Gene LmjF15.0180 (L.major)

LmjF15.0180

Species: L.major
Alias: LmjF15.0180, LmajK069
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK1

Sequence

Name Sequence Type Origin Length Description Download
LmjF15.0180.AA Protein None 521 None Fasta, JSON
LmjF15.0180.kin_dom Protein Kinase Domain None 313 None Fasta, JSON

Protein domain

Protein domains of LmjF15.0180.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF15.0180.AA DYRK 136-448 39 3.6e-124 418.83 In-house 1-320 (320) Show / Hide 
Range on Protein: 136-448
Range on HMM: 1-320/320
Sequence Identity: 39% (130 aa)

YIAQEVLGKGSFGTVIRGFDQKRSEAVAMKITRRGSSFRSQAKLELDILLRLNEN-PALNHLVVRLLKVFEWQGHLVLVFELLSFNLYQLIKCTRFNGV-
|   |..|||||| |....|.|. | ||.|| |.  .|  ||. |. || .||.. |  .. .|...  | ...|| .|||||| |||...| ..|.|. 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

SLDLVRKFAYQLTHTLLQLELQKPHPIIHCDLKPENILLRNQ-NRSGIRLIDFGSACYTAKRFHRYIQSRFYRSPEVILFLDYGTPIDRWSLACVLVEMH
|| ||||||.|. . |. |.      |||||||||||.|... |.|.| .|||||.|. ..|...||||||||.||||| . |...|| ||| |.|.|..
SLNLVRKFAQQILTCLKFLHKNE--NIIHCDLKPENIMLKQPRNKSTIKVIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELF

TGVPLFDGRTEAAQLAKIEATLGPIPAGMVAGS--PKANRFYYGNATSGFQLKEPIPERRT---------LESVIGVTTGGPRGRRLHTPGHDETAYREF
|| ||| | .|  |||.|  .||..|  |.  .  .....|.       .. ..  .....         .    . ....| |||   |.|. . ...|
TGWPLFPGENEYDQLACIMEVLGMPPKWMIDKGRCRRKHKFFDC---FMYCECDEWTKQNKITDHYMTPKCHPTKR-GQRRPPGRRNWDPRHQ-CDDHQF

HDFVSRFLRYEPEERMNCRDALQHPFL
 ||. . | ..|..|. . .|||||..
KDFIKKCLQWDPHKRITPSQALQHPWF
Kinase LmjF15.0180.AA DYRK1 136-448 44 9.3e-115 387.55 In-house 1-321 (321) Show / Hide 
Range on Protein: 136-448
Range on HMM: 1-321/321
Sequence Identity: 44% (143 aa)

YIAQEVLGKGSFGTVIRGFDQKRSEAVAMKITRRGSSFRSQAKLELDIL-LRLNENPALNHLVVRLLKVFEWQGHLVLVFELLSFNLYQLIKCTRFNGVS
|  .  .|||||| |.. .|... | ||.|| .   .|  ||..|. .| |  .. .     .|.| . | .  || |||||||.||| |.. | | |||
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEIRLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS

LDLVRKFAYQLTHTLLQLELQKPHPIIHCDLKPENILLRNQNRSGIRLIDFGSACYTAKRFHRYIQSRFYRSPEVILFLDYGTPIDRWSLACVLVEMHTG
| |.|||| |.  .|| .     . |||||||||||||.|  || |..|||||.| . .|  .||||||||||||.| ..| . || ||| |.|||||||
LNLTRKFAQQMCTALLFMSTPELD-IIHCDLKPENILLCNPKRSAIKIIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTG

VPLFDGRTEAAQLAKIEATLGPIPAGMVAGSPKANRFYYGNATSGFQLKEPIPERR--------TLESVIGVTTGGPRGRRLHTPGHDETAYREFHDFVS
 ||| |  |  |. ||   ||  |. |.  .||| ...  .   ....|    ...         |. ..||.|||| |||.  |||  . |  |.| . 
EPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKYFEKDPDNTWYCKKTRDKKKHYKEPCTRKLHEILGVETGGPGGRRKGEPGHSVEDYLKFKDLIK

RFLRYEPEERMNCRDALQHPFL
| |.|.|..|..  .||||.|.
RMLQYDPKQRITPYYALQHSFF
Kinase LmjF15.0180.AA DYRK2 136-350 47 2.3e-94 307.3 In-house 1-214 (318) Show / Hide 
Range on Protein: 136-350
Range on HMM: 1-214/318
Sequence Identity: 47% (102 aa)

YIAQEVLGKGSFGTVIRGFDQKRSEAVAMKITRRGSSFRSQAKLELDILLRLNE-NPALNHLVVRLLKVFEWQGHLVLVFELLSFNLYQLIKCTRFNGVS
|   ||.|||||| |....| |. . || |. |  . | .||  |. || .. . ..  .. .|..|  |   .|. ..||||| ||| .||   |.| |
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

LDLVRKFAYQLTHTLLQLELQKPHPIIHCDLKPENILLRNQNRSGIRLIDFGSACYTAK-RFHRYIQSRFYRSPEVILFLDYGTPIDRWSLACVLVEMHT
| |||.||... . |  |   .   |||||||||||||. .||||| .||||| |.    |...||||||||.||||| . ||..|| ||. |...|. |
LQLVRRFAHSILQCLRFLHKNN---IIHCDLKPENILLKQWNRSGIKVIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYT

GVPLFDGRTEAAQLAKI
|.||| |  |. |.| .
GYPLFPGENENDQFACM
Kinase LmjF15.0180.AA CMGC 136-448 19 1.6e-82 270.81 In-house 1-513 (513) Show / Hide 
Range on Protein: 136-448
Range on HMM: 1-513/513
Sequence Identity: 19% (100 aa)

YIAQEVLGKGSFGTVIRGFDQKRS--------------EAVAMKITRRGSSFRSQAK-------------LELDILLRLNE----------NPALNHL--
|   ...|.|..|.| ...|...               | ||.|. ..   .  |||              |. || .||.          .|  .|   
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

VVRLLKVFEWQG-----------------HLVLVFELLSFNLYQLIKCTR--FNG------------------------VSLDLVRKFAYQLTHTLLQLE
.|.|. .|   .                 || ||||..  .|||.|| ..  ..|                         .. ..| ..||.   |    
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSEHENKHPHRRPPHNIKYFMI-HIR-YMYQILRGLKLKY

LQKPH-PIIHCDLKPENILLRNQNRS------------------GIRLIDFGSACYTAKR------------------------FHRYIQSRFYRSPEVI
. .    |||.||||||||. .....                   ....|||.|... ..                        .  |...|.||.||..
CHSHWGNIIHRDLKPENILINHNCELITRMMWKSEDWNPCQKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEIL

LFLD----------YGTPIDRWSLACVLVEMHTG--------VPLFDGRTE-----------AAQLAKIEATLGPIPAGMVAG-------SPKANRFYYG
|             |.|||| ||..|.. || ||         ||| |..|             ||.||  .||...  |          ... . ... 
LGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLIFRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFKVLGTPT-WMIQKGKRHFNFCKHEEEWPNM

NATSGFQLKE------------PIPERRTLESVIGVTTGGPRGRRLHTPGHDE-------------------------------TAYREFHDFVSRFLRY
.   .....             ..  |. ..| .   .  |.  .   |.|..                                .  .. |.... |.|
IKLPWYNKFPKKWNWQTMTNHWSEFARNYIQSNNRFPWWPPKPWKNLFPWHPNWDDNNKKAMVFNWIYEEKFKSHKFNHQFKRKCCDPQAIDLLKKMLQY

EPEERMNCRDALQHPFL
.|..|. . .|||||..
DPDKRITAEQALQHPYF
Kinase LmjF15.0180.AA YAK 136-362 39 6.5e-66 222.8 In-house 1-229 (347) Show / Hide 
Range on Protein: 136-362
Range on HMM: 1-229/347
Sequence Identity: 39% (92 aa)

YIAQEVLGKGSFGTVIRGFDQKRSEAVAMKITRRGSSFRSQAKLELDILLRLN--ENPALNH---LVVRLLKVFEWQGHLVLVFELLSFNLYQLIKCTRF
||   .||.| || |.        | .| |.      .  |||.|  ||  ||  . |   .    ..|..  | .  |. ||||.|| ||| ..| ..|
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF

NGVSLDLVRKFAYQLTHTLLQLELQKPHPIIHCDLKPENILLRNQNRSGIRLIDFGSACYTAKRFHRYIQSRFYRSPEVILFLDYGTPIDRWSLACVLVE
 | |  |.| .  |    .  ||  .   |||||||||||.|.. |.  |..|||||.|...|    |||.|.|||||.|.   | | || ||| |...|
CGFSFQLIRQWTKQILDGMCVLENKQ---IIHCDLKPENIMLCKPNKPEIKIIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAE

MHTGVPLFDGRTEAAQLAKIEATLGPIPAGMV
   |.|.| |  |  |.  |  .||  |  |.
LFLGLPIFPGNSEYNQIKRIIDMLGYPPSWMI
Kinase LmjF15.0180.AA S_TKc 136-448 23 1.7e-61 211.56 SMART 1-231 (231) Show / Hide 
Range on Protein: 136-448
Range on HMM: 1-231/231
Sequence Identity: 23% (78 aa)

YIAQEVLGKGSFGTVIRGFDQKRSEAVAMKITRRGSSFRSQAKLELDILLRLNENPALNHLVVRLLKVFEWQGHLVLVFELLSF---NLYQLIKCTRFNG
|   ...|||.||.| .. . |  . ||.|| .       ... |..|| .          .|.|. ||.  .|| .|.|...    .|...||  . .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK------HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHG

----VSLDLVRKFAYQLTHTLLQLELQKPHPIIHCDLKPENILLRNQNRSGIRLIDFGSACYTAKRFHRYIQSRFYRSPEVILFLDYGT-PIDRWSLACV
     .   .|...||.   |  .  ..   |||.||||||||| .     | ..|||.|.      . .. ...|..|||.    ||. ..| ||. |.
LRFPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE----HIKICDFGLARQL----TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LVEMHTGVPLFDGRTEAAQLAKIEATLGPIPAGMVAGSPKANRFYYGNATSGFQLKEPIPERRTLESVIGVTTGGPRGRRLHTPGHDETAYREFHDFVSR
| || .| |.|.  .... . ||                                                                    .|. ||...
LYEMLCGYPPFP--QMQMMFKKIG------------------------------------------------------------------SPEAKDFIRK

FLRYEPEERMNCRDALQ-------HPFL
 |...||.|. . .|||       ||..
CLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF15.0180.AA HIPK 136-382 35 7.3e-57 177.39 In-house 1-247 (329) Show / Hide 
Range on Protein: 136-382
Range on HMM: 1-247/329
Sequence Identity: 35% (89 aa)

YIAQEVLGKGSFGTVIRGFDQKRSEAVAMKITRRGSSFRSQAKLELDILLRLNENPALNHLVVRLLKVFEWQGHLVLVFELLSFNLYQLIKCTRFNGVSL
|   |.||.| || |...  .  .| ||.|| ..  ..  | . |. || .| .  | .  .|| . .|. . |  ||||.|  |||.  |  .|    |
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLPL

DLVRKFAYQLTHTLLQLELQKPHPIIHCDLKPENILLRNQNRSGIR--LIDFGSACYTAKRFHR-YIQSRFYRSPEVILFLDYGTPIDRWSLACVLVEMH
  .|    |    |..|   |   .|| |||||||.|  . |   |   |||||| .  |     |.|||.|| ||.|| | .   .| ||| ||. | .
KHIRPILQQVLTALMKL---KELGLIHADLKPENIMLVDPTRCPYRVKVIDFGSASHVSKVVCNTYLQSRYYRAPEIILGLPFCENHDMWSLGCVIAELF

TGVPLFDGRTEAAQLAKIEATLGPIPAGMVAGSPKANRFYYGNATSGFQL
 | ||..|  |  |   |. | .     ..    |..||.     |.|..
LGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKKHRFFDRDKQSKFRP
Kinase LmjF15.0180.AA PRP4 136-342 36 1.5e-45 157.64 In-house 1-209 (320) Show / Hide 
Range on Protein: 136-342
Range on HMM: 1-209/320
Sequence Identity: 36% (78 aa)

YIAQEVLGKGSFGTVIRGFDQKRSE-AVAMKITRRGSSFRSQAKLELDILLRLNEN---PALNHLVVRLLKVFEWQGHLVLVFELLSFNLYQLIKC-TRF
|      |.| |..|.|. || |    || || |   . .     || || .||..   .     .||.  .|... |. |||| .| || ...|   . 
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

NGVSLDLVRKFAYQLTHTLLQLELQKPHPIIHCDLKPENILLRNQNRSGIRLIDFGSACYTAKR-FHRYIQSRFYRSPEVILFLDYGTPIDRWSLACVLV
 | .|. || .|.||   .| | . |   |.| |.|| |||  | ... . ..|||||   .      | .|||||.||.|.   |   || || .| | 
VGLHLKAVRSYAQQL---FLALKHLKKCNILHADIKPDNILV-NESKNTLKMCDFGSASHIHENEITPYLVSRFYRAPEIIIGHPYDYQIDMWSVGCTLY

EMHTGVPLFDGRT
|. ||  .|.|.|
ELYTGKIMFPGKT
Kinase LmjF15.0180.AA DyrkP 136-362 34 2.7e-37 119.94 In-house 1-229 (323) Show / Hide 
Range on Protein: 136-362
Range on HMM: 1-229/323
Sequence Identity: 34% (79 aa)

YIAQEVLGKGSFGTVIRGFDQKRSEAVAMKITRRGSSFRSQAKLELDILLRLNENPALNHL-VVRLLKVFEWQGHLVLVFELLSFNLYQLIKCTRFNG--
|   | ||   |   |   |..    . |||      .  |.  |. .|  .| |       |.|    |  . || .. |||  |||   |  | |   
YQIMEYLGSAAFSKAIQCQDKQTNQMMCMKIIENNKDYFDQSIDEIKLLRYINYNGDVDEKNVLRYYDYFYHKEHLFIITELLKDNLYEFYKFNRENEQQ

--VSLDLVRKFAYQLTHTLLQLELQKPHPIIHCDLKPENILLRNQNRSGIRLIDFGSACYTAKRFHRYIQSRFYRSPEVILFLDYGTPIDRWSLACVLVE
    .  . |   |.   |. |.      .|||||||||||.. . .  ...|||||.|.       |.||| || ||||.   |   || ||| |.| |
RYFTVGRLQKITQQI---LIALDYIHSLRLIHCDLKPENILMKSYPKCQVKIIDFGSSCFIHDHLSSYVQSRSYRAPEVIIGCKYDYRIDMWSLGCILAE

MHTGVPLFDGRTEAAQLAKIEATLGPIPAGMV
. ||  ||   .    ||..   .||.|  |.
LWTGNVLFQNDNIQGLLARVIGIIGPFPEWMM
Kinase LmjF15.0180.AA CLK 136-272 30 2.7e-33 96.64 In-house 1-147 (350) Show / Hide 
Range on Protein: 136-272
Range on HMM: 1-147/350
Sequence Identity: 30% (46 aa)

YIAQEVLGKGSFGTVIRGFDQKRS-EAVAMKITRRGSSFRSQAKLELD-ILLRLNEN--PALNHL--VVRLLKVFEW-QGHLVLVFELLSFNLYQLIKCT
|    .|| | ||.| .  | |..   || || |  . .| .|..|.. |.  .||.  | . ..  .....  |.   ||  .||||.  ..| ..| .
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

R------FNGVSLDLVRKFAYQLTHTLLQLELQKPHPIIHCDLKPENILL
.      . .  .| .|..|||| . .  |.  |   ..| |||||||..
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMK---LTHTDLKPENICF
Kinase LmjF15.0180.AA Pkinase 258-448 25 6.7e-31 110.34 Pfam 127-293 (293) Show / Hide 
Range on Protein: 258-448
Range on HMM: 127-293/293
Sequence Identity: 25% (52 aa)

HPIIHCDLKPENILLRNQNRSGI----RLIDFGSAC---YTAKRFHRYIQSRFYRSPEVIL-FLDYGTPIDRWSLACVLVEMHTGVPLFDGR----TEAA
. |||.||||||||.   |.  |    ...|||.|.   |    .. .  ...|..||||.   .||...| ||. |.| || .| |.|.|.    . . 
MGIIHRDLKPENILID--NNGHIDACVKICDFGLAKQFDYNNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-HD

QLAKIEATLGPIPAGMVAGS---PKANRFYYGNATSGFQLKEPIPERRTLESVIGVTTGGPRGRRLHTPGHDETAYREFHDFVSRFLRYEPEERMNCRDA
|...|. ..||..      .   .  . |..   .                             . |..  ...  .|. ||... |.. |..| .....
QMQMICRIMGPPLHFDWPWWCSISYFF-FRH-W-H-----------------------------F-HWTF-HNWS-EECKDFIKWCLCKDPKKRPTAEQI

LQHPFL
||||..
LQHPWF
Kinase LmjF15.0180.AA CDK 197-355 27 7e-22 66.64 In-house 69-242 (284) Show / Hide 
Range on Protein: 197-355
Range on HMM: 69-242/284
Sequence Identity: 27% (51 aa)

VVRLLKVFEWQ-----------GHLVLVFELLSFNLYQLIKCTRFNGVSLDLVRKFAYQLTHTLLQLELQKPHPIIHCDLKPENILLRNQN---RSGIRL
.|.|. |.                |..||| .   |.....           .. . .||   |  .  ..   |.| |||| |||. |.    .  . .
IVKLHDVCHTKNMDRNNKDKHENKLYMVFEYMDHDLKKYMD-----------IKCYMWQLLRGLHYCHSNW---IMHRDLKPQNILINNNGEVKCGRLKI

IDFGSACYTA---------KRFHRYIQSRFYRSPEVIL-FLDYG--TPIDRWSLACVLVEMHT---GVPLFDGRTEAAQLAKIEATLG
 ||| |.            . .   .  . ||.||. |   .|.  |||| ||. |...|| |   . ||| |..|  || ||  ..|
ADFGLARAFGIPHQMSEPNRTYTHEVVTLWYRAPELLLGSKHYSGGTPIDMWSVGCIFAEMFTDVTRKPLFPGDSEIDQLFKIFRICG
Kinase LmjF15.0180.AA CLK 280-361 40 4.6e-18 50.08 In-house 186-271 (350) Show / Hide 
Range on Protein: 280-361
Range on HMM: 186-271/350
Sequence Identity: 40% (35 aa)

IRLIDFGSAC---YTAKRFHRYIQSRFYRSPEVILFLDYGTPIDRWSLACVLVEMHTGVPLFDGRTEAAQLAKIEATLG-PIPAGM
|..||||||    .        ...| || ||||| | . .| | || .|.|.|  ||. ||..  .   || .|  .| |||  |
ICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQTHDNREHLAMMERIMGMPIPQWM
Kinase LmjF15.0180.AA Pkinase 136-245 25 8.5e-10 35.72 Pfam 1-117 (293) Show / Hide 
Range on Protein: 136-245
Range on HMM: 1-117/293
Sequence Identity: 25% (31 aa)

YIAQEVLGKGSFGTVIRGFDQKRSEAVAMKITRRGSSFRSQAKL-----ELDILLRLNENPALNHLVVRLLKVFEWQGHLVLVFELLSF-----NLYQLI
|   ...|.||||.| .. ... .. ||.|| .. .   .. .      |. |..|||     |  .|||. .||  .|. .|.|..        |. .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN---HPN--IVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYI

K---CTRFNGVSLDLVRKFAYQL
.    ..|   | . .....||.
STWRHGCFY-FSEWECKFYMYQI
Kinase LmjF15.0180.AA CLK 419-448 46 1.7e-09 23.91 In-house 321-350 (350) Show / Hide 
Range on Protein: 419-448
Range on HMM: 321-350/350
Sequence Identity: 46% (14 aa)

REFHDFVSRFLRYEPEERMNCRDALQHPFL
|.. | ... | |.|  |. |.||||||| 
RQLFDLIRKMLEYDPSKRITCKDALQHPFF
Kinase LmjF15.0180.AA CDK 423-448 38 4.7e-09 24.94 In-house 259-284 (284) Show / Hide 
Range on Protein: 423-448
Range on HMM: 259-284/284
Sequence Identity: 38% (10 aa)

DFVSRFLRYEPEERMNCRDALQHPFL
|. ...| |.|. |... .|||||..
DLLNKMLCYDPKKRISAEQALQHPYF
Kinase LmjF15.0180.AA DYRK2 421-448 42 4.9e-09 25.18 In-house 291-318 (318) Show / Hide 
Range on Protein: 421-448
Range on HMM: 291-318/318
Sequence Identity: 42% (12 aa)

FHDFVSRFLRYEPEERMNCRDALQHPFL
| ||..| .  .|.|||  ..||.||..
FIDFIKRCFEWDPSERMTPSQALKHPWI
Kinase LmjF15.0180.AA TyrKc 136-448 15 1.3e-07 -99.56 SMART 1-280 (280) Show / Hide 
Range on Protein: 136-448
Range on HMM: 1-280/280
Sequence Identity: 15% (54 aa)

YIAQEVLGKGSFGTVIRGFDQKRSEAVAMKITRRGSSFRSQAKLELDILLRLNENPALNHL------VVRLLKVFEWQ-------GHLVLVFELLSF-NL
    ..|| | ||.| .|      . || |  . ..           .   ..|   . .|      .|||. |   |       . | .|.|. .  .|
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDL

YQLIKCTRFNGVSLDLVRKFAYQLTHTLLQLELQKPHPIIHCDLKPENILLRNQNRSGIRLIDFGSACYTAKR-----FHRYI------QSR-----FYR
 . .. .| . ....   .|..|       |. .   ..|| ||   |.|. ...   ..  ||| . .          . |.      ...        
KDYLRKHRPK-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENH--TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWM

SPEVILFLDYGTPIDRWSLACVLVEMHT-GVPLFDG-------RTEAAQLAKIEATLGPIPA----GMVAGSPKANRFYYGNATSGFQLKEPIPERRTLE
.||.| .  . |  | ||   .. |. | | .   |        .|. .. |    . . |                                       
APECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---------------------------------

SVIGVTTGGPRGRRLHTPGHDETAYREFHDFVSRFLRYEPEERMNCRDALQHPFL
                      ..  | ..  ..  ...||.| . ..   | ..
-------------------F-VCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF15.0180.AA CDK 136-168 28 2e-06 16.64 In-house 1-38 (284) Show / Hide 
Range on Protein: 136-168
Range on HMM: 1-38/284
Sequence Identity: 28% (11 aa)

YIAQEVLGKGSFGTVIRGFDQKRS-----EAVAMKITR
|   | .| |..|.| .. |...      . ||.|  |
YEKLEKIGEGTYGVVYKARDKQTGRKKTGQIVALKKIR
Kinase LmjF15.0180.AA PRP4 421-448 39 3.5e-05 14.99 In-house 293-320 (320) Show / Hide 
Range on Protein: 421-448
Range on HMM: 293-320/320
Sequence Identity: 39% (11 aa)

FHDFVSRFLRYEPEERMNCRDALQHPFL
| |.  . |   |. |  | .||.|||.
FKDLLDKCLMLDPKKRITCNEALKHPFI
Kinase LmjF15.0180.AA YAK 421-448 42 3.7e-05 13.03 In-house 320-347 (347) Show / Hide 
Range on Protein: 421-448
Range on HMM: 320-347/347
Sequence Identity: 42% (12 aa)

FHDFVSRFLRYEPEERMNCRDALQHPFL
| ||.   |  .| ||     | ||||.
FIDFINQLLQLNPRERWKPMQAMQHPFI
Kinase LmjF15.0180.AA HIPK 418-448 29 0.000475 8.1 In-house 299-329 (329) Show / Hide 
Range on Protein: 418-448
Range on HMM: 299-329/329
Sequence Identity: 29% (9 aa)

YREFHDFVSRFLRYEPEERMNCRDALQHPFL
.||| .   . .  ....|.   .||.||| 
RREFVHVLKKMCTWDAHKRITPCEALNHPFV
Kinase LmjF15.0180.AA DyrkP 421-448 39 0.00067 7.97 In-house 296-323 (323) Show / Hide 
Range on Protein: 421-448
Range on HMM: 296-323/323
Sequence Identity: 39% (11 aa)

FHDFVSRFLRYEPEERMNCRDALQHPFL
| ||| . |  .   |   ..|||||..
FIDFVRQCLQIDFTRRPTAKEALQHPWF