Gene LmjF22.0810 (L.major)

LmjF22.0810

Species: L.major
Alias: LmjF22.0810, LmajK033
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CIPK

Sequence

Name Sequence Type Origin Length Description Download
LmjF22.0810.AA Protein None 372 None Fasta, JSON
LmjF22.0810.kin_dom Protein Kinase Domain None 259 None Fasta, JSON

Protein domain

Protein domains of LmjF22.0810.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
S_TKc LmjF22.0810.AA S_TKc 8-266 32 1e-91 311.89 SMART 1-231 (231) Show / Hide 
Range on Protein: 8-266
Range on HMM: 1-231/231
Sequence Identity: 32% (90 aa)

YEILDVVGEGAYSKVKRVRHIPTGCMFVAKIVPKTNQQVENDVRLEISILRRLKHKNIVQLIEILESTNNYYIILEPVMG--GDLCDIIVGMDRP-----
||||...|.||..||...||. ||  .  ||..       ...| ||.||.. .|.|||.|... .. ...|...| . |  ||| |.|. . |.     
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LPEQDVAALLIQLVAGVRACHRNGVAHRDLKPENLLLGTDGVLKISDFGLSRLHRESNFQASTNEYAHTLTGTLAYLAPEVFGGSYDAFRADIWSMGCIA
.|| ... .. |.. ..  ||..|. ||||||||.|| .  ..||.||||.|.              .|. ||. |.||||.  .|. ...|.|| ||| 
FPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCIL

YVLLTQNFPFGSTTDPHALEVRIRNGEVSVMPSSVSAEAKNLCKWLLSPRPEDRPTLDAVAQ-------HDFF
| .|.   ||    .....  .|.           | |||.. . .|   ||.|||   . |       | .|
YEMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF22.0810.AA CAMK 13-266 19 1.2e-90 292.26 In-house 1-425 (425) Show / Hide 
Range on Protein: 13-266
Range on HMM: 1-425/425
Sequence Identity: 19% (84 aa)

VVGEGAYSKVKRVRHIPTG------------CMFVAKIVPKT----------------------------NQQVENDVRLEISILRR-------LKHKNI
. |.|...|||...|. |.              . .||..|.                            ... .  || ||.|...       |.|.||
TLGRGSFGKVKLCIHKNTTGKERVHHIYTNGQKVAIKIIDKKKLKDKQNQDYSNCYKIDKSKCKHRYCWRRPKDRKNVRREIEIMKKLQGIGNKLDHPNI

VQLIEILES-------------------TNNYYIIL---EPVMGGDLCDI-------------------IVGMDRPLPEQDVAALLIQLVAGVRACHRNG
..|.|. |.                   ....|...   | . ||.|.|                    || ... ..|.... .  |.. .|. || ..
IKLYEVYEDPHYFKNTNDYETSKQVFTKDKHMYMVMEIMEYCSGGELFDDLFDYIVEHGCYGEEFDQFDIV-ERGRFTEREARRYFRQICSAVHYCHSHN

VAHRDLKPENLLLGTD-----------------GVLKISDFGLSRLHRESNFQA-----------------STNEYAHTLTGTLAYLA-PEVFGG-----
..||||||||.|| ..                 . .||.|||...  .... .                   ...  .|  ||..| | |||. |     
IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQWTTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCN

---------SYDAFRADIWSMGCIAYVLLTQNFPFGSTT------------DPHALEVRIRNGEVSVMPSS-----------------------VSAEAK
          |. . .|.||.|.| |..|.  .|| . .            ... |  .|..|. .  |.                        ||.|.|
MQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKGKYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECK

NLCKWLLSPRPEDRPTLDAVAQHDFF
.| ...| . ||.|.|.. . .| ..
DLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF22.0810.AA CAMKL 8-266 30 1.2e-86 276.5 In-house 1-297 (297) Show / Hide 
Range on Protein: 8-266
Range on HMM: 1-297/297
Sequence Identity: 30% (91 aa)

YEILDVVGEGAYSKVKRVRH-IPTGCMFVAKIVPKT----NQQVEND-----------VRLEISILRRLK---HKNIVQLIEILESTNN------YYIIL
|.|... |.|...|||  .| . ||..   ||. |     ......            .| ||.|...|.   |.||..| |..|  ..      .|...
YRIGKTLGKGSFGKVKLATHIRTTGEKVAIKIIDKKKIWNDPWMKKNKCGQKHESDMRIRREIQIMKMLNIGKHPNIIKLYEVIETPEHDIETKKIYLVM

EPVMGGD--LCDII--VGMDR-PLPEQDVAALLIQLVAGVRACHRNGVAHRDLKPENLLLGTDG--VLKISDFGLSRLHRESNFQ-ASTNEYAHTLTGTL
| . ||.  | | |   |  | ..|| .   .  |.|..|  ||..|..|||.||||.||  .|  ..||.|||.| ..|.   .   ...  .|  |..
EYCSGGEMDLFDYIVKHGHRRGRMPEHEARRYFRQIVSAVNYCHSHGIVHRDIKPENILLDENGNNNIKIIDFGFSNMYRP---CIFGPGQKLKTFCGSP

AYLAPEVFGG---SYDAFRADIWSMGCIAYVLLTQNFPFGSTT-------DPHALEVRIRNGEVSV-MPSSVSAEAKNLCKWLLSPRPEDRPTLDAVAQH
.| |||.| |   .||.. .||||.| | |.... ..||   |       .   |. .|. |      ...|| ....| ...| . ||.|||.. . .|
PYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG-YYPPIWYHVS-DCRDLIRKMLQVNPEKRPTIHQIMNH

DFF
 ..
PWM
Pkinase LmjF22.0810.AA Pkinase 8-266 29 4e-85 293.91 Pfam 1-293 (293) Show / Hide 
Range on Protein: 8-266
Range on HMM: 1-293/293
Sequence Identity: 29% (89 aa)

YEILDVVGEGAYSKVKRVRHIPTGCMFVAKIVPKTNQQVENDVRL----EISILRRLKHKNIVQLIEILESTNNYYIILEPVMGG----DLCDIIV-GMD
|.|. ..|.|....|.. .|. ||.... ||..| ..  . |...    ||.|..||.|.|||.|... |. ...|...| ..||    ||.|.|   ..
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RPL--PEQDVAALLIQLVAGVRACHRNGVAHRDLKPENLLLGTDGVL----KISDFGLSRLHRESNFQASTNEYAHTLTGTLAYLAPEVFG-GSYDAFRA
...  .|...   . |.. |.  ||..|. ||||||||.|.  .|..    ||.||||.....        |. ..|..||. |.||||   |.|.  ..
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-----Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DIWSMGCIAYVLLTQNFPFGST-----TDPHALEVRIRNGEVSVMPSSVS--------------------AEAKNLCKWLLSPRPEDRPTLDAVAQHDFF
|.||.||| | .|. ..|| .       |. .. .||. ....   .  .                     |.| ..||.| . |..||| . . ||..|
DMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF22.0810.AA AGC 8-266 21 1.3e-79 204.72 In-house 1-395 (395) Show / Hide 
Range on Protein: 8-266
Range on HMM: 1-395/395
Sequence Identity: 21% (84 aa)

YEILDVVGEGAYSKVKRVRHI------PTGCMFVAKIVPKTN----------QQVEND--------VRLEISILRRLK----------HKNIVQ-LIEIL
.|.| |.|.|...||  ||.        || ..  |.. |            ... .         |. |  || ...          | .||. |    
FEFLKVIGKGSFGKVYLVRKKDGCHKKDTGKYYAMKVLKKKHKIVIKKKNMVEHTMTEHWKQDQGYVWEERNILEKCNHTHNHPIKSHHPFIVKILHYSF

ESTNN--YYIILEPVM---------GG-DLCDIIVGM-DRP-LPEQDVAALLIQ-------LVAGVRACHR-NGVAHRD-LKPENLLLGTDGVLKISDFG
.. ..   |...| .          || .|  .. |. ..  ..|. .   . .       .| ..   |. .|. ||| |||||.||  || .|..|||
QDKDHTYLYFVMEYMPRYVNDLYCGGGCELFLHLQGRRKEGRFDEERARFYAAEMQKICGCIVLALEYLHSHMGIIHRDYLKPENILLDEDGHIKLTDFG

LSRLHRESN---------------------------------FQAST-----------NEYAHTLTG--TLAYLAPEVFGGSYDAFRADIWS--MGCIAY
|.   . ..                                 .|.             .. ..|. |  |  |.|||..      . .|.||  .||. |
LCKEGMNDGEKGQQSQSNMKFHWHNKKYQKSNMDTNKCNPNNWQRNNMSQEDDTTRKKRDRTWTFCGPCTPEYMAPEIL----YGKACDWWSFGLGCLMY

VLLTQNFPFGSTT---------DPHALEVRIRNG-----EVSVMP----------SSVSAEAKNLCKWLLSPRPEDRPT----------LDAVAQHDFF
 .||   || . .         .|. .  .|.||     .   .|          ...| |||.|.| || . ||.|..           . . .| .|
EMLTGYPPFYGDNPQENRHPFRNPMEMFQKIMNGRYFINWKVKFPFPEDPQFPEDRWFSPEAKDLIKKLLCKDPEKRLGCGGNDFGDKGAEEIKNHPWF
Kinase LmjF22.0810.AA MARK 8-266 34 4.7e-69 224.91 In-house 1-262 (262) Show / Hide 
Range on Protein: 8-266
Range on HMM: 1-262/262
Sequence Identity: 34% (93 aa)

YEILDVVGEGAYSKVKRVRHIPTGCMFVAKIVPKTNQQV---ENDVRLEISILRRLKHKNIVQLIEILE--STNN-YYIILEPVMGGDLCDIIVGM-DRP
|..| . |.|.|.||| ..|..||  .  ||..|.. .     . |. ||.|...|.|.||..| .. |   ...  |.|.| . ||.| | |.   ...
YKMLKTIGHGSYAKVKLACHKHTGRKVAIKIYEKFKLNDPQWMKNVMREIEIMKKLDHPNIIKLFHVIEQDTEQHQIYLIMEYASGGELYDYIKAHPNGR

LPEQDVAALLIQLVAGVRACHRNGVAHRDLKPENLLLGTDG--VLKISDFGLSRLHRESNFQASTNEYAHTLTGTLAYLAPEVFGG-SYDAFRADIWSMG
|.| .  ..  |.| .|  ||.....|||.||||.|.  .|    ||.|||.|.       .  ...   |  ||..| |||.| .  ||.. .||||.|
LHEEEARRIFRQIVSAVNYCHSKNIVHRDIKPENILIDENGNHNIKIIDFGFSI-------CIPPGQKLNTFCGTPPYMAPEIFLKKPYDGPKVDIWSLG

CIAYVLLTQNFPF-GSTTDPHALEVRIRNGEVSVMPSSVSAEAKNLCKWLLSPRPEDRPTLDAVAQHDFF
 . |.... .||| |.| |   |. .|..|. .  |. ||.|..|| ..|| . ||.|||.. . .| ..
VVLYFMVCGYFPFDGDTQDYKELYKKILRGKYD-IPCHVSKECRNLIQRLLTVNPEERPTIEEIMKHPWM
Kinase LmjF22.0810.AA Ciliate-E2 8-266 20 3.4e-63 215.76 In-house 1-365 (365) Show / Hide 
Range on Protein: 8-266
Range on HMM: 1-365/365
Sequence Identity: 20% (78 aa)

YEILDVVGEGAYSKVKRVRHIPTGCMF-----------------VAKIVPKTNQQVEND---VRLEISILR----------------RLKHKNIVQLIEI
|... . |.|....|...... ....|                 |..     ... .|.   .  ||.|.|                .|.|.||....| 
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

LE--STNNYYIILEPVMGGDLCDIIVGMDR----------PLPEQDVAALLIQLVA---------------GVRACHRNG-VAHRDLKPENLLLGTDGVL
 .  ..||.|...| . |||| |.|  ..           .. |. .. .  |..                ... .| .. . |||.||||.|.     .
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----I

KISDFGLSR---------LHRESNFQASTNEY------------------AHTLTGTLAYLAPEVFGG-SYDA--------FRADIWSMGCIAYVLLTQN
||.|||||.         .|  .  .  ..                    ..|. ||. |.|||...| .||         . .||||.|.| | .|. .
KIIDFGLSKKYDDDNQNRTH-KQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFGK

FPFGSTTDPHALEVRIRNGEVSVM-----------------PSSVSAEAKNLCKW----LLSPRPEDRPT-LDAVAQHDFF
.||         .  | .....                   . ..| |.|.|.|     .|   || |.|  . . .| .|
PPF---------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPEKRITGWEQILNHPWF
Kinase LmjF22.0810.AA AMPK 8-266 37 1.9e-62 184.25 In-house 1-254 (254) Show / Hide 
Range on Protein: 8-266
Range on HMM: 1-254/254
Sequence Identity: 37% (99 aa)

YEILDVVGEGAYSKVKRVRHIPTGCMFVAKIVPK---TNQQVENDVRLEISILRRLKHKNIVQLIEIL-ESTNNYYIILEPVMGGDLCDIIVGMDRPLPE
| | .  |||.. |||   || ||     ||  |   ..|.. . .. ||.||. ..| .|.|| |.. |..   ....| | ||.| | ||  .| |.|
YIIGKTIGEGTFGKVKMGTHILTGEKVAIKILNKQKIKDQDMVERIQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKHGR-LQE

QDVAALLIQLVAGVRACHRNGVAHRDLKPENLLLGTDGVLKISDFGLSRLHRESNFQASTNEYAHTLTGTLAYLAPEVFGG-SYDAFRADIWSMGCIAYV
.. . .. | ..||  |||....|||||||||||  .  .|| ||||| .  .       .|.  |  |   | |||.  |  |     |||| | | |.
REACRFFQQIISGVEYCHRHMIVHRDLKPENLLLDHNKNIKIVDFGLSNMMKD-------GEFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYA

LLTQNFPFGSTTDPHALEVRIRNGEVSVMPSSVSAEAKNLCKWLLSPRPEDRPTLDAVAQHDFF
.|    ||     | .|  .|.|||... |. .| |||.| | .| . |. | | ... .|..|
MLCGYLPFDDENTP-TLYKKIKNGEYYI-PKFLSPEAKDLIKHMLQVDPMKRITIHDIRNHPWF
Kinase LmjF22.0810.AA Ciliate-E2-Unclassified 8-266 23 3.9e-62 212.75 In-house 1-352 (352) Show / Hide 
Range on Protein: 8-266
Range on HMM: 1-352/352
Sequence Identity: 23% (83 aa)

YEILDVVGEGAYSKVKRVRHIPTGCMF-----VAKIVPKTNQQVEN--------DVRLEIS-------------ILRRLKHKNIVQLIEILESTNNYYII
|.|. . |.|...||....|. ..  .       ||  .  .|..|        .   ...             ||. ..| .|| .... ....| ||.
YKIIKQIGQGGFGKVYKCQHKKQK-QYYAMKYMKKIQIYKQKQIMNKDEIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

LEPVMGGDLCDIIV--------GMD--------RPLPEQDVA-----ALLIQLVAGVRACHRNG-VAHRDLKPENLLLGTDG---VLKISDFGLSRLHRE
.| . |||| ..|         | |        . ..|| ..      .. |.. |   .|... . |||.||||.|.  .|    .||.|||.|.   .
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQ

SNFQASTN----------EYAHTLTGTLAYL----APEVFGG-SYDA---FRADIWSMGCIAYVLLTQNFPFGSTTDPH---------------ALEVRI
.| .  ||          . ..| .||. |.    ||||..|  ||    . .||||.|.|.| .|....||.....                  |.  |
NNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNI

RNGEVSVMP-------SSVSAEAKNLCK----WLLSPRPEDRPTLDAVAQHDFF
 ...... .         .| |||....     .|  .|. |.|.. . .| .|
KQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKRITFEQILNHPWF
Kinase LmjF22.0810.AA Ciliate-E2a 8-210 32 1.3e-55 162.18 In-house 1-216 (275) Show / Hide 
Range on Protein: 8-210
Range on HMM: 1-216/275
Sequence Identity: 32% (73 aa)

YEILDVVGEGAYSKVKRVRHIPTGCMFVAKIVPKTNQQVE---NDVRLEISILRRLKHKNIVQLIEILESTNNYYIILEPVMGGDLCDIIVGMDRPLPE-
|..... |.|.. .|. ..|. || .|..|.. | ..| .     .  ||.|.|.|.|.|| .|.|. |. ||||...| . ||.| | |.  .|   | 
YKFIKKIGKGNFGSVYLAQHKQTGKQFAMKKFIKKMYQQKKGKEYFMNEINIMRQLDHPNIIKLYEVYEDENNYYLVMEYCEGGELYDKIKQCKRFFEEI

QDVAALLIQLV-AGVRACHRNGVAHRDLKPENLLLG---TDG----VLKISDFGLSRLHRESNFQASTNEYAHTLTGTLAYLA------PEV-FGGSYDA
|... .. ||   |.  .| ... ||||||||.|.    ...     .||.||||..     ...   ..| ..  ||  |.|      .|| .. .|| 
QEICDIMQQLLWQGLHYMHQRNIMHRDLKPENILFKNCSKNSIQNSDIKIIDFGLAT-----FIDKDEKKYMFQKCGTPGYVAPEVLNNKEVLKHKQYD-

FRADIWSMGCIAYVLLTQNFPF
   |.|| |.| | ||.   ||
TKCDMWSCGVIFYILLCGKPPF
Kinase LmjF22.0810.AA ULK 8-266 26 3.9e-54 186.18 In-house 1-329 (329) Show / Hide 
Range on Protein: 8-266
Range on HMM: 1-329/329
Sequence Identity: 26% (87 aa)

YEILDVVGEGAYSKVKRVRHIPT----GCMFVAKIVP---KTNQQVEND-------VRLEISILRRLK----HKN----IVQLIEILEST--NNYYIILE
|.. .. |.|.. || . |.. |    . ....|...   . ... |..       .. || |...||    |||    ||.|....|..  ||.|||.|
YCLNHCLGKGSFGKVYKGRNKKTKDYVNEKVACKMIDKQKMNQKNNEQEGQYMWQLLKNEIKIMKKLKSPNRHKNHHPNIVKLYDWFETSNHNNIYIIME

PVMGGDLCDIIV-----GMDR----PLPEQDVAALLIQLVAGVRACHRNGVAHRDLKPENLLLGTD------------GVLKISDFGLSRLHRESN----
   |||| ..|      ..|      |.|| .   ..|...| .. | ... |||.||.| |.  .            |||||.|||...   ..|    
YCNGGDLEQYIKKNKKLPEDTEEKKRLSEQEAIQFFKQILNGFKELHKHNIIHRDIKPQNILIHNGQPKTDSKKVHPNGVLKIADFGFAKHVDNDNMEQQ

-FQASTNEYAHTLT---GTLAYLAPEVFGGS-----YDAFRADIWSMGCIAYVLLTQNFPFGST-TDPH-----ALEVR-------IRNGEVSVMP----
 ... .||     .   ||  | ||... |      |. . .||||.||| | .|.   || .  .|        |          |..      .    
MMMTCVNE-----KRLCGTPLYMAPQILQGQGEQKPYYDYKCDIWSLGCIFYEMLYGKPPFYAWFNDQYLQIIQKLINNPPPWPQQIKKQPLQFPKDGND

SSVSAEAKNLCKWLLSPRPEDRPTLDAVAQHDFF
  .| | |.| . .|   ..|| . . . .| .|
PQISPECKDLIRRMLQYDEKDRISWEELFNHPWF
Kinase LmjF22.0810.AA RSK 10-266 25 2.6e-53 183.44 In-house 1-278 (278) Show / Hide 
Range on Protein: 10-266
Range on HMM: 1-278/278
Sequence Identity: 25% (71 aa)

ILDV--VGEGAYSKVKRVRHIPTGCMFVAKIVPKTNQQVEN----DVRLEISILRRLK-HKNIVQLIEILESTNNYYIILEPVMGGDLCDIIVGMDRP--
. .    | |... .....|  ||  .  |.. |    . .    ... |..|| | . |..||.| .  .     |.|.| ..||.| . .    .   
LKVLGQGGYGKVFLCRKCTHHDTGQIYAMKVLKKAKIVQRQKDTRHTMTERNILERCQQHPFIVTLHYAFQTEGKLYLIMEYCRGGELFTHLQKEKHFGC

LPEQDVAALLIQLVAGVRACHRNGVAHRDLKPENLLLGT---DGVLKISDFGLSRLHRESNFQASTNEYAHTLTGTLAYLAPEVFG----GS-YDAFRAD
. | .... . ..|  |.  |  |. |||||||| |.     .| .|..|||....       .. |. ..|  .|..|.|||.      .. .|.  .|
FSEDEACFYMAEIVLAVEHLHQQGIIHRDLKPENILYDDESNEGHIKLTDFGFCKQF-----RCDHNQWTMTFCYTIEYMAPEMLKRANQQGGHDK-ACD

IWSMGCIAYVLLTQNFPFGS--TTDPHALEVRIRNGE--VSVM-PSSVSAEAKNLCKWLLSPRPEDRPT-----LDAVAQHDFF
.|| |.. | .|| . || .    ... .  ||..|.  .. . ....|.|||.| ...|   |..|..     .. . || .|
WWSLGVLMYEMLTGCPPFQGPNDNNRKEIMKRIQKGKFSLTMPNWQYLSQEAKDLIRKMLHRDPHKRLGCGPQDAEEIKQHPWF
Kinase LmjF22.0810.AA TyrKc 8-266 23 1.6e-15 28.49 SMART 1-280 (280) Show / Hide 
Range on Protein: 8-266
Range on HMM: 1-280/280
Sequence Identity: 23% (68 aa)

YEILDVVGEGAYSKVKRVRHIPTGCMFVA-KIVPKTNQQVENDVRLEISILRRL--KHKNIVQLIEILEST-------NNYYIILEPVMGGDLCDIIVGM
 . ... ||||. .| . . .    . || | . .     . | . |..|...|  .|.|||.|. .  .          ..|..| . .||| | .   
ITLGKKLGEGAFGEVYKGTWK----IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

DRPLPEQDVAALLIQLVAGVRACHRNGVAHRDLKPENLLLGTDGVLKISDFGLSRLHRES-NFQASTNEYAH----TLT--GTLAYLAPEVFGGSYDAFR
 . |. .|     .|  .| .  |.... ||||   | |.| ... ||||||||| . .  .  .|.  | .           .  .|||..   |  | 
RPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI--NYGKFT

A--DIWSMGCIAYVLLTQNFPFGST-----TDPHALEVRIRNGEVSVMPSS--------VSAEAKNLCKWLLSPRPEDRPTLDAVAQHDFF
   |.|| |   . ..|   .  .       ..  .  ....|.    | .         ..|  .. |.     ||||||  ..  |..|
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI--HECF
Kinase LmjF22.0810.AA Pkinase_Tyr 134-154 47 0.00022 15.47 Pfam 141-161 (270) Show / Hide 
Range on Protein: 134-154
Range on HMM: 141-161/270
Sequence Identity: 47% (10 aa)

NLLLGTDGVLKISDFGLSRLH
| |.. ..| ||.||||.|..
NCLVTENNVVKICDFGLARDI
Kinase LmjF22.0810.AA Ciliate-E2a 235-266 34 0.001196 6.64 In-house 244-275 (275) Show / Hide 
Range on Protein: 235-266
Range on HMM: 244-275/275
Sequence Identity: 34% (11 aa)

VSAEAKNLCKWLLSPRPEDRPTLDAVAQHDFF
.| |.|.| | .| . |. |.|     .| .|
CSKECKDLMKKMLEKDPKKRITAQQALNHPWF
Kinase LmjF22.0810.AA Pkinase_Tyr 8-69 22 0.007105 10.36 Pfam 1-70 (270) Show / Hide 
Range on Protein: 8-69
Range on HMM: 1-70/270
Sequence Identity: 22% (16 aa)

YEILDVVGEGAYSKVKRVRHI----PTGCMFVAKIVPKTNQQVE---NDVRLEISILRRL-KHKNIVQLI
 ... . ||||. .|.. .       |..    |... .  . .    |   |..|.. | .|.|||.|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLY