Gene LRR25_b-2 (S.moellendorffii)

LRR25_b-2

Species: S.moellendorffii
Alias: LRR25_b-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LRR25

Sequence

Name Sequence Type Origin Length Description Download
LRR25_b-2.AA Protein None 673 None Fasta, JSON
LRR25_b-2.NA RNA None 2022 None Fasta, JSON
LRR25_b-2.kin_dom Protein Kinase Domain None 282 None Fasta, JSON

Protein domain

Protein domains of LRR25_b-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 LRR25_b-2.AA LRRNT_2 7-38 31 0.000374 16.39 Pfam 11-46 (46) Show / Hide 
Range on Protein: 7-38
Range on HMM: 11-46/46
Sequence Identity: 31% (12 aa)

LYGSWNS-PR----LSGWNSGP-GGDPCGESWQGVLCT
.  |.|. ..    || ||.   ..|.|   | || |.
FKSSLNDSDPHHGVLSSWNPSSSDSDCCS--WTGVTCD
LRR_1 LRR25_b-2.AA LRR_1 134-156 48 0.00019 19.94 Pfam 1-26 (26) Show / Hide 
Range on Protein: 134-156
Range on HMM: 1-26/26
Sequence Identity: 48% (13 aa)

NLNLLDVSF-N--QLTGSLPSS-FAGL
||  ||.|  |  .|||..|.| | .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_BAC LRR25_b-2.AA LRR_BAC 85-104 55 0.000229 21.75 SMART 1-20 (20) Show / Hide 
Range on Protein: 85-104
Range on HMM: 1-20/20
Sequence Identity: 55% (11 aa)

PPQLQEMYLSNNQLTGLPYS
||.|.... |||||| ||  
PPHLKWLNVSNNQLTELPEL
LRR_1 LRR25_b-2.AA LRR_1 110-132 37 0.000897 17.55 Pfam 1-26 (26) Show / Hide 
Range on Protein: 110-132
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

SLTKIDVSH-N--QLIGTIPDV-FQNF
.|...|.|. |  .| |.||.  | |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR25_b-2.AA LRR_1 87-108 37 0.002034 16.29 Pfam 1-26 (26) Show / Hide 
Range on Protein: 87-108
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

QLQEMYLSN-N--QLT-GLPYS-LKDL
.||. .||. |  .||  .| | .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR25_b-2.AA LRR_1 65-84 40 0.027674 12.27 Pfam 1-26 (26) Show / Hide 
Range on Protein: 65-84
Range on HMM: 1-26/26
Sequence Identity: 40% (11 aa)

NLKILDLSN-N--QLS-QAIPY---QL
||..||||. |  .|. . ||    .|
NLQHLDLSGCNCCNLTGH-IPPSCFNL
LRR_BAC LRR25_b-2.AA LRR_BAC 132-152 47 0.557785 3.16 SMART 1-20 (20) Show / Hide 
Range on Protein: 132-152
Range on HMM: 1-20/20
Sequence Identity: 47% (10 aa)

FSNLNLLDVSFNQLTGSLPSS
 ..|  |.||.|||| .||  
PPHLKWLNVSNNQLT-ELPEL
LRR_BAC LRR25_b-2.AA LRR_BAC 108-128 28 0.914587 1.52 SMART 1-20 (20) Show / Hide 
Range on Protein: 108-128
Range on HMM: 1-20/20
Sequence Identity: 28% (6 aa)

LWSLTKIDVSHNQLIGTIPDV
  .|....||.|| . . |. 
PPHLKWLNVSNNQ-LTELPEL
LRR_1 LRR25_b-2.AA LRR_1 158-179 18 2.711034 5.21 Pfam 1-26 (26) Show / Hide 
Range on Protein: 158-179
Range on HMM: 1-26/26
Sequence Identity: 18% (5 aa)

SISVMHVQN-N--KLSGDINV--LSDL
.. . .... |  .|.|.|    .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 LRR25_b-2.AA LRR_1 180-202 22 18.163132 2.28 Pfam 1-26 (26) Show / Hide 
Range on Protein: 180-202
Range on HMM: 1-26/26
Sequence Identity: 22% (6 aa)

PLADLNVEN-N--QFNGWVPSS-LRSI
 |  |.. . |  .. | .|.| . . 
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase LRR25_b-2.AA IRAK 369-580 34 3e-60 206.48 In-house 1-233 (317) Show / Hide 
Range on Protein: 369-580
Range on HMM: 1-233/317
Sequence Identity: 34% (81 aa)

FAQENLLGEGSLGRVYRAELQNGT-PLAVKKL--DASGSTVQTNEEFLA---FVSTIARLRHTNVTELVGYCAEHGQRLLVYEYFNRGTLHEMLHVLD-E
|...|..|||  | |||....| | . |||||   |. |. .  ..|..    . . .|.|| |. .| |||.| ..  |||.|   |.|.  |. .|  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

TS-KRLSWNQRVKIALGAARALEYLHEVCSP-AVVHRNFKSANILLDDDMSPHLTDCGLAALR------KNWQV----AAQMLGSFGYSAPEFAM--SGV
.. | ||| ||..|..|.|.....||.. .  .. |.. ||||||||... | ..| ||.  .      .   .    .    |.  | .|||    .| 
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

YTVKSDVYSFGVVMLELLTGRKPLDSSRARSEQ
.|.|.||||||.| ||.|||... .. |.. ..
LTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYY
Kinase LRR25_b-2.AA TKL 375-641 18 1e-56 194.76 In-house 1-364 (364) Show / Hide 
Range on Protein: 375-641
Range on HMM: 1-364/364
Sequence Identity: 18% (73 aa)

LGEGSLGRVYRAELQN---------GTPLAVKKLDASGSTVQTN-------------------------EEFLAFVSTIARLRHTNVTELVGYCAEHGQ-
.|.|. | ||......         |.. ||||.    .   |                          ...   .  . |||| |.  ..||| . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEYFNRGT-LHEMLHVLDETSKRLSWNQRVKIALGAARALEYLHEVCS-----PAVVHRNFKSANILLDDDMS-----------
              .|.||  .|. || ..           |.||...||..||...|||         |...||. ||.|||.|...            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNA

---PHLTDCGLAALR------KNWQVAAQ--------------MLGSFGYSAPEFAM----------------SGVYTVKSDVYSFGVVMLELLTGRKPL
   . ..| ||.         . .. . .                |.... |||  .                .. |. |.||||||.|. |.||...  
DWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR--

DSSRARSEQSLVRWATPQLHDIDAL---------SKMVDPALKGIYP------------AKSLSRFADVISSCVQPEPEFRPPMSEVVQSL
                 ... .. .         .. .|  |.   |               . .... .  | ...|| || ..|... |
--------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase LRR25_b-2.AA TKL-Unique 373-567 29 1.4e-42 147.82 In-house 3-224 (290) Show / Hide 
Range on Protein: 373-567
Range on HMM: 3-224/290
Sequence Identity: 29% (67 aa)

NLLGEGSLGRVYRAELQNGTPLAVKKLDA-SGSTVQTNEEFLAFVSTIARLR-HTNVTELVGYCA----EHGQRLLVYEYFNRGTLHEMLH---VLD---
|..|||. |.||...  .|.| |.|..   ..|  .  .||   |... .|. | |.. ..|||.      ... .| ||...|.|.. ||    .    
NKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

ETSKRLSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDD-----MSPHLTDCGLAALRKNW-QVAAQML---------GSFGYSAPEFAMS
. .. |...||||.|. .|....|||    | . ||. || |.|.| .     ..  . | ||. ....  .  . ..         ||| ..|||  ..
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLRM

--GVYTVKSDVYSFGVVMLELLTG
    |. ||||||||.|. |..|.
NFCQYSEKSDVYSFGIVLWEIATR
Kinase LRR25_b-2.AA MLK 369-641 21 6.3e-35 118.64 In-house 1-291 (291) Show / Hide 
Range on Protein: 369-641
Range on HMM: 1-291/291
Sequence Identity: 21% (67 aa)

FAQENLLGEGSLGRVYRAELQNGT----PLAVKKLD--ASGSTVQT---NEEFLAFVSTIARLRHTN----VTELVGYCAEHGQ-RLLVYEYFNRGTLHE
.  .  .|.|| | |.... .| .     .|||. .  .  . ..|    ..|  ..   ..|.| |    . ...| |.....  ..| ||   | |..
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

MLHVLDETSK----------RLSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDD------DMSPHLTDCGLAA-LRKNWQVAAQMLGSFGY
 ||  .  .           . .  . ...||  ||...|||.   ....||  || |||.|.      ..    .| |..  . .. .    . |.. .
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTNMMSNAGTYAW

SAPEF---AMSGVYTVKSDVYSFGVVMLELLTGRKPLDSSRARSEQSLVRWATPQLHDIDALSKMVDPALKGIY---PAKSLSRFADVISSCVQPEPEFR
 |||    . .. |. |.||.|.|||. |.||.. | .                   ..|..      |..|.    |     ...  .. | ...|. |
MAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVPYK------------------QHYDPMAIAWWVAYNGLRPPIPSTCPEHWKKLMKQCWNQDPHKR

PPMSEVVQSL
| ....|| |
PSFRQIVQHL
Kinase LRR25_b-2.AA Pkinase 369-584 22 1.2e-32 116.58 Pfam 1-228 (293) Show / Hide 
Range on Protein: 369-584
Range on HMM: 1-228/293
Sequence Identity: 22% (52 aa)

FAQENLLGEGSLGRVYRAELQNG-TPLAVKKLDASGSTVQTNEEFLA--FVSTIARLRHTNVTELVGYCAEHGQRLLVYEYFNRG----TLHEMLHVLDE
.  .  .|.|| |.||..  ..     |||... ..   . ... .    ..  .||.| |. .| ... ...   .| || . |     |......  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYIST--W

TSKRL--SWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDDMSP----HLTDCGLAAL--RKNWQVAAQMLGSFGYSAPEFAM-SGVYTVKS
 ....  |...  ....  .|.|||.|.     ..||  |..|||.|... .    ...| |||..    | . .    |. .| |||  . .  |. |.
RHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKV

DVYSFGVVMLELLTGRKPLDSS----RARSEQSLVR
|..|.|... |.|.|| | ...    . .... ...
DMWSCGCILYEMLCGRPPFPGHCWHDN-HDQMQMIC
Kinase LRR25_b-2.AA LRRK 369-572 24 3.9e-32 110.98 In-house 1-284 (351) Show / Hide 
Range on Protein: 369-572
Range on HMM: 1-284/351
Sequence Identity: 24% (72 aa)

FAQENLLGEGSLG-RVYRAELQN---------------------------GTPLAVKKLDASGSTVQTN-----------------------------EE
.  |...|.|. | .||||....                           ... |.||..  . |. .                              . 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

FLAF---VSTIARLRHTNVTELVGYCAEHGQRLLVYEYFNRGTLHEMLHVLDETS----K-RLSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANI
|  |   |. . .|.| |.  |.|.| ..  . .| ||   |.|.. ||   ...    | ..||. . ||||  |...||||  ..| ..||. || ||
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS-HNPPIIHRDLKSPNI

LL---D---------DDMSPHLTDCGLAA----LRKNWQVAAQMLGSFGYSAPEFAMSG---VYTVKSDVYSFGVVMLELLTGR-KPLD
||   .         ...  .. | |.      ...   ||  ..| .|. |||    .   .|| |.|.||||... ||||..  | |
LLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMG--VAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD
Kinase LRR25_b-2.AA TK 369-570 15 4.3e-30 97.48 In-house 1-394 (486) Show / Hide 
Range on Protein: 369-570
Range on HMM: 1-394/486
Sequence Identity: 15% (63 aa)

FAQENLLGEGSLG---RVYRAELQNG--------------------------TPLAVKKLDA-SGSTVQTNEE-----------FLAFVSTIARLR----
   .. ||||  |   .||..|....                          || ||| | . .... .  ..           ||.... .. ..    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HTNVTELVGYCAEH------------GQRLLVYEYFNRGT----LHEMLHVLDETSKR-----------------------------------------
 | |.  |.|.| ..            .  ..| || . |     |.. |.  ... .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------LSWNQRVKIALGAARALEYLHEV-CSPA---VVHRNFKSANILLDDDMS-----------PHLTDCGLA
                               |.  |.. ... .|...||||.  |.     .|||.    |.|.....              ..| ||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

----ALRKNWQVAAQMLGSFGY-----------------------------------------SAPEFAMSGV---------YTVKSDVYSFGVVMLELL
               .|    |                                          |||  ...|         .| ||||.||||.| |..
RQGSG----------VLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIF

T-GRKP
| |..|
TYGQEP
Kinase LRR25_b-2.AA Dicty4 369-570 31 1.4e-27 89.15 In-house 1-216 (277) Show / Hide 
Range on Protein: 369-570
Range on HMM: 1-216/277
Sequence Identity: 31% (69 aa)

FAQENLLGEGSLGRVYRAELQNGTPLAVKKL--DASGSTVQTNEEFLAFVSTIARLRHTNVTELVGYCA----EHGQRLLVYEYFNRGTLHEMLHV---L
 . |...|.||.| ||..    |.  |||||  .  ..   . .||.. |.  . .|| |.  . |.|     . |  . | ||  .|.|.. ||     
INIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE

DETSKRLSWNQRVK---IALGAARALEYLHEVCSPAVVHRNFKSANILLDDDMSPHLTDCGLAALRKNWQVAAQ----MLGSFGYSAPEFAMSGVYTVKS
   |. |.|  . .   .|. ||| . .||. | | ..||  ||.|.| |...    .| ||... |      .    . |. .. |||  |.  |. |.
QQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSFGVVMLELLTGRKP
|||||| |  |.||.  |
DVYSFGIVLWEILTRQEP
Kinase LRR25_b-2.AA RAF 369-570 26 2.5e-27 85.41 In-house 1-220 (282) Show / Hide 
Range on Protein: 369-570
Range on HMM: 1-220/282
Sequence Identity: 26% (60 aa)

FAQENLLGEGSLGRVYRAELQNGTPLAVKKLDASGSTVQTNEE---FLAFVSTIARLRHTNVTELVGYCAEHG--QRLLVYEYFNRGTLHEMLHVLDETS
.   .  |.|| | |||..     . |||.|  .  | .       |   |.   . || |.    ||  .        | ...   .|   .||  || 
VMVMTRIGSGSFGTVYRGHWH--GDVAVKMLNVNDPTPEQMQADVFFKNEVAVYKKTRHCNILLFMGYMSKPQTNTYAIVTQWCEHSSLYHHIHVQ-ETR

KRLSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDDMSPHLTDCGLAALRKNWQ-----VAAQMLGSFGYSAPEFAM--------------
...  .. . |..  . ...|||      ..||  || ||.|..||.   .| ||. ... |       . |  ..  . ||| .               
EKFDMHWLIDISRQVCQGMDYLHAK---NIIHRDLKSNNIFLHEDMTVKIGDFGLMTVKTRWSPRGNQQFEQPTHWILWMAPEVIRNLMIDWRGDVLMQD

SGVYTVKSDVYSFGVVMLELLTGRKP
   |. .|||||||.|| ||.|.. |
ENPYSFQSDVYSFGIVMYELMTRHMP
Kinase LRR25_b-2.AA TKL-ciliate2 369-564 27 7.9e-27 86.13 In-house 1-211 (273) Show / Hide 
Range on Protein: 369-564
Range on HMM: 1-211/273
Sequence Identity: 27% (60 aa)

FAQENLLGEGSLGRVYRAELQNGTPLAVKKLDASGSTVQTNEEFLAFVSTIARLRHTNVTELVGYCAEHGQRLLVYEYFNRGTLHEMLHVLDETSKRLSW
   .| . ||  | .|.|     .  ||||        |.  .|.     .  ||| |.   .| | .     .. ||  || |  .|    . . ||.|
LEIQNKITEGGYGIIYKAKWREIV-VAVKKFKMDHDNQQQIRDFVNECHAMEALRHPNIVMFLGACTKIPNFCIIMEYCQRGSLWSLLQ---NQDVRLTW

NQRVKIALGAARALEYLHEVCSPAVVHRNFK--------------------SANILLDDDMSPHLTDCGLAALRKNWQVAAQMLGSFGYSAPEFAMSGVY
  | .||| .||   |||    | ..||  |                    | |.|.|| .   ||| |    . .       .| . . |||   . .|
EDRRRIALDIARGVHYLH-SSNPPIIHRDLKRQIKHKEKNLINIITLIKINSLNVLVDDNFRCKLTDFGWTRVKPQDNYMTNKIGTYQWMAPEVIKAFYY

TVKSDVYSFGVVMLEL
| | ||.|..... |.
TEKADVFSYSIILWEI
Kinase LRR25_b-2.AA S_TKc 369-648 20 4.6e-26 93.84 SMART 1-231 (231) Show / Hide 
Range on Protein: 369-648
Range on HMM: 1-231/231
Sequence Identity: 20% (60 aa)

FAQENLLGEGSLGRVYRAELQN-GTPLAVKKLDASGSTVQTNEEFLAFVSTIARLRHTNVTELVGYCAEHGQRLLVYEYFNR--GTLHEMLHVLDETSKR
.   ...|.|. |.||..   . |   |.|...         | ..  ..   . .| |.  | ... . .   .| || .   |.|.....      .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

--LSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDDMSPHLTDCGLAALRKNWQVAAQMLGSFGYSAPEFAMSGVYTV-KSDVYSFGVVML
  ..  .  ...   ..||||.|.     ..||  | .|||||.     ..| |||..         . |.  | |||      |.  |.|..|.|... 
FPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILY

ELLTGRKPLDSSRARSEQSLVRWATPQLHDIDALSKMVDPALKGIYPAKSLSRFADVISSCVQPEPEFRPPMSEVVQ--SLVRLMQRA
|.|.|. | .      .| . .                             . . | |. | | .|| ||   |. |  .......  
EMLCGYPPFP-----QMQMMFKKIG-------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase LRR25_b-2.AA Dicty4-Unclassified 372-570 25 1.4e-24 81.07 In-house 4-207 (263) Show / Hide 
Range on Protein: 372-570
Range on HMM: 4-207/263
Sequence Identity: 25% (53 aa)

ENLLGEGSLGRVYRAELQNGTPLAVKKLDASGSTVQ--TNEEFLAFVSTIARLRHTNVTELVGYCAEH----GQRLLVYEYFNRGTLHEMLH-VLDETSK
   .|.| . .|..     |   ||||.            ..|.. |     . | |   . |||            | |   .|.| |. |    |  .
DQFIGKGHFSKVHKGNWK-GKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQ

RLSWNQ--RVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDDMSPHLTDCGLAALRKNWQVAAQMLGSFGYSAPEFAMSGVYTVKSDVYSFGVVML
 .. .    .|.|.  |. . .|| .    ..||  ||.|||.| .      | |..    . .      |     .||  |   |. ||||||..... 
PIKLDDTLIIKYAFDIAQGMQHLHTR---NFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLY

ELLTGRKP
||.||  |
ELATGDEP
Kinase LRR25_b-2.AA Pkinase_Tyr 369-509 24 2.4e-18 62.73 Pfam 1-148 (270) Show / Hide 
Range on Protein: 369-509
Range on HMM: 1-148/270
Sequence Identity: 24% (37 aa)

FAQENLLGEGSLGRVYRAELQ-----NGTPLAVKKLDASGSTVQT--NEEFLAFVSTIARL-RHTNVTELVGYCA-EHGQ--RLLVYEYFNRGTLHEMLH
      ||||. |.||....      ...| |||.|   |.. .    |.|.. ...   | .| |.  |.| |  . ..   ..| ||   | |.. |.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

VLDETSKRLSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDDM
   |  ..|.  . .....  |...|||..      .||     |.|.....
KHREDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENN
Kinase LRR25_b-2.AA TyrKc 369-641 20 1.5e-16 44.9 SMART 1-280 (280) Show / Hide 
Range on Protein: 369-641
Range on HMM: 1-280/280
Sequence Identity: 20% (62 aa)

FAQENLLGEGSLGRVYRAELQNGTPLAVKKLDASGSTVQTNEEFLAFVSTIARL--RHTNVTELVGYCAEH-------GQRLLVYEYFNRGTLHEMLHVL
   .  ||||  |.||....   .. |||.| ..       |.|.   .   .|  .| |.  |.|.| ..       .. ..| ||   | |.. |.  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

DETSKRLSWNQRVKIALGAARALEYLHEVCSPAVVHRNFKSANILLDDDMSPHLTDCGLA-ALRKN--------WQVA-----AQMLGSFGYSAPEFAMS
 ..   |.. . ..... .|.  ||||.     ..||     |.|....     .| ||. ..             ..     . ..      |||  . 
RPK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

GVYTVKSDVYSFGVVMLELLTGRKPLDSSRARSEQSLVRWATPQLHDIDALSKMVDPALKGIYPA--------KSLSRFADVISSCVQPEPEFRPPMSEV
|..| ||||.||||.| |..|  ..  .  .             . ..... .  .     . |          .   .  ....| . .|| || .||.
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ----------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQ-IMKQCWHEDPEDRPTFSEI

VQSL
.. .
HECF
Kinase LRR25_b-2.AA Pkinase_Tyr 539-570 54 6e-09 30.94 Pfam 182-214 (270) Show / Hide 
Range on Protein: 539-570
Range on HMM: 182-214/270
Sequence Identity: 54% (18 aa)

APEFAMSGVYTVKSDVYSFGVVMLELLT-GRKP
|||  . |..|.||||.||||.| |..| |..|
APECINYGKFTTKSDVWSFGVLMWEIFTYGEQP
Kinase LRR25_b-2.AA TK 616-641 30 4.4e-05 12.15 In-house 461-486 (486) Show / Hide 
Range on Protein: 616-641
Range on HMM: 461-486/486
Sequence Identity: 30% (8 aa)

FADVISSCVQPEPEFRPPMSEVVQSL
..|.. .| ...|| || .|.... |
YYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase LRR25_b-2.AA Pkinase_Tyr 618-641 37 0.003933 11.23 Pfam 247-270 (270) Show / Hide 
Range on Protein: 618-641
Range on HMM: 247-270/270
Sequence Identity: 37% (9 aa)

DVISSCVQPEPEFRPPMSEVVQSL
|.. .| ...|| || .||... |
DLMKQCWHYDPEDRPTFSEIHEQL
Kinase LRR25_b-2.AA LRRK 615-643 34 0.013384 5.0 In-house 323-351 (351) Show / Hide 
Range on Protein: 615-643
Range on HMM: 323-351/351
Sequence Identity: 34% (10 aa)

RFADVISSCVQPEPEFRPPMSEVVQSLVR
.. | | .| | .|. || .|..|. |  
MYQDLIQHCWQHDPKKRPHFSQIVKRLSQ
Kinase LRR25_b-2.AA TKL-ciliate2 598-642 24 0.026819 2.81 In-house 229-273 (273) Show / Hide 
Range on Protein: 598-642
Range on HMM: 229-273/273
Sequence Identity: 24% (11 aa)

KMVDPALKGIYPAKSLSRFADVISSCVQPEPEFRPPMSEVVQSLV
|..   |.   |     .|||..  | . . ..|| . |... | 
KVMCNNLRPTIPKNCPPQFADLMQRCWDNNQNLRPSFNEIIKELE
Kinase LRR25_b-2.AA Dicty4-Unclassified 620-641 36 0.048781 2.73 In-house 242-263 (263) Show / Hide 
Range on Protein: 620-641
Range on HMM: 242-263/263
Sequence Identity: 36% (8 aa)

ISSCVQPEPEFRPPMSEVVQSL
|  |   .|  || | ...| |
IKWCWHNDPNKRPTMNQIIQYL
Kinase LRR25_b-2.AA IRAK 631-641 45 0.203581 0.99 In-house 307-317 (317) Show / Hide 
Range on Protein: 631-641
Range on HMM: 307-317/317
Sequence Identity: 45% (5 aa)

RPPMSEVVQSL
|..| .|.|.|
RCDMAWVMQQL
Kinase LRR25_b-2.AA Dicty4 609-643 24 0.217805 0.59 In-house 241-277 (277) Show / Hide 
Range on Protein: 609-643
Range on HMM: 241-277/277
Sequence Identity: 24% (9 aa)

PAKSLSRFADVISSCVQPEPEFRPPMSEVVQS--LVR
|.  . .... |  |  ..|. || ..|..|   |  
PDWCPPSWKHLIQWCWDHDPQHRPSFEEIIQRRILEH
Kinase LRR25_b-2.AA TKL-Unique 615-641 29 0.333066 0.22 In-house 264-290 (290) Show / Hide 
Range on Protein: 615-641
Range on HMM: 264-290/290
Sequence Identity: 29% (8 aa)

RFADVISSCVQPEPEFRPPMSEVVQSL
.. | |  |  ..|. ||  .|.. .|
EYRDLIQQCWHHDPSQRPSFDEIIHRL