    |.  .  || |.. .    ||||..  | .| ..   ||| . . . |||  .   .      
YCHMKVVGKGSYGEVWLVRHRRDKKQYVMKKMFLKNASRRERKAAEHEAQLLSQLKHPNIVEYKESWEIENGQFLYIVMGFCEGGDLYRKLKQQK-----

TSDGTSIPYREDEVLVIFAQLGLAIRYLHDRRIMHRDLKTSNVLLTRSGLIKLGDFGFSRQYQESVSGEVGKTFCGTPYYLAPEMWQRQSYSYKADIWSL
   .  ..  |  |.  | |  .|  |.|...|.|||||| |. ||.  .||.|||| ||  ..  .... ||  |||||. ||..  . | || |||||
---NQFLE--EYQVVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKKNIIKIGDFGISRVLNN--HCDMAKTMIGTPYYMSPECFGNRPYDYKSDIWSL

GVIMYELLALKKPFQATNLSELMEMVTRQGSFDPLPEDRYSSDMISLVNQMLRVDPSERPSIKDILALPLF
|  .||.  ||  |.| ..  |.  .  ||   |.| . || |.  || |||   | .|||| ||.  |  
GCCVYEMITLKHAFDAKDMNSLIYQII-QGQPPPMPPN-YSQDLQNLVYQMLEKQPTKRPSIFDIFQMPYI
Kinase LmjF22.0950.AA ULK 44-312 23 7.8e-55 188.49 In-house 1-329 (329) Show / Hide 
Range on Protein: 44-312
Range on HMM: 1-329/329
Sequence Identity: 23% (80 aa)

YRVRRAIGRGAFSTVWLLINNKTGKTVVGKLSDASHSSSA-CKAFA------------EAEVENMRCCS--------HPNIISLIETFEAGE-KSLY-IL
| ... .| |.| .|   .|.||..  |...  .   ..  .. .             . |...|.           ||||. |.. ||    . .| |.
YCLNHCLGKGSFGKVYKGRNKKTKD-YVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIM

EYANAGDLQAQVDTR-------AQPPPGTSDGTSIPYREDEVLVIFAQLGLAIRYLHDRRIMHRDLKTSNVLLTRS------------GLIKLGDFGFSR
|| | |||.    ..                 .     |.|.. .| |.  . ..||...|.|||.| .|.|..              | .|..||||..
EYCNGGDLEQYIKKNKKLPEDTE---------EKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAK

QYQES-VSGEVGKTFC------GTPYYLAPEMWQ----RQSYS-YKADIWSLGVIMYELLALKKPFQATNLSELM-----EMVT-----------RQGSF
. ... .. .. .|.       |||.| ||. .|    .. |. ||.||||||.|.||.|  | ||.|   ...      . .            ..  |
HVDNDNMEQQMMMTCVNEKRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAW-FNDQYLQIIQKLINNPPPWPQQIKKQPLQF

DPL-PEDRYSSDMISLVNQMLRVDPSERPSIKDILALPLF
..  ...  |.....|  .|| .|...| |. .... |.|
PKDGNDPQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase LmjF22.0950.AA ULK 91-312 25 1.8e-47 164.04 In-house 60-324 (324) Show / Hide 
Range on Protein: 91-312
Range on HMM: 60-324/324
Sequence Identity: 25% (70 aa)

EVENMRCCS---HPN--IISLIETFEAGE-KSLY-ILEYANAGDLQAQVDTR------AQPPPGTSDGTSIPYREDEVLVIFAQLGLAIRYLHDRRIMHR
|...|.      |||  |. |.. ||    . .| |.|| | |||.    ..                .     |.|.. .| |.  . ..||.. |.||
EIQIMKKLKELKHPNHHIVKLYDWFETSNHNNIYIIMEYCNGGDLEQYIKKNKKLPETE---------EKKRLSEQEAIQFFKQICNGFKELHKHNIIHR

DLKTSNVLLTR------------SGLIKLGDFGFSRQYQE-SVSGEVGKTFC------GTPYYLAPEMWQ----RQSYS-YKADIWSLGVIMYELLALKK
|.| .| |..             .| .|..||||... .. . .  . .|..      |||.| ||. .|    .. |. ||.||||||.|.||.|  | 
DIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNNNMEQQMCQTCVNEKRIKGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKY

PFQATNLSELM----EMVTR---------QGSFDPL---PEDRYSSDMISLVNQMLRVDPSERPSIKDILALPLF
||..   ...     ...           .  ...    ...  |.....|  .|| .|...| |. .|.. |.|
PFFSW-FNDQYLYIQKLINNGKEQQIYIKNQPIQFPKPPKDPKISPECKDLIRRMLQYDEKDRISWEEIFNHPWF
Kinase LmjF22.0950.AA TyrKc 44-312 22 2.1e-17 58.6 SMART 1-280 (280) Show / Hide 
Range on Protein: 44-312
Range on HMM: 1-280/280
Sequence Identity: 22% (68 aa)

YRVRRAIGRGAFSTVWLLINNKTGKTVVGKLSDASHSSSACKAFAEAEVENMRCC--SHPNIISLIETFEAG-------EKSLYILEYANAGDLQAQV-D
 .  . .|.||| .|.. . .    .|  |   ...     ..| . | . |.    .||||. |.     .       |  . ..||.  |||.    .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA----REDFMR-EARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRK

TRAQPPPGTSDGTSIPYREDEVLVIFAQLGLAIRYLHDRRIMHRDLKTSNVLLTRSGLIKLGDFGFSRQYQES----VSGEVGKT-F--CGTP----YYL
.| .               .. | .  |     .|||.... |||| . |.|... . .| .||| ||   .     .|... ..    .|        .
HRPK------------LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

APEMWQRQSYSYKADIWSLGVIMYELLAL-KKPFQA-----TNLSELMEMVTRQGSFDPLPED-------RYSSDMISLVNQMLRVDPSERPSIKDILAL
||| ..   .. | |.|| || |.|.. . ..|         . .|..| | .||   | |..       . ...| ..  |  . ||..||. ..|   
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYV-KQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--H

PLF
 .|
ECF
Kinase LmjF22.0950.AA Pkinase_Tyr 168-201 41 1.2e-05 19.79 Pfam 126-159 (270) Show / Hide 
Range on Protein: 168-201
Range on HMM: 126-159/270
Sequence Identity: 41% (14 aa)

YLHDRRIMHRDLKTSNVLLTRSGLIKLGDFGFSR
||..... |||| . |.|.|... .| .||| .|
YLESKNCIHRDLAARNCLVTENNVVKICDFGLAR
Kinase LmjF22.0950.AA Pkinase_Tyr 222-271 28 0.000636 13.91 Pfam 181-232 (270) Show / Hide 
Range on Protein: 222-271
Range on HMM: 181-232/270
Sequence Identity: 28% (15 aa)

LAPEMWQRQSYSYKADIWSLGVIMYELLAL-KKP-FQATNLSELMEMVTRQG
.||| ..   .. | |.|| || |.|.. . ..| ..    .|..|.....|
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDG
Kinase LmjF22.0950.AA ULK 44-70 29 0.00299 7.46 In-house 1-31 (324) Show / Hide 
Range on Protein: 44-70
Range on HMM: 1-31/324
Sequence Identity: 29% (9 aa)

YRVRRAIGRGAFS-TVWLLINNKT---GKTV
| ... .| |.|  .|   .|.||   .. |
YCLNHCLGKGSFGVKVYKGRNKKTNTQNQYV
Kinase LmjF22.0950.AA Pkinase_Tyr 44-107 22 0.675871 3.66 Pfam 1-70 (270) Show / Hide 
Range on Protein: 44-107
Range on HMM: 1-70/270
Sequence Identity: 22% (16 aa)

YRVRRAIGRGAFSTVWLLINN----KTGKTVVGKLSDASHSSSA--CKAFAEAEVENMRCC-SHPNIISLI
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ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR-EAKIMKQLGHHPNIVRLY