Gene IRAKm_b-2 (S.moellendorffii)

IRAKm_b-2

Species: S.moellendorffii
Alias: IRAKm_b-2
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKm

Sequence

Name Sequence Type Origin Length Description Download
IRAKm_b-2.AA Protein None 848 None Fasta, JSON
IRAKm_b-2.NA RNA None 2547 None Fasta, JSON
IRAKm_b-2.kin_dom Protein Kinase Domain None 195 None Fasta, JSON

Protein domain

Protein domains of IRAKm_b-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin IRAKm_b-2.AA B_lectin 107-204 29 1.9e-20 71.87 Pfam 1-137 (137) Show / Hide 
Range on Protein: 107-204
Range on HMM: 1-137/137
Sequence Identity: 29% (40 aa)

TAAPVWIANRN---TPV-----SGNSMLAKT--GGRLQLLDAN-G-SV--AWSP------SE--SVAYIGIQNSGNLQLF-DES--ETPVWSS--FDRPW
   .|| |||.   .||     .||..|  .   | | |.|.. | ||   ||       |   . ..  .|.|||| |. |..   ...|.|  || | 
NQTVVWVANRDLTGNPVTDSSNNGNYTLTMQNRDGNLVLYDGGNGGSVRPVWSTNNNTSGSGSANNCRAQMQDSGNLVLYDDNNDSNNVLWQSNTFDHPT

SALMPNQKLVT------GQS----VVSNKNAS--DPS
  . |..|| .      ...     .| |...  |||
DTWLPGMKLGWDNNVTIYMNWIGYLTSWKSNTNYDPS
B_lectin IRAKm_b-2.AA B_lectin 65-178 22 8.2e-09 36.52 SMART 1-126 (126) Show / Hide 
Range on Protein: 65-178
Range on HMM: 1-126/126
Sequence Identity: 22% (29 aa)

DSPSSRPESLRSDDENLG--LAFLNFNGSNKYYLALMFGTRNSSTAAPVWIA--NRNTPVSG---NSMLAKT-GGRLQLLDANGSVAWSPSES----VAY
|.. |  ..| |..      | | .|...   ..   ..  . ..  .|| |  ||. ||..   .. |  .  | | ..|  ... || . .    .  
DNTLSSGQTLVSGNSLFEFYLGFFTFIMQ--WCNGIWYKNISNKQRTVVWVAQPNRDNPVHDGNNSCYLTMQSDGNLVIYD--NRPVWSSNTTRNNGNYV

IGIQNSGNLQLFDES----ETPVWSSFDRP
   | .||. ..|..    .  .|.||| |
AVLQDDGNFVIYDPDDNDSGNFIWQSFDHP
PAN_AP IRAKm_b-2.AA PAN_AP 376-453 15 0.000516 17.9 SMART 1-85 (85) Show / Hide 
Range on Protein: 376-453
Range on HMM: 1-85/85
Sequence Identity: 15% (14 aa)

RYETDFVTLAGASYFANTFNPP-----DRTGAAMQDCFEQCKSTCSCAAFFFDQALQNCFFVE--DVLGSLT------VDSNKTQQLFGFL
  ...|| . ....    |.|          . ...| ..|   ||| .| ..   ..| .    . ||. .         | .. ..  .
CCDDCFVRMPNMKL----FSPIVNWVDVI-VMSLEECMQKCLNNCSCRSFMYYN-TKGCHLWSWDSHLGDPRQFKRFMKFPNQGVDYYEKN
Kinase IRAKm_b-2.AA TKL 538-802 19 4.5e-64 219.19 In-house 1-364 (364) Show / Hide 
Range on Protein: 538-802
Range on HMM: 1-364/364
Sequence Identity: 19% (76 aa)

LGSGGCGTVYEGMLHN---------GMKLAVKKLSTQHGQ-----------------------------KEFVTEVSALGNISHINIVKLYGFCADASH-
.|||| |.|| | ...         |   ||||..... .                             .... |.  . ...| |||...|.| . .. 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYELMPNGSLDRWIFSDNKDKLDWKLRHSIALDTARGLAYLHEESR-----DSIIHLDIKPQNILLGDKFE--------------
              .|.|..|.|||   .         | .|...|||.|||..||| .         ||| |.|..|||. ....              
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWC

AKVADFGMAKLLMDRDQNG-----------------VVTGVRGTPGYLAPEWLLHS----------------TATKKCDVYSYGMVLLELIGGRKNLDCS
.|..||| .. .  . ..                      ..|||...||| |  .                ....||||||.|.|| |.. ...     
CKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-----

KMESPLS-WYFPAWAMS----EIRKGNTMQVVDPSVKD--------SADTRQAKNMIHIAFWCTQDDPAARPTMDAVVRML
    | .   .. . ..    |. ...      | ...        .  .   . |. .. .| . || .||... ..  |
----PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAKm_b-2.AA Pkinase 534-802 22 3.6e-52 184.42 Pfam 3-293 (293) Show / Hide 
Range on Protein: 534-802
Range on HMM: 3-293/293
Sequence Identity: 22% (71 aa)

FTKVLGSGGCGTVYEGMLHNGMK-LAVKKLSTQHGQKEFVT-------EVSALGNISHINIVKLYGFCADASHRLLVYELMPNG----SLDRWIFSDNKD
. ...|||. |.||... ..  |  |||... . ..|. .        |.. . ...| |||.||... | .|  .| |....|    .| ..|  ... 
IGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRHG

KL--DWKLRHSIALDTARGLAYLHEESRDSIIHLDIKPQNILLGDKFEA----KVADFGMAKLLMDRDQNGVVTGVRGTPGYLAPEWLL-HSTATKKCDV
..  ...   .... ..|||.|.|..   .||| |.||.|||. .. .     |..||| ||..     |.  |.. |||.|.|||... ..  ..|.|.
CFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVDM

YSYGMVLLELIGGRKNLDCSKMESPLSWYFPA---------WAMSEIRKGNTMQVVDPSVKDS------------ADTRQAKNMIHIAFWCTQDDPAARP
.|.| .| |.. ||           . ..  .         . . .|... ..   . .   |              ... ......  || . ||. ||
WSCGCILYEMLCGR-----------PPFP-GHCWHDNHDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTF-HNWSEECKDFIKWCLCKDPKKRP

TMDAVVRM--L
| . ..    .
TAEQILQHPWF
Kinase IRAKm_b-2.AA TKL-Unique 534-725 28 1.3e-46 161.14 In-house 1-222 (290) Show / Hide 
Range on Protein: 534-725
Range on HMM: 1-222/290
Sequence Identity: 28% (64 aa)

FTKVLGSGGCGTVYEGMLHNGMKLAVKKLST---QHGQ--KEFVTEVSALGNIS-HINIVKLYGFCA----DASHRLLVYELMPNGSLDRWIFS------
| ...|.||.|.|| |. ..| . |.|...    .. .  .||  ||. . ..  |.|||...|.|.    ..... .| | .| |||.  .        
FWNKIGEGGYGQVYKGK-WRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--DNKDKLDWKLRHSIALDTARGLAYLHEESRDSIIHLDIKPQNILLGDK-----FEAKVADFGMAKLLMDRDQNGVV-------TGVRGTPGYLAPEWL
   |. ||....| ..|.| |.|. ||| ..   |||.|.|..|.|.  .     . .|..||| .|..  .... .        ... |.. ..||| |
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

LH--STATKKCDVYSYGMVLLELI
    .. ..|.||||.|.|| |..
RMNFCQYSEKSDVYSFGIVLWEIA
Kinase IRAKm_b-2.AA Dicty4 534-724 32 7.3e-45 147.64 In-house 3-210 (277) Show / Hide 
Range on Protein: 534-724
Range on HMM: 3-210/277
Sequence Identity: 32% (68 aa)

FTKVLGSGGCGTVYEGMLHNGMKLAVKKL-STQHGQ-----KEFVTEVSALGNISHINIVKLYGFCA----DASHRLLVYELMPNGSLDRWIFS-----D
... .|.|..|.|| |    | . ||||| ... .      .||  ||. ...|.| ||....| |       .  . | |.|| |.| . . .      
IEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQ

NKDKLDWKLRHS---IALDTARGLAYLHE-ESRDSIIHLDIKPQNILLGDKFEAKVADFGMAKLLMDRDQNGV-VTGVRGTPGYLAPEWLLHSTATKKCD
 ..|||| |. .   .|.|.|||...||.  ..  |||.|.|. |.|  . . .||.||| ...     ...   ... |||.. ||| . |   . | |
QSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV--IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKAD

VYSYGMVLLEL
|||.|.|| |.
VYSFGIVLWEI
Kinase IRAKm_b-2.AA IRAK 534-729 36 3.1e-42 146.63 In-house 1-222 (317) Show / Hide 
Range on Protein: 534-729
Range on HMM: 1-222/317
Sequence Identity: 36% (81 aa)

FTK--VLGSGGCGTVYEGMLHNGM-KLAVK------KLSTQHGQKEFVT---EVSALGNISHINIVKLYGFCADASHRLLVYELMPNGSL-DRWIFSDNK
| |  ..|.|| |.|| | ..|     |||      ..|.    ..| .   |. ..  . | ||| |||.|.. .   |||..|||||| ||    |. 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

DK---LDWKLRHSIALDTARGLAYLHEES-RDSIIHLDIKPQNILLGDKFEAKVADFGMAKLL---MDRDQNGV----VTGVRGTPGYLAPEWLL--HST
.    | |  |.||.. ||.|. .||. .   .||| |||. |||| . |..| .|||..       .. .  .    .  ||||  |..|| .      
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

ATKKCDVYSYGMVLLELIGGRK
 ||| |||| | ||||.. |..
LTKKTDVYSFGIVLLEVLTGCR
Kinase IRAKm_b-2.AA MLK 532-725 28 8.7e-40 135.72 In-house 1-230 (291) Show / Hide 
Range on Protein: 532-725
Range on HMM: 1-230/291
Sequence Identity: 28% (66 aa)

KGFTKVLGSGGCGTVYEGMLHNGMK-----LAVKKLS--------TQHGQKEFVTEVSALGNISHIN----IVKLYGFCADA-SHRLLVYELMPNGSLDR
  | ...|||. | |. |  .| .      .|||.          |   |..| .|.  |  .|| |    |...|| |..  .| ..| | ...||| .
IQFHEWIGSGSFGKVWKGRWRN-KDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

WIFSD--------NKDK----LDWKLRHSIALDTARGLAYLHEESRDSIIHLDIKPQNILLGD------KFEAKVADFGMAKLLMDRDQNGVVTGVRGTP
 . .         ...|     |  .  ..||. |||..|||.. .. ||| |.|..|||. .      .  .|..||| .. . ....|   .. .||.
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTN--MMSNAGTY

GYLAPEWL---LHSTATKKCDVYSYGMVLLELI
 . ||| .    ... ..||||.|.|.|| |..
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEML
Kinase IRAKm_b-2.AA LRRK 532-725 25 5.2e-38 132.04 In-house 1-276 (351) Show / Hide 
Range on Protein: 532-725
Range on HMM: 1-276/351
Sequence Identity: 25% (72 aa)

KGFTKVLGSGGCG-TVYEGMLHN---------------------------GMKLAVKKLSTQ------------------------------------HG
  . . .|.|| | .|| . . .                           . . |.||. .                                     . 
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

QKEFVTEVSALGNISHINIVKLYGFCADASHRLLVYELMPNGSLDRWIFSDNKDK-------LDWKLRHSIALDTARGLAYLHEESRD-SIIHLDIKPQN
  ||  ||. . .  | |||.|.||| .  .. .| |..|.|.|.. ...  .|.       ..| |.. |||. |.|..|||  |.. .||| | |. |
FREFRHEVWIMSHLNHPNIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH--SHNPPIIHRDLKSPN

ILL-GDK-----------FEAKVADFGMAKLLMDRDQNGVVTGVRGTPGYLAPEWLL---HSTATKKCDVYSYGMVLLELI
||| . .             ||.||||    .   ...||. |. |.||..||| .     .. | | |.||.||.| ||.
ILLWSSPQNHSPNYPNAHVCAKIADFGISR-MFQCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELL
Kinase IRAKm_b-2.AA Dicty4-Unclassified 569-727 39 5.8e-37 124.1 In-house 43-204 (263) Show / Hide 
Range on Protein: 569-727
Range on HMM: 43-204/263
Sequence Identity: 39% (67 aa)

KEFVTEVSALGNISHINIVKLYGFCADA-SHR---LLVYELMPNGSLDRWIF-----SDNKDKLDWKLRHSIALDTARGLAYLHEESRDSIIHLDIKPQN
..|  ||  || |.| | ||.|| |    ||.     | |.|. | |   |       .   |||  |   .|.| |.|...||  .|. .|| |||  |
QDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLH--TRN-FIHRDIKSSN

ILLGDKFEAKVADFGMAKLLMDRDQNGVVTGVRGTPGYLAPEWLLHSTATKKCDVYSYGMVLLELIGG
||.   | .|.||||..      | |   | . |||   .|| | |   . | |||||.|.| ||. |
ILMDKHFNIKIADFGISRVI---DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATG
Kinase IRAKm_b-2.AA S_TKc 532-802 23 3.4e-36 127.5 SMART 1-231 (231) Show / Hide 
Range on Protein: 532-802
Range on HMM: 1-231/231
Sequence Identity: 23% (69 aa)

KGFTKVLGSGGCGTVYEGMLHN-GMKLAVKKLSTQHGQKEFVTEVSALGNISHINIVKLYGFCADASHRLLVYELMPN--GSLDRWIFSDNKDK----LD
  . ...|.|. |.|| .  .. | . |.|...     . .  |.. | .  | ||||||... | .|  .| |....  |.| . | . .. .    ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-----EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFPFP

WKLRHSIALDTARGLAYLHEESRDSIIHLDIKPQNILLGDKFEAKVADFGMAKLLMDRDQNGVVTGVRGTPGYLAPEWLLHSTATK-KCDVYSYGMVLLE
     ...  ....|.|.|.     ||| |.||.|||| .  . |..|||.|..|         | . ||| |.||| |     .| |||..| | .| |
E-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LIGGRKNLDCSKMESPLSWYFPAWAMSEIRKGNTMQVVDPSVKDSADTRQAKNMIHIAFWCTQDDPAARPTMDAVVR---------ML
.. |.   .               .| .. .                    . ....   | | ||. |||   . .          .
MLCGYPPFP------------QMQMMFKKIG-------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKm_b-2.AA Pkinase_Tyr 534-725 27 7.9e-34 115.2 Pfam 3-208 (270) Show / Hide 
Range on Protein: 534-725
Range on HMM: 3-208/270
Sequence Identity: 27% (59 aa)

FTKVLGSGGCGTVYEGMLH-----NGMKLAVKKL--STQHGQ---KEFVTEVSALGNI-SHINIVKLYGFCA-DASH--RLLVYELMPNGSLDRWIFSD-
| |.||.|  |.||.| ..     .... |||.|  .. | |   ..|  |.. . .. .| |||.||| |  .  .   ..| |.||.|.|.    .  
FGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR

-NKDKLDWKLRHSIALDTARGLAYLHEESRDSIIHLDIKPQNILLGDKFEAKVADFGMAKLLMDRDQNGVVTG------VRGTPGYLAPEWLLHSTATKK
 .|..|. |   ..... |.|..||..     .|| |.   |.|..... .|..|||.|..... |.  ....      .. .    ||| . ..  | |
EDKQPLTMKDLLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWM----APECINYGKFTTK

CDVYSYGMVLLELI
 ||.|.| .. |..
SDVWSFGVLMWEIF
Kinase IRAKm_b-2.AA STE 534-728 22 9.2e-33 113.05 In-house 1-265 (359) Show / Hide 
Range on Protein: 534-728
Range on HMM: 1-265/359
Sequence Identity: 22% (63 aa)

FTK--VLGSGGCGTVYEGMLHN----------------GMKLAVKKLSTQHG-------------------QKEFVTEVSALGNIS--HINIVKLYGFCA
...  ..|.|..|||| .| |.                |   |.|... ..                    ....  |.. . . .  | |||| || . 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

DA-------SHRLLVYELMPNGSLDRWIF---SDNK---------DKLDWKLRHSIALDTARG-LAYLHEESRDSIIHLDIKPQNILLGDKFEAKVADFG
.        ..  .. |.|..||||  |    . .|         .... ..   |. .. .| |.|||.     ||| ||||.||||     .| .|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

MAKLLMD--------------RDQNGVVTGVRGTPGYLAPEWLLH------STATKKCDVYSYGMVLLELIGGR
 .. | |               .. .  . . ||| . ||| ..       .  . |||..| | ...|.. |.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK
Kinase IRAKm_b-2.AA TK 534-724 15 1.4e-32 105.97 In-house 3-387 (486) Show / Hide 
Range on Protein: 534-724
Range on HMM: 3-387/486
Sequence Identity: 15% (61 aa)

FTKVLGSGGCG---TVYEGMLHNG--------------------------MKLAVKKLS--TQHGQKEFVT--------------EVSALGNIS-----H
. |.||.|  |   .||.|.....                          .. ||| |   . . |.||                |....   .     |
LGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLGHH

INIVKLYGFCADA------------SHRLLVYELMPNGS----LDRWIFSD-------------------------------------------------
 |||.||| | .              . ..| |.||.|.    |. .  .                                                  
PNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDYDD

-------------------------NKDKLDWKLRHSIALDTARGLAYLHEE----SRDSIIHLDIKPQNILLGDKFE-----------AKVADFGMAK-
                         .|..|. . .. .... |.|..|||.         ..| |.   |.|.|..             .|.||||... 
DLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSRQ

------LLMDRDQNGVVTGVRGTPG-------------------------YLAPEWLL---------HSTATKKCDVYSYGMVLLEL
        ...|.. .... .||..                         ..||| |.         . . | | ||.|.| .. |.
GSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEI
Kinase IRAKm_b-2.AA DRK 539-725 33 1.7e-31 103.96 In-house 8-196 (258) Show / Hide 
Range on Protein: 539-725
Range on HMM: 8-196/258
Sequence Identity: 33% (65 aa)

GSGGCGTVYEGMLHNGMKLAVKKLSTQHGQ-----KEFVTEVSALGNISHINIVKLYGFCADASHRLLVYELMPNGSLDRWIFSDNKDKLDWKLRHSIAL
| |..| |. |    | . |||.|           .||  |.  . .  | ||.   | |   .  . . | || ||| . |  | . ..|| |. ....
GRGNYGEVFRGTWR-GTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYN-ILHDESIEMDWPLMKQMMF

DTARGLAYLHEESRDSII-HLDIKPQNILLGDKFEAKVADFGMAK-LLMDRDQNGVVTGVRGTPGYLAPEWLLHSTATKKCDVYSYGMVLLELI
| |.|. |||  ... || | | |  | |  . .  |||||| .      ...    | . |||.  ||| |     | | ||||.. || |..
DCAKGMIYLH--CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMC-GTPCWTAPEVLRNQRYTEKADVYSFAIVLWECV
Kinase IRAKm_b-2.AA TyrKc 534-802 24 3.6e-26 94.2 SMART 3-280 (280) Show / Hide 
Range on Protein: 534-802
Range on HMM: 3-280/280
Sequence Identity: 24% (72 aa)

FTKVLGSGGCGTVYEGMLHNGMKLAVKKLSTQHGQKEFVTEVSALGNI--SHINIVKLYGFCADA-------SHRLLVYELMPNGSLDRWI-FSDNKDKL
. |.||.|  |.||.|..   .. |||.|   . ...|  | . . ..  .| |||.||| | .           ..| |.||.|.|.  .  . .|  |
LGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK--L

DWKLRHSIALDTARGLAYLHEESRDSIIHLDIKPQNILLGDKFEAKVADFGMAKLLMDR-------DQNGVVT--GVR--GTPGYLAPEWLLHSTATKKC
 .|  .|.... |.| .|||.     .|| |.   |.|.|... .|..|||... . |        |   . .  | .       .||| . ... | | 
CMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTTKS

DVYSYGMVLLELIGGRKNLDCSKMESPLSW-----YFPAWAMSEIRKGNTMQVVDP----SVKDSADTRQAKNMIHIAFWCTQDDPAARPTMDAVVRML
||.|.| .. |.        ..  ..| .        .. ..  ...|. |   .     |   .   .  . |  |  .| . ||. |||. .... .
DVWSFGVCMWEI--------FTYGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS---F--VCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase IRAKm_b-2.AA TK 784-802 36 7.9e-05 11.28 In-house 468-486 (486) Show / Hide 
Range on Protein: 784-802
Range on HMM: 468-486/486
Sequence Identity: 36% (7 aa)

CTQDDPAARPTMDAVVRML
| . ||. |||.......|
CWHYDPEDRPTFSQLHEQL
Kinase IRAKm_b-2.AA DRK 784-804 38 0.000106 11.89 In-house 238-258 (258) Show / Hide 
Range on Protein: 784-804
Range on HMM: 238-258/258
Sequence Identity: 38% (8 aa)

CTQDDPAARPTMDAVVRMLES
|   ||  ||.|. ..  ||.
CWNEDPQHRPSMQECLERLEA
Kinase IRAKm_b-2.AA Dicty4-Unclassified 783-802 45 0.000317 10.33 In-house 244-263 (263) Show / Hide 
Range on Protein: 783-802
Range on HMM: 244-263/263
Sequence Identity: 45% (9 aa)

WCTQDDPAARPTMDAVVRML
||  .||  ||||. ..  |
WCWHNDPNKRPTMNQIIQYL
Kinase IRAKm_b-2.AA LRRK 783-804 36 0.002292 7.75 In-house 330-351 (351) Show / Hide 
Range on Protein: 783-804
Range on HMM: 330-351/351
Sequence Identity: 36% (8 aa)

WCTQDDPAARPTMDAVVRMLES
.| | ||  ||..  .|  |..
HCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAKm_b-2.AA MLK 784-802 36 0.03295 3.62 In-house 273-291 (291) Show / Hide 
Range on Protein: 784-802
Range on HMM: 273-291/291
Sequence Identity: 36% (7 aa)

CTQDDPAARPTMDAVVRML
| ..||. ||... .|  |
CWNQDPHKRPSFRQIVQHL
Kinase IRAKm_b-2.AA Dicty4 783-804 33 0.096902 1.78 In-house 254-277 (277) Show / Hide 
Range on Protein: 783-804
Range on HMM: 254-277/277
Sequence Identity: 33% (8 aa)

WCTQDDPAARPTMDAVVRM--LES
||   ||  ||..  ..    ||.
WCWDHDPQHRPSFEEIIQRRILEH
Kinase IRAKm_b-2.AA Pkinase_Tyr 788-802 40 0.113063 6.29 Pfam 256-270 (270) Show / Hide 
Range on Protein: 788-802
Range on HMM: 256-270/270
Sequence Identity: 40% (6 aa)

DPAARPTMDAVVRML
||. |||. .....|
DPEDRPTFSEIHEQL
Kinase IRAKm_b-2.AA TKL-Unique 784-802 36 0.335219 0.21 In-house 272-290 (290) Show / Hide 
Range on Protein: 784-802
Range on HMM: 272-290/290
Sequence Identity: 36% (7 aa)

CTQDDPAARPTMDAVVRML
|  .||  ||. | ..  |
CWHHDPSQRPSFDEIIHRL