Gene IRAKb_c-1 (S.moellendorffii)

IRAKb_c-1

Species: S.moellendorffii
Alias: IRAKb_c-1
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKb

Sequence

Name Sequence Type Origin Length Description Download
IRAKb_c-1.AA Protein None 573 None Fasta, JSON
IRAKb_c-1.NA RNA None 1722 None Fasta, JSON
IRAKb_c-1.kin_dom Protein Kinase Domain None 203 None Fasta, JSON

Protein domain

Protein domains of IRAKb_c-1.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAKb_c-1.AA TKL 304-569 21 2.6e-59 203.34 In-house 1-364 (364) Show / Hide 
Range on Protein: 304-569
Range on HMM: 1-364/364
Sequence Identity: 21% (84 aa)

VAEGGFGFVYKGVLSD---------GQLVAVKQHKLASRQGDRE-------------------------FKAEVEVLSSAQ--HRNLVTLIGYCTEGGR-
. .|||| ||||..           |. ||||. |  . . . .                         |. |.|...  .  | |.| ..|||....  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RILVYEFVCNGS-LNKHLSRKNPKPLDWPSRQNIALGAARGLRYLHE----ECRIG-CIVHRDVRPNNILVTHDFT------------
              .|.|.. .|| |. ..         |. | ..||..|||. |||      |.    |.|||  ..||||  ..|            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--ALVGDFGLARWQ----ARGDTA--------------EQTRVIGTIGYVAPEYAE----------------TGQITEKADVYSFGLVLLEIITGRPAFD
  . ..||||.|.        ||.                 ...||... |||  .                 .. .||.||||||.|| ||.|...   
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---

SYQQPGQQHLPDWATPFLAARAAHELLD----ERIDESSVDEYE-LIN------------------MVTAASLCIQKDPSKRPKMTQVCSSL
               |.       ...     | .   ... .  .|                   |   .  | . ||.||| .... . |
---------------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAKb_c-1.AA IRAK 298-498 37 4.3e-59 202.64 In-house 1-223 (317) Show / Hide 
Range on Protein: 298-498
Range on HMM: 1-223/317
Sequence Identity: 37% (83 aa)

FSKENLVAEGGFGFVYKGVLSDGQ-LVAVK----QHKLASRQGDREFKA---EVEVLSSAQHRNLVTLIGYCTEGGRRILVYEFVCNGSLNKHLS-RKN-
|.|.|.  ||||| ||.|...     .|||      ..   . ...| .   |..|... .| |.| | |||||..   |||..  ||||   |. ... 
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

--PKPLDWPSRQNIALGAARGLRYLHEECRIGCIVHRDVRPNNILVTHDFTALVGDFGLARWQ--ARGDTAEQT------RVIGTIGYVAPEYAE--TGQ
  |||| |. |  |..|.|.|...||.      | |.|. . |||   .||.  .||||.|    | .  .         .|.||  | .||.    .||
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

ITEKADVYSFGLVLLEIITGRPA
.| | ||||||.||||..||..|
LTKKTDVYSFGIVLLEVLTGCRA
Kinase IRAKb_c-1.AA TKL-Unique 302-495 30 6.3e-41 142.09 In-house 3-224 (290) Show / Hide 
Range on Protein: 302-495
Range on HMM: 3-224/290
Sequence Identity: 30% (68 aa)

NLVAEGGFGFVYKGVLSDGQLVAVKQHK-LASRQGD--REFKAEVEVLSSAQ-HRNLVTLIGYCT----EGGRRILVYEFVCNGSLNKHLSR--------
|.. |||.| ||||.   |  ||.|| . ...   .  .||. || ...  . | |.|...|||.      .....| |..  |||...|..        
NKIGEGGYGQVYKGKW-RGYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNNNN

KNPKPLDWPSRQNIALGAARGLRYLHEECRIGCIVHRDVRPNNILVTHD-----FTALVGDFGLARWQARGDTAEQTRV--------IGTIGYVAPEYAE
.| ..|..  | ..|. .|.|. ||| .     | ||| .. |.||. .     . . . ||||.. ... ..   ..         .|.. ..|||  .
NNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP--IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEVLR

T--GQITEKADVYSFGLVLLEIITG
    |..||.|||||| || ||.|.
MNFCQYSEKSDVYSFGIVLWEIATR
Kinase IRAKb_c-1.AA S_TKc 298-571 22 4e-39 137.21 SMART 1-231 (231) Show / Hide 
Range on Protein: 298-571
Range on HMM: 1-231/231
Sequence Identity: 22% (64 aa)

FSKENLVAEGGFGFVYKGVLSD-GQLVAVKQHKLASRQGDREFKAEVEVLSSAQHRNLVTLIGYCTEGGRRILVYEFVCN--GSLNKHLSRKNP----KP
. . ... .|.|| |||..  . |..||.|. |       . .. |...|.. .| |.|.|.... . ..  .| |.. .  |.| ... ....    .|
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LDWPSRQNIALGAARGLRYLHEECRIGCIVHRDVRPNNILVTHDFTALVGDFGLARWQARGDTAEQTRVIGTIGYVAPEYAETGQITE-KADVYSFGLVL
..    . ..   ...| |.|.      |.|||. | |||...  .  ..||||||          | ..||  |.|||     . .  |.|..|.| .|
FPE-HARFYMYQICCALEYCHSHG----IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LEIITGRPAFDSYQQPGQQHLPDWATPFLAARAAHELLDERIDESSVDEYELINMVTAASLCIQKDPSKRPKMTQVCS-------SLAV
 | ..|.| |.              ....  .                  |.....   . | ||||.|||   ..            .
YEMLCGYPPFP--------------QMQMMFKKIG-------------SPEAKDFI---RKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKb_c-1.AA Dicty4 298-495 34 7.3e-37 120.58 In-house 1-213 (277) Show / Hide 
Range on Protein: 298-495
Range on HMM: 1-213/277
Sequence Identity: 34% (75 aa)

FSKENLVAEGGFGFVYKGVLSDGQLVAVKQHKLASRQGD------REFKAEVEVLSSAQHRNLVTLIGYCT----EGGRRILVYEFVCNGSLNKHLSRK-
  .|..  .|.|| ||||    |. ||||  || ... .       ||..||. ... .| |.... |.||    . |.   | |..  |.| . | .. 
INIEQRIGKGSFGEVYKGTWR-GKEVAVK--KLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNLYSLL-HDK

-----NPKPLDWPSRQN---IALGAARGLRYLHEECRIGCIVHRDVRPNNILVTHDFTALVGDFGLAR-WQARGDTAE-QTRVIGTIGYVAPEYAETGQI
       ..|||| .     .|. ||||. .||  |..  |.|||  . |.||  .... |.||||..  .   |    |. ..|| ...|||       
PSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLH--CCNPVIIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQPY

TEKADVYSFGLVLLEIITG
.|||||||||.|| || |.
NEKADVYSFGIVLWEILTR
Kinase IRAKb_c-1.AA TK 298-494 16 2.3e-36 118.89 In-house 1-389 (486) Show / Hide 
Range on Protein: 298-494
Range on HMM: 1-389/486
Sequence Identity: 16% (66 aa)

FSKENLVAEGGFG---FVYKGVLSDG--------------------------QLVAVKQHKLASRQGDREFKA-----------------EVEVLSS--A
   ..   || ||    |||| . ..                          . ||||. |. . . ..||..                 | .....   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHRNLVTLIGYCTEG------------GRRILVYEFVCNGS----LNKHLSRKNPK--------------------------------------------
.| |.| |.|.||.|            .  ..| |....|.    | ..| .. ||                                            
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

------------------------------PLDWPSRQNIALGAARGLRYLHEE-CRIG--CIVHRDVRPNNILVTHDFT-----------ALVGDFGLA
                              .|. . .  ... .|.|..|||.  |. .   .||||.   |.||... .           . ..||||.
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLL-MCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLS

RW----QARGDTAEQTRVIGTIGY-----------------------------VAPEYAE---------TGQITEKADVYSFGLVLLEIIT
|      || .  ..  .  . ..                              |||  .         .|  |.| ||.||| .. || |
RQGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAKb_c-1.AA Pkinase 298-500 25 3.2e-35 125.62 Pfam 1-213 (293) Show / Hide 
Range on Protein: 298-500
Range on HMM: 1-213/293
Sequence Identity: 25% (56 aa)

FSKENLVAEGGFGFVYKGVLSDGQL-VAVKQHKLASRQGDREFKA-----EVEVLSSAQHRNLVTLIGYCTEGGRRILVYEFVCNG----SLNKHLSRKN
. ..  . .|.|| |||..  . .  ||||. |.  .. . . ..     |.... . .| | |.|.........  .| |.. .|    .|  ..|...
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKR-HEKSWKDQTHRRLSEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

PKPL--DWPSRQNIALGAARGLRYLHEECRIGCIVHRDVRPNNILVTHDFTA----LVGDFGLAR-WQARGDTAEQTRVIGTIGYVAPEYAE-TGQITEK
 ...  ..   .....  .||| |.|..     |.|||. | |||. .. .      ..|||||.  .        | . ||..|.|||       .. |
HGCFYFSEWECKFYMYQILRGLEYCHSM----GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFD-Y-NNS-MTTFCGTPWYMAPEVIRGGQYYGPK

ADVYSFGLVLLEIITGRPAFD
.|..|.|..| | ..||| |.
VDMWSCGCILYEMLCGRPPFP
Kinase IRAKb_c-1.AA LRRK 298-507 24 9.8e-35 120.3 In-house 1-291 (351) Show / Hide 
Range on Protein: 298-507
Range on HMM: 1-291/351
Sequence Identity: 24% (73 aa)

FSKENLVAEGGFG-FVYKGVLSD---------------------------GQLVAVKQHKLA---------------------SRQGD------------
. .|... .|||| |||.. . .                           .| ||.|. ..                      | |..            
LKIEEQIGRGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVEDMDQNHEDCCRA

-REFKAEVEVLSSAQHRNLVTLIGYCTEGGRRILVYEFVCNGSLNKHLS--RKNP----K-PLDWPSRQNIALGAARGLRYLHEECRIGC--IVHRDVRP
 |||  || ..|. .| |.| |.|.| .   ...| |.. .|.|...|.  ....    |  ..|  .. |||  |.|..|||         |.||| ..
FREFRHEVWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH----NPPIIHRDLKS

NNILV-TH-----------DFTALVGDFGLAR-WQARGDT-AEQTRVIGTIGYVAPEYAETG---QITEKADVYSFGLVLLEIITGR-PAFDSYQQPGQ
 |||. ..           . .| ..|||. | .|. . . |   .. |..|..|||    .   . |||.|.||||..| |..|.. ..|| .. ...
PNILLWSSPQNHSPNYPNAHVCAKIADFGISRMFQCFHMGVAK--GCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQHHPFDEHDFFDH
Kinase IRAKb_c-1.AA MLK 298-496 26 6e-33 111.68 In-house 1-233 (291) Show / Hide 
Range on Protein: 298-496
Range on HMM: 1-233/291
Sequence Identity: 26% (63 aa)

FSKENLVAEGGFGFVYKGVLSDGQL-----VAVKQHK----LASRQG--DREFKAEVEVLSSAQHRN----LVTLIGYCTEGGR-RILVYEFVCNGSLNK
.  .  . .|.|| |.||.   ...     ||||...     .|. .  ...|. |.. |.  .|.|     . . | |.. .    .| |.. .|||. 
IQFHEWIGSGSFGKVWKGRW-RNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYN

HLSRKNPKPL------------DWPSRQNIALGAARGLRYLHEECRIGCIVHRDVRPNNILVTH------DFTALVGDFGLAR-WQARGDTAEQTRVIGT
 |  ...|.             |  .  |.||  |||. |||.. .   |.|||  . |||...      . |. . |||..| |. ....   .  .||
VLHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPK-PIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMCTN--MMSNAGT

IGYVAPEY---AETGQITEKADVYSFGLVLLEIITGR
  . |||    .. .. .||.||.|.|.|| |..|..
YAWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase IRAKb_c-1.AA TK-Unique 298-494 25 9.6e-33 110.28 In-house 1-234 (294) Show / Hide 
Range on Protein: 298-494
Range on HMM: 1-234/294
Sequence Identity: 25% (61 aa)

FSKENLVAEGGFGFVYKGVLSD-------GQLVAVKQHK-LASRQGDREFKAEVEVLSSAQ-HRNLVTLIGYCTEGG-RRILVYEFVCNGSLNKHLSRKN
.  .... || ||.|..| ..         . ||||..|  |. . ...|. | .....   | |.|...|.||. . .  ...|.. .|.| ..| .. 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

PK------------------------PLDWPSRQNIALGAARGLRYLHE-ECRIGCIVHRDVRPNNILVTHDFTALVGDFGLAR-WQARGDTAEQ-TRVI
|.                        |..  .  ..| . |.|. ||..  ..|   ||||.   |.|.|.|... ..|||.||  ...|... . ..  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI---VHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGR

GTIGYVAPEYAE--TGQI-TEKADVYSFGLVLLEIIT
  | . |||.    .|.. |.| ||.||| .. || |
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase IRAKb_c-1.AA TyrKc 298-569 24 2.3e-32 114.77 SMART 1-280 (280) Show / Hide 
Range on Protein: 298-569
Range on HMM: 1-280/280
Sequence Identity: 24% (72 aa)

FSKENLVAEGGFGFVYKGVLSDGQLVAVKQHKLASRQGDREFKAEVEVLSSA--QHRNLVTLIGYCTEG-------GRRILVYEFVCNGSLNKHLSRKNP
 ...    || || ||||...  . ||||  |  .    ..|  | .....   .| |.| |.|.||..       .   .| |....|.|...| .. |
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

KPLDWPSRQNIALGAARGLRYLHEECRIGCIVHRDVRPNNILVTHDFTALVGDFGLARWQARG--------DTAE----QTRVIGTIGYVAPEYAETGQI
| | ..   .... .|.| .|||.     ...|||    |.||....|. ..||||.|    .                ...    |   |||   .|  
K-LCMKDLLSFCWQIACGMEYLHSK----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYGKF

TEKADVYSFGLVLLEIITGRPAFDSYQQPGQQHLPDWATPFLAARAAHELLDERIDESSVDEY-------ELINMVTAASLCIQKDPSKRPKMTQVCSSL
|.| ||.||| .. || |       |  . ||        .. .. ..|.....      ...           | .  . | . ||..|| ...... .
TTKSDVWSFGVCMWEIFTY--GQQPYPGMIQQ--------MMSNQEVIEYVKQGYRMPQPPNDYPMSFVCCPDEMYQIMKQCWHEDPEDRPTFSEIHECF
Kinase IRAKb_c-1.AA Pkinase_Tyr 298-446 28 2.3e-32 110.21 Pfam 1-159 (270) Show / Hide 
Range on Protein: 298-446
Range on HMM: 1-159/270
Sequence Identity: 28% (47 aa)

FSKENLVAEGGFGFVYKGVLS-----DGQLVAVKQHKLASRQGD---REFKAEVEVLSSA-QHRNLVTLIGYCT-EGGR--RILVYEFVCNGSLNKHLSR
 ..     || || ||||..      ... ||||  |  . . .   ..| .|......  .| |.| |.| || .|.    ..| |....|.| ..| .
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

K--NPKPLDWPSRQNIALGAARGLRYLHEECRIGCIVHRDVRPNNILVTHDFTALVGDFGLAR
.  ...||. .   ....  |.|. ||..      ..|||..  |.|||..... ..||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN----CIHRDLAARNCLVTENNVVKICDFGLAR
Kinase IRAKb_c-1.AA CZAK 298-496 31 1e-27 97.79 In-house 1-219 (279) Show / Hide 
Range on Protein: 298-496
Range on HMM: 1-219/279
Sequence Identity: 31% (70 aa)

FSKENLVAEGGFGFVYKGVLSDGQLVAVKQHKLASRQGDRE------FKAEVEVLSSAQHRNLVTLIGYCTEGG--RRILVYEFVCNGSLNKHLSRKNPK
.  .  . .| || |||..   |  ||.|   . .     |      |  || ..|   | | |  .| |.|.|   .  | |.   ||| . |  .   
LKFGQTIGQGFFGEVYKAYWR-GKDVAIKIIHRNQFRNKDENKEENMFQKEVSIMSKLCHPNCVQFLGACSEDGPNHHCIVMEWMGGGSLRRLLTDHYFY

PLDWPS-RQNIALGAARGLRYLHEECRIGCIVHRDVRPNNILVTHDFT-------------ALVGDFGLARWQARGDTAEQTRVIGTIGYVAPEYAETGQ
 .  |. . |.|.  |||  |||   . . |.|||    |||  |  |             . . |||| |    . . | |  .| . . |||      
HKQNPHLQWNMAIDIARGMNYLHDNWKPNPILHRDLSSRNILLDHSYTPKNPVVSSRQDIICKINDFGLSREMMEQPF-EMTQTMGCLCWMAPECFKGEN

ITEKADVYSFGLVLLEIITGR
 |||.||||||..| .|||..
YTEKVDVYSFGMILWCIITCD
Kinase IRAKb_c-1.AA STE 298-497 19 6.4e-27 92.16 In-house 1-266 (359) Show / Hide 
Range on Protein: 298-497
Range on HMM: 1-266/359
Sequence Identity: 19% (55 aa)

FSKENLVAEGGFGFVYKGVLSD----------------GQLVAVKQHKLASRQG-----------------DREFKAEVEVLSSAQ--HRNLVTLIGYCT
. .   . .|.|| |||..  .                |...|.|| .| . .                    ... |.....  .  | | |. .|.. 
WEGIEKIGKGAFGTVYKAMNHKNCNIHKTGEVENNGETGEIMAIKQMNLENCNNKDENQENQELENKNHEEMQQILKEIKIMKKCNHMHPNIVKYYGCYF

EGG-------RRILVYEFVCNGSLNKHLSRKN--PKPLD----------WPSRQNIALGAARG-LRYLHEECRIGCIVHRDVRPNNILVTHDFTALVGDF
 .|          .. |.. .||| . . .|   .|||.           .    |.    .| | |||.      |.|||. | |||.     .   ||
KEGHNHKNDDELWICMEYMDGGSLDDIIKHKYGCGKPLNHNRQHQHRFPESQIAYICRQILKGLLYYLHSHH----IIHRDIKPANILL-----VKLCDF

GLARWQARG--------------DTAEQT-RVIGTIGYVAPEYAET------GQITEKADVYSFGLVLLEIITGRP
|..   .                ......  ..||  . |||  .       .. ..|.|..|.|....| .||.|
GVCGQLTDSMANIQSNNIIDCIETMQQKRNTFVGTP-WMAPEVIQQNGQGRDKGYDTKCDIWSLGCTIIEMATGKP
Kinase IRAKb_c-1.AA TK 551-569 36 0.00046 8.67 In-house 468-486 (486) Show / Hide 
Range on Protein: 551-569
Range on HMM: 468-486/486
Sequence Identity: 36% (7 aa)

CIQKDPSKRPKMTQVCSSL
| ..||..|| ..|. . |
CWHYDPEDRPTFSQLHEQL
Kinase IRAKb_c-1.AA MLK 551-569 42 0.000463 10.13 In-house 273-291 (291) Show / Hide 
Range on Protein: 551-569
Range on HMM: 273-291/291
Sequence Identity: 42% (8 aa)

CIQKDPSKRPKMTQVCSSL
| . ||.|||.. |. . |
CWNQDPHKRPSFRQIVQHL
Kinase IRAKb_c-1.AA Pkinase_Tyr 467-494 50 0.002528 11.88 Pfam 182-209 (270) Show / Hide 
Range on Protein: 467-494
Range on HMM: 182-209/270
Sequence Identity: 50% (14 aa)

APEYAETGQITEKADVYSFGLVLLEIIT
|||   .|  |.| ||.||| .. ||.|
APECINYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAKb_c-1.AA LRRK 550-571 40 0.011183 5.28 In-house 330-351 (351) Show / Hide 
Range on Protein: 550-571
Range on HMM: 330-351/351
Sequence Identity: 40% (9 aa)

LCIQKDPSKRPKMTQVCSSLAV
.| | || |||...|. . |  
HCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAKb_c-1.AA Pkinase_Tyr 550-569 30 0.01374 9.39 Pfam 251-270 (270) Show / Hide 
Range on Protein: 550-569
Range on HMM: 251-270/270
Sequence Identity: 30% (6 aa)

LCIQKDPSKRPKMTQVCSSL
.| ..||..|| .... . |
QCWHYDPEDRPTFSEIHEQL
Kinase IRAKb_c-1.AA TK-Unique 551-569 36 0.020681 4.27 In-house 276-294 (294) Show / Hide 
Range on Protein: 551-569
Range on HMM: 276-294/294
Sequence Identity: 36% (7 aa)

CIQKDPSKRPKMTQVCSSL
|.|..|..||  .|. . |
CWQWEPEERPSFRQIKHRL
Kinase IRAKb_c-1.AA TKL-Unique 551-569 36 0.022943 4.37 In-house 272-290 (290) Show / Hide 
Range on Protein: 551-569
Range on HMM: 272-290/290
Sequence Identity: 36% (7 aa)

CIQKDPSKRPKMTQVCSSL
|   |||.||  ... ..|
CWHHDPSQRPSFDEIIHRL
Kinase IRAKb_c-1.AA IRAK 544-569 26 0.032093 3.87 In-house 292-317 (317) Show / Hide 
Range on Protein: 544-569
Range on HMM: 292-317/317
Sequence Identity: 26% (7 aa)

MVTAASLCIQKDPSKRPKMTQVCSSL
|  .|. |      .|..|..| ..|
MCQCACCCGHHRANRRCDMAWVMQQL
Kinase IRAKb_c-1.AA STE 549-564 56 0.057665 2.88 In-house 335-350 (359) Show / Hide 
Range on Protein: 549-564
Range on HMM: 335-350/359
Sequence Identity: 56% (9 aa)

SLCIQKDPSKRPKMTQ
..| ||||.|||. .|
NKCLQKDPNKRPTASQ
Kinase IRAKb_c-1.AA Pkinase 551-569 38 1.146707 3.44 Pfam 273-293 (293) Show / Hide 
Range on Protein: 551-569
Range on HMM: 273-293/293
Sequence Identity: 38% (8 aa)

CIQKDPSKRPKMTQVCSS--L
|..|||.|||  .|.. .  .
CLCKDPKKRPTAEQILQHPWF