Gene RLCK3e-2 (S.moellendorffii)

RLCK3e-2

Species: S.moellendorffii
Alias: RLCK3e-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: RLCK3

Sequence

Name Sequence Type Origin Length Description Download
RLCK3e-2.AA Protein None 414 None Fasta, JSON
RLCK3e-2.NA RNA None 1245 None Fasta, JSON
RLCK3e-2.kin_dom Protein Kinase Domain None 96 None Fasta, JSON

Protein domain

Protein domains of RLCK3e-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase RLCK3e-2.AA TKL 172-407 17 1.3e-10 34.45 In-house 71-364 (364) Show / Hide 
Range on Protein: 172-407
Range on HMM: 71-364/364
Sequence Identity: 17% (55 aa)

EIRQETVNLGSLRRCNVLPLLGFSLTHSY-------------LLLFMP--KLRSLTDVLRNSSLSWSCRCRVAALVARGLSRLHYSREAAATSNGPASSV
....|.. . .||  |.....|...  ..             | . |   .  || ..|      |. ||| |  .|||.. || ..  . |        
FEEEEIMMMSRLRHPNIVQFMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----WHQRCRWALDIARGMNYLHSMNPKWCT--------

VTAVLHGNIRSENVHLLLEEATD-------DSPPTCTPYIADTGFVKLTSMPIFRPDEM--------------ITNTRG----YAAPEVSSGG-------
  ...| .. |.|.  |. |          . . .... |.| |. .  |.     | |               |.|..    . ||||  |        
KPPIIHRDLKSKNI--LVDENWTNVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKV

---------ALTTKSEVYSFGVVLCVLLSGQTDVAALNPV---------ALLKQKLKRFMDPKLEK--------SYNGSQARTIQQTALKCIQRDPMQRP
           ..|. |||||.||. .|....  . ...          . ...  .... | .          . . .  . . . . .| . || .||
GIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRP

DMIRVEAWL
 . ..  .|
SFQEILKRL
S_TKc RLCK3e-2.AA S_TKc 126-407 15 5.8e-08 -60.16 SMART 1-231 (231) Show / Hide 
Range on Protein: 126-407
Range on HMM: 1-231/231
Sequence Identity: 15% (48 aa)

LLELQEPGRVSFHGCLRLGPDSM--QEVSIRKLELTKAVDLLTHLESAEIRQETVNLGSLRRCNVLPLLGFSLTHSYLLLFMPKLR----SLTDVLRNSS
   |.. |. .| |. ... .    ..| | ..                ||.|   | . .  |.  |...  . ..| ..|  .     .| |....  
YEILRKIGKGAF-GKVYKCRHKKTGRIVAIKIIK-------------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRG

-------LSWSCRCRVAALVARGLSRLHYSREAAATSNGPASSVVTAVLHGNIRSENVHLLLEEATDDSPPTCTPYIADTGFVKLTSMPIFRPDEMITNT
       ..    ..... ....|  .|  .                ..|  .  ||  .|| |         .  |.| |. ..           .  |
RHGLRFPFPE-HARFYMYQICCALEYCHSHG----------------IIHRDLKPEN--ILLDE---------HIKICDFGLARQL--------TTFCGT

RGYAAPEVSSGGALTT-KSEVYSFGVVLCVLLSGQTDVAALNPVALLKQKLKRFMDPKLEKSYNGSQARTIQQTALKCIQRDPMQRPDMIRVEA------
. | ||||      .. |. ..|.|..|  .|.|..     .. ...|. .                 .   .   || |.|| .||    . .      
PWYMAPEVL---GYGKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG----------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIK

---WL
   |.
CHPWF
TyrKc RLCK3e-2.AA TyrKc 121-407 16 4e-07 -107.41 SMART 1-280 (280) Show / Hide 
Range on Protein: 121-407
Range on HMM: 1-280/280
Sequence Identity: 16% (52 aa)

DVAVNLLELQEPGRVSFHGCLRLGPDSMQEVSIRKLELTKAVDLLTHLESAEIRQETVNLGSL--RRCNVLPLLGFSLTH-------SYLLLFMP--KLR
 .    |   . |.| ..| ..      ..| . .|   .          .....|   . .|  .  |.. |.|  ...         |.. |   .. 
ITLGKKLGEGAFGEV-YKGTWK------IQVAVKMLKEDA---------REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHG

SLTDVLRNSS--LSWSCRCRVAALVARGLSRLHYSREAAATSNGPASSVVTAVLHGNIRSENVHLLLEEATDDSPPTCTPYIADTGFVKLTSMP---IFR
.| | ||..   |...  .  .  .|.| . ||                   . |  .   |. .  .          |  |.| |  .          .
DLKDYLRKHRPKLCMKDLLSFCWQIACGMEYLHSK----------------NCIHRDLAARNCLVGENH---------TVKISDFGLSRDIYDDDQQGES

PDEMIT----NTRG-----YAAPEVSSGGALTTKSEVYSFGVVLCVLLS-GQTDVAA-----LNPVALLKQKLKRFMDPKLEK----SYNGSQARTIQQT
 |   .    ....       |||.   |  |||| |.||||..  ... ||.         ...  ....  .... |. .     |. .  .   |  
KDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-I

ALKCIQRDPMQRPDMIRVEAWL
 ..| ..|| .|| .  .   .
MKQCWHEDPEDRPTFSEIHECF
Kinase RLCK3e-2.AA Src-Echino1 315-407 24 4e-06 16.86 In-house 163-252 (252) Show / Hide 
Range on Protein: 315-407
Range on HMM: 163-252/252
Sequence Identity: 24% (23 aa)

YAAPEVSSGGALTTKSEVYSFGVVLCVLLS-GQTDVAALNPVALLKQKLKRFMDPKLEKSYNGSQARTIQQT-ALKCIQRDPMQRPDMIRVEAWL
. |||    |  | ||.|.|||...  ..  |.     .    .|.|  . .  ||...      .  . .   .||  .|| ||| .  .  ..
WTAPEAALYGRFTIKSDVWSFGILMTEMVTFGRYPYPGMMNREVLDQVDRGYRMPKMHHC-----PDSLYMMCMMKCWHKDPQQRPTFEFLHDFF
Kinase RLCK3e-2.AA Ciliate-E3 315-343 41 5e-06 15.14 In-house 174-202 (202) Show / Hide 
Range on Protein: 315-343
Range on HMM: 174-202/202
Sequence Identity: 41% (12 aa)

YAAPEVSSGGALTTKSEVYSFGVVLCVLL
|||||.   ..    |  || |.|.| | 
YAAPEQNDQQQISKESDYYSVGAVFCQLC
Kinase RLCK3e-2.AA ARK 308-339 34 7e-06 17.66 In-house 163-205 (280) Show / Hide 
Range on Protein: 308-339
Range on HMM: 163-205/280
Sequence Identity: 34% (15 aa)

MITNTRGYAAPEVSS-----------GGALTTKSEVYSFGVVL
.. .|  | ||||.            |   |||| |||.|...
KMRGTFAYCAPEVYYFQDIDDDYVSNGKHYTTKSDVYSMGIIM
Kinase RLCK3e-2.AA RSKL 312-347 41 1e-05 8.04 In-house 341-376 (436) Show / Hide 
Range on Protein: 312-347
Range on HMM: 341-376/436
Sequence Identity: 41% (15 aa)

TRGYAAPEVSSGGALTTKSEVYSFGVVLCVLLSGQT
|..| ||||..   ||  .   |.|.||  || |..
TNMYCAPEVGQIWELTEACDWWSYGAVLYELLCGMS
Kinase RLCK3e-2.AA MOS 312-339 42 3.4e-05 12.94 In-house 201-228 (299) Show / Hide 
Range on Protein: 312-339
Range on HMM: 201-228/299
Sequence Identity: 42% (12 aa)

TRGYAAPEVSSGGALTTKSEVYSFGVVL
| .| |||.  | ..|.|. .||||. .
TCTYMAPELLCGDTPTPKADIYSFGITM
Kinase RLCK3e-2.AA Pkinase 312-407 17 3.8e-05 19.27 Pfam 174-293 (293) Show / Hide 
Range on Protein: 312-407
Range on HMM: 174-293/293
Sequence Identity: 17% (21 aa)

TRGYAAPEVSS-GGALTTKSEVYSFGVVLCVLLSGQTDVAAL------NPVALLKQKLKRFMDPKLEKSYNGS---------------QARTIQQTALKC
|..|.||||   |   ..|. ..|.|..|  .|.|..           .. .........  .   ......|               . .. ..   .|
TPWYMAPEVIRGGQYYGPKVDMWSCGCILYEMLCGRPPFPGHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWC

IQRDPMQRPD--MIRVEAWL
...|| .||    |    |.
LCKDPKKRPTAEQILQHPWF
Kinase RLCK3e-2.AA TKL-Unique 289-339 32 6.7e-05 13.43 In-house 158-218 (290) Show / Hide 
Range on Protein: 289-339
Range on HMM: 158-218/290
Sequence Identity: 32% (20 aa)

IADTGFVKLTS----MPIFRP-----DEMITNTRGYAAPEVSSG--GALTTKSEVYSFGVVL
|.| |..|. |    |.. ..     .. ....| ..|||| ..     ..||.|||||.||
ICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFR-WMAPEVLRMNFCQYSEKSDVYSFGIVL
Kinase RLCK3e-2.AA Ciliate-E2-Unclassified 289-346 27 8.3e-05 12.64 In-house 188-267 (352) Show / Hide 
Range on Protein: 289-346
Range on HMM: 188-267/352
Sequence Identity: 27% (22 aa)

IADTGFVK------------LTSMPIFRPDEMITN--TRGYA----APEVSSGGALT----TKSEVYSFGVVLCVLLSGQ
|.| |. |            .. | |.....| |.  | .|     ||||  |         |. ..|.||.|  .| |.
IIDFGISKKYQQNNNCDTNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGY
Kinase RLCK3e-2.AA C8 312-339 30 8.9e-05 12.63 In-house 194-226 (226) Show / Hide 
Range on Protein: 312-339
Range on HMM: 194-226/226
Sequence Identity: 30% (10 aa)

TRGYAAPEVSSG-----GALTTKSEVYSFGVVL
| .| |||. ..        . .| ..| |.||
TWAYFAPEIEKKQDNQYKQYRIQSDLFSVGLVL
Kinase RLCK3e-2.AA TESK 317-340 54 0.000383 8.48 In-house 204-227 (292) Show / Hide 
Range on Protein: 317-340
Range on HMM: 204-227/292
Sequence Identity: 54% (13 aa)

APEVSSGGALTTKSEVYSFGVVLC
||||  |   . |. |.|||.|||
APEVLRGEWYDEKADVFSFGIVLC
Kinase RLCK3e-2.AA TESK 210-240 36 0.000774 7.5 In-house 79-111 (292) Show / Hide 
Range on Protein: 210-240
Range on HMM: 79-111/292
Sequence Identity: 36% (12 aa)

SLTDVLR--NSSLSWSCRCRVAALVARGLSRLH
.|...|   .  |||  . . |  .|||.| ||
CLEQLLADSELHLSWTQKIHLAYDIARGMSYLH