LmjF36.4250

Species: L.major
Alias: LmajK066, LmjF36.4250
External Links:
Annotation:

Classification

Group: CMGC
Family: DYRK
Subfamily: DYRK-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF36.4250.AA Protein None 807 None Fasta, JSON
LmjF36.4250.kin_dom Protein Kinase Domain None 518 None Fasta, JSON

Protein domain

Protein domains of LmjF36.4250.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF36.4250.AA CMGC 16-398 15 9.7e-70 228.05 In-house 1-368 (513) Show / Hide
Range on Protein: 16-398
Range on HMM: 1-368/513
Sequence Identity: 15% (82 aa)

YIPNKVLGTGTYGQVIRCYD--------------NVTGKDVAVKVAQSDAAYRRSAL-------------NEISALLCLK---------------ENED-
|   |..| ||||.| .|.|              . |.. ||.|   ..  | . |.              ||. | .|.               ...  
YEIIKKIGEGTYGVVYKCRDKRTNQKKDNGQAHHHETNEIVAIKKIKNPF-YEEQAKSTIEKDGFPIRALREIKILKHLNKNHDPNWQRRDDPDNKHHNN

SVNILDSFEDAG-----------------HVCIVSELLDRNLFEVLRHRGFG-------PLSLRE------------VRQVA------LRVLSALA--SL
 |...|.| . .                 |...| |..| .|......  |        |||  .            ..           .| .|.   .
IVKLYDIFYHKNSDGNEYEDKHIISQHFNHLYLVFEYMDHDLYQYIKNNQFDYQGKRPMPLSE-HENKHPHRRPPHNIKYFMIHIRYMYQILRGLKLKYC

HNSG--YIHCDIKPENIMLRRSTPV-------SSDSSSFMLGPFTSENASSGSSNKSGEQNNFPNALAPGQAALKLDSNANAHNQLWRNTNSIDSLVGNT
|  .   ||.|.|||||..   . .       |.                                                                  
HSHWGNIIHRDLKPENILINHNCELITRMMWKSE------------------------------------------------------------------

HSAAFQDSDLNMGFSPRTGNRLGGYSKQQHGQRGSGDATAAISGAGMRYSSSLDALFSMPAAAVGASGTGNSTRNDLRVNCNALGNKGIESQERTQFNPD
                                                                                             .   ||.
---------------------------------------------------------------------------------------------D-W-NPC

ANPYRRTCLIDFGAVRRFNEN------------------------TYYDVQSLWYRAPEVLCGLP----------YTTAIDSWSVGCVLFELFTG-----
 .   |  ..|||  | ....                         . .|...||||||.|.| .          |||.|| |||||...|..||     
-QKNGRLKICDFGLARWYHPHSDHHFQQQPQSFKNVNKDDKPNRPYTHYVVTRWYRAPEILLGWKHYTNHNYSMHYTTPIDMWSVGCIFAEMYTGYQSLI

---KPFFPGESL-----------QHQLSLIVQ
   ||.|||.|            ..|| .|..
FRGKPLFPGHSEYPNDDKNGKSHIDQLFKIFK

Kinase LmjF36.4250.AA S_TKc 16-533 13 1.9e-57 198.09 SMART 1-231 (231) Show / Hide
Range on Protein: 16-533
Range on HMM: 1-231/231
Sequence Identity: 13% (70 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCLKENEDSVNILDSFEDAGHVCIVSELLDR---NLFEVLRHRGFGP----
|   ...| |..|.| .|... ||. ||.|.        .....||. |      .  |...|.|.| .|...| |..|    .||.....|| ..    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK--HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LSLREVRQVALRVLSALASLHNSGYIHCDIKPENIMLRRSTPVSSD--SSSFMLGPFTSENASSGSSNKSGEQNNFPNALAPGQAALKLDSNANAHNQLW
..  ..| ..  ...||. .|. | ||.|.|||||.| . .   .|  .. ..                                               
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE-HIKICDFGLARQL-----------------------------------------------

RNTNSIDSLVGNTHSAAFQDSDLNMGFSPRTGNRLGGYSKQQHGQRGSGDATAAISGAGMRYSSSLDALFSMPAAAVGASGTGNSTRNDLRVNCNALGNK
                                                                                                    
----------------------------------------------------------------------------------------------------

GIESQERTQFNPDANPYRRTCLIDFGAVRRFNENTYYDVQSLWYRAPEVLCGLPYTT-AIDSWSVGCVLFELFTGKPFFPGESLQHQLSLIVQHVGHPSQ
                                   .  . ..||.|||||   .|.. ..| ||.||.|.|...|.| ||      |. .. ...|    
-----------------------------------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP------QMQMMFKKIG----

AALTLGCLATQFQLPMVYVSHDARREHVRQWILSSREAGLQRWRKHQIQKLQEAHIAGNQQLWLHRTADVPNTKSEEDALLTATPYGESDVDGASEELEL
                                                                                                  . 
-------------------------------------------------------------------------------------------------SPE

LVDLVCDLLNPDESQRLSCTQALR-------HPFL
. |... .|. | ..|... .||.       ||..
AKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase LmjF36.4250.AA CLK 16-386 19 1.4e-45 134.22 In-house 1-249 (350) Show / Hide
Range on Protein: 16-386
Range on HMM: 1-249/350
Sequence Identity: 19% (77 aa)

YIPNKVLGTGTYGQVIRCYDNVTGK-DVAVKVAQSDAAYRRSALNEIS-ALLCLKEN--------EDSVNILDSFED-AGHVCIVSELLDRNLFEVLRHR
|   ..|| || | | .| |.  ||  ||.|.  .   ||  |  ||.  .  ..|.        |... ..|.|.   ||.||| ||. ........  
YEIVCTLGEGTFGKVVECWDHKNGKKYVALKIIRNVEKYREAAWVEINQIMKKINEKHDPNNKYWEHCWKMNDWFDYGHGHICIVFELYGLSIYDFMKSN

G------FGPLSLREVRQVALRVLSALASLHNSGYIHCDIKPENIMLRRSTPVSS----DSSSFMLGPFTSENASSGSSNKSGEQNNFPNALAPGQAALK
.      . |. .. .|. |   ..|. .||  . .| | ||||| .     |.|    .. .| . .  . |                           
NSKMPNKYIPYPIDHIRHMAYQLCEAVKFLHDMKLTHTDLKPENICF-----VDSRFTHFDCTFKYNHKKKIN---------------------------

LDSNANAHNQLWRNTNSIDSLVGNTHSAAFQDSDLNMGFSPRTGNRLGGYSKQQHGQRGSGDATAAISGAGMRYSSSLDALFSMPAAAVGASGTGNSTRN
                                                                                                    
----------------------------------------------------------------------------------------------------

DLRVNCNALGNKGIESQERTQFNPDANPYRRT-----CLIDFGAVR--RFNENTYYD-VQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPG
                  ... |    .|..      |.||||  .  ||     .. |..  ||||||  ||.. .  | ||.||.|||| ||  .|..
------------------KKS-NNCVCHYWHVKNTHICVIDFGSATKIRFDHEHHSTIVSTRHYRAPEVILGLGWSQPCDVWSIGCILFELYTGFTLFQT





Kinase LmjF36.4250.AA DYRK 16-146 38 3.3e-45 156.52 In-house 1-138 (320) Show / Hide
Range on Protein: 16-146
Range on HMM: 1-138/320
Sequence Identity: 38% (53 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCLKEN--EDSVNI---LDSFEDAGHVCIVSELLDRNLFEVLRHRGFGPL-
|   ...| |..|||..|.|. |...||.|.  .  .. |.|..||. | .|...  .|. ..   .|.|   .|.||| |||. ||.|.|. ..| .. 
YEILEYIGKGSFGQVVKCWDHKTNEMVAIKIIRNNKRFHRQAQIEIKILEYLNQQDPDDKYHCVHMYDYFYHRNHLCIVFELLSMNLYEFLKNNHFQGFF

SLREVRQVALRVLSALASLHNS-GYIHCDIKPENIMLR
||. ||..|  .| .|  ||..  .||||.|||||||.
SLNLVRKFAQQILTCLKFLHKNENIIHCDLKPENIMLK

Kinase LmjF36.4250.AA Pkinase 16-398 16 9.1e-39 138.15 Pfam 1-229 (293) Show / Hide
Range on Protein: 16-398
Range on HMM: 1-229/293
Sequence Identity: 16% (69 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYR---RSALN--EISALLCLKENEDSVNI---LDSFEDAGHVCIVSELLDR-----NLFEVLR
|   ...| |..|.| .|..  ||| ||||.   . .     .....  ||. .. |.    . ||   .|.||| .|...| |...       ||....
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLN----HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIS

---HRGFGPLSLREVRQVALRVLSALASLHNSGYIHCDIKPENIMLRRSTPVSSDSSSFMLGPFTSENASSGSSNKSGEQNNFPNALAPGQAALKLDSNA
   |..|  .| .|.. ... .|..|. .|. | ||.|.|||||.. .   ...                                              
TWRHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDA----------------------------------------------

NAHNQLWRNTNSIDSLVGNTHSAAFQDSDLNMGFSPRTGNRLGGYSKQQHGQRGSGDATAAISGAGMRYSSSLDALFSMPAAAVGASGTGNSTRNDLRVN
                                                                                                    
----------------------------------------------------------------------------------------------------

CNALGNKGIESQERTQFNPDANPYRRTCLIDFGAVRR--FNENTYYDVQ--SLWYRAPEVLC-GLPYTTAIDSWSVGCVLFELFTGKPFFPGE----SLQ
                         . ...|||  .      |. ...   ..||.||||.  | .|....| ||.||.|.|...|.| |||.    .  
-------------------------CVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDN-H

HQLSLIVQ
 |. .|..
DQMQMICR

Kinase LmjF36.4250.AA HIPK 16-145 38 2.6e-37 114.71 In-house 1-134 (329) Show / Hide
Range on Protein: 16-145
Range on HMM: 1-134/329
Sequence Identity: 38% (52 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCLK-ENEDSVNI---LDSFEDAGHVCIVSELLDRNLFEVLRHRGFGPLSL
|    .|| ||.|||..|    |.  ||.|.   .. | |   .|.| | ||. || |  ..   .. |... |.|.| |.|. ||.. ..   | || |
YEVLEFLGRGTFGQVVKCWKRGTNEMVAIKILKNHPYYARQGQIEVSILHCLSQENADEYHFVRAYECFHHKNHTCLVFEMLEQNLYDFQKQNKFMPLPL

REVRQVALRVLSALASLHNSGYIHCDIKPENIML
. .| . . || ||. | . | || |.|||||||
KHIRPILQQVLTALMKLKELGLIHADLKPENIML

Kinase LmjF36.4250.AA DYRK2 16-152 35 4.3e-32 101.41 In-house 1-142 (318) Show / Hide
Range on Protein: 16-152
Range on HMM: 1-142/318
Sequence Identity: 35% (51 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCLKENEDS-----VNILDSFEDAGHVCIVSELLDRNLFEVLRHRGFGPLS
|   .|.| | .|||..|||  |.. ||.|.      . . |. ||  |  ....        | .||.|   .|.||. |||. || | .. . |  .|
YEILEVIGKGSFGQVVKCYDHKTKQHVAIKMIRNKKRFHNQAYEEIRILHHIRRQDKDNTMNCVHMLDYFYFRNHHCITFELLSMNLYEYIKKNHFQGFS

LREVRQVALRVLSALASLHNSGYIHCDIKPENIMLRRSTPVS
|..||  |  .| .|  ||    |||| |||||.|.  .. .
LQLVRRFAHSILQCLRFLHKNNIIHCDLKPENILLKQWNRSG

Kinase LmjF36.4250.AA DYRK 328-405 50 4.4e-32 112.9 In-house 148-225 (320) Show / Hide
Range on Protein: 328-405
Range on HMM: 148-225/320
Sequence Identity: 50% (39 aa)

LIDFGAVRRFNENTYYDVQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPGESLQHQLSLIVQHVGHPSQ
.||||     ..  |  .||  ||||||..|.|| .||| ||.||.| |||||.|.||||. ..|| .|..  | |..
VIDFGSSCFEHQRIYTYIQSRFYRAPEVILGCPYCYAIDMWSLGCILAELFTGWPLFPGENEYDQLACIMEVLGMPPK

Kinase LmjF36.4250.AA DYRK2 328-405 43 1.6e-29 92.88 In-house 145-223 (318) Show / Hide
Range on Protein: 328-405
Range on HMM: 145-223/318
Sequence Identity: 43% (34 aa)

LIDFGAVRRFNE-NTYYDVQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPGESLQHQLSLIVQHVGHPSQ
.||||  .  ..   | ..||. |||||| .|..| .||| || ||.. ||.||.|.||||  . |. ..    | |..
VIDFGSSCFEHQYRIYTYIQSRFYRAPEVILGGKYGMAIDMWSFGCIMAELYTGYPLFPGENENDQFACMMEVLGMPPK

Kinase LmjF36.4250.AA YAK 16-146 37 2.6e-27 89.55 In-house 1-140 (347) Show / Hide
Range on Protein: 16-146
Range on HMM: 1-140/347
Sequence Identity: 37% (53 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCL-----KENED----SVNILDSFEDAGHVCIVSELLDRNLFEVLRHRGF
||   .|| ||.|||. |  . |   .||||  .  ||   | |||  |  |      .|.      ....|.|    | |.| |.|  ||.| |    |
YIVLDMLGQGTFGQVVKCQNCDTNELFAVKVIKNRQAYFQQAKNEIQILRVLNQQHDPNNKNYQKHILRMYDFFVHKNHFCLVFEMLSNNLYEYLKQNKF

GPLSLREVRQVALRVLSALASLHNSGYIHCDIKPENIMLR
  .|   .||    .| ..  | |.  |||| |||||||.
CGFSFQLIRQWTKQILDGMCVLENKQIIHCDLKPENIMLC

Kinase LmjF36.4250.AA CAMK 21-145 16 5.3e-26 80.18 In-house 1-212 (425) Show / Hide
Range on Protein: 21-145
Range on HMM: 1-212/425
Sequence Identity: 16% (36 aa)

VLGTGTYGQVIRCYDNVTG------------KDVAVKV-----AQSD------------------------AAYRRSALNEISALLCLKE------NEDS
.||.|..|.| .|..  |.            . ||.|.     ....                        .  |.. ..||. .  |..       .  
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VNILDSFEDAGH-------------------VCIVS---ELLDRN-----LFEVLRHRGF-------------GPLSLREVRQVALRVLSALASLHNSGY
..... .||. .                   ...|    |. .       ||. .. .|              | .. ||.|..   ..||.. .|. . 
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIVERGRFTEREARRYFRQICSAVHYCHSHNI

IHCDIKPENIML
.|.|.|||||.|
VHRDLKPENILL

Kinase LmjF36.4250.AA MAPK 345-405 44 5.9e-23 76.04 In-house 192-256 (328) Show / Hide
Range on Protein: 345-405
Range on HMM: 192-256/328
Sequence Identity: 44% (29 aa)

VQSLWYRAPEVLCG---LPYTTAIDSWSVGCVLFELFT-GKPFFPGESLQHQLSLIVQHVGHPSQ
|   ||||||....     ||.|.| ||||| . |. | .||.|||.. ..|. ||.. .| ||.
VATRWYRAPEIMLNWIWMHYTKAVDMWSVGCIFAEMLTDRKPLFPGKDYIDQWNLIMEVLGTPSE

Kinase LmjF36.4250.AA YAK 328-403 40 3.6e-21 68.33 In-house 149-224 (347) Show / Hide
Range on Protein: 328-403
Range on HMM: 149-224/347
Sequence Identity: 40% (31 aa)

LIDFGAVRRFNENTYYDVQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPGESLQHQLSLIVQHVGHP
.||||         |  .|. .||.||.. . .|.|.|| || ||.. ||| | | ||| |   |.. |.   | |
IIDFGSSCQEKKMVYTYIQQRHYRSPEIIVWMIYCTSIDMWSLGCIVAELFLGLPIFPGNSEYNQIKRIIDMLGYP

Kinase LmjF36.4250.AA DYRK1 328-417 38 4.7e-21 70.29 In-house 147-236 (321) Show / Hide
Range on Protein: 328-417
Range on HMM: 147-236/321
Sequence Identity: 38% (35 aa)

LIDFGAVRRFNENTYYDVQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPGESLQHQLSLIVQHVGHPSQAALTLGCLATQF
.||||.  . ..  |  .|| .||.|||| |..| .||| ||.||.| |. || | | | . . |.. ||  .| | .. .  .  | ..
IIDFGSSCQLGQRIYQYIQSRFYRSPEVLLGIEYDMAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNKIVEVLGMPPKHMIDQAPKAHKY

Kinase LmjF36.4250.AA DYRK1 16-146 33 6.7e-20 66.17 In-house 1-138 (321) Show / Hide
Range on Protein: 16-146
Range on HMM: 1-138/321
Sequence Identity: 33% (47 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCLKENEDS------VNILDSFEDAGHVCIVSELLDRNLFEVLRHRGFGPL
|  .  .| | .|||.. ||... . ||.|. .   ..   |. ||  || |  ..|       |..   |    |.|.| |||  ||...||   |   
YEIDSLIGKGSFGQVVKAYDHQEQEYVAIKIIKNKKPFYNQAQIEI-RLLELMNKHDKEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGV

SLREVRQVALRVLSALASLHNSGY--IHCDIKPENIMLR
||  .|. |  .. ||  .       ||||.|||||.|.
SLNLTRKFAQQMCTALLFMSTPELDIIHCDLKPENILLC

Kinase LmjF36.4250.AA PRP4 328-388 50 8.1e-17 58.14 In-house 148-209 (320) Show / Hide
Range on Protein: 328-388
Range on HMM: 148-209/320
Sequence Identity: 50% (32 aa)

LIDFGAVRRFNEN--TYYDVQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPGES
..|||   . .||  | |  .|  |||||.. | ||  .|| ||||| |.||.|||  ||| .
MCDFGSASHIHENEITPY-LVSRFYRAPEIIIGHPYDYQIDMWSVGCTLYELYTGKIMFPGKT

Kinase LmjF36.4250.AA HIPK 318-417 39 1.5e-16 48.21 In-house 137-236 (329) Show / Hide
Range on Protein: 318-417
Range on HMM: 137-236/329
Sequence Identity: 39% (41 aa)

PDANPYRRTCLIDFGAVRRFNE---NTYYDVQSLWYRAPEVLCGLPYTTAIDSWSVGCVLFELFTGKPFFPGESLQHQLSLIVQHVGHPSQAALTLGCLA
|   || |   ||||    . .   |||  .|| .|||||.. |||.  ..|.|| |||. ||| | | .|| .   |   | |  . | .  |  .| .
PTRCPY-RVKVIDFGSASHVSKVVCNTY--LQSRYYRAPEIILGLPFCENHDMWSLGCVIAELFLGWPLYPGADEYDQIRYICQTQHLPHEHLLHAACKK

TQF
..|
HRF

Kinase LmjF36.4250.AA PRP4 16-144 30 4.4e-13 44.3 In-house 1-138 (320) Show / Hide
Range on Protein: 16-144
Range on HMM: 1-138/320
Sequence Identity: 30% (42 aa)

YIPNKVLGTGTYGQVIRCYDNVTGK-DVAVKVAQSDAAYRRSALNEISALLCLKEN----EDSVNIL---DSFEDAGHVCIVSELLDRNLFEVLRHRGFG
|  .   | | .. |.|| |.  |. .||.|.  .    ... | |.  |  | ..    .|   ..   ..|.   | |.| | .  || |||   | .
YRVYGYCGQGVFSNVCRCRDQTRGNEMVAIKIIRNNEIMHKTGLRELEILQKLNDAPTDKNDKFHCVRMFRHFNHRQHMCLVFECMSMNLREVLKKYGKD

P-LSLREVRQVALRVLSALASLHNSGYIHCDIKPENIM
  |.|  ||  |   . ||  | .....| |||| ||.
VGLHLKAVRSYAQQLFLALKHLKKCNILHADIKPDNIL

Kinase LmjF36.4250.AA CAMK 508-533 34 7.7e-09 23.87 In-house 400-425 (425) Show / Hide
Range on Protein: 508-533
Range on HMM: 400-425/425
Sequence Identity: 34% (9 aa)

DLVCDLLNPDESQRLSCTQALRHPFL
||.. .|..| ..|....|.|.||..
DLIRKMLQVDPEKRMTIEQCLNHPWM

Kinase LmjF36.4250.AA CAMK 352-382 31 5.2e-08 21.15 In-house 288-332 (425) Show / Hide
Range on Protein: 352-382
Range on HMM: 288-332/425
Sequence Identity: 31% (14 aa)

APEVLCG--------------LPYTTAIDSWSVGCVLFELFTGKP
||||| |               .|. ..| ||.|..|. . .|.|
APEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYP

Kinase LmjF36.4250.AA Pkinase 508-533 30 1.6e-07 27.65 Pfam 268-293 (293) Show / Hide
Range on Protein: 508-533
Range on HMM: 268-293/293
Sequence Identity: 30% (8 aa)

DLVCDLLNPDESQRLSCTQALRHPFL
|.....|..| ..|....|.| ||..
DFIKWCLCKDPKKRPTAEQILQHPWF

Kinase LmjF36.4250.AA CMGC 504-533 33 4.2e-07 18.4 In-house 484-513 (513) Show / Hide
Range on Protein: 504-533
Range on HMM: 484-513/513
Sequence Identity: 33% (10 aa)

ELLVDLVCDLLNPDESQRLSCTQALRHPFL
....||.. .|  | ..|... |||.||..
PQAIDLLKKMLQYDPDKRITAEQALQHPYF

Kinase LmjF36.4250.AA MAPK 16-45 36 6.2e-07 19.78 In-house 1-36 (328) Show / Hide
Range on Protein: 16-45
Range on HMM: 1-36/328
Sequence Identity: 36% (13 aa)

YIPNKVLGTGTYGQVIRCYDNV------TGKDVAVK
| . | .| | ||.|  ..|.       .|| ||.|
YQILKPIGQGAYGVVCSAIDKRTNQKTKCGKKVAIK

Kinase LmjF36.4250.AA DYRK 502-533 28 1e-06 20.8 In-house 289-320 (320) Show / Hide
Range on Protein: 502-533
Range on HMM: 289-320/320
Sequence Identity: 28% (9 aa)

ELELLVDLVCDLLNPDESQRLSCTQALRHPFL
. ....|..  .|. | ..|... |||.||..
DDHQFKDFIKKCLQWDPHKRITPSQALQHPWF

Kinase LmjF36.4250.AA CLK 500-533 41 2e-06 14.4 In-house 317-350 (350) Show / Hide
Range on Protein: 500-533
Range on HMM: 317-350/350
Sequence Identity: 41% (14 aa)

SEELELLVDLVCDLLNPDESQRLSCTQALRHPFL
..| . | ||.  .|  | |.|..| .|| ||| 
DPEHRQLFDLIRKMLEYDPSKRITCKDALQHPFF

Kinase LmjF36.4250.AA MAPK 507-533 33 3e-06 17.22 In-house 302-328 (328) Show / Hide
Range on Protein: 507-533
Range on HMM: 302-328/328
Sequence Identity: 33% (9 aa)

VDLVCDLLNPDESQRLSCTQALRHPFL
.||.. .|  | ..|..  .||.||..
IDLLEKMLVFDPDKRITVEEALQHPYF

Kinase LmjF36.4250.AA TyrKc 16-428 11 8e-06 -128.41 SMART 1-280 (280) Show / Hide
Range on Protein: 16-428
Range on HMM: 1-280/280
Sequence Identity: 11% (53 aa)

YIPNKVLGTGTYGQVIRCYDNVTGKDVAVKVAQSDAAYRRSALNEISALLCL-KENEDSVNILDSFEDA-------GHVCIVSELLDR-NLFEVL-RHRG
   .|.|| | .|.| ..  .    .||||. ..||  |.  ..|.. .  | ....  |...    .        . ..|| |. .  .| . | .||.
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

FGPLSLREVRQVALRVLSALASLHNSGYIHCDIKPENIMLRRSTPVSSDSSSFMLGPFTSENASSGSSNKSGEQNNFPNALAPGQAALKLDSNANAHNQL
   |....  . .. . .  . ||  ..|| |.   |... .                                                          
K--LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH--------------------------------------------------------

WRNTNSIDSLVGNTHSAAFQDSDLNMGFSPRTGNRLGGYSKQQHGQRGSGDATAAISGAGMRYSSSLDALFSMPAAAVGASGTGNSTRNDLRVNCNALGN
                                                                                                    
----------------------------------------------------------------------------------------------------

KGIESQERTQFNPDANPYRRTCLIDFGAVRRFNEN-------TYYDVQ---SLW------YRAPEVLCGLPYTTAIDSWSVGCVLFELFT-GKPFFPG--
                   .    |||  |   .         ||...   .          |||..    .||. | || | ...|.|| |..  ||  
-------------------TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMI

----------ESLQHQLSLIVQHV--------GHPSQAALTLGCLATQFQ--LPMVYVSHDA
          | ...   .   .          ..    . . | . .      .  . .. 
QQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF

Kinase LmjF36.4250.AA YAK 504-533 30 1.2e-05 14.79 In-house 318-347 (347) Show / Hide
Range on Protein: 504-533
Range on HMM: 318-347/347
Sequence Identity: 30% (9 aa)

ELLVDLVCDLLNPDESQRLSCTQALRHPFL
....|..  ||. .   | .  ||  |||.
DCFIDFINQLLQLNPRERWKPMQAMQHPFI

Kinase LmjF36.4250.AA MAPK 86-143 30 2.4e-05 14.21 In-house 91-148 (328) Show / Hide
Range on Protein: 86-143
Range on HMM: 91-148/328
Sequence Identity: 30% (18 aa)

VCIVSELLDRNLFEVLRHRGFGPLSLREVRQVALRVLSA--LASLHNSGYIHCDIKPENI
..||.|| . .|  ... .   |||   ..     .| .  |  .|  . ||.|.||.||
IYIVMELMETDLHQIIKSQQ--PLSDDHIQYFMYQILRGLKLKYIHSANVIHRDLKPSNI

Kinase LmjF36.4250.AA DYRK2 517-533 47 7.6e-05 11.33 In-house 302-318 (318) Show / Hide
Range on Protein: 517-533
Range on HMM: 302-318/318
Sequence Identity: 47% (8 aa)

DESQRLSCTQALRHPFL
| |.|..  |||.||..
DPSERMTPSQALKHPWI

Kinase LmjF36.4250.AA PRP4 517-533 47 0.000158 12.59 In-house 304-320 (320) Show / Hide
Range on Protein: 517-533
Range on HMM: 304-320/320
Sequence Identity: 47% (8 aa)

DESQRLSCTQALRHPFL
| . | .| .||.|||.
DPKKRITCNEALKHPFI

Kinase LmjF36.4250.AA DYRK1 508-533 38 0.002515 6.97 In-house 296-321 (321) Show / Hide
Range on Protein: 508-533
Range on HMM: 296-321/321
Sequence Identity: 38% (10 aa)

DLVCDLLNPDESQRLSCTQALRHPFL
||.  .|. |  ||..  .||.|.|.
DLIKRMLQYDPKQRITPYYALQHSFF

Kinase LmjF36.4250.AA HIPK 507-533 29 0.009163 3.98 In-house 303-329 (329) Show / Hide
Range on Protein: 507-533
Range on HMM: 303-329/329
Sequence Identity: 29% (8 aa)

VDLVCDLLNPDESQRLSCTQALRHPFL
|..   ..  |  .|..  .||.||| 
VHVLKKMCTWDAHKRITPCEALNHPFV