Gene MLKz_b-2 (S.moellendorffii)

MLKz_b-2

Species: S.moellendorffii
Alias: MLKz_b-2
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: MLKz

Sequence

Name Sequence Type Origin Length Description Download
MLKz_b-2.AA Protein None 607 None Fasta, JSON
MLKz_b-2.NA RNA None 1824 None Fasta, JSON
MLKz_b-2.kin_dom Protein Kinase Domain None 255 None Fasta, JSON

Protein domain

Protein domains of MLKz_b-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MLKz_b-2.AA MLK 315-564 34 1.1e-101 344.09 In-house 1-291 (291) Show / Hide 
Range on Protein: 315-564
Range on HMM: 1-291/291
Sequence Identity: 34% (100 aa)

LKLLHKVASGSFGDLFRGVYCGQD-----VAIKVLKPER----LNEDLQKEFAQEVFIMRKVRHKN----VVQFIGACTKPPN-LSIVTEYMSGGSVYDY
....... |||||. ..|.. ..|     ||.|  . .       .  |..| .|. . |...|.|    ..|| |.|..||. . ||.||..||| |..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHKHRS-------------VLKLPMALRVAIDVSKGMDYLHQNN---IVHRDLKAANLLMDE------NEVVKVADFGVAR-VKDHTGV-MTAETGTYRW
||  ||             | ..  |.. | ....||.|||..    |.|||||  |.| ||      ....|..|||..| .....   |.   |||.|
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYAW

MAPEVI---EHKPYDHKADIFSFGVVLWELLTGKLPYD-YLTPLQAAVAVVQKGLRPVIPKNTHPKLAELMEKCWQSNAAERPEFSIITLVL
||||||   .. .|. |.|..|.||||||.||...||. .. |...|  |...|||| ||..  . ...||..||......|| |. |   |
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase MLKz_b-2.AA TKL 321-564 27 3.7e-96 325.76 In-house 1-364 (364) Show / Hide 
Range on Protein: 321-564
Range on HMM: 1-364/364
Sequence Identity: 27% (103 aa)

VASGSFGDLFRGVYCG----------QDVAIKVLKPERLNEDLQ-------------------------KEFAQEVFIMRKVRHKNVVQFIGACTKPPN-
. ||.||  ..|.. |          .|||.|..| .  .|.                           ... .|. .|.. || |.|||.|.|. ||. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------LSIVTEYMSGGSVYDYLHKHRSVLKLPMALRVAIDVSKGMDYLHQNN--------IVHRDLKAANLLMDENEV--------------V
            | ||.||..||| ..|||       ..  .| |.|...||.|||..|        |.||||| .|.| |||                .
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KVADFGVARVKDHTGVMTA--------------------ETGTYRWMAPEVIEHK----------------PYDHKADIFSFGVVLWELLTGKLPYDYLT
|..||| .|.....| |..                    . ||.|||||||.. .                .|. |.|..|||.||||.||...||. . 
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

PLQAA---------VAVVQKGLRPVIP------------KNTHPKLAELMEKCWQSNAAERPEFSIITLVL
. .           . |..||||| ||            ... | ...||..||.... .|| |. |.  |
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MLKz_b-2.AA Dicty4 315-566 39 1.4e-95 319.21 In-house 1-277 (277) Show / Hide 
Range on Protein: 315-566
Range on HMM: 1-277/277
Sequence Identity: 39% (109 aa)

LKLLHKVASGSFGDLFRGVYCGQDVAIKVL--KPERLNEDLQKEFAQEVFIMRKVRHKNVVQFIGACT----KPPNLSIVTEYMSGGSVYDYLHK-----
..   .  .||||  ..|   |..||.|.|  . . . |.. .||..|| || | || |...| ||||    .|. ..||||||. |..|  ||.     
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-HRSVLKLPMALR---VAIDVSKGMDYLHQ-N-NIVHRDLKAANLLMDENEVVKVADFGVAR----VKDHTGVMTAETGTYRWMAPEVIEHKPYDHKADI
  .  | .|  .|    |.|. .|| .||  | .|.|||||..|||.|.| .|||.||| ..    ..||.  ...  ||  ||||||  |.||. ||| 
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADV

FSFGVVLWELLTGKLPYD--YLTPLQAAVAVVQKGLRPVIPKNTHPKLAELMEKCWQSNAAERPEFSIITLV--LQD
.||| ||||.||.. ||   .  . |.. ||..|.||| ||... |....|...||  .   || |. |.    |  
YSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase MLKz_b-2.AA TKL-Unique 317-564 34 1.8e-90 306.9 In-house 1-290 (290) Show / Hide 
Range on Protein: 317-564
Range on HMM: 1-290/290
Sequence Identity: 34% (101 aa)

LLHKVASGSFGDLFRGVYCGQDVAIKVLKP-ERLNEDLQKEFAQEVFIMRKVR-HKNVVQFIGACT----KPPNLSIVTEYMSGGSVYDYLH-------K
 . |. .|..|  ..|.. | .||||...| | .. .. .||  || .| | . |.|.|...|.|.    .|||..||.||..||| ||.||        
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

HRSVLKLPMALRV--AIDVSKGMDYLHQNN--IVHRDLKAANLLMDEN-----EVVKVADFGVARVKDHTGVMTAE----------TGTYRWMAPEVIEH
 .. .||.|..||  |||...||.||| ..  | |||||  |.| |.|       .|..||| .....    ||.            |..|||||||.. 
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--KPYDHKADIFSFGVVLWELLTGKL------PYDYLTPLQAA--VAVVQKGLRPVIPKNTHPKLAELMEKCWQSNAAERPEFSIITLVL
  . |. |.|..|||.||||..|.|.      ||. ... | .  |... ...|| || .  . . .|...|| ..  .|| |. |   |
NFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase MLKz_b-2.AA TyrKc 315-564 31 7.5e-88 299.09 SMART 1-280 (280) Show / Hide 
Range on Protein: 315-564
Range on HMM: 1-280/280
Sequence Identity: 31% (91 aa)

LKLLHKVASGSFGDLFRGVYCGQDVAIKVLKPERLNEDLQKEFAQEVFIMRKV--RHKNVVQFIGACTKP-------PNLSIVTEYMSGGSVYDYLHKHR
..|..|  .| ||  ..|..  ..||.|.||..      ...| .|  ||.|.  .|.|.|...|.||..       . | ||.|||..|.  |||.|||
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR

SVLKLPMALRVAIDVSKGMDYLHQNNIVHRDLKAANLLMDENEVVKVADFGVARVKDHT-------GVMTA-----ET--GTYRWMAPEVIEHKPYDHKA
  |...  |  ......||.|||..|..|||| | | | .|| .||..||| .|  ..         . ..     .     .||||||.| .. . .| 
PKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DIFSFGVVLWELLT-GKLPYDYL----TPLQAAVAVVQKGLRPVIPKN--------THPKLAELMEKCWQSNAAERPEFSIITLVL
|..||||..||..| |. ||        . | ... |..| |. .|.|         .... ..|..||. ....|| || |   .
DVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase MLKz_b-2.AA Pkinase_Tyr 315-564 33 1.1e-87 297.64 Pfam 1-270 (270) Show / Hide 
Range on Protein: 315-564
Range on HMM: 1-270/270
Sequence Identity: 33% (90 aa)

LKLLHKVASGSFGDLFRGVYC------GQDVAIKVLKPERLNEDL--QKEFAQEVFIMRKV-RHKNVVQFIGACT--KPP-NLSIVTEYMSGGSVYDYLH
.....|  .|.||. ..|..       ...||.|.| .|   ..   ...| .|. ||..  .|.|.|...|.||  . | .. ||.||| .|. .|||.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

KH---RSVLKLPMALRVAIDVSKGMDYLHQNNIVHRDLKAANLLMDENEVVKVADFGVARVKDHTGVM-TAETGTY---RWMAPEVIEHKPYDHKADIFS
||   .  |.... |  .....|||.||...|..|||| | | | .|| |||..||| ||   ...   .. .|.    .|||||.| .. . .| |. |
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWS

FGVVLWELLT-GKLP-YDYLTPLQAAVAVVQKGLRPVIPKNTHPKLAELMEKCWQSNAAERPEFSIITLVL
|||..||..| |. | |  ... .   .. ..| |  .|.|..... .|| .||. ....|| || |   |
FGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase MLKz_b-2.AA DRK 324-566 40 4.2e-86 291.6 In-house 10-258 (258) Show / Hide 
Range on Protein: 324-566
Range on HMM: 10-258/258
Sequence Identity: 40% (100 aa)

GSFGDLFRGVYCGQDVAIKVLKPERLN-EDLQKEFAQEVFIMRKVRHKNVVQFIGACTKPPNLSIVTEYMSGGSVYDYLHKHRSVLKLPMALRVAIDVSK
|..|. |||   |  ||.| |.    | |.. .||..|. .| . || |..||.|.|. ||   |..|||. || |  ||     .  |  .. ..|. |
GNYGEVFRGTWRGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIEMDWPLMKQMMFDCAK

GMDYLHQNN--IVHRDLKAANLLMDENEVVKVADFGVAR----VKDHTGVMTAETGTYRWMAPEVIEHKPYDHKADIFSFGVVLWELLTGKLPYDYLTPL
|| |||  |  |.|||||  ||| ||.  ||||||| .     .|.|.  ||.  ||  | ||||    .|  |||..||..||||..| . ||    ..
GMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTM-CGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVTRQDPYFGMPTF

QAAVAVVQKGLRPVIPKNTHPKLAELMEKCWQSNAAERPEFSIITLVLQD
|   .| . |.|| .|..  || . ||  ||  .   || .  .   |  
QVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase MLKz_b-2.AA TK 315-564 17 5.8e-78 260.78 In-house 1-486 (486) Show / Hide 
Range on Protein: 315-564
Range on HMM: 1-486/486
Sequence Identity: 17% (87 aa)

LKLLHKVASGSFG---DLFRGVYCG---------------------------QDVAIKVLKPE-RLNEDLQKE--------------FAQEVFIMR--KV
..|..|  .| ||   . ..| . |                           ..||.|.||..   ... ...              .|.|  .|.  . 
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

RHKNVVQFIGACTKP------------PNLSIVTEYMSGGS----VYDYLHKHRSV--------------------------------------------
.|.|.|...|.||..            . . ||.|||..|.      |||.|.|                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LKLPMALRVAIDVSKGMDYLHQN------NIVHRDLKAANLLMDENEV-----------VKVADFG---
                               | ..  |  . ....|| |||..      |.||||| | | | .|| |           .|.||||   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----VARVKDHTGVMTAETGTYR---------------------------WMAPEVIE---------HKPYDHKADIFSFGVVLWELLT-G-KLPYDYL
      ||  .. .  .. .. ..                           |||||...         .. . .| |..||||..||..| | . .| ..
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

TP--------LQAAVAVVQKG--------------LRPVIPKNTH--------------PKLAELMEKCWQSNAAERPEFSIITLVL
.         .|  .  ...|              .|.  |.. .              . ...|| .||. ....|| || .   |
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase MLKz_b-2.AA Dicty5 317-568 38 4.5e-73 249.06 In-house 2-260 (260) Show / Hide 
Range on Protein: 317-568
Range on HMM: 2-260/260
Sequence Identity: 38% (101 aa)

LLHKV-ASGSFGDLFRGVYCGQDVAIKVLKPER-LNEDLQKEFAQEVFIMRKVR--HKNVVQFIGACTKPPNL-SIVTEYMSGGSVYDYLHKHRS----V
 .|.. |||. |  . |.| | ||||||. .|  .  |.. ||  || ||  .   | |.. . || ..  .   .|||| . ||. .||   |      
SFHDWIASGASGRVYNGIYKGMDVAIKVYSQENCMCFDWN-EFYREVTIMSIFQSDHPNFIRCYGAHQYNDKYPFHVTEYCHNGSLFNYLNDQRKTTGQP

LKLPMALRVAIDVSKGMDYLHQNNIVHRDLKAANLLMDENEVVKVADFGVARVKDHTGVMTAETGTYRWMAPEVIEHKPYDHKADIFSFGVVLWELLTGK
.  .  |  |||. ..| .||  ||.|||||  | |  ||  .|. |||. |  |    || . ||  |||.|.   .||. |.|..|||.||||..| |
IAYFQQLHMAIDIAQSMRHLHSMNIIHRDLKSMNFLITENWKIKIIDFGTSRFVDNRYHMTMHVGTQCWMACELFNGQPYHQKCDVYSFGIVLWEMFTRK

LPYDYLTPLQAAVAVVQKGLRPVIPKNTHPKLAELMEKCWQSNAAERPEFSIITLVLQDVY
 ||| ..    .|  |.|| || |||      . | .||||     || |  |  ... . 
EPYDNINNWNIPV-MVMKGERPTIPKDCPTEISNLIKKCWQQKPHNRPSFKEICKYFESII
Kinase MLKz_b-2.AA LRRK 310-566 26 4.6e-73 249.03 In-house 1-351 (351) Show / Hide 
Range on Protein: 310-566
Range on HMM: 1-351/351
Sequence Identity: 26% (96 aa)

IDSEQLKLLHKVASGSFG-DLFRGVYCG----------------------------QDVAIKVLKPE----------------------RLNEDLQ----
. .|..     . .|.||   .|. . |                            |.||||... .                        .||      
LKIEEQ-----IGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNH

-------KEFAQEVFIMRKVRHKNVVQFIGACTKPPNLSIVTEYMSGGSVYDYLHKHRS--------VLKLPMALRVAIDVSKGMDYLHQNN--IVHRDL
        || .||.||.. .| |.|. .| | .|  | .|.||.. |. |..||....        ...  . |..|....|||.||| .|  |.||||
EDCCRAFREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDL

KAANLLM---D---------ENEVVKVADFGVAR--VKDHTGVMTAETGTYRWMAPEVIE---HKPYDHKADIFSFGVVLWELLTGK-LPYDYLT-P---
|  | |.   .         .. ..|.||||  |    .|.||    .|. .|||||..     . |. |.|..|||..||||||.. .|.| .. .   
KSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHM

--LQAAVAVVQKGLRPVIPKN-THP-----KLAELMEKCWQSNAAERPEFSIITLVLQD
         ...||||.|| .  .|      . .|...||| .  .|| || |. .| .
QWMEQIEDKIIEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase MLKz_b-2.AA HH498 315-564 30 1.5e-71 226.01 In-house 1-284 (284) Show / Hide 
Range on Protein: 315-564
Range on HMM: 1-284/284
Sequence Identity: 30% (87 aa)

LKLLHKVASGSFGDLFRGVYCGQDVAIKVLKPERLNEDLQ------KEFAQEVFIMRKVRHKNVVQFIGACTK-PPNLSIVTEYMSGGSVYDYL------
.. . |. |||||. ..| . .  ||.|  . .   .           |  || || .  | .||||..||   |  . |||.| ..|| .  |      
IEFHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMAFCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDPSQFAIVTQYCDNGSLFSILNTIPIG

--------HKHR---SVLKLPMALRVAIDVSKGMDYLHQ---NNIVHRDLKAANLLMDENEVVKVADFGVARVKDHTG--VMTAETGTYRWMAPEVIE-H
        |  .    .. |.  .....|| .||.|||      |.||||   | |..|.   .|||||  | .   .   ||   |  |||||||    
GAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMHDDNMTKQPGNLRWMAPEVFSQC

KPYDHKADIFSFGVVLWELLTGKLPYDYLTPLQAAVAVVQKGLRPVIPKN----THPKLAELMEKCWQSNAAERPEFSIITLVL
  |. |.|.||.. ..||..|...|.  . |  ||  .  .  || ||         .   |.  ||. .  .||.|. |  .|
QKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase MLKz_b-2.AA Pkinase 315-555 24 8e-71 246.39 Pfam 1-282 (293) Show / Hide 
Range on Protein: 315-555
Range on HMM: 1-282/293
Sequence Identity: 24% (70 aa)

LKLLHKVASGSFGDLFRGVYCGQD--VAIKVLKPERLNEDLQKEFAQ--EVFIMRKVRHKNVVQFIGACTKPPNLSIVTEYMSGG----SVYDYLH--KH
.... |. |||||  ....  |    ||.|..| .. ... ... .   |. ||....|.|.|....... .... .|.||. ||    . .||..  .|
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

RSV-LKLPMALRVAIDVSKGMDYLHQNNIVHRDLKAANLLMDENEVV----KVADFGVARV--KDHTGVMTAETGTYRWMAPEVIE-HKPYDHKADIFSF
... .    . ...  . .|..|.|...|.||||| .|.|.|.| ..    |..|||.|..    . . ||  .||...||||||  ...|..|.|..|.
GCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GVVLWELLTGKLPYDYL------TPLQAAVAVVQKGLRPVIP-------------------KNTHPKLAELMEKCWQSNAAERP
|..|.|.|.|..|..        ...|  . . .. |.  .|                   .|... . .....|.. . ..||
GCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRP
Kinase MLKz_b-2.AA S_TKc 315-569 25 1.4e-70 241.69 SMART 1-231 (231) Show / Hide 
Range on Protein: 315-569
Range on HMM: 1-231/231
Sequence Identity: 25% (69 aa)

LKLLHKVASGSFGDLFRGVYCG--QDVAIKVLKPERLNEDLQKEFAQEVFIMRKVRHKNVVQFIGACTKPPNLSIVTEYMSG--GSVYDYLHKHRSV---
 ..| |. .|.||  ....  .  . ||||..|         . . .|. |..| .|.|.|......    .| .|.||..|  |...||..|...    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LKLPMALRVAIDVSKGMDYLHQNNIVHRDLKAANLLMDENEVVKVADFGVARVKDHTGVMTAETGTYRWMAPEVIEHKPYDH-KADIFSFGVVLWELL
  .   .| ...  . ....|.|...|.||||| .|.|.||  ..|..|||.||.       |   ||  .|||||.   .|.. |.|. |.|..|.|.|
FPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEML

TGKLPYDYLTPLQAAVAVVQKGLRPVIPKNTHPKLAELMEKCWQSNAAERPEFSIITL----VLQDVYK
.|. |..    .|.   ..             | . ....||.| . ..||    .      . .. . 
CGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MLKz_b-2.AA Dicty4-Unclassified 315-564 32 1.8e-68 233.61 In-house 1-263 (263) Show / Hide 
Range on Protein: 315-564
Range on HMM: 1-263/263
Sequence Identity: 32% (86 aa)

LKLLHKVASGSFGDLFRGVYCGQDVAIKVLKPERLN--EDLQKEFAQEVFIMRKVRHKNVVQFIGACTKP----PNLSIVTEYMSGGSVYDYLH-----K
.. .  .  | |    .|.  | |||.| .   .    |.. ..|  || |.  . | | |.  |.|  |      . ||.| |  |      |     .
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQ

HRSVLKLPM--ALRVAIDVSKGMDYLHQNNIVHRDLKAANLLMDENEVVKVADFGVARVKDHTGVMTAETGTYRWMAPEVIEHKPYDHKADIFSFGVVLW
 .. .||     ...|.|. .|| .||  |..|||.|..|.||| .  .|.||||..|| | .  ||.  || .| .||.  |  |  |.|..|....|.
QQP-IKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLY

ELLTGKLPYDYLT-PLQAAVAVVQKGLRPVIPKNTHPKLAELMEKCWQSNAAERPEFSIITLVL
||.||  ||     .. ||  |  |.||| || |  . .  |   ||      || .  |.  |
ELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL