Gene SD2b2_e (S.moellendorffii)

SD2b2_e

Species: S.moellendorffii
Alias: SD2b2_e
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: SD2b2

Sequence

Name Sequence Type Origin Length Description Download
SD2b2_e.AA Protein None 451 None Fasta, JSON
SD2b2_e.NA RNA None 1356 None Fasta, JSON
SD2b2_e.kin_dom Protein Kinase Domain None 196 None Fasta, JSON

Protein domain

Protein domains of SD2b2_e.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase SD2b2_e.AA TKL 78-338 21 4.7e-63 215.8 In-house 1-364 (364) Show / Hide 
Range on Protein: 78-338
Range on HMM: 1-364/364
Sequence Identity: 21% (83 aa)

LGSGGFGEVFKGSIQG----------EAVAVKRLMRFDD------------------------------KQFRAEVSTIGTIQHMNLVRLRGFCADGAL-
.||||||||.||  .|          . ||||.. . .|                              .... |.  .  ..| |.|.. |.| ..   
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

-----------QRLLVYEFVERGSLDRSLFNRDAENSIVLSWTQRFGIALGTAKGLAYLHE----ECRDR--IIHCDIKPENILLDAEMK----------
           |  .|.|....|||   |            | ||. .||..|.|..|||      |.    |||.|.|..|||.|  ..          
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPN

----PKVGDFGLAKLMGREFS------------------RVVTSMRGTRGYLAPEWLSNM----------------PITPKADVYSYGMTLLEIISGRRN
    .|..||||.. | ....                      . .|| ...||| | ..                . ..|.||||.|. | ||....| 
ADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-

VNVQSKQPFYPFWAAQQV---------RNGEFAKLPDDRLEEWD--------EDELRRAAKTALWCVQDDEINRPSMKTVVQML
       |.| ..  ...               .|.  . ..|         .| ... .| . .| . |  .|||...... |
-------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase SD2b2_e.AA IRAK 74-272 35 5.4e-49 169.08 In-house 1-224 (317) Show / Hide 
Range on Protein: 74-272
Range on HMM: 1-224/317
Sequence Identity: 35% (79 aa)

FRKQ--LGSGGFGEVFKGSIQGEA--VAVKRLMRFDD-------KQFRA---EVSTIGTIQHMNLVRLRGFCADGALQRLLVYEFVERGSLDRSLFNRDA
| |   .|.||||.|..| .....  .|||.|.   |       ..|..   |. .  ...| |.| | |.|...  .  |||..   |||   |  .|.
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQ-CHCLVYPYMPNGSLEDRLWCQDG

ENSI-VLSWTQRFGIALGTAKGLAYLHEEC-RDRIIHCDIKPENILLDAEMKPKVGDFGLAKLM----GREFSRV----VTSMRGTRGYLAPEWLS--NM
 ..   ||| ||. |..|||.|. .||.      ||| |||. |||||. . || .||||.       ..| . .    .   |||  |..|| .     
QCPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

PITPKADVYSYGMTLLEIISGRRNV
 .|.| |||| |  |||...|.| |
QLTKKTDVYSFGIVLLEVLTGCRAV
Kinase SD2b2_e.AA Pkinase 76-338 23 9.6e-44 155.76 Pfam 5-293 (293) Show / Hide 
Range on Protein: 76-338
Range on HMM: 5-293/293
Sequence Identity: 23% (75 aa)

KQLGSGGFGEVFKGSIQGEA--VAVKRLMRFDDKQFRA-------EVSTIGTIQHMNLVRLRGFCADGALQRLLVYEFVERG----SLD----RSLFNRD
...|||.||.|.|.  .|.   ||||.. . ..|           |..    ..| | |||.... |      .| |..| |    .|     .      
RKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFED-KDHIYMVMEYCEGGLYVMDLFDYIST------

AENSIVL--SWTQRFGIALGTAKGLAYLHEECRDRIIHCDIKPENILLDAEMKP----KVGDFGLAKLMGREFSRVVTSMRGTRGYLAPEWLS-NMPITP
 ... ..  |. .   ... ...||.|.|..   .|||.|.||||||.| .. .    |..||||||..    ..  |.  ||..|.|||..  . ...|
-WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGP

KADVYSYGMTLLEIISGRRNVNVQSKQPFYPFWAA-------QQVRNGEFAKLPDDRLEEWDEDEL-----------------RRAAKTALWCVQDDEIN
|.|..|.| .| | ..||            ||. .       |...  .  . | .. ..|. ..                  . . .   || . |   
KVDMWSCGCILYEMLCGR-----------PPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKK

RPSMKTVVQM--L
||. . ..|   .
RPTAEQILQHPWF
Kinase SD2b2_e.AA TKL-Unique 74-268 29 8.3e-41 141.65 In-house 1-224 (290) Show / Hide 
Range on Protein: 74-268
Range on HMM: 1-224/290
Sequence Identity: 29% (67 aa)

FRKQLGSGGFGEVFKGSIQGEAVAVKRLM-----RFDDKQ-FRAEVSTIGTIQ-HMNLVRLRGFCAD---GALQRLLVYEFVERGSLDRSLF-----NRD
| . .|.||.|.|.||   |. ||.|..      ... .| |. ||... ... | |.|.. |.|.|    . .. .| |....|||.  |      |  
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNN

AENSIVLSWTQRFGIALGTAKGLAYLHEECRDRIIHCDIKPENILLDAE-----MKPKVGDFGLAKLMGREFSRVVT--------SMRGTRGYLAPEWLS
 .|.. |.. ||  .|.  |.|. ||| .    |||.|.|. |.|.| .     .. |. ||||.|.  ..    ..        .  |.  ..||| |.
NNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

N--MPITPKADVYSYGMTLLEIISG
.    .. |.||||.|. | ||...
MNFCQYSEKSDVYSFGIVLWEIATR
Kinase SD2b2_e.AA MLK 74-269 27 2.3e-38 130.72 In-house 3-233 (291) Show / Hide 
Range on Protein: 74-269
Range on HMM: 3-233/291
Sequence Identity: 27% (64 aa)

FRKQLGSGGFGEVFKGSIQGEA-----VAVKRLM-RF----D----DKQFRAEVSTIGTIQHMN----LVRLRGFCADGALQRLLVYEFVERGSLDRSLF
| . .|||.||.|.||  ...      |||||   |.    |    ...|. |.     ..| |     ....| |..   . ..| |..| ||| . | 
FHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVLH

NRDAENS---------IVLSWTQRFGIALGTAKGLAYLHEECRDRIIHCDIKPENILLDA------EMKPKVGDFGLAKLMGREFSRV---VTSMRGTRG
... . .         .| .  . . .||  |.|..|||.. .. ||| |.|. |||.|.      ... |. |||..    |....     .|..||  
GARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTS----RDWHQMCTNMMSNAGTYA

YLAPEWL---SNMPITPKADVYSYGMTLLEIISGR
. ||| .    . . . |.||.|.|. | |.....
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase SD2b2_e.AA Dicty4 74-265 33 6.8e-36 117.31 In-house 3-210 (277) Show / Hide 
Range on Protein: 74-265
Range on HMM: 3-210/277
Sequence Identity: 33% (70 aa)

FRKQLGSGGFGEVFKGSIQGEAVAVKRL--MRFDD-----KQFRAEVSTIGTIQHMNLVRLRGFCA-----DGALQRLLVYEFVERGSLDRSLFN--RDA
. . .|.|.||||.||.  | .|||| |     ..     . ||.||.  . |.| |.. . | |       | ..   | |.. .|.| . | .   . 
IEQRIGKGSFGEVYKGTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMC--IVTEYMPKGNLYSLLHDKPSEQ

ENSIVLSWTQRFG---IALGTAKGLAYLHEECRD-RIIHCDIKPENILLDAEMKPKVGDFGLAKLMGREFSRVV--TSMRGTRGYLAPEWLSNMPITPKA
  || |.|. .     .|. .|.|...||  |.. .||| |.|. |.| |. .. ||.||||...| .. .     ... || .. ||| . . | . ||
QQSIKLDWPLIKRAMRMAFDAARGMNWLH--CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSYGMTLLEI
||||.|. | ||
DVYSFGIVLWEI
Kinase SD2b2_e.AA TK 74-267 16 6.9e-34 110.42 In-house 3-389 (486) Show / Hide 
Range on Protein: 74-267
Range on HMM: 3-389/486
Sequence Identity: 16% (63 aa)

FRKQLGSGGFG---EVFKGSIQG---------------------------EAVAVKRLM---RFDDKQFRA--------------EVSTIGTIQ-----H
. |.||.| ||   ||.||  .|                           . |||| |.     ....|..              |.. .   .     |
LGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHH

MNLVRLRGFCADGA-----------LQRLLVYEFVERGS----LDRSLFNRDAENSI-------------------------------------------
 |.||| | | .|.              ..| |... |.    |.  | ... . .                                            
PNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDD

----------------------------VLSWTQRFGIALGTAKGLAYLHEE----CRDRIIHCDIKPENILLDAEMK-----------PKVGDFG----
                             |.  |.  ...  |.|..|||.        ...| |.   |.|.. ...            |..|||    
DLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LAKLMGREFSRVVTSMRGTRG-------------------------YLAPEWLS---------NMPITPKADVYSYGMTLLEIIS
    ||. ....   ...| .||..                         ..||| |          .   |.| ||.|.| .. || .
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase SD2b2_e.AA Dicty4-Unclassified 74-268 32 8.2e-32 106.2 In-house 3-204 (263) Show / Hide 
Range on Protein: 74-268
Range on HMM: 3-204/263
Sequence Identity: 32% (68 aa)

FRKQLGSGGFGEVFKGSIQGEAVAVKRLMRFDDK-------QFRAEVSTIGTIQHMNLVRLRGFCADG---ALQRLLVYEFVERGSLDRSLFN---RDAE
  . .| | | .| ||   |  |||| .    .|        |..||   | ||| |||...| |            | ||  .| |   . .    . .
IDQFIGKGHFSKVHKGNWKGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNL-FEVIHSKPSEQQ

NSIVLSWTQRFGIALGTAKGLAYLHEECRDRIIHCDIKPENILLDAEMKPKVGDFGLAKLMGREFSRVVTSMRGTRGYLAPEWLSNMPITPKADVYSYGM
 .| |  |    .|.  |.|...||   |. .|| |||  |||.|     |..|||..     .|    |   ||    .|| |     . |.|||||.|
QPIKLDDTLIIKYAFDIAQGMQHLH--TRN-FIHRDIKSSNILMDKHFNIKIADFGISRVI--DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAM

TLLEIISG
 | | . |
MLYELATG
Kinase SD2b2_e.AA LRRK 73-270 24 1.9e-30 104.93 In-house 2-281 (351) Show / Hide 
Range on Protein: 73-270
Range on HMM: 2-281/351
Sequence Identity: 24% (71 aa)

GFRKQLGSGGFG-EVFKGSIQG----------------------------EAVAVKRLMRF-----------DD--------------------------
 . .|.|.|||| .|...  .|                            . ||.| . |            ..                          
KIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRAF

KQFRAEVSTIGTIQHMNLVRLRGFCADGALQRLLVYEFVERGSLDRSLFNRDAENS-----IVLSWTQRFGIALGTAKGLAYLHEECRDR--IIHCDIKP
  || ||. . . .| |.| | ||| .    . .| |..  |.|.. |.|. ....     ...||. .  |||  |||..|||   . .  |||.| |.
REFRHEVWIMSHLNHPNIVSLKGFCIHP---LCMVMEYAPHGDLYHFLHNK-KQDGFHFMKAHISWMLKLKIALQIAKGMEYLH---SHNPPIIHRDLKS

ENILL---D---------AEMKPKVGDFGLAKLMGREFSR-VVTSMRGTRGYLAPEWLSNM---PITPKADVYSYGMTLLEIISGR-R
.||||   .         |... |..|||.   |   |   |.  . |. |..||| . ..     | |.|.||.|| | |..... .
PNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHH
Kinase SD2b2_e.AA LISK 77-270 28 2.1e-28 89.24 In-house 1-237 (296) Show / Hide 
Range on Protein: 77-270
Range on HMM: 1-237/296
Sequence Identity: 28% (69 aa)

QLGSGGFGEVFKGSIQ--GEAVAVKRLMR----FDDKQFRA----EVSTIGTIQHMNLVRLRGFCADGALQRLLVYEFVERGSLDRSLFNRDAENSIVLS
 .|.|.||.|.||.    |. .|.| . |    ..|. ..     || ..  ..| | |.  | |     |  .| |... | | . |...|   .|.|.
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDK-HKIPLP

WTQRFGIALGTAKGLAYLHEECRDRIIHCDIKPENILLDAE----MKPKVGDFGLAKLMGREF--------------------------------SRV-V
|.||  |||. |.|..|||. .   ||| | |  |.|..       . ||.|||.|..|  |                                 .|   
WPQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRR

TSMRGTRGYLAPEWLSNMPITPKADVYSYGMTLLEIISGRR
 .. ||    ||| |  .  . ..||.|.|. |.||| ...
MTICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVK
S_TKc SD2b2_e.AA S_TKc 72-338 22 2.4e-26 94.76 SMART 1-231 (231) Show / Hide 
Range on Protein: 72-338
Range on HMM: 1-231/231
Sequence Identity: 22% (65 aa)

DGFRKQLGSGGFGEVFKGSIQG--EAVAVKRLMRFDDKQFRAEVSTIGTIQHMNLVRLRGFCADGALQRLLVYEFVER--GSLDRSLFNRDAENS---IV
  . ...|.|.||.|.|.   .  . ||.|..     ...| |..     .| |.|.| ... |      .| |...   |.| . . .|  .     . 
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK----EHIRREIQILKK-HHPNIVKLYDVFQD--DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

LSWTQRFGIALGTAKGLAYLHEECRDRIIHCDIKPENILLDAEMKPKVGDFGLAKLMGREFSRVVTSMRGTRGYLAPEWLSNMPITP-KADVYSYGMTLL
  ....  ..  ....|.|.|.     |||.|.||||||||     |..|||||...        |.. ||. |.||| |   . .. |.|..| | .| 
E-HARF--YMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

EIISGRR---NVNVQSKQPFYPFWAAQQVRNGEFAKLPDDRLEEWDEDELRRAAKTALWCVQDDEINRPSMKTVVQ---------ML
| ..|.    ....  |.                                . |      | | |  .||.   . |          .
EMLCGYPPFPQMQMMFKKIG-----------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase SD2b2_e.AA RIPK 78-269 28 3.2e-26 86.35 In-house 1-225 (290) Show / Hide 
Range on Protein: 78-269
Range on HMM: 1-225/290
Sequence Identity: 28% (65 aa)

LGSGGFGEVFKGS--IQGEAVAVKR---------LMRFDDKQFRAEVSTIGTIQHMNLVRLRGFCADG--ALQRL---LVYEFVERGSLDRSLFNRDAEN
.|.||||||||     .|. ||.|          . . . ..   |.     ... . |.. ||| .   . .     .| |. | |||   |  .    
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

SIVLSWTQRFGIALGTAKGLAYLHEECRD-RIIHCDIKPENILLDAEMKPKVGDFGLAKLMGRE--FS--------RVVTSMR--GTRGYLAPEWLS---
   . |  |. .   .. |  |||  . .  ||| | ||||||.|...  |. |||||. |.    ..        .  .|    ||  |..|| .    
HHPDPWPLRCRMIHEISCGMCYLH--SMNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDN

NMPI---TPKADVYSYGMTLLEIISGR
  ||   ||| ||||..... |. ...
KKPIKVVTPKYDVYSFAIVMWEVLTQK
Kinase SD2b2_e.AA Pkinase_Tyr 74-267 29 2e-25 86.7 Pfam 3-209 (270) Show / Hide 
Range on Protein: 74-267
Range on HMM: 3-209/270
Sequence Identity: 29% (62 aa)

FRKQLGSGGFGEVFKGSIQ------GEAVAVKRLMRFDDKQ------FRAEVSTIGTI-QHMNLVRLRGFCA-DGAL-QRLLVYEFVERGSLDRSLFNRD
| |.||.| ||||.||         .  |||| |    ...      | .|...  .. .| |.||| | |  .|   | ..| |... |.|.  | .. 
FGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR

AENSIVLSWTQRFGIALGTAKGLAYLHEECRDRIIHCDIKPENILLDAEMKPKVGDFGLAKLM-GREFS-RVVTSMRGTRGYLAPEWLSNMPITPKADVY
 |.   |.  .  ....  |||..||..     .|| |.   |.|.. ... |..|||||...   .   |. .. .     .||| ....  | | ||.
-EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVW

SYGMTLLEIIS
|.| .. ||..
SFGVLMWEIFT
TyrKc SD2b2_e.AA TyrKc 72-338 22 3.8e-21 77.49 SMART 1-280 (280) Show / Hide 
Range on Protein: 72-338
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

DGFRKQLGSGGFGEVFKGSIQGEAVAVKRLMRFDDKQFRAEVSTIGTI--QHMNLVRLRGFCADGA------LQRLLVYEFVERGSLDRSL-FNRDAENS
  . |.||.| ||||.||    . |||| |     . |. | .    .  .| |.||| | | ..        . ..| |... |.|.  |  .|.    
ITLGKKLGEGAFGEVYKGTWK-IQVAVKMLKEDAREDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK---

IVLSWTQRFGIALGTAKGLAYLHEECRDRIIHCDIKPENILLDAEMKPKVGDFGLAKLMGRE----FSRVVTSMR---GTRG-----YLAPEWLSNMPIT
  |.. .   ...  |.| .|||.    ..|| |.   |.|....   |..||||..  . .     |  . ...   |...      .||| .     |
--LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFT

PKADVYSYGMTLLEIISGRRNVNVQ-SKQPFYPFWAAQQVRNGEFAKLPDDRLEEWDE-----DELRRAAKTALWCVQDDEINRPSMKTVVQML
.| ||.|.| .. || .          .|.  .. . ..|..|.  . |.. .    .               ..| . |  .||....... .
TKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDY----PMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEIHECF
Kinase SD2b2_e.AA TK 318-338 23 0.005516 4.99 In-house 466-486 (486) Show / Hide 
Range on Protein: 318-338
Range on HMM: 466-486/486
Sequence Identity: 23% (5 aa)

LWCVQDDEINRPSMKTVVQML
. | . |   ||........|
QQCWHYDPEDRPTFSQLHEQL
Kinase SD2b2_e.AA Dicty4-Unclassified 319-338 40 0.007941 5.47 In-house 244-263 (263) Show / Hide 
Range on Protein: 319-338
Range on HMM: 244-263/263
Sequence Identity: 40% (8 aa)

WCVQDDEINRPSMKTVVQML
||  .|   ||.|  ..| |
WCWHNDPNKRPTMNQIIQYL
Kinase SD2b2_e.AA MLK 327-338 50 0.055643 2.82 In-house 280-291 (291) Show / Hide 
Range on Protein: 327-338
Range on HMM: 280-291/291
Sequence Identity: 50% (6 aa)

NRPSMKTVVQML
.|||.. .|| |
KRPSFRQIVQHL
Kinase SD2b2_e.AA Dicty4 326-340 35 0.160348 1.04 In-house 261-277 (277) Show / Hide 
Range on Protein: 326-340
Range on HMM: 261-277/277
Sequence Identity: 35% (6 aa)

INRPSMKTVVQM--LEG
..|||.. ..|   || 
QHRPSFEEIIQRRILEH