Gene IRAKb_h (S.moellendorffii)

IRAKb_h

Species: S.moellendorffii
Alias: IRAKb_h
External Links:
Annotation:

Classification

Group: TKL
Family: IRAK
Subfamily: IRAKb

Sequence

Name Sequence Type Origin Length Description Download
IRAKb_h.AA Protein None 793 None Fasta, JSON
IRAKb_h.NA RNA None 2382 None Fasta, JSON
IRAKb_h.kin_dom Protein Kinase Domain None 270 None Fasta, JSON

Protein domain

Protein domains of IRAKb_h.AA. The domains are annotated by HMM profiles from Pfam and SMART, as well as in-house data which includes HMMs of each individual kinase group, family and subfamily. Here is domain list in details, including sequence identity, significance and alignment. In particular, you can find can find the best hit kinase group/family/subfamily, which is helpful to understand the relationship between kinases.Kinase domain and best hit kinase group/family/subfamily are highlighted in red and blue. Visualized by pviz.

Usage: Zoom in selected region by dragging mouse and zoom out by double-clicking.

Show/hide domain list
Domain Protein name Domain Name Range Identity (%) Significance Score Profile Source Profile Range (length) Alignment
Kinase IRAKb_h.AA TKL 436-700 20 2.3e-55 190.24 In-house 1-364 (364) Show / Hide 
Range on Protein: 436-700
Range on HMM: 1-364/364
Sequence Identity: 20% (78 aa)

LAEGGFGSVHRGVLPE---------GQVVAVKQHKLASSQGDVE-------------------------FCSEVEVLSCAQ--HRNVVMLIGYCMEDSR-
. .|||| |..|..           |..||||. |  ... . .                         |. |.|.... .  | |.| ..|||.. .  
IGSGGFGEVYKGKWRGWGGKCPSDTGKDVAVKKFKSHNDDEFTKNSQENNDNNNYSDMQLNDPEASWFRFFEEEEIMMMSRLRHPNIVQFMGYCCCPPCG

------------RLLVYEFICNNS-LDAHLYGKTMDPLEWKYRQRVAIGAARGLRYLHE----ECRVG-CIVHRDMRPNNILLTHDYE------------
              .|.|.. . | |. ..         |  | | |...|||. |||      |.    |.|||  ..|||.  ...            
CVCMHPVGPWGQLCIVMEYCPGGSLLHYLH---------WHQRCRWALDIARGMNYLHSMNPKWCT-KPPIIHRDLKSKNILVDENWTNVSNYMYNPNAD

--PMVGDFGLARWQPDGELGVETR------------------VIGTFGYLAPEYTQ----------------SGQITEKADVYSFGIVLLELVTGRKAID
  . ..||||.|.    .    |                   ..||....|||  .                ... .||.||||||||| |..|...   
WCCKICDFGLSRFMSQSGNMNDTMTTMMESAEHQNNRKTTMTQCGTPRWMAPEVLRGQMNYTEKVGIDEFCKGFEYSEKCDVYSFGIVLWEILTRCR---

ISRPKGQQCLTEWARPLLRKRVYR---ELVDPKLCGEFEKDEVT--------------C---MLHAAFLCISRDPNTRPRMSQVLRIL
            .. .  . .. .   |.   . | .... ..               |   |   .  | . ||. || ....| .|
-----------PYYDYPYMPMIFQDPFEEMFMMVCDKGLRPPIPPIWQNHHKMCPCPDCPPSMKKLMQDCWDHDPEKRPSFQEILKRL
Kinase IRAKb_h.AA IRAK 430-700 29 3.1e-52 179.86 In-house 1-317 (317) Show / Hide 
Range on Protein: 430-700
Range on HMM: 1-317/317
Sequence Identity: 29% (94 aa)

FSQANFLAEGGFGSVHRGVLPEGQ-VVAVK----QHKLASSQGDVEFCS---EVEVLSCAQHRNVVMLIGYCMEDSRRLLVYEFICNNSLDAHLYGKT-M
|...| . ||||| | ||..     ..|||      ..   . ...| .   |..|..  .| |.| | ||| | .   |||... | || . | . .  
FHKDNRIGEGGFGCVYRGQWKNTTGIYAVKKLKEMADMSWNEHWQRFQQSYNELKVCCRCRHPNIVPLYGYCTERQCHCLVYPYMPNGSLEDRLWCQDGQ

DP---LEWKYRQRVAIGAARGLRYLHEECRVGCIVHRDMRPNNILLTHDYEPMVGDFGLARWQ---PDGELGVE-----TRVIGTFGYLAPEYTQ--SGQ
.|   |.|  |  ...|.|.|...||.      | |.|  . ||||  . .|  .||||.|     .. | ..       .|.||  |..||.    .||
CPPKPLSWHQRCSICWGTACGIQFLHQNHPCTPIIHGDIKSANILLDQHFTPKICDFGLHRFGHPASHKEKQTYTCMMTSHVRGTTWYMPPEFIRDPQGQ

ITEKADVYSFGIVLLELVTGRKAIDISRPK-----------GQQCLT---------------EWARPLLRKRVYRELVDPKLCGEFEKDEVTCMLHAAFL
.| | |||||||||||..||..| .  ||.            ...                  || |  |  .|  ..| .. .  .....  |. .|  
LTKKTDVYSFGIVLLEVLTGCRAVYDDRPEHYYLKDLCEEIMEEWGHLDSCQSTLWVGVATDAWAAP-RRMQIYEKFID-HRMPPCPPNMEKEMCQCACC

CISRDPNTRPRMSQVLRIL
|  .  | |. | .|.  |
CGHHRANRRCDMAWVMQQL
Kinase IRAKb_h.AA TKL-Unique 432-627 29 1.8e-35 122.6 In-house 1-224 (290) Show / Hide 
Range on Protein: 432-627
Range on HMM: 1-224/290
Sequence Identity: 29% (67 aa)

QANFLAEGGFGSVHRGVLPEGQVVAVKQHK-LASSQGD--VEFCSEVEVLSCAQ-HRNVVMLIGYCM----EDSRRLLVYEFICNNSLDAHLYG------
  | . |||.|.| .|. . |  ||.|| . ...|  .   || .|| .... . | |.| ..||||      ... .| |..  .||. .|        
FWNKIGEGGYGQVYKGKWR-GYPVAIKQFHPNEDSSNEMMQEFENEVNWMKKLHYHPNIVHYMGYCMDHQVYPPNMCIVMEYCPGGSLYDVLHQNNNNNN

--KTMDPLEWKYRQRVAIGAARGLRYLHEECRVGCIVHRDMRPNNILLTHD-----YEPMVGDFGLARWQPDGELGVETRV--------IGTFGYLAPEY
  .   .| .. | . || .|.|. ||| .     | |||... |.|.. .     .   . ||||.. .     .  ..         .|.| ..||| 
NNNNNCKLNMQQRVKMAIDIAQGMYYLHHCEPP--IIHRDLKSSNFLVDNNSNIAEWNIKICDFGLSKFNSKINKMTNNEHKGTRNQTRCGSFRWMAPEV

TQS--GQITEKADVYSFGIVLLELVTG
. .   |..||.||||||||| |..|.
LRMNFCQYSEKSDVYSFGIVLWEIATR
Kinase IRAKb_h.AA Pkinase 430-628 22 3.1e-31 111.53 Pfam 1-209 (293) Show / Hide 
Range on Protein: 430-628
Range on HMM: 1-209/293
Sequence Identity: 22% (50 aa)

FSQANFLAEGGFGSVHRGVLPEGQV-VAVKQHKLASSQGDVE-----FCSEVEVLSCAQHRNVVMLIGYCMEDSRRLLVYEFICNN----SLDAHLY---
.     . .|.||.| ...    .  ||||. |. .   ...       ||....   .| |.| |.........  .| |.  .     .| ...    
YHIGRKIGSGSFGCVYKCHHKGTGKIVAVKIIKKRHEKSWKDQTHRRL-SEIQIMKRLNHPNIVRLYDWFEDKDHIYMVMEYCEGGLYVMDLFDYISTWR

GKTMDPLEWKYRQRVAIGAARGLRYLHEECRVGCIVHRDMRPNNILLTHDYEP----MVGDFGLAR---WQPDGELGVETRVIGTFGYLAPEYTQ-SGQI
....  ....  ....   .||| |.|..     |.|||. | |||. .....     ..|||||.   . ... . .   . || .|.|||  . .  .
HGCFY-FSEWECKFYMYQILRGLEYCHSM----GIIHRDLKPENILIDNNGHIDACVKICDFGLAKQFDY-NNS-MTT---FCGTPWYMAPEVIRGGQYY

TEKADVYSFGIVLLELVTGR
. |.|..|.|..| |...||
GPKVDMWSCGCILYEMLCGR
Kinase IRAKb_h.AA TK 430-626 14 2e-30 98.61 In-house 1-389 (486) Show / Hide 
Range on Protein: 430-626
Range on HMM: 1-389/486
Sequence Identity: 14% (55 aa)

FSQANFLAEGGFG---SVHRGVLPEG--------------------------QVVAVKQHKLASSQGDVE-----------------FCSEVEVLSC--A
    . | || ||    |..| . ..                          . ||||. |. ... . |                 ...| .....   
ITLGKKLGEGQFGSFGEVYKGEWRGRNPWNGKRFPCHMTVTLKCKNGKEGGKTPVAVKMLKEGDAMSQEEFFDEEMHDRDGGEDFLEEAEEMKMMCHSLG

QHRNVVMLIGYCMED------------SRRLLVYEFICNNS----LDAHLY--GKTMDPLEWKYRQR---------------------------------
.| |.| |.|.|...               ..| |. .. .    |. .|    ... . . ..  .                                 
HHPNIVRLYGVCTQGEPKPCFEVVVHQEPWMIVMEYMPHGDMDGSLRDYLRKCRPKFQHEQDCPDNQHNKYPPSKLHHCMKGDITYSHESNSPCPEEQDY

--------------------------------------VAIGAARGLRYLHEE-CRVG--CIVHRDMRPNNILLTHDYE-----------PMVGDFGLAR
                                       .  .|.|..|||.  |. .   .||||    |.|.....              ..||||.|
DDDLIKDHPPPLTTKDLLQMAWQWCLTCKHQLTMHQLLMCWQIACGMEYLHSKNCE-FIQNFVHRDLAARNCLVGENNVCKWHFDGCGPVCKIADFGLSR

-----WQPDGELGVETRVIGTFG----------------------------YLAPEYTQSGQ---------ITEKADVYSFGIVLLELVT
        | . . . .. .. |                            ..|||  ....          |.| ||.|||... |..|
QGSGVLARDIYSDDDYYRKSSYGTGRPMWPFEDDPWQDYYRQQSGGKLPIRWMAPECLNDRVFSEAEKYGKFTTKSDVWSFGVLMWEIFT
Kinase IRAKb_h.AA TK-Unique 430-626 24 1e-27 92.75 In-house 1-234 (294) Show / Hide 
Range on Protein: 430-626
Range on HMM: 1-234/294
Sequence Identity: 24% (57 aa)

FSQANFLAEGGFGSVHRGVLPE-------GQVVAVKQHKLASSQGD-VEFCSEVEVLSCAQ-HRNVVMLIGYCMEDS-RRLLVYEFICNNSLDAHLYGKT
.   . . || || |.|| . .        ..||||..|  ... |  .| .| ....    | |.|...|.|.... . ....|.. . .|. .|  . 
LEVGDVIGEGAFGQVWRGEVWGIWKHWDKQKCVAVKMLKDNATDTDKQDFLKEIQMMKELGDHPNIVQCLGCCTKSDEPWMIIMEYCPCGNLQHYLRTCR

MD---------------------PLE-WKYRQRV--AIGAARGLRYLHE-ECRVGCIVHRDMRPNNILLTHDYEPMVGDFGLAR-WQPDGELGVE-TRVI
..                     ..|  .... .  |.. |.|. ||..  ...   ||||    |.|||.|..  ..|||.||  . .|..  . ..  
PAMRQHQTYGNLKFDFHHMPDKPRTEPISPKDLYHFAWQIACGMEYLASQRKKI---VHRDLCARNVLLTEDKVCKICDFGMARDVYTNGVYSMMCSQGR

GTFGYLAPEYTQ--SGQI-TEKADVYSFGIVLLELVT
    ..|||. .   |.. |.| ||.|||... |..|
IPIRWMAPESLKCYHGMYHTTKSDVWSFGVLMWEIFT
Kinase IRAKb_h.AA S_TKc 430-705 20 2.1e-27 98.3 SMART 1-231 (231) Show / Hide 
Range on Protein: 430-705
Range on HMM: 1-231/231
Sequence Identity: 20% (58 aa)

FSQANFLAEGGFGSVHRGVLPE-GQVVAVKQHKLASSQGDVEFCSEVEVLSCAQHRNVVMLIGYCMEDSRRLLVYEFICN--NSLDAHLYGKTMDP----
.   . . .|.||.|....  . |..||.|. |         ...|...|.  .| |.| |.... . ..  .| |.. .   .|  ..  .   .    
YEILRKIGKGAFGKVYKCRHKKTGRIVAIKIIK-------EHIRREIQILKK-HHPNIVKLYDVFQD-DHLYMVMEYCDGDLGDLFDYIKKRGRHGLRFP

LEWKYRQRVAIGAARGLRYLHEECRVGCIVHRDMRPNNILLTHDYEPMVGDFGLARWQPDGELGVETRVIGTFGYLAPEYTQSGQITE-KADVYSFGIVL
.     ....   ...| |.|.      |.|||  | ||||..  . ...||||||          | ..||  |.|||     . .  |.|..|.|..|
FPE-HARFYMYQICCALEYCHSHG----IIHRDLKPENILLDE--HIKICDFGLARQL--------TTFCGTPWYMAPEVL---GYGKCKCDWWSCGCIL

LELVTGRKAIDISRPKGQQCLTEWARPLLRKRVYRELVDPKLCGEFEKDEVTCMLHAAFLCISRDPNTRPRMSQVLR----ILEGEMI
 |...|.   .      .| . .  .                           ...    |  .||. ||   ..|.    |   . .
YEMLCGYPPFP-----QMQMMFKKIG------------------------SPEAKDFIRKCLQKDPEKRPTA-EALQDEWDIKCHPWF
Kinase IRAKb_h.AA LRRK 438-628 24 1.9e-26 90.55 In-house 9-279 (351) Show / Hide 
Range on Protein: 438-628
Range on HMM: 9-279/351
Sequence Identity: 24% (67 aa)

EGGFG-SVHRGVLPE---------------------------GQVVAVKQHKLA---------SSQG----------DVEFCS----------------E
.|||| .|.|. .                             .| ||.|. ..          .| .           ||. .                |
RGGFGTFVYRAKWRGQPVHVCRMHQKMLQPYMYQGARNSYDMCQWVAIKKWNRDPMTIDNDCNNSNNNNNLNNNNSEQVED-MDQNHEDCCRAFREFRHE

VEVLSCAQHRNVVMLIGYCMEDSRRLLVYEFICNNSLDAHLYGKTMDP-------LEWKYRQRVAIGAARGLRYLHEECRVGC--IVHRDMRPNNILL-T
| ..|  .| |.| |.|.|..   . .| |.. . .|. .|  |  |.       . |  ....|.  |.|..|||         |.||| .. |||| .
VWIMSHLNHPNIVSLKGFCIHP--LCMVMEYAPHGDLYHFLHNKKQDGFHFMKAHISWMLKLKIALQIAKGMEYLHSH----NPPIIHRDLKSPNILLWS

HD--Y------EPM---VGDFGLAR-WQPDGELGVETRVIGTFGYLAPEYTQSG---QITEKADVYSFGIVLLELVTGR
..  .      ...   ..|||. | .|.... ||  .. |..|..|||  . .   . |||.|.||||..| ||.|..
SPQNHSPNYPNAHVCAKIADFGISRMFQCFHM-GVAKGCVGNPGWMAPEIMRYNGEEEYTEKVDCYSFGMILWELLTRQ
Kinase IRAKb_h.AA Dicty4 430-627 29 8.9e-26 83.09 In-house 1-213 (277) Show / Hide 
Range on Protein: 430-627
Range on HMM: 1-213/277
Sequence Identity: 29% (64 aa)

FSQANFLAEGGFGSVHRGVLPEGQVVAVKQHKLASSQGDV------EFCSEVEVLSCAQHRNVVMLIGYCM----EDSRRLLVYEFICNNSLDAHLYGK-
    ... .|.||.|..|    |. ||||  || . . ..      ||  ||. ..  .| |.. . |.|     . .. . | |.    .| . |  . 
INIEQRIGKGSFGEVYKGTW-RGKEVAVK--KLNNHNQNFDENMLNEFRKEVHIMCKIRHPNICLFMGACTAPRSHPGKMCIVTEYMPKGNL-YSLLHDK

-----TMDPLEWKYRQR---VAIGAARGLRYLHE-ECRVGCIVHRDMRPNNILLTHDYEPMVGDFGLAR-WQPDGELGV-ETRVIGTFGYLAPEYTQSGQ
      ...|.|  . |    |. ||||. .||.  ..   |.|||  . |.|   ..   |.||||..  ... ...   . ..|| .. |||  ..  
PSEQQQSIKLDWPLIKRAMRMAFDAARGMNWLHCCNPV---IIHRDLKSHNLLVDKNWRVKVCDFGLSQYMKKHEDHKDNQMTACGTPCWMAPEVMMHQP

ITEKADVYSFGIVLLELVTG
 .|||||||||||| |..|.
YNEKADVYSFGIVLWEILTR
Kinase IRAKb_h.AA MLK 430-628 23 6.2e-25 83.52 In-house 1-233 (291) Show / Hide 
Range on Protein: 430-628
Range on HMM: 1-233/291
Sequence Identity: 23% (56 aa)

FSQANFLAEGGFGSVHRGVLPEGQ----VVAVKQHKL------ASSQGDVEFCSEVEVLSCAQHRN----VVMLIGYCMED-SRRLLVYEFICNNSLDAH
.    .. .|.||.|..|.         .||||...        ..  . .|  |.. |.  .|.|    .. . | | .. .  ..| |.. . ||   
IQFHEWIGSGSFGKVWKGRWRNKDIVAKIVAVKRVRARIFDKSDTYCEQWDFEMECRHLRILSHPNNHPCIIQFYGVCLQPPCHFCIVMEYCEGGSLYNV

LYGKTMDPL----------EWKYRQRV--AIGAARGLRYLHEECRVGCIVHRDMRPNNILLTH------DYEPMVGDFGLAR-WQPDGELGVETRVIGTF
|.|..  .             .  . .  |   |||. |||.. ..  |.|||  . |||...      .    . |||..| |.  .     .  .||.
LHGARSKWMDANHNQKNDRVYDHDHAMNWALQCARGMHYLHSMAPK-PIIHRDLKSHNILIDEICHDMHHGTLKICDFGTSRDWHQMC--TNMMSNAGTY

GYLAPEYT---QSGQITEKADVYSFGIVLLELVTGR
 . ||| .   .... .||.||.|.|.|| |..|..
AWMAPEVIQQFRCEKYSEKCDVWSWGVVLWEMLTRE
Kinase IRAKb_h.AA DRK 439-626 31 1.3e-22 73.47 In-house 10-197 (258) Show / Hide 
Range on Protein: 439-626
Range on HMM: 10-197/258
Sequence Identity: 31% (60 aa)

GGFGSVHRGVLPEGQVVAVKQHKLASSQ-GDV--EFCSEVEVLSCAQHRNVVMLIGYCMEDSRRLLVYEFICNNSLDAHLYGKTMDPLEWKYRQRVAIGA
|..| | ||    |  ||||  ..      .   ||  |.....   | |..  .| | . .  . . |..   ||   |    .  ..|  . . .. .
GNYGEVFRGTW-RGTQVAVKMLFNHNINDENFLNEFHREINLMCQLRHPNICQFMGTCNNPPDICICMEYMPRGSLYNILHDESIE-MDWPLMKQMMFDC

ARGLRYLHEECRVGCIVHRDMRPNNILLTHDYEPMVGDFGLA-RWQPDGELGVETRVIGTFGYLAPEYTQSGQITEKADVYSFGIVLLELVT
|.|. |||  |.   |.|||    | |    .   | ||||. |..   . .     .|| .  |||   .   |||||||||.||| |.||
AKGMIYLH--CCNPIIIHRDLKSHNLLVDEHWQVKVADFGLSTRFKKHKQHKFAMTMCGTPCWTAPEVLRNQRYTEKADVYSFAIVLWECVT
Kinase IRAKb_h.AA Pkinase_Tyr 430-578 26 3.2e-18 62.35 Pfam 1-159 (270) Show / Hide 
Range on Protein: 430-578
Range on HMM: 1-159/270
Sequence Identity: 26% (43 aa)

FSQANFLAEGGFGSVHRGVLP-----EGQVVAVKQHKLASSQGD---VEFCSEVEVLSCA-QHRNVVMLIGYCM-EDSR--RLLVYEFICNNSLDAHLYG
 .    | || ||.|..|..      ... ||||  |  ... .    .| .|.....   .| |.| |.| |. ..     ..| |. .. .|. .|  
ITFGKKLGEGAFGEVYKGTWKGDPDNTKIPVAVKMLKEGAMHEQNCREDFMREAKIMKQLGHHPNIVRLYGVCTDQGEPNQIYIVMEYMPHGDLLDYLRK

K--TMDPLEWKYRQRVAIGAARGLRYLHEECRVGCIVHRDMRPNNILLTHDYEPMVGDFGLAR
.    .||  |     ..  |.|. ||..      ..||| .  |.|.|..    ..||||||
HREDKQPLTMKDLLQMCWQIAKGMEYLESKN----CIHRDLAARNCLVTENNVVKICDFGLAR
Kinase IRAKb_h.AA TyrKc 430-700 21 4.5e-18 67.3 SMART 1-280 (280) Show / Hide 
Range on Protein: 430-700
Range on HMM: 1-280/280
Sequence Identity: 21% (66 aa)

FSQANFLAEGGFGSVHRGVLPEGQVVAVKQHKLASSQGDVEFCSEVEVLSCA--QHRNVVMLIGYCMED-------SRRLLVYEFICNNSLDAHL--YGK
 .    | || || |..|..   . ||||  |  .     .|..| ....    .| |.| |.|.|...          ..| |. .. .|. .|  ...
ITLGKKLGEGAFGEVYKGTWK--IQVAVKMLKEDA---REDFMREARIMCKLGGHHPNIVRLYGVCTQQGRNFMYIEPLMIVMEYMPHGDLKDYLRKHRP

TMDPLEWKYRQRVAIGAARGLRYLHEECRVGCIVHRDMRPNNILLTHDYEPMVGDFGLARWQPDG-------ELGVET---RVI--GTFGYLAPEYTQSG
.   | .|     .. .|.| .|||.     ...|||    |.|.....   ..||||.|   |.       .  . .             .|||  . |
K---LCMKDLLSFCWQIACGMEYLHSK----NCIHRDLAARNCLVGENHTVKISDFGLSRDIYDDDQQGESKDYYRKKEHKGGKTMLPIRWMAPECINYG

QITEKADVYSFGIVLLELVTGRKAIDISRPKGQQ----CLTEWARPLLRKRVYRELVDP----KLCGEFEKDEVTC---MLHAAFLCISRDPNTRPRMSQ
  |.| ||.|||... |. |     .   |   .    .  . .. ..... ...  .          |    |.|   |      |  .||. ||..|.
KFTTKSDVWSFGVCMWEIFT-----YGQQPYPGMIQQMMSNQEVIEYVKQGYRMPQPPNDYPMS----F----VCCPDEMYQIMKQCWHEDPEDRPTFSE

VLRIL
. ...
IHECF
Kinase IRAKb_h.AA LISK 435-578 31 2.4e-17 52.7 In-house 1-153 (296) Show / Hide 
Range on Protein: 435-578
Range on HMM: 1-153/296
Sequence Identity: 31% (50 aa)

FLAEGGFGSVHRGVLP-EGQVVAVKQHKL-----ASSQGDVEFCSEVEVLSCAQHRNVVMLIGYCME-DSRRLLVYEFICNNSLDAHLYGKTMD----PL
 . .|.||.| .| .   |||.|.|. .              .  ||... . .|.|.|  .| | . |..  .| |.|  |  | | | | ||    ||
EIGKGFFGKVYKGTHRQTGQVMAIKMIHRQPNDPNDPEYQKFMLREVQMMKNLRHPNIVQFMGVCYHNDGQLHIVTEYI--NGGDLHQYLKDMDKHKIPL

EWKYRQRVAIGAARGLRYLHEECRVGCIVHRDMRPNNILLT----HDYEPMVGDFGLAR
 |. | . | . |.|..|||.     .|.|||   .|.|.      ...  |.|||.||
PWPQRVKIALDIACGMSYLHSM----NIIHRDLKSKNCLVRENDNNQWRIKVCDFGFAR
Kinase IRAKb_h.AA LISK 609-630 59 5.7e-09 25.06 In-house 217-238 (296) Show / Hide 
Range on Protein: 609-630
Range on HMM: 217-238/296
Sequence Identity: 59% (13 aa)

TEKADVYSFGIVLLELVTGRKA
.|..||.||||||.|..|..||
DESCDVFSFGIVLCEIITRVKA
Kinase IRAKb_h.AA DRK 682-702 42 2.8e-05 13.89 In-house 238-258 (258) Show / Hide 
Range on Protein: 682-702
Range on HMM: 238-258/258
Sequence Identity: 42% (9 aa)

CISRDPNTRPRMSQVLRILEG
| . ||  || | ..| .|| 
CWNEDPQHRPSMQECLERLEA
Kinase IRAKb_h.AA MLK 682-700 36 0.000175 11.62 In-house 273-291 (291) Show / Hide 
Range on Protein: 682-700
Range on HMM: 273-291/291
Sequence Identity: 36% (7 aa)

CISRDPNTRPRMSQVLRIL
| . ||. || ..|.. .|
CWNQDPHKRPSFRQIVQHL
Kinase IRAKb_h.AA Pkinase_Tyr 598-629 42 0.001023 13.21 Pfam 181-213 (270) Show / Hide 
Range on Protein: 598-629
Range on HMM: 181-213/270
Sequence Identity: 42% (14 aa)

LAPEYTQSGQITEKADVYSFGIVLLELVT-GRK
.|||  . |  |.| ||.|||... |..| |..
MAPECINYGKFTTKSDVWSFGVLMWEIFTYGEQ
Kinase IRAKb_h.AA Dicty4 682-702 30 0.001348 8.06 In-house 255-277 (277) Show / Hide 
Range on Protein: 682-702
Range on HMM: 255-277/277
Sequence Identity: 30% (7 aa)

CISRDPNTRPRMSQVLRI--LEG
| . ||. || ..... .  || 
CWDHDPQHRPSFEEIIQRRILEH
Kinase IRAKb_h.AA TK 682-700 42 0.002325 6.27 In-house 468-486 (486) Show / Hide 
Range on Protein: 682-700
Range on HMM: 468-486/486
Sequence Identity: 42% (8 aa)

CISRDPNTRPRMSQVLRIL
| ..||. ||..||... |
CWHYDPEDRPTFSQLHEQL
Kinase IRAKb_h.AA LRRK 681-702 36 0.004763 6.61 In-house 330-351 (351) Show / Hide 
Range on Protein: 681-702
Range on HMM: 330-351/351
Sequence Identity: 36% (8 aa)

LCISRDPNTRPRMSQVLRILEG
.| . ||. || .||.. .|. 
HCWQHDPKKRPHFSQIVKRLSQ
Kinase IRAKb_h.AA TK-Unique 682-700 31 0.073266 2.35 In-house 276-294 (294) Show / Hide 
Range on Protein: 682-700
Range on HMM: 276-294/294
Sequence Identity: 31% (6 aa)

CISRDPNTRPRMSQVLRIL
|....|  ||  .|.. .|
CWQWEPEERPSFRQIKHRL
Kinase IRAKb_h.AA LISK 679-700 31 0.08137 1.45 In-house 275-296 (296) Show / Hide 
Range on Protein: 679-700
Range on HMM: 275-296/296
Sequence Identity: 31% (7 aa)

AFLCISRDPNTRPRMSQVLRIL
.| |.. ||..||  . ....|
CFDCCKYDPKNRPSFKEIVQWL
Kinase IRAKb_h.AA Pkinase_Tyr 681-700 35 0.120197 6.2 Pfam 251-270 (270) Show / Hide 
Range on Protein: 681-700
Range on HMM: 251-270/270
Sequence Identity: 35% (7 aa)

LCISRDPNTRPRMSQVLRIL
.|   ||. ||..|.....|
QCWHYDPEDRPTFSEIHEQL