Gene MLKz_e-1 (S.moellendorffii)

MLKz_e-1

Species: S.moellendorffii
Alias: MLKz_e-1
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: MLKz

Sequence

Name Sequence Type Origin Length Description Download
MLKz_e-1.AA Protein None 435 None Fasta, JSON
MLKz_e-1.NA RNA None 1308 None Fasta, JSON
MLKz_e-1.kin_dom Protein Kinase Domain None 249 None Fasta, JSON

Protein domain

Protein domains of MLKz_e-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase MLKz_e-1.AA TKL 141-391 27 3.7e-90 305.84 In-house 1-364 (364) Show / Hide 
Range on Protein: 141-391
Range on HMM: 1-364/364
Sequence Identity: 27% (103 aa)

FASGAHSRLYHGIYKG----------KAVAVKVMRQPDEDEEVSRMVD---------------------RQFAHEVSLLSRLHHRNIVQFVAACKKPPV-
  ||. .  |.|...|          | ||||.... ..||. . . .                      ..  |. ..|||.| |||||...|. ||  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------YCVVTEYLAGGSLRGFLHKNEPSSLPLKVTLGMAMDIARGMEYIHSQR--------VIHGDLKSENLVLDGDMC--------------
            .| |.||  ||||. .||        . ... .|.||||||.| ||..        .|| ||||.|. .| ..               
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

VKITDFGVARCEADAPSVGKAD-------------------VGTYRWMAPEMISGKN---------------KCSTKVDVYSFGIVLWELVTGQVPFQEM
.||.||| .|.     .  .                     .||.||||||.. |..               . |.|.|||||||||||..|...|....
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDY

QAVQVA---------YAVLHKDARPEVP------------ENCPSALAALMRRCWSANPDKRPGFPEIVKTL
   ..          . | .|  ||..|            ..||  .. || .||...|.||| | ||.|.|
PYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase MLKz_e-1.AA TKL-Unique 137-391 32 7.2e-87 294.91 In-house 1-290 (290) Show / Hide 
Range on Protein: 137-391
Range on HMM: 1-290/290
Sequence Identity: 32% (97 aa)

LGHKFASGAHSRLYHGIYKGKAVAVKVMR-QPDEDEEVSRMVDRQFAHEVSLLSRLH-HRNIVQFVAACK----KPPVYCVVTEYLAGGSLRGFLHK---
 . |  .|. .. |.|...|. ||.|.   .    |..|  . . |  ||.....|| | |||.....|.    .|| .| |.||. ||||.  ||    
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPN----EDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNN

-----NEPSSLPLKVTLGMAMDIARGMEYIHSQR--VIHGDLKSENLVLDGD-----MCVKITDFGVARCEA--DAPSVG-------KADVGTYRWMAPE
     |. . |.... . || |||.||.|.|.    .||.|||| |. .| .     . .|| ||| ..  .  .. ...          .|..||||||
NNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPE

MISGK-NKCSTKVDVYSFGIVLWELVTGQV------PFQEMQAVQVAYAVLH--KDARPEVPENCPSALAALMRRCWSANPDKRPGFPEIVKTL
....  .. |.|.|||||||||||..|...      |.|.|   |.. .|    .  ||..|..||  .  |...||  .|..|| | ||.. |
VLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase MLKz_e-1.AA MLK 135-391 32 4.3e-84 285.69 In-house 1-291 (291) Show / Hide 
Range on Protein: 135-391
Range on HMM: 1-291/291
Sequence Identity: 32% (97 aa)

LFLGHKFASGAHSRLYHGIYKGKA-----VAVKVMR-QPDEDEEVSRMVDRQFAHEVSLLSRLHHRN----IVQFVAACKKPPV-YCVVTEYLAGGSLRG
. . ..  ||.    . | ...|      ||||  |  .. |  ..   ...|  |. .|..| |.|    |.||...|..||  .|.|.||..||||  
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

FLHKNEP------------SSLPLKVTLGMAMDIARGMEYIHS-QR--VIHGDLKSENLVLD------GDMCVKITDFGVAR--CEA-D-APSVGKADVG
.|| ...               .. . .  |...||||.| || ..  .|| |||| |...|      ... .||.|||..|  ..  .  .|      |
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSN----AG

TYRWMAPEMI--SGKNKCSTKVDVYSFGIVLWELVTGQVPFQ-EMQAVQVAYAVLHKDARPEVPENCPSALAALMRRCWSANPDKRPGFPEIVKTL
||.|||||.|  .  .|.| |.||.|.|.||||..|..||.. .. . ..|. | ..  || .| .||  .. || .||...| ||| | .||. |
TYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase MLKz_e-1.AA TyrKc 135-391 31 3.6e-78 266.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 135-391
Range on HMM: 1-280/280
Sequence Identity: 31% (91 aa)

LFLGHKFASGAHSRLYHGIYKGKAVAVKVMRQPDEDEEVSRMVDRQFAHEVSLLSRL--HHRNIVQFVAACKKP-------PVYCVVTEYLAGGSLRGFL
. ||.|  .||  . |.|..|   ||||...             . | .| .....|  || |||.....| ..       . ...|.|| ..|.|. .|
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYL

HKNEPSSLPLKVTLGMAMDIARGMEYIHSQRVIHGDLKSENLVLDGDMCVKITDFGVARCEADA-------PSVGK-----AD-VGTYRWMAPEMISGKN
.|..|  |..|  | .. .||.||||.||...|| ||   |  .. . .|||.||| .|   |            |     .. .  .|||||| |  ..
RKHRPK-LCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI-NYG

KCSTKVDVYSFGIVLWELVT-GQVPFQEM----QAVQVAYAVLHKDARPEVPEN--------CPSALAALMRRCWSANPDKRPGFPEIVKTL
|..|| ||.|||...||. | || |  .|       | ... . .  |.. |.|        ||...  .|..|| ..|..|| | ||.. .
KFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase MLKz_e-1.AA Dicty4 143-393 35 1.3e-73 244.85 In-house 9-277 (277) Show / Hide 
Range on Protein: 143-393
Range on HMM: 9-277/277
Sequence Identity: 35% (97 aa)

SGAHSRLYHGIYKGKAVAVKVMRQPDEDEEVSRMVDRQFAHEVSLLSRLHHRNIVQFVAACK----KPPVYCVVTEYLAGGSLRGFLHK-------NEPS
.|. .  | |. .||.||||..    .. . ... .  |..||.... . | ||..|  ||     .|.  | ||||.  |.|   ||.       . ..
KGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNE--FRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKL

SLPLKVT-LGMAMDIARGMEYIHS--QRVIHGDLKSENLVLDGDMCVKITDFGVAR---CEADAPSVGKADVGTYRWMAPEMISGKNKCSTKVDVYSFGI
..||    . || |.|||| . |.   ..|| |||| ||  | .. ||..||| ..    . |     .. .||  |||||.  . .    |.|||||||
DWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMH-QPYNEKADVYSFGI

VLWELVTGQVPFQ--EMQAVQVAYAVLHKDARPEVPENCPSALAALMRRCWSANPDKRPGFPEIVKT--LEQ
||||..|.| |.|   |  .|.. ||  |  ||..| .||  ...|. .||. .| .|| |.||..   || 
VLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase MLKz_e-1.AA Pkinase_Tyr 150-391 33 4.2e-73 248.21 Pfam 16-270 (270) Show / Hide 
Range on Protein: 150-391
Range on HMM: 16-270/270
Sequence Identity: 33% (88 aa)

YHGIYK------GKAVAVKVMRQPDEDEEVSRMVDRQFAHEVSLLSRL-HHRNIVQFVAACK--KPP-VYCVVTEYLAGGSLRGFLHKN--EPSSLPLKV
|.|..|      .  ||||....   .|.      . | .|..... | || |||.....|   . |  ...|.|| ..|.|. .|.|.  .. .|..| 
YKGTWKGDPDNTKIPVAVKMLKEGAMHEQN---CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHREDKQPLTMKD

TLGMAMDIARGMEYIHSQRVIHGDLKSENLVLDGDMCVKITDFGVARCE--ADAP-SVGKADVGTYRWMAPEMISGKNKCSTKVDVYSFGIVLWELVT-G
 |.|...||.|||| .|.. || ||   |  .. ...|||.||| ||     |    ...      .||||| |.  .|..|| ||.|||...||..| |
LLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECIN-YGKFTTKSDVWSFGVLMWEIFTYG

QVP-FQEMQAVQVAYAVLHKDARPEVPENCPSALAALMRRCWSANPDKRPGFPEIVKTL
. | ...|   .|  ..  .  | . |||||  .  ||..|| ..|..|| | ||.  |
EQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase MLKz_e-1.AA TK 135-391 18 3.9e-71 237.5 In-house 1-486 (486) Show / Hide 
Range on Protein: 135-391
Range on HMM: 1-486/486
Sequence Identity: 18% (91 aa)

LFLGHKFASGAHS---RLYHGIYKGK---------------------------AVAVKVMR---QPDEDEEVSRMVDR--------QFAHEVSLLS--RL
. ||.|  .|.     . | |...|.                            ||||...     ...|.  .. ..        ..|.| ....   .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHRNIVQFVAACKKP------------PVYCVVTEYLAGGS----LRGFLHKNEP---------------------------------------------
|| |||.....| ..            . ...|.|| ..|.    || .|.|. |                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

---------SSLPLKVTLG-------------------MAMDIARGMEYIHSQ------RVIHGDLKSENLVLDGDMC-----------VKITDFG----
         ..|..|  |                    |...||.||||.||.      ...|.||   |  .. ..            .||.|||    
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----VARCE-ADAPSVGKADVGT-------------------------YRWMAPEMISG--------KNKCSTKVDVYSFGIVLWELVT-GQVPFQEMQA
     ||    |   . | . ||                          |||||| . .        ..|..|| ||.|||...||..| ||.|. ..  
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGMS

V---------QVAYAVLHKD--------------ARPEVPENCP--------------SALAALMRRCWSANPDKRPGFPEIVKTL
          |  .  | .                |.. |..||               ... ||..||...|..|| | .... |
NQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase MLKz_e-1.AA LRRK 179-393 36 7.8e-67 228.35 In-house 102-351 (351) Show / Hide 
Range on Protein: 179-393
Range on HMM: 102-351/351
Sequence Identity: 36% (92 aa)

RQFAHEVSLLSRLHHRNIVQFVAACKKPPVYCVVTEYLAGGSLRGFLHKNEPSS-------LPLKVTLGMAMDIARGMEYIHSQR--VIHGDLKSENLVL
| | |||...|.|.| |||. .  | .|  .| |.||.  |.|  |||... ..       ..  ..|  |..||.|||| ||..  .|| ||||.|  |
REFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

---D---------GDMCVKITDFGVAR-CEADAPSVGKADVGTYRWMAPEMIS--GKNKCSTKVDVYSFGIVLWELVTGQ-VPFQEMQ-------AVQVA
   .          ..|.|| |||  |   .. ..| |  ||. .||||| .   |.  ...|||.||||..||||.|.|  ||.|..         |. 
WSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIE

YAVLHKDARPEVPEN-CPS-----ALAALMRRCWSANPDKRPGFPEIVKTLEQ
 ... .  || .|.. ||       . .|.  ||...|.||| | .|||.|.|
DKII-EGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase MLKz_e-1.AA MLK 135-391 34 5.3e-66 217.07 In-house 1-280 (280) Show / Hide 
Range on Protein: 135-391
Range on HMM: 1-280/280
Sequence Identity: 34% (98 aa)

LFLGHKFASGAHSRLYHGIYKGKAVAVKVMRQPDEDEEVSRM--VDRQFAHEVSLLSRLHHRNIVQFVAACKKPPVYCVVTEYLAGGSLRGFLHKNEPSS
| .     .|   . | . .||. ||||  || | .. ....     |   |  |.  |.| ||..  ..| ..|  | | || .||||.  .       
LKIKEIIGNGGFGKVYRAQWKGEEVAVKAHRQ-DPEQDMQQTDEQAEQVRQEARLFWMLKHPNIIALRGVCLEDPHLCLVMEYCRGGSLNRVCAGK---R

LPLKVTLGMAMDIARGMEYIHSQR---VIHGDLKSENLVLDGDMC-------------------------VKITDFGVARCEADAPSVGKADVGTYRWMA
 |..|    |. |||||.|.| .    .|| ||||.|  .    |                          ||||||.||          |  ||| |||
IPPHVLVNWAVQIARGMNYLHNEAPVPIIHRDLKSSNILILEKICLCMDEEMFQYAYCLKCGHHDMCNKQLKITDFGLAREWHKTTRMSAA--GTYAWMA

PEMISGKNKCSTKVDVYSFGIVLWELVTGQVPFQEMQAVQVAYAVLHKDARPEVPENCPSALAALMRRCWSANPDKRPGFPEIVKTL
|| |. .   |   || |.|..||||.|| ||.... .. ||| |  .     .|. ||   |.||. ||  .| |||.| ||.. |
PEVIK-ESTWSKGSDVWSYGVLLWELLTGEVPYRGIDPLAVAYGVAMNKLTLPIPSTCPEPWAKLMQDCWNQDPHKRPKFSEILQQL
Kinase MLKz_e-1.AA DRK 181-393 37 2.8e-63 213.15 In-house 44-258 (258) Show / Hide 
Range on Protein: 181-393
Range on HMM: 44-258/258
Sequence Identity: 37% (82 aa)

FAHEVSLLSRLHHRNIVQFVAACKKPPVYCVVTEYLAGGSLRGFLHKNEPSSLPLKVTLGMAMDIARGMEYIHSQR--VIHGDLKSENLVLDGDMCVKIT
|. |. |...| | ||.||  .|  ||  |...||.  |||   || .|  ..     . |..|.|.|| | |.    .|| |||| ||  |    ||. 
FHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILH-DESIEMDWPLMKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVDEHWQVKVA

DFGVAR--CEADAPSVGKADVGTYRWMAPEMISGKNKCSTKVDVYSFGIVLWELVTGQVPFQEMQAVQVAYAVLHKDARPEVPENCPSALAALMRRCWSA
||| .            .  .||  | |||          | |||||.|||||.|| | |.. |   ||  .|     || .|..||   ..|| .||. 
DFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLR-NQRYTEKADVYSFAIVLWECVTRQDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNE

NPDKRPGFPEIVKTLEQ
.|  || ..|... || 
DPQHRPSMQECLERLEA
Kinase MLKz_e-1.AA S_TKc 135-394 24 4.6e-63 216.73 SMART 1-231 (231) Show / Hide 
Range on Protein: 135-394
Range on HMM: 1-231/231
Sequence Identity: 24% (67 aa)

LFLGHKFASGAHSRLYHGIYKG--KAVAVKVMRQPDEDEEVSRMVDRQFAHEVSLLSRLHHRNIVQFVAACKKPPVYCVVTEYLAG--GSLRGFLHKNEP
  .. |  .|| .. | .. |.  . ||.|...             ...  |...|.. || |||..  ..     ...|.||. |  |.|. ...|. .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGR

----SSLPLKVTLGMAMDIARGMEYIHSQRVIHGDLKSENLVLDGDMCVKITDFGVARCEADAPSVGKADVGTYRWMAPEMISGKNKCST-KVDVYSFGI
    . .|  ..  ..  |....||.||...|| ||| ||. ||   ..||.|||.||         .  .||  .||||..    . .. |.|..|.|.
HGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGC

VLWELVTGQVPFQEMQAVQVAYAVLHKDARPEVPENCPSALAALMRRCWSANPDKRPGFPEIVK------TLEQL
.|.|...|. ||.    .|. . ..            .. .  ..|.|.  .|.|||.  |. .        . .
ILYEMLCGYPPFP---QMQMMFKKIG-----------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase MLKz_e-1.AA UTK 158-391 30 1.5e-61 209.36 In-house 31-296 (296) Show / Hide 
Range on Protein: 158-391
Range on HMM: 31-296/296
Sequence Identity: 30% (83 aa)

AVAVKVMRQPDEDEEVSRMVDR---QFAHEVS---LLSRLH-HRNIVQFVAACKKPPVYCVVTEYLAGGSLRGFLHKNEPS------SLPLKVTLGMAMD
.||||| .     .....   .   .|  |     .....| |.|....|. | .    ..|||| ..|.|| .| .. |.      .| |   |.||.|
DVAVKVCQ----HHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYMENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWD

IARGMEYIHSQRVIHGDLKSENLVLDGD-------MCVKITDFG---VARCEA---------DAPSVGKADVGT--YRWMAPEMISGKNKCSTKVDVYSF
|||||.|.||....|.||   |  .. .       | .|| |||    .|  .         ... . .....    |||||| .    . .|| ||.||
IARGMQYLHSCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWESYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSF

GIVLWELVT-GQVPFQEMQAVQVAYAVLHKD-ARPEVPENCPSALAALMRRCWSANPDKRPGFPEIVKTL
|.|.||..| |..|. .| ..||. .|. .. .|.. |. || ..  ||.||| ..|..|| |...|...
GVVCWEIWTWGRLPYPGMSNMQVWHQVCNGGRYRMPCPWDCPHPVYRLMHRCWHYDPQERPDFEDLVQQM
Kinase MLKz_e-1.AA Dicty4-Unclassified 135-391 32 1.4e-60 206.18 In-house 1-263 (263) Show / Hide 
Range on Protein: 135-391
Range on HMM: 1-263/263
Sequence Identity: 32% (87 aa)

LFLGHKFASGAHSRLYHGIYKGKAVAVKVMRQPDEDEEVSR--MVDRQFAHEVSLLSRLHHRNIVQFVAACKKP----PVYCVVTEYLAGGSLRGFLH--
.        |. |. . |. ||| |||| .    |     |  |..  |  || .|  . | | |.   .|  |      .|.|.| .  | |    |  
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKF---NENKFKFREEMIQ-DFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSK

---KNEPSSLPLKVTLGMAMDIARGMEYIHSQRVIHGDLKSENLVLDGDMCVKITDFGVARCEADAPSVGKADVGTYRWMAPEMISGKNKCSTKVDVYSF
   .. | .|   . . .|.|||.|| . |.  .|| |.|| |. .| .  .|| |||..| . |      .  || .| .||   .    . | ||||.
PSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFNIKIADFGISR-VIDFNFNMTTIAGTPKWESPECLMHESYNQ-KSDVYSY

GIVLWELVTGQVPFQEMQ-AVQVAYAVLHKDARPEVPENCPSALAALMRRCWSANPDKRPGFPEIVKTL
...|.||.||  |.|| |  . .|  |  |  ||..|.||.  .  |   ||.  | ||| . .|.. |
AMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase MLKz_e-1.AA Pkinase 135-391 24 3.2e-56 197.91 Pfam 1-293 (293) Show / Hide 
Range on Protein: 135-391
Range on HMM: 1-293/293
Sequence Identity: 24% (74 aa)

LFLGHKFASGAHSRLYHGIYKGKA--VAVKVMRQPDEDEEVSRMVDRQFAHEVSLLSRLHHRNIVQFVAACKKPPVYCVVTEYLAGG----SLRGFLH--
. .| |  ||. .. |... ||    ||||... ..|.... .   |    |.... ||.| |||..  ..  .. ...|.||. ||    .|  ...  
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL--SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

-KNEPSSLPLKVTLGMAMDIARGMEYIHSQRVIHGDLKSENLVLDGDMCV----KITDFGVARC--EADAPSVGKADVGTYRWMAPEMISGKNKCSTKVD
 ..  . .. ..   ..  |.||.||.||...|| |||.||. .| .. .    ||.|||.|..  .   .   .  .||...|||| | | .. ..|||
RHGCFY-FSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS--MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSFGIVLWELVTGQVPFQEM------QAVQVAYAVLHKDARPEVPENCP-------------------SALAALMRRCWSANPDKRPGFPEIVKT--L
..|.|..|.|...|. ||..          |. . ..... . . |. |.                   ...  ....|.  .| |||....|..   .
MWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHPWF