Gene LZK_b-1 (S.moellendorffii)

LZK_b-1

Species: S.moellendorffii
Alias: LZK_b-1
External Links:
Annotation:

Classification

Group: TKL
Family: MLK
Subfamily: LZK

Sequence

Name Sequence Type Origin Length Description Download
LZK_b-1.AA Protein None 1023 None Fasta, JSON
LZK_b-1.NA RNA None 3072 None Fasta, JSON
LZK_b-1.kin_dom Protein Kinase Domain None 264 None Fasta, JSON

Protein domain

Protein domains of LZK_b-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
PB1 LZK_b-1.AA PB1 43-130 40 4.2e-29 103.94 SMART 1-95 (95) Show / Hide 
Range on Protein: 43-130
Range on HMM: 1-95/95
Sequence Identity: 40% (39 aa)

PSDGRLRYAGGDTRMIAVTRDTSYLNLMLKMVEIQPQ----TVAIKYQLPDEDLDALVSVSSEEDLENMMEEFDKLEAGD----GHARLRVFLFTS
| |...|| ||||| ..| ||.|.  || |. .. ..    .. .||||||||.||.|.....|||..|||. |.||.      . ..||...| .
PVDVKCRYVGGDTRRFSVPRDWSFDDLMSKVAQRCGHDNDQPFTLKYQLPDEDGDAWVTITCDEDLQEMMEMYDSLES-QNKSSCWKTLRLHVFPF
PB1 LZK_b-1.AA PB1 43-130 35 1.3e-22 82.86 Pfam 1-86 (86) Show / Hide 
Range on Protein: 43-130
Range on HMM: 1-86/86
Sequence Identity: 35% (32 aa)

PSDGRLRYAGGDTR-MIAVTRDTSYLNLMLKMVEIQPQTVAIKYQLPDEDLDALVSVSSEEDLENMMEEFDKLEAGDGHARLRVFLFTS
. ....|| |...|  | | |..|.  || |. .. .. . .|||.||||.|..|.....|||..|||| ...|   ....||...| |
TVRIKCRYGGDIRRFIIHVRRNISFEDLMHKVEQRCKCDHTFKYQYPDEDGDDWVTITCDEDLQEMMEEYRSSE---KSMTLRLHVFPS
Kinase LZK_b-1.AA TKL 723-980 28 5.4e-83 282.04 In-house 1-364 (364) Show / Hide 
Range on Protein: 723-980
Range on HMM: 1-364/364
Sequence Identity: 28% (105 aa)

LGSGTFGTVYHGKWRG----------TDVAIKRIKASCFFGPPS-------------------EQDRLKDDFWSEACILAHLHHPNVVAFYGVVPDSPGG
.|||.||.||.|||||          .|||.|..|        .                   |. .... .  |. ..  |.|||.| |.|.. ..|.|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

T-----------LATVTEFMVNGSLKQVLHKKERILDRRRRLLVAMDAAFGMEYLHD--------KKIIHFDLKGENLLVN--MR-------DSQKPV-C
.           |. |.|.. .|||  .||         .|.  |.|.| ||.|||         ..||| ||| .|.||.  ..       . .... |
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCC

KVGDLGLSKIKHKTM--------------------VTGGVRGTLPWMAPELLNGR--------------SISVSEKVDVFSFGIVMWELLTGEEPYADLH
|..|.|||. .....                     |. ..||. |||||.|.|               . . |||.||.|||||.||.||...||.|..
KICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYP

YG---------AIIGGIVSNQLRPQVP------------SSCDPEWQSLMERCWADDPAVRPTFPAIVGEL
|          ... ......||| .|            ..|.|.. .||..||. ||  ||.|  |. .|
YMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LZK_b-1.AA MLK 717-980 36 2.3e-81 276.61 In-house 1-291 (291) Show / Hide 
Range on Protein: 717-980
Range on HMM: 1-291/291
Sequence Identity: 36% (107 aa)

LEEIRELGSGTFGTVYHGKWRGTD-----VAIKRIKASCFFGPPSEQDRLKDDFWSEACILAHLHHPN----VVAFYGVVPDSPGGTLATVTEFMVNGSL
... . .|||.|| |. |.||..|     ||.||..|. |    |. .  ..||  |. .|..| |||    ...||||  ..|   .. |.|.. .|||
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF--DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPP-CHFCIVMEYCEGGSL

KQVLHKKE-------------RILDRRRRLLVAMDAAFGMEYLHDKK---IIHFDLKGENLLVN---MRDSQKPVCKVGDLGLSKIKHKT---MVTGGVR
  ||| ..             |. |    .  |.. | ||.||| ..   |||.|||  |.|.      | .. ..|. | |.|. .|..   |   . .
YNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICH-DMHHGTLKICDFGTSRDWHQMCTNMM--SNA

GTLPWMAPELLNG-RSISVSEKVDVFSFGIVMWELLTGEEPYA-DLHYGAIIGGIVSNQLRPQVPSSCDPEWQSLMERCWADDPAVRPTFPAIVGEL
||. ||||| .   |.  .|||.||.|.|.|.||.||.|.||. ..   ||. ... | ||| .||.|.. | .||..|| .||. ||.|  || .|
GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYKQHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKRPSFRQIVQHL
Kinase LZK_b-1.AA Pkinase_Tyr 717-980 34 1.5e-70 239.56 Pfam 1-270 (270) Show / Hide 
Range on Protein: 717-980
Range on HMM: 1-270/270
Sequence Identity: 34% (98 aa)

LEEIRELGSGTFGTVYHGKWR------GTDVAIKRIKASCFFGPPSEQDRLKDDFWSEACILAHL-HHPNVVAFYGVVP--DSPGGTLATVTEFMVNGSL
.. ...||.| ||.||.|.|.      ...||.| .|     |  .||  ...|| .|| |. .| ||||.| .|||.   . |.  .  |.|.| .|.|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKE----GAMHEQN-CREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPN-QIYIVMEYMPHGDL

KQVLHKK---ERILDRRRRLLVAMDAAFGMEYLHDKKIIHFDLKGENLLVNMRDSQKPVCKVGDLGLSKIK-----HKTMVTGGVRGTLPWMAPELLNGR
.  |.|.   .. |.  . |  ... | |||||..|..|| ||   | ||.     . |.|..| ||..         . ..|| .   .||||| .| .
LDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLESKNCIHRDLAARNCLVTE----NNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYG

SISVSEKVDVFSFGIVMWELLT-GEEP-YADLHYGAIIGGIVSNQLRPQVPSSCDPEWQSLMERCWADDPAVRPTFPAIVGEL
    ..| || |||..|||..| ||.| |...    ..  |  .  |   |  | .|  .|| .||. ||. |||| .|. .|
K--FTTKSDVWSFGVLMWEIFTYGEQPTYPGMSNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase LZK_b-1.AA Dicty4 717-982 34 6.9e-70 232.29 In-house 1-277 (277) Show / Hide 
Range on Protein: 717-982
Range on HMM: 1-277/277
Sequence Identity: 34% (101 aa)

LEEIRELGSGTFGTVYHGKWRGTDVAIKRI---KASCFFGPPSEQDRLKDDFWSEACILAHLHHPNVVAFYG--VVPDSPGGTLATVTEFMVNGSLKQVL
.    ..|.| ||.|| |.|||..||.|     .        .....|. .|  |. |.. . |||.. |.|    | |  |..  |||.|  |.|  .|
INIEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQN------FDENMLN-EFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLL

HK------KERILD--RRRR-LLVAMDAAFGMEYLHD--KKIIHFDLKGENLLVNMRDSQKPVCKVGDLGLSK----IKHKTMVTGGVRGTLPWMAPELL
|.      ..  ||  ...| .. | ||| || .||     ||| |||  ||||    ..  . ||.|.|||.    .. ..  . .. ||  ||||| .
HDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPVIIHRDLKSHNLLV----DKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVM

NGRSISVSEKVDVFSFGIVMWELLTGEEPYA--DLHYGAIIGGIVSNQLRPQVPSSCDPEWQSLMERCWADDPAVRPTFPAIVGE--LRS
  .. .  ||.||.||||| ||.||..|||.     |  .. .... .||| .|..|.| | .|...||  || .||.|. |. .  | .
--MHQPYNEKADVYSFGIVLWEILTRQEPYQKHHMPYMQFVRAVCNKKLRPPIPDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase LZK_b-1.AA TyrKc 717-980 31 1.1e-67 232.05 SMART 1-280 (280) Show / Hide 
Range on Protein: 717-980
Range on HMM: 1-280/280
Sequence Identity: 31% (93 aa)

LEEIRELGSGTFGTVYHGKWRGTDVAIKRIKASCFFGPPSEQDRLKDDFWSEACILAHL--HHPNVVAFYGVVPDSPG-----GTLATVTEFMVNGSLKQ
.. ...||.| ||.||.|.|. ..||.| .|...           . || .|| |. .|  ||||.|..|||. .. .     . |  |.|.| .|.||.
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDA-----------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKD

VLHKKERILDRRRRLLVAMDAAFGMEYLHDKKIIHFDLKGENLLVNMRDSQKPVCKVGDLGLSKIKHKT--------MVTG----GVR--GTLPWMAPEL
 |.|... |  .  |  . ..| ||||||.|..|| ||   | ||. .     ..|..| |||.  .          . .     | .    . ||||| 
YLRKHRPKLCMKDLLSFCWQIACGMEYLHSKNCIHRDLAARNCLVGENH----TVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPEC

LNGRSISVSEKVDVFSFGIVMWELLT-GEEPYAD-----LHYGAIIGGIVSNQLRPQVPS-------SCDPEWQSLMERCWADDPAVRPTFPAIVGEL
.  .    ..| ||.|||..|||..| |..|| .     .    .|  . .   .|| |.        | .|  ..|..||. ||. |||| .|. ..
I--NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LZK_b-1.AA TKL-Unique 720-980 32 3.7e-66 226.1 In-house 2-290 (290) Show / Hide 
Range on Protein: 720-980
Range on HMM: 2-290/290
Sequence Identity: 32% (97 aa)

IRELGSGTFGTVYHGKWRGTDVAIKRIKASCFFGPP-SEQD-RLKDDFWSEACILAHLH-HPNVVAFYGVVPD---SPGGTLATVTEFMVNGSLKQVLH-
.  .|.|..|.||.|||||..||||...       | ...  .....| .|  ..  || |||.| ..|.  |   .|.  .  |.|..  |||  ||| 
WNKIGEGGYGQVYKGKWRGYPVAIKQFH-------PNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPP-NMCIVMEYCPGGSLYDVLHQ

--------KKERILDRRRRLLVAMDAAFGMEYLHDKK--IIHFDLKGENLLVNMR-DSQKPVCKVGDLGLSKIKH--KTMVTG--------GVRGTLPWM
        ...  |.  .|.  | |.| ||.||| ..  |||.|||  |.||. .  . .   |. | ||||..    .| ..        .. |.. ||
NNNNNNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWM

APELLNGRSISVSEKVDVFSFGIVMWELLTGEE------PYADLHYGAIIGGIVS--NQLRPQVPSSCDPEWQSLMERCWADDPAVRPTFPAIVGEL
|||.|..     |||.||.|||||.||..|..       || ..   ...  . .    .|| .|..| .| . |...||..||  ||.|  |. .|
APEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKPYQGMDQEQWCEMVHYMEENYRPPIPNHCPKEYRDLIQQCWHHDPSQRPSFDEIIHRL
Kinase LZK_b-1.AA TK 717-980 20 7.2e-66 219.52 In-house 1-486 (486) Show / Hide 
Range on Protein: 717-980
Range on HMM: 1-486/486
Sequence Identity: 20% (99 aa)

LEEIRELGSGTFG---TVYHGKWRG---------------------------TDVAIKRIKASCFFGPPSEQDRLKDD---------FWSEACILAH--L
.. ...||.| ||   .|| |.|||                           |.||.| .|. .   .  ..|.  .|         ...|.... |  .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

HHPNVVAFYGVVPDSPG----------GTLATVTEFMVNGS----LKQVLHKKER---------------------------------------------
||||.| .|||. .. .          . .  |.|.| .|.    |.. |.|. .                                             
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------ILDRRRRLLVAMDAAFGMEYLHDK------KIIHFDLKGENLLVNMRDSQK-------PVCKVGDLG---
                              .|. ...|  ....| ||||||.|      ...| ||   | ||. ..  |       ||||..| |   
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----LSKIKHK--TMVTGGVRGT-------------------------LPWMAPELLNGRSIS-------VSEKVDVFSFGIVMWELLT-GEEPYADLH
     |..  ..    .. . .||                         . ||||| ||.|  |        ..| ||.|||..|||..| |.|||.  .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYGGM

YG---------AIIGGIVSNQ--------------LRPQVPSSCD--------------PEWQSLMERCWADDPAVRPTFPAIVGEL
           . .   . .               .|.  |  |               .|.. || .||. ||. |||| ... .|
SNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LZK_b-1.AA S_TKc 717-988 25 2.6e-60 207.57 SMART 1-231 (231) Show / Hide 
Range on Protein: 717-988
Range on HMM: 1-231/231
Sequence Identity: 25% (73 aa)

LEEIRELGSGTFGTVYHGKWRG--TDVAIKRIKASCFFGPPSEQDRLKDDFWSEACILAHLHHPNVVAFYGVVPDSPGGTLATVTEFMVN--GSLKQVLH
 | .|..|.|.||.|| .....    ||||.||               .....|  || . ||||.| .|.|  |   . |  |.|.. .  |.|.....
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------------EHIRREIQILKK-HHPNIVKLYDVFQD---DHLYMVMEYCDGDLGDLFDYIK

KKERI-----LDRRRRLLVAMDAAFGMEYLHDKKIIHFDLKGENLLVNMRDSQKPVCKVGDLGLSKIKHKTMVTGGVRGTLPWMAPELLNGRSISVSE-K
|. |      ..  .   ..   . ..||.|...||| ||| ||.|..       . |..| ||...         . ||. .||||.|     . .  |
KRGRHGLRFPFPE-HARFYMYQICCALEYCHSHGIIHRDLKPENILLDE------HIKICDFGLARQL------TTFCGTPWYMAPEVL-----GYGKCK

VDVFSFGIVMWELLTGEEPYADLHYGAIIGGIVSNQLRPQVPSSCDPEWQSLMERCWADDPAVRPTFPAIVG-ELRSMMMSLA
.|. |.|....|.|.|. |.   .. ...  |.            .||  .....|.  ||. |||   .   |.  ...   
CDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LZK_b-1.AA HH498 717-980 32 3.7e-58 182.79 In-house 1-284 (284) Show / Hide 
Range on Protein: 717-980
Range on HMM: 1-284/284
Sequence Identity: 32% (95 aa)

LEEIRELGSGTFGTVYHGKWRGTDVAIKRIKASCFFGPPSE-QDRLKDDFWSEACILAHLHHPNVVAFYGVVPDSPGGTLATVTEFMVNGSLKQVL----
.|  .  ||| || || |.||.  ||.|| .|.  |.  |.    . | |  |. |.  | ||.||.| .   | |   .| ||..  ||||  .|    
IEFHEKIGSGSFGKVYKGEWRNKIVAVKRYRAMA-FCCKSDSYQWIVDMFCREVSIMCRLNHPCVVQFVYACCDDP-SQFAIVTQYCDNGSLFSILNTIP

----------HKKE---RILDRRRRLLVAMDAAFGMEYLHD---KKIIHFDLKGENLLVNMRDSQKPVCKVGDLGLS----KIKHKTMVT--GGVRGTLP
          |      ||.|   .. ...| | ||.|||.   . ||| ||   | |.     .    .| | | |     .  ..|    |  |    
IGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIH----EDGHAVVADFGESRFVCDMHDDNMTKQPGNLR----

WMAPELLNGRSISVSEKVDVFSFGIVMWELLTGEEPYADLHYGAIIGGIVSNQLRPQVPSS----CDPEWQSLMERCWADDPAVRPTFPAIVGEL
|||||     .   |.||||||.....||..|.| |....   |    .   . || .| .     .  | .|. .||   |  ||.|  ||  |
WMAPEVFS-QCQKYSIKVDVFSYAMCIWEMHTREVPFHHYKPAAAAAEMAYHHIRPPIPQTPTAQIPHHWSNLIQMCWHPCPENRPDFDQIVTIL
Kinase LZK_b-1.AA Pkinase 717-980 25 4.3e-57 200.78 Pfam 1-293 (293) Show / Hide 
Range on Protein: 717-980
Range on HMM: 1-293/293
Sequence Identity: 25% (76 aa)

LEEIRELGSGTFGTVYHGKWRGTD--VAIKRIKASCFFGPPSEQDRLKDDFWSEACILAHLHHPNVVAFYGVVPDSPGGTLATVTEFMVNG----SLKQV
.. .| .|||.||.||.....||   ||.|.|| .       ...|.     ||..|...|.|||.| .|... |  .. .  |.|.. .|    .|. .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL----SEIQIMKRLNHPNIVRLYDWFED--KDHIYMVMEYCEGGLYVMDLFDY

LH-KKERIL--DRRRRLLVAMDAAFGMEYLHDKKIIHFDLKGENLLVNMRDSQKPVCKVGDLGLSKI--KHKTMVTGGVRGTLPWMAPELLNGRSISVSE
.. .... .  . .    ..   . |.||.|...||| ||| ||.|.. ..  ..  |..| ||.|     .   . .. ||...||||...  .   . 
ISTWRHGCFYFSEWECKFYMYQILRGLEYCHSMGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIR-GGQYYGP

KVDVFSFGIVMWELLTGEEPYADL------HYGAIIGGIVSNQLRPQVPSSCD-------------------PEWQSLMERCWADDPAVRPTFPAIVGE-
|||..|.|....|.|.|. |. .          ..|  | . .|. . | .|.                   .| ......|.. ||. |||.. |.   
KVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQHP

-L
 .
WF
Kinase LZK_b-1.AA Dicty4-Unclassified 717-980 32 1.1e-55 189.15 In-house 1-263 (263) Show / Hide 
Range on Protein: 717-980
Range on HMM: 1-263/263
Sequence Identity: 32% (89 aa)

LEEIRELGSGTFGTVYHGKWRGTDVAIKRIKASCFFGPPSEQDRLKDDFWSEACILAHLHHPNVVAFYG--VVPDSPGGTLATVTEFMVNGSLKQVLH--
.   ...| | |  |. | |.| |||.| .    |    .  . . .||  |  ||  . ||| |  ||  . | |   |.  |.|||  | |  | |  
IQIDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKF----KFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSK

---KKERI-LDRRRRLLVAMDAAFGMEYLHDKKIIHFDLKGENLLVNMRDSQKPVCKVGDLGLSKIKHKTMVTGGVRGTLPWMAPELLNGRSISVSEKVD
   ..  | ||    . .|.| | || .|| . .|| |.|  |.|.          |..|.|.|     .     . ||  | .|| | . |     | |
PSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTRNFIHRDIKSSNILMDKHFN----IKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESY--NQKSD

VFSFGIVMWELLTGEEPYADLH-YGAIIGGIVSNQLRPQVPSSCDPEWQSLMERCWADDPAVRPTFPAIVGEL
|.|......||.||.||| .      .   . .  |||..|..||. |..|   || .||  |||.  |.  |
VYSYAMMLYELATGDEPYQEIQSIMNAARSVCDKKLRPKIPDNCDNFWKKLIKWCWHNDPNKRPTMNQIIQYL
Kinase LZK_b-1.AA DRK 724-982 33 3.5e-53 178.46 In-house 8-258 (258) Show / Hide 
Range on Protein: 724-982
Range on HMM: 8-258/258
Sequence Identity: 33% (88 aa)

GSGTFGTVYHGKWRGTDVAIKRIKASCFFGPPSEQ-DRLKDDFWSEACILAHLHHPNVVAFYGVVPDSPGGTLATVTEFMVNGSLKQVLHKKERILDRRR
| | .| |. | |||| ||.|. ..        .    .  .|  |. ..  | |||.. | |    .|      ..|.|  ||| ..||     .|  .
GRGNYGEVFRGTWRGTQVAVKMLFNHN------INDENFLNEFHREINLMCQLRHPNICQFMGTCNNPP--DICICMEYMPRGSLYNILHDESIEMDWPL

RLLVAMDAAFGMEYLHDKK--IIHFDLKGENLLVNMRDSQKPVCKVGDLGLSK----IKHKTMVTGGVRGTLPWMAPELLNGRSISVSEKVDVFSFGIVM
..  ..|.| || |||     ||| |||  ||||   .. .   || | |||     .| ..     . ||  | ||| |  |.    || ||.||.|| 
MKQMMFDCAKGMIYLHCCNPIIIHRDLKSHNLLVD--EHWQ--VKVADFGLSTRFKKHKQHKFAMTMC-GTPCWTAPEVL--RNQRYTEKADVYSFAIVL

WELLTGEEPYADLHYGAIIGGIVSNQLRPQVPSSCDPEWQSLMERCWADDPAVRPTFPAIVGELRS
||..| . ||.      ..  .    .|| .|  | | .  || .||  ||  ||... ..  | .
WECVTRQDPYFGMPTFQVVFSVGRHGMRPPMPQWCPPKYIQLMNDCWNEDPQHRPSMQECLERLEA
Kinase LZK_b-1.AA LRRK 768-982 31 7.3e-52 178.62 In-house 107-351 (351) Show / Hide 
Range on Protein: 768-982
Range on HMM: 107-351/351
Sequence Identity: 31% (79 aa)

EACILAHLHHPNVVAFYGVVPDSPGGTLATVTEFMVNGSLKQVLHKKER--I------LDRRRRLLVAMDAAFGMEYLHDKK--IIHFDLKGENLLV-NM
|. |. ||.|||.|  .|.  . |   |. |.|.. .|.| ..||.|..  .      ...  .| .|.. | ||||||...  ||| ||| .| |.  .
EVWIMSHLNHPNIVSLKGFCIH-P---LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILLWSS

R-DS------QKPVCKVGDLGLSK--IKHKTMVTGGVRGTLPWMAPELLNGR-SISVSEKVDVFSFGIVMWELLTGE-EPYADLH----Y--GAIIGGIV
  ..      .  ..|..| |.|      .. |. |. |.  ||||| ...   .. .||||..|||...|||||..  |. ..     .    .|  ..
PQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDHMQWMEQIEDKI

SNQLRPQVPSS-CDP-----EWQSLMERCWADDPAVRPTFPAIVGELRS
...||| .|.. | |     . |.|.. ||. ||  ||.|  ||  | .
IEGLRPTIPQHYCPPCQPWHMYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase LZK_b-1.AA LZK 772-980 39 1.7e-49 165.03 In-house 41-241 (241) Show / Hide 
Range on Protein: 772-980
Range on HMM: 41-241/241
Sequence Identity: 39% (83 aa)

LAHLHHPNVVAFYGVVPDSPGGTLATVTEFMVNGSLKQVLHKKERILDRRRRLLV--AMDAAFGMEYLHDKKIIHFDLKGENLLVNMRDSQKPVCKVGDL
| .|.|||...| ||   ||      . |.   | | .|| ..  |.   ..|.|   .. | ||.|||  |||| |||  |.|.   |    | |. | 
LRKLKHPNIIEFKGVCTQSP--CYCIIMEYCPHGQLYEVLRERRTIT---PQLMVDWSKQIAQGMHYLHQHKIIHRDLKSPNILISHND----VVKICDF

GLSKIKHKT-MVTGGVRGTLPWMAPELLNGRSISVSEKVDVFSFGIVMWELLTGEEPYADLHYGAIIGGIVSNQLRPQVPSSCDPEWQSLMERCWADDPA
| |.   .         ||  |||||.   |   .|||||..|||.|.||.||.| ||.|    ||| |. || |.  .||.|      ||  ||   | 
GTSHMWNEMDSTKMSFCGTVAWMAPEVI--RNEPCSEKVDIWSFGVVLWEMLTCEIPYKDVDSMAIIWGVGSNSLHLPMPSTCPEGFKLLMKQCWSQKPR

VRPTFPAIVGEL
 || |  |   .
NRPSFRQILMHW
Kinase LZK_b-1.AA LRRK 717-744 26 8.1e-10 30.9 In-house 1-57 (351) Show / Hide 
Range on Protein: 717-744
Range on HMM: 1-57/351
Sequence Identity: 26% (15 aa)

LEEIRELGSGTFG-TVYHGKWRG----------------------------TDVAIK
|.. ...|.|.|| .|| .||||                            ..||||
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIK
Kinase LZK_b-1.AA LZK 717-747 38 5e-06 16.27 In-house 1-31 (241) Show / Hide 
Range on Protein: 717-747
Range on HMM: 1-31/241
Sequence Identity: 38% (12 aa)

LEEIRELGSGTFGTVYHGKWRGTDVAIKRIK
  |   ||||  | |. |..|.  ||.|...
ISELQWLGSGAQGAVFRGWFRNETVAVKKVR