Gene LmjF03.0210 (L.major)

LmjF03.0210

Species: L.major
Alias: LmjF03.0210, LmajK086
External Links:
Annotation:

Classification

Group: CMGC
Family: MAPK
Subfamily: MAPK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF03.0210.AA Protein None 379 None Fasta, JSON
LmjF03.0210.kin_dom Protein Kinase Domain None 304 None Fasta, JSON

Protein domain

Protein domains of LmjF03.0210.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF03.0210.AA CMGC 15-318 21 1e-89 294.93 In-house 1-513 (513) Show / Hide 
Range on Protein: 15-318
Range on HMM: 1-513/513
Sequence Identity: 21% (109 aa)

FQVESIIGQGAYGAVCKAVF----------------CNDQIAVKKIPHYSRSEDTAR----------RVLREIEILQNLQ----------------FCEQ
... . ||.|.|| |.|..                  | ..|.|||      |..|.          | ||||.||..|.                  . 
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VVGCRLFFRPKSEE--------------KDVYVAMDYIPADLSSVIKNGA--------ITLDESV------------VRYIT------CQLLLALR--AL
.|... .|..| ..              ...|  ..|.. ||  .|||          . |.| .            ..|..       |.| .|    .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HRCK--VLHRDVSTRNILIHYNSQV--------------------FLCDFGLSRFFDPD----------------------EQLSFGVVTQWYRAPEIIL
|. .  ..|||    ||||  | ..                     .|||||.|...|                       ....  ||| |||||||.|
HSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILL

DAA----------YSYASDVWSVGVILGELLLR--------RHLFPGKSN---------DSANQLQLIFHLVGTP----------------SKDVFDADR
 .           |... |.|||| |..|....        . ||||.|.         .  .||..|| . |||                ... ..   
GWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPTWMIQKGKRHFNFCKHEEEWPNMIK

SFGR---------------ASQNARNYALAYIERRPCP-STLVNLLSTAP----------ALHHSAIAA----------------VPPQVVQLAEQLLQF
  ..                |  ||||    .   ..|  .. ||   .|           . .. |                   .|| . | ...||.
LPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVF-NW-IYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY

DPARRPSADEALRHPWF
||..|..|..||.||.|
DPDKRITAEQALQHPYF
Kinase LmjF03.0210.AA MAPK 15-318 31 1.7e-75 257.16 In-house 1-328 (328) Show / Hide 
Range on Protein: 15-318
Range on HMM: 1-328/328
Sequence Identity: 31% (109 aa)

FQVESIIGQGAYGAVCKAVFCN--------DQIAVKKIPHYSRSEDTARRVLREIEILQNLQFCEQVVGCRLFFRP------KSEE--KDVYVAMDYIPA
.|  . ||||||| ||.|.           ...|.|||..  ...  ..|..||| .|. .   | ... .  |.|      .| |  .|.|. |..  .
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIKKISRPFQNPTHCKRTYREIKLLRHFHHHENIIKLLDIFTPEMQDDQNSLEEFNDIYIVMELMET

DLSSVIKNGAITLDESVVRYITCQLLLA--LRALHRCKVLHRDVSTRNILIHYNSQVFLCDFGLSRFFDPDE---------------QLSFGVVTQWYRA
||  .|| .  .|..  ..|.. |.| .  |  .|   |.|||    |||.  | .. .|||||.| .||..               ...  |.|.||||
DLHQIIKSQQ-PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNILVNENCDLKICDFGLARSIDPEYHHHHQQDDPHCFQKMHMTEYVATRWYRA

PEIILD---AAYSYASDVWSVGVILGELLL-RRHLFPGKSNDSANQLQLIFHLVGTPSKDVF-DADRSFGRASQNARNYALAYI-ERRPCPSTLVNLLST
|||.|      |. | |.|||| |..|.|  |. |||||  |. .|..||. ..||||...     .     |..||||   .   ... . .. .... 
PEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGK--DYIDQWNLIMEVLGTPSEEFIQCICM-----SEHARNYIQSLGNLPKYPKKPWEKMFPN

APALHHSAIAAVPPQVVQLAEQLLQFDPARRPSADEALRHPWF
|          . || . | |..|.||| .| ...|||.|| |
ANF-------NANPQAIDLLEKMLVFDPDKRITVEEALQHPYF
Kinase LmjF03.0210.AA S_TKc 15-318 24 6.2e-74 252.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 15-318
Range on HMM: 1-231/231
Sequence Identity: 24% (78 aa)

FQVESIIGQGAYGAVCKAVFCN--DQIAVKKIPHYSRSEDTARRVLREIEILQNLQFCEQVVGCRLFFRPKSEEKDVYVAMDYIPA---DLSSVIKNGAI
...  .||.||.| |.|..  .   . |.|.|.         ....|||.||..   .. .| .  .|.     ...|. |.|..    || ..||.   
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK--HHPNIVKLYDVFQD----DHLYMVMEYCDGDLGDLFDYIKKRGR

-----TLDESVVRYITCQLLLALRALHRCKVLHRDVSTRNILIHYNSQVFLCDFGLSRFFDPDEQLSFGVVTQWYRAPEIILDAAYSY-ASDVWSVGVIL
      ..| ..|....|...||  .|. ...|||.   |||.    .. .|||||.|..      .  ..| ||.|||..    |.. ..|.||.|.||
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

GELLLRRHLFPGKSNDSANQLQLIFHLVGTPSKDVFDADRSFGRASQNARNYALAYIERRPCPSTLVNLLSTAPALHHSAIAAVPPQVVQLAEQLLQFDP
 |.| .. .||        |.|..|...|                                                       .|.. .. ...||.||
YEMLCGYPPFP--------QMQMMFKKIG-------------------------------------------------------SPEAKDFIRKCLQKDP

ARRPSADEALR-------HPWF
..||.| |||.       ||||
EKRPTA-EALQDEWDIKCHPWF
Kinase LmjF03.0210.AA Pkinase 15-318 24 2.7e-67 234.66 Pfam 1-293 (293) Show / Hide 
Range on Protein: 15-318
Range on HMM: 1-293/293
Sequence Identity: 24% (80 aa)

FQVESIIGQGAYGAVCKAVFCNDQ--IAVKKIPHYSRSEDTARRVLR--EIEILQNLQFCEQVVGCRLFFRPKSEEKDVYVAMDYIPA-----DLSSVIK
......||.|..| |.|..  ...   |||.|.  .....  .. .|  ||.|...|. .. .| .. .|.    ....|. |.| .      ||...|.
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN-HPNIVRLYDWFED---KDHIYMVMEYCEGGLYVMDLFDYIS

---NGAITLDESVVRYITCQLLLALRALHRCKVLHRDVSTRNILIHYNSQV----FLCDFGLSRF--FDPDEQLSFGVVTQWYRAPEIIL-DAAYSYASD
   .|.....| ... .  |.| .|  .|.....|||.   ||||. | ..     .|||||...    ... ..  ..| ||.|||.|. .  |....|
TWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VWSVGVILGELLLRRHLFPGK--SNDSANQLQLIFHLVGTPSKDVFDADRSFGRASQNARNYALAYIERRPCPSTLVNLLSTAPALHHSAIAAVPPQVVQ
.||.|.|| |.|..| .|||.  . . ..|.|.|.   |.| .  .. ..|  . .   . .                        |     ....   .
MWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H--------------------F-HWTF-HNWSEECKD

LAEQLLQFDPARRPSADEALRHPWF
. . .|..||..||.|...| ||||
FIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF03.0210.AA CDK 15-318 26 2.7e-67 214.29 In-house 1-284 (284) Show / Hide 
Range on Protein: 15-318
Range on HMM: 1-284/284
Sequence Identity: 26% (90 aa)

FQVESIIGQGAYGAVCKAVFCN-------DQIAVKKIPHYS--RSED---TARRVLREIEILQNLQFCEQVVG-CRLFFRPKSE-------EKDVYVAMD
..    ||.|.|| | ||   .       . .| |||   .  |.|.        .||| .|..|  .. .|     .   ...       |. .|  ..
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIRMENEGREEEKEGFPITAIREISLLKEL--HPNIVKLHDVCHTKNMDRNNKDKHENKLYMVFE

YIPADLSSVIKNGAITLDESVVRYITCQLLLALRALHRCKVLHRDVSTRNILIHYNSQ-----VFLCDFGLSRFFD-------PDEQLSFGVVTQWYRAP
|.. ||.....          .. .. ||| .|  .|. ...|||  . ||||  | .     . . ||||.| |        |   ..  ||| |||||
YMDHDLKKYMD----------IKCYMWQLLRGLHYCHSNWIMHRDLKPQNILINNNGEVKCGRLKIADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAP

EIIL-DAAYS--YASDVWSVGVILGELLL---RRHLFPGKSNDSANQLQLIFHLVGTPSKDVFDADRSFGRASQNARNYALAYIERRPCPSTLVNLLSTA
|. | .  ||   . |.|||| |..|...   |. ||||.|    .|| .|| . |||. |.     ..                               
ELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSE--IDQLFKIFRICGTPTEDNWPGVTKLPDY----------------------------

PALHHSAIAAVPPQVVQLAEQLLQFDPARRPSADEALRHPWF
                .| ...|..||..| ||..|| ||.|
----------------DLLNKMLCYDPKKRISAEQALQHPYF
Kinase LmjF03.0210.AA nmo 15-318 32 7.1e-52 157.48 In-house 1-292 (292) Show / Hide 
Range on Protein: 15-318
Range on HMM: 1-292/292
Sequence Identity: 32% (102 aa)

FQVESIIGQGAYGAVCKAVFCND--QIAVKKIPHYSRSEDTARRVLREIEILQNLQFCEQVVGCRLFFRPKSE--EKDVYVAMDYIPADLSSVIKNGAIT
 | .  || ||.| |       |   .|.||.|.   .   ..|| ||. .|   .    |.  .   .|      ...||  . . .||  .|      
IQPDRPIGYGAFGVVWSVTDPRDGKRVALKKMPNVFQNLVSCKRVFRELKMLCFFKHDN-VLSALDILQPPHKDFFQEIYVVTELMQSDLHKIIVS-PQH

LDESVVRYITCQLLLALRALHRCKVLHRDVSTRNILIHYNSQVFLCDFGLSRFFDPDEQLSFG--VVTQWYRAPEIILDA-AYSYASDVWSVGVILGELL
|    |.    |.|  |. ||  ..||||.   |.|.  |  . .||||| |  ..|...     ||||.||||||.. |  |. | |.|||| | .|||
LSSDHVKVFLYQILRGLKYLHSANILHRDIKPGNLLVNSNCVLKICDFGLARVWEQDQSKHMTQEVVTQYYRAPEILMGARHYTSAVDIWSVGCIFAELL

LRRHLFPGKSNDSANQLQLIFHLVGTPSKDVFDADRSFGRASQNARNYALAYIERRPCPSTLVNLLSTAPALHHSAIAAVPPQVVQLAEQLLQFDPARRP
 || ||  .     .|||.|  |.|||| .          | . |..  |   .. || . | .| |   | |           |.|  ..| ||| .| 
GRRILF--QAQSPIQQLQMITDLLGTPSMEDMKY------ACEGAKAHMLRMPHKPPCLQVLYTLSSPDHATH---------EAVHLLCRMLHFDPDKRI

SADEALRHPWF
|. .|| ||. 
SCKDALAHPYL
Kinase LmjF03.0210.AA ERK 15-318 32 2.4e-50 173.56 In-house 1-307 (307) Show / Hide 
Range on Protein: 15-318
Range on HMM: 1-307/307
Sequence Identity: 32% (107 aa)

FQVESIIGQGAYGAVCKAVFCN-------DQIAVKKIPHYSRSEDTARRVLREIEILQNLQFCEQVVGCRLFFRPKSEE--KDVYVAMDYIPADLSSVIK
.|  . ||.|||| ||.|.. .       . .|.|||.     .  . | |||| .|  .   | ... .  ..|.| |  .|.|.  ...  ||  .|.
YQIIKQIGHGAYGVVCSAIDKEYCFDETGQKVAIKKIENAFDHPIYCKRTLREIKLLRHFKGHENIICLFDIMMPNSPEQYNDIYCVEELMETDLHQIIN

NGAITLDESVVRYITCQLLLALRALHRCKVLHRDVSTRNILIHYNSQVFLCDFGLSRFFDP---------DEQLSFGVVTQWYRAPEIILDAA-YSYASD
.   .| .  . | . |.| .|  .|  .|.|||   .|||.  | .   |||||.|.||.         .....  |.| |||||||.| .  |. | |
SQQ-ELSDDHCQYFMYQILCGLKYIHSANVIHRDLKPSNILVNSNCDLKICDFGLARCFDASYQENHECNQNFMTEYVATRWYRAPEIMLSWQKYTKAMD

VWSVGVILGELLLRRHLFPGKSNDSANQLQLIFHLVGTP-SKDVFDADRSFGRASQNARNYALAYIE--RRPCPSTLVNLLSTAPALHHSAIAAVPPQVV
.||.|.|. |.| |. |||||  |. .|...|| . ||| |.. .        .|.||..|   . .  | | |  . |. ..|.         . || .
IWSCGCIFAEMLGRKPLFPGK--DYVHQINRIFQIIGTPHSEEDLQY-----ICSENAWKYIKNLPNPVRPPKP--WENIFPNAN---------CNPQAI

QLAEQLLQFDPARRPSADEALRHPWF
 | |..|.|||  | ...|.|.|| |
DLLEKMLVFDPDKRITVEECLEHPYF
Kinase LmjF03.0210.AA ERK7 15-236 34 1.4e-48 164.15 In-house 1-228 (292) Show / Hide 
Range on Protein: 15-236
Range on HMM: 1-228/292
Sequence Identity: 34% (81 aa)

FQVESIIGQGAYGAVCKAVF--CNDQIAVKKIPHYSRSEDTARRVLREIEILQNLQFCEQVVGCRLFFRPKSEEKDVYVAMDYIPADLSSVIKNGAITLD
..... .|.|||| | ||.     . .|.|||    | .  | |  ||| .||...  . ..     .| .  ..|.|.. ..  .||  ||. | | | 
YEIRKRLGKGAYGIVWKAYDKRTKQVVALKKIFDAFRNQTDAQRTFREIMFLQEFHCHPNIIRLINVIRAD-NDRDIYLVFEFMETDLHAVIRKGNI-LK

ESVVRYITCQLLLALRALHRCKVLHRDVSTRNILIHYNSQVFLCDFGLSRFFDPDE-------QLSFGVVTQWYRAPEIILDA-AYSYASDVWSVGVILG
.  ..|| .||| |.. .|  .|.|||.   |||.  .  | .||||| |     |        |   | | ||||||| | .  |  . | ||.| |||
DIHKQYIMYQLLRAIKYMHSGNVIHRDLKPSNILLDSECMVKVCDFGLARSIAQQEEYDEQNPMLTEYVATRWYRAPEILLGSHRYTKGVDMWSIGCILG

ELLLRRHLFPGKSNDSANQLQLIFHLVGTPSK
|.|  . .||| |    ||. .| .... |..
EMLRGKPMFPGTS--TMNQIEKILETIPKPTQ
Kinase LmjF03.0210.AA ERK5 15-241 38 4.4e-45 156.1 In-house 1-235 (295) Show / Hide 
Range on Protein: 15-241
Range on HMM: 1-235/295
Sequence Identity: 38% (92 aa)

FQVESIIGQGAYGAVCKAV--FCNDQIAVKKIPHYSRSEDTARRVLREIEILQNLQFCEQVVGCRLFFRPK---SEEKDVYVAMDYIPADLSSVIK-NGA
...   ||.|||| || |.     .|.|.||||       .|.| .||. ||.  .  . ..  |   .||   || ||||| .| . .||  .|  |  
YKIIEKIGNGAYGVVCSARRRKNGQQVAIKKIPNAFDVVTNAKRTFRELKILRHFRH-DNIIAIRDILMPKVPYSEMKDVYVVFDLMESDLHQIIHSNQP

ITLDESVVRYITCQLLLALRALHRCKVLHRDVSTRNILIHYNSQVFLCDFGLSR---FFDPDEQLSFG---VVTQWYRAPEIILDAA-YSYASDVWSVGV
.||.   .||   |.|  |. .|  .|.|||.   |.|.  |  . . |||. |    | ||..  |    | | ||||||...    |  | |||||| 
FTLEH--IRYFLYQILRGLKYMHSAQVIHRDLKPSNLLVNENCELKIGDFGMARGLCTFSPDKHQMFMTEYVATRWYRAPELMFSSHDYTQAIDVWSVGC

ILGELLLRRHLFPGKSNDSANQLQLIFHLVGTPSKDVFDA
|.||.. || .||||     .|||||   .|.|.  .  |
IFGEMIARRQMFPGK--NYIHQLQLIMMVLGMPPPHMIQA
Kinase LmjF03.0210.AA p38 15-238 33 3.8e-40 134.75 In-house 1-227 (289) Show / Hide 
Range on Protein: 15-238
Range on HMM: 1-227/289
Sequence Identity: 33% (79 aa)

FQVESIIGQGAYGAVCKAVF--CNDQ---IAVKKIPHYSRSEDTARRVLREIEILQNLQFCEQVVGCRLFFRP----KSEEKDVYVAMDYIPADLSSVIK
.|  . .|.||||.||||.    ...   .|.||.     ||  |.|  ||.  |. ..  | |..    | |     .. .|||. .    |||. ..|
YQNLQPVGSGAYGQVCKAEDRRTGQKRRYVAIKKLMRPFQSEIHAKRTYRELRLLKHMRH-ENVICLLDVFTPPAHSMNDFQDVYMVTHFMGADLNNIMK

NGAITLDESVVRYITCQLLLALRALHRCKVLHRDVSTRNILIHYNSQVFLCDFGLSRFFDPDEQLSFGVVTQWYRAPEIILD-AAYSYASDVWSVGVILG
  .  | .  ....  |.| .|.  |   . |||    || .  .. .   ||||.|    |. .   |.| |||||||.|    |  . |.|||| |. 
CQR--LSDDHIQFLVYQILRGLKYIHSAGIIHRDLKPSNIAVNEDCELRILDFGLAR--HCDDEMTGYVATRWYRAPEIMLNWMHYTQTVDIWSVGCIMA

ELLLRRHLFPGKSNDSANQLQLIFHLVGTPSKDV
||. .| ||||.  |  .||| |  ..|||.. .
ELITGRTLFPGD--DHIDQLQRIMKVCGTPDEEF
Kinase LmjF03.0210.AA PITSLRE 89-235 34 1.3e-33 118.0 In-house 78-227 (295) Show / Hide 
Range on Protein: 89-235
Range on HMM: 78-227/295
Sequence Identity: 34% (53 aa)

VYVAMDYIPADLSSVIKNGA---ITLDESVVRYITCQLLLALRALHRCKVLHRDVSTRNILIHYNSQVFLCDFGLSRFFDPD-EQLSFGVVTQWYRAPEI
.| .|.|.  || |.. |         .. .   . |||..   .|  ...|||  | |.|.  . .  .||||| | .    . .. .||| ||||||.
IYMVMEYVEHDLKSLMENMKRRNQPFKPGEIKCLMQQLLRGVEHMHDNWIMHRDLKTSNLLYSHKGILKICDFGLAREYGSPIKPYTPCVVTLWYRAPEL

ILDAA-YSYASDVWSVGVILGELLLRRHLFPGKSNDSANQLQLIFHLVGTPS
 |..  || . |.|||| |..|... . ||.|||    .|.. || . |||.
LLGCKKYSTPVDMWSVGCIFAEFITMKPLFQGKSE--IDQINCIFKEMGTPT
Kinase LmjF03.0210.AA MAPK-Unclassified 15-164 31 6.7e-28 97.67 In-house 1-170 (575) Show / Hide 
Range on Protein: 15-164
Range on HMM: 1-170/575
Sequence Identity: 31% (55 aa)

FQVESIIGQGAYGAVCKAVFCND---QIAVKKIPHYSRSEDTARRVLREIEILQNLQFCEQVVGCRLFFRPKSEEK----DVYVAMDYIPA---DLSSVI
  ..  ||.|||| ||.|.       | | ||..| .  . ...|||||| ||  |   . ..  .  |..|. .     |.|. ||| .    || ..|
YEYQKNIGSGAYGQVCRAMDKKNQNQQVAIKKVNHIFHNHTDCKRVLREIRILRYLNH-PNIIQIQDIFYNKELHNQEFDDIYIVMDYMQTSLFDLHQII

KNGAI-TLDESVVRYITCQLLLALRALHRCKVLHRDVSTRNILIHYNSQVFLCDFGLSR-----------FF
| . . .. .  ..|.. |.|  |  ||   ..|||    |.||  .  |  ||||.||           ||
K-SNQDHWCHQHIQYFFYQILRGLKYLHSACIIHRDLKPSNLLINQDCSVRICDFGMSRSIEDNQNLRFSFF
Kinase LmjF03.0210.AA MAPK-Unclassified 174-240 30 3.9e-20 69.1 In-house 409-505 (575) Show / Hide 
Range on Protein: 174-240
Range on HMM: 409-505/575
Sequence Identity: 30% (30 aa)

VVTQWYRAPEIIL-DAAYSYASDVWSVGVILGELLLR-----------RHLFPGKS---------NDSA---------NQLQLIFHLVGTPSKDVFD
||| |||||||.|    |. ..| ||.| |..|....           | ||||..         ||.           |...||   |.| . . .
VVTRWYRAPEIMLSMHEYDTQVDIWSIGCIFAEMMQMYDRHNPTFSDHRPLFPGQDCFPITPDRNNDVDQGGFPHSHQDQIKMIFDYLGMPPEEDCN
Kinase LmjF03.0210.AA TyrKc 15-318 20 4.9e-14 4.32 SMART 1-280 (280) Show / Hide 
Range on Protein: 15-318
Range on HMM: 1-280/280
Sequence Identity: 20% (67 aa)

FQVESIIGQGAYGAVCKAVFCNDQIAVKKIPHYSRSEDTARRVLREIEILQNL-QFCEQVVGCRLFFRPKSEE----KDVYVAMDYIPA-DLSSVIKNGA
 . . ..| ||.| |.|..    | |||.. ...      .  .||..|. .|    . .| .    . ...     . ... | | |  || . ...  
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

ITLDESVVRYITCQLLLALRALHRCKVLHRDVSTRNILIHYNSQVFLCDFGLSRFFDPD-------EQLSFGV--VTQ------WYRAPEIILDAAYSYA
 .|  .   ..  |     . ||. .. |||  .||.|.. | .|  .||||||. . |       .  .      .       |. ||| | .  .. .
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM-APECINYGKFTTK

SDVWSVGVILGELL-LRRHLFPG-----KSNDSANQLQLIFHLVGTPSK----DVFDADRSFGRASQNARNYALAYIERRPCPSTLVNLLSTAPALHHSA
||||| || . |.. .     ||     .||. . ..    .    |                                                   . 
SDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS--------------------------------------------F-

IAAVPPQVVQLAEQLLQFDPARRPSADEALRHPWF
    |. . |. .|  ..||. ||.  |   |  |
-VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF03.0210.AA Pkinase_Tyr 130-198 34 2.4e-10 35.67 Pfam 127-199 (270) Show / Hide 
Range on Protein: 130-198
Range on HMM: 127-199/270
Sequence Identity: 34% (26 aa)

LHRCKVLHRDVSTRNILIHYNSQVFLCDFGLSRFFDPDEQLSFGVVTQ-------WYRAPEIILDAAYSYASDVWS
|.. .  |||. .||.|.. | .|  |||||.|   .|..  . ....       |. ||| | .  .. .|||||
LESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-Y-RKRGGGKLPIKWM-APECINYGKFTTKSDVWS
Kinase LmjF03.0210.AA p38 289-318 46 2.6e-09 27.7 In-house 260-289 (289) Show / Hide 
Range on Protein: 289-318
Range on HMM: 260-289/289
Sequence Identity: 46% (14 aa)

PQVVQLAEQLLQFDPARRPSADEALRHPWF
|| . | | .|. || .| .| ||..||.|
PQAIDLLEKMLELDPDKRITAEEAMQHPYF
Kinase LmjF03.0210.AA PITSLRE 297-318 50 3.3e-08 26.2 In-house 274-295 (295) Show / Hide 
Range on Protein: 297-318
Range on HMM: 274-295/295
Sequence Identity: 50% (11 aa)

QLLQFDPARRPSADEALRHPWF
|.| ..|..| .|..|| ||||
QMLTYNPKNRITASDALKHPWF
Kinase LmjF03.0210.AA MAPK-Unclassified 285-318 30 5.4e-08 24.45 In-house 533-575 (575) Show / Hide 
Range on Protein: 285-318
Range on HMM: 533-575/575
Sequence Identity: 30% (13 aa)

AAVP---------PQVVQLAEQLLQFDPARRPSADEALRHPWF
...|         ..   .  ..|||.| .| .||.|| || |
CKAPGDDQIVRGNCECIDFVQKMLQFNPWKRITADQALEHPYF
Kinase LmjF03.0210.AA ERK7 292-318 40 6e-06 15.92 In-house 266-292 (292) Show / Hide 
Range on Protein: 292-318
Range on HMM: 266-292/292
Sequence Identity: 40% (11 aa)

VQLAEQLLQFDPARRPSADEALRHPWF
. |  .||.| | .| .|..||.||. 
IDLLKRLLVFNPKKRLTAEQALQHPYV
Kinase LmjF03.0210.AA ERK5 289-318 33 1.4e-05 16.33 In-house 266-295 (295) Show / Hide 
Range on Protein: 289-318
Range on HMM: 266-295/295
Sequence Identity: 33% (10 aa)

PQVVQLAEQLLQFDPARRPSADEALRHPWF
.| ..|  ..| |.|. | .. .||.||. 
RQALDLLARMLRFEPSERITVNKALQHPFL
Kinase LmjF03.0210.AA Pkinase_Tyr 15-68 22 0.000846 13.49 Pfam 1-62 (270) Show / Hide 
Range on Protein: 15-68
Range on HMM: 1-62/270
Sequence Identity: 22% (14 aa)

FQVESIIGQGAYGAVCKAVFC------NDQIAVKKIPHYSRSED-TARRVLREIEILQNL-Q
 .    .|.||.| |.|..        . . |||...... .|.   .  .||..|. .| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGH