Gene LRR6_a-2 (S.moellendorffii)

LRR6_a-2

Species: S.moellendorffii
Alias: LRR6_a-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR6

Sequence

Name Sequence Type Origin Length Description Download
LRR6_a-2.AA Protein None 1087 None Fasta, JSON
LRR6_a-2.NA RNA None 3264 None Fasta, JSON
LRR6_a-2.kin_dom Protein Kinase Domain None 205 None Fasta, JSON

Protein domain

Protein domains of LRR6_a-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRR_1 LRR6_a-2.AA LRR_1 169-191 25 4.188571 4.54 Pfam 1-26 (26) Show / Hide 
Range on Protein: 169-191
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

HLTTIQLTRC---GLMLEIPSE-LCEL
.|... | .|    |  .||.. .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 193-215 40 0.001325 16.95 Pfam 1-26 (26) Show / Hide 
Range on Protein: 193-215
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

RLTELDMSQ-N--SLFGPIPPC-LGSL
.|..||.|  |  .| | |||  . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 217-239 44 0.00467 15.01 Pfam 1-26 (26) Show / Hide 
Range on Protein: 217-239
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

NLTELLLFQ-N--NLSGKIPAS-LVQL
||..| |   |  ||.|.|| | . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 263-285 44 0.000105 20.86 Pfam 1-26 (26) Show / Hide 
Range on Protein: 263-285
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

KIEVLDLSS-N--NLTGALPDV-IANL
....||||. |  |||| .|.  . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 241-262 37 0.448707 7.98 Pfam 1-26 (26) Show / Hide 
Range on Protein: 241-262
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

LLKSLVLYA-N--NLEGPIPP--LQGN
 |..| |   |  ||.| |||  . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 287-308 25 0.059936 11.08 Pfam 1-26 (26) Show / Hide 
Range on Protein: 287-308
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

SLRVLSAAN-N--SLSGVLPR--FASS
.|..|.  . |  .|.| .|   | . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 310-332 37 0.11474 10.08 Pfam 1-26 (26) Show / Hide 
Range on Protein: 310-332
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

RIQELDLST-N--EFYGPLQPT-ICNL
..|.||||  |   . | ..|  . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 334-356 25 13.829889 2.7 Pfam 1-24 (26) Show / Hide 
Range on Protein: 334-356
Range on HMM: 1-24/26
Sequence Identity: 25% (7 aa)

RLSVLRLSR-N--YLN-SDFLLTPN-CF
.| .| ||. |   |  .   . |. . 
NLQHLDLSGCNCCNLTGH---IPPSCF-
LRR_1 LRR6_a-2.AA LRR_1 358-380 33 0.023073 12.55 Pfam 1-26 (26) Show / Hide 
Range on Protein: 358-380
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

SITELDLHA-N--QLYGRLPPG-LLSL
....|||   |  .| | .||. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 382-403 29 0.002553 15.94 Pfam 1-26 (26) Show / Hide 
Range on Protein: 382-403
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

TLERIDLSM-N--QFTGSLPA--LGHN
.|...|||  |  ..||..|   . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 406-427 25 1.551006 6.07 Pfam 1-26 (26) Show / Hide 
Range on Protein: 406-427
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

GLTSMELSN-N--WLTGTLED--LRFN
 |..  ||. |   |||.. .  .   
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 431-453 40 0.073302 10.77 Pfam 1-26 (26) Show / Hide 
Range on Protein: 431-453
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

NLGGLDLSH-N--DIGGTIPGY-ISNC
||  ||||. |   . |.||   . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 455-477 33 0.002536 15.95 Pfam 1-26 (26) Show / Hide 
Range on Protein: 455-477
Range on HMM: 1-26/26
Sequence Identity: 33% (9 aa)

GLNVLNLND-N--SFQGTIPWE-LGNL
 | .|.|.. |  ...|.|| . . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 479-501 37 0.364515 8.3 Pfam 1-26 (26) Show / Hide 
Range on Protein: 479-501
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

GLGTVMLRG-N--RLGGELPES-LGNL
 | .  |.| |  .| |..|.| . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 503-526 29 0.62083 7.48 Pfam 1-26 (26) Show / Hide 
Range on Protein: 503-526
Range on HMM: 1-26/26
Sequence Identity: 29% (8 aa)

VLTVLELSE-N--SFTGKLESTGINRL
 |..| ||  |  ..||.. .  .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 528-550 25 65.151416 0.31 Pfam 1-26 (26) Show / Hide 
Range on Protein: 528-550
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

YLNLLLLRS-N--AFDGLIPNW-IGSF
 |  | |.. |   . | ||.. . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 553-577 25 2.911751 5.1 Pfam 1-26 (26) Show / Hide 
Range on Protein: 553-577
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

FLSGIDLSH-N--RFSGQLSHDIDMTGL
 |  .|||. |  ...|.....    .|
NLQHLDLSGCNCCNLTGHIPPS-CF-NL
LRR_1 LRR6_a-2.AA LRR_1 615-637 40 0.000507 18.43 Pfam 1-26 (26) Show / Hide 
Range on Protein: 615-637
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

QISFLDLSS-N--FLEGELPDS-FGNM
..  ||||. |   |.|..|.| | |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 639-661 44 0.00026 19.46 Pfam 1-26 (26) Show / Hide 
Range on Protein: 639-661
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

RLMYLTLSG-N--RFSGKIPAS-FGRL
.| .| ||| |  ...|.|| | |  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 663-685 37 0.007502 14.28 Pfam 1-26 (26) Show / Hide 
Range on Protein: 663-685
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

VLEGLDLTR-N--RLSDSIPET-LVNL
 |. ||| . |  .|...||.  . ||
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR6_a-2.AA LRR_1 687-704 33 3.168203 4.97 Pfam 1-21 (26) Show / Hide 
Range on Protein: 687-704
Range on HMM: 1-21/26
Sequence Identity: 33% (7 aa)

KLGYFNVSY-N--NLSGTVPS
.| . ..|. |  ||.|..|.
NLQHLDLSGCNCCNLTGHIPP
Kinase LRR6_a-2.AA TKL 811-1079 19 4.5e-55 189.27 In-house 1-364 (364) Show / Hide 
Range on Protein: 811-1079
Range on HMM: 1-364/364
Sequence Identity: 19% (76 aa)

IGTGASSTVYKGRLAR--------DGKSVAIKVFRPRKDDWNSATEIE-----------------------------ALSRIKHRNLVRFLGVCWEDDC-
|| |....||||..          .|| ||.|.|. . || .. .. |                              .||..| |.|.|.|.| . .| 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------KALVFDLMPNGTLDSHLHDVSEKVKVFTMKQRLKVALGVAYAVRYLHHEL----NAGEAIVHGDLKPSNIFLDDEME-----------
             ..| ...|.|.| ..||          . ||.. ||..| .. ||| .         .|.| |||..||..|. ..           
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---AHVGDFGAARLLQAVNAYEDS----------------KSELRGSIGYMPPELAVSN----------------KLCAKTDVYSYGIILLEMLTGKRPT
   . ..||| .| ..  .  .|.                ..  .|....|.||.   .                .   |.||||.||.| |.||..|  
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--

NSMFKDGRTLHDWARSSFPNLEILLD------------PTLLSQEEPLEFP--------------VARELFRLGILCSSEQREHRPTMDFVTSML
                  |  ..  .                .  .... |              . ... .|   | ..  | ||... ... |
------------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Pkinase LRR6_a-2.AA Pkinase 805-1007 24 2.6e-46 164.84 Pfam 1-209 (293) Show / Hide 
Range on Protein: 805-1007
Range on HMM: 1-209/293
Sequence Identity: 24% (54 aa)

FDAKNIIGTGASSTVYKGRLARDGKSVAIKVFRPRKDDWNSA------TEIEALSRIKHRNLVRFLGVCWEDDCKALVFDLMPNG----TLDSHLH-DVS
.  . .|| |....|||..   .|| ||.|... |.....        .||. . |..| | ||..... ..|   .|......|     | .... . .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

EKVKVFTMKQRLKVALGVAYAVRYLHHELNAGEAIVHGDLKPSNIFLDDEMEA----HVGDFGAARLLQAVNAYEDSKSELRGSIGYMPPELAV-SNKLC
 ..  |....  .... .. .. |.| .      |.| ||||.||..|....     ...||| |....    ..   . . |...||.||.   ...  
GCFY-FSEWECKFYMYQILRGLEYCHSM-----GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS--MTTFCGTPWYMAPEVIRGGQYYG

AKTDVYSYGIILLEMLTGK
 | |..|.|.|| |||.|.
PKVDMWSCGCILYEMLCGR
Kinase LRR6_a-2.AA IRAK 805-1009 32 5.2e-40 139.23 In-house 1-223 (317) Show / Hide 
Range on Protein: 805-1009
Range on HMM: 1-223/317
Sequence Identity: 32% (72 aa)

FDAKNIIGTGASSTVYKGRLARDGKSVAIK-VFRPRKDDWNSA-----T---EIEALSRIKHRNLVRFLGVCWEDDCKALVFDLMPNGTLDSHLHDVSEK
|.. | || |.  .||.|..   .  .|.| .   ..  ||.      .   |.....|. | |.| ..| | | .|  ||...||||.|   |.     
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

VKV--FTMKQRLKVALGVAYAVRYLHHELNAGEAIVHGDLKPSNIFLDDEMEAHVGDFGAARLLQAVNAYEDSKS------ELRGSIGYMPPELAV--SN
.     .  ||.....| | ....| |..  . .| ||| |..|| ||. ...  .|||..|  .   . |....       .||.  |||||     . 
CPPKPLSWHQRCSICWGTACGIQFL-HQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQG

KLCAKTDVYSYGIILLEMLTGKRP
.|  |||||| || ||| ||| |.
QLTKKTDVYSFGIVLLEVLTGCRA
Kinase LRR6_a-2.AA MLK 805-1009 26 5.2e-35 118.93 In-house 1-235 (291) Show / Hide 
Range on Protein: 805-1009
Range on HMM: 1-235/291
Sequence Identity: 26% (65 aa)

FDAKNIIGTGASSTVYKGRLARDG---KSVAIKVFRPRK----D----DWNSATEIEALSRIKHRN----LVRFLGVCWEDDC-KALVFDLMPNGTLDSH
.. . .|| |..  |.|||        | ||.| .| |.    |    .|.  .|.. |....|.|     ..|.||| .. |  ..|   ...| | . 
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LHDVSEKVK----------VFTMKQRLKVALGVAYAVRYLHHELNAGEAIVHGDLKPSNIFLDD------EMEAHVGDFGAARLLQAVNAYEDS-KSELR
||. . |            | .. . .. || .| .. ||| ..    .|.| |||..|| .|.      .. . . |||..| ..     . . .   .
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAP--KPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQM---C-TNMMSNA

GSIGYMPPEL---AVSNKLCAKTDVYSYGIILLEMLTGKRP
|.  .| ||    . ..|   | ||.|.|..| ||||.. |
GTYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase LRR6_a-2.AA TKL-Unique 807-1009 27 2e-33 115.27 In-house 1-233 (290) Show / Hide 
Range on Protein: 807-1009
Range on HMM: 1-233/290
Sequence Identity: 27% (67 aa)

AKNIIGTGASSTVYKGRLARDGKSVAIKVFRPRKDDWNSA------TEIEALSRIK-HRNLVRFLGVCW----EDDCKALVFDLMPNGTLDSHLHD---V
  | ||.|....||||  .  |..||||.| | . | ..        |.  ..... | |.|.. |.|           .| . .| |.|...||.    
FWNKIGEGGYGQVYKGKWR--GYPVAIKQFHP-NEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNN

S---EKVKVFTMKQRLKVALGVAYAVRYLHHELNAGEA-IVHGDLKPSNIFLDDE-----MEAHVGDFGAARLLQ--AVNAYEDS----KSELRGSIGYM
.   .. . ..|.||.| |. .| .  ||||.    |. | |.|||.||. .| .     . . . ||| ....     . .  .    ...  ||. .|
NNNNNNNCKLNMQQRVKMAIDIAQGMYYLHHC----EPPIIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWM

PPELAVS--NKLCAKTDVYSYGIILLEMLTGKR------P
.||.  .  ..   | ||||.||.| |..|.|.      |
APEVLRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase LRR6_a-2.AA S_TKc 805-1079 22 2.8e-33 117.79 SMART 1-231 (231) Show / Hide 
Range on Protein: 805-1079
Range on HMM: 1-231/231
Sequence Identity: 22% (66 aa)

FDAKNIIGTGASSTVYKGRLARDGKSVAIKVFRPRKDDWNSATEIEALSRIKHRNLVRFLGVCWEDDCKALVFDLMPN--GTLDSHLHDVSEKV--KVFT
..  ..|| || ..|||.|  ..|. ||||. .      .   ||. |.. .| |.|....|. . |.  .|......  |.| .....   .   ..|.
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

MKQRLKVALGVAYAVRYLHHELNAGEAIVHGDLKPSNIFLDDEMEAHVGDFGAARLLQAVNAYEDSKSELRGSIGYMPPELAVSNKLCA-KTDVYSYGII
  .  ...  .. |. |.|   .    |.| ||||.||.||.  .  ..||| ||.|          . . |.  ||.||.    .    | |..| |.|
E-HARFYMYQICCALEYCHSH-G----IIHRDLKPENILLDE--HIKICDFGLARQL----------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LLEMLTGKRPTNSMFKDGRTLHDWARSSFPNLEILLDPTLLSQEEPLEFPVARELFRLGILCSSEQREHRPTMDFVTS---------ML
| |||.|. |      .  .. .  .                          .|.  .   |     |.|||   .            .
LYEMLCGYPPFP----QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR6_a-2.AA STE 805-1009 20 3.6e-28 96.64 In-house 1-267 (359) Show / Hide 
Range on Protein: 805-1009
Range on HMM: 1-267/359
Sequence Identity: 20% (57 aa)

FDAKNIIGTGASSTVYKGRLAR---------------DGKSVAIKVFRPRKDD----------------WNSA---TEIEALSRIK--HRNLVRFLGVCW
..   .|| ||. ||||..                   |. .|||. . ....                 .      ||. ... .  | | |...| . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

ED-------DCKALVFDLMPNGTLDSHLHDVSEKVK----------VFTMKQRLKVALGVAYAVRYLHHELNAGEAIVHGDLKPSNIFLDDEMEAHVGDF
 .       |   ..  .|..|.||. .. . .. |          .|  .|  ...  .  .  |..|...    |.| |.||.||.|     .   ||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH----IIHRDIKPANILL-----VKLCDF

GAARLLQAVNA------------YEDSKS-ELRGSIGYMPPELAVSNKLC------AKTDVYSYGIILLEMLTGKRP
| .  |.  .|              ..|.  . |.  .| ||    |. .      .| |..| |. ..||.||| |
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
Kinase LRR6_a-2.AA Ciliate-E2 805-1009 18 4.8e-28 93.34 In-house 1-295 (365) Show / Hide 
Range on Protein: 805-1009
Range on HMM: 1-295/365
Sequence Identity: 18% (58 aa)

FDAKNIIGTGASSTVYKGRLARDG-----------------------KSVAIKVFRPR-KDDWNSATEIE--------------ALSRIKHRNLVRFLGV
..  ..||.|. ..|||..  ...                       | .|.|..... .  ...   |                |....| |....  .
YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC

CW--EDDCKALVFDLMPNGTLDSHLHDV---------SEKVKVFTMKQRLKVALGVAY---------------AVRYLHHELNAGEAIVHGDLKPSNIFL
     |..  ||...   |.| ... .          . . | ||.|.....   ...               |..||| . |    |.| |.||.||..
FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEK-D-KYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN----IIHRDIKPENILF

DDEMEAHVGDFGAARLLQAV----------NAYEDSKSE-------------------LRGSIGYMPPELAVSNKLC---------AKTDVYSYGIILLE
       . ||| .. ..            . | . |..                   . |. |||.||   . |            | |..| |.|| |
-----IKIIDFGLSKKYDDDNQNRTHKQQCKWYMF-KNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYE

MLTGKRP
||.||.|
MLFGKPP
Kinase LRR6_a-2.AA TK 805-1009 15 9.2e-28 89.52 In-house 1-394 (486) Show / Hide 
Range on Protein: 805-1009
Range on HMM: 1-394/486
Sequence Identity: 15% (60 aa)

FDAKNIIGTGASS---TVYKGRLARDGK-------------------------SVAIKVFR---PRKDDWNSA-------------TEIEALSRIK----
    . .| |.     .||||.. ....                          ||.|. .   .  ..   .              | |...  .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HRNLVRFLGVCWEDDCK------------ALVFDLMPNGT----LDSHLHDVSEKVKV-----------------------------------------
 | |.||..||| ....|             .|  .||.|     |...|.. ..| .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------FTMKQRLKVALGVAYAVRYLHHE---LNAGEAI---VHGDLKPSNIFLDDEME-----------AHVGD
                               .||.|.|  .. .| . .|||     .     |   ||.||   |. .....            . ..|
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEF-----IQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIAD

FGAAR-----LLQAVNAYEDSKSELRGSIGY--------------------------MPPELAV---------SNKLCAKTDVYSYGIILLEMLT-GKRP
|| .|     |  ...  .|  .   .. |                           |.||             .|   |.||.|.|. . |..| |. |
FGLSRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase LRR6_a-2.AA RAF 805-1016 24 2.4e-26 82.21 In-house 1-229 (282) Show / Hide 
Range on Protein: 805-1016
Range on HMM: 1-229/282
Sequence Identity: 24% (57 aa)

FDAKNIIGTGASSTVYKGRLARDGKSVAIKVFRPRKDDWNS----ATEIEALSRIKHRNLVRFLGVCWEDD--CKALVFDLMPNGTLDSHLHDVSEKVKV
.. .. ||.|   |||.|.   |     ..|  |  ..         |. .. .  | | . |.|   ..     | | .     .|  |.| |.|  . 
VMVMTRIGSGSFGTVYRGHWHGDVAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILLFMGYMSKPQTNTYAIVTQWCEHSSLYHHIH-VQETREK

FTMKQRLKVALGVAYAVRYLHHELNAGEAIVHGDLKPSNIFLDDEMEAHVGDFGAARLLQAVN-AYEDSKSELRGSIGYMPPELAV--------------
| | . . ... |. .  |||        |.| |||  ||||...|   .|||| ... .  .   .     . ..| .| || .               
FDMHWLIDISRQVCQGMDYLHA-----KNIIHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQD

SNKLCAKTDVYSYGIILLEMLTGKRPT--NSMFKD
 |    . ||||.||.. |..|.. |.  ..  .|
ENPYSFQSDVYSFGIVMYELMTRHMPYGCHIWNRD
Kinase LRR6_a-2.AA TK-Unique 805-1005 23 1.4e-25 85.23 In-house 1-234 (294) Show / Hide 
Range on Protein: 805-1005
Range on HMM: 1-234/294
Sequence Identity: 23% (56 aa)

FDAKNIIGTGASSTVYKGRLARDG------KSVAIKVFRPRKDDWN---SATEIEALSRIK-HRNLVRFLGVCWEDD-CKALVFDLMPNGTLDSHLHDVS
.  ...||.|| ..|..| . ..       |.||.|  . . .|        ||. .. .. | |.|..||.| ..|    ...  .|.|.|...|.   
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

-EKVKV---------------------FTMKQRLKVALGVAYAVRYLHHELNAG--EAIVHGDLKPSNIFLDDEMEAHVGDFGAARLLQAVNAYEDSKSE
 ... .                      ..|. .  | ..| .  ||     |.  . |||.||  .|..| .  .. ..||| || ... ..|. ..|.
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYL-----ASQRKKIVHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQ

LRGSIGYMPPELAV--SNKL-CAKTDVYSYGIILLEMLT
 | .| .|.||      .     |.||.|.|... |..|
GRIPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase LRR6_a-2.AA Ciliate-E2-Unclassified 805-1009 18 1.6e-24 81.99 In-house 1-269 (352) Show / Hide 
Range on Protein: 805-1009
Range on HMM: 1-269/352
Sequence Identity: 18% (52 aa)

FDAKNIIGTGASSTVYKGRLARDG-------KSVAIKVF-----RPRKDDWNSATEIEAL----------------SRIKHRNLVRFLGVCWEDDCKALV
.    .||.|. ..||| .   ..       .......      .   . .|...|.. .                . ..| ..|... .   ...  .|
YKIIKQIGQGGFGKVYKCQHKKQKQYYAMKYMKKIQIYKQKQIMNKD-EIMNEMKEMNNKKKYHQRKYNKIMQQILLNHPHPFIVKMFYCFQDKQNIYIV

FDLMPNGTLDSHLHDVSE------------KV-KVFTMKQRL-----KVALGVAYAVRYLHHELNAGEAIVHGDLKPSNIFLDDEM---EAHVGDFGAAR
 .....|.|  .. . .             |  | || .| .     . .  .  .  ||||..|    |.| |.||.||..|...   .  . ||| ..
MEYCEGGDLWQYIKKRKKQKQKGNDLFHNMKQRKIFTEQQAKYKKAKFYFAQILQGLEYLHHKNN----IIHRDIKPENILFDNNGKNYYIKIIDFGISK

LLQAVNAYEDSK-------------SELRGSIGYM----PPELAVSNKLC----AKTDVYSYGIILLEMLTGKRP
 .|  | ..  .             .   |...||    .||.  ...       | |..| |.|| |||.|..|
KYQQNNNCD-TNQQQKMQIWKQQMMWTFCGTPNYMPQYTAPEVLQGQNYDHSKAYKCDIWSLGVILYEMLFGYYP
Kinase LRR6_a-2.AA Pkinase_Tyr 805-1079 22 6.1e-21 71.54 Pfam 1-270 (270) Show / Hide 
Range on Protein: 805-1079
Range on HMM: 1-270/270
Sequence Identity: 22% (67 aa)

FDAKNIIGTGASSTVYKGRLA----RDGKSVAIKVFRP----R---KDDWNSATEIEALSRI-KHRNLVRFLGVCW-EDDC--KALVFDLMPNGTLDSHL
      .| ||  .||||..      ..  ||.|. ..    .   ..|  .  |.. .. . .| |.||..|||  ...     .|. .||.| |...|
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMR--EAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYL

HDVSEKVKVFTMKQRLKVALGVAYAVRYLHHELNAGEAIVHGDLKPSNIFLDDEMEAHVGDFGAARLLQAVNAYE-DSKSELRGSIGYMPPELAVSNKLC
.. .|  . .|||. |. .. .| .  ||.        ..| ||   |. ..... . ..||| ||..     |   .... .  |  |.||    .|  
RKHREDKQPLTMKDLLQMCWQIAKGMEYLESKN-----CIHRDLAARNCLVTENNVVKICDFGLARDI-YNDDYYYRKRGGGKLPIKWMAPECINYGKFT

AKTDVYSYGIILLEMLT-GKRPTNSMFKDGRTLHDWARSSFPNLEILLD-PTLL-SQEEPLEFPV--ARELFRLGILCSSEQREHRPTMDFVTSML
 |.||.|.|. . |..| |. |                  .|..    .   ..  . . .. |     |. .|  .|  .. |.|||.  . ..|
TKSDVWSFGVLMWEIFTYGEQP-----------------TYPGM-SNEEVYEYIYEDGYRMPCPENCPDEIYDLMKQCWHYDPEDRPTFSEIHEQL
Kinase LRR6_a-2.AA TyrKc 805-1079 22 2.4e-16 41.65 SMART 1-280 (280) Show / Hide 
Range on Protein: 805-1079
Range on HMM: 1-280/280
Sequence Identity: 22% (67 aa)

FDAKNIIGTGASSTVYKGRLARDGKSVAIKVFRPRKDDWNS-ATEIEALSRI--KHRNLVRFLGVCWED-------DCKALVFDLMPNGTLDSHLHDVSE
   . ..| ||  .||||..      ||.|. .. .        |.. ....  .| |.||..||| ..       .   .|. .||.| |...|..  .
ITLGKKLGEGAFGEVYKGTWK---IQVAVKMLKEDA--REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

KVKVFTMKQRLKVALGVAYAVRYLHHELNAGEAIVHGDLKPSNIFLDDEMEAHVGDFGAARLLQAV------NAYEDSKS--ELR--GSIGYMPPELAVS
|   ..||. |. .. .|   .|||.       ..| ||   |. ....  . ..||| .| .           | ..|.    .    |  |.||    
K---LCMKDLLSFCWQIACGMEYLHSK-----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

NKLCAKTDVYSYGIILLEMLT-GKRPTNSM---FKDGRTLHDWARSSFPNLEILLDPTLLSQEEPLEFP-----VARELFRLGILCSSEQREHRPTMDFV
.|   |.||.|.|. . |..| |. |   |   ... . .          .| . .   . | .  . |        |....   |  |. | |||.  .
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEV----------IEYVKQGYRMPQPPNDY-PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

TSML
 . .
HECF