Gene WAKc-23_a-1 (S.moellendorffii)

WAKc-23_a-1

Species: S.moellendorffii
Alias: WAKc-23_a-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: WAKc23

Sequence

Name Sequence Type Origin Length Description Download
WAKc-23_a-1.AA Protein None 843 None Fasta, JSON
WAKc-23_a-1.NA RNA None 2532 None Fasta, JSON
WAKc-23_a-1.kin_dom Protein Kinase Domain None 193 None Fasta, JSON

Protein domain

Protein domains of WAKc-23_a-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin WAKc-23_a-1.AA B_lectin 116-218 30 2.9e-24 84.94 Pfam 1-137 (137) Show / Hide 
Range on Protein: 116-218
Range on HMM: 1-137/137
Sequence Identity: 30% (42 aa)

LARIIWEANQD---DPV-----SANATLGFEG-DGGLALRDSG-G-RL--VWTT--GPLNGF---STTLELQETGNLTVR-NIDN--E-VLWQS--FGSP
   . | ||.|   .||     . |.|| . . || | | |.| | .   || |  .  ..    ......|..||| .. . .|    |||||  |. |
NQTVVWVANRDLTGNPVTDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDD-NNDSNNVLWQSNTFDHP

TDTLVLQQPLSP------GMR----LESRRSSTNSS--S
|||.   ..|        .|.    | |..|.|| .  |
TDTWLPGMKLGWDNNVTIYMNWIGYLTSWKSNTN-YDPS
B_lectin WAKc-23_a-1.AA B_lectin 77-191 23 8.5e-10 39.79 SMART 1-126 (126) Show / Hide 
Range on Protein: 77-191
Range on HMM: 1-126/126
Sequence Identity: 23% (30 aa)

GYTAPNLSLLNVAQY--S--LAFVNHSSGLFTLAIVTNSSAGSLARIIWEA--NQDDPVSA---NATLGFEGDGGLALRDSGGRLVWTTGPL-NGFSTTL
 .|  .   |   .   .  | |... .  ... |. ... ..  ...| |  | | ||.    ...| .  || | . |  .| || ..   |   ...
DNTLSSGQTLVSGNSLFEFYLGFFTFIMQ-WCNGIWYKNISNKQRTVVWVAQPNRDNPVHDGNNSCYLTMQSDGNLVIYD--NRPVWSSNTTRNNGNYVA

ELQETGNLTVRNID----NEVLWQSFGSP
.||..||. ... |    ....|||| .|
VLQDDGNFVIYDPDDNDSGNFIWQSFDHP
PAN_AP WAKc-23_a-1.AA PAN_AP 381-455 21 0.000245 21.12 SMART 1-85 (85) Show / Hide 
Range on Protein: 381-455
Range on HMM: 1-85/85
Sequence Identity: 21% (19 aa)

SSSLDFVSLPGIEHFSHRY----LNGSSLSFQLCRSQCLQNCSCSAFFFWEESSSCFLMD---SLRTLQ------AVPNHRHVAYVKV
.. ..|| .|...  . .     .   . | . |...||.|||| .| . . ...| |..   .|   .       .|| . . | |.
CCDDCFVRMPNMKL-FSPIVNWVDVI-VMSLEECMQKCLNNCSCRSFMYYN-TKGCHLWSWDSHLGDPRQFKRFMKFPNQGVDYYEKN
Kinase WAKc-23_a-1.AA TKL 547-803 19 7.4e-47 161.99 In-house 1-364 (364) Show / Hide 
Range on Protein: 547-803
Range on HMM: 1-364/364
Sequence Identity: 19% (73 aa)

IGTGSFGSVYEGVLPE---------GRKVAVKRLES---TGQGK-------------------------RKIFAEVAVLGTFHHWNLVRLLGFCDQGCHG
|| |.|| || |..           |. ||||.. |       |                          ..  |. ..  ..| |.|...|.| .. .|
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-------------FIIYEHIGNGSLDRWIYRDNGENVLDWELRMGIVMGIARGLAYLHE-------ECMEVHLNLKPQNVLLDSSFV-------------
             .|..| . .|||   .          |..|. ....||||..|||         .  .| .||..|.|.|. .              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-PKLSGYGVSRIMARESQSSAA-------------------KTGLESYHPPEWLLDT----------------SITEKCDVYSFGILLLEIISGKRSSNS
 .|.. .| || | .......                    . |   . .|| | ..                . .||||||||||.| ||....|    
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR----

DKFYLPAHALD-LTRQGRQMELVDTRIVKDSSES---------------KVRQGV-----SIAFQCLQEDPRSRPSMGDVVQML
     | . ..  .....    ..  ........                    .     ... .| ..||..|||. .... |
-----PYYDYPYMPMIFQD-P-FEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase WAKc-23_a-1.AA TKL-Unique 543-736 25 1.6e-36 126.34 In-house 1-226 (290) Show / Hide 
Range on Protein: 543-736
Range on HMM: 1-226/290
Sequence Identity: 25% (59 aa)

FSKLIGTGSFGSVYEGVLPEGRKVAVKRLE-STGQGKRKIF---AEVAVLGTFH-HWNLVRLLGFCD----QGCHGFIIYEHIGNGSLDRWIYR------
|...||.|..|.|| |. . | .||.|...   .. .....    || .. ..| | |.|.. |.|     .  . .|. | .  |||.  . .      
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

-DNGENVLDWELRMGIVMGIARGLAYLHEECM-EVHLNLKPQNVLLDSS-----FVPKLSGYGVSRIMARESQSSAA------KTGLE---SYHPPEWLL
  | .. |....|. ..  ||.|. ||| .     |..||..|.|.|.      .  |... | |.. ........       ... .    . .|| | 
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

D--TSITEKCDVYSFGILLLEIISGKR
.  . ..||.||||||| | ||...|.
MNFCQYSEKSDVYSFGIVLWEIATRKI
Kinase WAKc-23_a-1.AA IRAK 542-736 31 4.3e-29 100.32 In-house 2-222 (317) Show / Hide 
Range on Protein: 542-736
Range on HMM: 2-222/317
Sequence Identity: 31% (70 aa)

NFSKLIGTGSFGSVYEGVLPEGRK--VAVKRLE-----STGQGKRKIFA---EVAVLGTFHHWNLVRLLGFCDQGCHGFIIYEHIGNGSL-DRWIYRDNG
. . .|| | || || |..  .    .|||.|      |... ..   .   |. |. ...| |.| |.|.| ..     .|. . |||| ||   .|. 
HKDNRIGEGGFGCVYRGQW-KNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

ENV--LDWELRMGIVMGIARGLAYLHEEC---MEVHLNLKPQNVLLDSSFVPKLSGYGVSRIM----ARESQSS-AAKTGLES----YHPPEWLL--DTS
     | |  |  |  |.|.|. .||.        | . |. |.|||  |.||..  |  |      ..|.|..  ..| .      | ||| .      
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

ITEKCDVYSFGILLLEIISGKR
.| | ||||||| |||...| |
LTKKTDVYSFGIVLLEVLTGCR
Kinase WAKc-23_a-1.AA Pkinase 542-803 20 1.9e-28 101.67 Pfam 2-293 (293) Show / Hide 
Range on Protein: 542-803
Range on HMM: 2-293/293
Sequence Identity: 20% (63 aa)

NFSKLIGTGSFGSVYEGVLPEGRK-VAVKRLESTGQGKRK---IFA--EVAVLGTFHHWNLVRLLGFCDQGCHGFIIYEHIGNG----SLDRWIY-RDNG
 . . || ||||.||...    .| ||||...  .. . |    .   |....  ..| | |||....  . |  .. |. ..|    .| ..|  ...|
HIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHG

ENVLDWELRMGIVMGIARGLAYLHEECMEVHLNLKPQNVLLDSSFVP----KLSGYGVSRIM-ARESQSSAAKTGLESYHPPEWLL-DTSITEKCDVYSF
   ....    ..  |.|||.|.|. .  .|  |||.|.|.|.  ..    |..  |... .    ..     .|   | .||... .. .. |.|..|.
CFYFSEWECKFYMYQILRGLEYCHS-MGIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDMWSC

GILLLEIISGKRSSNSDKFYLPAHALDLTRQGRQMELVDTRIVKDSSESKV-----------------------RQGVSIAFQCLQEDPRSRPSMGDVVQ
|..| | ..|.       .  | |  .  .  .||.... .  .. ...                         . . ..   ||. || .||.  ...|
GCILYEMLCGR-------PPFPGHC-WHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKRPTAEQILQ

M--L
   .
HPWF
Kinase WAKc-23_a-1.AA TK 541-733 16 6.2e-27 86.69 In-house 1-389 (486) Show / Hide 
Range on Protein: 541-733
Range on HMM: 1-389/486
Sequence Identity: 16% (66 aa)

DNFSKLIGTGSFG---SVYEGVLPEGR--------------------------KVAVKRLEST-GQGKRKIFA--------------EVAVLGTFH----
  . | .| | ||    ||.| . ...                          .|||| | .. .. ..  |.              |....  ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HWNLVRLLGFCDQGC------------HGFIIYEHIGNGS----LDRWIY--RDNGEN-----------------------------------------
 | |.|||.| | ||             .  |. |.  .|.    |. .    |... .                                         
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------VLDWELRMGIVMGIARGLAYLHEE-C----MEVHLNLKPQNVLLDSSFV-----------PKLSGYGVSR
                               |. . .. . . ||.|..|||.  |      || .|   |.|.... |            |.. .| ||
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

I----MARESQSSAAKTGLESY------------------------------HPPEWLLDTS---------ITEKCDVYSFGILLLEIIS
     .||. .|.   .  .||                               .|| |.|            |.| ||.|||.|. || .
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase WAKc-23_a-1.AA LRRK 542-736 20 3.9e-24 82.27 In-house 2-281 (351) Show / Hide 
Range on Protein: 542-736
Range on HMM: 2-281/351
Sequence Identity: 20% (59 aa)

NFSKLIGTGSFG-SVYEGVLPE---------------------------GRKVAVKRLEST-------------------------------GQGKRKIF
 . ..|| |.|| .|| . .                             . .||.| .. .                               .... ..|
KIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRAF

A----EVAVLGTFHHWNLVRLLGFCDQGCHGFIIYEHIGNGSLDRWIYRDNGEN------VLDWELRMGIVMGIARGLAYLHEEC-MEVHLNLKPQNVLL
     ||... ...| |.| |.||| .  .  .. | . .|.|.. .             ...| |.  |.. ||.|..|||    . .| .||. |.||
REFRHEVWIMSHLNHPNIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSHNPPIIHRDLKSPNILL

DSS------------FVPKLSGYGVSRIMARESQSSA-AKTGL--ESYHPPEWLLDT---SITEKCDVYSFGILLLEIISGK-R
 ||             . |.. .| || |   .  .. ||. .  . .. || . ..   . ||| |.||||..| |..... .
WSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHH
Kinase WAKc-23_a-1.AA S_TKc 541-803 21 2.4e-22 81.47 SMART 1-231 (231) Show / Hide 
Range on Protein: 541-803
Range on HMM: 1-231/231
Sequence Identity: 21% (61 aa)

DNFSKLIGTGSFGSVYEGVLPE-GRKVAVKRLESTGQGKRKIFAEVAVLGTFHHWNLVRLLGFCDQGCHGFIIYEHIGN--GSLDRWIYRDNGENV---L
  . ..|| |.||.|| ..  . ||.||.|..       ..|  |...|   || |.|.|.....   | ... |....  |.| . | . ...     .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPF

DWELRMGIVMGIARGLAYLHEECMEVHLNLKPQNVLLDSSFVPKLSGYGVSRIMARESQSSAAKTGLESYHPPEWLLDTSITE-KCDVYSFGILLLEIIS
.      ..  |...|.|.|.    .|  |||.|.|||.  . |..  |..|..           |   | .|| |   . .  |||..|.|..| | ..
PE-HARFYMYQICCALEYCHSH-GIIHRDLKPENILLDE--HIKICDFGLARQL-------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYEMLC

GKRSSNSDKFYLPAHALDLTRQGRQMELVDTRIVKDSSESKVRQGVSIAFQCLQEDPRSRPSMGDVVQ---------ML
|.          ..  ... .                     ... ..  .||| ||. ||.  .. |          .
GYPPFP-----QMQMMFKKIG--------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase WAKc-23_a-1.AA Src-Echino1 542-735 30 2.5e-22 73.9 In-house 2-195 (252) Show / Hide 
Range on Protein: 542-735
Range on HMM: 2-195/252
Sequence Identity: 30% (61 aa)

NFSKLIGTGSFGSVYEGVLPEGRKVAVKRLESTGQGKRKIFAEVAVLGTFHHWNLVRLLGFCDQGCHGFIIYEHIGNGSLDRWIYRDNGENVLDWELRMG
 . | || | .| |..||     .|||| |      . .  ||  |. .  | ..|..   |      .|. | . ||.|  .. |... .|    .   
RMDKKIGKGHCGEVWKGVWNGNTPVAVKTLKEKTMSPADFLAEANVMKKCRHEGIVQIYAVCSDKEPIYIVTELMSNGNLQDYLKRGKCKHV---KMTTL

IVMG--IARGLAYLHEECMEVHLNLKPQNVLLDSSFVPKLSGYGVSRIMARES--QSSAAKTGLESYHPPEWLLDTSITEKCDVYSFGILLLEIIS-GK
| ||  || |. || .  . || .|  .|||..   | |.  .|  |.| ..       ||  .  .  ||  |  . | | ||.|||||. |..  |.
IDMGAHIASGMDYLGSKNV-VHRDLAARNVLVGKGNVCKIADFGLARMMQKDVYCGKQGAKLPIK-WTAPEAALYGRFTIKSDVWSFGILMTEMVTFGR
Kinase WAKc-23_a-1.AA Frk 542-732 27 5.3e-22 72.75 In-house 2-196 (260) Show / Hide 
Range on Protein: 542-732
Range on HMM: 2-196/260
Sequence Identity: 27% (55 aa)

NFSKLIGTGSFGSVYEGVLPEGRKVAVKRLESTGQGKRKIFAEVAVLGTFHHWNLVRLLGFCDQGCHGFIIYEHIGNGSLDRWIY--RDNGENVLDWELR
 . . .|.| || |.||       ||||.| .     .   .|  ..    |  |..|   |      .|| | . .|||  ..    |.|.. .  .  
QLIRRLGSGQFGEVWEGLWNNTTPVAVKTLKPGTMDPNDFLREAQIMKKLRHPKLIQLYAVCTVEEPIYIITELMRHGSLQEYLQAINDKGRQ-CQMQQL

MGIVMGIARGLAYLHEECMEVHLNLKPQNVLLDSSFVPKLSGYGVSRIMARESQ-SSAAKTGLE---SYHPPEWLLDTSITEKCDVYSFGILLLEII
. .   .| |.||| |.   .|  |   |||.. . . |.  .|. |.. .. .    ...|      .  ||     . | | ||.|||||| |||
VDMAAQVAAGMAYL-ESQNYIHRDLAARNVLVGEHNICKIADFGLARVLMKDNEDIYESRHGARFPIKWTAPEAANYNKFTIKSDVWSFGILLTEII
Kinase WAKc-23_a-1.AA TK-Unique 542-733 24 1.2e-21 71.51 In-house 2-234 (294) Show / Hide 
Range on Protein: 542-733
Range on HMM: 2-234/294
Sequence Identity: 24% (57 aa)

NFSKLIGTGSFGSVYEGVLPE-------GRKVAVKRLE--STGQGKRKIFAEVAVLGTFH-HWNLVRLLGFCDQGC-HGFIIYEHIGNGSLDRWIY--RD
.. ..||.|.|| |. | . .        ..|||| |.  .|.. |.. . | ...     | |.|..|| |       .||.|.. .|.|.  .   |.
EVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCRP

N-----------------GENVLDWELR----MGIVMGIARGLAYLHE-ECMEVHLNLKPQNVLLDSSFVPKLSGYGVSR-IMARESQSSAAK--TGLES
.                  . ... ..       .  .||.|..||..  .. || .|   |||| . .| |....| .| ..... .|.  .  .    
AMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGRIPIR

YHPPEWLL--DTSI-TEKCDVYSFGILLLEIIS
. .|| |.  .  . |.| ||.|||.|. || .
WMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase WAKc-23_a-1.AA STE 543-735 19 1.3e-21 73.11 In-house 1-265 (359) Show / Hide 
Range on Protein: 543-735
Range on HMM: 1-265/359
Sequence Identity: 19% (54 aa)

FSK--LIGTGSFGSVYEGVLPE----------------GRKVAVKRLESTGQG------------------KRKIFAEVAVLGTFH--HWNLVRLLGFCD
. .   || |.||.|| ..  .                |. .|.|...   .                   . .|  |. ..  ..  | | |. .| . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

QGC-------HGFIIYEHIGNGSLDRWIY---RDNG-------------ENVLDWELRMGIVMGIARG-LAYLHEECMEVHLNLKPQNVLLDSSFVPKLS
...       . .|. |....||||  |      ..             |... .     |.  | .| |.|||.    .|  .||.|.||      ||.
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAY-----ICRQILKGLLYYLHSHH-IIHRDIKPANILL-----VKLC

GYGVSRIMARE----------------SQSSAAKTGLESYHPPEWLL------DTSITEKCDVYSFGILLLEIISGK
  ||. ... .                .| .   .|   .  || ..      |   ..|||..|.|....| . ||
DFGVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase WAKc-23_a-1.AA Pkinase_Tyr 542-655 27 9.3e-21 70.92 Pfam 2-129 (270) Show / Hide 
Range on Protein: 542-655
Range on HMM: 2-129/270
Sequence Identity: 27% (35 aa)

NFSKLIGTGSFGSVYEGVLP-----EGRKVAVKRL--ESTGQG--KRKIFAEVAVLGTF-HHWNLVRLLGFCD-QGCH--GFIIYEHIGNGSLDRWIYRD
 | | .| |.||.||.|..      .. .|||| |   .. .   ... ..|.... .. || |.|||.| |  || .   .|. |.  .|.|.    . 
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKH

-NGENVLDWELRMGIVMGIARGLAYLHE
 .... |. .   .. . ||.|..||..
REDKQPLTMKDLLQMCWQIAKGMEYLES
Kinase WAKc-23_a-1.AA MLK 542-672 27 3.4e-19 63.34 In-house 2-161 (291) Show / Hide 
Range on Protein: 542-672
Range on HMM: 2-161/291
Sequence Identity: 27% (44 aa)

NFSKLIGTGSFGSVYEGVLPEGRK-----VAVKRLE-------STGQGKRKIFAEVAVLGTFHHWN----LVRLLGFCDQ-GCHGFIIYEHIGNGSLDRW
.|.. || ||||.|. |.   ..      ||||| .       .|.  ....  |.  |  . | |     ....| | | .|| .|. | . .||| . 
QFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

IYRD--------NGEN---VLDWELRMGIVMGIARGLAYLHEECME--VHLNLKPQNVLLD
..          ....   | | .. | . . .|||..|||..     .|  ||..|.|.|
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILID
Kinase WAKc-23_a-1.AA TyrKc 541-803 23 1.2e-17 62.52 SMART 1-280 (280) Show / Hide 
Range on Protein: 541-803
Range on HMM: 1-280/280
Sequence Identity: 23% (70 aa)

DNFSKLIGTGSFGSVYEGVLPEGRKVAVKRLESTGQGKRKIFAEVAVLGTF--HHWNLVRLLGFCDQG-------CHGFIIYEHIGNGSLDRWI--YRDN
  . | .| | || ||.|..   ..|||| | .    .. .  |  ..  .  || |.|||.| | |.          .|. |.  .|.|.  .  .|..
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

GENVLDWELRMGIVMGIARGLAYLHEECMEVHLNLKPQNVLLDSSFVPKLSGYGVSRIMARE------SQSSAAKT--GLES-----YHPPEWLLDTSIT
    | ..    .   ||.| .|||. .  .|  |   |.|... .. | |  | ||    .      ..   .|.  |  .       .|| . .   |
----LCMKDLLSFCWQIACGMEYLHSKNC-IHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

EKCDVYSFGILLLEIISGKRSSNSD---KFYLPAHALDLTRQGRQMELVDT-----RIVKDSSESKVRQGVSIAFQCLQEDPRSRPSMGDVVQML
.| ||.|||... || .   .  ..   ..  ..... . .||. |.  .        |  ..|       .|  || .||| .||.. .... .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSF-VCCPDEM-----YQIMKQCWHEDPEDRPTFSEIHECF
Kinase WAKc-23_a-1.AA MLK 716-735 45 4e-06 17.36 In-house 214-233 (291) Show / Hide 
Range on Protein: 716-735
Range on HMM: 214-233/291
Sequence Identity: 45% (9 aa)

TEKCDVYSFGILLLEIISGK
.|||||.|.|..| |.....
SEKCDVWSWGVVLWEMLTRE
Kinase WAKc-23_a-1.AA TK 784-803 35 8e-06 14.75 In-house 467-486 (486) Show / Hide 
Range on Protein: 784-803
Range on HMM: 467-486/486
Sequence Identity: 35% (7 aa)

QCLQEDPRSRPSMGDVVQML
|| ..||. ||.. .....|
QCWHYDPEDRPTFSQLHEQL
Kinase WAKc-23_a-1.AA MLK 784-803 50 9e-06 16.13 In-house 272-291 (291) Show / Hide 
Range on Protein: 784-803
Range on HMM: 272-291/291
Sequence Identity: 50% (10 aa)

QCLQEDPRSRPSMGDVVQML
|| ..||..|||.  .|| |
QCWNQDPHKRPSFRQIVQHL
Kinase WAKc-23_a-1.AA TK-Unique 784-803 35 0.000207 11.26 In-house 275-294 (294) Show / Hide 
Range on Protein: 784-803
Range on HMM: 275-294/294
Sequence Identity: 35% (7 aa)

QCLQEDPRSRPSMGDVVQML
.|.|..| .|||  .....|
SCWQWEPEERPSFRQIKHRL
Kinase WAKc-23_a-1.AA LRRK 784-805 36 0.000215 11.44 In-house 330-351 (351) Show / Hide 
Range on Protein: 784-805
Range on HMM: 330-351/351
Sequence Identity: 36% (8 aa)

QCLQEDPRSRPSMGDVVQMLQG
.| |.||..||.. ..|. |  
HCWQHDPKKRPHFSQIVKRLSQ
Kinase WAKc-23_a-1.AA Pkinase_Tyr 706-733 42 0.001081 13.13 Pfam 182-209 (270) Show / Hide 
Range on Protein: 706-733
Range on HMM: 182-209/270
Sequence Identity: 42% (12 aa)

PPEWLLDTSITEKCDVYSFGILLLEIIS
.|| . .   |.| ||.|||.|. ||..
APECINYGKFTTKSDVWSFGVLMWEIFT
Kinase WAKc-23_a-1.AA Pkinase_Tyr 784-803 35 0.001518 12.63 Pfam 251-270 (270) Show / Hide 
Range on Protein: 784-803
Range on HMM: 251-270/270
Sequence Identity: 35% (7 aa)

QCLQEDPRSRPSMGDVVQML
|| ..||  ||.. .....|
QCWHYDPEDRPTFSEIHEQL
Kinase WAKc-23_a-1.AA TKL-Unique 784-803 40 0.060346 2.87 In-house 271-290 (290) Show / Hide 
Range on Protein: 784-803
Range on HMM: 271-290/290
Sequence Identity: 40% (8 aa)

QCLQEDPRSRPSMGDVVQML
||   ||  |||  ...  |
QCWHHDPSQRPSFDEIIHRL
Kinase WAKc-23_a-1.AA IRAK 780-803 29 0.316901 0.3 In-house 294-317 (317) Show / Hide 
Range on Protein: 780-803
Range on HMM: 294-317/317
Sequence Identity: 29% (7 aa)

SIAFQCLQEDPRSRPSMGDVVQML
. | .|. .  . |..|  |.| |
QCACCCGHHRANRRCDMAWVMQQL