Gene LLEC_b (S.moellendorffii)

LLEC_b

Species: S.moellendorffii
Alias: LLEC_b
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: LLEC

Sequence

Name Sequence Type Origin Length Description Download
LLEC_b.AA Protein None 688 None Fasta, JSON
LLEC_b.NA RNA None 2067 None Fasta, JSON
LLEC_b.kin_dom Protein Kinase Domain None 216 None Fasta, JSON

Protein domain

Protein domains of LLEC_b.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Lectin_legB LLEC_b.AA Lectin_legB 17-252 36 2.8e-78 271.17 Pfam 1-268 (268) Show / Hide 
Range on Protein: 17-252
Range on HMM: 1-268/268
Sequence Identity: 36% (99 aa)

ESADILLQEFQQGS------MSLLGDAFL-RNGSIELT-KDSSGG-----LSSGRALFPSPIRL---VDRASNATASFNTSFTFSITNT--DAVHFGDGL
|. . .   |....        | ||| . .|| ..|| ......      | |.|..|.||..    |..... ||| |||.|.|.|.  .  . |.|.
ETVSFNYNGFTSNQCPSWSNLTLQGDATVHPNGALQLTPNVTNNPPPQPTNSMGHAFYPKPIHFWEDWDSSTGKVASFSTSFVFAIYNIPSYNTNGGHGM

AFIFAPSNTT--QGG-PGGWLGFLSASAPAGRPPPPTTQHSLAVEFDTFLNVEFMDPND--NHVGVDVDSMVSLEFADAG--------SERVELKS-GRP
||..|||.|    |. .|..|| |  .  .|..|     |..|||||||.|.|| |..|  ||||.|| |..|   ..||        . .. |.| |.|
AFFIAPSDTQNPPGASSGQYLG-LFNPTNNGDNP---SNHFVAVEFDTFQNPEFNDWDDNYNHVGIDVNSIRSVKSEPAGYYDDDDGRFVNWDLNSYGKP

ITAWIQYDSGRQEMEVSLSYN----AEQMPQKRLLSLSVNLYAVLDEYMFVGFSAAT-GGNIELHSLHSWQFS
...|| ||. .  . |.|.|.    |  .|.. ||| ||.| .|| ..|.|||||.| |.  |.| ..|| ||
MQVWIDYDGSSKQLNVTLAYPWTNMA-FKPKRPLLSWSVDLSQVLPDWMYVGFSASTGGNYTESHYILSWSFS
Kinase LLEC_b.AA TKL 364-575 21 2.5e-53 183.5 In-house 1-288 (364) Show / Hide 
Range on Protein: 364-575
Range on HMM: 1-288/364
Sequence Identity: 21% (68 aa)

LGYGAFGTVYKGRLRLLPVDMKSEAPTSDEIVE----VEVAVKRANR--GSKHGR-------------------------EEFMSELSIIGCLRHRNLVQ
.| |.||.||||..|  ..  .                .||||. ..   ... .                         ...  |. ..  ||| |.||
IGSGGFGEVYKGKWRGWGG-KC----------PSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQ

LQG---------WCRE----KNELLLVYDFMPNGS-LDKLLFDKSASSSALKWSVRFKVVVGIGSALAYLHSEW-----EQQVVHRDVKASNIMLDANLN
. |         .| .    ...| .|....|.|| |. |.           |..|.. . .| ....||||..       ...||| | .||..| |..
FMGYCCCPPCGCVCMHPVGPWGQLCIVMEYCPGGSLLHYLH-----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWT

--------------ARLGDFGLARLMEHDSSPETTI------------------TAGTVGYLAPEYL----------------HTGKATDKTDVFSFGIV
              . ..||||.| |..... . |                     || ...||| |                . .... |.||.|||||
NVSNYMYNPNADWCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIV

ALEVASGRRP
  |.....||
LWEILTRCRP
Kinase LLEC_b.AA IRAK 393-579 31 7.2e-48 165.34 In-house 19-227 (317) Show / Hide 
Range on Protein: 393-579
Range on HMM: 19-227/317
Sequence Identity: 31% (66 aa)

EIVEVE--VAVK--RANRGSKHG--REEFMS---ELSIIGCLRHRNLVQLQGWCREKNELLLVYDFMPNGSL-DKLLFDKSASS-SALKWSVRFKVVVGI
... ..  .|||  .... .. .  ...| .   || .   .|| |.| | | | |  .. |||..|||||| | |   . . .  .| |  |...  |.
QWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQCPPKPLSWHQRCSICWGT

GSALAYLHSEW-EQQVVHRDVKASNIMLDANLNARLGDFGLAR------LMEHDSS--PETTITAGTVGYLAPEYLH--TGKATDKTDVFSFGIVALEVA
. .. .||.      . |.|.| .|| ||..... ..||||.|       .|. ..   .| .. ||  |..||..   .|. | ||||.||||| |||.
ACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQLTKKTDVYSFGIVLLEVL

SGRRPITEE
.|.|. . .
TGCRAVYDD
Kinase LLEC_b.AA TK 360-575 18 3.2e-40 132.01 In-house 3-394 (486) Show / Hide 
Range on Protein: 360-575
Range on HMM: 3-394/486
Sequence Identity: 18% (72 aa)

FSQVLGYGAFG---TVYKGRLRLLPVDMKSEAPTSDEIV-----------EVEVAVKRANRGSKHGREEFMS--------------ELSIIGCLR-----
. ..|| |.||   .||||..| .. .  ...| ... |           ...||||    |. .  |||.               |....  ..     
LGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMT-VTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGH

HRNLVQLQGWCREK------------NELLLVYDFMPNGS----LDKLLFDKSASSSA------------------------------------------
| |.|.| | | ..              ...|  .||.|.    |.. | ...   .                                           
HPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYD

------------------------------LKWSVRFKVVVGIGSALAYLHSE---WEQQVVHRDVKASNIMLDANLN-----------ARLGDFG----
                              |    .    . | ....||||     .|..||||. | |.... |..           ....|||    
DDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

----LARLMEHDSSPETTITAGTVG-------------------------YLAPEYLH---------TGKATDKTDVFSFGIVALEVAS-GRRP
    ||| ...|.   .. . || .                         ..||| |          .|| | |.||.|||..  |. . |. |
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase LLEC_b.AA Pkinase 360-573 23 1.9e-39 140.54 Pfam 3-209 (293) Show / Hide 
Range on Protein: 360-573
Range on HMM: 3-209/293
Sequence Identity: 23% (54 aa)

FSQVLGYGAFGTVYKGRLRLLP--VDMKSEAPTSDEIVEVEVAVKRANRGSKHGREEFMSELSIIGCLRHRNLVQLQGWCREKNELLLVYDFMPNG----
. ...| |.||.|||.. .  .  | .|     ...  . . ....             ||..|   |.| | |.| .|...|... .| .....|    
IGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-------------SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVM

SLDKLLFDKSASSSAL--KWSVRFKVVVGIGSALAYLHSEWEQQVVHRDVKASNIMLDANLNA----RLGDFGLARLMEHDSSPETTITAGTVGYLAPEY
.|  ..     .. ..   . .  ...  | ..|.|.||.    ..|||.| .||..| | .     ...|||||..... ... .|  .|| .|.||| 
DLFDYIST--WRHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEV

LH-TGKATDKTDVFSFGIVALEVASGR
.    . . | |..|.|..  |...||
IRGGQYYGPKVDMWSCGCILYEMLCGR
Kinase LLEC_b.AA Pkinase_Tyr 360-565 30 6.9e-37 125.55 Pfam 3-203 (270) Show / Hide 
Range on Protein: 360-565
Range on HMM: 3-203/270
Sequence Identity: 30% (66 aa)

FSQVLGYGAFGTVYKGRLRLLPVDMKSEAPTSDEIVEVEVAVKRANRGSKHG---REEFMSELSIIGCL-RHRNLVQLQGWCR-EKNE--LLLVYDFMPN
| ..|| ||||.||||...            ...  ...||||  . |. |    ||.||.|..|   | .| |.|.| | |  ..    ...|  .||.
FGKKLGEGAFGEVYKGTWKG-----------DPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPH

GSLDKLLFDKSASSSALKWSVRFKVVVGIGSALAYLHSEWEQQVVHRDVKASNIMLDANLNARLGDFGLARLM-EHDSS-PETTITAGTVGYLAPEYLHT
|.|.. | ... .  .|. .   .  . | ....||.|   .. .|||. | |.... |. .. .||||||.. . |     .. .   .  .||| ...
GDLLDYLRKHREDKQPLTMKDLLQMCWQIAKGMEYLES---KNCIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINY

GKATDKTDVFSFGIV
|| | |.|| |||..
GKFTTKSDVWSFGVL
Kinase LLEC_b.AA LRRK 358-565 23 1.4e-33 116.19 In-house 1-271 (351) Show / Hide 
Range on Protein: 358-565
Range on HMM: 1-271/351
Sequence Identity: 23% (67 aa)

KGFSQVLGYGAFG-TVYKGRLR-------------LLPVDMKSEAPTSDEIVEVEVAVKRANRG----------------------------------SK
  . . .| |.|| .||....|             |.|. | . |  |.   . .||.|  ||.                                  . 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPY-MYQGARNSYDMCQ-WVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCC

HGREEFMSELSIIGCLRHRNLVQLQGWCREKNELLLVYDFMPNGSLDKLLFDKSASS-----SALKWSVRFKVVVGIGSALAYLHSEWEQQ--VVHRDVK
.   ||  |..|.  |.| |.|.| | |   . | .| ...|.|.|...|..|. ..       ..|... |... | ....||||   .   ..||| |
RAFREFRHEVWIMSHLNHPNIVSLKGFCI--HPLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHS---HNPPIIHRDLK

ASNIML---D---------ANLNARLGDFGLARLMEHDSSPE--TTITAGTVGYLAPEYLHTG---KATDKTDVFSFGIV
  || |   .         |. .| ..|||. | |   . ..  .    |. |..||| .  .     |.|.|..|||..
SPNILLWSSPQNHSPNYPNAHVCAKIADFGISR-MF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMI
S_TKc LLEC_b.AA S_TKc 358-661 22 7.6e-33 116.36 SMART 1-231 (231) Show / Hide 
Range on Protein: 358-661
Range on HMM: 1-231/231
Sequence Identity: 22% (69 aa)

KGFSQVLGYGAFGTVYKGRLRLLPVDMKSEAPTSDEIVEVEVAVKRANRGSKHGREEFMSELSIIGCLRHRNLVQLQGWCREKNELLLVYDFMPN--GSL
  . ...| ||||.|||.| .                   .||.|. .       | ...|..|    .| |.|.| ..... ..| .| .....  |.|
YEILRKIGKGAFGKVYKCRHKK---------------TGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDL

DKLLFDKSA--SSSALKWSVRFKVVVGIGSALAYLHSEWEQQVVHRDVKASNIMLDANLNARLGDFGLARLMEHDSSPETTITAGTVGYLAPEYLHTGKA
 ... ..      . .   .  ...  | .||.|.||   ....|||.| .||.||   .  ..||||||..        |   ||  |.||| |   . 
FDYIKKRGRHGLRFPFPE-HARFYMYQICCALEYCHS---HGIIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GY

TD-KTDVFSFGIVALEVASGRRPITEEEDNVTEESSGSSSSSSRVLVDWAWGLHRNGKLLQAADPKLGVEFEQVEMLLLLQVGLLCCHPDPTSRPSMKQA
.  | |. |.|..  | ..|. |    ..... .  |                                     |.. ...    |.. ||. ||.  .|
GKCKCDWWSCGCILYEMLCGYPPFP--QMQMMFKKIG-----------------------------------SPEAKDFIR---KCLQKDPEKRPTA-EA

VQ----ILCGEMT
 |    | | .  
LQDEWDIKCHPWF
Kinase LLEC_b.AA MLK 358-565 24 1.3e-32 110.45 In-house 1-225 (291) Show / Hide 
Range on Protein: 358-565
Range on HMM: 1-225/291
Sequence Identity: 24% (59 aa)

KGFSQVLGYGAFGTVYKGRLRLLPVDMKSEAPTSDEIVEVEVAVKRAN---RGSKHG----REEFMSELSIIGCLRHRN----LVQLQGWCREK-NELLL
  |....| |.|| |.||| |              .||  .|||||..   . .|      ...|  |  .   |.|.|     .|. | | .  .....
IQFHEWIGSGSFGKVWKGRWRN------------KDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCI

VYDFMPNGSLDKLLFDKSASSS----------ALKWSVRFKVVVGIGSALAYLHSEWEQQVVHRDVKASNIMLDA------NLNARLGDFGLARLMEHDS
|  ....|||  .| ...  ..            . .. ..  . . ....||||.  ....||| | .||..|.      .....  |||..| . .  
VMEYCEGGSLYNVLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC

SPETTITAGTVGYLAPEYL---HTGKATDKTDVFSFGIV
    . .|||. . ||| .     .| . | ||.|.|.|
-TNMMSNAGTYAWMAPEVIQQFRCEKYSEKCDVWSWGVV
Kinase LLEC_b.AA TyrKc 360-656 22 1.5e-32 115.39 SMART 3-280 (280) Show / Hide 
Range on Protein: 360-656
Range on HMM: 3-280/280
Sequence Identity: 22% (77 aa)

FSQVLGYGAFGTVYKGRLRLLPVDMKSEAPTSDEIVEVEVAVKRANRGSKHGREEFMSELSIIGCL--RHRNLVQLQGWCREK-------NELLLVYDFM
. ..|| ||||.||||...                  ..||||  . ..   ||.||.|..|   |  .| |.|.| | |...         |..|  .|
LGKKLGEGAFGEVYKGTWK------------------IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYM

PNGSLDKLLFDKSASSSALKWSVRFKVVVGIGSALAYLHSEWEQQVVHRDVKASNIMLDANLNARLGDFGLARLMEHD-----SSPETTI-----TA--G
|.|.|.. | ..      |...   .  . | .  .||||    ...|||  | |.....|. .. .||||.|  ..|     |.   .      .    
PHGDLKDYLRKHRPK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTML

TVGYLAPEYLHTGKATDKTDVFSFGIVALEVAS-GRRPITE---------------EEDNVTEESSG----SSSSSSRVLVDWAWGLHRNGKLLQAADPK
 .  .||| . .|| | |.||.|||..  |. . |  |  .               .. .  .        |                            
PIRWMAPECINYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----------------------------

LGVEFEQVEMLLLLQVGLL-CCHPDPTSRPSMKQAVQIL
    |  |..   .    . |.| || .||.... ....
----F--VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase LLEC_b.AA Dicty4-Unclassified 398-575 30 5.3e-30 99.93 In-house 24-207 (263) Show / Hide 
Range on Protein: 398-575
Range on HMM: 24-207/263
Sequence Identity: 30% (57 aa)

EVAVKRANRGSKHGR----EEFMSELSIIGCLRHRNLVQLQGWCREK----NELLLVYDFMPNGSLDKLLF-DKSASSSALKWSV--RFKVVVGIGSALA
.||||  | ..   |    ..|  |  | | . | |||.. | |         .  |  ||. | |  .     |     .|       |.   |   ..
DVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQ

YLHSEWEQQVVHRDVKASNIMLDANLNARLGDFGLARLMEHDSSPETTITAGTVGYLAPEYLHTGKATDKTDVFSFGIVALEVASGRRP
.||.     ..|||.|.|||..| . |.. .|||..|  .      ||| |||.   .|| |     . | ||.|....  | | |  |
HLHT---RNFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFN-MTTI-AGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDEP
Kinase LLEC_b.AA TKL-Unique 398-575 26 1.9e-29 101.06 In-house 22-233 (290) Show / Hide 
Range on Protein: 398-575
Range on HMM: 22-233/290
Sequence Identity: 26% (56 aa)

EVAVKRANR---GSKHGREEFMSELSIIGCLR-HRNLVQLQGWCR----EKNELLLVYDFMPNGSLDKLLFD---KS---ASSSALKWSVRFKVVVGIGS
.||.|. .     |.  ..|| .|.... .|. | |.|.. |.|       ... .| ...| |||...| .    .   .... | ...| | .  | .
PVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNNNNNCKLNMQQRVKMAIDIAQ

ALAYLHSEWEQQVVHRDVKASNIMLDAN-----LNARLGDFGLARLMEHDSSPETTIT----------AGTVGYLAPEYLHT--GKATDKTDVFSFGIVA
.. |||..    . ||| | ||. .| |     .|... ||||...   ..  ..|..           |.  ..||| |     . . | ||.||||| 
GMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKIN--KMTNNEHKGTRNQTRCGSFRWMAPEVLRMNFCQYSEKSDVYSFGIVL

LEVASGRR------P
 | |.. .      |
WEIATRKITKTYKKP
Kinase LLEC_b.AA UTK 360-565 24 3.5e-29 97.0 In-house 3-229 (296) Show / Hide 
Range on Protein: 360-565
Range on HMM: 3-229/296
Sequence Identity: 24% (59 aa)

FSQVLGYGAFGTVYKGRLRLLPVDMKSEAPTSDEIVEVEVAVKRANRGSK--HGRE---EFMSELS---IIGCLR-HRNLVQLQGWCREKNELLLVYDFM
... || ||||.|.|.|..          . |.   |. |||| ......  . .|   .|| |     . .... |.|...|.| |     ...|. .|
LGRQLGQGAFGEVHKARFT----------QCSEHMYEMDVAVKVCQHHADAQQEPEPYPDFMEEARELQMMKQFHWHPNVLRLVGVCTQEEPWMIVTEYM

PNGSLDKLLFDKSA----SSSALKWSVRFKVVVGIGSALAYLHSEWEQQVVHRDVKASNIMLDAN-------LNARLGDFG---LARLME-------HDS
.||.|...| . .        .|.   | . .. | ....|||   ....||||. | |. ....       . ....|||   ..|..         ..
ENGDLRSYLRRHRPTPPACPHWLTLHQRLCMAWDIARGMQYLH---SCGFVHRDLAARNCLVHMHRMMWHCMMVCKIADFGRGGMSRRVNTFHFSNRYWE

SPETTIT-AGT--VGYLAPEYLHTG-KATDKTDVFSFGIV
|.. . . ..   .   ||| |  . . | |.||.|||.|
SYYYMAQHQDRWPIRWMAPEALTHHTRFTTKSDVWSFGVV
Kinase LLEC_b.AA STE 358-581 20 8.6e-28 95.28 In-house 1-273 (359) Show / Hide 
Range on Protein: 358-581
Range on HMM: 1-273/359
Sequence Identity: 20% (59 aa)

KGFSQVLGYGAFGTVYKGRLRLLP-VDMKSEAPTSDEIVEVEVAVKRANRGSK-----------------HGREEFMSELSIIGCLR--HRNLVQLQGWC
  . ...| ||||||||.. .  .  . |.   . ...  . .|.|. |  ..                   ..... |..|  ...  | | |.  | .
WEGIEKIGKGAFGTVYKAMNHKNCNIH-KTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCY

REK-------NELLLVYDFMPNGSLDKLLFDKSASSSALK----------WSVRFKVVVGIGSA-LAYLHSEWEQQVVHRDVKASNIMLDANLNARLGDF
  .       .|| ..  .|..||||...  |      |.           |.  .... |  . |.||||   ....|||.|..||.|     . | ||
FKEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHS---HHIIHRDIKPANILL-----VKLCDF

GLARLMEH---------------DSSPETTITAGTVGYLAPEYLHT------GKATDKTDVFSFGIVALEVASGRRPITEEED
|..  ...               ... ...  .||  . ||| .        .. . | |. |.|....| | |. |  .. .
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPPWHDMHP
Kinase LLEC_b.AA RIPK 398-575 25 2.5e-27 90.15 In-house 19-227 (290) Show / Hide 
Range on Protein: 398-575
Range on HMM: 19-227/290
Sequence Identity: 25% (55 aa)

EVAVKRANRGSK-------HGREEFMSELSIIGCLRHRNLVQLQGWCREKNE------LLLVYDFMPNGSLDKLLFDKSA-SSSALKWSVRFKVVVGIGS
....| .  . .         |..   |  .   ||... |.. | |....       . .|  .|.|||| ..|  |.      . |..|.  .. | .
DWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQHHPDPWPLRCRMIHEISC

ALAYLHSEWEQQ--VVHRDVKASNIMLDANLNARLGDFGLARLMEHDSSPE----------TTITA--GTVGYLAPEYLH--TGKA----TDKTDVFSFG
.  ||||   ..  . ||| | .|| .|.|... . |||||  |.  .|            ..     ||  |..|| .     |.    | | || ||.
GMCYLHS---MNPPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNKKPIKVVTPKYDVYSFA

IVALEVASGRRP
||  || ... |
IVMWEVLTQKHP
Kinase LLEC_b.AA TKL 638-656 36 4e-06 17.97 In-house 346-364 (364) Show / Hide 
Range on Protein: 638-656
Range on HMM: 346-364/364
Sequence Identity: 36% (7 aa)

CCHPDPTSRPSMKQAVQIL
|...||..|||... ...|
CWDHDPEKRPSFQEILKRL
Kinase LLEC_b.AA TK 636-656 38 3.3e-05 12.56 In-house 466-486 (486) Show / Hide 
Range on Protein: 636-656
Range on HMM: 466-486/486
Sequence Identity: 38% (8 aa)

LLCCHPDPTSRPSMKQAVQIL
. |.|.||  ||...| .. |
QQCWHYDPEDRPTFSQLHEQL
Kinase LLEC_b.AA MLK 638-656 52 7.1e-05 13.0 In-house 273-291 (291) Show / Hide 
Range on Protein: 638-656
Range on HMM: 273-291/291
Sequence Identity: 52% (10 aa)

CCHPDPTSRPSMKQAVQIL
| ..|| .|||..| ||.|
CWNQDPHKRPSFRQIVQHL
Kinase LLEC_b.AA Dicty4-Unclassified 638-656 52 0.000518 9.59 In-house 245-263 (263) Show / Hide 
Range on Protein: 638-656
Range on HMM: 245-263/263
Sequence Identity: 52% (10 aa)

CCHPDPTSRPSMKQAVQIL
| | ||  ||.| | .| |
CWHNDPNKRPTMNQIIQYL
Kinase LLEC_b.AA TKL-Unique 360-392 42 0.001115 9.06 In-house 1-33 (290) Show / Hide 
Range on Protein: 360-392
Range on HMM: 1-33/290
Sequence Identity: 42% (14 aa)

FSQVLGYGAFGTVYKGRLRLLPVDMKSEAPTSD
|. ..| |..|.||||  |  || .|...| .|
FWNKIGEGGYGQVYKGKWRGYPVAIKQFHPNED
Kinase LLEC_b.AA UTK 638-656 42 0.00122 8.33 In-house 278-296 (296) Show / Hide 
Range on Protein: 638-656
Range on HMM: 278-296/296
Sequence Identity: 42% (8 aa)

CCHPDPTSRPSMKQAVQIL
|.|.||  ||.... || .
CWHYDPQERPDFEDLVQQM
Kinase LLEC_b.AA Pkinase_Tyr 636-656 33 0.004661 10.98 Pfam 250-270 (270) Show / Hide 
Range on Protein: 636-656
Range on HMM: 250-270/270
Sequence Identity: 33% (7 aa)

LLCCHPDPTSRPSMKQAVQIL
..| |.||  ||.... ...|
KQCWHYDPEDRPTFSEIHEQL
Kinase LLEC_b.AA IRAK 360-378 38 0.006132 6.45 In-house 1-21 (317) Show / Hide 
Range on Protein: 360-378
Range on HMM: 1-21/317
Sequence Identity: 38% (8 aa)

FSQ--VLGYGAFGTVYKGRLR
|..  ..| |.||.||.|...
FHKDNRIGEGGFGCVYRGQWK
Kinase LLEC_b.AA LRRK 637-658 36 0.006867 6.04 In-house 330-351 (351) Show / Hide 
Range on Protein: 637-658
Range on HMM: 330-351/351
Sequence Identity: 36% (8 aa)

LCCHPDPTSRPSMKQAVQILCG
.| . ||..||.. | |..|  
HCWQHDPKKRPHFSQIVKRLSQ
Kinase LLEC_b.AA TKL-Unique 638-656 42 0.007817 6.04 In-house 272-290 (290) Show / Hide 
Range on Protein: 638-656
Range on HMM: 272-290/290
Sequence Identity: 42% (8 aa)

CCHPDPTSRPSMKQAVQIL
|.|.||. |||  . .  |
CWHHDPSQRPSFDEIIHRL
Kinase LLEC_b.AA RIPK 364-374 54 0.010136 5.06 In-house 1-11 (290) Show / Hide 
Range on Protein: 364-374
Range on HMM: 1-11/290
Sequence Identity: 54% (6 aa)

LGYGAFGTVYK
.| |.||.|.|
VGGGGFGEVFK
Kinase LLEC_b.AA Pkinase 638-656 33 0.139038 6.68 Pfam 273-293 (293) Show / Hide 
Range on Protein: 638-656
Range on HMM: 273-293/293
Sequence Identity: 33% (7 aa)

CCHPDPTSRPSMKQAVQI--L
|...||..||. .|..|   .
CLCKDPKKRPTAEQILQHPWF