Gene LmjF01.0750 (L.major)

LmjF01.0750

Species: L.major
Alias: LmjF01.0750, LmajK094
External Links:
Annotation:

Classification

Group: CMGC
Family: SRPK

Sequence

Name Sequence Type Origin Length Description Download
LmjF01.0750.AA Protein None 1417 None Fasta, JSON
LmjF01.0750.kin_dom Protein Kinase Domain None 981 None Fasta, JSON

Protein domain

Protein domains of LmjF01.0750.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF01.0750.AA CMGC 1087-1125 33 7.8e-14 40.93 In-house 286-342 (513) Show / Hide 
Range on Protein: 1087-1125
Range on HMM: 286-342/513
Sequence Identity: 33% (19 aa)

VQSREYRAPEVLLGNFVL----------PACDIWSMGCIAYELVSG--------RFL
|..| |||||.|||              ...|.|| ||| .|.. |        . |
VVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPL
Kinase LmjF01.0750.AA SRPK 405-656 18 8.1e-14 30.44 In-house 1-160 (554) Show / Hide 
Range on Protein: 405-656
Range on HMM: 1-160/554
Sequence Identity: 18% (48 aa)

YTLLKALGVGRSSRVWLAVDLEQCSLARCQLIRELGEREVRRLFRTSERPMFVAIKVFRCDPVYADCAMYELKLSALIHENVMTR------QQQEQEQQR
|.. . || |  | |||. |                           ..  .||.|. . .|.|   |  |.||   . ..  .       ..  ....|
YHVIRKLGWGHFSTVWLCWD--------------------------MQYDRYVAMKIVKSAPHYTETAVDEIKLLQCVRKHDPNPQWMHFLKEYYEDYKR

WPPARASHSASLPSSLIAVPAACDDPGGDLQESSDGGENSTSRGRDGAAGRTRADSASSTPGSGSVSAEVASPASTSAMAFS-RRLTTVR--DAFTIEGA
                                                                                |. .| . |.  | |.. | 
----------------------------------------------------------------------------DCKEFDPNRCHVVQLLDHFKHRGP

FGTHQCLVMDVLGAGVDRAINEAHLNGFPSAVARSIMQSSLQGLVLL-AACHLVHTDMKPEN
 |.| |.|  |||      |      | | . ...|..  |.||. |   |   ||| ||||
NGNHYCMVFEVLGHNLLKWIKHYNYQGMPMHCVKQIARQVLIGLDYLHRKCGIIHTDIKPEN
Kinase LmjF01.0750.AA SRPK 1088-1125 47 4.2e-13 28.55 In-house 414-451 (554) Show / Hide 
Range on Protein: 1088-1125
Range on HMM: 414-451/554
Sequence Identity: 47% (18 aa)

QSREYRAPEVLLGNFVLPACDIWSMGCIAYELVSGRFL
| |.||.|||..|    .  ||||  | |.||  | .|
QTRQYRSPEVIIGAGYNTPADIWSTACMAFELATGDYL
Kinase LmjF01.0750.AA SRPK 1351-1385 51 7.4e-13 27.9 In-house 520-554 (554) Show / Hide 
Range on Protein: 1351-1385
Range on HMM: 520-554/554
Sequence Identity: 51% (18 aa)

SAEEAADFEVFLLRCLQWDPARRATAAELLADKWL
| |||..|| ||.  |. .|  ||||.|.|  .||
SHEEAKQFEDFLMPMLHYNPEKRATAKECLQHPWL
Kinase LmjF01.0750.AA CLK 1086-1122 55 1.3e-12 33.4 In-house 207-243 (350) Show / Hide 
Range on Protein: 1086-1122
Range on HMM: 207-243/350
Sequence Identity: 55% (21 aa)

VVQSREYRAPEVLLG-NFVLPACDIWSMGCIAYELVSG
.|..| |||||| ||  .  | ||.|| ||| .||..|
IVSTRHYRAPEVILGLGWSQP-CDVWSIGCILFELYTG
Kinase LmjF01.0750.AA Pkinase 1089-1125 44 3e-12 44.4 Pfam 174-211 (293) Show / Hide 
Range on Protein: 1089-1125
Range on HMM: 174-211/293
Sequence Identity: 44% (17 aa)

SREYRAPEVLL-GNFVLPACDIWSMGCIAYELVSGRFL
...|.||||.. |.   |..|.||.||| ||...||..
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPP
Kinase LmjF01.0750.AA DYRK2 1087-1122 58 5e-12 35.06 In-house 163-198 (318) Show / Hide 
Range on Protein: 1087-1122
Range on HMM: 163-198/318
Sequence Identity: 58% (21 aa)

VQSREYRAPEVLLGNFVLPACDIWSMGCIAYELVSG
.||| |||||| ||  .  | |.|| |||. ||..|
IQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTG
Kinase LmjF01.0750.AA S_TKc 405-1385 5 1.3e-11 -6.83 SMART 1-231 (231) Show / Hide 
Range on Protein: 405-1385
Range on HMM: 1-231/231
Sequence Identity: 5% (58 aa)

YTLLKALGVGRSSRVWLAVDLEQCSLARCQLIRELGEREVRRLFRTSERPMFVAIKVFRCDPVYADCAMYELKLSALIHENVMTRQQQEQEQQRWPPARA
|..|. .| |  ..|..... .                              ||||. .                                         
YEILRKIGKGAFGKVYKCRHKK--------------------------TGRIVAIKIIK-----------------------------------------

SHSASLPSSLIAVPAACDDPGGDLQESSDGGENSTSRGRDGAAGRTRADSASSTPGSGSVSAEVASPASTSAMAFSRRLTTVRDAFTIEGAFGTHQCLVM
                                                               . .  .   .     . .  |.|       .| ..||
-------------------------------------------------------------EHIRREIQILKK-HHPNIVKLYDVFQD-----DHLYMVM

DVLGA---GVDRAINEAHLNG----FPSAVARSIMQSSLQGLVLLAACHLVHTDMKPENLFFTNLEA-----DVAEEMLTFQSAQLRASQRQTLCSSFTH
. ..     . . | .   .|    ||  .||..|.  ...|  .   . .| | ||||..... .       .| ..                      
EYCDGDLGDLFDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL----------------------

RSTATSVMTERQEVAAHEQQHHGDGGTAEHTGVGQRSPFSAPPLPDYTHVKGAAADLHTVHAANAADVGASGDRVASSVTNLSAVAVGHETLHSSQDSSA
                                                                                                    
----------------------------------------------------------------------------------------------------

QVSCQPSFARTPTRRRSAYDVRLSGLGLSLVVPPCLRLGVRVLTNYAAHAADGGGMTADELVRQDPLAQLHWLCAQQQARLLRLPGNDDDDDLGSVAERW
                                                                                                    
----------------------------------------------------------------------------------------------------

RLAGTCAPAASPPPPTLDIGMSEDFIDEAELRALGLQELPKSDADGGRCAAGMAADEYVEADVTDFVCVPAVGEPAAHHRATVTTAGVGIEDGTTLPPAT
                                                                                                    
----------------------------------------------------------------------------------------------------

LRTASAATRAGGGRRTPLAAAKRRLFPPCFHEGLATPRDPATVPTRCEGVAAASPTDSSSSGAAPPAGAAAAATVLRRLECEVVRHQNYRRGVVVQSREY
                                                                                             .. ...|
-------------------------------------------------------------------------------------------TTFCGTPWY

RAPEVLLGNFVLP-ACDIWSMGCIAYELVSGRFLIDCIVDRERFATALSWQQQQRHGRKGCHAPDDDSGGAHDAKDHSRDDDEDTQQRLNKWDGQPVYLE
.|||||      . .||.|| ||| ||...|. . .   . . |   .                                                    
MAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------------------------------------------------

DTEQDLDVFHLKAIMRLIGPPPVSFLRQQPIGLFVDDFFDEHGDFCFWERGEAEEAGMRLADPYRQLELTYWAAASRVSGTSVAVGSAAGQQQNPPLPET
                                                                                                    
----------------------------------------------------------------------------------------------------

VSGVTASLDTDPPGAPSAASVGQHAASAQARRDPQDTMNYPIRTPDWQDVQAILREKLGSAEEAADFEVFLLRCLQWDPARRATAAELLA-------DKW
                                                                 ..  |. .|||.||..| || |.|.       . |
---------------------------------------------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPW

L
.
F
Kinase LmjF01.0750.AA DYRK 1087-1125 56 8.4e-11 36.86 In-house 165-203 (320) Show / Hide 
Range on Protein: 1087-1125
Range on HMM: 165-203/320
Sequence Identity: 56% (22 aa)

VQSREYRAPEVLLGNFVLPACDIWSMGCIAYELVSGRFL
.||| ||||||.||     | |.|| ||| .||. |  |
IQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPL
Kinase LmjF01.0750.AA CAMK 1089-1124 33 2.3e-10 28.84 In-house 282-332 (425) Show / Hide 
Range on Protein: 1089-1124
Range on HMM: 282-332/425
Sequence Identity: 33% (17 aa)

SREYRA-PEVLLG--------------NFVLPACDIWSMGCIAYELVSGRF
. || | ||||.|                . |.||.||.|.| | ...|..
TPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYP
Kinase LmjF01.0750.AA DyrkP 1087-1125 53 1.1e-09 27.39 In-house 166-204 (323) Show / Hide 
Range on Protein: 1087-1125
Range on HMM: 166-204/323
Sequence Identity: 53% (21 aa)

VQSREYRAPEVLLGNFVLPACDIWSMGCIAYELVSGRFL
|||| ||||||..|       |.||.|||  ||  |  |
VQSRSYRAPEVIIGCKYDYRIDMWSLGCILAELWTGNVL
Kinase LmjF01.0750.AA Ciliate-E2 1086-1124 33 3.7e-09 27.58 In-house 247-294 (365) Show / Hide 
Range on Protein: 1086-1124
Range on HMM: 247-294/365
Sequence Identity: 33% (16 aa)

VVQSREYRAPEVLLGNFVL---------PACDIWSMGCIAYELVSGRF
.. . .| |||.| |              .|||||.|.| ||...|..
ICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGKP
Kinase LmjF01.0750.AA CDK 1092-1123 39 4e-09 25.17 In-house 185-222 (284) Show / Hide 
Range on Protein: 1092-1123
Range on HMM: 185-222/284
Sequence Identity: 39% (15 aa)

YRAPEVLLGNFVL---PACDIWSMGCIAYELVS---GR
|||||.|||       .. |.|| ||| .|..    ..
YRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRK
Kinase LmjF01.0750.AA CMGC 1361-1385 36 8.2e-09 24.12 In-house 489-513 (513) Show / Hide 
Range on Protein: 1361-1385
Range on HMM: 489-513/513
Sequence Identity: 36% (9 aa)

FLLRCLQWDPARRATAAELLADKWL
.| ..||.||..| ||.. |.  ..
LLKKMLQYDPDKRITAEQALQHPYF
Kinase LmjF01.0750.AA DYRK2 1357-1385 37 1.5e-08 23.61 In-house 290-318 (318) Show / Hide 
Range on Protein: 1357-1385
Range on HMM: 290-318/318
Sequence Identity: 37% (11 aa)

DFEVFLLRCLQWDPARRATAAELLADKWL
.|  |..||..|||. | |... |  .|.
NFIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase LmjF01.0750.AA Trio 1091-1117 48 2.6e-08 16.72 In-house 165-191 (258) Show / Hide 
Range on Protein: 1091-1117
Range on HMM: 165-191/258
Sequence Identity: 48% (13 aa)

EYRAPEVLLGNFVLPACDIWSMGCIAY
|  |||.. || | .. ||||.| ..|
EFMAPEIIQGNPVSYGTDIWSIGVLTY
Kinase LmjF01.0750.AA DYRK2 599-656 32 3.8e-07 18.95 In-house 75-132 (318) Show / Hide 
Range on Protein: 599-656
Range on HMM: 75-132/318
Sequence Identity: 32% (19 aa)

HQCLVMDVLGAGVDRAINEAHLNGFPSAVARSIMQSSLQGLVLLAACHLVHTDMKPEN
| |.. . |.  .   | . | .||  .  |   .| ||.|..|    ..| |.||||
HHCITFELLSMNLYEYIKKNHFQGFSLQLVRRFAHSILQCLRFLHKNNIIHCDLKPEN
Kinase LmjF01.0750.AA DYRK 1361-1385 44 8.3e-07 21.78 In-house 296-320 (320) Show / Hide 
Range on Protein: 1361-1385
Range on HMM: 296-320/320
Sequence Identity: 44% (11 aa)

FLLRCLQWDPARRATAAELLADKWL
|...||||||..| |... |  .|.
FIKKCLQWDPHKRITPSQALQHPWF
Kinase LmjF01.0750.AA Pkinase 1361-1385 40 2e-06 23.71 Pfam 269-293 (293) Show / Hide 
Range on Protein: 1361-1385
Range on HMM: 269-293/293
Sequence Identity: 40% (10 aa)

FLLRCLQWDPARRATAAELLADKWL
|. .||..||..| ||...| ..|.
FIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF01.0750.AA CAMK 1361-1385 32 2e-06 15.85 In-house 401-425 (425) Show / Hide 
Range on Protein: 1361-1385
Range on HMM: 401-425/425
Sequence Identity: 32% (8 aa)

FLLRCLQWDPARRATAAELLADKWL
.. ..|| || .|.|... |...|.
LIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF01.0750.AA Trio 1361-1385 40 2.6e-05 8.87 In-house 234-258 (258) Show / Hide 
Range on Protein: 1361-1385
Range on HMM: 234-258/258
Sequence Identity: 40% (10 aa)

FLLRCLQWDPARRATAAELLADKWL
|.   || ||..| .|.| |.  |.
FICKVLQEDPWKRPCASECLQHPWF
Kinase LmjF01.0750.AA DYRK 621-656 34 4.1e-05 15.39 In-house 97-134 (320) Show / Hide 
Range on Protein: 621-656
Range on HMM: 97-134/320
Sequence Identity: 34% (13 aa)

NGF-PSAVARSIMQSSLQGLVLLAAC-HLVHTDMKPEN
.|| .  . |.. |. |..|..|. .  ..| |.||||
QGFFSLNLVRKFAQQILTCLKFLHKNENIIHCDLKPEN
Kinase LmjF01.0750.AA CDK 1361-1385 28 5.9e-05 11.61 In-house 260-284 (284) Show / Hide 
Range on Protein: 1361-1385
Range on HMM: 260-284/284
Sequence Identity: 28% (7 aa)

FLLRCLQWDPARRATAAELLADKWL
.| ..|. ||..| .| . | ....
LLNKMLCYDPKKRISAEQALQHPYF
Kinase LmjF01.0750.AA Ciliate-E2 1361-1385 26 9.9e-05 12.14 In-house 336-365 (365) Show / Hide 
Range on Protein: 1361-1385
Range on HMM: 336-365/365
Sequence Identity: 26% (8 aa)

FLLR----CLQWDPARRAT-AAELLADKWL
.. .    .|| ||  | | . ..|  .|.
LIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF01.0750.AA CLK 646-661 56 0.000188 8.47 In-house 134-149 (350) Show / Hide 
Range on Protein: 646-661
Range on HMM: 134-149/350
Sequence Identity: 56% (9 aa)

HLVHTDMKPENLFFTN
.|.||| ||||  |..
KLTHTDLKPENICFVD
Kinase LmjF01.0750.AA DyrkP 1361-1385 48 0.000231 9.52 In-house 299-323 (323) Show / Hide 
Range on Protein: 1361-1385
Range on HMM: 299-323/323
Sequence Identity: 48% (12 aa)

FLLRCLQWDPARRATAAELLADKWL
|  .||| |  || || | |   |.
FVRQCLQIDFTRRPTAKEALQHPWF
Kinase LmjF01.0750.AA CMGC 616-661 22 0.001285 6.73 In-house 161-219 (513) Show / Hide 
Range on Protein: 616-661
Range on HMM: 161-219/513
Sequence Identity: 22% (14 aa)

NEAH------------LNGFPSAVARSIMQSSLQGLV--LLAACH--LVHTDMKPENLFFTN
.| |               |.    | .|.  |.||    .       .|.|.||||. ...
SE-HENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKYCHSHWGNIIHRDLKPENILINH
Kinase LmjF01.0750.AA CLK 1364-1385 27 0.001526 5.69 In-house 329-350 (350) Show / Hide 
Range on Protein: 1364-1385
Range on HMM: 329-350/350
Sequence Identity: 27% (6 aa)

RCLQWDPARRATAAELLADKWL
..|  ||..| |... |   . 
KMLEYDPSKRITCKDALQHPFF
Kinase LmjF01.0750.AA Trio 636-657 45 0.037346 0.6 In-house 105-126 (258) Show / Hide 
Range on Protein: 636-657
Range on HMM: 105-126/258
Sequence Identity: 45% (10 aa)

LQGLVLLAACHLVHTDMKPENL
|...  | .||  | | ||||.
LEAVHYLHNCHILHLDIKPENM
Kinase LmjF01.0750.AA Pkinase 405-424 20 0.16469 6.42 Pfam 1-20 (293) Show / Hide 
Range on Protein: 405-424
Range on HMM: 1-20/293
Sequence Identity: 20% (4 aa)

YTLLKALGVGRSSRVWLAVD
|.... .| | ...|.....
YHIGRKIGSGSFGCVYKCHH
Kinase LmjF01.0750.AA Pkinase 648-661 50 2.456562 2.27 Pfam 130-143 (293) Show / Hide 
Range on Protein: 648-661
Range on HMM: 130-143/293
Sequence Identity: 50% (7 aa)

VHTDMKPENLFFTN
.| |.||||... |
IHRDLKPENILIDN