Gene IRAKg_u-1 (S.moellendorffii)

IRAKg_u-1

Species: S.moellendorffii
Alias: IRAKg_u-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKg

Sequence

Name Sequence Type Origin Length Description Download
IRAKg_u-1.AA Protein None 786 None Fasta, JSON
IRAKg_u-1.NA RNA None 2361 None Fasta, JSON
IRAKg_u-1.kin_dom Protein Kinase Domain None 191 None Fasta, JSON

Protein domain

Protein domains of IRAKg_u-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
B_lectin IRAKg_u-1.AA B_lectin 122-162 42 1.3e-14 51.79 Pfam 67-113 (137) Show / Hide 
Range on Protein: 122-162
Range on HMM: 67-113/137
Sequence Identity: 42% (20 aa)

ATASLEETGNFVLL-DRS--SDRIWQS--FDFPTDTLLPGQELRG-N
..| . ..||.||. | .  .. .|||  ||.||||.|||. |.  |
CRAQMQDSGNLVLYDDNNDSNNVLWQSNTFDHPTDTWLPGMKLGWDN
B_lectin IRAKg_u-1.AA B_lectin 25-149 25 2e-06 21.58 SMART 1-126 (126) Show / Hide 
Range on Protein: 25-149
Range on HMM: 1-126/126
Sequence Identity: 25% (36 aa)

DKLGAGQPPWMSLNSTFA--FGFHTSDGIGELFTLAIWHQRTG----TVVWEA---TEALIKNGSTTEKPKIKVGKTGELELKETGLIVTDKSMTVWLVR
| .  .   . | ||.|   .||.| ..    ... ||.        |||| |   .. . ..|  .   . . .. |.| .            .||   
DNTLSSGQTLVSGNSLFEFYLGFFTFIMQ---WCNGIWYKNISNKQRTVVWVAQPNRDNPVHDG--NNSCYLTMQSDGNLVIYD--------NRPVWSSN

CE-NCSIATASLEETGNFVLLDRS-SDR---IWQSFDFP
.  | .  .| | ..||||. | . .|    ||||||.|
TTRNNGNYVAVLQDDGNFVIYDPDDNDSGNFIWQSFDHP
S_locus_glycop IRAKg_u-1.AA S_locus_glycop 247-315 23 2.6e-09 34.06 Pfam 49-117 (117) Show / Hide 
Range on Protein: 247-315
Range on HMM: 49-117/117
Sequence Identity: 23% (16 aa)

DTSVIRRLTLEKNGMLRSYSCGSGEKRWRVVWQSALLECEIFGTCGAFGLCGYKPRKSCSCPPGFHAVD
..|.. |.|.  .| |  .      ..|.. | .   .|.. ..||..|.|  .    |.| .||.   
NNSIYSRFTMSSEGYLQRFTWNPNSQDWNLFWYAPKDQCDYYRRCGPYGYCDMNTSPMCNCIKGFVPKN
PAN_AP IRAKg_u-1.AA PAN_AP 337-417 17 0.000247 21.1 SMART 1-85 (85) Show / Hide 
Range on Protein: 337-417
Range on HMM: 1-85/85
Sequence Identity: 17% (16 aa)

SSASKMVEVQRAMYVGNLLQQ----LSKDPISLEQCKVSCLKDCRCLGATYMLAGTKRCSLLGGEDGRLFNGV-------QAMERTSIALLK
..   .| . .. .     ..    . .  .|||.|.  ||..|.| ...|    || | |   .|..|..         ........   .
CCDDCFVRMPNMKL---FSPIVNWVDVI-VMSLEECMQKCLNNCSCRSFMYYN--TKGCHLWS-WDSHLGDPRQFKRFMKFPNQGVDYYEKN
Kinase IRAKg_u-1.AA TKL 493-746 21 9.2e-62 211.51 In-house 1-364 (364) Show / Hide 
Range on Protein: 493-746
Range on HMM: 1-364/364
Sequence Identity: 21% (80 aa)

LGAGGFGSVYKGVLPD---------MTVVAVKTLEG---------------------------AASHGEKQFKAEVATLGRVHHVNLVKLLGYCAEGSH-
.| |||| ||||..            ..||||..                              ||. ..... |.  . | .| |.|...||| .... 
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEFLSNGS-LDQECSDLWGTRYSIALGVAKGITYLHEECY-----DCILHCDIKPQNVLLDENFC--------------PKVSD
              .|.|. ..|| |..     |  | ..||..|.|. ||| .         |.|.|.|..|.|.|||.               .|..|
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNADWCCKICD

FGLAKLTDKE------------------RALDVTTIRGTRGYMAPEWVGDR----------------PITSKVDVYSYGMVLLELLSGNDKSRIGQNRYF
|||..  ...                  ..    |..|| ..||||   .                 . . |.||||.|.|| |.|..          |.
FGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR-------PYY

PVWAFQKYVA----GELHAIADPGLKSLEW-------------NEFERMIKVAFWCIQLDARSRPSMSRVVQML
  . .. ...     ..  ..| ||. .               .  ..|.| . .| . |...|||...... |
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAKg_u-1.AA IRAK 488-677 37 3.1e-51 176.53 In-house 2-220 (317) Show / Hide 
Range on Protein: 488-677
Range on HMM: 2-220/317
Sequence Identity: 37% (83 aa)

HFSCKLGAGGFGSVYKGVLPDMT-VVAVKTLEGAAS----HGEKQFKA---EVATLGRVHHVNLVKLLGYCAEGSHRLLVYEFLSNGSLDQ--ECSD---
| . ..| |||| ||.|..   | ..||| |   |.      ...| .   |. .. | .| |.| |.|||.|..   |||....||||    .| |   
HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQC

-L----WGTRYSIALGVAKGITYLHEEC-YDCILHCDIKPQNVLLDENFCPKVSDFGLAKLT----DKERALD----VTTIRGTRGYMAPEWVG--DRPI
 .    | .| ||..| |.|| .||.      | | |||. |.|||..| || .||||.       .||..      . ..|||  ||.||      . .
PPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQL

TSKVDVYSYGMVLLELLSG
| |.|||| | ||||.|.|
TKKTDVYSFGIVLLEVLTG
Kinase IRAKg_u-1.AA Pkinase 487-746 23 1.4e-46 165.8 Pfam 1-293 (293) Show / Hide 
Range on Protein: 487-746
Range on HMM: 1-293/293
Sequence Identity: 23% (72 aa)

NHFSCKLGAGGFGSVYKGVLPDMTV-VAVKTLEGAASHGEKQFKA-----EVATLGRVHHVNLVKLLGYCAEGSHRLLVYEFLSNG----SLD------Q
 |.  |.|.|.||.|||..  .    ||||...   .  ... ..     |.. . |..| | |.|.... ...|  .| |.. .|    .|       .
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

ECSD--LWGTRYSIALGVAKGITYLHEECYDCILHCDIKPQNVLLDENFCP----KVSDFGLAKLTDKERALDVTTIRGTRGYMAPEWVG-DRPITSKVD
...    . .  .... ...|. |.|..    |.|.|.||.|.|.|.|  .    |..||||||. |  .    ||. ||..|||||..  ......|||
HGCFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSYGMVLLELLSGNDKSRIGQNRYFPVWAFQK----YVAGELHAIADPGLKSLEWNEF-----------------------ERMIKVAFWCIQLDARSR
..|.| .| |.|.|.           | .  ..      . ... |.  . . |.....                       | ....  ||...|  .|
MWSCGCILYEMLCGR-----------PPFP-GHCWHDN-HDQMQMICRIMGPPLHFDWPWWCSISYFFFRHWHFHWTFHNWSEECKDFIKWCLCKDPKKR

PSMSRVVQM--L
|.   ..|   .
PTAEQILQHPWF
Kinase IRAKg_u-1.AA TKL-Unique 489-677 29 5.3e-38 131.63 In-house 1-224 (290) Show / Hide 
Range on Protein: 489-677
Range on HMM: 1-224/290
Sequence Identity: 29% (66 aa)

FSCKLGAGGFGSVYKGVLPDMTVVAVKTLE-GAASHGE--KQFKAEVATLGRVH-HVNLVKLLGYCA----EGSHRLLVYEFLSNGSLDQECSD------
|. |.|.||.|.||||. .  . ||.|...  . |. |  . |. || .. . | | |.|.. |||.      ... .| |... |||.   ..      
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--------LWGTRYSIALGVAKGITYLHEECYDCILHCDIKPQNVLLDEN-----FCPKVSDFGLAKLTDKERALDVTTI--------RGTRGYMAPEWV
         .  |...|. .|.|  ||| .    |.|.|.|..|.|.|.|     .  |..||||.|. .|. .  ....         |.  .||||  
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

GD--RPITSKVDVYSYGMVLLELLSG
 .    .. |.||||.|.|| |....
RMNFCQYSEKSDVYSFGIVLWEIATR
Kinase IRAKg_u-1.AA MLK 487-677 25 6e-35 118.71 In-house 1-232 (291) Show / Hide 
Range on Protein: 487-677
Range on HMM: 1-232/291
Sequence Identity: 25% (59 aa)

NHFSCKLGAGGFGSVYKGVLPDMT----VVAVKTLE------GAASHGEKQFKAEVATLGRVHHVN----LVKLLGYCAE-GSHRLLVYEFLSNGSLDQE
  |. ..|.|.||.|.||.   ..    .||||  .      . ..   ..|. |.  | .. | |     ....| |.. ..| ..| |....|||   
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

CSDL------------------WGTRYSIALGVAKGITYLHEECYDCILHCDIKPQNVLLDE------NFCPKVSDFGLAK-LTDKERALDVTTIRGTRG
. .                    .   ..|| .|.|. |||..  . | | |.|..|.|.||      .   |..|||... .....     .  .||  
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC--TNMMSNAGTYA

YMAPEWV---GDRPITSKVDVYSYGMVLLELLSG
.||||        . . |.||.|.|.|| |.|..
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTR
Kinase IRAKg_u-1.AA Dicty4 488-675 30 1e-34 113.34 In-house 2-211 (277) Show / Hide 
Range on Protein: 488-675
Range on HMM: 2-211/277
Sequence Identity: 30% (65 aa)

HFSCKLGAGGFGSVYKGVLPDMTVVAVKTL----EGAASHGEKQFKAEVATLGRVHHVNLVKLLGYCA----EGSHRLLVYEFLSNGSL-----D-----
 .  ..| |.||.||||     . |||| |    ... .   . |..||. ..   | |.....|.|     . .  . | |... |.|     |     
NIEQRIGKGSFGEVYKGTWR-GKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQ

-QECSDLWGTRYS---IALGVAKGITYLHE-ECYDCILHCDIKPQNVLLDENFCPKVSDFGLAKLTDKERALDV--TTIRGTRGYMAPEWVGDRPITSKV
 |. .  |... .   .|. .|.|...||.  .   |.| |.|. | | |.|.  ||.||||...  |.  .    .|  || ..||||    .| ..|.
QQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNP--VIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKA

DVYSYGMVLLELL
||||.|.|| |.|
DVYSFGIVLWEIL
Kinase IRAKg_u-1.AA S_TKc 487-746 22 1.8e-31 111.77 SMART 1-231 (231) Show / Hide 
Range on Protein: 487-746
Range on HMM: 1-231/231
Sequence Identity: 22% (64 aa)

NHFSCKLGAGGFGSVYKGVLPD-MTVVAVKTLEGAASHGEKQFKAEVATLGRVHHVNLVKLLGYCAEGSHRLLVYEFLSN--GSLDQECSDLWG------
 ..  |.| |.||.|||..  .   .||.| .        .... |.. | . || |.|||.... . .|  .| |....  |.| .   .  .      
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

---TRYSIALGVAKGITYLHEECYDCILHCDIKPQNVLLDENFCPKVSDFGLAKLTDKERALDVTTIRGTRGYMAPEWVGDRPITS-KVDVYSYGMVLLE
   .  ...  ..... |.|.     |.|.|.||.|.||||  . |..|||||..         ||. ||. ||||| .   . .  |.|..| | .| |
FPEHARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCILYE

LLS-----GNDKSRIGQNRYFPVWAFQKYVAGELHAIADPGLKSLEWNEFERMIKVAFWCIQLDARSRPSMSRVVQ---------ML
.|.       .  .. ..                                . ..     | | | . ||.   . |          .
MLCGYPPFP-QMQMMFKKIG-----------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKg_u-1.AA TK 487-676 16 6.9e-30 96.78 In-house 1-389 (486) Show / Hide 
Range on Protein: 487-676
Range on HMM: 1-389/486
Sequence Identity: 16% (64 aa)

NHFSCKLGAGGFG---SVYKGVLPDM--------------------------TVVAVKTLEGAASHGEKQFKA--------------EVATLGRVH----
 ..  |||.| ||    |||| . ..                          | ||||.|   ... ...|..              |.. .   .    
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

-HVNLVKLLGYCAEG------------SHRLLVYEFLSNGS----LD---QECS----------------------------------------------
 | |.|.|.|.| .|             . ..| |. ..|.    |.   ..|.                                              
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

---------------DLWG----------------TRYSIALGVAKGITYLHEE----CYDCILHCDIKPQNVLLDENFC-----------PKVSDFGLA
               ||.                 ..  ... .|.|  |||.         . | |.   |.|..||              |..||||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

K-----LTDKERALDVTTIRGTRG----------------------------YMAPEWVGDRP---------ITSKVDVYSYGMVLLELLS
.     |. .    |  . ....|                            .|||| . ||           |.| ||.|.| .. |...
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAKg_u-1.AA LRRK 477-677 22 9.3e-30 102.45 In-house 1-278 (351) Show / Hide 
Range on Protein: 477-677
Range on HMM: 1-278/351
Sequence Identity: 22% (66 aa)

FSYEQLEVATNHFSCKLGAGGFG-SVYKGVLPD---------------------------MTVVAVKTLEGA----------------------------
. .|..          .| |||| .||.. . .                            . ||.|...                              
LKIEEQ----------IGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDM

------ASHGEKQFKAEVATLGRVHHVNLVKLLGYCAEGSHRLLVYEFLSNGSLDQECS----D-L--------WGTRYSIALGVAKGITYLHEECYDC-
      ...    |  ||. . . .| |.|.|.|.| .  .. .| |....|.|.. ..    | .        |.... ||| .|||. |||       
DQNHEDCCRAFREFRHEVWIMSHLNHPNIVSLKGFCIH--PLCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH---NP

-ILHCDIKPQNVLL---D---------ENFCPKVSDFGLAK--LTDKER-ALDVTTIRGTRGYMAPEWVGDR---PITSKVDVYSYGMVLLELLSG
 |.|.| |. |.||   .         .. | |..|||.     ....  | ...   |. |.|||| ...      | |||.||.||.| |||..
PIIHRDLKSPNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAKGCV---GNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTR
Kinase IRAKg_u-1.AA LISK 492-674 28 1.4e-28 89.79 In-house 1-232 (296) Show / Hide 
Range on Protein: 492-674
Range on HMM: 1-232/296
Sequence Identity: 28% (66 aa)

KLGAGGFGSVYKGVLP-DMTVVAVKTLEG-----AASHGEKQFKAEVATLGRVHHVNLVKLLGYCAE-GSHRLLVYEFLSNGSLDQECSDL--------W
..| |.||.|||| .  . .|.|.| ..           .| .. ||... .  | | |.  | | .  ..  .| |. . | | |  .|         |
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYINGGDLHQYLKDMDKHKIPLPW

GTRYSIALGVAKGITYLHEECYDCILHCDIKPQNVLLDEN----FCPKVSDFGLAKLTDKER---------------------------------ALDVT
  | .|||..|.| .|||.    .|.| | | .|.|..||    .  || |||.|.. |.|.                                 .    
PQRVKIALDIACGMSYLHSM---NIIHRDLKSKNCLVRENDNNQWRIKVCDFGFARMMDCENNSPCNMPREDESDPCMDNDMPMKRKIPKKCMNQRKRRM

TIRGTRGYMAPEWVGDRPITSKVDVYSYGMVLLEL
|| ||   |||| . ..  . ..||.|.|.||.|.
TICGTPYWMAPEMLLGQSYDESCDVFSFGIVLCEI
Kinase IRAKg_u-1.AA CZAK 488-679 28 1.1e-25 90.36 In-house 2-220 (279) Show / Hide 
Range on Protein: 488-679
Range on HMM: 2-220/279
Sequence Identity: 28% (64 aa)

HFSCKLGAGGFGSVYKGVLPDMTVVAVKTLEGAASHGEKQ------FKAEVATLGRVHHVNLVKLLGYCAEGS--HRLLVYEFLSNGSLDQ---ECSDLW
 |    | | || |||..    ..||.| .                |  ||. .    | | |  || | |.   |.  | |.   |||..   . . . 
KFGQTIGQGFFGEVYKAYWRG-KDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFYH

GT----RYSIALGVAKGITYLHEECYD-CILHCDIKPQNVLLDENFC-------------PKVSDFGLAKLTDKERALDVTTIRGTRGYMAPE-WVGDRP
      . ..|. .|.|  |||       ||| |   .|.|||..                |..|||| ..  .| . . |   |   .||||   |.  
KQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREM-MEQPFEMTQTMGCLCWMAPECFKGEN-

ITSKVDVYSYGMVLLELLSGND
 | ||||||.||.| ... . .
YTEKVDVYSFGMILWCIITCDQ
Kinase IRAKg_u-1.AA TyrKc 487-746 23 1.4e-24 88.93 SMART 1-280 (280) Show / Hide 
Range on Protein: 487-746
Range on HMM: 1-280/280
Sequence Identity: 23% (69 aa)

NHFSCKLGAGGFGSVYKGVLPDMTVVAVKTLEGAASHGEKQFKAEVATLGRV--HHVNLVKLLGYCAEG-------SHRLLVYEFLSNGSLD---QECS-
 ..  ||| | || ||||..   . ||||.|   |   .. |  |   . ..  || |.|.|.|.| ..          ..| |. ..|.|.   ...  
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

-DLWGTRYSIALGVAKGITYLHEECYDCILHCDIKPQNVLLDENFCPKVSDFGLAKLTDKE----RALDVTTIR---GTRG-----YMAPEWVGDRPITS
   . .  |... .|.|  |||.    .. | |.   |.|..||.. |.|||||..  . .     . |. . .   |...      ||||   ..  |.
KLCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKFTT

KVDVYSYGMVLLELLSGNDKSRIG---QNRYFPVWAFQKYVAGELHAIADPGLKSLEWN----EFERMIKVAFWCIQLDARSRPSMSRVVQML
| ||.|.| .. |...  ..   |   |    .  ....  .|.   . . ..   .        . | ..  .| . |. .||..| ... .
KSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDY---P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase IRAKg_u-1.AA Dicty4-Unclassified 582-678 37 5.5e-22 72.06 In-house 114-205 (263) Show / Hide 
Range on Protein: 582-678
Range on HMM: 114-205/263
Sequence Identity: 37% (36 aa)

IALGVAKGITYLHEECYDCILHCDIKPQNVLLDENFCPKVSDFGLAKLTDKERALDVTTIRGTRGYMAPEWVGDRPITSKVDVYSYGMVLLELLSGN
.|. .|.|. .||      . | |||  |.|.| .|  |. |||..  .|    .  ||| ||    .||       ..| |||||.|.| ||. |.
YAFDIAQGMQHLHTR---NFIHRDIKSSNILMDKHFNIKIADFGISRVIDFNFNM--TTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGD
Kinase IRAKg_u-1.AA Pkinase_Tyr 488-569 34 3.1e-21 72.56 Pfam 2-95 (270) Show / Hide 
Range on Protein: 488-569
Range on HMM: 2-95/270
Sequence Identity: 34% (32 aa)

HFSCKLGAGGFGSVYKGVLP-----DMTVVAVKTLEGAASHGE---KQFKAEVATLGRV-HHVNLVKLLGYCA-EGSH--RLLVYEFLSNGSLD
.|  |||.| ||.||||..      . . ||||.|   |.| .   . | .|....    || |.|.|.| |  .| .   ..| |.  .|.|.
TFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLL
Kinase IRAKg_u-1.AA Dicty4-Unclassified 488-568 35 6.5e-08 23.15 In-house 2-89 (263) Show / Hide 
Range on Protein: 488-568
Range on HMM: 2-89/263
Sequence Identity: 35% (32 aa)

HFSCKLGAGGFGSVYKGVLPDMTVVAVKTL-EGAASHG---EKQFKAEVATLGRVHHVNLVKLLGYCAEG-SHR---LLVYEFLSNGSL
     .| | |  |.||.      |||| . |.  .      . ||.||. || . | ||||. |||    ||.     | ||.  | |
QIDQFIGKGHFSKVHKGNWKGKD-VAVKKFNENKFKFREEMIQDFKKEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNL
Kinase IRAKg_u-1.AA Pkinase_Tyr 581-676 29 1e-06 23.26 Pfam 115-209 (270) Show / Hide 
Range on Protein: 581-676
Range on HMM: 115-209/270
Sequence Identity: 29% (29 aa)

SIALGVAKGITYLHEECYDCILHCDIKPQNVLLDENFCPKVSDFGLAKLTDKERALDVTTIRGTRG---YMAPEWVGDRPITSKVDVYSYGMVLLELLS
.... .|||  ||..     . | |.   |.|..||.. |..|||||..  ..    ...  |..     ||||   ..  |.| ||.|.| .. |...
QMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYY-YRKRGGGKLPIKWMAPECINYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAKg_u-1.AA LISK 722-746 36 4.4e-05 12.25 In-house 272-296 (296) Show / Hide 
Range on Protein: 722-746
Range on HMM: 272-296/296
Sequence Identity: 36% (9 aa)

IKVAFWCIQLDARSRPSMSRVVQML
....|.|. .| ..||| . .|| |
LDLCFDCCKYDPKNRPSFKEIVQWL
Kinase IRAKg_u-1.AA LRRK 727-748 36 0.000476 10.2 In-house 330-351 (351) Show / Hide 
Range on Protein: 727-748
Range on HMM: 330-351/351
Sequence Identity: 36% (8 aa)

WCIQLDARSRPSMSRVVQMLEE
.| | | ..||..| .|. |..
HCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAKg_u-1.AA TK 728-746 31 0.000516 8.5 In-house 468-486 (486) Show / Hide 
Range on Protein: 728-746
Range on HMM: 468-486/486
Sequence Identity: 31% (6 aa)

CIQLDARSRPSMSRVVQML
| ..|.. ||..| ....|
CWHYDPEDRPTFSQLHEQL
Kinase IRAKg_u-1.AA MLK 728-746 42 0.002431 7.6 In-house 273-291 (291) Show / Hide 
Range on Protein: 728-746
Range on HMM: 273-291/291
Sequence Identity: 42% (8 aa)

CIQLDARSRPSMSRVVQML
| . |...|||.. .|| |
CWNQDPHKRPSFRQIVQHL
Kinase IRAKg_u-1.AA Dicty4-Unclassified 727-746 40 0.008485 5.37 In-house 244-263 (263) Show / Hide 
Range on Protein: 727-746
Range on HMM: 244-263/263
Sequence Identity: 40% (8 aa)

WCIQLDARSRPSMSRVVQML
||   | . ||.|  ..| |
WCWHNDPNKRPTMNQIIQYL
Kinase IRAKg_u-1.AA Dicty4 735-748 37 0.033284 3.35 In-house 262-277 (277) Show / Hide 
Range on Protein: 735-748
Range on HMM: 262-277/277
Sequence Identity: 37% (6 aa)

SRPSMSRVVQM--LEE
.|||.. ..|   ||.
HRPSFEEIIQRRILEH
Kinase IRAKg_u-1.AA Pkinase_Tyr 728-746 31 0.145402 5.92 Pfam 252-270 (270) Show / Hide 
Range on Protein: 728-746
Range on HMM: 252-270/270
Sequence Identity: 31% (6 aa)

CIQLDARSRPSMSRVVQML
| . |.  ||..| ....|
CWHYDPEDRPTFSEIHEQL