IRAKm_h

Species: S.moellendorffii
Alias: IRAKm_h
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKm

Sequence

Name Sequence Type Origin Length Description Download
IRAKm_h.AA Protein None 452 None Fasta, JSON
IRAKm_h.NA RNA None 1359 None Fasta, JSON
IRAKm_h.kin_dom Protein Kinase Domain None 198 None Fasta, JSON

Protein domain

Protein domains of IRAKm_h.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAKm_h.AA TKL 142-412 20 2.9e-61 209.87 In-house 1-364 (364) Show / Hide
Range on Protein: 142-412
Range on HMM: 1-364/364
Sequence Identity: 20% (82 aa)

LGSGGFGSVYAGVLAN---------GTRLAVKALETGG--GHGG------------------------HKQFVAEVVSLGSISHVNIVRLCGYCVHGSS-
.|||||| || |.. .         |.  ||| . .     .                           .... |.... ...| |||.. |||  ... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEHVANGSLDQWLFDSGKRSLSWESRWKIALGTARGLAYLHE----ECRDP--IMHLDIKPQNILLDEDFT-------------
              .|.| . .|||   |         |. | ..||..|||..|||      |. .  | | |.|..|||.||..|             
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH--------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNADW

-AKVSDFGMSKLLT---SKDITQ--------------VVTGVRGTPGYLAPEWLLNS----------------IATKKCDVYSCGMVLLELISGRRNIQP
 .|..||| |. ..   ..  |.                  ..|||...||| | ..                 ...|||||| |.|| |.....|    
CCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR----

GKLASSGNALDWFFPMWAVNEFKAGRLLDIVDE-------KVRCVEILPLVET------------------LFKVALWCIQDSPSARPSISRVLQML
                     ..     ...         ...|.. |..                     . | . .| .  |..||| ...|. |
--------------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL

Pkinase IRAKm_h.AA Pkinase 136-335 27 4.8e-46 163.88 Pfam 1-209 (293) Show / Hide
Range on Protein: 136-335
Range on HMM: 1-209/293
Sequence Identity: 27% (60 aa)

RGFTQKLGSGGFGSVYAGVLANGTR-LAVKALETGGGHGGHKQFVA-----EVVSLGSISHVNIVRLCGYCVHGSSRLLVYEHVANG----SLDQWLFDS
  . .|.|||.||.|| ..  .  .  ||| ..    |  ... ..     |.  . ...| ||||| ...  ...  .| |.. .|    .|  ..  .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR--HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTW

GKRSL--SWESRWKIALGTARGLAYLHEECRDPIMHLDIKPQNILLDEDFTA----KVSDFGMSKLLTSKDITQVVTGVRGTPGYLAPEWLL-NSIATKK
 ....  |..   .... ..|||.|.|..    |.| |.||.|||.|.. .     |..||| .|..      .  |.. |||.|.|||... ..  ..|
RHGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

CDVYSCGMVLLELISGR
.|..||| .| |...||
VDMWSCGCILYEMLCGR

Kinase IRAKm_h.AA IRAK 138-336 37 1.5e-44 154.36 In-house 1-222 (317) Show / Hide
Range on Protein: 138-336
Range on HMM: 1-222/317
Sequence Identity: 37% (84 aa)

FTQ--KLGSGGFGSVYAGVLANGT-RLAVK---ALETGGGHGGHKQFVA---EVVSLGSISHVNIVRLCGYCVHGSSRLLVYEHVANGSL-DQWLFDSGK
| .  ..|.|||| || |.. | |   |||   . .     .  ..| .   |. .. .. | ||| | |||  ..   |||.  .|||| |.     | 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

RS---LSWESRWKIALGTARGLAYLHEEC-RDPIMHLDIKPQNILLDEDFTAKVSDFGMSKLL--TSKDITQVV-----TGVRGTPGYLAPEWLL--NSI
 .   |||  | .|..|||.|. .||.     || | |||. |||||..||.| .|||.      .|    |..       ||||  |..|| .     .
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

ATKKCDVYSCGMVLLELISGRR
 ||| ||||.| ||||...|.|
LTKKTDVYSFGIVLLEVLTGCR

Kinase IRAKm_h.AA TKL-Unique 138-334 28 1.4e-36 126.55 In-house 1-224 (290) Show / Hide
Range on Protein: 138-334
Range on HMM: 1-224/290
Sequence Identity: 28% (65 aa)

FTQKLGSGGFGSVYAGVLANGTRLAVKALET-GGGHGGHKQ-FVAEVVSLGSIS-HVNIVRLCGYCV----HGSSRLLVYEHVANGSLDQWLFD------
|  |.|.||.|.|| |.  .|.  |.| ..   . .   .| |  ||  .  .  | |||.. |||.    . . . .| | .  |||.  | .      
FWNKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--SGKRSLSWESRWKIALGTARGLAYLHEECRDPIMHLDIKPQNILLDED-----FTAKVSDFGMSKLLTSKDITQVV-------TGVRGTPGYLAPEWL
  . .  |... | |.|.  |.|. ||| .    |.|.|.|..|.|.|..     . .|..||| ||.... . . .        ... |.. ..||| |
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

LN--SIATKKCDVYSCGMVLLELISG
 .  .  ..|.|||| |.|| |....
RMNFCQYSEKSDVYSFGIVLWEIATR

S_TKc IRAKm_h.AA S_TKc 136-412 22 7.3e-34 119.74 SMART 1-231 (231) Show / Hide
Range on Protein: 136-412
Range on HMM: 1-231/231
Sequence Identity: 22% (67 aa)

RGFTQKLGSGGFGSVYAGVLAN-GTRLAVKALETGGGHGGHKQFVAEVVSLGSISHVNIVRLCGYCVHGSSRLLVYEHVAN--GSLDQWLFDSGK----R
  . .|.|.|.||.|| ..  . | . |.| .         ...  |.  | .  | |||.| ..... ..  .| |.. .  |.| . . . |.    .
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF

SLSWESRWKIALGTARGLAYLHEECRDPIMHLDIKPQNILLDEDFTAKVSDFGMSKLLTSKDITQVVTGVRGTPGYLAPEWLLNSIATKKCDVYSCGMVL
 ..    ....  ....|.|.|.     |.| |.||.||||||  . |..|||....|         | . ||| |.||| |  .  ..|||..||| .|
PFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL--GYGKCKCDWWSCGCIL

LELISGRRNIQPGKLASSGNALDWFFPMWAVNEFKAGRLLDIVDEKVRCVEILPLVETLFKVALWCIQDSPSARPSISRVLQ---------ML
 |...|.   .        .    |  .                            . .      | |  |. ||..  .||          .
YEMLCGYPPFP--------QMQMMFKKIG--------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF

Kinase IRAKm_h.AA Dicty4 138-331 31 3.8e-33 108.03 In-house 3-210 (277) Show / Hide
Range on Protein: 138-331
Range on HMM: 3-210/277
Sequence Identity: 31% (66 aa)

FTQKLGSGGFGSVYAGVLANGTRLAVKAL---ETGGGHGGHKQFVAEVVSLGSISHVNIVRLCGYCV----HGSSRLLVYEHVANGSLDQWLFD-----S
..|..|.|.||.|| |    |.  ||| |    ..      . | .||  ...|.| ||. . |.|     | .. . | | .  |.|   | |      
IEQRIGKGSFGEVYKGTW-RGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQ

GKRSLSWESRWK---IALGTARGLAYLHE-ECRDPIMHLDIKPQNILLDEDFTAKVSDFGMSK-LLTSKDITQVVTGVRGTPGYLAPEWLLNSIATKKCD
 . .|.|. . .   .|. .|||...||.  ..  | |.|.|. |.| |.....||.||| |.   . .| ..  ... |||.. ||| . .   . | |
QSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV--IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKAD

VYSCGMVLLEL
||| |.|| |.
VYSFGIVLWEI

Kinase IRAKm_h.AA MLK 138-335 29 5.9e-33 111.7 In-house 3-233 (291) Show / Hide
Range on Protein: 138-335
Range on HMM: 3-233/291
Sequence Identity: 29% (69 aa)

FTQKLGSGGFGSVYAGVLANGT----RLAVKALE-TGGGHGGH-----KQFVAEVVSLGSISHVN----IVRLCGYCVH-GSSRLLVYEHVANGSLDQWL
| ...|||.||.|. |.  | .     .|||. . .     .      ..|  |.  |  .|| |    |... | |   ..  ..| | ...|||   |
FHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNVL

FD-SGKRS-----------LSWESRWKIALGTARGLAYLHEECRDPIMHLDIKPQNILLDE------DFTAKVSDFGMSKLLTSKDITQV---VTGVRGT
 . ..| .            . ..  ..||  |||..|||.. ..|| | |.|..|||.||      . |.|..|||     ||.|..|     .. .||
HGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFG-----TSRDWHQMCTNMMSNAGT

PGYLAPEWL---LNSIATKKCDVYSCGMVLLELISGR
. . ||| .    ..  ..||||.| |.|| |.....
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE

Kinase IRAKm_h.AA Dicty4-Unclassified 138-334 32 2.2e-32 108.18 In-house 3-204 (263) Show / Hide
Range on Protein: 138-334
Range on HMM: 3-204/263
Sequence Identity: 32% (67 aa)

FTQKLGSGGFGSVYAGVLANGTRLAVKALETGGGHGG---HKQFVAEVVSLGSISHVNIVRLCGYCVHG----SSRLLVYEHVANGSLDQWLF---DSGK
  | .| | |  |. |.   |   ||| .  .         . | .||  ||||.| | |.. |||.      |    | |    | |           .
IDQFIGKGHFSKVHKGNW-KGKDVAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQ

RSLSWES--RWKIALGTARGLAYLHEECRDPIMHLDIKPQNILLDEDFTAKVSDFGMSKLLTSKDITQVVTGVRGTPGYLAPEWLLNSIATKKCDVYSCG
.... ..    |.|.  |.|...||   |. . | |||  |||.| .| .|. |||.|      | ..  | . |||   .|| |     . | |||| .
QPIKLDDTLIIKYAFDIAQGMQHLH--TRN-FIHRDIKSSNILMDKHFNIKIADFGISRVI---DFNFNMTTIAGTPKWESPECLMHESYNQKSDVYSYA

MVLLELISG
|.| ||. |
MMLYELATG

Kinase IRAKm_h.AA LRRK 136-336 24 6.8e-30 102.93 In-house 1-281 (351) Show / Hide
Range on Protein: 136-336
Range on HMM: 1-281/351
Sequence Identity: 24% (69 aa)

RGFTQKLGSGGFG-SVYAGVLAN---------------------------GTRLAVKALETG---------------------------------GGHGG
  . ...|.|||| .|| . . .                           ..  |.| ....                                 . .  
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

HKQFVAEVVSLGSISHVNIVRLCGYCVHGSSRLLVYEHVANGSLDQWLFDSGKRS-------LSWESRWKIALGTARGLAYLHEECRDPIMHLDIKPQNI
.  |  ||. . .  | ||| | |.| |   . .| | . .|.|.. |... . .       .||  . ||||  |.|..|||  .. || | | |. ||
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLH-SHNPPIIHRDLKSPNI

LL---D---------EDFTAKVSDFGMSKLLTSKDITQVVTGVRGTPGYLAPEWLL---NSIATKKCDVYSCGMVLLELISGR-R
||   .         .. .||..||| | .  . . . |. |. |.||..||| .    ..  | | |.|| ||.| ||.... .
LLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHH

Kinase IRAKm_h.AA LISK 141-336 28 2e-29 92.62 In-house 1-237 (296) Show / Hide
Range on Protein: 141-336
Range on HMM: 1-237/296
Sequence Identity: 28% (69 aa)

KLGSGGFGSVYAGVLA-NGTRLAVKALET----GGGHGGHKQFVAEVVSLGSISHVNIVRLCGYCVH-GSSRLLVYEHVANGSLDQWLFDSG--KRSLSW
..|.|.||.|| | .   |.  |.| ...           | .  ||  . ...| |||.  | |.|  ..  .| | .  | | | |.|..  |  |.|
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

ESRWKIALGTARGLAYLHEECRDPIMHLDIKPQNILLD----EDFTAKVSDFGMSKLLTSKD-------------------------ITQVVTGVRG---
. | ||||. |.|..|||. .   |.| | | .|.|..    .....|| |||  .... ..                         | .   ..|    
PQRVKIALDIACGMSYLHSMN---IIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

----TPGYLAPEWLLNSIATKKCDVYSCGMVLLELISGRR
    ||   ||| || .  . .|||.| |.||.|.| ...
TICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEIITRVK

Kinase IRAKm_h.AA STE 138-335 22 1.3e-28 98.24 In-house 1-265 (359) Show / Hide
Range on Protein: 138-335
Range on HMM: 1-265/359
Sequence Identity: 22% (61 aa)

FTQ--KLGSGGFGSVYAGVLAN----------------GTRLAVKALETGGG----------------HGGHKQFVAEVVSLGSIS--HVNIVRLCGYCV
..   |.|.|.||.|| ..  .                |.. |.| ..                    |  ..|.  |.  .   .  | |||.  |...
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

HG-------SSRLLVYEHVANGSLDQWLFDSGKRSLSW-----------ESRW-KIALGTARG-LAYLHEECRDPIMHLDIKPQNILLDEDFTAKVSDFG
..       ..  .. |....||||. .   ...  .            ||   .|.  . .| |.|||.     |.| ||||.||||     .| .|||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG

MSKLLTSK--------------DITQVVTGVRGTPGYLAPEWLLNSI------ATKKCDVYSCGMVLLELISGR
 .. ||..              .. |  . . ||| . ||| ...         . |||..| | ...|.. |.
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGK

Kinase IRAKm_h.AA LISK-DD1 181-336 33 1.9e-20 70.77 In-house 44-229 (290) Show / Hide
Range on Protein: 181-336
Range on HMM: 44-229/290
Sequence Identity: 33% (63 aa)

EVVSLGS---ISHVNIVRLCGYCVH-------------GSSRLLVYEHVANGSLDQWLFDSG-----------KRSLSWESRWKIALGTARGLAYLHEEC
|.  | .   |.| |||.  | |.|             .||  .| | .  | | . |.. .           |  ..|..| ||||. | . ||||.  
EIKMLKNLLNIRHPNIVQFIGICEHPLASPSLVNRLLNESSLYIVTEFIEGGDLHWYLKNTPFDDTPEQYIHHKIPIPWKLRVKIALDIACAMAYLHS--

RDPIMHLDIKPQNILLDED----FTAKVSDFGMSKLLTSK--D-ITQVVTGVRGTPGYLAPEWLLNSIATKKCDVYSCGMVLLELISGRR
.. |.| | | .|||.||      ..|| |||  . .. |  . .    | . ||..  ||| .| .     |||.| ||||||||....
KN-IIHRDLKSKNILVDENGDSQWRIKVCDFGFARMFEQKKNQQNNRHMTIC-GTDNWMAPEVILGMSYDWSCDVFSFGMVLLELITRKK

Kinase IRAKm_h.AA Pkinase_Tyr 138-251 29 5.7e-19 64.87 Pfam 3-129 (270) Show / Hide
Range on Protein: 138-251
Range on HMM: 3-129/270
Sequence Identity: 29% (38 aa)

FTQKLGSGGFGSVYAGVLA-----NGTRLAVKALETGGGHGG--HKQFVAEVVSLGSI-SHVNIVRLCGYCV-HGSS--RLLVYEHVANGSLDQWLFDS-
| .|||.| ||.|| |..      ...  ||| |  |  |    .. | .|.  . .. .| ||||| | |. .| .   ..| |....|.|.  | .  
FGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRKHR

-GKRSLSWESRWKIALGTARGLAYLHE
 .|..|. .   ....  |.|..||..
EDKQPLTMKDLLQMCWQIAKGMEYLES

Kinase IRAKm_h.AA TyrKc 138-412 22 9.6e-18 64.2 SMART 3-280 (280) Show / Hide
Range on Protein: 138-412
Range on HMM: 3-280/280
Sequence Identity: 22% (68 aa)

FTQKLGSGGFGSVYAGVLANGTRLAVKALETGGGHGGHKQFVAEVVSLGSI--SHVNIVRLCGYCVHG-------SSRLLVYEHVANGSLDQWLFDSGKR
. .|||.| || || |..   .  ||| |  .     .. |  |   . ..  .| ||||| |.|...          ..| |....|.|.. | .....
LGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRPK

SLSWESRWKIALGTARGLAYLHEECRDPIMHLDIKPQNILLDEDFTAKVSDFGMSKLLTSK-------DITQVVT--GVR--GTPGYLAPEWLLNSIATK
 |...   ....  |.| .|||.    .. | |.   |.|..|..|.|.||||.|. ....       |   . .  | .       .||| .  .. | 
-LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KCDVYSCGMVLLELISGRRNIQPG-----KLASSGNALDWFFPMWAVNEFKAGRLLDIVDEKVRCVEILP-----LVETLFKVALWCIQDSPSARPSISR
| ||.| | .. |. .      ||     . ..            ...  |.|. ... ..        |       . .... ..| .  |. ||. | 
KSDVWSFGVCMWEIFTYGQQPYPGMIQQMMSNQE-----------VIEYVKQGYRMPQPPNDY------PMSFVCCPDEMYQIMKQCWHEDPEDRPTFSE

VLQML
. . .
IHECF

Kinase IRAKm_h.AA Pkinase_Tyr 266-333 27 3.7e-07 24.88 Pfam 141-209 (270) Show / Hide
Range on Protein: 266-333
Range on HMM: 141-209/270
Sequence Identity: 27% (19 aa)

NILLDEDFTAKVSDFGMSKLLTSKDIT-QVVTGVRGTPGYLAPEWLLNSIATKKCDVYSCGMVLLELIS
|.|..|....|..|||........|   .. .| .     .||| . ... | | ||.| | .. |...
NCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFT

Kinase IRAKm_h.AA LISK-DD1 141-168 39 0.000482 10.79 In-house 1-27 (290) Show / Hide
Range on Protein: 141-168
Range on HMM: 1-27/290
Sequence Identity: 39% (11 aa)

KLGSGGFGSVYAGVLANGTRLAVKALET
. |.|.||.|| |.. .||  |.| ...
EIGKGSFGKVYKGCY-FGTPVAIKKIHK

Kinase IRAKm_h.AA Dicty4-Unclassified 393-412 35 0.000992 8.61 In-house 244-263 (263) Show / Hide
Range on Protein: 393-412
Range on HMM: 244-263/263
Sequence Identity: 35% (7 aa)

WCIQDSPSARPSISRVLQML
||  ..|  ||..  . | |
WCWHNDPNKRPTMNQIIQYL

Kinase IRAKm_h.AA LISK-DD1 387-412 30 0.006699 6.61 In-house 265-290 (290) Show / Hide
Range on Protein: 387-412
Range on HMM: 265-290/290
Sequence Identity: 30% (8 aa)

LFKVALWCIQDSPSARPSISRVLQML
. ....||.   |. ||| . ..| |
FMDLCMWCCKYDPNNRPSFKEIVQTL

Kinase IRAKm_h.AA LISK 385-412 25 0.046904 2.24 In-house 269-296 (296) Show / Hide
Range on Protein: 385-412
Range on HMM: 269-296/296
Sequence Identity: 25% (7 aa)

ETLFKVALWCIQDSPSARPSISRVLQML
. .......|.   |. ||| . ..| |
PPFLDLCFDCCKYDPKNRPSFKEIVQWL

Kinase IRAKm_h.AA Dicty4 393-414 33 0.202096 0.7 In-house 254-277 (277) Show / Hide
Range on Protein: 393-414
Range on HMM: 254-277/277
Sequence Identity: 33% (8 aa)

WCIQDSPSARPSISRVLQM--LDG
||   .|. ||| . ..|   |. 
WCWDHDPQHRPSFEEIIQRRILEH

Kinase IRAKm_h.AA Pkinase 385-412 26 2.967128 1.98 Pfam 264-293 (293) Show / Hide
Range on Protein: 385-412
Range on HMM: 264-293/293
Sequence Identity: 26% (8 aa)

ETLFKVALWCIQDSPSARPSISRVLQM--L
|.. ..  ||..  |. ||..  .||   .
EECKDFIKWCLCKDPKKRPTAEQILQHPWF