Gene IRAKf_g-1 (S.moellendorffii)

IRAKf_g-1

Species: S.moellendorffii
Alias: IRAKf_g-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKf

Sequence

Name Sequence Type Origin Length Description Download
IRAKf_g-1.AA Protein None 561 None Fasta, JSON
IRAKf_g-1.NA RNA None 1686 None Fasta, JSON
IRAKf_g-1.kin_dom Protein Kinase Domain None 204 None Fasta, JSON

Protein domain

Protein domains of IRAKf_g-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
LRRNT_2 IRAKf_g-1.AA LRRNT_2 3-37 36 1.9e-09 33.56 Pfam 7-46 (46) Show / Hide 
Range on Protein: 3-37
Range on HMM: 7-46/46
Sequence Identity: 36% (15 aa)

ALLAFKEGIQE-AQFL---LGDWRRSD--ATPCNWTGVECN
|||||| ...         | .|  |.  ...|.||||.|.
ALLAFKSSLNDSDP-HHGVLSSWNPSSSDSDCCSWTGVTCD
LRR_1 IRAKf_g-1.AA LRR_1 42-64 25 0.971773 6.79 Pfam 1-26 (26) Show / Hide 
Range on Protein: 42-64
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

RVETLNLPRF---HLVGVISPE-IGKL
. ..|.| ..   .|.| |.|. . .|
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAKf_g-1.AA LRR_1 66-88 37 0.000484 18.5 Pfam 1-26 (26) Show / Hide 
Range on Protein: 66-88
Range on HMM: 1-26/26
Sequence Identity: 37% (10 aa)

KLRRLGLHN-N--MISGKIPPS-LGNC
.|..| | . |   ..|.|||| . |.
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAKf_g-1.AA LRR_1 90-112 25 0.04869 11.4 Pfam 1-26 (26) Show / Hide 
Range on Protein: 90-112
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

DLRAVYLRD-N--LLSGSLPAE-LGRL
 |.  .|.. |   |.|..| . .  |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAKf_g-1.AA LRR_1 114-136 44 0.005181 14.85 Pfam 1-26 (26) Show / Hide 
Range on Protein: 114-136
Range on HMM: 1-26/26
Sequence Identity: 44% (12 aa)

NLKVFDVSE-N--SLTGPIPAS-MERL
||.. |.|  |  .||| || |    |
NLQHLDLSGCNCCNLTGHIPPSCF-NL
LRR_1 IRAKf_g-1.AA LRR_1 138-159 25 0.378998 8.24 Pfam 1-26 (26) Show / Hide 
Range on Protein: 138-159
Range on HMM: 1-26/26
Sequence Identity: 25% (7 aa)

DLVFLNVSN-N--FLTGSVTG--LAKF
 |  |..|. |   |||..    . ..
NLQHLDLSGCNCCNLTGHIPPSCF-NL
Kinase IRAKf_g-1.AA TKL 270-536 22 4e-69 235.97 In-house 1-364 (364) Show / Hide 
Range on Protein: 270-536
Range on HMM: 1-364/364
Sequence Identity: 22% (85 aa)

IGAGGFGTVYKLCMDE---------DCVFAVKKVGRSSDGSISE-------------------------RRLEKELDVLGSIQHRNLVSLKGYCNAPTA-
|| ||||.|||              . . ||||  . .| . ..                          ..|.|. .. ...| |.|...|||..|.  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLITDFMPLGSLDEHLHERHAKDSLMTWEARLNIAIGTARGLGHLHHRCV-----PPIIHRDIKSSNVLLDRNLE------------
              ......| ||| ..||          |. |...|...|||. .|| .       |||||||.||.|.|.|.|..            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--ACVSDFGLARLL----EENDSQVTTI--------------VAGTFGYLAPEYMQ----------------SGRATEKSDVYSYGVVLLELLSGKRPTD
  ....||||.| .    . ||.. |.               . ||....||| ..                .. ..||.||||.|.|| |.|...|   
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---

VCFTAKGLNIVGWASA----MMLQNRCLEIFDPHCR---------GAQLESMEAVLEVAAMCIHPRPECRPSMATVAEIL
     ....   .  .    .|.  .|..   | .                .. . . . .| .. || |||. .. ..|
---PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAKf_g-1.AA IRAK 270-467 36 1.7e-57 197.36 In-house 7-223 (317) Show / Hide 
Range on Protein: 270-467
Range on HMM: 7-223/317
Sequence Identity: 36% (80 aa)

IGAGGFGTVYKL-CMDEDCVFAVKKVGRSSDGSI--SERRLEK---ELDVLGSIQHRNLVSLKGYCNAPTARLLITDFMPLGSLDEHLHERHAKDSL--M
|| ||||.||.  .  .. ..||||.    | |.  ...|.     || |. ...| |.|.| ||| ..    |. ..|| |||   |. . . ...   
IGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQCPPKPL

TWEARLNIAIGTARGLGHLHHRC-VPPIIHRDIKSSNVLLDRNLEACVSDFGLARLL----EENDSQV----TTIVAGTFGYLAPEYMQ--SGRATEKSD
.|  |. |..|||.|...||      ||||.||||.|.||| ....  .||||.|      .  .. .    | .| ||  |..||..   .|. | |.|
SWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQLTKKTD

VYSYGVVLLELLSGKRP
||| |.||||.|.| |.
VYSFGIVLLEVLTGCRA
Pkinase IRAKf_g-1.AA Pkinase 264-465 25 4.3e-49 174.21 Pfam 1-209 (293) Show / Hide 
Range on Protein: 264-465
Range on HMM: 1-209/293
Sequence Identity: 25% (55 aa)

LDYKDIIGAGGFGTVYKLCMDEDCV-FAVKKVGRSSDGSISERRLEK--ELDVLGSIQHRNLVSLKGYCNAPTARLLITDFMPLG----SLDEHLH-ERH
.  . .||.|.||.||| .   ..  .|||.. .... |  .... .  |. .. ...| | | |....  ..   ....... |    .| .... .||
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH

AKDSLMTWEARLNIAIGTARGLGHLHHRCVPPIIHRDIKSSNVLLDRNLEA----CVSDFGLARLLEENDSQVTTIVAGTFGYLAPEYMQ-SGRATEKSD
 . . ....   ...  ..||| ..| .    |||||.|..|.|.|.| .     ...|||||.....  .. .| ..|| .|.|||  . .   . |.|
GCFY-FSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTTFCGTPWYMAPEVIRGGQYYGPKVD

VYSYGVVLLELLSGK
..|.|..| |.|.|.
MWSCGCILYEMLCGR
Kinase IRAKf_g-1.AA TKL-Unique 266-467 30 5.7e-47 162.36 In-house 1-233 (290) Show / Hide 
Range on Protein: 266-467
Range on HMM: 1-233/290
Sequence Identity: 30% (72 aa)

YKDIIGAGGFGTVYKLCMDEDCVFAVKKVGRSSDGSISERR-LEKELDVLGSIQ-HRNLVSLKGYCN----APTARLLITDFMPLGSLDEHLH------E
    ||.||.|.|||     . | |.|.    .| | .... .|.|. ..  .. | |.| . |||     .|  . ......|.|||...||       
FWNKIGEGGYGQVYKGKWRGYPV-AIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

RHAKDSLMTWEARLNIAIGTARGLGHLHHRCVPPIIHRDIKSSNVLLDRN-----LEACVSDFGLARLLE-ENDSQVTTI-------VAGTFGYLAPEYM
  .. . .... |...||  |.|. .|||.  | |||||.||||.|.|.|     . . ..||||....  .|.. ....       . |.| ..||| .
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVL

QS--GRATEKSDVYSYGVVLLELLSGKR------P
 .     .|||||||.|.|| |....|.      |
RMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP
Kinase IRAKf_g-1.AA MLK 264-467 27 4.9e-43 147.15 In-house 1-235 (291) Show / Hide 
Range on Protein: 264-467
Range on HMM: 1-235/291
Sequence Identity: 27% (66 aa)

LDYKDIIGAGGFGTVYKLCMDEDC----VFAVKKVGRSSDGSISE-----RRLEKELDVLGSIQHRN----LVSLKGYCNAPTA-RLLITDFMPLGSLDE
.. . .||.|.|| |.|  .        . |||.|  . . ..|.     . .|.|   |  ..|.|     . ..| |. |.   .... ... ||| .
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIF-DKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HLHERHAKDS----------LMTWEARLNIAIGTARGLGHLHHRCVPPIIHRDIKSSNVLLDR------NLEACVSDFGLARLLEENDSQVTTIVAGTFG
 ||..  | .           .. .  .|.|   |||.  ||   ..||||||.||.|.|.|.      .. . ..|||..| . ... .  .  |||. 
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC-TNMMSNAGTYA

YLAPEYM---QSGRATEKSDVYSYGVVLLELLSGKRP
. |||     .... .||.||.|.|||| |.|... |
WMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP
Kinase IRAKf_g-1.AA LRRK 264-467 26 1.8e-42 147.43 In-house 1-282 (351) Show / Hide 
Range on Protein: 264-467
Range on HMM: 1-282/351
Sequence Identity: 26% (75 aa)

LDYKDIIGAGGFG-TVYKLCMDE---------------------------DCVFAVKKVGR----------SSDG----------------------SIS
| .   || |||| .||.  .                             .   |.||  |          .|..                      . .
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

ERRLEKELDVLGSIQHRNLVSLKGYCNAPTARLLITDFMPLGSLDEHLHERHAKDSL------MTWEARLNIAIGTARGLGHLHHRCVPPIIHRDIKSSN
 | . .|. .. . .| |.|||||.|  | .  ......|.|.|...||. ...|..      ..|  .| ||.  |.|...| |.. ||||||| || |
FREFRHEVWIMSHLNHPNIVSLKGFCIHPLC--MVMEYAPHGDLYHFLHN-KKQDGFHFMKAHISWMLKLKIALQIAKGMEYL-HSHNPPIIHRDLKSPN

VLL---D---------RNLEACVSDFGLARLLEENDSQ-VTTIVAGTFGYLAPEYMQSG---RATEKSDVYSYGVVLLELLSGK-RP
.||   .          .  | ..|||. |.    .   |.  . |..|..||| |. .     |||.|.||.|..| |||... .|
ILLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHP
Kinase IRAKf_g-1.AA Dicty4-Unclassified 309-467 37 1e-40 137.13 In-house 47-207 (263) Show / Hide 
Range on Protein: 309-467
Range on HMM: 47-207/263
Sequence Identity: 37% (62 aa)

KELDVLGSIQHRNLVSLKGYCNAP----TARLLITDFMPLGSLDEHLH-ERHAKDSLMTWEA--RLNIAIGTARGLGHLHHRCVPPIIHRDIKSSNVLLD
|| ..|||||| ||| ..||| .|         .. ||. | | |  |     ..  .  .    . .|.  |.|. ||| |    .|||||||||.|.|
KEVEILGSIQHPNLVKCYGYCINPRSHKSTMCIVMEFMHKGNLFEVIHSKPSEQQQPIKLDDTLIIKYAFDIAQGMQHLHTR---NFIHRDIKSSNILMD

RNLEACVSDFGLARLLEENDSQVTTIVAGTFGYLAPEYMQSGRATEKSDVYSYGVVLLELLSGKRP
..  . . |||..|  . |  .  | .|||    .|| .     . |||||||...| ||. |  |
KHFNIKIADFGISRVIDFN--FNMTTIAGTPKWESPECLMHESYNQKSDVYSYAMMLYELATGDEP
Kinase IRAKf_g-1.AA TK 264-467 15 1.6e-37 122.85 In-house 1-394 (486) Show / Hide 
Range on Protein: 264-467
Range on HMM: 1-394/486
Sequence Identity: 15% (61 aa)

LDYKDIIGAGGFG---TVYKLCMDED--------------------------CVFAVKKVGRSSDGSISERRL---------------EKELDVLGS--I
. . . .|.| ||   .|||  . ..                          .  ||| .   .. |  |...                 |. .. .   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHRNLVSLKGYCNAP------------TARLLITDFMPLGS----LDEHLHERHAKDSL-----------------------------------------
.| |.|.| |.|  .               .... .||.|.    |...|.... | .                                          
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

-------------------------------MTWEARLNIAIGTARGLGHLHHR----CVPPIIHRDIKSSNVLLDRNLE-----------ACVSDFG--
                               .| . .| ..   |.|. .|| .      . ..|||.   |.|...|.            . ..|||  
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

------LARLLEENDSQVTTIVAGTFG-------------------------YLAPEYMQ---------SGRATEKSDVYSYGVVLLELLS-GKRP
      ||| ....|  ...   || .                         ..||| ..          |. |.||||.|.||.. |... |. |
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEP
Kinase IRAKf_g-1.AA Dicty4 309-462 34 2e-37 122.49 In-house 47-211 (277) Show / Hide 
Range on Protein: 309-462
Range on HMM: 47-211/277
Sequence Identity: 34% (58 aa)

KELDVLGSIQHRNLVSLKGYCN----APTARLLITDFMPLGSLDEHLHE---RHAKDSLMTWEARLN---IAIGTARGLGHLHHRCVPPIIHRDIKSSNV
|| . ...|.| |.. ..|.|.    .|   .  | .|| |.| . ||       .   . |. ..    .|. .|||. .||  | | |||||.||.| 
KEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHC-CNPVIIHRDLKSHNL

LLDRNLEACVSDFGLAR-LLEENDSQV-TTIVAGTFGYLAPEYMQSGRATEKSDVYSYGVVLLELL
| | |. . |.||||..   .. | .  .. ..|| .. ||| |.. . .||.||||.| || |.|
LVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPYNEKADVYSFGIVLWEIL
Kinase IRAKf_g-1.AA S_TKc 264-535 21 1.8e-34 121.78 SMART 1-231 (231) Show / Hide 
Range on Protein: 264-535
Range on HMM: 1-231/231
Sequence Identity: 21% (63 aa)

LDYKDIIGAGGFGTVYKLCMDE-DCVFAVKKVGRSSDGSISERRLEKELDVLGSIQHRNLVSLKGYCNAPTARLLITDFMPL--GSLDEHLHERHA--KD
 .  ..|| |.||.|||    . . ..|.|..          .....|...| . .| |.| |....   .   .......   |.| .....|    ..
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK---------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLR

SLMTWEARLNIAIGTARGLGHLHHRCVPPIIHRDIKSSNVLLDRNLEACVSDFGLARLLEENDSQVTTIVAGTFGYLAPEYMQSGRATE-KSDVYSYGVV
. ..      ..  ....| ..| .    |||||.| .|.|||.  .  ..||||||.|        | . ||  |.||| .     .  |.|..| |..
FPFPE-HARFYMYQICCALEYCHSHG---IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCI

LLELLSGKRPTDVCFTAKGLNIVGWASAMMLQNRCLEIFDPHCRGAQLESMEAVLEVAAMCIHPRPECRPSMATVAE----------I
| |.|.|. | .                .|. ....             | ||       | .  || ||.   . .          .
LYEMLCGYPPFP--------------QMQMMFKKIG-------------SPEAKD-FIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKf_g-1.AA Pkinase_Tyr 264-467 25 2.1e-34 117.16 Pfam 1-214 (270) Show / Hide 
Range on Protein: 264-467
Range on HMM: 1-214/270
Sequence Identity: 25% (56 aa)

LDYKDIIGAGGFGTVYKLCMD-----EDCVFAVKKVGRSSDGSIS--ERRLEKELDVLGSI-QHRNLVSLKGYCNAPTAR---LLITDFMPLGSLDEHLH
.     .|.| ||.|||  ..     ...  |||.. . .  .     . . .|. .. .. .| |.|.| | |         .... .||.|.|...|.
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR

ER-HAKDSLMTWEARLNIAIGTARGLGHLHHRCVPPIIHRDIKSSNVLLDRNLEACVSDFGLARLL-EENDS-QVTTIVAGTFGYLAPEYMQSGRATEKS
.. . |..| . .  |....  |.|. .|. .    .||||.   |.|...|. . ..||||||.. ..    ....        .||| .. |. |.||
KHREDKQPLTMKD-LLQMCWQIAKGMEYLESKN---CIHRDLAARNCLVTENNVVKICDFGLARDIYNDDYYYRKRGGGKLPIKWMAPECINYGKFTTKS

DVYSYGVVLLELLS-GKRP
||.|.||.. |... |. |
DVWSFGVLMWEIFTYGEQP
Kinase IRAKf_g-1.AA TyrKc 264-536 21 5e-33 116.96 SMART 1-280 (280) Show / Hide 
Range on Protein: 264-536
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

LDYKDIIGAGGFGTVYKLCMDEDCVFAVKKVGRSSDGSISERRLEKELDVLGSI--QHRNLVSLKGYCNAP-------TARLLITDFMPLGSLDEHLHER
.  ....| | ||.|||  ..     |||..  ..     .. . .|. .. ..  .| |.| | |.|  .          .... .||.|.|...|...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA-----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKH

HAKDSLMTWEARLNIAIGTARGLGHLHHRCVPPIIHRDIKSSNVLLDRNLEACVSDFGLARLLEEN-------DSQVTT---IVA--GTFGYLAPEYMQS
. |    ...  |....  |.|  .||..   ..||||.   |.|...|. . .|||||.| ...        |  ...             .||| .. 
RPK---LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINY

GRATEKSDVYSYGVVLLELLS-GKRPTDV---CFTAKGLNIVGWASAMMLQNRCLEIFDPHCRGAQLESM------EAVLEVAAMCIHPRPECRPSMATV
|. |.||||.|.||.. |... |. |          .   ..    .   | . ... . ..     . |      ... ..  .| |  ||.||.....
GKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVI----EYVKQGYRMPQPPNDY-----P-MSFVCCPDEMYQIMKQCWHEDPEDRPTFSEI

AEIL
 |..
HECF
Kinase IRAKf_g-1.AA RIPK 270-467 25 4.4e-31 103.16 In-house 1-227 (290) Show / Hide 
Range on Protein: 270-467
Range on HMM: 1-227/290
Sequence Identity: 25% (58 aa)

IGAGGFGTVYKLCMDEDCVFAVKKVGRSSD-----GSISERRLEKELDVLGSIQHRNLVSLKGYCNAPTA------RLLITDFMPLGSLDEHLHERHA-K
.| ||||.|.|       . ..||.  .        .  .  .  |   . ...... |...| |. . .        . . .|. ||| . || .    
VGGGGFGEVFKARHRHWGDWVAKKCKPCKHCHTHMDDQERMYQKEEAKHMHKLRCEHIVPIYGFCQCEEWDCDCKLYGIVMEYMENGSLWHFLHTKWPYQ

DSLMTWEARLNIAIGTARGLGHLHHRCVPPIIHRDIKSSNVLLDRNLEACVSDFGLARLLEENDSQV----------TTIVA--GTFGYLAPEYMQ---S
.    |  |  .   ...|   ||    ||||||| | .|.|.|.|. . ..|||||  ..   |.           ..     ||  |..||      .
HHPDPWPLRCRMIHEISCGMCYLHSMN-PPIIHRDLKPENILVDNNFHVKIADFGLATWMMWSHSHQDRCNQREVYSMKSKNRWGTLSYMPPEHFRTDNK

GR---ATEKSDVYSYGVVLLELLSGKRP
 .   .|.|.||||...|. |.|..| |
KPIKVVTPKYDVYSFAIVMWEVLTQKHP
Kinase IRAKf_g-1.AA CZAK 264-467 29 9.2e-29 101.64 In-house 1-221 (279) Show / Hide 
Range on Protein: 264-467
Range on HMM: 1-221/279
Sequence Identity: 29% (66 aa)

LDYKDIIGAGGFGTVYKLCMDEDCVFAVKKVGRSSDGSISE----RRLEKELDVLGSIQHRNLVSLKGYCNAPT--ARLLITDFMPLGSLDEHLHERHAK
|     || | || |||    .  | |.|.. | .    .|       .||  ..    | | |   | | .     .  .. .|  |||.  | ..   
LKFGQTIGQGFFGEVYKAYWRGKDV-AIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHY--

DSLMTW--EARLNIAIGTARGLGHLHHRCVP-PIIHRDIKSSNVLLDRNLE-------------ACVSDFGLARLLEENDSQVTTIVAGTFGYLAPEYMQ
 ...      ..|.||  |||   ||    | ||.|||  |.|.||| ..              . ..|||| |.  |  .. |  . |   . |||   
-FYHKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPFEMTQTM-GCLCWMAPECFK

SGRATEKSDVYSYGVVLLELLSGKRP
    |||.||||.| .| ... .  |
GENYTEKVDVYSFGMILWCIITCDQP
Kinase IRAKf_g-1.AA TK 508-536 25 0.000206 9.86 In-house 447-486 (486) Show / Hide 
Range on Protein: 508-536
Range on HMM: 447-486/486
Sequence Identity: 25% (10 aa)

M-----------EAVLEVAAMCIHPRPECRPSMATVAEIL
|           |.. ..  .| |. || ||..... | |
MRYRMHPPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
Kinase IRAKf_g-1.AA Dicty4 264-280 47 0.00066 9.11 In-house 1-17 (277) Show / Hide 
Range on Protein: 264-280
Range on HMM: 1-17/277
Sequence Identity: 47% (8 aa)

LDYKDIIGAGGFGTVYK
..  ..|| |.||.|||
INIEQRIGKGSFGEVYK
Kinase IRAKf_g-1.AA MLK 517-536 30 0.002997 7.28 In-house 272-291 (291) Show / Hide 
Range on Protein: 517-536
Range on HMM: 272-291/291
Sequence Identity: 30% (6 aa)

MCIHPRPECRPSMATVAEIL
.| .. |. |||.. . ..|
QCWNQDPHKRPSFRQIVQHL
Kinase IRAKf_g-1.AA LRRK 523-538 25 0.003756 6.98 In-house 336-351 (351) Show / Hide 
Range on Protein: 523-538
Range on HMM: 336-351/351
Sequence Identity: 25% (4 aa)

PECRPSMATVAEILQE
|..||.. .. ..| .
PKKRPHFSQIVKRLSQ
Kinase IRAKf_g-1.AA Pkinase_Tyr 517-536 40 0.039954 7.82 Pfam 251-270 (270) Show / Hide 
Range on Protein: 517-536
Range on HMM: 251-270/270
Sequence Identity: 40% (8 aa)

MCIHPRPECRPSMATVAEIL
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QCWHYDPEDRPTFSEIHEQL
Kinase IRAKf_g-1.AA Dicty4 518-538 26 0.065296 2.36 In-house 255-277 (277) Show / Hide 
Range on Protein: 518-538
Range on HMM: 255-277/277
Sequence Identity: 26% (6 aa)

CIHPRPECRPSMATVAEI--LQE
| .. |. |||.. . ..  | .
CWDHDPQHRPSFEEIIQRRILEH
Kinase IRAKf_g-1.AA Dicty4-Unclassified 518-536 36 0.105196 1.57 In-house 245-263 (263) Show / Hide 
Range on Protein: 518-536
Range on HMM: 245-263/263
Sequence Identity: 36% (7 aa)

CIHPRPECRPSMATVAEIL
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CWHNDPNKRPTMNQIIQYL