Gene LRR6_c (S.moellendorffii)

LRR6_c

Species: S.moellendorffii
Alias: LRR6_c
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR6

Sequence

Name Sequence Type Origin Length Description Download
LRR6_c.AA Protein None 79 None Fasta, JSON
LRR6_c.NA RNA None 240 None Fasta, JSON
LRR6_c.kin_dom Protein Kinase Domain None 65 None Fasta, JSON

Protein domain

Protein domains of LRR6_c.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase LRR6_c.AA IRAK 1-57 43 5.6e-20 67.6 In-house 106-161 (317) Show / Hide 
Range on Protein: 1-57
Range on HMM: 106-161/317
Sequence Identity: 43% (25 aa)

LPWTVRMNVVQGVANALSYLHEEAASTGPIIHRDIKPANIFLDQNMEAHLGDFGIAR
|.|  |  . .| |... .||.    | ||||.|||.||| |||.... ..||| .|
LSWHQRCSICWGTACGIQFLHQNHPCT-PIIHGDIKSANILLDQHFTPKICDFGLHR
Kinase LRR6_c.AA TKL 3-59 28 5.4e-16 54.08 In-house 131-204 (364) Show / Hide 
Range on Protein: 3-59
Range on HMM: 131-204/364
Sequence Identity: 28% (21 aa)

WTVRMNVVQGVANALSYLHEEA--ASTGP--IIHRDIKPANIFLDQNME--------------AHLGDFGIARNL
| .|.. ....| ...||| .   ..| .  |||||.|..||..|.|..              . ..|||..|..
WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICDFGLSRFM
Kinase LRR6_c.AA Pkinase 13-77 28 4.4e-14 50.89 Pfam 117-177 (293) Show / Hide 
Range on Protein: 13-77
Range on HMM: 117-177/293
Sequence Identity: 28% (20 aa)

VANALSYLHEEAASTGPIIHRDIKPANIFLDQNMEA----HLGDFGIARNLRLESSMHWESKLKGSIGY
.. .| |.|..      |||||.||.||..|.|..     ...|||.|. .. . . .  . . |...|
ILRGLEYCHSM-----GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWY
Kinase LRR6_c.AA NEK 16-57 45 9.4e-13 41.61 In-house 126-171 (286) Show / Hide 
Range on Protein: 16-57
Range on HMM: 126-171/286
Sequence Identity: 45% (21 aa)

ALSYLHEEAASTGPIIHRDIKPANIFLDQNME----AHLGDFGIAR
|| |.|..    . |.||||||.||||. |      . .|||||..
ALKYMHDRKGPQRKILHRDIKPQNIFLTKNNNDYHNVKIGDFGISK
Kinase LRR6_c.AA NEK8 16-65 33 2.3e-12 31.49 In-house 131-176 (278) Show / Hide 
Range on Protein: 16-65
Range on HMM: 131-176/278
Sequence Identity: 33% (17 aa)

ALSYLHEEAASTGPIIHRDIKPANIFLDQN-MEAHLGDFGIARNLRLESSM
|....|..      | |||.|..|||..   |   .|||||.  .  ...|
AVHHMHQHN-----ILHRDLKTQNIFMTRHRMVVKIGDFGISKIMNTKYHM
Kinase LRR6_c.AA NEK2 30-64 29 4.9e-12 36.69 In-house 146-219 (319) Show / Hide 
Range on Protein: 30-64
Range on HMM: 146-219/319
Sequence Identity: 29% (22 aa)

IIHRDIKPANIFLDQNME---------------------------------------AHLGDFGIARNLRLESS
|.||||||||||||..                                         . ||||| || |. ..|
ILHRDIKPANIFLDYDHNDYNINEQVDGHEEVNSNYYRDHRVNSGKRGSPMDYSQVVVKLGDFGLARMLNHDTS
Kinase LRR6_c.AA LISK 1-57 36 1.2e-11 33.89 In-house 98-153 (296) Show / Hide 
Range on Protein: 1-57
Range on HMM: 98-153/296
Sequence Identity: 36% (22 aa)

LPWTVRMNVVQGVANALSYLHEEAASTGPIIHRDIKPANIFLDQN----MEAHLGDFGIAR
|||..|..   ..| ..||||.       ||||| |  |. ...|     .. ..||| ||
LPWPQRVKIALDIACGMSYLHSMN-----IIHRDLKSKNCLVRENDNNQWRIKVCDFGFAR
Kinase LRR6_c.AA PLK-Unclassified 5-56 46 1.3e-11 39.62 In-house 108-153 (264) Show / Hide 
Range on Protein: 5-56
Range on HMM: 108-153/264
Sequence Identity: 46% (24 aa)

VRMNVVQGVANALSYLHEEAASTGPIIHRDIKPANIFLDQNMEAHLGDFGIA
|.  ..| ...|| |||        ||||| |..||||. |||  ..||| |
VKCYTYQ-IVQALKYLHQNR-----IIHRDLKLGNIFLNDNMEVKICDFGLA
Kinase LRR6_c.AA PLK 13-56 45 1.4e-11 34.05 In-house 109-147 (258) Show / Hide 
Range on Protein: 13-56
Range on HMM: 109-147/258
Sequence Identity: 45% (20 aa)

VANALSYLHEEAASTGPIIHRDIKPANIFLDQNMEAHLGDFGIA
....| |||.       |||||.|..|.||. ||.  .|||| |
IVQGLKYLHQHR-----IIHRDLKLGNLFLNDNMHVKIGDFGLA
Kinase LRR6_c.AA PLK2 17-56 50 2.4e-11 32.52 In-house 116-150 (257) Show / Hide 
Range on Protein: 17-56
Range on HMM: 116-150/257
Sequence Identity: 50% (20 aa)

LSYLHEEAASTGPIIHRDIKPANIFLDQNMEAHLGDFGIA
| |||.       ||||| |. | |.  |||   |||| |
LRYLHQQC-----IIHRDLKLGNFFINDNMEVKIGDFGLA
Kinase LRR6_c.AA STE 9-59 40 2.6e-11 36.31 In-house 156-197 (359) Show / Hide 
Range on Protein: 9-59
Range on HMM: 156-197/359
Sequence Identity: 40% (21 aa)

VVQGVANA-LSYLHEEAASTGPIIHRDIKPANIFLDQNMEAHLGDFGIARNL
... .  . |.|||.       |||||||||||.|     . | |||.. .|
ICRQILKGLLYYLHSHH-----IIHRDIKPANILL-----VKLCDFGVCGQL