Gene IRAKf_c-2 (S.moellendorffii)
IRAKf_c-2
Species: S.moellendorffii
Alias: IRAKf_c-2
External Links:
Annotation:
Sequence
| Name | Sequence Type | Origin | Length | Description | Download |
|---|---|---|---|---|---|
| IRAKf_c-2.AA | Protein | None | 927 | None | Fasta, JSON |
| IRAKf_c-2.NA | RNA | None | 2784 | None | Fasta, JSON |
| IRAKf_c-2.kin_dom | Protein Kinase Domain | None | 205 | None | Fasta, JSON |
Protein domains of IRAKf_c-2.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.
Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.
| Domain | Protein name | Domain Name | Range | Identity (%) | Significance | Score | Profile Source | Profile Range (length) | Alignment |
|---|---|---|---|---|---|---|---|---|---|
| LRRNT_2 | IRAKf_c-2.AA | LRRNT_2 | 46-86 | 41 | 1.6e-14 | 50.11 | Pfam | 1-46 (46) | Show / Hide |
Range on Protein: 46-86 Range on HMM: 1-46/46 Sequence Identity: 41% (19 aa) WNDDVLGLLVFKAGLQD-PR--GSLASWSEAD--SSPCNWTGIRCG |||.. || ||..|.| .. |.|.||. . |..|.|||. | HNDDGQALLAFKSSLNDSDPHHGVLSSWNPSSSDSDCCSWTGVTCD |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 115-138 | 40 | 0.034737 | 11.92 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 115-138 Range on HMM: 1-26/26 Sequence Identity: 40% (11 aa) RLKTLSLSA-N--NLSGNVVPELFRML .|..|.|| | ||.|.. |. | | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_TYP | IRAKf_c-2.AA | LRR_TYP | 113-137 | 34 | 0.106902 | 7.81 | SMART | 1-24 (24) | Show / Hide |
Range on Protein: 113-137 Range on HMM: 1-24/24 Sequence Identity: 34% (9 aa) LERLKTLSLSANNLSGNVVP-ELFRM | |..|.|| |.| .| ..|. LPNLRELDLSNNQL--THLPPGAFQG |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 91-113 | 22 | 75.613317 | 0.08 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 91-113 Range on HMM: 1-26/26 Sequence Identity: 22% (6 aa) RVESVSLDG-L--ALSGTIGRG-LLKL . .. .|.| |.|.| . . .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 159-182 | 25 | 1.310059 | 6.33 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 159-182 Range on HMM: 1-26/26 Sequence Identity: 25% (7 aa) SIRYVDLSD-N--AFTGALARDFFGGG .... |||. | .|| . . | . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 184-206 | 37 | 0.008655 | 14.06 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 184-206 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) LLRYLSLSK-N--RLTGQLSPS-LAAN |..|.|| | .|||...|| . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 258-280 | 44 | 0.00025 | 19.52 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 258-280 Range on HMM: 1-26/26 Sequence Identity: 44% (12 aa) SLRSLNLAG-N--NLTGVVPQS-LLQL .|..|.| | | |||| .| | . .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 234-256 | 44 | 0.000544 | 18.32 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 234-256 Range on HMM: 1-26/26 Sequence Identity: 44% (12 aa) ALQELDFSW-N--GFQGSIPPS-LATL ||.||.| | ..|.|||| . | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_TYP | IRAKf_c-2.AA | LRR_TYP | 256-279 | 37 | 0.012143 | 15.55 | SMART | 1-24 (24) | Show / Hide |
Range on Protein: 256-279 Range on HMM: 1-24/24 Sequence Identity: 37% (9 aa) LSSLRSLNLAGNNLTGVVPQSLLQ |..||.|.| .|.|| . |. . LPNLRELDLSNNQLTHLPPGAFQG |
|||||||||
| LRR_TYP | IRAKf_c-2.AA | LRR_TYP | 280-304 | 44 | 0.036746 | 11.61 | SMART | 1-24 (24) | Show / Hide |
Range on Protein: 280-304 Range on HMM: 1-24/24 Sequence Identity: 44% (11 aa) LLRLSSLDLSSNHLGGKIPFGLFSS | | .||||.|.| .| |.|.. LPNLRELDLSNNQL-THLPPGAFQG |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 305-326 | 29 | 0.04276 | 11.6 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 305-326 Range on HMM: 1-26/26 Sequence Identity: 29% (8 aa) SLQFLNLSR-N--EFLGDFPI--WPPC .|| |.||. | . |..| . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 282-304 | 37 | 0.077714 | 10.68 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 282-304 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) RLSSLDLSS-N--HLGGKIPFG-LFSS .| .||||. | .| |.|| . . . NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_TYP | IRAKf_c-2.AA | LRR_TYP | 232-255 | 36 | 0.930168 | 0.11 | SMART | 1-24 (24) | Show / Hide |
Range on Protein: 232-255 Range on HMM: 1-24/24 Sequence Identity: 36% (9 aa) LRALQELDFSWNGFQGSIPPSL-AT |..|.||| |.| . ..|| . . LPNLRELDLSNNQL-THLPPGAFQG |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 209-232 | 22 | 1.219747 | 6.44 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 209-232 Range on HMM: 1-26/26 Sequence Identity: 22% (6 aa) GLVTLRIAE-N--GFSGDLPDWIGKSL | .| . | ..|..|... .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 328-350 | 29 | 0.00731 | 14.32 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 328-350 Range on HMM: 1-26/26 Sequence Identity: 29% (8 aa) ALQVVDISG-N--RIFGEVPSR-IAQC ||. |.|| | .. |..|.. . .. NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 376-398 | 44 | 0.000409 | 18.76 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 376-398 Range on HMM: 1-26/26 Sequence Identity: 44% (12 aa) RLMFLDLSH-N--QLQGGIPST-FTNM .| ||||. | .|.| ||. | |. NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 352-374 | 37 | 0.051957 | 11.3 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 352-374 Range on HMM: 1-26/26 Sequence Identity: 37% (10 aa) SLQHLNVGW-N--VLSGGIPGQ-ISQL .||||... | |.| || . .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 400-422 | 29 | 0.07426 | 10.75 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 400-422 Range on HMM: 1-26/26 Sequence Identity: 29% (8 aa) SLTVLKLAK-N--LLVGNIPKA-ISKC .|..| | | |.|.||. . .. NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_TYP | IRAKf_c-2.AA | LRR_TYP | 374-397 | 45 | 0.10964 | 7.72 | SMART | 1-24 (24) | Show / Hide |
Range on Protein: 374-397 Range on HMM: 1-24/24 Sequence Identity: 45% (11 aa) LQRLMFLDLSHNQLQGGIPSTFTN | | ||||.|||. | .| . LPNLRELDLSNNQLTHLPPGAFQG |
|||||||||
| LRR_TYP | IRAKf_c-2.AA | LRR_TYP | 398-422 | 24 | 0.439355 | 2.78 | SMART | 1-24 (24) | Show / Hide |
Range on Protein: 398-422 Range on HMM: 1-24/24 Sequence Identity: 24% (6 aa) MSSLTVLKLAKNLLVGNIPKAISKC ...|..| | | | .| . . LPNLRELDLSNNQL-THLPPGAFQG |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 424-446 | 40 | 0.000125 | 20.59 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 424-446 Range on HMM: 1-26/26 Sequence Identity: 40% (11 aa) RLVELDLSS-N--RLSGSIPGA-LSRL .| .||||. | .|.|.|| . | NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 448-470 | 48 | 0.000577 | 18.23 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 448-470 Range on HMM: 1-26/26 Sequence Identity: 48% (13 aa) FLQSLDLAW-N--NLTGPIPKE-LVKL ||.||| | |||| ||.. . .| NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_1 | IRAKf_c-2.AA | LRR_1 | 472-495 | 40 | 0.040595 | 11.68 | Pfam | 1-26 (26) | Show / Hide |
Range on Protein: 472-495 Range on HMM: 1-26/26 Sequence Identity: 40% (11 aa) SLSSLDVSH-N--HLDGPIPKGGVFNL .| .||.|. | .| | ||.. || NLQHLDLSGCNCCNLTGHIPPSCF-NL |
|||||||||
| LRR_TYP | IRAKf_c-2.AA | LRR_TYP | 470-495 | 38 | 0.188585 | 5.79 | SMART | 1-24 (24) | Show / Hide |
Range on Protein: 470-495 Range on HMM: 1-24/24 Sequence Identity: 38% (10 aa) LESLSSLDVSHNHLDGPIPKGGVFNL | .| .|| |.|.| .| |.|. LPNLRELDLSNNQL-THLP-PGAFQG |
|||||||||
| Kinase | IRAKf_c-2.AA | TKL | 640-906 | 21 | 8.1e-55 | 188.44 | In-house | 1-364 (364) | Show / Hide |
Range on Protein: 640-906
Range on HMM: 1-364/364
Sequence Identity: 21% (81 aa)
IGRGGFGVVYRAAISD---------GRTFAVKKLVTAGLVKSQL-------------------------EFEKEVQ-QLGKIEHPNLVALQGYYWTSRM-
||.||||.||.. |.. ||||. . .. . .||.|. .. .. |||.| . || ..
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG
------------QLLIYDFVPNGSLYSRLHERTFGEPPLSWSERFKIAQGTAMGLSHLHHSC-----QPQVIHYDLKSNNILLGVDNR------------
......|.|||...|| |. |...|...| |...|| . |..|| ||||.|||. ...
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH----------WHQRCRWALDIARGMNYLHSMNPKWCTKPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD
--PLISDYGLANLLPVL-----------------DRYAISSKFQGALGYMAPEFASQS---------------SKVTEKCDVYGFGIILLELVTGRRPVE
. |.|.||. . .. ... | ...|||| .. .. .|||||| |||.| |..|..|| .
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCRPYY
-YMEEDVVIL---CDYVRALLNEGRGMSC------VEPSLEASPEDEVLP-VIKLGLICSSPLPSNRPSMAEVVQIL
|....... .. ..|. . .. .|.. ..| ..|| | .. |..|||. |....|
DYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHH-K-M-CPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
|
|||||||||
| Kinase | IRAKf_c-2.AA | IRAK | 635-839 | 37 | 9.6e-47 | 161.61 | In-house | 2-224 (317) | Show / Hide |
Range on Protein: 635-839 Range on HMM: 2-224/317 Sequence Identity: 37% (83 aa) NKEQEIGRGGFGVVYRAAISDGR-TFAVKKL---VTAGLVKSQLEFEK---EVQQLGKIEHPNLVALQGYYWTSRMQLLIYDFVPNGSLYSRLHERTFGE .|. || ||||.|||. .. ..||||| . .. .| |.... .. |||.|.| || . |.|.. ||||| ||. .. HKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQC PP--LSWSERFKIAQGTAMGLSHLHHSCQPQ--VIHYDLKSNNILLGVDNRPLISDYGLANLL---PVLDRYAI----SSKFQGALGYMAPEFAS-QSSK || ||| |..|..||| |. .| |. .| .|| | || |||| . | |.| ||. ... . . |...| . ||.||| . . PPKPLSWHQRCSICWGTACGIQFL-HQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ VTEKCDVYGFGIILLELVTGRRPV | | ||| ||| |||..||.|.| LTKKTDVYSFGIVLLEVLTGCRAV |
|||||||||
| Kinase | IRAKf_c-2.AA | LRRK | 634-840 | 26 | 1.3e-32 | 112.67 | In-house | 1-284 (351) | Show / Hide |
Range on Protein: 634-840 Range on HMM: 1-284/351 Sequence Identity: 26% (75 aa) LNKEQEIGRGGFG-VVYRAAISD---------------------------GRTFAVKKLVT---------------------------------AGLVKS | .|..||||||| .|||| . . . |.||. . ... .. LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA QLEFEKEVQQLGKIEHPNLVALQGYYWTSRMQLLIYDFVPNGSLYSRLHERTFGE-----PPLSWSERFKIAQGTAMGLSHLHHSCQPQVIHYDLKSNNI || .|| . . .|||.| | |. .. .. ...|.|.||..||.. . . .||. . ||| | |. .| ||. | .|| |||| || FREFRHEVWIMSHLNHPNIVSLKGFCIHPLC--MVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYL-HSHNPPIIHRDLKSPNI LLGVDNRPL------------ISDYGLANLLPVLDRYAISSKFQGALGYMAPEFASQS--SKVTEKCDVYGFGIILLELVTGR-RPVE || . . |.|.|. . ..... ... | |.|||| . ||| |.| ||.|| ||.|.. .| . LLWSSPQNHSPNYPNAHVCAKIADFGISRMF-QCFHMGVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFD |
|||||||||
| Kinase | IRAKf_c-2.AA | MLK | 634-838 | 24 | 2.6e-31 | 105.93 | In-house | 1-235 (291) | Show / Hide |
Range on Protein: 634-838 Range on HMM: 1-235/291 Sequence Identity: 24% (59 aa) LNKEQEIGRGGFGVVYRAAISDGR----TFAVKKLVTAG--LVKS---QLEFEKEVQQLGKIEHPN--LVALQGYYWTSRM-Q--LLIYDFVPNGSLYSR .. .. || |.||.|... . . |||. . ... | .||.|. .| .. ||| | |. .. . ... ....||||. IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV LHERT-------FGEP---PLSWSERFKIAQGTAMGLSHLHHSCQPQVIHYDLKSNNILLGV------DNRPLISDYGLANLLPVLDRYAI---SSKFQG ||... ... . . ...| | |.. || ....||.|||| |||. . |.| |.. | . . ...| LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPKPIIHRDLKSHNILIDEICHDMHHGTLKICDFGTS-----RDWHQMCTNMMSNAG ALGYMAPEFA--SQSSKVTEKCDVYGFGIILLELVTGRRP . .|||| ....|..|||||. .|..| |..|.. | TYAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTREVP |
|||||||||
| Kinase | IRAKf_c-2.AA | TKL-Unique | 638-838 | 28 | 4.5e-31 | 106.91 | In-house | 3-233 (290) | Show / Hide |
Range on Protein: 638-838 Range on HMM: 3-233/290 Sequence Identity: 28% (67 aa) QEIGRGGFGVVYRAAISDGRTFAVKKLVT-AGLVKSQLE-FEKEVQQLGKIE-HPNLVALQGYYW----TSRMQLLIYDFVPNGSLYSRLH--------- ||.||.|.||. .. | |.|.. ... .. .. ||.|| . |.. |||.| . || . .. ...| ||||. || NKIGEGGYGQVYK-GKWRGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN ERTFGEPPLSWSERFKIAQGTAMGLSHLHHSCQPQVIHYDLKSNNILLGVD-----NRPLISDYGLANLLPVLDRYAIS-------SKFQGALGYMAPEF .. .|... | |.|. | |. .|||. | .|| |||| |.|. . .. |.| ||. .. .. .. . ..| . .|||| NNNC---KLNMQQRVKMAIDIAQGMYYLHHCEPP-IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV ASQS-SKVTEKCDVYGFGIILLELVTGRR------P ... .. .||.||| |||.| |..|. . | LRMNFCQYSEKSDVYSFGIVLWEIATRKITKTYKKP |
|||||||||
| Kinase | IRAKf_c-2.AA | Pkinase | 634-836 | 24 | 1.3e-30 | 109.38 | Pfam | 1-209 (293) | Show / Hide |
Range on Protein: 634-836 Range on HMM: 1-209/293 Sequence Identity: 24% (53 aa) LNKEQEIGRGGFGVVYRA-AISDGRTFAVKKLVTAGLVKSQLEFEK---EVQQLGKIEHPNLVALQGYYWTSRMQLLIYDFVPNG----SLYSRLH--ER . ... ||.|.||.||.. ...|...|||.. . ..... |.| . .. ||| | | ... ... .. .....| .|..... .. YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWRH TFGEPPL--SWSERFKIAQGTAMGLSHLHHSCQPQVIHYDLKSNNILLGVDNRP----LISDYGLANLLPVLDRYAISSKFQGALGYMAPEFASQSSKVT . .. |. | ... .. || ..| .|| |||. |||. .. . |.| ||| .. . .. . | | ..||||| ... . G----CFYFSEWECKFYMYQILRGLEYCHSM---GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYG EKCDVYGFGIILLELVTGR |.|....|.|| |...|| PKVDMWSCGCILYEMLCGR |
|||||||||
| Kinase | IRAKf_c-2.AA | S_TKc | 634-909 | 21 | 2.4e-28 | 101.44 | SMART | 1-231 (231) | Show / Hide |
Range on Protein: 634-909 Range on HMM: 1-231/231 Sequence Identity: 21% (62 aa) LNKEQEIGRGGFGVVYRAAISD-GRTFAVKKLVTAGLVKSQLEFEKEVQQLGKIEHPNLVALQGYYWTSRMQLLIYDFVPN--GSLYSRLHERTFGEPP- . ..||.|.||.||.. . || .|.|.. ...|.| | | |||.| | ... . .. ..... |.|......| . .. YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK--------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRF -LSWSERFKIAQGTAMGLSHLHHSCQPQVIHYDLKSNNILLGVDNRPLISDYGLANLLPVLDRYAISSKFQGALGYMAPEFASQSSKVTE-KCDVYGFGI .. . .... .. .| ..| . ..|| ||| |||| . |.| ||| .| . | | . ||||| . . |||.. .|. PFPE-HARFYMYQICCALEYCH--SH-GIIHRDLKPENILLDE--HIKICDFGLARQL---------TTFCGTPWYMAPEVL----GYGKCKCDWWSCGC ILLELVTGRRPVEYMEEDVVILCDYVRALLNEGRGMSCVEPSLEASPEDEVLPVIKLGLICSSPLPSNRPSMAEVVQ------ILELV || |...|. | . .. . . .. ... . | |..||. |. | . . . ILYEMLCGYPPFP----QMQMMFKKIG-----------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF |
|||||||||
| Kinase | IRAKf_c-2.AA | TK | 634-906 | 13 | 2.9e-25 | 80.98 | In-house | 1-486 (486) | Show / Hide |
Range on Protein: 634-906
Range on HMM: 1-486/486
Sequence Identity: 13% (68 aa)
LNKEQEIGRGGFG---VVYRAAISDGR--------------------------TFAVKKLV--TAGLVKSQLE--------------FEKEVQQLG--KI
. ....|.| || .||.. ... . ||| | .| . ... . | ... .
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG
EHPNLVALQG-------------YYWTSRMQLLIYDFVPNGS----LYSRLH--ERTFGEPP--------------------------------------
.|||.| | | . .. ... ..|.|. | . |. ..| ...
HHPNIVRLYGVCTQGEPKPCFEVV-VHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQD
--------------------------------LSWSERFKIAQGTAMGLSHLHHS----CQPQVIHYDLKSNNILLGVDNR-----------PLISDYGL
|. .. ... | |...|| ....| || |.|.| .|. |.|.||
YDDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCEFI-QNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGL
AN-----LLPVLDR--YAISSKFQGALG-------------------------YMAPEFASQSS--------KVTEKCDVYGFGIILLELVT-G-RRPVE
. | ... . ... .|. . .|||| | |.| ||. ||. . |..| | . .
SRQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFTYGQEPYYG
YMEEDVVIL---CDYVRALLNE------------GRGMSCVEP---------SLEASPEDEVLPVIKL-GLICSSPLPSNRPSMAEVVQIL
.| . |. .. | .| . |..| . | . |. . ... . . | .. |. ||....... |
GMSNQDVWKDGDNQEVMEYLRRGGRLCRSGLNEVGYRMRMPQPPHCPDWMRYRM-H-PPHCPPEEYYDLMQQCWHYDPEDRPTFSQLHEQL
|
|||||||||
| Kinase | IRAKf_c-2.AA | STE | 634-838 | 20 | 1.1e-23 | 80.62 | In-house | 1-267 (359) | Show / Hide |
Range on Protein: 634-838
Range on HMM: 1-267/359
Sequence Identity: 20% (57 aa)
LNKEQEIGRGGFGVVYRAAISD----------------GRTFAVKKLVTAGL----------------VKSQLEFEKEVQQLGKIE--HPNLVALQGYYW
. . ..||.|.||.||.|. . |. .|.|.. . . ...||.. . | ||| | |.|
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF
TSR-------MQLLIYDFVPNGSLYSRLHER-TFGEP---------PLSWSERFKIAQGTAMG-LSHLHHSCQPQVIHYDLKSNNILLGVDNRPLISDYG
.. ....||| . .... |.| ... |. .|.. . | |..|| .|| |.|. |||| ..| |
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH---IIHRDIKPANILL-----VKLCDFG
LAN-LLPVLD------------RYA-ISSKFQGALGYMAPEFASQ-----SSKVTEKCDVYGFGIILLELVTGRRP
.. | . .. . . | | .|||| .| ... ..|||.. .|. ..|..||. |
VCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKPP
|
|||||||||
| Kinase | IRAKf_c-2.AA | Ciliate-E2 | 634-838 | 17 | 2.9e-23 | 76.7 | In-house | 1-295 (365) | Show / Hide |
Range on Protein: 634-838 Range on HMM: 1-295/365 Sequence Identity: 17% (52 aa) LNKEQEIGRGGFGVVYRA-AISDGRTF------------------AVKKLVTAGLVKSQLEFE-KEVQQLGKIE----------------HPNLVALQGY .. . ||.|.||.||.. ..... | ..|. . |.|.|. .| ... .|. |||.. . . YKFIKKIGQGNFGSVYKCKVWKVQKQFAIKIIDQKQQRQQMQEKVKIKIYAMKIMKKNQIEQIKQEIHIMREINCFYKKINEKNILEQLNHPNIIKMYEC YW--TSRMQLLIYDFVPNGSLYSRLHER---TFGEPP----LSWSERFKIAQGTA---------------MGLSHLHHSCQPQVIHYDLKSNNILLGVDN . . |. ... |.|.... .. . |.. ... |. .| . . .| .|| .|| |.| .|||. FQEKDDNNIYLVMEYCQGGDLFDYIKNNKKKRNHEIEKDKYFTEKEIKYIMKQILQGFKTKAEFYIACIILALEYLHSKNN--IIHRDIKPENILF---- RPLISDYGLA-NLLPVLDRYAISSKFQG-----------------------------ALGYMAPEFASQSSK--------VTEKCDVYGFGIILLELVTG . |.| ||. .. . ... . . .. .|||||| . . ..|||.. .|.|| |...| -IKIIDFGLSKKYDDDNQNRTH-KQQCKWYMFKNDTSRTPGYMDQIIQQNMFNTICGTPGYMAPEILNGKKYDNQQKQKGYDYKCDIWSLGVILYEMLFG RRP ..| KPP |
|||||||||
| Kinase | IRAKf_c-2.AA | HH498 | 705-838 | 26 | 1.4e-22 | 68.04 | In-house | 79-225 (284) | Show / Hide |
Range on Protein: 705-838 Range on HMM: 79-225/284 Sequence Identity: 26% (39 aa) LLIYDFVPNGSLYSRL--------------HERTFGEPPLSWSERFKIAQGTAMGLSHLHHSCQPQVIHYDLKSNNILLGVDNRPLISDYGLANLLPVLD ... ... ||||.|.| |. . .. . |. | | || | ....|| || | |||. | . . |.| . .. AIVTQYCDNGSLFSILNTIPIGGAGANNNNHNQKNNYRIMDLQSKMTISVDVAHGMNYLHNSLKHPIIHRDLNSHNILIHEDGHAVVADFGESRFVCDMH RYAISSKFQGALGYMAPEFASQSSKVTEKCDVYGFGIILLELVTGRRP . . | | .|||| ||. | ..| ||....... |. |.. | DDNMTKQP-GNLRWMAPEVFSQCQKYSIKVDVFSYAMCIWEMHTREVP |
|||||||||
| Kinase | IRAKf_c-2.AA | Dicty4 | 634-838 | 33 | 1.1e-21 | 69.19 | In-house | 1-216 (277) | Show / Hide |
Range on Protein: 634-838 Range on HMM: 1-216/277 Sequence Identity: 33% (74 aa) LNKEQEIGRGGFGVVYRAAISDGRTFAVKKL--VTAGLVKSQL-EFEKEVQQLGKIEHPNLVALQGYYW----TSRMQLLIYDFVPNGSLYSRLHE---R .|.||.||.|.|| ||. .. | ||||| .. . | || ||| ..|| |||.. . |. .. . ..| |.||| || INIEQRIGKGSFGEVYK-GTWRGKEVAVKKLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLLHDKPSE TFGEPPLSWSERFK---IAQGTAMGLSHLHHSCQPQVIHYDLKSNNILLGVDNRPLISDYGLAN-LLPVLDRYAISSKFQGALGYMAPEFASQSSKVTEK . .|.|. . . .| .| |. .| |.| | .|| |||| |.| ..| ..| ||. .. | . . | ..|||| .. .|| QQQSIKLDWPLIKRAMRMAFDAARGMNWL-HCCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVM-MHQPYNEK CDVYGFGIILLELVTGRRP ||| |||.| |..|. | ADVYSFGIVLWEILTRQEP |
|||||||||
| Kinase | IRAKf_c-2.AA | TyrKc | 634-906 | 23 | 3.1e-19 | 71.15 | SMART | 1-280 (280) | Show / Hide |
Range on Protein: 634-906 Range on HMM: 1-280/280 Sequence Identity: 23% (71 aa) LNKEQEIGRGGFGVVYRAAISDGRTFAVKKLVTAGLVKSQLEFEKEVQQLGKI--EHPNLVALQGYYWTS-------RMQLLIYDFVPNGSLYSRL--HE . .....|.| ||.||.. . .. |||.| . .| .| . . |. .|||.|.| |. .. ... ..|.|.| ..| |. ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA----REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHR RTFGEPPLSWSERFKIAQGTAMGLSHLHHSCQPQVIHYDLKSNNILLGVDNRPLISDYGLANLLPVL-------DRYAI----SSKFQGALGYMAPEFAS .. |.... ... | | ..||. ..|| || |.|.| ... ||| ||. . | | ..|. . |||| PK-----LCMKDLLSFCWQIACGMEYLHSK---NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECI- QSSKVTEKCDVYGFGIILLELVT-GRRPVEYMEEDVVILCDYVRALLNEGRGMSCVEP-----SLEASPEDEVLPVIKLGLICSSPLPSNRPSMAEVVQI . .| |.| ||. ||. . |. | | | . |.. .. . |.... .|. | . . . ||. ..| | |..||...|.... NYGKFTTKSDVWSFGVCMWEIFTYGQQPYPGMIQQ-MMSNQEVIEYVKQGYRMPQPPNDYPMSF--VCCPDEMYQIMKQ---CWHEDPEDRPTFSEIHEC L . F |
|||||||||
| Kinase | IRAKf_c-2.AA | Pkinase_Tyr | 634-750 | 22 | 1.9e-16 | 56.29 | Pfam | 1-128 (270) | Show / Hide |
Range on Protein: 634-750 Range on HMM: 1-128/270 Sequence Identity: 22% (29 aa) LNKEQEIGRGGFGVVYRAAIS-----DGRTFAVKKLVTAGLVKSQ---LEFEKEVQQLGKI-EHPNLVALQGYYW-TSRM--QLLIYDFVPNGSLYSRLH . . ...|.| ||.||.. .. . |||.| | ..| .| .|.. . .. |||.| | | .. ... ..|.|.|.. |. ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKML-KEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLR ERTFGEPPLSWSERFKIAQGTAMGLSHLH .. ...||. .. .... |.|...|. KHREDKQPLTMKDLLQMCWQIAKGMEYLE |
|||||||||
| Kinase | IRAKf_c-2.AA | Dicty4 | 893-908 | 44 | 1.5e-05 | 14.63 | In-house | 260-277 (277) | Show / Hide |
Range on Protein: 893-908 Range on HMM: 260-277/277 Sequence Identity: 44% (8 aa) PSNRPSMAEVVQI--LEL |..|||..|..|. || PQHRPSFEEIIQRRILEH |
|||||||||
| Kinase | IRAKf_c-2.AA | MLK | 887-906 | 40 | 0.000179 | 11.58 | In-house | 272-291 (291) | Show / Hide |
Range on Protein: 887-906 Range on HMM: 272-291/291 Sequence Identity: 40% (8 aa) ICSSPLPSNRPSMAEVVQIL .| .. |..|||....||.| QCWNQDPHKRPSFRQIVQHL |
|||||||||
| Kinase | IRAKf_c-2.AA | HH498 | 887-906 | 45 | 0.0002 | 9.5 | In-house | 265-284 (284) | Show / Hide |
Range on Protein: 887-906 Range on HMM: 265-284/284 Sequence Identity: 45% (9 aa) ICSSPLPSNRPSMAEVVQIL .| .| |.|||. ...| || MCWHPCPENRPDFDQIVTIL |
|||||||||
| Kinase | IRAKf_c-2.AA | LRRK | 893-908 | 31 | 0.010157 | 5.43 | In-house | 336-351 (351) | Show / Hide |
Range on Protein: 893-908 Range on HMM: 336-351/351 Sequence Identity: 31% (5 aa) PSNRPSMAEVVQILEL | .||.. ..|..|. PKKRPHFSQIVKRLSQ |
|||||||||
| Kinase | IRAKf_c-2.AA | Pkinase_Tyr | 893-906 | 35 | 0.140542 | 5.97 | Pfam | 257-270 (270) | Show / Hide |
Range on Protein: 893-906 Range on HMM: 257-270/270 Sequence Identity: 35% (5 aa) PSNRPSMAEVVQIL |..||...|....| PEDRPTFSEIHEQL |
|||||||||
| Kinase | IRAKf_c-2.AA | TKL-Unique | 888-906 | 42 | 0.172585 | 1.24 | In-house | 272-290 (290) | Show / Hide |
Range on Protein: 888-906 Range on HMM: 272-290/290 Sequence Identity: 42% (8 aa) CSSPLPSNRPSMAEVVQIL | . ||.||| |.. | CWHHDPSQRPSFDEIIHRL |
|||||||||
| Kinase | IRAKf_c-2.AA | IRAK | 895-906 | 50 | 0.188499 | 1.11 | In-house | 306-317 (317) | Show / Hide |
Range on Protein: 895-906 Range on HMM: 306-317/317 Sequence Identity: 50% (6 aa) NRPSMAEVVQIL .|..||.|.| | RRCDMAWVMQQL |
|||||||||
| Kinase | IRAKf_c-2.AA | Pkinase_Tyr | 805-838 | 40 | 1.18025 | 2.84 | Pfam | 181-214 (270) | Show / Hide |
Range on Protein: 805-838 Range on HMM: 181-214/270 Sequence Identity: 40% (14 aa) MAPEFASQSSKVTEKCDVYGFGIILLELVT-GRRP |||| . . |.| ||. ||. . |..| |. | MAPECINYGK-FTTKSDVWSFGVLMWEIFTYGEQP |
|||||||||