Gene LmjF21.0150 (L.major)

LmjF21.0150

Species: L.major
Alias: LmajK030, LmjF21.0150
External Links:
Annotation:

Classification

Group: CAMK
Family: CAMKL
Subfamily: CAMKL-Unclassified

Sequence

Name Sequence Type Origin Length Description Download
LmjF21.0150.AA Protein None 356 None Fasta, JSON
LmjF21.0150.kin_dom Protein Kinase Domain None 252 None Fasta, JSON

Protein domain

Protein domains of LmjF21.0150.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LmjF21.0150.AA CAMK 167-353 19 4.1e-47 149.43 In-house 181-425 (425) Show / Hide 
Range on Protein: 167-353
Range on HMM: 181-425/425
Sequence Identity: 19% (52 aa)

VKRFMRELLSAVQYLHRTCGLVHRNIKLETLFIDEEQ-----------------HLRLGGFGLCAVLPPPS----------------VVTGDREGALDAP
..|..| ..|||.|.|     ||| .|.| . .|.                    . .  ||. ....| .                .            
ARRYFRQICSAVHYCHSHN-IVHRDLKPENILLDDNNDDSDPVEHDEIFDWNNNNIKIIDFGFANKFDPGENNFMCSDYKGGEMHNQW------------

DAPEDTASSSHEPLRLCCGSKHYAA-PELVQG-------------HPYQGEGVDAWACGVVLFALLTSCFPFDSDDGDEAL---------FRLLCGDVEA
     | . . .... .||. .|.| ||...|             .|| |. .| |.|||.|...|. ..||..|...| .          .|.    ..
-----TTPTEGQKMKTFCGTPEYMAAPEVLNGKGHCNMQNATDEEKPYYGPKCDMWSCGVILYIMLCGYPPFYGDCDNEICEDEWIGMNDYELFEKIMKG

HLA-QHPAMAAI--------ED-----------PQACDLVRNLLRPNPNARYTVSEALEHPYL
     .| .  |         |           ... ||.|..|...|. |.|....|.|| .
KYDFPPPYFSPISCNYGPEWWDDISDEFHHFVSQECKDLIRKMLQVDPEKRMTIEQCLNHPWM
Kinase LmjF21.0150.AA Pkinase 102-353 19 6.2e-40 142.28 Pfam 59-293 (293) Show / Hide 
Range on Protein: 102-353
Range on HMM: 59-293/293
Sequence Identity: 19% (56 aa)

HPHLLPLGAPFASKTDLFVVEKYCAGG----DLYELMVSLAKEDPIASEMGAAKGEAPPRSSTGL--PTNTVKRFMRELLSAVQYLHRTCGLVHRNIKLE
||. . |   | .|... .|  || ||    ||....                      ......  . ...|..|...|....|.|. .| .|| .|.|
HPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--------------------WRHGCFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPE

TLFIDEEQHL----RLGGFGLCAVLPPPSVVTGDREGALDAPDAPEDTASSSHEPLRLCCGSKHYAAPELVQGHPYQGEGVDAWACGVVLFALLTSCFPF
 ..||.. |.    ... |||....                          . . .   ||. .|.|||...|..| |  || |.||..|. .|.  .||
NILIDNNGHIDACVKICDFGLAKQFD-----------------------Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPF

DSD------DGDEALFRLLCGDVEAHLAQHPAMA-------------AIEDPQACDLVRNLLRPNPNARYTVSEALEHPYL
...      | .. ..| ...... .  .   .                 .. ..|.....|...|. |.|  ..|.||..
PGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF
Kinase LmjF21.0150.AA CAMKL 124-353 25 3.3e-38 119.41 In-house 102-297 (297) Show / Hide 
Range on Protein: 124-353
Range on HMM: 102-297/297
Sequence Identity: 25% (62 aa)

YCAGGD--LYELMVSLAKEDPIASEMGAAKGEAPPRSSTGLPTNTVKRFMRELLSAVQYLHRTCGLVHRNIKLETLFIDEEQ--HLRLGGFGLCAV---L
|| ||.  |..  |.  .                      .| .  .|. | ..|||.|.|. .  ||| ||.| . .|| .   . .  ||...     
YCSGGEMDLFDYIVKHGHRR------------------GRMPEHEARRYFRQIVSAVNYCHSHG-IVHRDIKPENILLDENGNNNIKIIDFGFSNMYRPC

PPPSVVTGDREGALDAPDAPEDTASSSHEPLRLCCGSKHYAAPELVQG--HPYQGEGVDAWACGVVLFALLTSCFPFDSD--------DGDEALFRLLCG
                          . . |. .||| .|.|||..||   || |  || |.|||.|.|...  .||| |        .  . . .  ||
-----------------------IFGPGQKLKTFCGSPPYMAPEIFQGNNKPYDGPKVDIWSCGVILYAMVCGYLPFDDDTYNKQGKDNI-YLYWKIMCG

DVEAHLAQHPAMAAIEDPQACDLVRNLLRPNPNARYTVSEALEHPYL
  .     |.      . .. || | .| .||. |.|. . ..|| .
-YYPPIWYHV------S-DCRDLIRKMLQVNPEKRPTIHQIMNHPWM
S_TKc LmjF21.0150.AA S_TKc 68-353 20 3.4e-32 114.19 SMART 18-231 (231) Show / Hide 
Range on Protein: 68-353
Range on HMM: 18-231/231
Sequence Identity: 20% (62 aa)

AKVII--RVYALEYLRRDEECRFALERECLTARLVVHPHLLPLGAPFASKTDLFVVEKYCAG--GDLYELMVSLAKEDPIASEMGAAKGEAPPRSSTGLP
.. .   |..|.  ..    ...  |...|      ||..  |   | . ..|..|  || |  |||......  .. .                  ..|
CRHKKTGRIVAIKIIK----EHIRREIQILKK---HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR----------------FPFP

TNTVKRFMRELLSAVQYLHRTCGLVHRNIKLETLFIDEEQHLRLGGFGLCAVLPPPSVVTGDREGALDAPDAPEDTASSSHEPLRLCCGSKHYAAPELVQ
  .....|.....|..|.|.  | .|| .| | ...||  |. .. |||...|                               . .||. .| |||.. 
E-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------------------------------TTFCGTPWYMAPEVL-

GHPYQGEGVDAWACGVVLFALLTSCFPFDSDDGDEALFRLLCGDVEAHLAQHPAMAAIEDPQACDLVRNLLRPNPNARYTVSEALE-------HPYL
  .| .. .| |.||..|. .|. . ||.    ....|....                 .|.|.|..|..|. .|. |.|. |||.       ||..
--GYGKCKCDWWSCGCILYEMLCGYPPFP---QMQMMFKKIG-----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LmjF21.0150.AA GIN4 247-353 42 1.9e-28 87.67 In-house 191-293 (293) Show / Hide 
Range on Protein: 247-353
Range on HMM: 191-293/293
Sequence Identity: 42% (46 aa)

LRLCCGSKHYAAPELVQGHPYQGEGVDAWACGVVLFALLTSCFPFDSDDGDEALFRLLCGDVEAHLAQHPAMAAIEDPQACDLVRNLLRPNPNARYTVSE
|.  ||| ||||||.| | ||.|   | |.|||.||||||   ||| .||     | |   |     . |.   |   .| ||.| .|   |. | .. .
LETSCGSPHYAAPEIVMGIPYHGFASDVWSCGVILFALLTGHLPFDEEDGN---IRKLLLKVQKGKYEMPSDDEISR-EAQDLIRKILVVDPEKRIKTRD

ALEHPYL
 |.|| .
ILKHPLI
Kinase LmjF21.0150.AA MARK 172-302 31 3.6e-28 89.31 In-house 111-218 (262) Show / Hide 
Range on Protein: 172-302
Range on HMM: 111-218/262
Sequence Identity: 31% (42 aa)

RELLSAVQYLHRTCGLVHRNIKLETLFIDEEQ--HLRLGGFGLCAVLPPPSVVTGDREGALDAPDAPEDTASSSHEPLRLCCGSKHYAAPELVQGHPYQG
| ..|||.|.|.    ||| ||.| . |||.      .  ||...  || .                          |  .||.. |.|||.... || |
RQIVSAVNYCHSKN-IVHRDIKPENILIDENGNHNIKIIDFGFSICIPPGQK-------------------------LNTFCGTPPYMAPEIFLKKPYDG

EGVDAWACGVVLFALLTSCFPFDSDD-GDEALFR
  || |..||||..... .|||| |. ... |..
PKVDIWSLGVVLYFMVCGYFPFDGDTQDYKELYK
Kinase LmjF21.0150.AA Ciliate-E2-Unclassified 102-353 17 1.7e-27 92.44 In-house 80-352 (352) Show / Hide 
Range on Protein: 102-353
Range on HMM: 80-352/352
Sequence Identity: 17% (55 aa)

HPHLLPLGAPFASKTDLFVVEKYCAGGDLYELMVSLAK--EDPIASEMGAAKGEAPPRSSTG-----------LPTNTVK-----RFMRELLSAVQYLHR
||... .   | .|  .. |  || |||| . . .  |  .  .                 .           .. . .|     ......|.. .|||.
HPFIVKMFYCFQDKQNIYIVMEYCEGGDLWQYIKKRKKQKQ--K----------------GNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHH

TCGLVHRNIKLETLFIDEEQ---HLRLGGFGLCA------------VLPPPSVVTGDREGALDAPDAPEDTASSSHEPLRLCCGSKHYA----APELVQG
  . .||.||.| ...|...   .... .||..                                     ..  ... .  .||.  |     |||. ||
KNNIIHRDIKPENILFDNNGKNYYIKIIDFGISKKYQQNNNCDTNQQ---------------------QKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQG

HPYQG---EGVDAWACGVVLFALLTSCFPFDSDDGDE---------------ALFRLLCGDVEAHLAQHP-AMAAIEDPQACDLVR----NLLRPNPNAR
. | .   . .| |..||.|...|.  .||.. . ..                |..  .        . .     . .|.| |...     .|  ||| |
QNYDHSKAYKCDIWSLGVILYEMLFGYYPFYDNNCEQHQQLITQWINNAYRKQLYQNIKQKNIQFPKFPWQQIPKHWSPEAKDFINDLLQKMLKKNPNKR

YTVSEALEHPYL
.| ...|.||..
ITFEQILNHPWF
Kinase LmjF21.0150.AA AMPK 245-353 33 7.6e-27 76.78 In-house 154-254 (254) Show / Hide 
Range on Protein: 245-353
Range on HMM: 154-254/254
Sequence Identity: 33% (37 aa)

EPLRLCCGSKHYAAPELVQGHPYQGEGVDAWACGVVLFALLTSCFPFDSDDGDEALFRLLCGDVEAHLAQHPAMAAIEDPQACDLVRNLLRPNPNARYTV
| |. .|||  |||||...| .| |  || | |||.|.|.|    ||| |.   .|..  .       ....   .   |.| ||....|...|. |.|.
EFLKTACGSPCYAAPEMISGKLYCGPEVDIWSCGVILYAMLCGYLPFD-DENTPTLYKKIK-------NGEYYIPKFLSPEAKDLIKHMLQVDPMKRITI

SEALEHPYL
..  .||..
HDIRNHPWF
Kinase LmjF21.0150.AA Ciliate-E2 124-353 16 7.4e-26 85.73 In-house 115-365 (365) Show / Hide 
Range on Protein: 124-353
Range on HMM: 115-365/365
Sequence Identity: 16% (51 aa)

YCAGGDLYELMVSL-AKEDPIASEMGAAKGEAPPRSSTGLPTNTVKRFMRELLS---------------AVQYLHRTCGLVHRNIKLETLFIDEEQHLRL
|| ||||.... .   |.. . .                .  . .|..|...|.               |..|||     .||.||.| ...     . .
YCQGGDLFDYIKNNKKKRNHEIE----------K-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNNIIHRDIKPENILF-----IKI

GGFGLCAVLPPP-------------------SVVTGDREGALDAPDAPEDTASSSHEPLRL---------CCGSKHYAAPELVQGHPYQG--------EG
  |||.  . ..                   |. .|. .                     .         .||. .| ||| ..| .|..        . 
IDFGLSKKYDDDNQNRTHKQQCKWYMFKNDTSRTPGYMD---------------------QIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYK

VDAWACGVVLFALLTSCFPFDSDDGDEALFRLLCGDVEAHLAQHPAMAAIED-----PQAC-----------------------DLVRN----LLRPNPN
.| |..||.|. .|.  .||                          .  |..     |...                       || ..    .|  .|.
CDIWSLGVILYEMLFGKPPF--------------------------QQQIKQCKIDFPCPEWQKDTQCIQCKWKSWKKWSQECKDLIKKFGKRMLQKDPE

ARYT-VSEALEHPYL
 |.|  ...|.||..
KRITGWEQILNHPWF
Kinase LmjF21.0150.AA MELK 247-353 32 1.4e-19 63.34 In-house 156-254 (254) Show / Hide 
Range on Protein: 247-353
Range on HMM: 156-254/254
Sequence Identity: 32% (35 aa)

LRLCCGSKHYAAPELVQGHPYQGEGVDAWACGVVLFALLTSCFPFDSDDGDEALFRLLCGDVEAHLAQHPAMAAIEDPQACDLVRNLLRPNPNARYTVSE
|  ||||  ||||||.||  | |.  | |. |..|..|.    ||| ||  .....     .     . |   .   |.. .|.|..|  .|. |  . .
LQTCCGSPAYAAPELIQGKQYIGSEADVWSMGILLYVLMCGFLPFD-DDNMMIMYK----KIMSGCYEEPKWLS---PESKQLLRHMLQVDPKKRISMKN

ALEHPYL
 |.||..
LLNHPWV
Kinase LmjF21.0150.AA NuaK 251-295 48 1.5e-18 44.89 In-house 159-203 (252) Show / Hide 
Range on Protein: 251-295
Range on HMM: 159-203/252
Sequence Identity: 48% (22 aa)

CGSKHYAAPELVQGHPYQGEGVDAWACGVVLFALLTSCFPFDSDD
|||  || || | | ||.|  || |. ||.|...     ||| .|
CGSPLYASPEIVNGQPYHGPEVDCWSLGVLLYTMVYGTMPFDGHD
Kinase LmjF21.0150.AA TSSK 251-292 47 3e-18 56.5 In-house 189-230 (289) Show / Hide 
Range on Protein: 251-292
Range on HMM: 189-230/289
Sequence Identity: 47% (20 aa)

CGSKHYAAPELVQGHPYQGEGVDAWACGVVLFALLTSCFPFD
|||. ||||| ..| ||... .| |..||.|..... | |||
CGSYAYAAPEILRGIPYDPKWYDVWSMGVILYIMVCGCMPFD
Kinase LmjF21.0150.AA AMPK 90-212 27 1.3e-12 33.81 In-house 46-146 (254) Show / Hide 
Range on Protein: 90-212
Range on HMM: 46-146/254
Sequence Identity: 27% (34 aa)

LERECLTARLVVHPHLLPLGAPF-ASKTDLFVVEKYCAGGDLYELMVSLAKEDPIASEMGAAKGEAPPRSSTGLPTNTVKRFMRELLSAVQYLHRTCGLV
..||    .|. |||.  |      ..||.|.|  | .||.|..  |.                       . |.    .||.   .|.| |.||  . |
IQREIHILKLFRHPHIIQLYEVIIETPTDIFMVMEYVSGGELFDYIVKH----------------------GRLQEREACRFFQQIISGVEYCHR-HMIV

HRNIKLETLFIDEEQHLRLGGFGL
||  |.| | .|..... .  |||
HRDLKPENLLLDHNKNIKIVDFGL
Kinase LmjF21.0150.AA MELK 168-214 46 2.6e-09 27.67 In-house 100-145 (254) Show / Hide 
Range on Protein: 168-214
Range on HMM: 100-145/254
Sequence Identity: 46% (22 aa)

KRFMRELLSAVQYLHRTCGLVHRNIKLETLFIDEEQHLRLGGFGLCA
. |.|...||. |.|   |  ||..| | |..||. ||.|  |||||
RHFFRQIVSAIAYVH-SQGYAHRDLKPENLLFDEDHHLKLIDFGLCA
Kinase LmjF21.0150.AA NuaK 162-212 35 1.6e-08 17.93 In-house 96-145 (252) Show / Hide 
Range on Protein: 162-212
Range on HMM: 96-145/252
Sequence Identity: 35% (18 aa)

LPTNTVKRFMRELLSAVQYLHRTCGLVHRNIKLETLFIDEEQHLRLGGFGL
|| . ...| |   ||| | |.  . .||  |||    |..   .   |||
LPEREARHFFRQIVSAVHYCHKH-RICHRDLKLENILLDQNCNAKIADFGL
Kinase LmjF21.0150.AA NuaK 325-353 34 3e-06 12.0 In-house 224-252 (252) Show / Hide 
Range on Protein: 325-353
Range on HMM: 224-252/252
Sequence Identity: 34% (10 aa)

QACDLVRNLLRPNPNARYTVSEALEHPYL
.|| |.|..|. ||. | |. .  .|. .
DACMLIRWMLMVNPRRRATIYDICHHWWV
Kinase LmjF21.0150.AA TSSK 328-353 34 4e-06 16.2 In-house 264-289 (289) Show / Hide 
Range on Protein: 328-353
Range on HMM: 264-289/289
Sequence Identity: 34% (9 aa)

DLVRNLLRPNPNARYTVSEALEHPYL
||.| .|.|.|..|... | ..|. .
DLIRHMLQPHPCNRPHINEICHHCWM
Kinase LmjF21.0150.AA MARK 328-353 38 1.2e-05 14.6 In-house 237-262 (262) Show / Hide 
Range on Protein: 328-353
Range on HMM: 237-262/262
Sequence Identity: 38% (10 aa)

DLVRNLLRPNPNARYTVSEALEHPYL
.|.. || .||. | |..| ..|| .
NLIQRLLTVNPEERPTIEEIMKHPWM
Kinase LmjF21.0150.AA GIN4 88-136 28 2.9e-05 12.28 In-house 79-127 (293) Show / Hide 
Range on Protein: 88-136
Range on HMM: 79-127/293
Sequence Identity: 28% (14 aa)

FALERECLTARLVVHPHLLPLGAPFASKTDLFVVEKYCAGGDLYELMVS
. .||| .  .|. ||  . |   .  ..||..|  |  .|.|....|.
YGIEREIVIMKLISHPNVMRLYDVWETNNDLYLVLEYAEKGELFNYLVD
TyrKc LmjF21.0150.AA TyrKc 77-303 10 6.2e-05 -142.84 SMART 1-280 (280) Show / Hide 
Range on Protein: 77-303
Range on HMM: 1-280/280
Sequence Identity: 10% (34 aa)

LEYLR------------------------RDEECRFALERECLTARLV--VHPHLLPLGAPFASK-------TDLFVVEKYCAGGDLYELMVSLAKEDPI
.. ..                        ...  | .. ||    . .   ||... | .   ..         |..|  |...||| .   .  ..   
ITLGKKLGEGAFGEVYKGTWKIQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK---

ASEMGAAKGEAPPRSSTGLPTNTVKRFMRELLSAVQYLHRTCGLVHRNIKLETLFIDEEQHLRLGGFGLCAVLPPP-------SVVT-----GDR-----
                  |.. .   |.    .  .|||.  ...|| .      ..|... . . |||.  .          .. .     | .     
------------------LCMKDLLSFCWQIACGMEYLHSK-NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPI

-------------------------------EGALDAPD------APEDTASSSHEPLRLCCGSKHYAAPELVQGHPYQGEGVDAWACGVVLFALLTSCF
                                |.   |.       ...      .  |. .   .|  | .               |   .. . ..| 
RWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY--P-MS-----------FVCCPDEMYQIMKQCW

PFDSDDG---DEALFRL
 .| .|     |   ..
HEDPEDRPTFSEIHECF
Kinase LmjF21.0150.AA GIN4 162-215 27 0.000795 7.63 In-house 131-184 (293) Show / Hide 
Range on Protein: 162-215
Range on HMM: 131-184/293
Sequence Identity: 27% (15 aa)

LPTNTVKRFMRELLSAVQYLHRTCGLVHRNIKLETLFIDEEQH-LRLGGFGLCAV
||     .. | ..  | | | . ...|| .| | | .|.  . ...  ||. |.
LPEREAIHYFRQIIIGVSYCH-AFNICHRDLKPENLLLDHKYNRIKIADFGMAAL
Kinase LmjF21.0150.AA TSSK 168-195 39 0.007346 5.2 In-house 126-152 (289) Show / Hide 
Range on Protein: 168-195
Range on HMM: 126-152/289
Sequence Identity: 39% (11 aa)

KRFMRELLSAVQYLHRTCGLVHRNIKLE
....| . |||.|.|  .. ||| .|.|
RKWFRQMVSAVKYCH-SHNVVHRDLKCE
Kinase LmjF21.0150.AA MELK 115-136 27 0.210727 0.19 In-house 69-90 (254) Show / Hide 
Range on Protein: 115-136
Range on HMM: 69-90/254
Sequence Identity: 27% (6 aa)

KTDLFVVEKYCAGGDLYELMVS
.  .|.|  ||.||.... ...
EDKIFMVMEYCPGGEMFDYIIR